{"id":37978,"date":"2024-04-28T10:20:17","date_gmt":"2024-04-28T02:20:17","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=37978"},"modified":"2024-04-28T10:20:20","modified_gmt":"2024-04-28T02:20:20","slug":"%e5%a2%99%e8%a3%82%e5%ae%89%e5%88%a9%ef%bc%81%e5%9c%a8%e7%ba%bf%e6%95%b0%e6%8d%ae%e5%ba%93%e5%ba%94%e7%94%a8%e5%88%b0%e6%9e%81%e8%87%b4%e7%9a%84%e5%8d%95%e5%9f%ba%e5%9b%a0%e6%b3%9b%e7%99%8c%e5%88%86","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=37978","title":{"rendered":"\u5899\u88c2\u5b89\u5229\uff01\u5728\u7ebf\u6570\u636e\u5e93\u5e94\u7528\u5230\u6781\u81f4\u7684\u5355\u57fa\u56e0\u6cdb\u764c\u5206\u6790\u601d\u8def\uff0c\u5e72\u6e7f\u7ed3\u5408\u62ff\u4e0b7\u5206+\uff0c\u751f\u4fe1\u5c0f\u767d\u95ed\u773c\u5165\uff0c\u6362\u4e2a\u57fa\u56e0\u5373\u590d\u73b0\uff01"},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone  wp-image-36510\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/1.jpg?resize=640%2C137\" alt=\"\" width=\"640\" height=\"137\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/1.jpg?resize=300%2C64 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/1.jpg?resize=768%2C163 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/1.jpg?resize=600%2C128 600w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/1.jpg?w=940 940w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u5355\u57fa\u56e0\u751f\u4fe1\u5206\u6790\u4f5c\u4e3a\u751f\u4fe1\u601d\u8def\u5927\u519b\u4e2d\u7684\u57fa\u77f3\uff0c\u4e00\u76f4\u662f\u65b0\u624b\u6751\u9009\u624b\u7684\u9996\u9009~ ~<\/p>\n<p>\u56e0\u4e3a\u5b83\u5360\u636e\u201c\u5929\u65f6\u5730\u5229\u4eba\u548c\u201d\uff0c\u5206\u6790\u601d\u8def\u6bd4\u8f83\u7b80\u5355\u3001\u65b0\u624b\u5c0f\u767d\u597d\u4e0a\u624b\uff1b\u8fdb\u53ef\u653b\uff08\u751f\u4fe1\u5355\u72ec\u6210\u6587\uff09\u9000\u53ef\u5b88\uff08\u751f\u4fe1\u7ed3\u5408\u6e7f\u5b9e\u9a8c\u5f62\u6210\u5927\u8bfe\u9898\uff09\uff1b\u601d\u8def\u5e94\u7528\u5e7f\u6cdb\uff08\u4e0d\u9650\u75be\u75c5\u3001\u4e0d\u9650\u76ee\u7684\uff09\uff1b\u8f7b\u8f7b\u677e\u677e\u5b9e\u73b0\u7701\u94b1\u63d0\u5206\u5927\u8ba1\uff01<strong>\uff08ps\uff1a\u5c0f\u4e91\u524d\u9762\u5df2\u7ecf\u5206\u4eab\u8fc7\u4e86\u591a\u79cd\u5355\u57fa\u56e0\u5206\u6790\u601d\u8def\uff0c\u611f\u5174\u8da3\u7684\u5c0f\u4f19\u4f34\u6b22\u8fce\u8fdb\u5165\u516c\u4f17\u53f7\u641c\u7d22\u6216\u70b9\u51fb\u6587\u672b\u94fe\u63a5\u89c2\u770b\u54e6\uff09<\/strong><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"190\" height=\"190\" class=\"wp-image-37979\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-1.png?resize=190%2C190\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-1.png?w=190 190w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-1.png?resize=150%2C150 150w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-1.png?resize=100%2C100 100w\" sizes=\"(max-width: 190px) 100vw, 190px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u867d\u7136\u5355\u57fa\u56e0\u5206\u6790\u5df2\u7ecf\u662f\u6bd4\u8f83\u7b80\u5355\u57fa\u7840\u7684\u601d\u8def\u4e86\uff0c\u4f46\u6709\u4e9b\u5206\u6790\u8fd8\u662f\u4f7f\u7528R\u5305\uff0c\u8fd9\u5bf9\u4e8e\u521a\u5165\u95e8\u7684\u670b\u53cb\u8fd8\u662f\u6709\u4e9b\u96be\u5ea6\u7684\uff0c\u5c0f\u4e91\u8fd9\u6b21\u518d\u7ed9\u670b\u53cb\u4eec\u51cf\u51cf\u8d1f\uff0c\u63a8\u8350\u4e00\u4e2a<strong>\u628a\u5728\u7ebf\u6570\u636e\u5e93\u5e94\u7528\u5230\u6781\u81f4\u7684\u601d\u8def\uff0c\u53ea\u6709\u5f88\u5c0f\u90e8\u5206\u4f7f\u7528R\u5305\uff0c\u5927\u591a\u6570\u5206\u6790\u90fd\u53ef\u4ee5\u7528\u6570\u636e\u5e93\u89e3\u51b3\uff0c<\/strong>\u662f\u4e0d\u662f\u63a8\u8350\u5230\u4f60\u5fc3\u574e\u91cc\u4e86\u5462\uff1f<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"240\" height=\"240\" class=\"wp-image-37980\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-2.jpeg?resize=240%2C240\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-2.jpeg?w=240 240w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-2.jpeg?resize=150%2C150 