{"id":22455,"date":"2023-12-31T13:34:30","date_gmt":"2023-12-31T05:34:30","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=22455"},"modified":"2023-12-31T13:34:32","modified_gmt":"2023-12-31T05:34:32","slug":"%e5%b1%b1%e4%b8%9c%e5%a4%a7%e5%ad%a6%e9%bd%90%e9%b2%81%e5%8c%bb%e9%99%a2%e5%9b%a2%e9%98%9f%e4%b8%80%e9%a1%b9%e5%9f%ba%e4%ba%8e8000%e5%a4%9a%e5%90%8d%e6%82%a3%e8%80%85%e5%88%86%e6%9e%90%ef%bc%81","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=22455","title":{"rendered":"\u5c71\u4e1c\u5927\u5b66\u9f50\u9c81\u533b\u9662\u56e2\u961f\u4e00\u9879\u57fa\u4e8e8000\u591a\u540d\u60a3\u8005\u5206\u6790\uff01\u521b\u65b0\u601d\u8def\u8f7b\u677e\u62ff\u4e0b\u7eaf\u751f\u4fe1\u6587\u7ae0\uff01"},"content":{"rendered":"<p>\u5c0f\u4e91\u5206\u4eab\u4e86\u8fd9\u4e48\u4e45\u7684\u751f\u4fe1\u5206\u6790\u601d\u8def\uff0c\u89c1\u8fc7\u4e86\u5927\u5927\u5c0f\u5c0f\u7684\u75be\u75c5\u6570\u636e\u96c6\u3002\u76f8\u6bd4\u4e8e\u80bf\u7624\u76f8\u5173\u6570\u636e\u6765\u8bf4\uff0c\u975e\u80bf\u7624\u75be\u75c5\u7684\u6570\u636e\u4f1a\u5c11\u4e00\u4e9b\uff0c\u5c24\u5176\u662f\u5c0f\u79cd\u75be\u75c5\u6570\u636e\u4f1a\u66f4\u5c11\uff0c\u6709\u65f6\u5019\u53ea\u75281\u4e2a\u6570\u636e\u96c6\u4e5f\u80fd\u5206\u6790\u51fa\u4e00\u7bc7\u751f\u4fe1\u5185\u5bb9\u3002<\/p>\n<p>\u5982\u679c\u4f60\u5173\u6ce8\u7684\u6070\u5de7\u662f\u5e38\u89c1\u764c\u79cd\uff0c\u90a3\u6570\u636e\u96c6\u5c31\u6709\u5f88\u591a\u9009\u62e9\u4e86\u3002\u5f53\u7136\uff0c\u5206\u6790\u7eb3\u5165\u7684\u6570\u636e\u96c6\u8d8a\u591a\uff0c\u7ed3\u679c\u7684\u53ef\u4fe1\u5ea6\u8d8a\u9ad8\u3002<\/p>\n<p>\u8fd9\u4e0d\uff0c\u5c0f\u4e91\u53d1\u73b0\u4e86\u4e00\u7bc7\u5c71\u4e1c\u5927\u5b66\u9f50\u9c81\u533b\u9662\u7814\u7a76\u56e2\u961f\u7684\u6587\u7ae0\uff0c\u662f\u57fa\u4e8e15\u4e2a\u72ec\u7acb\u961f\u52178236\u4f8b\u4e73\u817a\u764c\u60a3\u8005\u7684\u8f6c\u5f55\u7ec4\u5b66\u6570\u636e\u8fdb\u884c\u7684\u5206\u6790\u3002\u8fd9\u6570\u636e\u91cf\u7740\u5b9e\u5c11\u89c1\uff0c\u800c\u4e14\u8fd8\u6709\u521b\u65b0\u7684\u751f\u4fe1\u65b9\u5411\u201c\u5171\u523a\u6fc0\u5206\u5b50\u201d\u52a9\u529b\uff0c\u6ca1\u6709\u505a\u5b9e\u9a8c\u5c31\u53d1\u8868\u4e867\u5206+\u7eaf\u751f\u4fe1\u6587\u7ae0\uff0c\u4e00\u8d77\u6765\u56f4\u89c2\u4e00\u4e0b\u5427~<\/p>\n<p><strong>\uff08\u5982\u679c\u6ca1\u6709\u5206\u6790\u601d\u8def\u4e5f\u53ef\u4ee5\u627e\u5c0f\u4e91\u5e2e\u5fd9\uff0c\u8d85\u591a\u4e2a\u6027\u5316\u7684\u5206\u6790\u601d\u8def\u4f9b\u4f60\u9009\u62e9~\uff09<\/strong><\/p>\n<p><img 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height=\"44\" class=\"wp-image-22460\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/unnamed-file-14.png\" alt=\"\u56fe\u7247\"><strong>\u7814\u7a76\u601d\u8def<\/strong> <img