{"id":26856,"date":"2024-01-29T17:24:05","date_gmt":"2024-01-29T09:24:05","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=26856"},"modified":"2024-01-29T17:24:08","modified_gmt":"2024-01-29T09:24:08","slug":"%e8%8d%af%e7%89%a9%e5%88%86%e5%ad%90%e8%ae%be%e8%ae%a1part1%ef%bc%9a%e7%94%9f%e8%8d%af%e7%b1%bb%e5%b0%8f%e7%99%bd%e5%bf%85%e7%9c%8b%ef%bc%81%e4%b8%89%e5%88%86%e9%92%9f%e6%90%9e%e5%ae%9a%e9%85%8d","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=26856","title":{"rendered":"\u836f\u7269\u5206\u5b50\u8bbe\u8ba1part1\uff1a\u751f\u836f\u7c7b\u5c0f\u767d\u5fc5\u770b\uff01\u4e09\u5206\u949f\u641e\u5b9a\u914d\u4f53\u8bbe\u8ba1"},"content":{"rendered":"

\u8981\u8c08\u8bba\u5230\u751f\u7269\u4fe1\u606f\u5b66\u5c31\u4e1a\u6700\u70ed\u95e8\u7684\u9886\u57df\uff0c\u836f\u7269\u5206\u5b50\u8bbe\u8ba1\u7edd\u5bf9\u662f\u7ed5\u4e0d\u5f00\u7684\u4e00\u5927\u8bdd\u9898\u3002\u53ef\u80fd\u5f88\u591a\u751f\u4fe1\u7684\u5c0f\u4f19\u4f34\u4eec\u8ba4\u4e3a\u751f\u4fe1\u7684\u4e3b\u8981\u5de5\u4f5c\u9886\u57df\u5728\u5404\u79cd\u6570\u636e\u7684\u5904\u7406\u548c\u6316\u6398\u4e2d\uff0c\u4ece\u800c\u5bf9\u836f\u7269\u5206\u5b50\u8bbe\u8ba1\u8fd9\u4e00\u9886\u57df\u6709\u4e9b\u964c\u751f\u3002\u4ece\u4eca\u5929\u5f00\u59cb\uff0c\u5c0f\u679c\u5c31\u7ed9\u5927\u5bb6\u5e26\u6765\u4e00\u7cfb\u5217\u8be6\u7ec6\u7684\u836f\u7269\u5206\u5b50\u8bbe\u8ba1\u6d41\u7a0b\u6559\u5b66\u3002\u5e9f\u8bdd\u4e0d\u591a\u8bf4\uff0c\u6211\u4eec\u76f4\u63a5\u5f00\u59cb\u5427\uff01<\/p>\n

\u4ec0\u4e48\u662fDiscovery Studio\uff1f<\/h2>\n

Discovery Studio\u662f\u7531DNASTAR\u516c\u53f8\u5f00\u53d1\u7684\u4e00\u5957\u96c6\u6210\u7684\u8ba1\u7b97\u5316\u5b66\u548c\u5206\u5b50\u5efa\u6a21\u8f6f\u4ef6\u5957\u4ef6\u3002\u5b83\u88ab\u5e7f\u6cdb\u7528\u4e8e\u836f\u7269\u7814\u53d1\u3001\u86cb\u767d\u8d28\u7814\u7a76\u3001\u751f\u7269\u5206\u5b50\u6a21\u62df\u7b49\u9886\u57df\u3002<\/p>\n

Discovery Studio\u5177\u6709\u4e30\u5bcc\u7684\u529f\u80fd\u548c\u5de5\u5177\uff0c\u53ef\u7528\u4e8e\u836f\u7269\u8bbe\u8ba1\u3001\u865a\u62df\u7b5b\u9009\u3001\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u3001\u5206\u5b50\u52a8\u529b\u5b66\u6a21\u62df\u7b49\u4efb\u52a1\u3002<\/p>\n

