{"id":22045,"date":"2023-12-26T17:13:16","date_gmt":"2023-12-26T09:13:16","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=22045"},"modified":"2023-12-26T17:13:18","modified_gmt":"2023-12-26T09:13:18","slug":"1%e5%8c%ba9-3%ef%bc%81%e4%b8%a4%e4%b8%aa%e5%a4%a7%e5%9e%8b%e4%b8%b4%e5%ba%8a%e6%95%b0%e6%8d%aeepic%e5%92%8cukb%e5%bc%ba%e5%bc%ba%e8%81%94%e5%90%88%ef%bc%8c%e5%b7%a7%e5%a6%99%e8%a7%a3%e5%af%86","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=22045","title":{"rendered":"1\u533a9.3+\uff01\u4e24\u4e2a\u5927\u578b\u4e34\u5e8a\u6570\u636eEPIC\u548cUKB\u5f3a\u5f3a\u8054\u5408\uff0c\u5de7\u5999\u89e3\u5bc6\u80bf\u7624\u98ce\u9669\u5173\u7cfb\uff01"},"content":{"rendered":"<p>\u5c0f\u4f19\u4f34\u4eec\uff0c\u4e0a\u65b0\u4e86\u4e0a\u65b0\u4e86\uff01\u5927\u961f\u5217\u6570\u636e\u5206\u6790\u7684\u4f18\u52bf\u5df2\u7ecf\u4e0d\u8a00\u800c\u55bb\u4e86\uff01\u8fd8\u6ca1\u4e0a\u8f66\u7684\u5c0f\u4f19\u4f34\u53ef\u5f97\u6293\u7d27\u4e86\u54df\uff01\u5f53\u4f60\u7ecf\u5e38\u770b\u5230\u8fd9\u7c7b\u6587\u7ae0\u7684\u65f6\u5019\uff0c\u518d\u4e0d\u8ddf\u4e0a\u53ef\u80fd\u771f\u7684\u5c31OUT\u4e86\u54e6\uff01<\/p>\n<p>\u5c0f\u4e91\u4e00\u5982\u65e2\u5f80\u7684\u6765\u548c\u5927\u5bb6\u5206\u4eab\u4e00\u7bc7\u6765\u81ea\u4e24\u4e2a\u5927\u578b\u961f\u5217\u6570\u636e\u7684\u4e34\u5e8a\u5206\u6790\uff0c\u8be5\u6587\u53ef\u8c13\u662f\u4e00\u4e3e\u591a\u5f97\u554a\uff0c\u9996\u5148\u662f\u79d1\u7814\u4eba\u5458\u53d1\u6587\u5bb9\u6613\uff0c\u7136\u540e\u662f\u7814\u7a76\u7ed3\u679c\u6570\u636e\u5177\u6709\u4e34\u5e8a\u6307\u5bfc\u610f\u4e49\uff0c\u6700\u540e\u662f\u5bf9\u4e8e\u533b\u9662\u548c\u60a3\u8005\u90fd\u662f\u798f\u97f3\uff0c\u63a8\u52a8\u533b\u5b66\u9886\u57df\u7684\u53d1\u5c55\u3002\u770b\u5c0f\u4e91\u5938\u7684\u8fd9\u4e48\u597d\uff0c\u7a76\u7adf\u6709\u4f55\u9ad8\u8d85\u4e4b\u5904\u5462\uff0c\u5148\u770b\u770b\u8be5\u6587\u5982\u4e0b\u51e0\u4e2a\u4f18\u52bf\uff0c\u518d\u968f\u7740\u5c0f\u4e91\u6df1\u5165\u4e86\u89e3\u5168\u6587\uff01<\/p>\n<p>1\u3001<strong>\u6b64\u9879\u7814\u7a76\u835f\u8403\u5206\u6790\u4e86\u6765\u81ea\u6b27\u6d32\u591a\u4e2a\u56fd\u5bb6\u7684\u4e24\u4e2a\u5927\u578b\u9884\u671f\u6210\u4eba\u961f\u5217\u7684\u4e2a\u4f53\u6c34\u5e73\u53c2\u4e0e\u8005\u7684\u6570\u636e<\/strong>\uff1b\u5206\u522b\u4e3a\u6b27\u6d32\u764c\u75c7\u4e0e\u8425\u517b\u524d\u77bb\u6027\u8c03\u67e5\uff08EPIC\uff09\u548c\u82f1\u56fd\u751f\u7269\u94f6\u884c\uff08UKB\uff09\uff01<\/p>\n<p>2\u3001<strong>\u8fd9\u9879\u7814\u7a76\u636e\u4f5c\u8005\u5206\u6790\u53ef\u77e5\uff0c\u662f\u76ee\u524d\u4f7f\u7528\u591a\u56fd\u6570\u636e\u901a\u8fc7\u786e\u5b9a\u5fc3\u810f\u4ee3\u8c22\u75be\u75c5\uff08CMD\uff09\u6765\u8c03\u67e5BMI\u548c\u764c\u75c7\u53d1\u75c5\u7387\u4e4b\u95f4\u7684\u5173\u7cfb\u7684\u6700\u5927\u89c4\u6a21\u7814\u7a76\u3002<\/strong><\/p>\n<p>3\u3001<strong>\u4f5c\u8005\u7814\u7a76\u5206\u6790\u4e2d\uff0c\u4ee5\u4e00\u79cd\u65f6\u53d8\u7684\u65b9\u5f0f\u5bf9\u5173\u8054\u8fdb\u884c\u5efa\u6a21\uff0c\u8003\u8651\u5230\u53d1\u751f\u7684\u6162\u6027\u75be\u75c5\u7684\u987a\u5e8f\uff1b\u5e76\u4e14\u7814\u7a76\u6700\u540e\u8fdb\u884c\u4e86\u654f\u611f\u6027\u5206\u6790\uff0c\u66f4\u8fdb\u4e00\u6b65\u7684\u89e3\u51b3\u4e86\u6f5c\u5728\u7684\u504f\u5dee\uff0c\u63d0\u9ad8\u4e86\u5206\u6790\u6548\u7387<\/strong>\uff01\u4e24\u9879\u5927\u578b\u961f\u5217\u6570\u636e\u7684\u8054\u5408\u5206\u6790\uff0c\u5c06\u591a\u9879\u764c\u75c7\u7c7b\u522b\u4e0eBMI\u8fdb\u884c\u98ce\u9669\u9884\u6d4b\uff0c\u6570\u636e\u5f3a\u6709\u529b\u7684\u8bc1\u660e\u4e86\u7814\u7a76\u7ed3\u679c\