{"id":29795,"date":"2024-02-26T17:43:40","date_gmt":"2024-02-26T09:43:40","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=29795"},"modified":"2024-02-26T17:43:41","modified_gmt":"2024-02-26T09:43:41","slug":"%e6%9c%89%e6%88%91%e5%9c%a8%ef%bc%8c%e5%88%ab%e5%ae%b3%e6%80%95%ef%bc%81%e5%88%a9%e7%94%a8dnaman%e8%bf%9b%e8%a1%8c%e6%a0%b8%e9%85%b8%e6%af%94%e5%af%b9%e7%9a%84%e6%95%99%e7%a8%8b%e6%9d%a5%e5%95%a6","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=29795","title":{"rendered":"\u6709\u6211\u5728\uff0c\u522b\u5bb3\u6015\uff01\u5229\u7528DNAMAN\u8fdb\u884c\u6838\u9178\u6bd4\u5bf9\u7684\u6559\u7a0b\u6765\u5566~"},"content":{"rendered":"<p>\u6709\u6211\u5728\uff0c\u522b\u5bb3\u6015\uff01\u5229\u7528DNAMAN\u8fdb\u884c\u6838\u9178\u6bd4\u5bf9\u7684\u6559\u7a0b\u6765\u5566~<\/p>\n<p>DNAman\u662f\u4e00\u6b3e\u4e13\u4e1a\u7684\u5206\u5b50\u751f\u7269\u5b66\u8f6f\u4ef6\uff0c\u53ef\u4ee5\u7528\u4e8eDNA\u5e8f\u5217\u5206\u6790\u3001\u6bd4\u5bf9\u3001\u4fee\u526a\u3001\u91cd\u7ec4\u3001\u514b\u9686\u7b49\u64cd\u4f5c\u3002<\/p>\n<p>\u9996\u5148\u5bfc\u5165\u6bd4\u5bf9\u5e8f\u5217\uff0c\u5c0f\u679c\u8fd8\u662f\u7528\u4e0a\u6b21\u505a\u8fdb\u5316\u6811\u7528\u5230\u7684\u5e8f\u5217\uff1a\u901a\u8fc7NCBI<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/\">https:\/\/www.ncbi.nlm.nih.gov\/<\/a>\u83b7\u53d6\u5c3c\u7f57\u7f57\u975e\u9c7c(Oreochromis niloticus)\u3001\u6591\u70b9\u96c0\u9cdd(Lepisosteus oculatus)\u3001\u9752\u9cc9(Oryzias latipes)\u3001\u7ea2\u9ccd\u4e1c\u65b9\u9c80(Takifugu rubripes)\u3001\u6591\u9a6c\u9c7c(Danio rerio)\u3001\u5c0f\u9f20(Mus musculus)\u548c\u4eba(Homo sapiens)\u7684SOCS1\u57fa\u56e0fasta\u5e8f\u5217\u3002<\/p>\n<p>\u6253\u5f00DNAman9\u8f6f\u4ef6\uff0c\u9009\u62e9\u201cSequence\u201d\u83dc\u5355\u4e0b\u7684\u201cAlign sequences\u201d\u9009\u9879\u3002<\/p>\n<p>\u5728\u201cAlign sequences\u201d\u7a97\u53e3\u4e2d\uff0c\u70b9\u51fb\u201cMutiple Sequence Alignment\u201d\u6309\u94ae<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"373\" class=\"wp-image-29800\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-1.png?resize=640%2C373\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-1.png?w=755 755w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-1.png?resize=300%2C175 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-1.png?resize=600%2C350 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"546\" height=\"454\" class=\"wp-image-29801\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-2.png?resize=546%2C454\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-2.png?w=546 546w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-2.png?resize=300%2C249 300w\" sizes=\"(max-width: 546px) 100vw, 546px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u6ce8\u610f\u6700\u4e0b\u65b9\u5bfc\u5165\u7684\u5e8f\u5217\u662fDNA\u5e8f\u5217\u8fd8\u662f\u86cb\u767d\u5e8f\u5217\uff0c\u52fe\u9009\u76f8\u5e94\u7684\u5373\u53ef\uff0c\u70b9\u51fb\u53f3\u4fa7File\u5bfc\u5165fasta\u5e8f\u5217\uff0c\u4e0b\u4e00\u6b65<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"585\" height=\"512\" class=\"wp-image-29802\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-78.png?resize=585%2C512\" alt=\"\u56fe\u5f62\u7528\u6237\u754c\u9762, \u5e94\u7528\u7a0b\u5e8f\n\n\u63cf\u8ff0\u5df2\u81ea\u52a8\u751f\u6210\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-78.png?w=585 