<\/p>\n

\u4e0b\u9762\u5c0f\u679c\u7ed9\u5927\u5bb6\u5e26\u6765\u4e86Discovery Studio\u7684\u4e00\u4e9b\u5e38\u89c1\u7684\u529f\u80fd\u548c\u6a21\u5757\u4ecb\u7ecd\uff1a<\/p>\n

    \n
  1. LigandFit\uff08\u5206\u5b50\u5bf9\u63a5\u548c\u878d\u5408\uff09\uff1a\u8be5\u6a21\u5757\u53ef\u7528\u4e8e\u836f\u7269\u8bbe\u8ba1\u548c\u865a\u62df\u7b5b\u9009\u3002\u5b83\u5141\u8bb8\u7814\u7a76\u4eba\u5458\u5c06\u5c0f\u5206\u5b50\uff08\u836f\u7269\u5019\u9009\u7269\uff09\u4e0e\u86cb\u767d\u8d28\u9776\u70b9\u8fdb\u884c\u5bf9\u63a5\uff0c\u4ee5\u9884\u6d4b\u5b83\u4eec\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u548c\u7ed3\u5408\u80fd\u529b\u3002\u6b64\u5916\uff0cLigandFit\u8fd8\u652f\u6301\u5206\u5b50\u878d\u5408\u6280\u672f\uff0c\u7528\u4e8e\u5728\u5df2\u77e5\u914d\u4f53\u7684\u57fa\u7840\u4e0a\u751f\u6210\u65b0\u7684\u5206\u5b50\u3002<\/li>\n
  2. Sequence Viewer\uff08\u86cb\u767d\u8d28\u5e8f\u5217\u5206\u6790\u548c\u6bd4\u8f83\uff09\uff1a\u8be5\u6a21\u5757\u53ef\u7528\u4e8e\u5206\u6790\u548c\u6bd4\u8f83\u86cb\u767d\u8d28\u5e8f\u5217\u3002\u5b83\u63d0\u4f9b\u4e86\u591a\u4e2a\u5de5\u5177\uff0c\u5305\u62ec\u591a\u5e8f\u5217\u6bd4\u5bf9\u3001\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u548c\u529f\u80fd\u6ce8\u91ca\u3002\u901a\u8fc7Sequence Viewer\uff0c\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u786e\u5b9a\u86cb\u767d\u8d28\u5e8f\u5217\u4e4b\u95f4\u7684\u5171\u540c\u7279\u5f81\uff0c\u5e76\u63a8\u65ad\u5b83\u4eec\u4e4b\u95f4\u7684\u7ed3\u6784\u548c\u529f\u80fd\u5173\u7cfb\u3002<\/li>\n
  3. QSAR\u6a21\u5757\uff08\u5b9a\u91cf\u6784\u6548\u5173\u7cfb\uff09\uff1a\u8be5\u6a21\u5757\u4e3b\u8981\u7528\u4e8e\u6784\u5efa\u548c\u9884\u6d4b\u5b9a\u91cf\u6784\u6548\u5173\u7cfb\u6a21\u578b\u3002\u501f\u52a9QSAR\u6a21\u5757\uff0c\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u6839\u636e\u5206\u5b50\u7684\u7ed3\u6784\u548c\u6d3b\u6027\u6570\u636e\u8fdb\u884c\u6a21\u578b\u8bad\u7ec3\uff0c\u5e76\u4f7f\u7528\u6b64\u6a21\u578b\u9884\u6d4b\u65b0\u5316\u5408\u7269\u7684\u751f\u7269\u6d3b\u6027\u3002\u8fd9\u6709\u52a9\u4e8e\u52a0\u5feb\u836f\u7269\u7814\u53d1\u8fc7\u7a0b\uff0c\u7b5b\u9009\u51fa\u5177\u6709\u6f5c\u5728\u836f\u7269\u6d3b\u6027\u7684\u5316\u5408\u7269\u3002<\/li>\n
  4. CHARMm\uff08\u5206\u5b50\u52a8\u529b\u5b66\u6a21\u62df\uff09\uff1a\u8be5\u6a21\u5757\u53ef\u7528\u4e8e\u8fdb\u884c\u5206\u5b50\u52a8\u529b\u5b66\u6a21\u62df\uff0c\u6a21\u62df\u86cb\u767d\u8d28\u3001\u6838\u9178\u548c\u5c0f\u5206\u5b50\u5728\u6c34\u6eb6\u6db2\u4e2d\u7684\u52a8\u6001\u884c\u4e3a\u3002\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u901a\u8fc7CHARMm\u6a21\u5757\u4e86\u89e3\u5206\u5b50\u7684\u6784\u8c61\u6f14\u53d8\u3001\u76f8\u4e92\u4f5c\u7528\u4ee5\u53ca\u5176\u4e0e\u73af\u5883\u4e4b\u95f4\u7684\u5f71\u54cd\u3002\u8fd9\u5bf9\u4e8e\u7406\u89e3\u86cb\u767d\u8d28\u529f\u80fd\u548c\u836f\u7269-\u9776\u70b9\u76f8\u4e92\u4f5c\u7528\u673a\u5236\u81f3\u5173\u91cd\u8981\u3002<\/li>\n
  5. GCG\uff08\u751f\u7269\u5e8f\u5217\u5206\u6790\uff09\uff1aGCG\u6a21\u5757\u662f\u4e00\u4e2a\u5f3a\u5927\u7684\u5de5\u5177\uff0c\u7528\u4e8e\u5206\u6790\u548c\u5904\u7406\u751f\u7269\u5e8f\u5217\u6570\u636e\uff0c\u5305\u62ecDNA\u3001RNA\u548c\u86cb\u767d\u8d28\u5e8f\u5217\u3002\u5b83\u5305\u62ec\u591a\u4e2a\u8ba1\u7b97\u5de5\u5177\uff0c\u5982\u6bd4\u5bf9\u5de5\u5177\u3001\u641c\u7d22\u5de5\u5177\u548c\u6ce8\u91ca\u5de5\u5177\uff0c\u65b9\u4fbf\u4e86\u7814\u7a76\u4eba\u5458\u5bf9\u751f\u7269\u5e8f\u5217\u8fdb\u884c\u7cbe\u786e\u7684\u5206\u6790\u548c\u89e3\u91ca\u3002<\/li>\n<\/ol>\n

