{"id":37311,"date":"2024-04-24T09:55:25","date_gmt":"2024-04-24T01:55:25","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=37311"},"modified":"2024-04-25T09:58:14","modified_gmt":"2024-04-25T01:58:14","slug":"37311","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=37311","title":{"rendered":"\u88ab\u5938\u7206\u7684\u673a\u5668\u5b66\u4e60\u5728\u6b64\uff01\u5ddd\u5927\u534e\u897f\u533b\u674e\u8273\u56e2\u961f\u6559\u4f60\u673a\u5668\u5b66\u4e60\u5982\u4f55\u7834\u5708\uff1a\u642d\u4e0a\u591a\u7ec4\u5b66\u8f7b\u53d67+\u7eaf\u751f\u4fe1\uff0c\u201c\u6551\u547d\u7a3b\u8349\u201d\u53ef\u4ee5\u4e00\u5b66\uff01"},"content":{"rendered":"<p><a id=\"post-37311-OLE_LINK23\"><\/a><\/p>\n<p><a id=\"post-37311-OLE_LINK16\"><\/a> 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id=\"post-37311-OLE_LINK10\"><\/a> 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id=\"post-37311-OLE_LINK20\"><\/a><strong>Cox\u56de\u5f52\u6a21\u578b<\/strong>\u7b49\u673a\u5668\u5b66\u4e60\u65b9\u6cd5\u5bf9\u9884\u540e\u7279\u5f81\u8fdb\u884c\u8fdb\u4e00\u6b65\u7684\u8bad\u7ec3\u548c\u68c0\u9a8c\uff0c\u6700\u540e\u6784\u5efa\u76f8\u5173\u6a21\u578b\uff1b<\/li>\n<li>\u6700\u540e\uff0c\u4f5c\u8005\u5206\u6790\u4e86<strong>\u9884\u540e\u98ce\u9669\u4e0e\u514d\u75ab\u6d78\u6da6\u3001\u80bf\u7624\u5fae\u73af\u5883\u3001\u514d\u75ab\u7ec6\u80de\u548c\u514d\u75ab\u6cbb\u7597\u4e4b\u95f4<\/strong>\u7684\u76f8\u5173\u6027\u548c\u5dee\u5f02\u3002\u5bf9\u673a\u5668\u5b66\u4e60\u611f\u5174\u8da3\u5e76\u4e14\u60f3\u8981\u53d1\u8868\u9ad8\u5206SCI\u7684\u5c0f\u4f19\u4f34\u4eec\u4e5f\u53ef\u4ee5\u501f\u9274\u4e00\u4e0b\u672c\u6587\u7684\u7814\u7a76\u601d\u8def\u54e6~\uff08ps\uff1a\u673a\u5668\u5b66\u4e60\u518d\u8054\u5408\u764c\u75c7\u7814\u7a76\u65e0\u7591\u662f\u53d1\u6587\u5229\u5668\uff0c\u4f46\u5e38\u89c4\u5957\u8def\u60f3\u8981\u53d1\u4e2a\u597d\u6587\u7ae0\u53ef\u8c13\u75f4\u4eba\u8bf4\u68a6\uff0c\u90a3\u5bf9\u673a\u5668\u5b66\u4e60\u611f\u5174\u8da3\u4f46\u4e0d\u77e5\u9053\u600e\u4e48\u521b\u65b0\u7684\u5c0f\u4f19\u4f34\u53ef\u4ee5\u6765\u627e\u5c0f\u4e91\u54e6\uff01\u8fd9\u91cc\u6709\u9ad8\u5206\u6613\u590d\u73b0\u7684\u521b\u65b0\u601d\u8def\uff0c\u5c0f\u4f19\u4f34\u4eec\u8d76\u7d27\u6765\u516c\u4f17\u53f7\u540e\u53f0\u627e\u6211\u5662\uff01\uff09<a id=\"post-37311-OLE_LINK21\"><\/a><a id=\"post-37311-OLE_LINK11\"><\/a><\/li>\n<\/ol>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-36511 aligncenter\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/2.jpg?resize=298%2C300\" alt=\"\" width=\"298\" height=\"300\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/2.jpg?resize=298%2C300 298w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/2.jpg?resize=150%2C150 