150w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-2.jpeg?resize=100%2C100 100w\" sizes=\"(max-width: 240px) 100vw, 240px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u5177\u4f53\u600e\u4e48\u64cd\u4f5c\uff1f\u4e0b\u9762\u4e0a\u5b9e\u4f8b\uff01\u8fd9\u4e2a7\u5206+\u7684\u6587\u7ae0\u662f\u5229\u7528\u591a\u79cd\u5728\u7ebf\u6570\u636e\u5e93\u8fdb\u884c\u5355\u57fa\u56e0\u6cdb\u764c\u5206\u6790\uff0c\u518d\u8054\u5408\u5355\u7ec6\u80de\u6570\u636e\u5206\u6790\u548c\u9a8c\u8bc1\u5b9e\u9a8c\uff0c\u5206\u6790\u64cd\u4f5c\u5f88\u7b80\u5355\uff0c\u4f46\u5185\u5bb9\u975e\u5e38\u4e30\u5bcc\uff0c\u540c\u65f6\u521b\u65b0\u6027\u4e5f\u4e0d\u9519\uff0c\u8d85\u7ea7\u9002\u5408\u751f\u4fe1\u5165\u95e8\u9009\u624b\uff01\u624b\u63e1\u76ee\u6807\u57fa\u56e0\u60f3\u7528\u751f\u4fe1\u7701\u94b1\u63d0\u5206\u7684\u670b\u53cb\u5feb\u4e0a\u8f66\uff0c\u9ad8\u5206\u6587\u7ae0\u5728\u5411\u4f60\u62db\u624b\u5566\uff01<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-medium wp-image-36511 aligncenter\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/2.jpg?resize=298%2C300\" alt=\"\" width=\"298\" height=\"300\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/2.jpg?resize=298%2C300 298w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/2.jpg?resize=150%2C150 150w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/2.jpg?resize=100%2C100 100w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/2.jpg?w=568 568w\" sizes=\"(max-width: 298px) 100vw, 298px\" data-recalc-dims=\"1\" \/><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"152\" class=\"wp-image-37981\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-3.png?resize=640%2C152\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-3.png?w=700 700w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-3.png?resize=300%2C71 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-3.png?resize=600%2C142 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<ul>\n<li>\u9898\u76ee\uff1aCENPO\u7684\u6cdb\u764c\u666f\u89c2\u53ca\u5176\u5728LUAD\u4e2d\u7684\u6f5c\u5728\u673a\u5236<\/li>\n<li>\u6742\u5fd7\uff1a<em>Respir Res<\/em><\/li>\n<li>\u5f71\u54cd\u56e0\u5b50\uff1aIF=7.162<\/li>\n<li>\u53d1\u8868\u65f6\u95f4\uff1a2023\u5e744\u6708<\/li>\n<\/ul>\n<p><strong>\u7814\u7a76\u80cc\u666f<\/strong><\/p>\n<p>\u7740\u4e1d\u7c92\u86cb\u767dO (CENPO)\u662f\u4e00\u79cd\u65b0\u53d1\u73b0\u7684\u7ec4\u6210\u578b\u7740\u4e1d\u7c92\u86cb\u767d\uff0c\u4e0e\u7ec6\u80de\u6b7b\u4ea1\u6709\u5173\u3002\u7136\u800c\uff0c CENPO\u7684\u8868\u8fbe\u4e0e\u4eba\u7c7b\u764c\u75c7\u6216\u514d\u75ab\u6d78\u6da6\u6b7b\u4ea1\u76f8\u5173\u6027\u4ecd\u4e0d\u6e05\u695a\u3002\u56e0\u6b64\uff0c\u4f5c\u8005\u8bc4\u4f30\u4e86CENPO\u5728\u6cdb\u764c\u4e2d\u7684\u529f\u80fd\uff0c\u5e76\u901a\u8fc7\u4f53\u5916\u548c\u4f53\u5185\u5b9e\u9a8c\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u4e86\u5176\u5728\u80ba\u817a\u764c(LUAD)\u4e2d\u7684\u7ed3\u679c\u3002<\/p>\n<p><strong>\u6570\u636e\u6765\u6e90<\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td><strong>\u6570\u636e\u96c6\/\u961f\u5217<\/strong><\/td>\n<td><strong>\u6570\u636e\u5e93<\/strong><\/td>\n<td><strong>\u6570\u636e\u7c7b\u578b<\/strong><\/td>\n<td><strong>\u6837\u672c\u4fe1\u606f<\/strong><\/td>\n<\/tr>\n<tr>\n<td>\u6cdb\u764c\u961f\u5217<\/td>\n<td>Sangerbox + TCGA<\/td>\n<td>RNA-seq\u6570\u636e+\u4f53\u7ec6\u80de\u7a81\u53d8\u6570\u636e+\u4e34\u5e8a\u4fe1\u606f<\/td>\n<td>Sangerbox \u5305\u542b34\u79cd\u4eba\u7c7b\u764c\u75c7\u6570\u636e\uff0cTCGA\u5305\u542b33\u79cd\u764c\u75c7\u6570\u636e<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>\u7814\u7a76\u601d\u8def<\/strong><\/p>\n<p>\u9996\u5148\u5229\u7528Sangerbox\u548cTCGA\u6570\u636e\u5e93\u8bc4\u4f30\u4e0d\u540c\u4eba\u7c7b\u764c\u75c7\u7c7b\u578b\u4e2d\u7684CENPO\u8868\u8fbe\u6c34\u5e73\u3002\u968f\u540e\u5bf9CENPO\u4f5c\u4e3a\u6cdb\u764c\u8bca\u65ad\u548c\u9884\u540e\u751f\u7269\u6807\u5fd7\u7269\u7684\u6f5c\u5728\u4f5c\u7528\u8fdb\u884c\u4e86\u8bc4\u4f30\u3002\u4f7f\u7528cBioPortal\u6570\u636e\u5e93\u5206\u6790CENPO\u7a81\u53d8\uff0c\u4f7f\u7528LinkedOmics\u548cCancerSEA\u6570\u636e\u5e93\u5206\u6790\u5176\u529f\u80fd\u3002\u5229\u7528TIMER2\u548cTISIDB\u7f51\u7ad9\u5206\u6790CENPO\u4e0e\u514d\u75ab\u6d78\u6da6\u7684\u76f8\u5173\u6027\u3002\u901a\u8fc7TCGA\u6570\u636e\u5e93\u548c\u4e34\u5e8a\u6837\u672cIHC\u67d3\u8272\u9a8c\u8bc1CENPO\u5728LUAD\u4e2d\u7684\u8868\u8fbe\u6c34\u5e73\u3002\u4f7f\u7528Targetscan\u3001miRWalk\u3001miRDB\u3001miRabel\u3001LncBase\u6570\u636e\u5e93\u548cCytoscape\u5de5\u5177\u9274\u5b9a\u8c03\u8282\u8868\u8fbe\u7684miRNAs\u548clncRNAs\uff0c\u5e76\u6784\u5efaceRNA\u7f51\u7edc\u3002\u968f\u540e\uff0c\u5728\u4f53\u5916\u548c\u4f53\u5185\u5b9e\u9a8c\u4e2d\uff0c\u8fdb\u884c\u529f\u80fd\u4e27\u5931\u6d4b\u5b9a\u4ee5\u9274\u5b9aCENPO\u5bf9LUAD\u7684\u5f71\u54cd\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"1011\" class=\"wp-image-37982\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-4.png?resize=640%2C1011\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-4.png?w=785 785w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-4.png?resize=190%2C300 190w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-4.png?resize=648%2C1024 648w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-4.png?resize=768%2C1213 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-4.png?resize=600%2C948 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p><strong>\u4e3b\u8981\u7ed3\u679c<\/strong><\/p>\n<p><strong>1. CENPO\u5728\u6cdb\u764c\u4e2d\u7684\u8868\u8fbe\u5206\u6790<\/strong><\/p>\n<p>\u9996\u5148\u5728GTEx\u6570\u636e\u5e93\u4e2d\u5206\u6790CENPO\u5728\u5404\u79cd\u7ec4\u7ec7\u548c\u7ec6\u80de\u4e2d\u7684\u8868\u8fbe\u6c34\u5e73\uff08\u56fe1B\uff09\uff0c\u7136\u540e\u4f7f\u7528TIMER 2.0\u6570\u636e\u5e93\u5206\u6790\u4e86TCGA\u6570\u636e\u96c6\u4e2d\u7684CENPO\u8868\u8fbe\uff08\u56fe1C\uff09\uff0c\u5e76\u5728GEPIA2\u7f51\u7ad9\u4e0a\u5206\u6790\u4e86CENPO\u548c\u6cdb\u764c\u5206\u671f\u4e4b\u95f4\u7684\u76f8\u5173\u6027\uff08\u56fe1E\uff09\uff0c\u4ee5\u4e0a\u7ed3\u679c\u5747\u663e\u793aCENPO\u5728\u5927\u591a\u6570\u764c\u75c7\u4e2d\u4e0a\u8c03\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"215\" class=\"wp-image-37983\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-5.png?resize=640%2C215\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-5.png?w=1231 1231w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-5.png?resize=300%2C101 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-5.png?resize=1024%2C344 1024w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-5.png?resize=768%2C258 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-5.png?resize=600%2C201 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"366\" class=\"wp-image-37984\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-6.png?resize=640%2C366\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-6.png?w=730 730w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-6.png?resize=300%2C171 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-6.png?resize=600%2C343 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"621\" height=\"349\" class=\"wp-image-37985\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-7.png?resize=621%2C349\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-7.png?w=621 621w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-7.png?resize=300%2C169 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-7.png?resize=600%2C337 600w\" sizes=\"(max-width: 621px) 100vw, 621px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"278\" height=\"337\" class=\"wp-image-37986\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-8.png?resize=278%2C337\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-8.png?w=278 278w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-8.png?resize=247%2C300 247w\" sizes=\"(max-width: 278px) 100vw, 278px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u56fe1 