    \u901a\u8fc7\u4e0a\u9762\u51e0\u4e2a\u529f\u80fd\u7684\u4ecb\u7ecd\uff0c\u5c0f\u679c\u76f8\u4fe1\u5c0f\u4f19\u4f34\u4eec\u5df2\u7ecf\u521d\u6b65\u7406\u89e3\u4e86Discovery Studio\u7684\u5f3a\u5927\u4e4b\u5904\uff0c\u662f\u4e0d\u662f\u5df2\u7ecf\u8feb\u4e0d\u53ca\u5f85\u60f3\u77e5\u9053\u5177\u4f53\u5982\u4f55\u4f7f\u7528\u5b83\u4e86\u5462\uff1f\u73b0\u5728\u5c31\u8ddf\u4e0a\u5c0f\u679c\u7684\u8282\u594f\uff0c\u8fc5\u901f\u8d70\u8fd1\u5b83\uff01<\/p>\n

    \u7ed8\u5236\u5c0f\u5206\u5b50\u914d\u4f53<\/h2>\n

    <\/p>\n

    <\/p>\n

    <\/p>\n

    \u5982\u56fe\u6240\u793a\uff0c\u5c0f\u679c\u5148\u65b0\u5efa\u4e86\u4e00\u4e2a\u5c0f\u5206\u5b50\u7a97\u53e3\uff0c\u968f\u540e\u518dview->toolbar\u4e2d\u52fe\u9009sketching\u548cview\u4e24\u4e2a\u9009\u9879\uff0c\u8fd9\u6837\u6211\u4eec\u5c31\u53ef\u4ee5\u901a\u8fc7\u5de6\u4e0a\u89d2\u7684\u5de5\u5177\u680f\u6309\u6211\u4eec\u7684\u5fc3\u610f\u521b\u5efa\u5c0f\u5206\u5b50\u5566<\/p>\n