uff0c\u975e\u5e38\u503c\u5f97\u5165\u624b\u7684\u4e00\u9879\u5927\u89c4\u6a21\u6570\u636e\u4e34\u5e8a\u5206\u6790\uff0c<strong>\u8fd8\u5728\u89c2\u671b\u7684\u5c0f\u4f19\u4f34\u8d76\u5feb\u8054\u7cfb\u5c0f\u4e91\uff0c\u6211\u4eec\u7ed9\u4f60\u6700\u5168\u9762\u7684\u6280\u672f\u670d\u52a1\uff0c\u5feb\u5feb\u6765\u590d\u73b0\u5427\uff01<\/strong><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"252\" class=\"wp-image-22047\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-1.png?resize=640%2C252\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-1.png?w=1051 1051w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-1.png?resize=300%2C118 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-1.png?resize=1024%2C403 1024w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-1.png?resize=768%2C303 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-1.png?resize=600%2C236 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<ul>\n<li>\u9898\u76ee\uff1a\u60a3\u6709\u548c\u4e0d\u60a3\u6709\u5fc3\u810f\u4ee3\u8c22\u75be\u75c5\u7684\u6210\u5e74\u4eba\u7684\u4f53\u91cd\u6307\u6570\u548c\u764c\u75c7\u98ce\u9669\uff1a\u6765\u81eaEPIC\u548c\u82f1\u56fd\u751f\u7269\u94f6\u884c\u524d\u77bb\u6027\u961f\u5217\u7814\u7a76\u7684\u8bc1\u636e<\/li>\n<li>\u6742\u5fd7\uff1a<em>BMC Medicine<\/em><\/li>\n<li>\u5f71\u54cd\u56e0\u5b50\uff1aIF= 9.2994<\/li>\n<li>\u53d1\u8868\u65f6\u95f4\uff1a2023\u5e7411\u670823\u65e5<\/li>\n<\/ul>\n<p><strong>\u7814\u7a76\u80cc\u666f<\/strong><\/p>\n<p>\u60a3\u6709\u548c\u4e0d\u60a3\u6709\u5fc3\u8840\u7ba1\u75be\u75c5\uff08CVD\uff09\u548c\/\u62162\u578b\u7cd6\u5c3f\u75c5\uff08T2D\uff09\u7684\u6210\u5e74\u4eba\u4e4b\u95f4\uff0c\u4e0e\u8f83\u9ad8\u4f53\u91cd\u6307\u6570\uff08BMI\uff09\u76f8\u5173\u7684\u764c\u75c7\u98ce\u9669\u662f\u5426\u5b58\u5728\u5dee\u5f02\u5c1a\u4e0d\u6e05\u695a\u3002\u672c\u7814\u7a76\u7684\u4e3b\u8981\u76ee\u7684\u662f\u8bc4\u4f30BMI\u548cCVD\/T2D\u4e0e\u764c\u75c7\u98ce\u9669\u7684\u5355\u72ec\u548c\u8054\u5408\u5173\u8054\u3002<\/p>\n<p><strong>\u6570\u636e\u6765\u6e90<\/strong><\/p>\n<p>\u82f1\u56fd\u751f\u7269\u94f6\u884c\uff08UKB\uff09\u6570\u636e\uff1a344094\u540d\u53c2\u4e0e\u8005\u3002\u6d89\u53ca2006\u5e74\u81f32010\u5e74\u671f\u95f4\u5728\u82f1\u56fd\u768422\u4e2a\u4e2d\u5fc3\u767b\u8bb0\u7684\u7ea650\u4e07\u540d\u5e74\u9f84\u572840-69\u5c81\u4e4b\u95f4\u7684\u4e2a\u4eba\u3002<\/p>\n<p>\u6b27\u6d32\u764c\u75c7\u4e0e\u8425\u517b\u524d\u77bb\u6027\u8c03\u67e5\uff08EPIC\uff09\u6570\u636e\uff1a233249\u540d\u53c2\u4e0e\u8005\u3002\u6765\u81ea10\u4e2a\u6b27\u6d32\u56fd\u5bb6\u768423\u4e2a\u7814\u7a76\u4e2d\u5fc3\uff0c\u7ea652\u4e07\u540d\u5e74\u9f84\u572835-69\u5c81\u4e4b\u95f4\u7684\u4e2a\u4eba\u3002<\/p>\n<p>\u4e0e\u80a5\u80d6\u76f8\u5173\u7684\u764c\u75c7\u88ab\u5b9a\u4e49\u4e3a\u8111\u819c\u7624\u3001\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u3001\u98df\u9053\u817a\u764c\uff0c\u4ee5\u53ca\u7532\u72b6\u817a\u764c\u3001\u7edd\u7ecf\u540e\u4e73\u817a\u764c\u3001\u80c6\u56ca\u764c\u3001\u80c3\u764c\u3001\u809d\u764c\u3001\u80f0\u817a\u764c\u3001\u80be\u764c\u3001\u5375\u5de2\u764c\u3001\u5b50\u5bab\u764c\u3001\u7ed3\u80a0\u764c\u548c\u76f4\u80a0\u764c\uff0c\u764c\u75c7\u8bca\u65ad\u6570\u636e\u7531NHS\u4e2d\u592e\u767b\u8bb0\u518c\uff08NHSCR\uff09\u83b7\u53d6\u3002<\/p>\n<p><strong>\u7814\u7a76\u601d\u8def<\/strong><\/p>\n<p>\u4f5c\u8005\u4f7f\u7528Cox\u6bd4\u4f8b\u98ce\u9669\u56de\u5f52\u6765\u4f30\u8ba1BMI\u4e0e\u80a5\u80d6\u76f8\u5173\u764c\u75c7\u53d1\u75c5\u7387\u4e4b\u95f4\u7684\u5173\u8054\u7684\u591