{"id":30019,"date":"2024-02-27T18:03:29","date_gmt":"2024-02-27T10:03:29","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=30019"},"modified":"2024-02-27T18:03:31","modified_gmt":"2024-02-27T10:03:31","slug":"%e4%bd%a0%e7%9a%84%e8%82%bf%e7%98%a4%e8%a7%a3%e5%af%86%e4%b8%93%e5%ae%b6%ef%bc%9ftimer%e6%95%99%e4%bd%a0%e6%b5%b8%e6%b6%a6%e5%85%8d%e7%96%ab%e7%bb%86%e8%83%9e%e5%88%86%e6%9e%90%ef%bc%81","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=30019","title":{"rendered":"\u4f60\u7684\u80bf\u7624\u89e3\u5bc6\u4e13\u5bb6\uff1fTIMER\u6559\u4f60\u6d78\u6da6\u514d\u75ab\u7ec6\u80de\u5206\u6790\uff01"},"content":{"rendered":"<p><strong>\u4f60\u7684\u80bf\u7624\u89e3\u5bc6\u4e13\u5bb6\uff1fTIMER\u6559\u4f60\u6d78\u6da6\u514d\u75ab\u7ec6\u80de\u5206\u6790\uff01<\/strong><\/p>\n<p>\u4eca\u5929\u5c0f\u679c\u5e26\u5927\u5bb6\u8ba4\u8bc6\u4e00\u4e2a\u4e13\u95e8\u7528\u6765\u5728\u514d\u75ab\u6d78\u6da6\u65b9\u9762\u505a\u5206\u6790\u7684\u7f51\u7ad9\uff0c\u90a3\u4e48\u5927\u5bb6\u548c\u6211\u4e00\u8d77\u6765\u770b\u770b\u5427\uff01<\/p>\n<ul>\n<li><strong>\u4ec0\u4e48\u662fTIMER<\/strong><\/li>\n<\/ul>\n<p>\u5728\u5b66\u4e60\u5982\u4f55\u4f7f\u7528\u4e4b\u524d\uff0c\u6211\u4eec\u5148\u6765\u7b80\u5355\u7684\u4e86\u89e3\u4e0bTIMER\u7f51\u7ad9\u662f\u505a\u4ec0\u4e48\u5de5\u4f5c\u7684\u5427\uff01<\/p>\n<p>TIMER\uff08Tumor Immune Estimation Resource\uff09\u662f\u4e00\u4e2a\u514d\u75ab\u6d78\u6da6\u5206\u6790\u7684\u7efc\u5408\u7f51\u7ad9\uff0c\u65e8\u5728\u5e2e\u52a9\u7814\u7a76\u4eba\u5458\u8bc4\u4f30\u80bf\u7624\u7ec4\u7ec7\u4e2d\u7684\u514d\u75ab\u6d78\u6da6\u60c5\u51b5\u3002\u8be5\u7f51\u7ad9\u63d0\u4f9b\u4e86\u4e00\u4e2a\u53ef\u89c6\u5316\u7684\u754c\u9762\uff0c\u5141\u8bb8\u7528\u6237\u8f93\u5165\u57fa\u56e0\u8868\u8fbe\u6570\u636e\u4ee5\u53ca\u5176\u4ed6\u76f8\u5173\u4fe1\u606f\uff0c\u7136\u540e\u4f7f\u7528\u4e0d\u540c\u7684\u7b97\u6cd5\u548c\u6a21\u578b\u6765\u4f30\u8ba1\u4e0d\u540c\u7c7b\u578b\u7684\u514d\u75ab\u7ec6\u80de\u6d78\u6da6\u60c5\u51b5\uff0c\u5305\u62ecT\u7ec6\u80de\u3001B\u7ec6\u80de\u3001\u5de8\u566c\u7ec6\u80de\u3001NK\u7ec6\u80de\u3001\u6811\u7a81\u72b6\u7ec6\u80de\u7b49\u7b49\uff0c\u5bf9\u4e8e\u80bf\u7624\u514d\u75ab\u5b66\u3001\u514d\u75ab\u6cbb\u7597\u548c\u836f\u7269\u7814\u53d1\u7b49\u65b9\u9762\u7684\u7814\u7a76\u90fd\u6709\u7740\u91cd\u8981\u7684\u5e94\u7528\u4ef7\u503c\u54e6\u3002<\/p>\n<ul>\n<li><strong>TIMER\u4e3b\u9875<\/strong><\/li>\n<\/ul>\n<p>\u901a\u8fc7<a href=\"https:\/\/cistrome.shinyapps.io\/timer\/\">https:\/\/cistrome.shinyapps.io\/timer\/<\/a>\uff0c\u5373\u53ef\u8fdb\u5165TIMER\u4e3b\u9875\u54e6\u3002\u8fdb\u5165\u4e3b\u9875\u540e\uff0c\u6211\u4eec\u53ef\u4ee5\u770b\u5230TIMER\u4e3b\u8981\u67097\u5927\u5728\u7ebf\u529f\u80fd\u6a21\u5757\uff0c\u5206\u522b\u662f\uff1aGene Module\uff0cSurvival\uff0cCorrelation\uff0cDiff. Expression\uff0cMutation\uff0cMethylation\uff0cSingle Gene\u3002 <img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"511\" class=\"wp-image-30020\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-94.png?resize=640%2C511\" alt=\"\u56fe\u5f62\u7528\u6237\u754c\u9762, \u6587\u672c, \u5e94\u7528\u7a0b\u5e8f\n\n\u63cf\u8ff0\u5df2\u81ea\u52a8\u751f\u6210\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-94.png?w=1500 1500w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-94.png?resize=300%2C240 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-94.png?resize=1024%2C818 1024w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-94.png?resize=768%2C613 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-94.png?resize=600%2C479 600w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-94.png?w=1280 1280w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u90a3\u4e48\u4eca\u5929\u5c0f\u679c\u5c06\u9488\u5bf9\u5176\u4e2d\u7684\u4e09\u4e2a\u6a21\u5757\u4e3a\u5927\u5bb6\u505a\u6f14\u793a\uff0c\u5927\u5bb6\u5feb\u548c\u5c0f\u679c\u4e00\u8d77\u5b66\u8d77\u6765\u5427\uff01<\/p>\n<ul>\n<li><strong>GENE<\/strong><\/li>\n<\/ul>\n<p>\u5728Gene Module\u4e2d\uff0c\u6211\u4eec\u53ef\u4ee5\u8f93\u5165\u611f\u5174\u8da3\u7684\u57fa\u56e0\u5217\u8868\uff0c\u5e76\u5c06\u5b83\u4eec\u5206\u7ec4\u4ee5\u8fdb\u884c\u8fdb\u4e00\u6b65\u7684\u5206\u6790\u3002\u7528\u6237\u53ef\u4ee5\u5728\u6570\u636e\u5e93\u4e2d\u9009\u62e9\u6216\u4e0a\u4f20\u4ed6\u4eec\u81ea\u5df1\u7684\u57fa\u56e0\u5217\u8868\u3002<\/p>\n<p><strong>\u4f7f\u7528\u65b9\u6cd5\uff1a<\/strong>\u5728\u201cGene Module\u201d\u9875\u9762\uff0c\u9009\u62e9\u6570\u636e\u5e93\u6216\u4e0a\u4f20\u81ea\u5df1\u7684\u57fa\u56e0\u5217\u8868\u3002\u7136\u540e\uff0c\u53ef\u4ee5\u9009\u62e9\u4e0d\u540c\u7684\u57fa\u56e0\u5206\u7ec4\u65b9\u6cd5\uff0c\u4f8b\u5982GO\u529f\u80fd\u6ce8\u91ca\u3001KEGG\u901a\u8def\u5206\u6790\u6216\u7528\u6237\u81ea\u5b9a\u4e49\u5206\u7ec4\u3002\u63a5\u4e0b\u6765\uff0c\u9009\u62e9\u5206\u6790\u53c2\u6570\uff0c\u6bd4\u5982\u5206\u6790\u9608\u503c\u548c\u5206\u7ec4\u65b9\u6cd5\uff0c\u6700\u540e\u70b9 <img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"321\" class=\"wp-image-30021\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word.png?resize=640%2C321\" alt=\"\u56fe\u5f62\u7528\u6237\u754c\u9762, \u5e94\u7528\u7a0b\u5e8f, Word\n\n\u63cf\u8ff0\u5df2\u81ea\u52a8\u751f\u6210\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word.png?w=1270 1270w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word.png?resize=300%2C150 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word.png?resize=1024%2C513 1024w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word.png?resize=768%2C385 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/word.png?resize=600%2C300 