{"id":43165,"date":"2024-06-01T16:00:17","date_gmt":"2024-06-01T08:00:17","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=43165"},"modified":"2024-06-02T00:00:33","modified_gmt":"2024-06-01T16:00:33","slug":"923bf26130","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=43165","title":{"rendered":"\u4e00\u4e2aR\u5305\u641e\u5b9a\u591a\u7ec4\u5b66\u5206\u6790\uff1fmixOmics-\u591a\u7ec4\u5b66\u6570\u636e\u8054\u5408\u5206\u6790\u4ee5\u53ca\u53ef\u89c6\u5316\u7684\u9ad8\u903c\u683c\u5de5\u5177\u5305\uff01"},"content":{"rendered":"<section style=\"text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-imgfileid=\"100015224\" data-ratio=\"0.2222222222222222\" data-s=\"300,640\" data-src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/81717257621.png?w=640\" data-type=\"png\" data-w=\"900\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/81717257621.png?w=640\"  data-recalc-dims=\"1\" \/><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u6211\u4eec\u751f\u4fe1\u4eba\u5728\u505a\u5206\u6790\u7684\u65f6\u5019\uff0c\u5982\u679c\u9047\u5230\u7684\u662f\u5355\u4e00\u7c7b\u578b\u7684\u6570\u636e\uff0c\u5982\u7532\u57fa\u5316\u6570\u636e\uff0c\u8f6c\u5f55\u7ec4\u5b66\u6570\u636e\u3001\u4ee3\u8c22\u7ec4\u5b66\u6570\u636e\u7b49\uff0c\u6211\u4eec\u53ef\u80fd\u662f\u624b\u62ff\u628a\u6390\uff0c\u4fe1\u624b\u634f\u6765\u3002\u5982\u679c\u6211\u4eec\u9047\u5230\u7684\u662f\u591a\u79cd\u7ec4\u5b66\u6570\u636e\u5462\uff0c\u6211\u4eec\u53ef\u80fd\u8fd8\u662f\u6bcf\u4e00\u7c7b\u6570\u636e\u90fd\u7ed9\u4ed6\u5355\u4e00\u5206\u6790\u4e00\u904d\uff0c\u54fc\u54e7\u54fc\u54e7\u5206\u6790\u4e00\u987f\uff0c\u6bcf\u4e2a\u7c7b\u578b\u90fd\u6309\u7167\u5e38\u89c4\u6d41\u7a0b\u5206\u6790\u51fa\u6765\uff0c\u5f53\u7136\u53ef\u4ee5\uff0c\u628a\u7ed3\u679c\u4e00\u7f57\u5217\uff0c\u6211\u4eec\u7684\u5206\u6790\u5185\u5bb9\u4e5f\u4f1a\u663e\u5f97\u5f88\u4e30\u5bcc\u3002\u4f46\u662f\uff0c\u5927\u5bb6\u6709\u6ca1\u6709\u60f3\u8fc7\uff0c\u8fd9\u6837\u5355\u4e00\u7684\u5206\u6790\u4f1a\u5ffd\u7565\u4e0d\u540c\u7279\u5f81\u4e4b\u95f4\u7684\u5173\u7cfb\uff0c\u5f88\u6709\u53ef\u80fd\u56e0\u6b64\u5ffd\u7565\u5173\u952e\u7684\u4fe1\u606f\uff01\u96be\u9053\u6211\u4eec\u5c31\u4e0d\u80fd\u591a\u7ec4\u5b66\u6570\u636e\u5171\u540c\u5206\u6790\u5417\uff1f<\/span><span style=\"line-height: 150%;font-family: Calibri;font-variant: normal;text-transform: none;\">mixOmics\u5e2e\u6211\u4eec\u89e3\u51b3\u4e86\u8fd9\u4e48\u4e00\u5927\u95ee\u9898<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\uff01\u5b83\u53ef\u4ee5\u8ba9\u6211\u4eec\u5c06\u4e0d\u540c\u7684\u7ec4\u5b66\u6570\u636e\u8fdb\u884c\u9884\u5904\u7406\u540e\u5171\u540c\u5206\u6790\uff0c\u5e76\u5c06\u95ee\u9898\u4e3b\u8981\u653e\u5728\u7279\u5f81\u9009\u62e9\u4e0a\uff0c\u5176\u5728\u591a\u7ec4\u5b66\u9886\u57df\u77e5\u540d\u5ea6\u4e5f\u662f\u5f88\u9ad8\uff0c\u6587\u7ae0\u5f15\u7528\u91cf\u4e5f\u5f88\u9ad8\uff0c\u4e0b\u56fe\u662f\u8be5R\u5305\u7684\u6587\u7ae0\uff1a<\/span><\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: Calibri;font-variant: normal;text-transform: none;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100015166\" data-ratio=\"0.25277777777777777\" data-src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/61717257623.png?resize=535%2C135\" data-type=\"png\" data-w=\"1080\" height=\"135 .39996337890625\" width=\"535 .6699829101562\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/61717257623.png?resize=535%2C135\"  data-recalc-dims=\"1\" \/><span style=\"font-variant: normal;text-transform: none;font-family: \u5b8b\u4f53;text-align: justify;text-indent: 0em;letter-spacing: 0.034em;caret-color: transparent;\">\u6587\u4e2d\u6307\u51fa\uff0c\u7814\u7a76\u56e2\u961f\u63a8\u51fa\u7684mixOmics\uff0c\u662f\u4e00\u4e2a\u4e13\u95e8\u7528\u4e8e\u751f\u7269\u6570\u636e\u96c6\u591a\u53d8\u91cf\u5206\u6790\u7684R\u5305\uff0c\u7279\u522b\u5173\u6ce8\u6570\u636e\u63a2\u7d22\u3001\u964d\u7ef4\u548c\u53ef\u89c6\u5316\u3002\u901a\u8fc7\u91c7\u7528\u7cfb\u7edf\u751f\u7269\u5b66\u65b9\u6cd5\uff0c\u8be5\u5de5\u5177\u5305\u63d0\u4f9b\u4e86\u591a\u79cd\u65b9\u6cd5\uff0c\u53ef\u4ee5\u540c\u65f6\u7edf\u8ba1\u6574\u5408\u591a\u4e2a\u6570\u636e\u96c6\uff0c\u4ee5\u63a2\u7d22\u5f02\u6784\u201c\u7ec4\u5b66\u201d\u6570\u636e\u96c6\u4e4b\u95f4\u7684\u5173\u7cfb\u3002\u7b80\u800c\u8a00\u4e4b\uff0cmixOmics\u4e3b\u8981\u6709\u4e09\u79cd\u5206\u6790\u6a21\u5f0f\uff1a<\/span><\/span><\/section>\n<section style=\"font-size: 12pt;font-family: Calibri;font-weight: normal;margin: 8px 0pt 0px;text-align: justify;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 16px;\">\uff081\uff09\u5728\u9762\u5bf9\u5355\u7c7b\u7ec4\u5b66\u6570\u636e\u65f6\uff0c\u53ef\u4ee5\u4f7f\u7528PCA\uff0csPCA\u8fdb\u884c\u964d\u7ef4\u4ee5\u53ca\u7279\u5f81\u7b5b\u9009\uff0c\u800c\u9762\u5bf9\u6709\u76d1\u7763\u7684\u6570\u636e\u7c7b\u578b\u65f6\uff0c\u53ef\u4ee5\u8f6c\u800c\u4f7f\u7528PLS-DA\uff0csPLS-DA\u5728\u8003\u8651\u6837\u672c\u5206\u7c7b\u4fe1\u606f\u7684\u60c5\u51b5\u4e0b\u5c06\u6837\u672c\u6295\u5c04\u5230\u4f4e\u7ef4\u7a7a\u95f4\u4e2d\u5e76\u8fdb\u884c\u5206\u6790\u3002<\/span><\/section>\n<section style=\"font-size: 12pt;font-family: Calibri;font-weight: normal;margin: 8px 0pt 0px;text-align: justify;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\uff082\uff09\u800c\u9762\u5bf9\u591a\u79cd\u4e0d\u540c\u7c7b\u578b\u7ec4\u5b66\u6570\u636e\u65f6\uff0c\u53ef\u4ee5\u4f7f\u7528N-\u96c6\u6210\uff08DIABLO\uff09\u5c06\u4e0d\u540c\u6570\u636e\u8054\u5408\u8d77\u6765\uff0c\u4f8b\u5982\u57fa\u56e0\u7ec4\uff0cmRNA\u6570\u636e\uff0c\u86cb\u767d\u7ec4\u5b66\u4ee5\u53ca\u4ee3\u8c22\u7ec4\u5b66\u7684\u8054\u5408\u5206\u6790\u3002<\/span> &nbsp; &nbsp;<\/span><o:page><\/o:page><\/section>\n<section style=\"font-size: 12pt;font-family: Calibri;font-weight: normal;margin: 8px 0pt 0px;text-align: justify;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 16px;\">\uff083\uff09\u9762\u5bf9\u591a\u7ec4\u76f8\u540c\u7c7b\u578b\u7ec4\u5b66\u6570\u636e\u65f6\uff0c\u53ef\u4ee5\u4f7f\u7528P-\u96c6\u6210\uff08MINT\uff09\u65b9\u6cd5\uff0c\u5982\u5bf9\u4e0d\u540c\u7684\u86cb\u767d\u7ec4\u5b66\u6570\u636e\u8fdb\u884c\u8054\u5408\u5206\u6790\u3002<\/span><\/section>\n<section style=\"font-size: 12pt;font-family: Calibri;font-weight: normal;margin: 8px 0pt 0px;text-align: justify;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u4eca\u5929\u5c0f\u679c\u4f1a\u7ed9\u5927\u5bb6\u5c55\u793a\u8be5\u9879\u76ee\u7b2c\u4e00\u79cd\u5206\u6790\u6a21\u5f0f\u7684\u793a\u4f8b\u6570\u636e\u53ca\u4ee3\u7801\uff0c\u4e5f\u662f\u6211\u4eec\u6700\u5e38\u7528\u7684\u4e00\u79cd\u60c5\u51b5\u3002<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 176, 80);\">\u7279\u522b\u63d0\u793a\uff0c\u672c\u6b21\u64cd\u4f5c\u5bf9\u7535\u8111\u914d\u7f6e\u6709\u4e00\u5b9a\u9700\u6c42\uff0c\u5efa\u8bae\u5927\u5bb6\u4f7f\u7528\u670d\u52a1\u5668\u8fd0\u884c\uff0c\u5982\u679c\u6ca1\u6709\u81ea\u5df1\u7684\u670d\u52a1\u5668\u6b22\u8fce\u8054\u7cfb\u6211\u4eec\u6765\u79df\u8d41\u670d\u52a1\u5668\u54e6\uff5e<\/span><\/span><\/section>\n<section style=\"font-size: 15px;padding-right: 2px;padding-left: 2px;margin-bottom: 0px;\">\n<section style=\"text-wrap: wrap;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"color: rgb(171, 