CENPO\u5728\u6cdb\u764c\u4e2d\u7684\u8868\u8fbe\u5206\u6790<\/p>\n<p><strong>2. CENPO\u5728\u6cdb\u764c\u8bca\u65ad\u548c\u9884\u540e\u4e2d\u7684\u4f5c\u7528\u8bc4\u4f30<\/strong><\/p>\n<p>\u57fa\u4e8eTCGA\u6cdb\u764c\u961f\u5217\uff0c\u7528ROC\u66f2\u7ebf\u8bc4\u4f30CENPO\u5728\u764c\u75c7\u8bca\u65ad\u4e2d\u7684\u6f5c\u5728\u4ef7\u503c\uff08\u56fe2A\uff09\u3002\u4f7f\u7528GEPIA\u6570\u636e\u5e93\u4e2d\u7684\u603b\u751f\u5b58\u671f(OS)\u548c\u65e0\u75c5\u751f\u5b58\u671f(DFS)\u8bc4\u4f30CENPO\u5728\u764c\u75c7\u9884\u540e\u4e2d\u7684\u6f5c\u5728\u4ef7\u503c\uff08\u56fe2B, C\uff09\u3002<strong>\uff08ps\uff1aROC\u66f2\u7ebf\u7ed8\u5236\u548c\u5206\u6790\u4e5f\u53ef\u4ee5\u7528\u5c0f\u4e91\u65b0\u5f00\u53d1\u7684\u96f6\u4ee3\u7801\u751f\u4fe1\u5206\u6790\u5c0f\u5de5\u5177\u5b9e\u73b0\uff0c\u4e91\u751f\u4fe1\u5206\u6790\u5de5\u5177\u5e73\u53f0\u5305\u542b\u8d85\u591a\u96f6\u4ee3\u7801\u5c0f\u5de5\u5177\uff0c\u4e0a\u4f20\u6570\u636e\u4e00\u952e\u51fa\u56fe\uff0c\u611f\u5174\u8da3\u7684\u5c0f\u4f19\u4f34\u6b22\u8fce\u6765\u53c2\u89c2\u54df\uff0c\u7f51\u5740\uff1ahttp:\/\/www.biocloudservice.com\/home.html\uff09<\/strong>\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"793\" class=\"wp-image-37987\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-9.png?resize=640%2C793\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-9.png?w=784 784w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-9.png?resize=242%2C300 242w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-9.png?resize=768%2C952 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-9.png?resize=600%2C744 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u56fe2 \u8bca\u65ad\u548c\u9884\u540e\u4ef7\u503c\u5206\u6790<\/p>\n<p><strong>3. CENPO\u8868\u8fbe\u4e0e\u514d\u75ab\u6d78\u6da6\u7684\u76f8\u5173\u6027\u5206\u6790<\/strong><\/p>\n<p>\u4f7f\u7528Sangerbox\u7f51\u7ad9\u5206\u6790\u4e86\u5404\u79cd\u80bf\u7624\u4e2d\u4f30\u8ba1\u8bc4\u5206(\u4f30\u8ba1\u8bc4\u5206\u3001\u514d\u75ab\u8bc4\u5206\u548c\u57fa\u8d28\u8bc4\u5206)\u548cCENPO\u8868\u8fbe\u4e4b\u95f4\u7684\u76f8\u5173\u6027\uff08\u56fe3A\uff09\u3002\u7136\u540e\u4f5c\u8005\u5229\u7528Sangerbox\u6570\u636e\u5e93\u7814\u7a76\u4e86\u5404\u79cd\u80bf\u7624\u4e2dCENPO\u8868\u8fbe\u548cTIIC\u6c34\u5e73\u4e4b\u95f4\u7684\u5173\u7cfb\uff08\u56fe3 B\uff09\uff0c\u4ee5\u53caCENPO\u8868\u8fbe\u4e0e\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027(MSI)\u3001\u80bf\u7624\u7a81\u53d8\u8d1f\u8377(TMB)\u548c\u7a81\u53d8\u7b49\u4f4d\u57fa\u56e0\u80bf\u7624\u5f02\u8d28\u6027(MATH)\u4e4b\u95f4\u7684\u5173\u7cfb\uff08\u56fe3C-E\uff09\u3002\u4f7f\u7528TIMER 2.0\u6570\u636e\u5e93\u7684\u201c\u57fa\u56e0\u201d\u6a21\u5757\u8bc4\u4f3032\u79cd\u80bf\u7624\u7c7b\u578b\u4e2d\u514d\u75ab\u7ec6\u80de\u6d78\u6da6\u7684\u7a0b\u5ea6\uff08\u56fe4\uff09\u3002\u901a\u8fc7TISIDB\u5de5\u5177\u5206\u6790CENPO\u4e0e\u8d8b\u5316\u56e0\u5b50\u7684\u76f8\u5173\u6027\uff08\u56fe5\uff09\u3002<strong>\uff08ps\uff1a\u5404\u79cd\u514d\u75ab\u6d78\u6da6\u4e5f\u53ef\u4ee5\u7528\u4e91\u751f\u4fe1\u5e73\u53f0\u5206\u6790\u5de5\u5177\u5b9e\u73b0\u54e6\uff0c\u7f51\u5740\uff1a<a href=\"http:\/\/www.biocloudservice.com\/home.html\">http:\/\/www.biocloudservice.com\/home.html<\/a>\uff0c\u6b22\u8fce\u670b\u53cb\u4eec\u6765\u63a2\u7d22~ ~\uff09<\/strong><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"585\" height=\"540\" class=\"wp-image-37988\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-10.png?resize=585%2C540\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-10.png?w=585 585w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-10.png?resize=300%2C277 300w\" sizes=\"(max-width: 585px) 100vw, 585px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"448\" class=\"wp-image-37989\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-11.png?resize=640%2C448\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-11.png?w=832 832w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-11.png?resize=300%2C210 