150w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/2.jpg?resize=100%2C100 100w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/2.jpg?w=568 568w\" sizes=\"(max-width: 298px) 100vw, 298px\" data-recalc-dims=\"1\" \/><\/p>\n<p><img decoding=\"async\" class=\"wp-image-37312\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37311-1.png?w=640\" data-recalc-dims=\"1\" \/><\/p>\n<ul>\n<li>\u9898\u76ee\uff1a\u57fa\u4e8e\u673a\u5668\u5b66\u4e60\u7684\u809d\u764c\u9884\u540e\u6a21\u578b\u7684\u7cbe\u7ec6\u6cbb\u7597\u65b9\u6848<\/li>\n<li>\u6742\u5fd7\uff1a<a id=\"post-37311-OLE_LINK36\"><\/a><em>Computers in Biology and Medicine <\/em><\/li>\n<li>\u5f71\u54cd\u56e0\u5b50\uff1aIF=7.7<\/li>\n<li>\u53d1\u8868\u65f6\u95f4\uff1a2024\u5e741\u6708<\/li>\n<\/ul>\n<p><strong>\u7814\u7a76\u80cc\u666f<\/strong><\/p>\n<p>\u809d\u7ec6\u80de\u764c\uff08LIHC\uff09\u662f\u5371\u5bb3\u6700\u5927\u7684\u80bf\u7624\u4e4b\u4e00\uff0c\u5728\u672a\u6765\u51e0\u5e74\u5185\uff0c\u6bcf\u5e74\u7684\u75c5\u4f8b\u6570\u5c06\u7a81\u7834100\u4e07\u4f8b\uff0c\u56e0\u6b64\uff0c\u6539\u5584\u8fdb\u5c55\u548c\u9884\u540e\u4e0d\u4ec5\u662f\u4e00\u4e2a\u73b0\u5b9e\u7684\u95ee\u9898\uff0c\u4e5f\u662f\u4e00\u4e2a\u52bf\u5728\u5fc5\u884c\u7684\u95ee\u9898\u3002\u8d8a\u6765\u8d8a\u591a\u7684\u8bc1\u636e\u8868\u660e\uff0c\u4e0e\u4f20\u7edf\u7684\u5316\u7597\u6216\u653e\u7597\u76f8\u6bd4\uff0c\u9776\u5411\u6cbb\u7597\u662f\u6cbb\u7597\u764c\u75c7\u7684\u6709\u6548\u7b56\u7565\uff0c\u5bfb\u627e\u5408\u7406\u7684\u9776\u70b9\u6709\u52a9\u4e8e\u836f\u7269\u7684\u5f00\u53d1\u548c\u4e34\u5e8a\u7684\u836f\u7269\u9009\u62e9\u4e0e\u7ec4\u5408\u3002\u708e\u75c7\u662f\u4e00\u79cd\u91cd\u8981\u7684\u751f\u7406\u548c\u514d\u75ab\u53cd\u5e94\uff0c\u76f8\u5173\u5b66\u8005\u62a5\u9053\u80bf\u7624\u7684\u53d1\u5c55\u4e0e\u708e\u75c7\u8fc7\u7a0b\u4e4b\u95f4\u5b58\u5728\u7740\u590d\u6742\u7684\u4e32\u6270\uff0c\u4e00\u65b9\u9762\u4fc3\u708e\u56e0\u5b50\u548c\u7ec6\u80de\u56e0\u5b50\u80fd\u591f\u589e\u5f3a\u673a\u4f53\u7684\u6297\u80bf\u7624\u4f5c\u7528\uff0c\u4f46\u53e6\u4e00\u65b9\u9762\u963b\u65ad\u708e\u75c7\u4fe1\u53f7\u901a\u8def\u53cd\u800c\u53ef\u4ee5\u63d0\u9ad8\u764c\u75c7\u6cbb\u7597\u6548\u679c\u3002\u56e0\u6b64\uff0c\u5728\u8fd9\u9879\u7814\u7a76\u4e2d\uff0c<a