25, 66);font-size: 16px;\"><strong>\u9700\u8981\u79df\u8d41\u670d\u52a1\u5668\u7684\u5c0f\u4f19\u4f34\u53ef\u4ee5\u626b\u7801\u6dfb\u52a0\u5c0f\u679c\uff0c\u6b64\u5916\u5c0f\u679c\u8fd8\u63d0\u4f9b\u751f\u4fe1\u5206\u6790\uff0c\u601d\u8def\u8bbe\u8ba1\uff0c\u6587\u732e\u590d\u73b0\u7b49\uff0c\u6709\u9700\u8981\u7684\u5c0f\u4f19\u4f34\u6b22\u8fce\u6765\u64a9~<\/strong><\/span><\/section>\n<section style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-imgfileid=\"100018585\" data-ratio=\"1\" data-s=\"300,640\" data-src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/21717257624.jpg?w=640\" data-type=\"jpeg\" data-w=\"430\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/21717257624.jpg?w=640\"  data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"font-size: 12pt;font-family: Calibri;font-weight: normal;margin: 8px 0pt 0px;text-align: justify;break-before: auto;break-after: auto;word-break: normal;direction: ltr;text-indent: 0em;line-height: 1.6em;\"><br  \/><\/section>\n<section style=\"text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;color: windowtext;font-family: \u5b8b\u4f53;text-indent: 0em;letter-spacing: 0.034em;\">\u6b63\u5f0f\u8bb2\u89e3\u6d41\u7a0b\u4e4b\u524d\uff0c\u5927\u5bb6\u5148\u770b\u4e00\u4e0b\u4e09\u79cd\u5206\u6790\u7684\u793a\u610f\u56fe\uff0c\u8be5\u793a\u610f\u56fe\u5f88\u76f4\u89c2\u5730\u5c55\u793a\u4e86\u4e09\u79cd\u6570\u636e\u7c7b\u578b\uff0c\u65b9\u4fbf\u5927\u5bb6\u8fdb\u884c\u7406\u89e3\uff0c\u5982\u4e0b\u56fe\uff1a<br  \/><\/span><\/section>\n<section style=\"font-size: 12pt;font-family: Calibri;font-weight: normal;margin: 8px 0pt 0px;text-align: center;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: Calibri;font-variant: normal;text-transform: none;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100015167\" data-ratio=\"0.6324074074074074\" data-src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/21717257625.png?resize=523%2C330\" data-type=\"png\" data-w=\"1080\" height=\"330 .94000244140625\" width=\"523 .4099731445312\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/21717257625.png?resize=523%2C330\"  data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"font-size: 12pt;font-family: Calibri;font-weight: normal;margin: 8px 0pt 0px;text-align: justify;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: windowtext;\">\u53ef\u4ee5\u770b\u5230\uff0c\u5de6\u8fb9\u662f\u5355\u4e00\u7ec4\u5b66\u6570\u636e\uff0c\u6839\u636e\u662f\u5426\u6709\u5206\u7c7b\u6807\u7b7e\u5bf9\u5e94\u7740\u4e0d\u540c\u7684\u5206\u6790\u7b56\u7565\uff0c\u4e2d\u95f4\u662f\u4e0d\u540c\u7ec4\u5b66\u6570\u636e\u8054\u5408\uff0c\u8fdb\u884c\u9884\u5904\u7406\u540e\u540c\u6837\u6839\u636e\u6807\u7b7e\u6709\u65e0\u6765\u8fdb\u884c\u5bf9\u5e94\u7684\u5206\u6790\uff0c\u53f3\u8fb9\u662f\u76f8\u540c\u7ec4\u5b66\u6570\u636e\u7684\u8054\u5408\u5206\u6790\u3002\u6211\u4eec\u53ef\u4ee5\u53d1\u73b0\uff0c\u8be5\u5de5\u5177\u5305\u57fa\u672c\u5305\u542b\u4e86\u6211\u4eec\u5904\u7406\u7ec4\u5b66\u6570\u636e\u7684\u6240\u6709\u60c5\u51b5\uff0c\u90a3\u4e48\u63a5\u4e0b\u6765\uff0c\u6211\u5c06\u7ed9\u5927\u5bb6\u5c55\u793a\u4e00\u4e0b\u8be5\u5de5\u5177\u5305\u7684\u7b80\u5355\u64cd\u4f5c\uff0c\u4ee5\u53ca\u5355\u4e00\u7ec4\u5b66\u6570\u636e\u7684\u793a\u4f8b\u5206\u6790\u3002\u5176\u4ed6\u4e24\u79cd\u6a21\u5f0f\u5927\u5bb6\u53ef\u4ee5\u767b\u9646\u5b98\u65b9\u6587\u6863\u81ea\u884c\u67e5\u770b\u54e6\uff5ehttp:\/\/mixomics.org\/<\/span> &nbsp; &nbsp;<\/span><o:page><\/o:page><\/section>\n<section style=\"font-size: 12pt;font-family: Calibri;font-weight: normal;margin: 8px 0pt 0px;text-align: justify;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: Calibri;font-variant: normal;text-transform: none;font-size: 16px;\"> &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;<o:p>&nbsp;<\/o:p><\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;font-size: 16px;\">1.\u7b80\u4ecb<\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">\u5728\u4f7f\u7528\u8be5R\u5305\u5206\u6790\u6570\u636e\u4e4b\u524d\uff0c\u8bf7\u6ce8\u610f\u6570\u636e\u9884\u5904\u7406\u8981\u6c42\uff1a<\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 21pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: Wingdings;font-variant: normal;text-transform: none;font-weight: normal;\">l<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u6570\u636e\u7c7b\u578b\u3002<\/span><\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 21pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">\u53ef\u4ee5\u63a2\u7d22\u548c\u96c6\u6210\u4e0d\u540c\u7c7b\u578b\u7684\u751f\u7269\u6570\u636e\u3002\u8be5R\u5305\u53ef\u4ee5\u5904\u7406\u8fde\u7eed\u89c4\u6a21\u6d4b\u91cf\u7684\u5206\u5b50\u7279\u5f81\uff08\u4f8b\u5982\u5fae\u9635\u5217\u3001\u57fa\u4e8e\u8d28\u8c31\u7684\u86cb\u767d\u8d28\u7ec4\u5b66\u548c\u4ee3\u8c22\u7ec4\u5b66\uff09\u6216\u57fa\u4e8e\u6d4b\u5e8f\u7684\u8ba1\u6570\u6570\u636e\uff08RNA-seq\u300116S\u3001\u9e1f\u67aa\u6cd5\u5b8f\u57fa\u56e0\u7ec4\u5b66\uff09\uff0c\u8fd9\u4e9b\u6570\u636e\u5728\u9884\u5904\u7406\u548c\u6807\u51c6\u5316\u5904\u7406\u540e\u6210\u4e3a\u201c\u8fde\u7eed\u201d\u6570\u636e\u3002<\/span><span style=\"font-family: \u5b8b\u4f53;text-indent: 24pt;letter-spacing: 0.034em;\">&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;<\/span><\/span><o:p style=\"font-family: \u5b8b\u4f53;font-size: 12pt;text-indent: 24pt;letter-spacing: 0.034em;\"><span style=\"font-size: 16px;\">&nbsp;<\/span><\/o:p><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 21pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: Wingdings;font-variant: normal;text-transform: none;font-weight: normal;\">l<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u5f52\u4e00\u5316\u3002<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">\u8be5\u5305\u4e0d\u8fdb\u884c\u5f52\u4e00\u5316\u5904\u7406\uff0c\u56e0\u4e3a\u5b83\u662f\u7279\u5b9a\u4e8e\u5e73\u53f0\u7684\uff0c\u5e76\u4e14\u6db5\u76d6\u7684\u6570\u636e\u79cd\u7c7b\u592a\u591a\u3002\u5728\u5206\u6790\u4e4b\u524d\uff0c\u8be5\u5305\u5047\u8bbe\u6570\u636e\u96c6\u5df2\u4f7f\u7528\u9002\u5f53\u7684\u6807\u51c6\u5316\u65b9\u6cd5\u8fdb\u884c\u6807\u51c6\u5316\uff0c\u5e76\u5728\u9002\u7528\u65f6\u8fdb\u884c\u4e86\u9884\u5904\u7406\u3002<\/span><\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 21pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: Wingdings;font-variant: normal;text-transform: none;font-weight: normal;\">l<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u9884\u8fc7\u6ee4\u3002<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">\u867d\u7136\u8be5R\u5305\u53ef\u4ee5\u5904\u7406\u5927\u578b\u6570\u636e\u96c6\uff08\u6570\u4e07\u4e2a\u9884\u6d4b\u53d8\u91cf\uff09\uff0c\u4f46\u6211\u4eec\u5efa\u8bae\u5c06\u6570\u636e\u9884\u8fc7\u6ee4\u5230\u6bcf\u4e2a\u6570\u636e\u96c6\u5c11\u4e8e 10K \u9884\u6d4b\u53d8\u91cf\uff0c\u4f8b\u5982\u4f7f\u7528\u4e2d\u503c\u7edd\u5bf9\u504f\u5dee\u8fdb\u884cRNA-seq\u6570\u636e\uff0c\u901a\u8fc7\u5220\u9664\u5fae\u751f\u7269\u7ec4\u6570\u636e\u96c6\u4e2d\u4e00\u8d2f\u7684\u4f4e\u8ba1\u6570\u6216\u5220\u9664\u63a5\u8fd1\u96f6\u7684\u65b9\u5dee\u9884\u6d4b\u53d8\u91cf\u3002\u8be5\u6b65\u9aa4\u65e8\u5728\u51cf\u5c11\u53c2\u6570\u8c03\u6574\u8fc7\u7a0b\u4e2d\u7684\u8ba1\u7b97\u65f6\u95f4\u3002<\/span><\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 21pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: Wingdings;font-variant: normal;text-transform: none;font-weight: normal;\">l<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u6570\u636e\u683c\u5f0f\u3002<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">\u6211\u4eec\u7684\u65b9\u6cd5\u4f7f\u7528\u77e9\u9635\u5206\u89e3\u6280\u672f\u3002\u56e0\u6b64\uff0c\u6570\u5b57\u6570\u636e\u77e9\u9635\u6216\u6570\u636e\u6846\u5728\u884c\u4e2d\u5177\u6709<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-style: italic;\">n<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-style: normal;\">\u4e2a<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">\u89c2\u6d4b\u6216\u6837\u672c\uff0c\u5728\u5217\u4e2d\u5177\u6709<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-style: italic;\">p<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-style: normal;\">\u4e2a<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">\u9884\u6d4b\u53d8\u91cf\uff0c\u4f8b\u5982\uff0c\u57fa\u56e0\u3001\u86cb\u767d\u8d28\u3001\u79cd\u4e0b\u5355\u5143\uff08OTUs\uff09\u3002<\/span><\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 21pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: Wingdings;font-variant: normal;text-transform: none;font-weight: normal;\">l<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u534f\u53d8\u91cf\u3002<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">\u5728\u5f53\u524d\u7248\u672c\u4e2d\uff0c\u53ef\u80fd\u4f1a\u6df7\u6dc6\u5206\u6790\u7684\u534f\u53d8\u91cf\u672a\u5305\u542b\u5728\u65b9\u6cd5\u4e2d\u3002\u8be5R\u5305\u5efa\u8bae\u4e8b\u5148\u4f7f\u7528\u9002\u5f53\u7684\u5355\u53d8\u91cf\u6216\u591a\u53d8\u91cf\u65b9\u6cd5\u6821\u6b63\u8fd9\u4e9b\u534f\u53d8\u91cf\uff0c\u4ee5\u6d88\u9664\u6279\u6b21\u6548\u5e94\u3002&nbsp;&nbsp;<\/span><\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">\u7b80\u800c\u8a00\u4e4b\uff0c\u5c31\u662f\u9700\u8981\u6211\u4eec\u63d0\u524d\u5c06\u6211\u4eec\u7684\u6570\u636e\u8fdb\u884c\u5904\u7406\uff0c\u8fd9\u548c\u6211\u4eec\u7684\u5e38\u89c4\u6d41\u7a0b\u5904\u7406\u6570\u636e\u5176\u5b9e\u662f\u4e00\u6837\u7684\u3002<\/span> &nbsp; &nbsp;<\/span><o:page><\/o:page><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;font-size: 16px;\">2.\u5feb\u901f\u4f7f\u7528<\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">\u9996\u5148\uff0c\u7ed9\u5927\u5bb6\u5c55\u793a\u4e00\u4e0b\u5982\u4f55\u5feb\u901f\u5b89\u88c5\u3001\u4f7f\u7528\u8fd9\u4e2aR\u5305\u3002<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">2.1\u5b89\u88c5<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">\u9996\u5148\uff0c\u4eceBioconductor\u4e0b\u8f7d\u6700\u65b0\u7248\u672c\uff1a<\/span><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"php\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">if<\/span> (!requireNamespace(<span class=\"code-snippet__string\">\"BiocManager\"<\/span>, quietly = <span class=\"code-snippet__keyword\">TRUE<\/span>))    install.packages(<span class=\"code-snippet__string\">\"BiocManager\"<\/span>) BiocManager::install(<span class=\"code-snippet__string\">\"mixOmics\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">\u6216\u8005\u4eceGitHub\u5b89\u88c5\uff1a<\/span><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"php\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">BiocManager::install(\"mixOmicsTeam\/mixOmics\")<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\"># \u8be5mixOmics\u5305\u5e94\u4f1a\u76f4\u63a5\u5bfc\u5165\u4ee5\u4e0b\u5305\uff1aigraph, rgl, ellipse, corpcor, RColorBrewer, plyr, parallel, dplyr, tidyr, reshape2, methods, matrixStats, rARPACK, gridExtra\u3002\u5bf9\u4e8eApple mac\u7528\u6237\uff1a\u5982\u679c\u65e0\u6cd5\u5b89\u88c5\u5bfc\u5165\u7684\u5305rgl\uff0c\u5219\u9700\u8981\u5148\u5b89\u88c5XQuartz\u8f6f\u4ef6\u3002<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;line-height: 150%;break-before: auto;break-after: auto;word-break: normal;direction: ltr;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><br  \/><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: &quot;Times New Roman Regular&quot;;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">2.2\u52a0\u8f7d\u5305<\/span><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"apache\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">library(mixOmics)<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\"># \u68c0\u67e5\u52a0\u8f7d\u5305\u65f6\u662f\u5426\u6709\u9519\u8bef\uff0c\u5c24\u5176\u662frgl\u5e93\uff08\u89c1\u4e0a\u6587\uff09<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;line-height: 150%;break-before: auto;break-after: auto;word-break: normal;direction: ltr;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><br  \/><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: &quot;Times New Roman Regular&quot;;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">2.3\u52a0\u8f7d\u6570\u636e<\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">\u4e0b\u9762\u6b65\u9aa4\u7ed9\u51fa\u7684\u793a\u4f8b\u4f7f\u7528\u7684\u6570\u636e\u5df2\u7ecf\u662f\u5305\u7684\u4e00\u90e8\u5206\u3002\u8981\u4e0a\u4f20\u60a8\u81ea\u5df1\u7684\u6570\u636e\uff0c\u8bf7\u9996\u5148\u68c0\u67e5\u60a8\u7684\u5de5\u4f5c\u76ee\u5f55\u662f\u5426\u5df2\u8bbe\u7f6e\uff0c\u7136\u540e\u901a\u8fc7\u4f7f\u7528RStudio \u4e2d\u7684\u201c\u6587\u4ef6\u201d&gt;\u201c\u5bfc\u5165\u6570\u636e\u96c6\u201d\u6216\u901a\u8fc7\u4ee5\u4e0b\u547d\u4ee4\u884c\u4e4b\u4e00\u4ee5.txt\u6216.csv\u8bfb\u53d6\u6570\u636e\u3002<\/span><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"objectivec\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\"># from csv file<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">data &lt;- read.csv(\"your_data.csv\", row.names = 1, header = TRUE)<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\"># from txt file<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">data &lt;- read.table(\"your_data.txt\", header = TRUE)<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><o:page><\/o:page><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: &quot;Times New Roman Regular&quot;;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">2.4\u5feb\u901f\u542f\u52a8mixOmics<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">\u6bcf\u4e2a\u5206\u6790\u90fd\u5e94\u9075\u5faa\u4ee5\u4e0b\u5de5\u4f5c\u6d41\u7a0b\uff1a<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">\uff081\uff09\u8fd0\u884c\u8be5\u65b9\u6cd5<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">\uff082\uff09\u6837\u54c1\u7684\u56fe\u5f62\u8868\u793a<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">\uff083\uff09\u53d8\u91cf\u7684\u56fe\u5f62\u8868\u793a<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">\u4f8b\u5982\uff0c\u5bf9\u4e8e\u4e3b\u6210\u5206\u5206\u6790\uff0c\u6211\u4eec\u9996\u5148\u52a0\u8f7d\u6570\u636e\uff1a<\/span><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"powershell\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">data(nutrimouse) #R\u5305\u81ea\u5e26\u793a\u4f8b\u6570\u636e<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">X &lt;- nutrimouse$gene<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;line-height: 