    <\/p>\n

    \u5982\u56fe\u5c0f\u679c\u6807\u51fa\u7684\u94c5\u7b14\u6309\u94ae\u53ef\u4ee5\u7528\u6765\u7ed8\u5236\u539f\u5b50\u548c\u5316\u5b66\u952e\uff0c\u5c0f\u679c\u5728\u8fd9\u91cc\u753b\u4e86\u4e00\u4e2a\u4e94\u5143\u73af\u4e3a\u4f8b\uff0c\u7ed9\u5927\u5bb6\u5c55\u793a\u4e00\u4e0b\u7ed8\u5236\u5c0f\u5206\u5b50\u57fa\u672c\u6846\u67b6\u7684\u65b9\u6cd5\u3002<\/p>\n

    <\/p>\n

    \u5982\u679c\u6211\u4eec\u60f3\u6539\u53d8\u5316\u5b66\u952e\uff0c\u53ef\u4ee5\u5148\u5728\u5de6\u4e0a\u89d2\u5207\u6362\u81f3\u7bad\u5934\u56fe\u6807\u6765\u9009\u62e9\u60f3\u8981\u6539\u53d8\u7684\u952e\uff0c\u968f\u540e\u9f20\u6807\u53f3\u51fb\u6253\u5f00\u83dc\u5355\uff0c\u5728bond\u83dc\u5355\u4e2d\u5bf9\u5316\u5b66\u952e\u7684\u7c7b\u578b\u8fdb\u884c\u8c03\u6574\u3002\u5728\u8fd9\u4e2a\u53f3\u952e\u62c9\u5f00\u7684\u83dc\u5355\u4e2d\u6211\u4eec\u8fd8\u53ef\u4ee5\u8fdb\u884c\u6539\u53d8\u67d0\u4e2a\u952e\u6216\u539f\u5b50\u663e\u793a\u989c\u8272\u6216\u6dfb\u52a0\u5907\u6ce8\u7b49\u7b49\u5176\u4ed6\u64cd\u4f5c\u3002<\/p>\n

    <\/p>\n

    \u6211\u4eec\u4e5f\u53ef\u4ee5\u9009\u4e2d\u67d0\u4e2a\u539f\u5b50\u6216\u5316\u5b66\u952e\u540e\uff0c\u70b9\u51fb\u4e0a\u65b9\u7684chemistry\u6309\u94ae\u62c9\u5f00\u83dc\u5355\uff0c\u5728\u8fd9\u91cc\u53ef\u4ee5\u8fdb\u884c\u6dfb\u52a0\u6c22\u539f\u5b50\u3001\u6539\u53d8\u9009\u4e2d\u539f\u5b50\u7684\u5143\u7d20\u7c7b\u578b\u3001\u6539\u53d8\u6742\u5316\u8f68\u9053\u7c7b\u578b\u3001\u6539\u53d8\u539f\u5b50\u5316\u5408\u4ef7\u3001\u6539\u53d8\u539f\u5b50\u6c27\u5316\u6001\u7b49\u7b49\u64cd\u4f5c\uff0c\u5c0f\u4f19\u4f34\u4eec\u53ef\u4ee5\u4e00\u4e00\u63a2\u7d22\u54e6~\u5c0f\u679c\u5728\u8fd9\u91cc\u628a\u9009\u4e2d\u7684C\u539f\u5b50\u66f4\u6539\u6210\u4e86N\u539f\u5b50\u3002<\/p>\n