id=\"post-37311-OLE_LINK19\"><\/a>\u4f5c\u8005\u65e8\u5728\u63a2\u7d22\u4e0e\u708e\u75c7\u5bc6\u5207\u76f8\u5173\u7684\u9884\u540e\u7279\u5f81\uff0c\u5e76\u5229\u7528\u751f\u7269\u4fe1\u606f\u5b66\u6280\u672f\u548cLIHC\u57fa\u56e0\u8868\u8fbe\u5927\u6570\u636e\uff0c\u6784\u5efa\u66f4\u7cbe\u786e\u7684\u9884\u540e\u6a21\u578b\uff0c\u8fdb\u800c\u4e3aLIHC\u60a3\u8005\u6cbb\u7597\u63d0\u4f9b\u65b0\u7684\u53c2\u8003\u3002<\/p>\n<p><strong>\u6570\u636e\u6765\u6e90<\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td>\u6570\u636e\u5e93<\/td>\n<td>\u8be6\u7ec6\u4fe1\u606f<\/td>\n<\/tr>\n<tr>\n<td>TCGA\u3001GTEx\u3001HPA\u53caGEO\u6570\u636e\u5e93<\/td>\n<td>LIHC\u7684RNA\u6d4b\u5e8f\u8868\u8fbe\u8c31\u3001IHC\u53ca\u5355\u7ec6\u80de\u6570\u636e<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>\u7814\u7a76\u601d\u8def<\/strong><\/p>\n<p>\u9996\u5148\uff0c\u4f5c\u8005\u4eceTCGA\u548cGTEx\u6570\u636e\u95e8\u6237\u7f51\u7ad9\u4e0b\u8f7dLIHC\u7684RNA\u6d4b\u5e8f\u8868\u8fbe\u8c31\u3001\u7a81\u53d8\u6570\u636e\u548c\u76f8\u5e94\u7684\u4e34\u5e8a\u4fe1\u606f\uff0c\u800cLIHC\u7684\u514d\u75ab\u7ec4\u5316\uff08IHC\uff09\u67d3\u8272\u56fe\u50cf\u6765\u81eaHuman Protein Atlas\uff08HPA\uff09Visualization\u6570\u636e\u5e93\uff0c\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u5206\u6790\u6765\u81eaGEO\u6570\u636e\u5e93\u4e2d\u7684GSE156337\u3002\u4f5c\u8005\u5148\u662f\u89c2\u5bdf\u4e86\u80bf\u7624\u4e0e\u90bb\u8fd1\u6b63\u5e38\u7ec4\u7ec7\u4e2d10\u4e2a\u5173\u952e\u708e\u75c7\u76f8\u5173\u57fa\u56e0\u7684\u57fa\u56e0\u8868\u8fbe\u6c34\u5e73\u5e76\u7edf\u8ba1\u4e86\u5176\u62f7\u8d1d\u6570\u53d8\u5f02\uff08CNV\uff09\u7684\u9891\u7387\u53ca\u5176\u5728\u67d3\u8272\u4f53\u4e0a\u7684\u4f4d\u7f6e\u3002\u4e3a\u4e86\u7814\u7a76\u4e0a\u8ff0\u708e\u75c7\u76f8\u5173\u57fa\u56e0\u662f\u5426\u4e0eLIHC\u7684\u9884\u540e\u76f8\u5173\uff0c\u4f5c\u8005\u6839\u636e\u8fd9\u4e9b\u57fa\u56e0\u7684\u8868\u8fbe\u6c34\u5e73\u548c\u901a\u8fc7\u5185\u90e8\u4e00\u81f4\u6027\u548c\u805a\u7c7b\u6548\u5e94\u5206\u6790\uff0c\u5c06LIHC\u75c5\u4f8b\u5206\u6210\u4e24\u4e2a\u4e3b\u8981\u805a\u7c7b\uff0c\u5206\u522b\u8fdb\u884c\u4e86\u751f\u5b58\u5206\u6790\u3001\u57fa\u56e0\u96c6\u53d8\u5f02\u5206\u6790\u53ca\u57fa\u56e0\u96c6\u5bcc\u96c6\u5206\u6790\u663e\u793a\u3002\u63a5\u7740\uff0c\u4f5c\u8005\u5c06\u9664\u6b63\u5e38\u7ec4\u5916\u7684LIHC\u63091:1\u7684\u6bd4\u4f8b\u968f\u673a\u5206\u4e3a\u8bad\u7ec3\u96c6\u548c\u9a8c\u8bc1\u96c6\uff0c\u5bf9\u8bad\u7ec3\u96c6\u8fdb\u884c\u5355\u53d8\u91cfCox\u56de\u5f52\u5206\u6790\uff0c\u7b5b\u9009\u4e0e\u9884\u540e\u7279\u5f81\u56e0\u7d20\u76f8\u5173\u7684\u4fe1\u606f\uff0c\u5c06\u5176\u5e94\u7528\u4e8eLASSO\u56de\u5f52\u5e76\u8fdb\u884c10\u500d\u4ea4\u53c9\u9a8c\u8bc1\uff1b\u5728\u591a\u53d8\u91cfCox\u56de\u5f52\u6a21\u578b\u5bf9\u9884\u540e\u7279\u5f81\u8fdb\u884c\u8fdb\u4e00\u6b65\u7684\u8bad\u7ec3\u548c\u68c0\u9a8c\uff0c\u6700\u540e\u7b5b\u90093\u4e2a\u57fa\u56e0\u548c2\u4e2alncRNAs\u8fdb\u884c\u9884\u540e\u98ce\u9669\u8bc4\u4f30\uff0c\u5728\u6b64\u57fa\u7840\u4e0a\uff0c\u4f5c\u8005\u6784\u