150%;break-before: auto;break-after: auto;word-break: normal;direction: ltr;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><br  \/><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">\u7136\u540e\u4f7f\u7528\u4ee5\u4e0b\u6b65\u9aa4\uff1a<\/span><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"bash\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">MyResult.pca &lt;- pca(X)  # 1 \u8fd0\u884cPCA\u65b9\u6cd5<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">plotIndiv(MyResult.pca)  # 2 \u7ed8\u5236\u6837\u672c\u56fe<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;line-height: 150%;break-before: auto;break-after: auto;word-break: normal;direction: ltr;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><br  \/><\/section>\n<section style=\"margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;text-align: center;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: Calibri;font-variant: normal;text-transform: none;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100015169\" data-ratio=\"0.9878542510121457\" data-src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/11717257626.png?resize=323%2C319\" data-type=\"png\" data-w=\"741\" height=\"319 .5400390625\" width=\"323 .47003173828125\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/11717257626.png?resize=323%2C319\"  data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;line-height: 150%;break-before: auto;break-after: auto;word-break: normal;direction: ltr;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><br  \/><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"bash\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">plotVar(MyResult.pca)   # 3 \u7ed8\u5236\u53d8\u91cf\u56fe<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><o:page><\/o:page><\/section>\n<section style=\"margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;text-align: center;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: Calibri;font-variant: normal;text-transform: none;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100015168\" data-ratio=\"0.9949874686716792\" data-src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/61717257627.png?resize=348%2C346\" data-type=\"png\" data-w=\"798\" height=\"346 .6099853515625\" width=\"348 .4100341796875\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/61717257627.png?resize=348%2C346\"  data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;text-align: justify;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">\u6309\u7167\u6211\u4eec\u6b64\u5904\u7684\u793a\u4f8b\uff0c\u53ef\u4ee5\u5e94\u7528\u7a00\u758f PCA \u6765\u9009\u62e9\u5bf9 PCA \u4e2d\u7684\u4e24\u4e2a\u5206\u91cf\u505a\u51fa\u8d21\u732e\u7684\u524d 5 \u4e2a\u53d8\u91cf\u3002\u7528\u6237\u6307\u5b9a\u5728\u6bcf\u4e2a\u7ec4\u4ef6\u4e0a\u9009\u62e9\u7684\u53d8\u91cf\u6570\u91cf\uff0c\u4f8b\u5982\uff0c\u8fd9\u91cc\u5728\u524d\u4e24\u4e2a\u7ec4\u4ef6\u4e0a\u5206\u522b\u9009\u62e9 5 \u4e2a\u53d8\u91cf (keepX=c(5,5))\uff1a<\/span><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"bash\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">MyResult.spca &lt;- spca(X, keepX=c(5,5)) # 1 \u8fd0\u884cPCA\u65b9\u6cd5<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">plotIndiv(MyResult.spca)             # 2 \u7ed8\u5236\u6837\u672c\u56fe<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;text-align: justify;line-height: 150%;break-before: auto;break-after: auto;word-break: normal;direction: ltr;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><br  \/><\/section>\n<section style=\"margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;text-align: center;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: Calibri;font-variant: normal;text-transform: none;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100015165\" data-ratio=\"0.9936548223350253\" data-src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/31717257627.png?resize=344%2C341\" data-type=\"png\" data-w=\"788\" height=\"341 .6099853515625\" width=\"344 .0099792480469\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/31717257627.png?resize=344%2C341\"  data-recalc-dims=\"1\" \/><\/span><span style=\"font-size: 16px;\"> &nbsp; &nbsp;<\/span><o:page><\/o:page><\/section>\n<section style=\"margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;text-align: justify;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: Calibri;font-variant: normal;text-transform: none;font-size: 16px;\"> &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;<o:p>&nbsp;<\/o:p><\/span><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"bash\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">plotVar(MyResult.spca)          # 3 \u7ed8\u5236\u53d8\u91cf\u56fe<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;line-height: 150%;break-before: auto;break-after: auto;word-break: normal;direction: ltr;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><br  \/><\/section>\n<section style=\"margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;text-align: center;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: Calibri;font-variant: normal;text-transform: none;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100015171\" data-ratio=\"1.004950495049505\" data-src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/81717257628.png?resize=352%2C354\" data-type=\"png\" data-w=\"808\" height=\"354 .469970703125\" width=\"352 .6100158691406\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/81717257628.png?resize=352%2C354\"  data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">\u53ef\u4ee5\u770b\u5230\u6211\u4eec\u5df2\u7ecf\u5927\u5927\u51cf\u5c11\u4e86\u76f8\u5173\u5706\u56fe\u4e2d\u7684\u57fa\u56e0\u6570\u91cf<\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;font-size: 16px;\">3.PCA\u793a\u4f8b\u5206\u6790<\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">\u4e3a\u4e86\u6f14\u793aPCA\u548c\u5176\u53d8\u4f53\uff0c\u6211\u4eec\u5c06\u5206\u6790multidrug\u5305\u4e2d\u63d0\u4f9b\u7684\u6848\u4f8b\u7814\u7a76\u3002\u8fd9\u9879\u836f\u7269\u57fa\u56e0\u7ec4\u5b66\u7814\u7a76\u8c03\u67e5\u4e86\u764c\u7ec6\u80de\u7cfb\u4e2d\u7684\u836f\u7269\u6d3b\u6027\u6a21\u5f0f\u3002\u8fd9\u4e9b\u7ec6\u80de\u7cfb\u6765\u81ea\u7f8e\u56fd\u56fd\u5bb6\u764c\u75c7\u7814\u7a76\u6240(NCI)\u53d1\u80b2\u6cbb\u7597\u8ba1\u5212\u5efa\u7acb\u7684<\/span><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;text-decoration: none;\">NCI-60\u4eba\u7c7b\u80bf\u7624\u7ec6\u80de\u7cfb\uff0c<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">\u7528\u4e8e\u7b5b\u9009\u4e0d\u540c\u764c\u7ec6\u80de\u7cfb\u4e2d\u5316\u5b66\u5316\u5408\u7269\u5e93\u7684\u6bd2\u6027\u3002NCI-60\u5305\u62ec\u6e90\u81ea\u7ed3\u76f4\u80a0\u764c\uff087\u4e2a\u7ec6\u80de\u7cfb\uff09\u3001\u80be\u764c\uff088\u4e2a\u7ec6\u80de\u7cfb\uff09\u3001\u5375\u5de2\u764c\uff086\u4e2a\u7ec6\u80de\u7cfb\uff09\u3001\u4e73\u817a\u764c\uff088\u4e2a\u7ec6\u80de\u7cfb\uff09\u3001\u524d\u5217\u817a\u764c\uff082\u4e2a\u7ec6\u80de\u7cfb\uff09\u3001\u80ba\u764c\uff089\u4e2a\u7ec6\u80de\u7cfb\uff09\u548c\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u6765\u6e90\u7684\u764c\u75c7\uff086\u4e2a\u7ec6\u80de\u7cfb\uff09\uff0c\u4ee5\u53ca\u767d\u8840\u75c5\uff086\u4e2a\u7ec6\u80de\u7cfb\uff09\u548c\u9ed1\u8272\u7d20\u7624\uff088\u4e2a\u7ec6\u80de\u7cfb\uff09\u3002<\/span><\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">\u6211\u4eec\u6f14\u793a\u4e3b\u8981\u4f7f\u7528multidrug\u4e2d\u7684\u4ee5\u4e0b\u6570\u636e\uff1a<\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">$ABC.trans\uff1a\u5305\u542b\u901a\u8fc7\u5b9a\u91cf\u5b9e\u65f6 