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-11.png?resize=768%2C537 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-11.png?resize=600%2C420 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"440\" height=\"382\" class=\"wp-image-37990\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-12.png?resize=440%2C382\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-12.png?w=440 440w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-12.png?resize=300%2C260 300w\" sizes=\"(max-width: 440px) 100vw, 440px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"447\" height=\"372\" class=\"wp-image-37991\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-13.png?resize=447%2C372\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-13.png?w=447 447w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-13.png?resize=300%2C250 300w\" sizes=\"(max-width: 447px) 100vw, 447px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"479\" height=\"404\" class=\"wp-image-37992\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-14.png?resize=479%2C404\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-14.png?w=479 479w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-14.png?resize=300%2C253 300w\" sizes=\"(max-width: 479px) 100vw, 479px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u56fe3 CENPO\u8868\u8fbe\u4e0e\u514d\u75ab\u6d78\u6da6\u7ec6\u80de\u3001MSI\u3001TMB\u3001MATH\u7684\u76f8\u5173\u6027\u5206\u6790<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"307\" class=\"wp-image-37993\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-15.png?resize=640%2C307\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-15.png?w=1060 1060w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-15.png?resize=300%2C144 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-15.png?resize=1024%2C491 1024w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-15.png?resize=768%2C368 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-15.png?resize=600%2C288 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u56fe4 CENPO\u8868\u8fbe\u4e0e\u514d\u75ab\u7ec6\u80de\u6d78\u6da6\u7684\u76f8\u5173\u6027\u5206\u6790<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"537\" height=\"514\" class=\"wp-image-37994\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-16.png?resize=537%2C514\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-16.png?w=537 537w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-16.png?resize=300%2C287 300w\" sizes=\"(max-width: 537px) 100vw, 537px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u56fe5 CENPO\u8868\u8fbe\u4e0e\u8d8b\u5316\u56e0\u5b50\u7684\u76f8\u5173\u6027\u5206\u6790<\/p>\n<p><strong>4.<\/strong> <strong>CENPO\u7a81\u53d8\u7279\u5f81\u53ca\u529f\u80fd\u5206\u6790<\/strong><\/p>\n<p>\u4f7f\u7528cBioPortal\u5de5\u5177\u5206\u6790\u4e0d\u540c\u80bf\u7624\u4e2dCENPO\u7684\u7a81\u53d8\u7279\u5f81\uff0c\u7814\u7a76\u6cdb\u764c\u7ec4\u7ec7\u4e2dCENPO\u7684\u6539\u53d8\u9891\u7387\uff08\u56fe6A\uff09\u548c\u4f53\u7ec6\u80de\u7a81\u53d8\u7684\u4e9a\u578b\u53ca\u5206\u5e03\uff08\u56fe6B\uff09\u3002\u63a5\u4e0b\u6765\u4f5c\u8005\u5229\u7528LinkedOmics \u6570\u636e\u5e93\u7b5b\u9009CENPO\u57fa\u56e0\u5728LUAD\u4e2d\u7684\u5171\u8868\u8fbe\u57fa\u56e0\uff08\u56fe6D\uff09\uff0c\u5e76\u9488\u5bf9LUAD\u961f\u5217\u4e2dCENPO\u5171\u8868\u8fbe\u57fa\u56e0\u8fdb\u884cGO\u548cKEGG\u5206\u6790\uff08\u56fe6E\uff09\u3002\u7ed3\u679c\u8868\u660e\uff0cCENPO\u53ef\u80fd\u5728LUAD\u7684\u7ec6\u80de\u5468\u671f\u8c03\u63a7\u4e2d\u53d1\u6325\u5173\u952e\u4f5c\u7528\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"448\" class=\"wp-image-37995\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-17.png?resize=640%2C448\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-17.png?w=702 702w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-17.png?resize=300%2C210 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-17.png?resize=600%2C420 