5efa\u4e86\u9884\u540e\u98ce\u9669\u8bc4\u4f30\u6a21\u578b\u5373Inf-PR\u6a21\u578b\u3002\u968f\u540e\u4f5c\u8005\u5206\u6790\u4e86\u9884\u540e\u98ce\u9669\u4e0e\u514d\u75ab\u6d78\u6da6\u3001\u80bf\u7624\u5fae\u73af\u5883\u3001\u514d\u75ab\u7ec6\u80de\u548c\u514d\u75ab\u6cbb\u7597\u4e4b\u95f4\u7684\u76f8\u5173\u6027\u548c\u5dee\u5f02\u3002<\/p>\n<p><strong>\u4e3b\u8981\u7ed3\u679c<\/strong><\/p>\n<p><a id=\"post-37311-OLE_LINK5\"><\/a><strong>\u4e00.LIHC\u4e2d\u708e\u75c7\u76f8\u5173\u57fa\u56e0\u7684\u7279\u5f81<\/strong><\/p>\n<p>\u9996\u5148\uff0c\u4f5c\u8005\u4eceTCGA\u548cGTEx\u6570\u636e\u95e8\u6237\u7f51\u7ad9\u4e0b\u8f7dLIHC\u7684RNA\u6d4b\u5e8f\u8868\u8fbe\u8c31\u3001\u7a81\u53d8\u6570\u636e\u548c\u76f8\u5e94\u7684\u4e34\u5e8a\u4fe1\u606f\uff0c\u800cLIHC\u7684\u514d\u75ab\u7ec4\u5316\uff08IHC\uff09\u67d3\u8272\u56fe\u50cf\u6765\u81eaHuman Protein Atlas\uff08HPA\uff09Visualization\u6570\u636e\u5e93\uff0c\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u5206\u6790\u6765\u81eaGEO\u6570\u636e\u5e93\u4e2d\u7684GSE156337\u3002\u4f5c\u8005\u89c2\u5bdf\u4e86\u80bf\u7624\u4e0e\u90bb\u8fd1\u6b63\u5e38\u7ec4\u7ec7\u4e2d10\u4e2a\u5173\u952e\u708e\u75c7\u76f8\u5173\u57fa\u56e0\u7684\u57fa\u56e0\u8868\u8fbe\u6c34\u5e73\uff0c\u5bf9\u6bd4\u5206\u6790\u53d1\u73b0\u5176\u4e2d8\u4e2a\u57fa\u56e0\u7684\u8868\u8fbe\u6c34\u5e73\u6709\u663e\u8457\u5dee\u5f02\uff08\u56fe1A\uff09\uff0c\u5176\u4e2d\uff0cEIF2AK2\u3001GSDMD\u3001IL18\u3001CASP1\u3001PYCARD\u3001NLRP3\u548cNLRC4\u5728\u80bf\u7624\u7ec4\u7ec7\u4e2d\u7684\u8868\u8fbe\u6c34\u5e73\u663e\u8457\u9ad8\u4e8e\u6b63\u5e38\u7ec4\u7ec7\uff0c\u800cNLRP1\u7684\u8868\u8fbe\u6c34\u5e73\u5219\u663e\u8457\u4f4e\u4e8e\u6b63\u5e38\u7ec4\u7ec7\uff1b\u540c\u65f6\uff0c\u4f5c\u8005\u4eceHPA\u6570\u636e\u5e93\u4e2d\u8fdb\u884c\u514d\u75ab\u7ec4\u5316\u5206\u6790\uff08\u56fe1B\uff09\u548c\u5355\u7ec6\u80de\u6d4b\u5e8f\u5206\u6790\uff08\u56fe1C\u548cD\uff09\uff0c\u540c\u6837\u8bc1\u5b9e\u4e86\u4e0a\u8ff08\u4e2a\u57fa\u56e0\u7684\u8868\u8fbe\u6c34\u5e73\u5728\u80bf\u7624\u7ec4\u7ec7\u548c\u6b63\u5e38\u7ec4\u7ec7\u4e2d\u5b58\u5728\u5dee\u5f02\uff0c\u4f46\u5728\u4e24\u7ec4\u4e2d\u4e0a\u8ff0\u57fa\u56e0\u5747\u6ca1\u6709\u660e\u663e\u7684\u9057\u4f20\u6539\u53d8\u5bcc\u96c6\u533a\uff0c\u7ffb\u8bd1\u540e\u4fee\u9970\u7684\u7c7b\u578b\u548c\u4f4d\u70b9\u4e3b\u8981\u4e3a\u78f7\u9178\u5316\u4fee\u9970\uff08\u56fe2A\uff09\u3002NLRP3\u5177\u6709\u6700\u9ad8\u7684\u80bf\u7624\u7a81\u53d8\u8d1f\u8377\u53d1\u751f\u7387\uff08TMB\uff09\uff0c\u5176\u9519\u4e49\u7a81\u53d8\u7684\u9891\u7387\u7ea6\u4e3a2%\uff08\u56fe2B\uff09\uff1b\u6b64\u5916\uff0c\u4f5c\u8005\u7edf\u8ba1\u4e86\u62f7\u8d1d\u6570\u53d8\u5f02\uff08CNV\uff09\u7684\u9891\u7387\u53ca\u5176\u5728\u67d3\u8272\u4f53\u4e0a\u7684\u4f4d\u7f6e\uff0c\u7ed3\u679c\u663e\u793a10\u4e2a\u57fa\u56e0\u5747\u4fdd\u6301\u4e00\u5b9a\u7684CNV\u9891\u7387\uff0c\u5176\u4e2d6\u4e2a\u57fa\u56e0\u51fa\u73b0\u6269\u589e\uff0c\u53e6\u59164\u4e2a\u57fa\u56e0\u51fa\u73b0\u7f3a\u5931\uff08\u56fe2C\uff09\u3002<\/p>\n<p><img