PCR (RT-PCR) \u5bf9\u6bcf\u4e2a\u7ec6\u80de\u7cfb\u6d4b\u91cf\u7684 48 \u79cd\u4eba\u7c7b ABC \u8f6c\u8fd0\u86cb\u767d\u7684\u8868\u8fbe\u3002<\/span> &nbsp; &nbsp;<\/span><o:page><\/o:page><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">$compound\uff1a\u5305\u542b 1,429 \u79cd\u836f\u7269\u7684\u6d3b\u6027\uff0c\u4ee5 GI50 \u8868\u793a\uff0c\u5373\u5bf9\u6d4b\u8bd5\u7ec6\u80de\u7cfb\u7684\u7ec6\u80de\u751f\u957f\u4ea7\u751f 50% \u6291\u5236\u7684\u836f\u7269\u6d53\u5ea6\u3002<\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">$comp.name\uff1a1,429 \u79cd\u5316\u5408\u7269\u7684\u540d\u79f0\u3002<\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">$cell.line\uff1a\u6709\u5173\u7ec6\u80de\u7cfb\u540d\u79f0 (&nbsp;$Sample) \u548c\u7ec6\u80de\u7cfb\u7c7b\u578b (&nbsp;$Class) \u7684\u4fe1\u606f\u3002<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">3.1\u52a0\u8f7d\u6570\u636e<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">\u8f93\u5165\u7684\u6570\u636e\u662f\u77e9\u9635\u7c7b\u578b\uff0c\u5176\u4e2d\u884c\u540d\u4e3a\u6bcf\u4e2a\u6837\u672c\u7684\u540d\u79f0\uff0c\u5217\u540d\u662f\u53d8\u91cf\u7684\u540d\u79f0\uff08\u4f8b\u5982\u57fa\u56e0\uff09\uff0c\u6211\u4eec\u4ece\u6570\u636e$ABC.trans\u5f00\u59cb\uff1a<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;line-height: 150%;break-before: auto;break-after: auto;word-break: normal;direction: ltr;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><br  \/><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"powershell\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">library(mixOmics)<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">data(multidrug)<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">X &lt;- multidrug$ABC.trans<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">dim(X) # \u68c0\u67e5\u6570\u636e\u7684\u7ef4\u5ea6<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">\u7ed3\u679c\uff1a<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">## [1] 60 48<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;line-height: 150%;break-before: auto;break-after: auto;word-break: normal;direction: ltr;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><br  \/><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: &quot;Times New Roman Regular&quot;;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">3.2\u4e3b\u6210\u5206\u5206\u6790<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: &quot;Times New Roman Regular&quot;;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">3.2.1\u9009\u62e9\u4e3b\u6210\u5206\u6570\u91cf<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: &quot;Times New Roman Regular&quot;;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">tune.pca()\u8ba1\u7b97\u5927\u91cf\u4e3b\u6210\u5206\u7684\u89e3\u91ca\u65b9\u5dee\u7684\u7d2f\u79ef\u6bd4\u4f8b\uff08\u8fd9\u91cc\u6211\u4eec\u8bbe\u7f6encomp = 10\uff09\u3002\u8f93\u51fa\u89e3\u91ca\u65b9\u5dee\u76f8\u5bf9\u4e8e\u6bcf\u4e2a\u4e3b\u6210\u5206\u6570\u636e\u65b9\u5dee\u603b\u91cf\u7684\u6bd4\u4f8b\u7684\u7ec6\u7ebf\u56fe\uff1a<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;line-height: 150%;break-before: auto;break-after: auto;word-break: normal;direction: ltr;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><br  \/><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"xml\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">tune.pca.multi &lt;- tune.pca(X, ncomp = 10, scale = TRUE)<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">plot(tune.pca.multi)<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><o:page><\/o:page><\/section>\n<section style=\"margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;text-align: center;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: Calibri;font-variant: normal;text-transform: none;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100015172\" data-ratio=\"0.7696850393700787\" data-src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/61717257628.png?resize=410%2C315\" data-type=\"png\" data-w=\"1016\" height=\"315 .6700134277344\" width=\"410 .1400146484375\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/61717257628.png?resize=410%2C315\"  data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">\u56fe\u793a\u4e3aABC \u8f6c\u8fd0\u86cb\u767d\u6570\u636e\u4e0a\u6bcf\u4e2a\u4e3b\u6210\u5206\u7684\u89e3\u91ca\u65b9\u5dee\u91cf<\/span><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"php\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">tune.pca.multidrug$cum.var       # \u8f93\u51fa\u7d2f\u8ba1\u5dee\u5f02\u6bd4\u4f8b<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;text-indent: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><br  \/><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">\u6211\u4eec\u6839\u636e\u4e0a\u56fe\u7684\u4e0b\u964d\u8d8b\u52bf\uff0c\u6216\u8005\u6839\u636e\u4e0a\u4e00\u6761\u7ed9\u51fa\u4ee3\u7801\u8ba1\u7b97\u7684\u5177\u4f53\u6bd4\u4f8b\u6570\u503c\uff0c\u786e\u5b9a\u524d\u4e24\u4e2a\u6216\u8005\u524d\u4e09\u4e2a\u4e3b\u6210\u5206\u53ef\u4ee5\u4fdd\u7559\u4e0b\u6765\u3002<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: &quot;Times New Roman Regular&quot;;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">3.2.2\u8fd0\u884c\u4e09\u4e2a\u4e3b\u6210\u5206\u7684PCA<\/span><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"xml\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">final.pca.multi &lt;- pca(X, ncomp = 3, center = TRUE, scale = TRUE)<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;text-indent: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><br  \/><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 0);font-weight: normal;font-size: 16px;\">\u8fd9\u91cc\u6570\u636e\u7684\u603b\u65b9\u5dee\u662f\uff1a<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;line-height: 150%;break-before: auto;break-after: auto;word-break: normal;direction: ltr;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><br  \/><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"php\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">final.pca.multi$var.tot<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">\u7ed3\u679c\uff1a<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">## [1] 47.98305<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;text-indent: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><br  \/><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 0);font-weight: normal;font-size: 16px;\">\u901a\u8fc7\u5bf9\u6240\u6709\u53ef\u80fd\u5206\u91cf\u89e3\u91ca\u7684\u65b9\u5dee\u6c42\u548c\uff0c\u6211\u4eec\u5c06\u83b7\u5f97\u76f8\u540c\u6570\u91cf\u7684\u89e3\u91ca\u65b9\u5dee\u3002\u6bcf\u4e2a\u5206\u91cf\u7684\u89e3\u91ca\u65b9\u5dee\u6bd4\u4f8b\u4e3a\uff1a<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;line-height: 