a\u53d8\u91cf\u8c03\u6574\u98ce\u9669\u6bd4(HR)\u548c95%\u7f6e\u4fe1\u533a\u95f4(CI)\uff0c\u8fdb\u800c\u4f30\u8ba1\u603b\u4f53\u764c\u75c7\u4e0eBMI\u548c\u4e24\u79cd\u5fc3\u810f\u4ee3\u8c22\u4e4b\u95f4\u7684\u4e58\u6cd5\u76f8\u4e92\u4f5c\u7528\u75be\u75c5\uff08CMD\uff09\uff1b\u7136\u540e\u4f30\u8ba1\u8d85\u91cd\/\u80a5\u80d6\u548cCMD\u72b6\u6001\u7c7b\u522b\u7684\u5355\u72ec\u5173\u8054\u548c\u8054\u5408\u5173\u8054\u7684HR\u548c95%CI\uff1b\u6700\u540e\u901a\u8fc7\u76f8\u4e92\u4f5c\u7528\u5bfc\u81f4\u7684\u76f8\u5bf9\u8d85\u989d\u98ce\u9669(RERI)\u91cf\u5316\u4e86\u52a0\u6027\u76f8\u4e92\u4f5c\u7528\u3002<\/p>\n<p><strong>\u4e3b\u8981\u7ed3\u679c<\/strong><\/p>\n<p>\u5728\u603b\u5171577343\u540d\u7814\u7a76\u53c2\u4e0e\u8005(UKB\u4e2dn=344094\uff1bEPIC\u4e2dn=233249)\u4e2d\uff0cUKB\u548cEPIC\u961f\u5217\u4e2d\u5206\u522b\u670953%\u548c62%\u7684\u5973\u6027\u3002\u88681\u548c\u88682\u5206\u522b\u62a5\u544a\u4e86\u4e24\u4e2a\u7814\u7a76\u4eba\u7fa4\u7684\u57fa\u7ebf\u7279\u5f81\u3002\u5728\u4e24\u4e2a\u961f\u5217\u4e2d\uff0c\u4e0e\u5176\u4ed6\u7814\u7a76\u53c2\u4e0e\u8005\u76f8\u6bd4\uff0c\u80a5\u80d6\u7814\u7a76\u53c2\u4e0e\u8005(\u4f53\u91cd\u6307\u6570\u226530\u516c\u65a4\/\u5e73\u65b9\u7c73)\u5f80\u5f80\u5177\u6709\u8f83\u4f4e\u7684\u6559\u80b2\u6c34\u5e73\u548c\u8f83\u5c11\u7684\u4f53\u529b\u6d3b\u52a8\u3002\u5728UKB\u4e2d\uff0c10.9\u5e74(\u56db\u5206\u4f4d\u6570\u8303\u56f4\uff0cIQR\uff1a10.1-11.7)\u7684\u4e2d\u4f4d\u6570\u968f\u8bbf\u671f\u95f4\uff0c\u603b\u5171\u53d1\u751f\u4e8632549\u4f8b\u7b2c\u4e00\u539f\u53d1\u764c(9.5%\u7684\u53c2\u4e0e\u8005)\uff0c\u5176\u4e2d\u5305\u62ec12526\u4f8b\u4e0e\u80a5\u80d6\u6709\u5173\u7684\u764c\u75c7(\u5176\u4e2d66%\u662f\u5973\u6027)\u3002\u5728EPIC\u4e2d\uff0c10.9\u5e74(IQR\uff1a9.4-12.2)\u7684\u4e2d\u4f4d\u6570\u968f\u8bbf\u671f\u95f4\uff0c\u53d1\u751f\u4e8619833\u4f8b\u7b2c\u4e00\u539f\u53d1\u764c(8.3%\u7684\u53c2\u4e0e\u8005)\uff0c\u5176\u4e2d\u5305\u62ec7892\u4f8b\u4e0e\u80a5\u80d6\u6709\u5173\u7684\u764c\u75c7(\u5176\u4e2d76%\u662f\u5973\u6027)\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"617\" height=\"679\" class=\"wp-image-22048\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-2.png?resize=617%2C679\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-2.png?w=617 617w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-2.png?resize=273%2C300 273w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-2.png?resize=600%2C660 600w\" sizes=\"(max-width: 617px) 100vw, 617px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u88681 \u6309\u4f53\u91cd\u6307\u6570\u5206\u7c7b\u7684UKB\u7814\u7a76\u4eba\u7fa4\u7684\u57fa\u7ebf\u7279\u5f81<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"604\" height=\"781\" class=\"wp-image-22049\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-3.png?resize=604%2C781\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-3.png?w=604 604w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-3.png?resize=232%2C300 232w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-3.png?resize=600%2C776 600w\" sizes=\"(max-width: 604px) 100vw, 604px\" data-recalc-dims=\"1\" \/><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"37\" class=\"wp-image-22050\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-4.png?resize=640%2C37\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-4.png?w=1009 1009w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-4.png?resize=300%2C18 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-4.png?resize=768%2C45 