decoding=\"async\" loading=\"lazy\" width=\"50\" height=\"44\" class=\"wp-image-22461\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/unnamed-file-15.png\" alt=\"\u56fe\u7247\"><\/p>\n<p><a id=\"post-22455-OLE_LINK2\"><\/a> \u63d0\u53d6\u6765\u81ea15\u4e2a\u72ec\u7acb\u961f\u5217\u76848236\u4f8bBC\u60a3\u8005\u7684\u5168\u7ec4\u7ec7\u8f6c\u5f55\u7ec4\u5b66\u6570\u636e\u3002\u6784\u5efa\u4e86\u4e00\u4e2a\u540d\u4e3a\u201c<a 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src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22455-7.png\" srcset=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22455-7.png 894w, http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22455-7-300x264.png 300w, http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22455-7-768x676.png 768w, http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22455-7-600x528.png 600w\" sizes=\"(max-width: 894px) 100vw, 894px\" \/><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"891\" height=\"175\" class=\"wp-image-22463\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22455-8.png\" srcset=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22455-8.png 891w, http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22455-8-300x59.png 300w, http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22455-8-768x151.png 768w, http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22455-8-600x118.png 600w\" sizes=\"(max-width: 891px) 100vw, 891px\" \/><\/p>\n<p style=\"text-align: center;\">\u56fe1 \u6d41\u7a0b\u56fe<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"50\" height=\"44\" class=\"wp-image-22464\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/unnamed-file-16.png\" alt=\"\u56fe\u7247\"><strong>\u4e3b\u8981\u7814\u7a76\u7ed3\u679c<\/strong> <img decoding=\"async\" loading=\"lazy\" width=\"50\" height=\"44\" class=\"wp-image-22465\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/unnamed-file-17.png\" alt=\"\u56fe\u7247\"><\/p>\n<ol>\n<li><strong>CMS\u6a21\u578b\u7684\u5efa\u7acb\u4e0e\u9a8c\u8bc1<\/strong><\/li>\n<\/ol>\n<p>\u91c7\u7528\u5355\u56e0\u7d20Cox\u6bd4\u4f8b\u98ce\u9669\u56de\u5f52\u5206\u6790\u786e\u5b9a\u4e0e\u9884\u540e\u76f8\u5173\u7684\u5171\u523a\u6fc0\u5206\u5b50\u3002\u5728\u7b5b\u9009\u768460\u4e2a\u57fa\u56e0\u4e2d\uff0c22\u4e2a\u57fa\u56e0\u4e0e\u9884\u540e\u663e\u8457\u76f8\u5173\uff0c\u5176\u4e2d18\u4e2a\u57fa\u56e0\u88ab\u9274\u5b9a\u4e3a\u4fdd\u62a4\u56e0\u5b50\uff0c\u800c4\u4e2a\u57fa\u56e0\u88ab\u9274\u5b9a\u4e3a\u5371\u9669\u56e0\u7d20\u3002\u4f7f\u7528\u4e86\u4e24\u79cd\u72ec\u7acb\u7684\u673a\u5668\u5b66\u4e60\u65b9\u6cd5\u6765\u8bc6\u522b\u5173\u952e\u751f\u7269\u6807\u5fd7\u7269\uff0c\u5305\u62ecLASSO-Cox\u548c\u968f\u673a\u68ee\