150%;break-before: auto;break-after: auto;word-break: normal;direction: ltr;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><br  \/><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"php\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">final.pca.multi$prop_expl_var$X<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">##      PC1         PC2        PC3<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">## 0.12677541  0.10194929  0.07011818<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;text-indent: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><br  \/><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 0);font-weight: normal;\">\u8fd8\u53ef\u4ee5\u63d0\u53d6\u89e3\u91ca\u7684\u65b9\u5dee\u7d2f\u79ef\u6bd4\u4f8b\uff1a<\/span> &nbsp; &nbsp;<\/span><o:page><\/o:page><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;line-height: 150%;break-before: auto;break-after: auto;word-break: normal;direction: ltr;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><br  \/><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"php\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">final.pca.multi$cum.var<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">\u7ed3\u679c\uff1a<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">##      PC1       PC2       PC3<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">## 0.1267754  0.2287247  0.2988429<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;text-indent: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><br  \/><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: &quot;Times New Roman Regular&quot;;font-variant: normal;text-transform: none;color: rgb(0, 0, 0);font-weight: normal;font-size: 16px;\">3.2.3\u8bc6\u522b\u6709\u4ef7\u503c\u7684\u53d8\u91cf<\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 0);font-weight: normal;font-size: 16px;\">\u4e3a\u4e86\u8ba1\u7b97\u5206\u91cf\uff0c\u6211\u4eec\u4f7f\u7528\u52a0\u8f7d\u5411\u91cf\u4e2d\u6307\u793a\u7684\u53ef\u53d8\u7cfb\u6570\u6743\u91cd\u3002\u56e0\u6b64\uff0c\u52a0\u8f7d\u5411\u91cf\u4e2d\u7cfb\u6570\u7684\u7edd\u5bf9\u503c\u544a\u8bc9\u6211\u4eec\u6bcf\u4e2a\u53d8\u91cf\u5bf9\u6bcf\u4e2a\u5206\u91cf\u7684\u5b9a\u4e49\u7684\u91cd\u8981\u6027\u3002\u6211\u4eec\u53ef\u4ee5\u901a\u8fc7\u51fd\u6570\u63d0\u53d6\u6b64\u4fe1\u606f\uff0cselectVar()\u8be5\u51fd\u6570\u6839\u636e\u6bcf\u4e2a\u4e3b\u6210\u5206\u7684\u7edd\u5bf9\u8d1f\u8f7d\u6743\u91cd\u503c\u6309\u964d\u5e8f\u6392\u5217\u6700\u91cd\u8981\u7684\u53d8\u91cf\u3002<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;line-height: 150%;break-before: auto;break-after: auto;word-break: normal;direction: ltr;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><br  \/><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"shell\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">#\u53ea\u6839\u636e\u7b2c\u4e00\u4e3b\u6210\u5206\u6392\u5e8f\u53d8\u91cf:<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">head(selectVar(final.pca.multi, comp = 1)$value)<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">\u7ed3\u679c\uff1a<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">##        value.var<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">## ABCE1  0.3242162<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">## ABCD3  0.2647565<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">## ABCF3  0.2613074<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">## ABCA8 -0.2609394<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">## ABCB7  0.2493680<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">## ABCF1  0.2424253<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;text-indent: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><br  \/><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: &quot;Times New Roman Regular&quot;;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">3.2.4\u6837\u672c\u56fe\u7ed8\u5236<\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">\u6211\u4eec\u5c06\u6837\u672c\u6295\u5f71\u5230\u4e3b\u6210\u5206\u6240\u5728\u7684\u7a7a\u95f4\u4e2d\uff0c\u4ee5\u53ef\u89c6\u5316\u6837\u672c\u5982\u4f55\u805a\u7c7b\u5e76\u8bc4\u4f30\u6570\u636e\u4e2d\u7684\u751f\u7269\u6216\u6280\u672f\u53d8\u5316\u3002<\/span><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"php\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">plotIndiv(final.pca.multi,<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">          comp = c(1, 2),   # Specify components to plot<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">          ind.names = TRUE, # Show row names of samples<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">          group = multidrug$cell.line$Class,    <\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">          title = 'ABC transporters, PCA comp 1 - 2',<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">          legend = TRUE, legend.title = 'Cell line')<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;text-indent: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><br  \/><\/section>\n<section style=\"margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;text-align: center;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: Calibri;font-variant: normal;text-transform: none;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100015170\" data-ratio=\"0.8415094339622642\" data-src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/01717257629.png?resize=442%2C372\" data-type=\"png\" data-w=\"1060\" height=\"372 .3399658203125\" width=\"442 .47003173828125\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/01717257629.png?resize=442%2C372\"  data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;\">\u6837\u672c\u88ab\u6295\u5f71\u5230\u7531\u524d\u4e24\u4e2a\u4e3b\u6210\u5206\u8de8\u8d8a\u7684\u7a7a\u95f4\u4e2d\uff0c\u5e76\u6839\u636e\u7ec6\u80de\u7cfb\u7c7b\u578b\u7740\u8272\u3002\u6570\u5b57\u8868\u793a\u6570\u636e\u7684\u884c\u540d\u79f0\u3002\u6211\u4eec\u4e5f\u53ef\u4ee5\u8fdb\u4e00\u6b65\u68c0\u67e5\u7b2c\u4e09\u4e2a\u4e3b\u6210\u5206\uff0c\u53ea\u9700\u4fee\u6539<\/span><span style=\"line-height: 150%;font-family: &quot;Times New Roman Regular&quot;;font-variant: normal;text-transform: none;color: rgb(255, 0, 0);font-weight: normal;\">comp = c(1, 3)<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;\">\u5373\u53ef\uff0c\u6216\u8005\u4f7f\u75283D\u4ea4\u4e92\u56fe\uff0c\u4ee3\u7801\u5982\u4e0b\uff1a<\/span><\/span><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"php\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\"># \u4ea4\u4e92\u5f0f3D\u7ed8\u56fe\u5c06\u52a0\u8f7drgl\u5e93.