585w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-78.png?resize=300%2C263 300w\" sizes=\"(max-width: 585px) 100vw, 585px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u7ee7\u7eed\u4e0b\u4e00\u9875\uff0c\u5728\u8fd9\u4e2a\u754c\u9762\u4e00\u822c\u9ed8\u8ba4\u5373\u53ef<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"588\" height=\"520\" class=\"wp-image-29803\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-79.png?resize=588%2C520\" alt=\"\u56fe\u5f62\u7528\u6237\u754c\u9762\n\n\u63cf\u8ff0\u5df2\u81ea\u52a8\u751f\u6210\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-79.png?w=588 588w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-79.png?resize=300%2C265 300w\" sizes=\"(max-width: 588px) 100vw, 588px\" data-recalc-dims=\"1\" \/><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"606\" height=\"518\" class=\"wp-image-29804\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-5.png?resize=606%2C518\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-5.png?w=606 606w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-5.png?resize=300%2C256 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-5.png?resize=600%2C513 600w\" sizes=\"(max-width: 606px) 100vw, 606px\" data-recalc-dims=\"1\" \/><\/p>\n<p>* K-tuple\u7684\u5927\u5c0f\u4e00\u822c\u8bbe\u7f6e\u57282-6\u4e4b\u95f4\uff0c\u5177\u4f53\u53d6\u51b3\u4e8e\u5e8f\u5217\u7684\u957f\u5ea6\u548c\u53d8\u5f02\u6027\u3002\u901a\u5e38\u60c5\u51b5\u4e0b\uff0c\u8f83\u77ed\u7684K-tuple\u80fd\u591f\u66f4\u597d\u5730\u6355\u6349\u5e8f\u5217\u4e2d\u7684\u5c40\u90e8\u76f8\u4f3c\u6027\uff0c\u4f46\u53ef\u80fd\u4f1a\u5728\u6bd4\u5bf9\u8fc7\u7a0b\u4e2d\u4ea7\u751f\u8bef\u914d\u3002\u800c\u8f83\u957f\u7684K-tuple\u5219\u80fd\u591f\u66f4\u597d\u5730\u533a\u5206\u5e8f\u5217\u7684\u5dee\u5f02\uff0c\u4f46\u53ef\u80fd\u4f1a\u9519\u8fc7\u4e00\u4e9b\u76f8\u4f3c\u6027\u533a\u57df\u3002<\/p>\n<p>*Gap penalty\u548cgap extension penalty\uff1a\u8fd9\u4e24\u4e2a\u53c2\u6570\u63a7\u5236\u7a7a\u4f4d\u7684\u7f5a\u5206\uff0c\u5373\u7a7a\u4f4d\u51fa\u73b0\u7684\u60e9\u7f5a\u7a0b\u5ea6\u3002\u4e00\u822c\u60c5\u51b5\u4e0b\uff0cgap penalty\u7684\u503c\u5e94\u8be5\u6bd4gap extension 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https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-6.png?resize=768%2C587 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-6.png?resize=600%2C459 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" 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srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-7.png?w=1055 1055w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-7.png?resize=300%2C154 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-7.png?resize=1024%2C524 1024w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-7.png?resize=768%2C393 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word-image-29795-7.png?resize=600%2C307 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u5c0f\u679c\u94fe\u63a5\u5949\u4e0a\uff0c\u53ef\u4ee5\u6ee1\u8db3\u60a8\u591a\u6837\u5316\u7684\u751f\u4fe1\u5206\u6790\u9700\u6c42\uff1a<a href=\"http:\/\/www.biocloudservice.com\/home.html\">\u4e91\u751f\u4fe1 &#8211; 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