    <\/p>\n

    \u5728\u5c0f\u4f19\u4f34\u4eec\u8c03\u6574\u5b8c\u81ea\u5df1\u521b\u5efa\u7684\u5c0f\u5206\u5b50\u540e\uff0c\u53ef\u4ee5\u5982\u56fe\u8fdb\u884c\u4f18\u5316\u4e09\u7ef4\u7ed3\u6784\u7684\u64cd\u4f5c\uff0c\u4e0b\u9762\u4e09\u5f20\u56fe\u5206\u522b\u662f\u4f18\u5316\u524d\uff0c\u4f18\u5316\u4e86\u9009\u4e2d\u7684N\u539f\u5b50\u540e\u4ee5\u53ca\u5bf9\u6574\u4f53\u5206\u5b50\u8fdb\u884c\u4f18\u5316\u540e\u7684\u7ed3\u679c\uff0c\u5c0f\u4f19\u4f34\u4eec\u53ef\u4ee5\u611f\u53d7\u4e00\u4e0b\u4f18\u5316\u524d\u540e\u662f\u4e0d\u662f\u786e\u5b9e\u6709\u6240\u4e0d\u540c\u5462~<\/p>\n

    <\/p>\n

    <\/p>\n

    <\/p>\n

    \u6211\u4eec\u4e5f\u53ef\u4ee5\u6309\u4f4f\u9f20\u6807\u53f3\u952e\u8fdb\u884c\u62d6\u52a8\u6765\u66f4\u6362\u89c2\u5bdf\u89d2\u5ea6\uff1a<\/p>\n

    <\/p>\n

    \u4ee5\u4e0a\u5c31\u662f\u6211\u4eec\u5728Discovery studio\u81ea\u5df1\u7ed8\u5236\u5c0f\u5206\u5b50\u914d\u4f53\u5e76\u8fdb\u884c\u8c03\u6574\u4f18\u5316\u7684\u8fc7\u7a0b\u5566\uff0c\u4f46\u662f\u5f88\u591a\u5c0f\u4f19\u4f34\u53ef\u80fd\u4f1a\u6bd4\u8f83\u719f\u6089\u5728\u522b\u7684\u5e73\u53f0\u6216\u8f6f\u4ef6\u8fdb\u884c\u7ed8\u5236\u5c0f\u5206\u5b50\uff0c\u6216\u8005\u76f4\u63a5\u5bfc\u5165\u73b0\u6709\u7684\u5c0f\u5206\u5b50\u6765\u8fdb\u884c\u64cd\u4f5c\uff0c\u90a3\u4e48\u4e0b\u9762\u5c0f\u679c\u5c31\u7ed9\u5927\u5bb6\u5c55\u793a\u4e00\u4e0b\u5982\u4f55\u5bf9\u5bfc\u5165\u7684\u6bd4\u8f83\u590d\u6742\u7684\u5c0f\u5206\u5b50\u8fdb\u884c\u64cd\u4f5c\u5427~<\/p>\n

    \u4f18\u5316\u5bfc\u5165\u7684\u914d\u4f53<\/h2>\n

    <\/p>\n

    \u5982\u56fe\u4ecefile->open\u53ef\u4ee5\u9009\u62e9\u6253\u5f00\u672c\u5730\u5c0f\u5206\u5b50\u6587\u4ef6<\/p>\n

    <\/p>\n

    \u5982\u56fe\u70b9\u51fbSmall Molecules>Prepare or Filter Ligands>Prepare Ligands\uff0c\u53ef\u4ee5\u6253\u5f00\u53c2\u6570\u8bbe\u7f6e\u9762\u677f\uff1b\u8bbe\u7f6eInput Ligands \u53c2\u6570\u4e3a’\u6587\u4ef6\u540d:All’\uff0c\u5373\u8868\u793a\u5bf9\u6240\u6709\u7684\u5c0f\u5206\u5b50\u8fdb\u884c\u5904\u7406\uff0c\u5176\u4f59\u53c2\u6570\u4e00\u822c\u9ed8\u8ba4\uff0c\u968f\u540e\u70b9\u51fbRUN\u8fd0\u884c\u3002<\/p>\n