decoding=\"async\" class=\"wp-image-37313\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/3-3-12.png?w=640\" alt=\"\u7b2c3\u9875-3\" data-recalc-dims=\"1\" \/><\/p>\n<p><a id=\"post-37311-OLE_LINK3\"><\/a> \u56fe1 LIHC\u4e2d\u708e\u75c7\u76f8\u5173\u57fa\u56e0\u5206\u6790<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"371\" class=\"wp-image-37314\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-5-12.png?resize=640%2C371\" alt=\"\u7b2c4\u9875-5\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-5-12.png?w=2155 2155w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-5-12.png?resize=300%2C174 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-5-12.png?resize=1024%2C593 1024w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-5-12.png?resize=768%2C445 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-5-12.png?resize=1536%2C890 1536w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-5-12.png?resize=2048%2C1186 2048w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-5-12.png?resize=600%2C347 600w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-5-12.png?w=1280 1280w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-5-12.png?w=1920 1920w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u56fe1 LIHC\u4e2d\u76f8\u5173\u57fa\u56e0\u7684\u7a81\u53d8\u72b6\u6001\u53ca\u7ffb\u8bd1\u540e\u4fee\u9970<\/p>\n<p><strong>\u4e8c.<\/strong><a id=\"post-37311-OLE_LINK7\"><\/a><strong>\u4e9a\u7fa4\u805a\u7c7b\u5206\u6790<\/strong><\/p>\n<p>\u4e3a\u4e86\u7814\u7a76\u4e0a\u8ff0\u708e\u75c7\u76f8\u5173\u57fa\u56e0\u662f\u5426\u4e0eLIHC\u7684\u9884\u540e\u76f8\u5173\uff0c\u4f5c\u8005\u6839\u636e\u8fd9\u4e9b\u57fa\u56e0\u7684\u8868\u8fbe\u6c34\u5e73\u548c\u901a\u8fc7\u5185\u90e8\u4e00\u81f4\u6027\u548c\u805a\u7c7b\u6548\u5e94\u5206\u6790\uff0c\u5c06LIHC\u75c5\u4f8b\u5206\u6210\u4e24\u4e2a\u4e3b\u8981\u805a\u7c7b\uff08\u56fe3A\uff09\u3002\u751f\u5b58\u5206\u6790\u663e\u793a\uff0c\u708e\u75c7\u672c\u8eab\u4e0e\u75be\u75c5\u7684\u9884\u540e\u6ca1\u6709\u76f4\u63a5\u5173\u7cfb\uff08\u56fe3B\uff09\uff1b\u63a5\u7740\uff0c\u4f5c\u8005\u5bf9\u4e24\u4e2a\u7c07\u4e4b\u95f4\u7684KEGG\u901a\u8def\u8fdb\u884c\u4e86\u57fa\u56e0\u96c6\u53d8\u5f02\u5206\u6790\u3002\u7ed3\u679c\u663e\u793a\uff0cA\u96c6\u7fa4\u4e3b\u8981\u5bcc\u96c6\u4e8e\u4ee3\u8c22\u9014\u5f84\u5982\u7f2c\u6c28\u9178\u3001\u4eae\u6c28\u9178\u548c\u5f02\u4eae\u6c28\u9178\u7684\u964d\u89e3\uff1b\u800cB\u96c6\u7fa4\u4e3b\u8981\u6fc0\u6d3b\u75be\u75c5\u76f8\u5173\u9014\u5f84\uff08\u56fe3C\uff09\uff1b\u57fa\u56e0\u96c6\u5bcc\u96c6\u5206\u6790\u663e\u793a\uff0c\u514d\u75ab\u7ec6\u80de\u7684\u4e30\u5ea6\u5982\u6d3b\u5316CD4<sup>+<\/sup> T\u7ec6\u80de\u3001\u6d3b\u5316CD8<sup>+ <\/sup>T\u7ec6\u80de\u3001\u6d3b\u5316\u6811\u7a81\u72b6\u7ec6\u80de\u548cCD56dim NK\u7ec6\u80de\u5728\u96c6\u7fa4B\u4e2d\u6bd4\u5728\u96c6\u7fa4A\u4e2d\u5177\u6709\u7edf\u8ba1\u5b66\u610f\u4e49\uff0c\u4f46\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u76f8\u53cd\uff08\u56fe3D\uff09\u3002\u7efc\u4e0a\u6240\u8ff0\uff0c\u708e\u75c7\u5e76\u4e0d\u80fd\u76f4\u63a5\u53cd\u6620LIHC\u7684\u9884\u540e\uff0c\u4f46\u5b83\u4e0e\u4fe1\u53f7\u901a\u8def\u7684\u53d8\u5f02\u548c\u514d\u75ab\u72b6\u6001\u660e\u663e\u76f8\u5173\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"349\" class=\"wp-image-37315\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-4-12.png?resize=640%2C349\" alt=\"\u7b2c4\u9875-4\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-4-12.png?w=2155 2155w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-4-12.png?resize=300%2C164 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-4-12.png?resize=1024%2C558 1024w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-4-12.png?resize=768%2C419 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-4-12.png?resize=1536%2C837 1536w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-4-12.png?resize=2048%2C1117 2048w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-4-12.png?resize=600%2C327 600w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-4-12.png?w=1280 1280w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/4-4-12.png?w=1920 1920w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p><a id=\"post-37311-OLE_LINK18\"><\/a><a id=\"post-37311-OLE_LINK9\"><\/a> \u56fe3 \u4e9a\u7fa4\u805a\u7c7b\u5206\u6790<\/p>\n<p><a id=\"post-37311-OLE_LINK14\"><\/a><strong>\u4e09.<\/strong><a id=\"post-37311-OLE_LINK8\"><\/a><a id=\"post-37311-OLE_LINK1\"><\/a><a id=\"post-37311-OLE_LINK2\"><\/a><strong>\u57fa\u4e8e\u5dee\u5206\u805a\u7c7b\u7684\u9884\u6d4b\u6a21\u578b\u6784\u5efa<\/strong><\/p>\n<p><a id=\"post-37311-OLE_LINK25\"><\/a> 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decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"552\" class=\"wp-image-37316\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/5-6-12.png?resize=640%2C552\" alt=\"\u7b2c5\u9875-6\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/5-6-12.png?w=1835 1835w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/5-6-12.png?resize=300%2C259 