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-4.png?resize=600%2C35 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u88682 \u6309\u4f53\u91cd\u6307\u6570\u5206\u7c7b\u7684EPIC\u4e2d\u7814\u7a76\u4eba\u7fa4\u57fa\u7ebf\u7279\u5f81<\/p>\n<p><strong>1\u3001BMI\u548c\u5fc3\u810f\u4ee3\u8c22\u75be\u75c5\u72b6\u6001\u5bfc\u81f4\u80a5\u80d6\u76f8\u5173\u764c\u75c7\u7684\u98ce\u9669<\/strong><\/p>\n<p>\u5728\u591a\u53d8\u91cf\u8c03\u6574\u7684\u57fa\u7840\u6a21\u578b\u4e2d\uff0c\u4f5c\u8005\u5ffd\u7565\u4e86CMD\u72b6\u6001\uff0c\u89c2\u5bdf\u5230BMI\u4e0e\u80a5\u80d6\u76f8\u5173\u7684\u764c\u75c7\u98ce\u9669\u4e4b\u95f4\u5b58\u5728\u9884\u671f\u7684\u6b63\u76f8\u5173\u6027\u3002\u4f53\u91cd\u6307\u6570\u6bcf\u589e\u52a01SD(~5kg\/m<sup>2<\/sup>)\uff0cEPIC\u548cUKB\u7684HR\u5206\u522b\u4e3a1.10(95%CI\uff1a1.08~1.12)\u548c1.16(95%CI\uff1a1.14~1.18)(<strong>\u88683<\/strong>)\u3002\u5bf9CMD\u53ca\u5176\u6301\u7eed\u65f6\u95f4\u7684\u8c03\u6574\u51cf\u5f31\u4e86\u8fd9\u4e9b\u5173\u8054(<strong>\u88683<\/strong>)\u3002\u5728\u4e3b\u8981\u6a21\u578b\u4e2d\uff0c\u4f5c\u8005\u901a\u8fc7CMD\u72b6\u6001\u4f30\u8ba1\u5173\u8054\u3002\u5728\u4e24\u4e2a\u961f\u5217\u7684\u835f\u8403\u5206\u6790\u4e2d\uff0c\u4f53\u91cd\u6307\u6570\u6bcf\u589e\u52a0\u4e00\u4e2aSD\uff0c\u5728\u6ca1\u6709\u6162\u6027\u75be\u75c5\u7684\u53c2\u4e0e\u8005\u4e2d\u4e0e\u80a5\u80d6\u76f8\u5173\u764c\u75c7\u7684\u98ce\u9669\u5448\u6b63\u76f8\u5173(\u6c47\u603bHR\uff1a1.11\uff0c95%CI\uff1a1.07-1.16)\uff0c\u7c7b\u4f3c\u5730\uff0c\u5728\u6709T2D\u6216\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u53c2\u4e0e\u8005\u4e2d(<strong>\u56fe1<\/strong>)\uff0c\u51e0\u4e4e\u6ca1\u6709\u8bc1\u636e\u8868\u660e\u4e58\u6027\u4ea4\u4e92\u4f5c\u7528(\u6240\u6709P-\u4ea4\u4e92\u4f5c\u7528\u2265\u4e3a0.17)(<strong>\u88683<\/strong>)\u3002\u5728UKB\u7684\u5fc3\u8840\u7ba1\u75be\u75c5\u53c2\u4e0e\u8005\u4e2d\u89c2\u5bdf\u5230\u6700\u5f3a\u7684\u6b63\u76f8\u5173\u6027\uff0cHR\u7b49\u4e8e1.19(95%CI\uff1a1.12-1.25)(<strong>\u56fe1\u548c\u88683<\/strong>)\u3002\u603b\u53d8\u5f02\u6027\u7684\u9ad8\u6bd4\u4f8b\u5f52\u56e0\u4e8e\u7814\u7a76\u4e4b\u95f4\u7684\u5f02\u8d28\u6027(I2=92%)\uff0c\u5bf9\u4e8e\u6ca1\u6709CMD\u7684\u6a21\u578b(<strong>\u56fe1<\/strong>)\u5f88\u53ef\u80fd\u662f\u7531\u4e8e\u7cbe\u786e\u7684\u98ce\u9669\u4f30\u8ba1\u548c\u82f1\u56fd\u751f\u7269\u5e93\u53c2\u4e0e\u8005\u4e2d\u80a5\u80d6\u7387(22%)\u4e0eEPIC(15%)\u7684\u4e0d\u540c\u3002\u7ed3\u679c\u5728\u7537\u6027\u548c\u5973\u6027\u4e4b\u95f4\u6ca1\u6709\u5b9e\u8d28\u6027\u5dee\u5f02\uff0c\u9664\u4e86\u5fc3\u8840\u7ba1\u75be\u75c5\uff0c\u4f5c\u8005\u5728\u5973\u6027\u4e2d\u89c2\u5bdf\u5230BMI\u4e0e\u80a5\u80d6\u76f8\u5173\u764c\u75c7\u98ce\u9669\u4e4b\u95f4\u7684\u5173\u8054\u6bd4\u7537\u6027\u66f4\u5f3a(HR\u6c47\u603b\u5973\u6027\uff1a1.22\uff0c95%CI\uff1a1.13-1.31\uff1bHR\u6c47\u603bHR\u7537\u6027\uff1a1.07\uff0c95%CI\uff1a0.96-1.19)\u3002<\/p>\n<p>\u5728\u654f\u611f\u6027\u5206\u6790\u4e2d\uff0c\u5bf9UKB\u4e2d\u4e8c\u7532\u53cc\u80cd\u6216\u4ed6\u6c40\u7c7b\u836f\u7269\u7684\u4f7f\u7528\u8fdb\u884c\u4e86\u8fdb\u4e00\u6b65\u7684\u8c03\u6574\uff0c\u6216\u8005\u5bf9\u4ece\u4e0d\u5438\u70df\u7684\u4eba\u8fdb\u884c\u4e86\u5206\u6790\uff0c\u5f97\u51fa\u4e86\u7c7b\u4f3c\u4e8e\u4e3b\u8981\u6a21\u578b\u7684\u98ce\u9669\u4f30\u8ba1\u3002<\/p>\n<p>\u4f5c\u8005\u8fd8\u8bc4\u4f30\u4e86BMI\u4e0e\u975e\u80a5\u80d6\u76f8\u5173\u764c\u75c7\u98ce\u9669\u4e4b\u95f4\u7684\u5173\u7cfb\uff0c\u4f5c\u4e3a\u9634\u6027\u5bf9\u7167\u7ed3\u679c\uff0c\u98ce\u9669\u4f30\u8ba1\u57fa\u672c\u4e0a\u4e3a\u7a7a\u3002\u8fd8\u8bc4\u4f30\u4e86BMI\u4e0e\u975e\u80a5\u80d6\u76f8\u5173\u764c\u75c7\u98ce\u9669\u4e4b\u95f4\u7684\u5173\u8054\uff0c\u5c06\u5176\u4f5c\u4e3a\u9634\u6027\u5bf9\u7167\u7ed3\u679c\uff0c\u98ce\u9669\u4f30\u8ba1\u57fa\u672c\u4e3a\u96f6\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"166\" class=\"wp-image-22051\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-5.png?resize=640%2C166\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-5.png?w=1015 