    <\/p>\n

    \u8fd0\u884c\u7ed3\u675f\u540e\uff0c\u6211\u4eec\u53ef\u4ee5\u5728\u5f39\u51fa\u7684\u7a97\u53e3\u70b9\u51fbreport\u6765\u67e5\u770b\u5904\u7406\u4fe1\u606f\uff0c\u70b9\u51fb\u53f3\u4fa7\u7684view result\u540e\u5c31\u4f1a\u5f39\u51fa\u5de6\u4fa7\u7684\u754c\u9762\u89c2\u5bdf\u5904\u7406\u7ed3\u679c\u3002<\/p>\n

    <\/p>\n

    <\/p>\n

    \u5c0f\u4f19\u4f34\u4eec\u53ef\u80fd\u8fd8\u4e0d\u77e5\u9053\u8fd9\u4e00\u6b65\u64cd\u4f5c\u6709\u4ec0\u4e48\u4f5c\u7528\uff0c\u5c0f\u679c\u5728\u8fd9\u91cc\u7ed9\u5927\u5bb6\u89e3\u91ca\u4e00\u4e0b\uff1a\u901a\u8fc7”Prepare Ligands”\u529f\u80fd\uff0c\u53ef\u4ee5\u5bf9\u5c0f\u5206\u5b50\u8fdb\u884c\u4ee5\u4e0b\u64cd\u4f5c\uff1a<\/p>\n

      \n
    1. \u6e05\u6d01\u5316\u5408\u7269\u7ed3\u6784\uff1a\u4fee\u590d\u5c0f\u5206\u5b50\u4e2d\u7684\u7ed3\u6784\u95ee\u9898\uff0c\u5982\u4fee\u590d\u952e\u8fde\u63a5\u9519\u8bef\u3001\u586b\u8865\u7f3a\u5931\u539f\u5b50\u6216\u4fee\u6b63\u539f\u5b50\u7684\u5f62\u5f0f\u7535\u8377\u7b49\uff0c\u786e\u4fdd\u5206\u5b50\u7ed3\u6784\u7684\u6b63\u786e\u6027\u548c\u4e00\u81f4\u6027\u3002<\/li>\n
    2. \u6dfb\u52a0\u6c22\u539f\u5b50\uff1a\u4e3a\u4e86\u8fdb\u884c\u5206\u5b50\u529b\u573a\u8ba1\u7b97\u548c\u5176\u4ed6\u76f8\u5e94\u8ba1\u7b97\uff0c\u901a\u5e38\u9700\u8981\u5728\u5c0f\u5206\u5b50\u4e0a\u6dfb\u52a0\u9002\u5f53\u7684\u6c22\u539f\u5b50\u3002”Prepare Ligands”\u529f\u80fd\u53ef\u4ee5\u81ea\u52a8\u6dfb\u52a0\u6c22\u539f\u5b50\uff0c\u5e76\u8c03\u6574\u5176\u4f4d\u7f6e\uff0c\u4ee5\u4f7f\u5f97\u5206\u5b50\u80fd\u591f\u5728\u529b\u573a\u8ba1\u7b97\u4e2d\u5f97\u5230\u6b63\u786e\u7684\u63cf\u8ff0\u3002<\/li>\n
    3. \u79bb\u5b50\u5316\u5904\u7406\uff1a\u8be5\u529f\u80fd\u53ef\u4ee5\u5c06\u5c0f\u5206\u5b50\u7684\u79bb\u5b50\u72b6\u6001\u8fdb\u884c\u4fee\u6b63\uff0c\u5728\u6a21\u62df\u548c\u8ba1\u7b97\u8fc7\u7a0b\u4e2d\u8003\u8651\u6eb6\u5242\u548c\u79bb\u5b50\u7684\u6548\u5e94\u3002\u4f8b\u5982\uff0c\u53ef\u4ee5\u5bf9\u5c0f\u5206\u5b50\u8fdb\u884c\u8d28\u5b50\u5316\u6216\u53bb\u8d28\u5b50\u5316\u5904\u7406\u3002<\/li>\n
    4. \u80fd\u91cf\u6700\u5c0f\u5316\uff1a”Prepare Ligands”\u8fd8\u63d0\u4f9b\u4e86\u80fd\u91cf\u6700\u5c0f\u5316\u7684\u9009\u9879\uff0c\u4ee5\u8fdb\u4e00\u6b65\u4f18\u5316\u5c0f\u5206\u5b50\u7684\u6784\u8c61\u548c\u6027\u80fd\u3002\u901a\u8fc7\u80fd\u91cf\u6700\u5c0f\u5316\uff0c\u53ef\u4ee5\u5bfb\u627e\u5c0f\u5206\u5b50\u7684\u6700\u7a33\u5b9a\u6784\u8c61\uff0c\u8bc4\u4f30\u5176\u80fd\u91cf\u548c\u51e0\u4f55\u53c2\u6570\uff0c\u5e76\u4e3a\u540e\u7eed\u8ba1\u7b97\u63d0\u4f9b\u66f4\u53ef\u9760\u7684\u8d77\u70b9\u3002<\/li>\n<\/ol>\n