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/5-6-12.png?resize=1024%2C884 1024w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/5-6-12.png?resize=768%2C663 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/5-6-12.png?resize=1536%2C1326 1536w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/5-6-12.png?resize=600%2C518 600w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/5-6-12.png?w=1280 1280w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p><a id=\"post-37311-OLE_LINK12\"><\/a> \u56fe4 \u57fa\u4e8e\u5dee\u5206\u805a\u7c7b\u7684\u9884\u6d4b\u6a21\u578b\u6784\u5efa<\/p>\n<p><a id=\"post-37311-OLE_LINK4\"><\/a><strong>\u56db.<\/strong><a id=\"post-37311-OLE_LINK15\"><\/a><strong>\u9884\u540e\u98ce\u9669\u80cc\u540e\u7684\u514d\u75ab\u7279\u6027<\/strong><\/p>\n<p>\u4e3a\u4e86\u63ed\u793a\u9884\u540e\u6a21\u578b\u7684\u6f5c\u5728\u514d\u75ab\u666f\u89c2\u7279\u5f81\uff0c\u4f5c\u8005\u5206\u6790\u4e86\u9884\u540e\u98ce\u9669\u4e0e\u514d\u75ab\u6d78\u6da6\u3001\u80bf\u7624\u5fae\u73af\u5883\u3001\u514d\u75ab\u7ec6\u80de\u548c\u514d\u75ab\u6cbb\u7597\u4e4b\u95f4\u7684\u76f8\u5173\u6027\u548c\u5dee\u5f02\u3002CIBERSORT\u5206\u6790\u663e\u793a\uff0c\u9884\u540e\u98ce\u9669\u4e0e\u5de8\u566c\u7ec6\u80deM0 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decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"808\" class=\"wp-image-37317\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/6-7-12.png?resize=640%2C808\" alt=\"\u7b2c6\u9875-7\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/6-7-12.png?w=2046 2046w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/6-7-12.png?resize=238%2C300 238w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/6-7-12.png?resize=811%2C1024 811w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/6-7-12.png?resize=768%2C970 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/6-7-12.png?resize=1217%2C1536 1217w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/6-7-12.png?resize=1622%2C2048 1622w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/6-7-12.png?resize=600%2C757 600w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/6-7-12.png?w=1280 1280w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/6-7-12.png?w=1920 1920w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p><a id=\"post-37311-OLE_LINK13\"><\/a> \u56fe5 \u9884\u540e\u98ce\u9669\u80cc\u540e\u7684\u514d\u75ab\u7279\u6027<\/p>\n<p><strong>\u4e94.\u6839\u636eLIHC\u7684\u9884\u540e\u6a21\u578b\u9009\u62e9\u6cbb\u7597\u836f\u7269<\/strong><\/p>\n<p><a id=\"post-37311-OLE_LINK6\"><\/a> 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