1015w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-5.png?resize=300%2C78 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-5.png?resize=768%2C200 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-5.png?resize=600%2C156 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u88683 \u5728EPIC\u548cUKB\u961f\u5217\u4e2d\uff0c\u901a\u8fc7\u786e\u5b9a\u5fc3\u810f\u4ee3\u8c22\u6027\u75be\u75c5\uff0cBMI(\u6bcf1\u4e2a\u6807\u51c6\u5dee\u589e\u91cf1)\u4e0e\u80a5\u80d6\u76f8\u5173\u764c\u75c7\u98ce\u9669\u4e4b\u95f4\u7684\u5173\u7cfb<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"406\" class=\"wp-image-22052\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-6.png?resize=640%2C406\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-6.png?w=844 844w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-6.png?resize=300%2C190 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-6.png?resize=768%2C487 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-6.png?resize=600%2C380 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u56fe1 EPIC\u548cUKB\u961f\u5217\u4e2d\u5fc3\u810f\u4ee3\u8c22\u6027\u75be\u75c5\u72b6\u6001\u7684BMI\u548c\u80a5\u80d6\u76f8\u5173\u764c\u75c7\u98ce\u9669<\/p>\n<p><strong>2\u3001\u8d85\u91cd\u548c\/\u6216\u80a5\u80d6\u4e0e\u5fc3\u810f\u4ee3\u8c22\u75be\u75c5\u4e0e\u80a5\u80d6\u76f8\u5173\u764c\u75c7\u98ce\u9669\u7684\u8054\u5408\u5173\u8054<\/strong><\/p>\n<p>\u88684\u663e\u793a\u4e86\u8d85\u91cd\/\u80a5\u80d6\u548cCMD\u4e0e\u80a5\u80d6\u76f8\u5173\u764c\u75c7\u98ce\u9669\u7684\u5355\u72ec\u548c\u8054\u5408\u5173\u8054\u3002\u5728UKB\u4e2d\uff0c\u6709\u8bc1\u636e\u8868\u660e\uff0c\u8d85\u91cd\u548c\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u8054\u5408\u5173\u8054\u9ad8\u4e8e\u5355\u72ec\u5173\u8054\u7684\u603b\u548c\u3002\u4e0e\u4f53\u91cd\u6b63\u5e38\u7684\u53c2\u4e0e\u8005(\u4f53\u91cd\u6307\u6570&lt;25\u516c\u65a4\/\u5e73\u65b9\u7c73)\u548c\u6ca1\u6709\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u53c2\u4e0e\u8005(\u53c2\u7167\u7ec4)\u76f8\u6bd4\uff0c\u540c\u65f6\u63a5\u89e6\u4f53\u91cd\u6307\u6570\u548c\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u53c2\u4e0e\u8005(\u4f53\u91cd\u6307\u6570\u2265&lt;25\u516c\u65a4\/\u5e73\u65b9\u7c73\u548c\u5fc3\u8840\u7ba1\u75be\u75c5)\u60a3\u80a5\u80d6\u76f8\u5173\u764c\u75c7\u7684\u98ce\u9669\u662f\u5bf9\u7167\u7ec4\u76843.4\u500d(95%CI\uff1a2.95-3.95)\u3002<\/p>\n<p>\u4f53\u91cd\u6b63\u5e38\u4f46\u6709\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u53c2\u4e0e\u8005\u548c\u8d85\u91cd\/\u80a5\u80d6\u65e0\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u53c2\u4e0e\u8005\u7684HR\u5206\u522b\u4e3a2.68(95%\u53ef\u4fe1\u533a\u95f42.23-3.23)\u548c1.23(95%\u53ef\u4fe1\u533a\u95f41.18-1.28)(\u88684)\u3002\u8fd9\u79cd\u76f8\u52a0\u4ea4\u4e92\u4f5c\u7528\u5bf9\u5e94\u7684RERI\u4e3a0.50(95%CI\uff1a0.02-0.98)\uff0c\u8fd9\u610f\u5473\u7740\u8054\u5408\u5173\u8054\u6bd4\u5355\u72ec\u5173\u8054\u7684\u603b\u548c\u9ad80.5\u500d\u3002\u80a5\u80d6(\u4f53\u91cd\u6307\u6570\u226530 