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"318\" height=\"292\" class=\"wp-image-37996\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-18.png?resize=318%2C292\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-18.png?w=318 318w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-18.png?resize=300%2C275 300w\" sizes=\"(max-width: 318px) 100vw, 318px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"538\" height=\"590\" class=\"wp-image-37997\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-19.png?resize=538%2C590\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-19.png?w=538 538w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-19.png?resize=274%2C300 274w\" sizes=\"(max-width: 538px) 100vw, 538px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u56fe6 CENPO\u7a81\u53d8\u7279\u5f81\u53ca\u529f\u80fd\u5206\u6790<\/p>\n<p><strong>5.<\/strong> <strong>\u8c03\u63a7CENPO\u8868\u8fbe\u7684ceRNA\u7f51\u7edc\u7684\u6784\u5efa\u548c\u5355\u7ec6\u80de\u5206\u6790<\/strong><\/p>\n<p>\u901a\u8fc7miRDB\u3001miRWalk\u3001Targetscan\u548cmiRabel\u6570\u636e\u5e93\u9884\u6d4b\u4e86CENPO\u7684\u4e0a\u6e38miRNAs\uff0c\u5e76\u83b7\u53d6\u4e8682\u4e2a\u4ea4\u96c6miRNAs\uff08\u56fe7A\uff09\uff0c\u5c06\u5176\u4e0e43\u4e2aLUAD\u9884\u540e\u76f8\u5173\u5dee\u5f02miRNAs\u53d6\u4ea4\u96c6\uff0c\u83b7\u5f97miR-370\uff08\u56fe7B\uff09\u3002\u63a5\u4e0b\u6765\u4f5c\u8005\u4f7f\u7528LncBase\u6570\u636e\u5e93\u786e\u5b9a\u4e8661\u4e2a\u4ee5\u9776\u5411hsa-miR-370\u7684lncRNA\uff0c\u5176\u4e2d\u53ea\u670910\u4e2alncRNA\u4e0eLUAD\u60a3\u8005\u7684\u9884\u540e\u663e\u8457\u76f8\u5173\uff08\u56fe7D\uff09\uff0c\u5229\u752883\u4e2amiRNA\u548c10\u4e2a\u9a8c\u8bc1\u7684lncRNA\u6784\u5efalncRNA-miRNA-CENPO\u8c03\u63a7\u7f51\u7edc\uff08\u56fe7C\uff09\u3002\u4f7f\u7528CancerSEA\u4e2d\u7684\u5355\u7ec6\u80de\u6570\u636e\u5206\u6790\u4e86CENPO\u548c18\u79cd\u764c\u75c7\u7684\u529f\u80fd\u72b6\u6001\u4e4b\u95f4\u7684\u5173\u8054\uff08\u56fe7E\uff09\uff0c\u7ed3\u679c\u663e\u793aCENPO\u4e0e\u5927\u591a\u6570\u764c\u75c7\u7684\u7ec6\u80de\u5468\u671f\u3001DNA\u635f\u4f24\u548cDNA\u4fee\u590d\u6b63\u76f8\u5173\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"626\" height=\"475\" class=\"wp-image-37998\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-20.png?resize=626%2C475\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-20.png?w=626 626w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-20.png?resize=300%2C228 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-20.png?resize=600%2C455 600w\" sizes=\"(max-width: 626px) 100vw, 626px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"408\" height=\"478\" class=\"wp-image-37999\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-21.png?resize=408%2C478\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-21.png?w=408 408w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-21.png?resize=256%2C300 256w\" sizes=\"(max-width: 408px) 100vw, 408px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"401\" height=\"268\" class=\"wp-image-38000\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-22.png?resize=401%2C268\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-22.png?w=401 401w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-22.png?resize=300%2C200 300w\" sizes=\"(max-width: 401px) 100vw, 401px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"631\" height=\"577\" class=\"wp-image-38001\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-23.png?resize=631%2C577\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-23.png?w=631 631w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-23.png?resize=300%2C274 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-23.png?resize=600%2C549 600w\" sizes=\"(max-width: 631px) 100vw, 631px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u56fe7 ceRNA\u7f51\u7edc\u7684\u6784\u5efa\u548c\u5355\u7ec6\u80de\u5206\u6790<\/p>\n<p><strong>6.