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/> \u51fb\u201cSubmit\u201d\u6309\u94ae\uff0c\u5373\u53ef\u5f97\u5230\u5206\u6790\u7ed3\u679c\u3002<\/p>\n<ul>\n<li><strong>Mutation<\/strong><\/li>\n<\/ul>\n<p>\u5728Mutation\u7ec4\u4ef6\u4e2d\uff0c\u6211\u4eec\u53ef\u4ee5\u8f93\u5165\u57fa\u56e0\u5217\u8868\u5e76\u9009\u62e9\u4e00\u4e2a\u764c\u75c7\u7c7b\u578b\uff0c\u4ee5\u67e5\u770b\u8fd9\u4e9b\u57fa\u56e0\u5728\u4e0d\u540c\u764c\u75c7\u6837\u672c\u4e2d\u7684\u53d8\u5f02\u60c5\u51b5\u3002\u8be5\u7ec4\u4ef6\u63d0\u4f9b\u4e86\u4e00\u79cd\u65b9\u4fbf\u7684\u65b9\u6cd5\u6765\u8bc4\u4f30\u57fa\u56e0\u5728\u764c\u75c7\u4e2d\u7684\u53d8\u5f02\u60c5\u51b5\u3002<\/p>\n<p><strong>\u4f7f\u7528\u65b9\u6cd5<\/strong>\uff1a\u5728\u201cMutation\u201d\u9875\u9762\uff0c\u9009\u62e9\u8981\u5206\u6790\u7684\u764c\u75c7\u7c7b\u578b\uff0c\u5e76\u8f93\u5165\u611f\u5174\u8da3\u7684\u57fa\u56e0\u5217\u8868\u3002\u7136\u540e\uff0c\u9009\u62e9\u6240\u9700\u7684\u6570\u636e\u5e93\u548c\u7a81\u53d8\u7c7b\u578b\uff0c\u4f8b\u5982\u9519\u4e49\u7a81\u53d8\u3001\u65e0\u4e49\u7a81\u53d8\u548c\u526a\u63a5\u4f4d\u70b9\u7a81\u53d8\u3002\u6700\u540e\uff0c\u70b9\u51fb\u201cSubmit\u201d\u6309\u94ae\uff0c\u5373\u53ef\u5f97\u5230\u57fa\u56e0\u5728\u4e0d\u540c\u764c\u75c7\u6837\u672c\u4e2d\u7684 <img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"650\" class=\"wp-image-30022\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-95.png?resize=640%2C650\" alt=\"\u56fe\u5f62\u7528\u6237\u754c\u9762\n\n\u63cf\u8ff0\u5df2\u81ea\u52a8\u751f\u6210\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-95.png?w=1156 1156w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-95.png?resize=295%2C300 295w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-95.png?resize=1008%2C1024 1008w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-95.png?resize=768%2C780 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-95.png?resize=600%2C609 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/> \u53d8\u5f02\u60c5\u51b5\u7ed3\u679c\u3002<\/p>\n<ul>\n<li><strong>Correlation<\/strong><\/li>\n<\/ul>\n<p>\u5728Correlation\u7ec4\u4ef6\u4e2d\uff0c\u6211\u4eec\u53ef\u4ee5\u8f93\u5165\u4e24\u4e2a\u57fa\u56e0\uff0c\u4ee5\u8bc4\u4f30\u5b83\u4eec\u4e4b\u95f4\u7684\u76f8\u5173\u6027\u3002\u8be5\u7ec4\u4ef6\u63d0\u4f9b\u4e86\u4e00\u79cd\u7b80\u5355\u800c\u6709\u7528\u7684\u5de5\u5177\uff0c\u7528\u4e8e\u8bc4\u4f30\u57fa\u56e0\u4e4b\u95f4\u7684\u5173\u7cfb\uff0c\u4ee5\u5e2e\u52a9\u53d1\u73b0\u6f5c\u5728\u7684\u751f\u7269\u5b66\u673a\u5236\u3002<\/p>\n<p><strong>\u4f7f\u7528\u65b9\u6cd5\uff1a<\/strong>\u5728\u201cCorrelation\u201d\u9875\u9762\uff0c\u8f93\u5165\u4e24\u4e2a\u611f\u5174\u8da3\u7684\u57fa\u56e0\u540d\u79f0\u3002\u7136\u540e\uff0c\u9009\u62e9\u8981\u4f7f\u7528\u7684\u6570\u636e\u5e93\u548c\u76f8\u5173\u6027\u65b9\u6cd5\uff0c\u5e76\u8bbe\u7f6e\u76f8\u5173\u6027\u5206\u6790\u53c2\u6570\u3002\u6700\u540e\uff0c\u70b9\u51fb\u201cSubmit\u201d\u6309\u94ae\uff0c\u5373\u53ef\u5f97\u5230\u57fa\u56e0\u4e4b\u95f4\u7684\u76f8\u5173\u6027\u7ed3\u679c\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"812\" class=\"wp-image-30023\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-96.png?resize=640%2C812\" alt=\"\u56fe\u5f62\u7528\u6237\u754c\u9762, \u56fe\u8868\n\n\u63cf\u8ff0\u5df2\u81ea\u52a8\u751f\u6210\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-96.png?w=907 