kg\/m2)\u548c\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u8054\u5408\u5173\u8054\u5bfc\u81f4\u76f8\u5bf9\u8f83\u5f3a\u7684RERI(0.66\uff0c95%CI\uff1a0.16-1.17)\u3002<\/p>\n<p>\u7136\u800c\uff0c\u8fd9\u4e9b\u76f8\u4e92\u4f5c\u7528\u5728EPIC(\u88684)\u4e2d\u6ca1\u6709\u5f97\u5230\u8bc1\u5b9e\uff0c\u4e24\u4e2a\u961f\u5217\u7684\u835f\u8403\u5206\u6790\u4e2dRERI\u7684CI\u90fd\u4e3a\u7a7a\uff1b\u4f8b\u5982\uff0c\u80a5\u80d6(\u4f53\u91cd\u6307\u6570\u226530kg\/m2)\u548c\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u835f\u8403\u5206\u6790RERI\u4e3a0.39(95%CI\u22120.17-0.96)(\u56fe2)\u3002\u5728\u6027\u522b\u5206\u5c42\u5206\u6790\u4e2d\uff0cRERI\u5305\u62ec\u7537\u6027\u4e2d\u7684\u96f6\uff0c\u800c\u5728\u5973\u6027\u4e2d\uff0c\u80a5\u80d6\u548c\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u8054\u5408\u5173\u8054\u591a\u4e8e\u76f8\u52a0(\u6982\u8981RERI\uff1a0.90 95%CI\uff1a0.34-1.45)\u3002<\/p>\n<p>\u5728\u8054\u5408\u6548\u5e94\u7684\u654f\u611f\u6027\u5206\u6790\u4e2d\uff0c\u8fdb\u4e00\u6b65\u8c03\u6574\u4e8c\u7532\u53cc\u80cd\u6216\u4ed6\u6c40\u7c7b\u836f\u7269\u7684\u4f7f\u7528\u4e0d\u4f1a\u6539\u53d8\u7ed3\u679c\uff0c\u800c\u5728UKB\u5bf9\u4ece\u4e0d\u5438\u70df\u7684\u4eba\u8fdb\u884c\u7684\u5206\u6790\u663e\u793a\uff0c\u80a5\u80d6\u548c\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u8054\u5408\u5173\u8054\u5177\u6709\u66f4\u9ad8\u7684\u6b63\u76f8\u52a0\u4ea4\u4e92\u4f5c\u7528(RERI\uff1a0.83\uff0c95%CI\uff1a0.03-1.64)\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"362\" class=\"wp-image-22053\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-7.png?resize=640%2C362\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-7.png?w=1029 1029w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-7.png?resize=300%2C170 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-7.png?resize=1024%2C579 1024w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-7.png?resize=768%2C434 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-7.png?resize=600%2C339 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u88684 \u5728EPIC\u548cUKB\u961f\u5217\u4e2d\uff0c\u8d85\u91cd\u548c\/\u6216\u80a5\u80d6(\u4f53\u91cd\u6307\u6570\u226525\u516c\u65a4\/\u5e73\u65b9\u7c73\u6216\u4f53\u91cd\u6307\u6570\u226530\u516c\u65a4\/\u5e73\u65b9\u7c73)\u4e0e\u5fc3\u810f\u4ee3\u8c22\u6027\u75be\u75c5\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u5bfc\u81f4\u80a5\u80d6\u76f8\u5173\u764c\u75c7\u7684\u76f8\u5bf9\u989d\u5916\u98ce\u9669<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"550\" class=\"wp-image-22054\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-8.png?resize=640%2C550\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-8.png?w=984 984w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-8.png?resize=300%2C258 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-8.png?resize=768%2C660 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22045-8.png?resize=600%2C515 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u56fe2 \u5728EPIC\u548cUKB\u961f\u5217\u4e2d\uff0c\u7531\u4e8e\u8d85\u91cd\/\u80a5\u80d6\u548c\u5fc3\u810f\u4ee3\u8c22\u6027\u75be\u75c5\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\uff0c\u80a5\u80d6\u76f8\u5173\u764c\u75c7\u7684\u76f8\u5bf9\u8d85\u989d\u98ce\u9669\u3002<\/p>\n<p><strong>3\u3001BMI\u548c\u5fc3\u810f\u4ee3\u8c22\u75be\u75c5\u72b6\u6001\u7684\u603b\u764c\u75c7\u98ce\u9669<\/strong><\/p>\n<p>\u5728\u591a\u53d8\u91cf\u8c03\u6574\u57fa\u7840\u6a21\u578b\u4e2d\uff0c\u5ffd\u7565CMD\u72b6\u6001\uff0cBMI(\u6bcf1SD)\u4e0e\u603b\u4f53\u764c\u75c7\u98ce\u9669\u6b63\u76f8\u5173\uff0cEPIC\u548cUKB\u7684HR\u503c\u5206\u522b\u4e3a1.04(95%\u53ef\u4fe1\u533a\u95f41.02-1.05)\u548c1.05(95%\u53ef\u4fe1\u533a\u95f4\uff1a1.04-1.06))\u3002\u5bf9CMD\u53ca\u5176\u6301\u7eed\u65f6\u95f4\u7684\u8c03\u6574\u4e0d\u4f1a\u6539\u53d8\u8fd9\u4e9b\u5173\u8054(\u9644\u52a0\u6587\u4ef61\uff1a\u8868S3)\u3002\u5728\u6309CMD\u5206\u5c42\u540e\uff0c\u5728\u4e24\u4e2a\u961f\u5217\u7684Meta\u5206\u6790\u4e2d\uff0cBMI(\u6bcf1 