u6797\uff0c\u4e24\u79cd\u6392\u5e8f\u65b9\u6cd5\u53d6\u4ea4\u96c6\u83b7\u5f975\u4e2a\u5171\u523a\u6fc0\u5206\u5b50\uff0c\u7528\u4e8e\u8ba1\u7b97\u5171\u523a\u6fc0\u5206\u5b50\u8bc4\u5206(CMS)\u3002<\/p>\n<p>\u5c06BC\u60a3\u8005\u5206\u4e3a\u9ad8\u3001\u4f4eCMS\u4e9a\u7ec4\u3002\u751f\u5b58\u5206\u6790\u663e\u793a\uff0c\u9ad8CMS\u4e9a\u7ec4\u7684OS(\u56fe2C)\u3001\u65e0\u8f6c\u79fb\u751f\u5b58\u671f(MFS,\u56fe2A)\u548c\u65e0\u8fdb\u5c55\u95f4\u671f(PFI,\u56fe2B)\u660e\u663e\u66f4\u597d\u3002TCGA-BRCA\u961f\u5217\u4e2d\uff0c\u9ad8CMS\u7ec4\u9884\u540e\u660e\u663e\u66f4\u597d(\u56fe2D)\u3002\u5728\u5176\u4ed6\u72ec\u7acb\u7684BC\u961f\u5217\u4e2d\u8fdb\u884c\u4e86\u53ef\u91cd\u590d\u6027\u5206\u6790\uff0c\u7ed3\u679c\u4e0eMeta-BC\u961f\u5217\u76f8\u4f3c(\u56fe2E-G)\u3002<\/p>\n<p>\u5bf9\u6240\u6709\u5165\u7ec4\u7684\u516c\u5171\u961f\u5217\u8fdb\u884c\u4e86\u835f\u8403\u5206\u6790\uff0c\u5305\u62ec\u6574\u5408\u5230Meta-BC\u961f\u5217\u768412\u4e2a\u6570\u636e\u96c6\u548c3\u4e2a\u5916\u90e8\u6570\u636e\u96c6(\u56fe3M)\u3002\u57fa\u4e8e\u8ba1\u7b97\u7684CMS\uff0c\u5927\u591a\u6570\u961f\u5217\u7684\u7ed3\u679c\u76f8\u4f3c\u4e14\u663e\u8457\uff0c\u8fd9\u8868\u660eCMS\u6a21\u578b\u53ef\u4ee5\u4f5c\u4e3a\u4e00\u79cd\u4e34\u5e8a\u6709\u7528\u7684\u5de5\u5177\uff0c\u4ee5\u72ec\u7acb\u9884\u6d4b\u60a3\u8005\u9884\u540e\u3002<\/p>\n<p><strong>\uff08ps\uff1a\u673a\u5668\u5b66\u4e60\u7b97\u6cd5\u53ef\u4ee5\u7528\u5c0f\u4e91\u65b0\u5f00\u53d1\u7684\u96f6\u4ee3\u7801\u751f\u4fe1\u5206\u6790\u5c0f\u5de5\u5177\u5b9e\u73b0\uff0c\u4e91\u751f\u4fe1\u5206\u6790\u5de5\u5177\u5e73\u53f0\u5305\u542b\u8d85\u591a\u96f6\u4ee3\u7801\u5206\u6790\u548c\u7ed8\u56fe\u5c0f\u5de5\u5177\uff0c\u4e0a\u4f20\u6570\u636e\u4e00\u952e\u51fa\u56fe\uff0c\u611f\u5174\u8da3\u7684\u5c0f\u4f19\u4f34\u6b22\u8fce\u6765\u5c1d\u8bd5\u54df\uff0c\u7f51\u5740\uff1a<\/strong><a href=\"http:\/\/www.biocloudservice.com\/home.html\"><strong>http:\/\/www.biocloudservice.com\/home.html<\/strong><\/a><strong> \uff09<\/strong>\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"888\" height=\"420\" class=\"wp-image-22466\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22455-11.png\" srcset=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22455-11.png 888w, http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22455-11-300x142.png 300w, http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22455-11-768x363.png 768w, http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2023\/12\/word-image-22455-11-600x284.png 600w\" sizes=\"(max-width: 888px) 100vw, 888px\" \/><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"1476\" height=\"433\" class=\"wp-image-22467\" 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