907w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-96.png?resize=236%2C300 236w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-96.png?resize=807%2C1024 807w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-96.png?resize=768%2C975 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-96.png?resize=600%2C761 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u600e\u4e48\u6837\uff0c\u4eca\u5929\u7684\u5728\u7ebf\u5de5\u5177\u4f60\u5b66\u7684\u600e\u4e48\u6837\u5462\uff1f\u66f4\u591a\u5b66\u4e60\u8d44\u6e90\u8bf7\u5927\u5bb6\u79fb\u6b65\u5c0f\u679c\u4e13\u5c5e\u4e91\u751f\u4fe1\u5e73\u53f0\u641c\u7d22\u66f4\u591a\u8d44\u6e90\u54e6\uff01<\/p>\n<p>\u5c0f\u679c\u4e13\u5c5e\u4e91\u751f\u4fe1\u5e73\u53f0\uff1a<a href=\"http:\/\/www.biocloudservice.com\/home.html\">\u4e91\u751f\u4fe1 \u00a0&#8211; \u5b66\u751f\u7269\u4fe1\u606f\u5b66 (biocloudservice.com)<\/a><\/p>\n<p>\u4e91\u751f\u4fe1\u5e73\u53f0\u4e5f\u6709\u514d\u75ab\u4e13\u7248\u7684\u5b66\u4e60\u6a21\u5757\u54e6\uff0c\u5feb\u6765\u627e\u5230\u4f60\u60f3\u5b66\u4e60\u7684\u4e13\u5c5e\u6a21\u5757\u5427\uff01<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"239\" class=\"wp-image-30024\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-97.png?resize=640%2C239\" alt=\"\u8868\u683c\n\n\u63cf\u8ff0\u5df2\u81ea\u52a8\u751f\u6210\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-97.png?w=895 895w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-97.png?resize=300%2C112 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-97.png?resize=768%2C287 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/02\/unnamed-file-97.png?resize=600%2C224 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4f60\u7684\u80bf\u7624\u89e3\u5bc6\u4e13\u5bb6\uff1fTIMER\u6559\u4f60\u6d78\u6da6\u514d\u75ab\u7ec6\u80de\u5206\u6790\uff01 \u4eca\u5929\u5c0f\u679c\u5e26\u5927\u5bb6\u8ba4\u8bc6\u4e00\u4e2a\u4e13\u95e8\u7528\u6765\u5728\u514d\u75ab\u6d78\u6da6\u65b9\u9762\u505a\u5206\u6790\u7684\u7f51\u7ad9\uff0c [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/30019"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=30019"}],"version-history":[{"count":1,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/30019\/revisions"}],"predecessor-version":[{"id":30025,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/30019\/revisions\/30025"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=30019"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=30019"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=30019"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}