SD\u589e\u91cf)\u4e0e\u975eCMD\u53c2\u4e0e\u8005(\u6c47\u603bHR\uff1a1.04\uff0c95%CI\uff1a1.03-1.05)\u548c\u6709\u5fc3\u8840\u7ba1\u75be\u75c5\u53c2\u4e0e\u8005(\u6c47\u603bHR\uff1a1.05\uff0c95%CI\uff1a1.01-1.08)\u5448\u6b63\u76f8\u5173\u3002\u5728\u60a3\u6709T2D\u6216\u540c\u65f6\u60a3\u6709T2D\u548cCVD\u7684\u4e2a\u4f53\u4e2d\uff0c\u5173\u8054\u6027\u57fa\u672c\u4e0a\u4e3a\u96f6\u3002\u4e0e\u7537\u6027\u76f8\u6bd4\uff0c\u5973\u6027\u7684CMD\u8de8\u7c7b\u522b\u5173\u8054\u6027\u66f4\u5f3a\u3002\u5728\u6ca1\u6709CMD(\u6c47\u603bHR\uff1a1.06\uff0c95%CI\uff1a1.02-1.10)\u3001T2D(\u6c47\u603bHR\uff1a1.09\uff0c95%CI\uff1a1.00-1.19)\u548c\u5fc3\u8840\u7ba1\u75be\u75c5(\u6c47\u603bHR\uff1a1.13\uff0c95%CI\uff1a1.07-1.19)\u7684\u5973\u6027\u4e2d\u53d1\u73b0\u6b63\u5173\u8054\uff0c\u800c\u5728\u7537\u6027\u4e2d\u5173\u8054\u4e3a\u7a7a\u3002<\/p>\n<p>\u5728\u654f\u611f\u6027\u5206\u6790\u4e2d\uff0c\u5f53\u8fdb\u4e00\u6b65\u8c03\u6574\u4e8c\u7532\u53cc\u80cd\u548c\u4ed6\u6c40\u7c7b\u836f\u7269\u7684\u4f7f\u7528\u65f6\uff0cUKB\u4e2d\u7684\u76f8\u5173\u6027\u7c7b\u4f3c\u3002\u4e0d\u5438\u70df\u8005\u4e4b\u95f4\u7684\u8054\u7cfb\u5f80\u5f80\u6bd4\u603b\u4eba\u53e3\u4e2d\u7684\u8054\u7cfb\u7565\u5f3a\u3002<\/p>\n<p><strong>4\u3001\u8d85\u91cd\u548c\/\u6216\u80a5\u80d6\u4e0e\u5fc3\u810f\u4ee3\u8c22\u75be\u75c5\u4e0e\u603b\u764c\u75c7\u98ce\u9669\u7684\u8054\u5408\u5173\u8054<\/strong><\/p>\n<p>\u5728EPIC\u7814\u7a76\u4e2d\uff0c\u4e0e\u4f53\u91cd\u6b63\u5e38(\u4f53\u91cd\u6307\u6570&lt;25\u516c\u65a4\/\u5e73\u65b9\u7c73)\u548c\u6ca1\u6709\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u53c2\u4e0e\u8005(\u53c2\u7167\u7ec4)\u76f8\u6bd4\uff0c\u80a5\u80d6(\u4f53\u91cd\u6307\u6570\u2265\u4e3a30\u516c\u65a4\/\u5e73\u65b9\u7c73)\u548c\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u53c2\u4e0e\u8005\u60a3\u603b\u4f53\u764c\u75c7\u7684\u98ce\u9669\u9ad82\u500d(95%\u53ef\u4fe1\u533a\u95f4\uff1a1.62-2.51)\u3002UKB\u4e5f\u5f97\u5230\u4e86\u7c7b\u4f3c\u7684\u4f30\u8ba1(HR 2.59\uff0c95%CI\uff1a2.32-2.88)\u3002<\/p>\n<p>\u5728\u4e24\u4e2a\u961f\u5217\u7684\u835f\u8403\u5206\u6790\u4e2d\uff0c\u80a5\u80d6\u548c\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u8fd9\u4e9b\u8054\u5408\u5173\u8054\u8f6c\u5316\u4e3a0.28(95%CI\uff1a0.09-0.47)\u7684\u6c47\u603bRERI\u3002\u5728\u8d85\u91cd\/\u80a5\u80d6\u548c\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u53c2\u4e0e\u8005\u4e2d\uff0c\u8054\u5408\u5173\u8054\u51cf\u5f31(\u6458\u8981RERI0.11\uff0c95%CI\uff1a\u22120.07-0.29)\u3002\u5728\u6027\u522b\u5206\u5c42\u5206\u6790\u4e2d\uff0cRERI\u5305\u62ec\u7537\u6027\u4e2d\u7684\u96f6\uff0c\u800c\u5728\u5973\u6027\u4e2d\uff0c\u80a5\u80d6\u548c\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u8054\u5408\u5173\u8054\u591a\u4e8e\u76f8\u52a0(\u6458\u8981RERI\uff1a0.75\uff0c95%CI\uff1a0.35-1.16)\u4ee5\u53ca\u8d85\u91cd\/\u80a5\u80d6\u4e0eT2D\u7684\u8054\u5408\u5173\u8054(\u6458\u8981RERI\uff1a0.41\uff0c95%CI\uff1a0.02-0.81)\u3002<\/p>\n<p>\u5728\u8054\u5408\u6548\u5e94\u7684\u654f\u611f\u6027\u5206\u6790\u4e2d\uff0c\