<\/strong> <strong>CENPO\u7684\u8868\u8fbe\u548c\u529f\u80fd\u9a8c\u8bc1<\/strong><\/p>\n<p>\u901a\u8fc7\u4e34\u5e8a\u7ec4\u7ec7\u6837\u672cIHC\u67d3\u8272\u5206\u6790CENPO\u5728LUAD\u7ec4\u7ec7\u548c\u76f8\u5e94\u6b63\u5e38\u7ec4\u7ec7\u4e2d\u7684\u8868\u8fbe\u5dee\u5f02\uff08\u56fe8A\uff09\u3002\u5728A549\u548cHCI-H1299\u7ec6\u80de\u4e2d\u7684\u6c89\u9ed8CENPO\uff0c\u901a\u8fc7\u6d41\u5f0f\u5b9e\u9a8c\u68c0\u6d4b\u7ec6\u80de\u51cb\u4ea1\u548c\u5468\u671f\uff0c\u7ed3\u679c\u53d1\u73b0CENPO\u7684\u6c89\u9ed8\u663e\u8457\u8bf1\u5bfc\u4e86\u7ec6\u80de\u51cb\u4ea1(\u56fe8B)\u548cG2\/M\u671f\u7684\u505c\u6ede\uff08\u56fe8C\uff09\u3002\u63a5\u4e0b\u6765\u4f5c\u8005\u53c8\u7528Celigo\u67d3\u8272\u6cd5\u68c0\u6d4b\u4e86\u7ec6\u80de\u589e\u6b96\uff0c\u901a\u8fc7\u4f24\u53e3\u6108\u5408\u548ctranswell\u5b9e\u9a8c\u68c0\u6d4b\u7ec6\u80de\u8fc1\u79fb\u548c\u4fb5\u88ad\uff0c\u53d1\u73b0CENPO\u6c89\u9ed8\u6291\u5236\u4e86\u7ec6\u80de\u589e\u6b96\uff08\u56fe9A\uff09\uff0c\u8fc1\u79fb\u548c\u4fb5\u88ad\uff08\u56fe9B, C\uff09\u3002\u968f\u540e\u53c8\u901a\u8fc7\u5c0f\u9f20\u5f02\u79cd\u79fb\u690d\u6a21\u578b\u518d\u6b21\u9a8c\u8bc1CENPO\u7684\u529f\u80fd\uff08\u56fe10A-E\uff09\uff0c\u5e76\u901a\u8fc7WB\u7b80\u5355\u63a2\u7d22\u4e86\u4e0b\u6e38\u901a\u8def\u86cb\u767d\u8868\u8fbe\uff08\u56fe10F\uff09\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"308\" class=\"wp-image-38002\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-24.png?resize=640%2C308\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-24.png?w=911 911w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-24.png?resize=300%2C144 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-24.png?resize=768%2C369 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-24.png?resize=600%2C288 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"162\" class=\"wp-image-38003\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-25.png?resize=640%2C162\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-25.png?w=745 745w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-25.png?resize=300%2C76 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-25.png?resize=600%2C151 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"170\" class=\"wp-image-38004\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-26.png?resize=640%2C170\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-26.png?w=779 779w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-26.png?resize=300%2C80 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-26.png?resize=768%2C204 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-26.png?resize=600%2C159 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u56fe8 CENPO\u8868\u8fbe\u9a8c\u8bc1\u548c\u7ec6\u80de\u51cb\u4ea1\u3001\u5468\u671f\u5b9e\u9a8c<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"391\" height=\"367\" class=\"wp-image-38005\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-27.png?resize=391%2C367\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-27.png?w=391 391w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-27.png?resize=300%2C282 300w\" sizes=\"(max-width: 391px) 100vw, 391px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"415\" height=\"435\" class=\"wp-image-38006\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-28.png?resize=415%2C435\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-28.png?w=415 415w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-28.png?resize=286%2C300 286w\" sizes=\"(max-width: 415px) 100vw, 415px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"417\" height=\"330\" class=\"wp-image-38007\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-29.png?resize=417%2C330\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-29.png?w=417 417w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-29.png?resize=300%2C237 300w\" sizes=\"(max-width: 417px) 100vw, 417px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u56fe9 \u7ec6\u80de\u589e\u6b96\u3001\u8fc1\u79fb\u548c\u4fb5\u88ad\u5b9e\u9a8c<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"186\" class=\"wp-image-38008\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-30.png?resize=640%2C186\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-30.png?w=907 907w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-30.png?resize=300%2C87 300w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-30.png?resize=768%2C223 768w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-30.png?resize=600%2C174 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"474\" height=\"328\" class=\"wp-image-38009\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-31.png?resize=474%2C328\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-31.png?w=474 474w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-31.png?resize=300%2C208 300w\" sizes=\"(max-width: 474px) 100vw, 474px\" data-recalc-dims=\"1\" \/> <img decoding=\"async\" loading=\"lazy\" width=\"367\" height=\"415\" class=\"wp-image-38010\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-32.png?resize=367%2C415\" srcset=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-32.png?w=367 367w, https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/04\/word-image-37978-32.png?resize=265%2C300 265w\" sizes=\"(max-width: 367px) 100vw, 367px\" data-recalc-dims=\"1\" \/><\/p>\n<p>\u56fe10 \u5c0f\u9f20\u5f02\u79cd\u79fb\u690d\u5b9e\u9a8c<\/p>\n<p><strong>\u6587\u7ae0\u5c0f\u7ed3<\/strong><\/p>\n<p>\u8fd9\u4e2a\u6587\u7ae0\u9488\u5bf9\u5355\u4e2a\u57fa\u56e0\u8fdb\u884c\u6cdb\u764c\u5206\u6790\uff0c\u5e94\u7528\u8d85\u591a\u5728\u7ebf\u6570\u636e\u5e93\u548c\u7f51\u7ad9\u8fdb\u884c\u5206\u6790\u662f\u6587\u7ae0\u7684\u5927\u4eae\u70b9\uff0c\u6574\u4e2a\u5206\u6790\u601d\u8def\u5f88\u6e05\u6670\uff0c\u65b9\u6cd5\u4e5f\u6bd4\u8f83\u7b80\u5355\uff0c\u975e\u5e38\u9002\u5408\u65b0\u624b\u5c0f\u767d\uff01\u6587\u7ae0\u8fd8\u5305\u542b\u5355\u7ec6\u80de\u6570\u636e\u5206\u6790\u548c\u6e7f\u5b9e\u9a8c\u9a8c\u8bc1\uff0c\u53c8\u8fdb\u4e00\u6b65\u63d0\u5347\u4e86\u6587\u7ae0\u8d28\u91cf\uff0c\u62ff\u4e0b\u4e867\u5206+\u7684\u6210\u7ee9\uff0c\u6570\u636e\u91cf\u548c\u521b\u65b0\u70b9\u6ee1\u6ee1\uff0c\u624b\u63e1\u76ee\u6807\u57fa\u56e0\u60f3\u505a\u521b\u65b0\u6027\u5206\u6790\u7684\u5c0f\u4f19\u4f34\uff0c\u4e0d\u8981\u72b9\u8c6b\u5566\uff0c\u7528\u4e0a\u8fd9\u4e2a\u601d\u8def\u6362\u4e2a\u57fa\u56e0\u53bb\u590d\u73b0\u5427\uff01<\/p>\n<p><strong>\u5c0f\u4e91\u6709\u8bdd\u8bf4<\/strong><\/p>\n<p><strong>\u5c0f\u4e91\u516c\u4f17\u53f7\u6301\u7eed\u4e3a\u5927\u5bb6\u5e26\u6765\u6700\u65b0\u751f\u4fe1\u601d\u8def\uff0c\u66f4\u591a\u521b\u65b0\u6027\u5206\u6790\u601d\u8def\u8bf7\u70b9\u51fb\u94fe\u63a5\uff08https:\/\/mp.weixin.qq.com\/s\/ItrY4vidvuV4NwywnSI_TA\uff09\u3002\u60f3\u590d\u73b0\u8fd9\u79cd\u601d\u8def\u6216\u8005\u5b9a\u5236\u66f4\u591a\u521b\u65b0\u6027\u601d\u8def\u6b22\u8fce\u76f4\u63a5call\u5c0f\u4e91\uff0c\u4e91\u751f\u4fe1\u56e2\u961f\u7aed\u8bda\u4e3a\u60a8\u7684\u79d1\u7814\u52a9\u529b\uff01 <\/strong><\/p>\n<p>1. \u5355\u57fa\u56e0\u5206\u6790\u65b0\u601d\u8def\u6765\u88ad\u2014\u2014\u591a\u7ec4\u5b66\u5206\u6790+\u6570\u5b57\u56fe\u50cf\u5206\u6790=8\u5206+\u7eaf\u751f\u4fe1\uff0c\u8fd0\u7528\u591a\u79cd\u6570\u636e\u5e93\uff0c\u521b\u65b0\u6027\u8d85\u8d5e!\uff01<\/p>\n<p>2. \u75c5\u7406\u5206\u6790\u4e0e\u751f\u4fe1\u5f3a\u5f3a\u8054\u624b\uff0c\u5355\u57fa\u56e0\u5206\u6790+\u514d\u75ab\u5206\u6790\u76f4\u8fbe5.7\u5206+\uff0c\u521b\u65b0\u6027\u7edd\u7edd\u5b50\uff0c\u4e0d\u6015\u601d\u8def\u649e\u8f66!\uff01<\/p>\n<p>3. \u4ec0\u4e48\uff1f\u53ea\u505a\u516c\u5171\u6570\u636e\u5e93\u5206\u6790\u5c31\u80fd\u53d1\u523010\u5206+ 1\u533aTop\u6587\u7ae0\uff1fSEER\u6570\u636e\u5e93\u5c31\u80fd\u505a\u5230\uff01\u53d1\u6587\u5468\u671f\u76f8\u5f53\u5feb\uff0c\u6293\u7d27\u4e0a\u8f66\uff01<\/p>\n<p>4. \u4e34\u5e8a\u516c\u5171\u6570\u636e\u6316\u6398\u70ed\u6f6e\u53c8\u8d77\uff01\u201cNHANES\u201d\u6570\u636e\u5e93\u6311\u8d77\u5927\u6881\uff0c\u53d1\u9ad8\u5206SCI 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