      \u6211\u4eec\u8fd8\u53ef\u4ee5\u901a\u8fc7Small Molecules|Minimize Ligands>Full Minimization\u6309\u94ae\u6267\u884c\u5c0f\u5206\u5b50\u7684\u5168\u80fd\u91cf\u6700\u5c0f\u5316\u8ba1\u7b97\uff0c\u8c03\u6574\u539f\u5b50\u7684\u4f4d\u7f6e\u548c\u952e\u957f\u3001\u89d2\u5ea6\u7b49\u53c2\u6570\uff0c\u5e2e\u52a9\u4f18\u5316\u5206\u5b50\u7684\u51e0\u4f55\u5f62\u72b6\u548c\u7a7a\u95f4\u6392\u5e03\uff0c\u5bfb\u627e\u5c0f\u5206\u5b50\u7684\u6700\u7a33\u5b9a\u6784\u8c61\u3002<\/p>\n

      <\/p>\n

      \u4f9d\u7136\u662f\u8bbe\u7f6eInput Ligands \u53c2\u6570\u4e3a’\u6587\u4ef6\u540d:All’\uff0c\u5176\u4f59\u53c2\u6570\u9ed8\u8ba4\uff0c\u968f\u540e\u70b9\u51fbRUN\u8fd0\u884c\u3002<\/p>\n

      \u8fd0\u884c\u7ed3\u675f\u540e\uff0c\u6211\u4eec\u53ef\u4ee5\u4ece\u8f6f\u4ef6\u6700\u4e0b\u65b9\u7684jobs\u4e2d\u627e\u5230\u6211\u4eec\u8fdb\u884c\u8fc7\u7684\u64cd\u4f5c\uff0c\u70b9\u51fb\u5373\u53ef\u6253\u5f00\u5df2\u7ecf\u5b8c\u6210\u8fc7\u7684\u64cd\u4f5c\u7ed3\u679c\u5566\u3002<\/p>\n

      <\/p>\n

      \u5c0f\u4f19\u4f34\u4eec\u53ef\u4ee5\u70b9\u51fb\u53f3\u4fa7\u7a97\u53e3\u6700\u4e0b\u9762\u7684view results\u6765\u66f4\u76f4\u89c2\u5730\u89c2\u770b\u7ed3\u679c\uff0c\u968f\u540e\u5c31\u4f1a\u5f39\u51fa\u5de6\u4fa7\u7ed3\u679c\u7a97\u53e3\uff0c\u6211\u4eec\u4e5f\u53ef\u4ee5\u8fdb\u884c\u62d6\u52a8\u7b49\u64cd\u4f5c\u6765\u89c2\u5bdf\u7ed3\u679c\u3002<\/p>\n