u8fdb\u4e00\u6b65\u8c03\u6574\u4e8c\u7532\u53cc\u80cd\u6216\u4ed6\u6c40\u7c7b\u836f\u7269\u7684\u4f7f\u7528\u4e0d\u4f1a\u6539\u53d8\u7ed3\u679c\uff0c\u800c\u5728UKB\u7684\u4e0d\u5438\u70df\u8005\u4e2d\u7684\u5206\u6790\u8868\u660e\uff0c\u8d85\u91cd\/\u80a5\u80d6\u4e0e\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u8054\u5408\u5173\u8054\u4ee5\u53ca\u80a5\u80d6\u4e0e\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u8054\u5408\u5173\u8054\u5b58\u5728\u6b63\u76f8\u52a0\u4ea4\u4e92\u4f5c\u7528(\u5206\u522b\u4e3aRERI\uff1a0.35\uff0c95%CI\uff1a0.01-0.70\u548cRERI\uff1a0.45\uff0c95%CI\uff1a0.07-0.83)\u3002<\/p>\n<p><strong>\u6587\u7ae0\u5c0f\u7ed3<\/strong><\/p>\n<p>\u603b\u4e4b\uff0c\u5728\u8fd9\u4e24\u4e2a\u5927\u961f\u5217\u4e2d\uff0c\u8f83\u9ad8\u7684BMI\u4e0e\u80a5\u80d6\u76f8\u5173\u764c\u75c7\u7684\u98ce\u9669\u589e\u52a0\u6709\u5173\uff1b\u8d85\u91cd\/\u80a5\u80d6\u548c\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u8054\u5408\u66b4\u9732\u53ef\u80fd\u4e0e\u603b\u4f53\u548c\u80a5\u80d6\u76f8\u5173\u764c\u75c7\u7684\u98ce\u9669\u6bd4\u4e24\u79cd\u66b4\u9732\u7684\u5355\u72ec\u5173\u8054\u7684\u603b\u548c\u66f4\u9ad8\uff1b\u4e0e\u666e\u901a\u4eba\u7fa4\u76f8\u6bd4\uff0c\u5728\u5fc3\u8840\u7ba1\u75be\u75c5\u4eba\u7fa4\u4e2d\u9884\u9632\u80a5\u80d6\u5c06\u5bfc\u81f4\u764c\u75c7\u53d1\u75c5\u7387\u7684\u66f4\u5927\u964d\u4f4e\u3002\u4e00\u9879\u975e\u5e38\u4e0d\u9519\u7684\u7814\u7a76\uff0c\u7279\u522b\u662f\u4e24\u9879\u5927\u89c4\u6a21\u6570\u636e\u961f\u5217\u7684\u8054\u5408\u5206\u6790\uff0c\u8fd9\u6837\u7684\u5927\u89c4\u6a21\u8054\u5408\u5206\u6790\uff0c\u5f80\u5f80\u6570\u636e\u5206\u6790\u7ed3\u679c\u66f4\u4e3a\u53ef\u9760\uff0c\u4e5f\u66f4\u53d7\u5ba1\u7a3f\u4e13\u5bb6\u7684\u9752\u7750\uff0c\u5173\u952e\u8fd9\u4e24\u4e2a\u516c\u5171\u6570\u636e\u961f\u5217\u975e\u5e38\u5bb9\u6613\u83b7\u53d6\uff0c<strong>\u5206\u6790\u65b9\u5f0f\u4e5f\u662f\u5c0f\u4e91\u6240\u64c5\u957f\u7684\uff0c\u627e\u5230\u601d\u8def\uff0c\u5c0f\u4e91\u5e2e\u4f60\u641e\u5b9a\u540e\u7eed\u6240\u6709\u5206\u6790\uff0c\u8bb0\u5f97\u8054\u7cfb\u5c0f\u4e91\u54e6\uff01<\/strong><\/p>\n<p><strong>\u5c0f\u4e91\u4e4b\u58f0<\/strong><\/p>\n<p><strong>\u4e91\u751f\u4fe1\u5b66\u751f\u7269\u4fe1\u606f\u5b66\u516c\u4f17\u53f7\u6301\u7eed\u4e3a\u5927\u5bb6\u5e26\u6765\u6700\u65b0\u751f\u4fe1\u601d\u8def\uff0c\u60f3\u590d\u73b0\u8fd9\u79cd\u601d\u8def\u6216\u8005\u5b9a\u5236\u66f4\u591a\u521b\u65b0\u6027\u601d\u8def\u6b22\u8fce\u76f4\u63a5call\u5c0f\u4e91\uff0c\u6211\u4eec\u56e2\u961f\u7aed\u8bda\u4e3a\u60a8\u7684\u79d1\u7814\u52a9\u529b\uff01 <\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5c0f\u4f19\u4f34\u4eec\uff0c\u4e0a\u65b0\u4e86\u4e0a\u65b0\u4e86\uff01\u5927\u961f\u5217\u6570\u636e\u5206\u6790\u7684\u4f18\u52bf\u5df2\u7ecf\u4e0d\u8a00\u800c\u55bb\u4e86\uff01\u8fd8\u6ca1\u4e0a\u8f66\u7684\u5c0f\u4f19\u4f34\u53ef\u5f97\u6293\u7d27\u4e86\u54df\uff01\u5f53\u4f60\u7ecf\u5e38\u770b\u5230\u8fd9\u7c7b\u6587\u7ae0 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/22045"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=22045"}],"version-history":[{"count":1,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/22045\/revisions"}],"predecessor-version":[{"id":22055,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/22045\/revisions\/22055"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=22045"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=22045"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=22045"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}