{"id":37331,"date":"2024-04-24T10:09:27","date_gmt":"2024-04-24T02:09:27","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=37331"},"modified":"2024-04-25T13:43:24","modified_gmt":"2024-04-25T05:43:24","slug":"37331","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=37331","title":{"rendered":"\u5965\u79d8\u89e3\u7801\uff1a\u79d1\u5b66\u5bb6\u63ed\u793a\u7ec6\u80de\u7ec8\u6781\u5f52\u5bbf\u7684\u60ca\u4eba\u771f\u76f8\uff0c\u76f8\u5173SCI\u7684\u53d1\u8868\u4e5f\u5982\u96e8\u540e\u6625\u7b0b"},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone  wp-image-36510\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/1.jpg?resize=640%2C136\" alt=\"\" width=\"640\" height=\"136\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/1.jpg?resize=300%2C64 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/1.jpg?resize=768%2C163 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/1.jpg?resize=600%2C128 600w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/1.jpg?w=940 940w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" 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decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-36511 aligncenter\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/2.jpg?resize=298%2C300\" alt=\"\" width=\"298\" height=\"300\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/2.jpg?resize=298%2C300 298w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/2.jpg?resize=150%2C150 150w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/2.jpg?resize=100%2C100 100w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/2.jpg?w=568 568w\" sizes=\"(max-width: 298px) 100vw, 298px\" data-recalc-dims=\"1\" \/><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"200\" class=\"wp-image-37332\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-1.png?resize=640%2C200\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-1.png?w=731 731w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-1.png?resize=300%2C94 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-1.png?resize=600%2C188 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<ul>\n<li>\u9898\u76ee\uff1a\u673a\u5668\u5b66\u4e60\u63ed\u793a\u80ba\u817a\u764c\u9884\u540e\u548c\u6cbb\u7597\u4e2d\u4e0d\u540c\u7684\u7ec6\u80de\u6b7b\u4ea1\u6a21\u5f0f<\/li>\n<li>\u6742\u5fd7\uff1anpj | precision oncology<\/li>\n<li>\u5f71\u54cd\u56e0\u5b50\uff1aIF=7.9<\/li>\n<li>\u53d1\u8868\u65f6\u95f4\uff1a2024\u5e742\u6708<\/li>\n<\/ul>\n<p><strong>\u7814\u7a76\u80cc\u666f<\/strong><\/p>\n<p>\u764c\u7ec6\u80de\u7684\u751f\u957f\u3001\u8f6c\u79fb\u548c\u8010\u836f\u7ed9\u80ba\u817a\u764c(LUAD)\u7684\u6cbb\u7597\u5e26\u6765\u4e86\u5de8\u5927\u7684\u6311\u6218\u3002\u7136\u800c\uff0c\u76ee\u524d\u5c1a\u7f3a\u4e4f\u80fd\u591f\u51c6\u786e\u9884\u6d4b\u60a3\u8005\u9884\u540e\u5e76\u6307\u5bfc\u9776\u5411\u6cbb\u7597\u9009\u62e9\u7684\u6700\u4f73\u9884\u6d4b\u6a21\u578b\u3002\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea1(PCD)\u901a\u8def\u5728\u591a\u79cd\u80bf\u7624\u7684\u53d1\u751f\u3001\u53d1\u5c55\u4e2d\u8d77\u5173\u952e\u4f5c\u7528\uff0c\u4e3a\u80ba\u817a\u764c\u60a3\u8005\u63d0\u4f9b\u4e86\u6f5c\u5728\u7684\u9884\u540e\u6307\u6807\u548c\u836f\u7269\u654f\u611f\u6027\u6807\u5fd7\u7269\u3002<\/p>\n<p><strong>\u6570\u636e\u6765\u6e90<\/strong><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"565\" height=\"461\" class=\"wp-image-37333\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-2.png?resize=565%2C461\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-2.png?w=565 565w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-2.png?resize=300%2C245 300w\" sizes=\"(max-width: 565px) 100vw, 565px\" data-recalc-dims=\"1\" 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decoding=\"async\" loading=\"lazy\" width=\"500\" height=\"718\" class=\"wp-image-37334\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-3.png?resize=500%2C718\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-3.png?w=500 500w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-3.png?resize=209%2C300 209w\" sizes=\"(max-width: 500px) 100vw, 500px\" data-recalc-dims=\"1\" \/><\/p>\n<p><strong>\u4e3b\u8981\u7ed3\u679c<\/strong><\/p>\n<p><strong>LUAD\u60a3\u8005\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea1\u57fa\u56e0\u7684\u53d8\u5f02\u666f\u89c2<\/strong><\/p>\n<p>\u5bf9TCGA-LUAD\u548c 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https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-4.png?resize=222%2C300 222w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-4.png?resize=759%2C1024 759w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-4.png?resize=768%2C1036 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-4.png?resize=1139%2C1536 1139w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-4.png?resize=600%2C809 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u56fe1 PCD-DEGs\u7a81\u53d8\u666f\u89c2<\/p>\n<p><strong>\u901a\u8fc7\u57fa\u4e8e\u673a\u5668\u5b66\u4e60\u6784\u5efaLUAD\u60a3\u8005\u7684\u9884\u540e\u57fa\u56e0\u6a21\u578b<\/strong><\/p>\n<p>\u57fa\u4e8eTCGA-LUAD\u4f7f\u7528LOOCV\uff08\u7559\u4e00\u6cd5\u4ea4\u53c9\u9a8c\u8bc1\uff09\u62df\u540870\u79cd\u9884\u6d4b\u6a21\u578b\u5e76\u8ba1\u7b97\u6bcf\u4e2a\u6a21\u578b\u7684C\u6307\u6570\uff0c\u9009\u62e9C\u6307\u6570\u6700\u9ad8\u7684\u4e24\u4e2a\u6a21\u578b\u7ec4\u5408\uff08Lasso\u548cRSF+Lasso\uff09\u7b5b\u9009\u57fa\u56e0\uff0c\u5f97\u523035\u4e2a\u57fa\u56e0\u3002\u5c06\u8fd935\u4e2a\u57fa\u56e0\u4e0eLasso\u56de\u5f52\u5206\u6790\u786e\u5b9a\u7684\u57fa\u56e0\u53d6\u4ea4\u96c6\u5f97\u523010\u4e2a\u57fa\u56e0\u3002\u57fa\u4e8e\u8fd910\u4e2a\u57fa\u56e0\u6784\u5efa\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea1\u6307\u6570\uff08PCDI\uff09\uff0c\u5e76\u6839\u636ePCDI\u5c06\u60a3\u8005\u5206\u4e3a\u9ad8\u4f4e\u98ce\u9669\u7ec4\uff0c\u7ed3\u679c\u663e\u793a\u9ad8PCDI\u7ec4\u9884\u540e\u8f83\u5dee\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"673\" class=\"wp-image-37336\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-5.png?resize=640%2C673\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-5.png?w=1309 1309w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-5.png?resize=285%2C300 285w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-5.png?resize=974%2C1024 974w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-5.png?resize=768%2C807 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37331-5.png?resize=600%2C631 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u56fe2 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