      <\/p>\n

      \u5230\u8fd9\u91cc\u4e3a\u6b62\uff0c\u914d\u4f53\u8bbe\u8ba1\u7684\u6700\u4e3b\u8981\u6d41\u7a0b\u5c31\u5df2\u7ecf\u5b8c\u6210\u5566\uff0c\u600e\u4e48\u6837\uff0c\u662f\u4e0d\u662f\u975e\u5e38\u7b80\u5355\u5462\uff1f\u7ec6\u5fc3\u7684\u5c0f\u4f19\u4f34\u53ef\u80fd\u5df2\u7ecf\u6ce8\u610f\u5230\uff0c\u5f53\u6211\u4eec\u628a\u9f20\u6807\u653e\u5230discovery studio\u7684\u5927\u591a\u6570\u6309\u94ae\u4e0a\u65f6\uff0c\u4f1a\u51fa\u73b0help\u6309\u94ae\uff0c\u5728\u4f7f\u7528\u8fc7\u7a0b\u4e2d\u5c0f\u4f19\u4f34\u4eec\u5982\u679c\u6709\u4ec0\u4e48\u7591\u95ee\u4e00\u5b9a\u8981\u591a\u67e5\u770bhelp\u54e6\uff0c\u53ea\u6709\u6df1\u5165\u4e86\u89e3\u539f\u7406\u548c\u5177\u4f53\u64cd\u4f5c\u6b65\u9aa4\u624d\u80fd\u5b8c\u6210\u5408\u683c\u7684\u836f\u7269\u8bbe\u8ba1\u3002<\/p>\n

      \u672c\u6b21\u7684\u5206\u4eab\u5c31\u5230\u8fd9\u91cc\u5566\uff0c\u5982\u679c\u5c0f\u4f19\u4f34\u4eec\u5e73\u65f6\u5728\u751f\u4fe1\u5206\u6790\u7684\u64cd\u4f5c\u8fc7\u7a0b\u4e2d\u9047\u5230\u56f0\u96be\uff0c\u6b22\u8fce\u5927\u5bb6\u4f7f\u7528\u5c0f\u679c\u5f00\u53d1\u7684\u751f\u4fe1\u5de5\u5177\u5e73\u53f0http:\/\/www.biocloudservice.com\/home.html<\/a>\u54e6\u3002\u4e0b\u4e00\u6b21\u7684\u5206\u4eab\u4e2d\u5c0f\u679c\u4f1a\u5411\u5927\u5bb6\u4ecb\u7ecd\u5982\u4f55\u5bf9\u86cb\u767d\u7ed3\u6784\u8fdb\u884c\u5904\u7406\uff0c\u5c0f\u4f19\u4f34\u4eec\u5343\u4e07\u4e0d\u8981\u9519\u8fc7\u54e6\uff0c\u5c0f\u679c\u671f\u5f85\u4e0e\u5927\u5bb6\u4e0b\u6b21\u518d\u89c1\uff0c\u62dc\u62dc~\u250f(\uff3e0\uff3e)\u251b<\/p>\n","protected":false},"excerpt":{"rendered":"

      \u8981\u8c08\u8bba\u5230\u751f\u7269\u4fe1\u606f\u5b66\u5c31\u4e1a\u6700\u70ed\u95e8\u7684\u9886\u57df\uff0c\u836f\u7269\u5206\u5b50\u8bbe\u8ba1\u7edd\u5bf9\u662f\u7ed5\u4e0d\u5f00\u7684\u4e00\u5927\u8bdd\u9898\u3002\u53ef\u80fd\u5f88\u591a\u751f\u4fe1\u7684\u5c0f\u4f19\u4f34\u4eec\u8ba4\u4e3a\u751f\u4fe1\u7684\u4e3b\u8981\u5de5 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/26856"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=26856"}],"version-history":[{"count":1,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/26856\/revisions"}],"predecessor-version":[{"id":26877,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/26856\/revisions\/26877"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=26856"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=26856"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=26856"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}