<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">plotIndiv(final.pca.multi, style = '3d',<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">           group = multidrug$cell.line$Class,<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">          title = 'ABC transporters, PCA comp 1 - 3')<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;text-indent: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><br  \/><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">\u5927\u5bb6\u505a\u8fc7\u7b2c\u4e09\u4e2a\u4e3b\u6210\u5206\u7ed8\u56fe\u540e\u53ef\u53d1\u73b0\uff0c\u524d\u4e24\u4e2a\u5206\u91cf\u89e3\u91ca\u7684\u6700\u5927\u53d8\u5f02\u6e90\u53ef\u5f52\u56e0\u4e8e\u9ed1\u8272\u7d20\u7624\u7ec6\u80de\u7cfb\uff08MELAN\uff09\uff0c\u7b2c\u4e09\u4e2a\u5206\u91cf\u53ea\u7a81\u51fa\u663e\u793a\u4e86\u5355\u4e2a\u5f02\u5e38\u6837\u672c\u3002\u56e0\u6b64\uff0c\u5bf9\u6570\u636e\u7684\u89e3\u91ca\u4e3b\u8981\u96c6\u4e2d\u5728\u524d\u4e24\u4e2a\u4e3b\u6210\u5206\u3002<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: &quot;Times New Roman Regular&quot;;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;font-size: 16px;\">3.2.5\u53d8\u91cf\u56fe\uff1a\u76f8\u5173\u5706\u56fe<\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: windowtext;font-weight: normal;\">\u76f8\u5173\u5706\u56fe\u4f7f\u7528\u8be5\u51fd\u6570\u6307\u793a\u6bcf\u4e2a\u53d8\u91cf\u5bf9\u6bcf\u4e2a\u5206\u91cf\u7684\u8d21\u732eplotVar()\uff0c\u4ee5\u53ca\u53d8\u91cf\u4e4b\u95f4\u7684\u76f8\u5173\u6027\uff08\u7531\u53d8\u91cf\u201c\u7c07\u201d\u8868\u793a\uff09\u3002<\/span> &nbsp; &nbsp;<\/span><o:page><\/o:page><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"php\"><section style=\"text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">plotVar(final.pca.multi, comp = c(1, 2),var.names = TRUE,        cex = 3,         # To change the font size# cutoff = 0.5,  # For further cutoff        title = 'Multidrug transporter, PCA comp 1 - 2')<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;text-indent: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><br  \/><\/section>\n<section style=\"margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;text-align: center;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: Calibri;font-variant: normal;text-transform: none;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100015173\" data-ratio=\"0.8339552238805971\" data-src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/91717257630.png?resize=430%2C358\" data-type=\"png\" data-w=\"1072\" height=\"358 .739990234375\" width=\"430 .1400451660156\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/91717257630.png?resize=430%2C358\"  data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\"> &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;<o:p>&nbsp;<\/o:p><\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">\u56fe\u4e2d\u7a81\u51fa\u663e\u793a\u4e86\u4e00\u7ec4\u5bf9PC1\u6709\u8d21\u732e\u7684ABC\u8f6c\u8fd0\u86cb\u767d\uff1aABCE1\uff0c\u5e76\u4e14\u5728\u67d0\u79cd\u7a0b\u5ea6\u4e0a\u4e0eABCB8\u805a\u96c6\u7684\u7ec4\u5bf9PC1\u6709\u6b63\u5411\u8d21\u732e\uff0c\u800cABCA8\u6709\u8d1f\u5411\u8d21\u732e\u3002\u6211\u4eec\u8fd8\u89c2\u5bdf\u5230\u4e00\u7ec4\u5bf9 PC1 \u548c PC2 \u90fd\u6709\u8d21\u732e\u7684\u8f6c\u8fd0\u86cb\u767d\uff1a\u4e0eABCC2\u805a\u96c6\u7684\u4e00\u7ec4\u5bf9 PC2 \u6709\u6b63\u5411\u8d21\u732e\uff0c\u5bf9 PC1 \u6709\u8d1f\u5411\u8d21\u732e\uff0c\u800cABCC12\u548cABCD2\u7c07\u5bf9 PC1 \u548c PC2 \u90fd\u6709\u8d1f\u5411\u8d21\u732e\u3002<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">3.2.6 <\/span><span style=\"line-height: 150%;font-family: &quot;Times New Roman Regular&quot;;font-variant: normal;text-transform: none;font-weight: normal;\">Biplot\uff1a<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">\u6837\u672c\u548c\u53d8\u91cf<\/span><\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">\u53cc\u56fe\u5141\u8bb8\u6211\u4eec\u540c\u65f6\u663e\u793a\u6837\u672c\u548c\u53d8\u91cf\uff0c\u4ee5\u8fdb\u4e00\u6b65\u4e86\u89e3\u5b83\u4eec\u7684\u5173\u7cfb\u3002\u6837\u672c\u663e\u793a\u4e3a\u70b9\uff0c\u800c\u53d8\u91cf\u663e\u793a\u5728\u7bad\u5934\u7684\u5c16\u7aef\u3002\u4e0e\u76f8\u5173\u5706\u56fe\u7c7b\u4f3c\uff0c\u6570\u636e\u5fc5\u987b\u5c45\u4e2d\u5e76\u7f29\u653e\u4ee5\u89e3\u91ca\u53d8\u91cf\u4e4b\u95f4\u7684\u76f8\u5173\u6027\uff08\u4f5c\u4e3a\u53d8\u91cf\u7bad\u5934\u4e4b\u95f4\u7684\u4f59\u5f26\u89d2\uff09\u3002<\/span>&nbsp; &nbsp;&nbsp;<\/span><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"php\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">biplot(final.pca.multi, group = multidrug$cell.line$Class,<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">       legend.title = 'Cell line')<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;text-indent: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><br  \/><\/section>\n<section style=\"margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;text-align: center;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: Calibri;font-variant: normal;text-transform: none;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100015174\" data-ratio=\"0.8403263403263403\" data-src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/11717257631.png?resize=374%2C314\" data-type=\"png\" data-w=\"858\" height=\"314 .60003662109375\" width=\"374 .53997802734375\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/11717257631.png?resize=374%2C314\"  data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">Biplot\u663e\u793a\uff0c\u9ed1\u8272\u7d20\u7624\u7ec6\u80de\u7cfb\uff08<\/span><span style=\"line-height: 150%;font-family: &quot;Times New Roman Regular&quot;;font-variant: normal;text-transform: none;font-weight: normal;\">MELAN<\/span><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">\uff09\u4f3c\u4e4e\u4ee5\u8f6c\u8fd0\u86cb\u767d\u5b50\u96c6\u4e3a\u7279\u5f81\uff0c\u4f8b\u5982ABCC2\u5468\u56f4\u7684\u7c07\uff0c\u5982\u4e4b\u524d\u5728\u6837\u672c\u56fe\u4e2d\u7a81\u51fa\u663e\u793a\u7684\u90a3\u6837\u3002\u8fdb\u4e00\u6b65\u68c0\u67e5\u6570\u636e\uff0c\u4f8b\u5982\u7bb1\u7ebf\u56fe\uff0c\u53ef\u4ee5\u8fdb\u4e00\u6b65\u9610\u660e\u8fd9\u4e9b\u7279\u5b9a\u6837\u672c\u7684\u8f6c\u8fd0\u86cb\u767d\u8868\u8fbe\u6c34\u5e73\u3002<\/span><\/span><\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"php\"><section style=\"line-height: 1.6em;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">ABCC2.scale &lt;- scale(X[, 'ABCC2'], center = TRUE, scale = TRUE)<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">boxplot(ABCC2.scale ~<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">        multidrug$cell.line$Class, col = color.mixo(1:9),<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">        xlab = 'Cell lines', ylab = 'Expression levels, scaled',<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">        par(cex.axis = 0.5), # Font size<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span style=\"font-size: 16px;\">        main = 'ABCC2 transporter')<\/span><\/span><\/code><\/section><\/pre>\n<\/section>\n<section style=\"text-align: justify;margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><o:page><\/o:page><\/section>\n<section style=\"margin-left: 0pt;font-size: 12pt;font-family: Calibri;font-weight: normal;text-align: center;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: Calibri;font-variant: normal;text-transform: none;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100015175\" data-ratio=\"0.8201160541586073\" data-src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/81717257631.png?resize=343%2C281\" data-type=\"png\" data-w=\"1034\" height=\"281 .8699951171875\" width=\"343 .6700439453125\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/81717257631.png?resize=343%2C281\"  data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">\u4ecePCA\u76f8\u5173\u5706\u56fe\u548cBiplot\u9274\u5b9a\u7684\u8f6c\u8fd0\u86cb\u767dABCC2\u7684\u7bb1\u7ebf\u56fe\u663e\u793a\u4e0e\u7ec6\u80de\u7cfb\u7c7b\u578b\u76f8\u5173\u7684ABCC2\u8868\u8fbe\u6c34\u5e73\u3002<\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;font-size: 16px;\">\u4eca\u5929\u5c0f\u679c\u7ed9\u5927\u5bb6\u5c55\u793a\u7684\u662fmixOmics\u5305\u7684\u5b89\u88c5\uff0c\u5feb\u901f\u4f7f\u7528\u4ee5\u53caPCA\u7684\u793a\u4f8b\u5206\u6790\u3002\u5927\u5bb6\u53ef\u4ee5\u5728\u81ea\u5df1\u7684\u7ec4\u5b66\u6570\u636e\u4e0a\u8fdb\u884c\u5c1d\u8bd5\uff0c\u4eca\u5929\u53ea\u7ed9\u5927\u5bb6\u5c55\u793a\u4e86\u5355\u4e00\u7ec4\u5b66PCA\u7684\u793a\u4f8b\u5206\u6790\uff0c\u5927\u5bb6\u5982\u679c\u5bf9\u5176\u4ed6\u4e24\u79cd\u6a21\u5f0f\u5206\u6790\u6709\u5174\u8da3\u7684\u8bdd\uff0c\u53ef\u4ee5\u767b\u9646\u8be5R\u5305\u7684\u5b98\u65b9\u6587\u6863\u6216\u8005\u539f\u59cb\u6587\u732e\u518d\u8be6\u7ec6\u7814\u7a76\u4e00\u4e0b\u54e6\uff5e<\/span><\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 176, 80);font-weight: normal;\">\u5982\u679c\u9700\u8981\u6211\u4eec\u5e2e\u5fd9\u6765\u590d\u73b0\u8be5\u7bc7\u6587\u732e\u6216\u8005\u5206\u6790\u81ea\u5df1\u7684\u6570\u636e\u90fd\u53ef\u4ee5\u6765\u627e\u5c0f\u679c\u54e6\uff01\u4eca\u5929\u5c0f\u679c\u7684\u5206\u4eab\u5c31\u5230\u8fd9\u91cc\uff0c\u5982\u679c\u5c0f\u4f19\u4f34\u6709\u5176\u4ed6\u6570\u636e\u7684\u5206\u6790\u9700\u6c42\uff0c\u53ef\u4ee5\u5c1d\u8bd5\u672c\u516c\u53f8\u65b0\u5f00\u53d1\u7684\u751f\u4fe1\u5206\u6790\u5c0f\u5de5\u5177\u4e91\u54c1\u53f0\uff0c\u91cc\u9762\u6709\u6210\u719f\u7684\u4ee3\u7801\uff0c\u53ea\u8981\u8f93\u5165\u5408\u9002\u7684\u6570\u636e\u5c31\u53ef\u4ee5\u76f4\u63a5\u51fa\u60f3\u8981\u7684\u56fe\u5462\uff0c\u94fe\u63a5\uff1a<\/span><span style=\"font-family: &quot;Times New Roman Regular&quot;;font-variant: normal;text-transform: none;color: rgb(0, 176, 80);font-weight: 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0.9);\">\u63d0\u4f9b\u601d\u8def\u8bbe\u8ba1\u3001\u5b9a\u5236\u751f\u4fe1\u5206\u6790\u3001\u6587\u732e\u601d\u8def\u590d\u73b0\uff1b\u6709\u9700\u8981\u7684\u5c0f\u4f19\u4f34\u6b22\u8fce\u76f4\u63a5\u626b\u7801\u54a8\u8be2\u5c0f\u679c\uff0c\u7aed\u8bda\u4e3a\u60a8\u7684\u79d1\u7814\u52a9\u529b\uff01<\/span><\/span><\/strong><\/span><\/p>\n<p style=\"margin-bottom: 0px;\"><br  \/><\/p>\n<section style=\"font-size: 15px;padding-right: 2px;padding-left: 2px;margin-bottom: 0px;\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;flex: 0 0 auto;height: auto;border-color: rgb(114, 114, 114);border-width: 1px;border-style: solid;box-shadow: rgb(194, 209, 255) -5px 5px 0px;align-self: flex-start;\">\n<section style=\"justify-content: center;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 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style=\"line-height: 2;letter-spacing: 1px;color: rgb(43, 65, 110);\" powered-by=\"xiumi.us\">\n<p style=\"margin-bottom: 2px;\"><strong>\u5b9a\u5236\u751f\u4fe1\u5206\u6790<\/strong><\/p>\n<p style=\"margin-bottom: 2px;\"><strong>\u670d\u52a1\u5668\u79df\u8d41<\/strong><\/p>\n<p><strong>\u626b\u7801\u54a8\u8be2\u5c0f\u679c<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-wrap: wrap;\" powered-by=\"xiumi.us\"><br  \/><\/p>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&amp;mid=2247497780&amp;idx=2&amp;sn=7eee90af6f387e4153bba13028e545a1&amp;chksm=cf7f68f1f808e1e7dfb3a0597ef442e5c6e700ecf6ee5a035c766a4c7486c12eabd0ab218ea6&amp;scene=21#wechat_redirect\" textvalue=\"\u4f60\u5df2\u9009\u4e2d\u4e86\u6dfb\u52a0\u94fe\u63a5\u7684\u5185\u5bb9\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"1\" rel=\"noopener\"><span class=\"js_jump_icon h5_image_link\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-imgfileid=\"100018621\" data-ratio=\"0.3253333333333333\" data-s=\"300,640\" data-src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/21717257632.png?w=640\" data-type=\"png\" data-w=\"750\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/21717257632.png?w=640\"  data-recalc-dims=\"1\" \/><\/span><\/a><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\"><br  \/><\/section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;text-align: left;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-end;padding-right: 2px;padding-left: 2px;\">\n<section style=\"margin: 10px 0% 2px;transform: translate3d(2px, 0px, 0px);\" powered-by=\"xiumi.us\">\n<section style=\"font-size: 16px;color: rgb(58, 66, 94);line-height: 1;letter-spacing: 5px;text-align: center;\">\n<p><strong>\u5f80\u671f\u56de\u987e<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"height: 3px;background-color: rgb(95, 156, 239);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<section style=\"margin-top: 2px;margin-right: 0%;margin-left: 0%;text-align: center;line-height: 0.8;font-size: 9px;\" powered-by=\"xiumi.us\">\n<section style=\"width: 0px;display: inline-block;border-top: 0.8em solid rgb(58, 66, 94);border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;flex: 100 100 0%;align-self: flex-end;height: auto;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"height: 3px;background-color: rgb(95, 156, 239);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<section style=\"margin-top: 2px;margin-right: 0%;margin-left: 0%;text-align: center;line-height: 0.8;font-size: 9px;\" powered-by=\"xiumi.us\">\n<section style=\"width: 0px;display: inline-block;border-top: 0.8em solid rgba(255, 255, 255, 0);border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"min-height: 40px;margin: 10px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"width: 100%;margin-right: auto;margin-bottom: -10px;margin-left: auto;\">\n<table width=\"100%\">\n<tbody>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:0\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:0.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>01<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&amp;mid=2247497780&amp;idx=2&amp;sn=7eee90af6f387e4153bba13028e545a1&amp;chksm=cf7f68f1f808e1e7dfb3a0597ef442e5c6e700ecf6ee5a035c766a4c7486c12eabd0ab218ea6&amp;scene=21#wechat_redirect\" textvalue=\"1024G\u5b58\u50a8\u7684\u751f\u4fe1\u670d\u52a1\u5668\uff0c\u4e24\u4eba\u6210\u56e2\uff0c1\u4eba\u514d\u5355\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">1024G\u5b58\u50a8\u7684\u751f\u4fe1\u670d\u52a1\u5668\uff0c\u4e24\u4eba\u6210\u56e2\uff0c1\u4eba\u514d\u5355\uff01<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:1\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:1.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>02<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&amp;mid=2247498878&amp;idx=1&amp;sn=fc34ed3f1d15d060bbaf8166adcebd58&amp;chksm=cf7f6cbbf808e5ad0b5417e50ed75cfbd1b3a83ac43b97f1dfa718c822878a9a004990075133&amp;scene=21#wechat_redirect\" textvalue=\"\u5355\u4e2a\u6570\u636e\u5e93\u7528\u817b\u4e86\uff1f\u591a\u6570\u636e\u5e93\u201c\u7ec4\u5408\u62f3\u201d\u5e26\u4f60\u6253\u5f00\u514d\u75ab\u6d78\u6da6\u65b0\u601d\u8def\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u5355\u4e2a\u6570\u636e\u5e93\u7528\u817b\u4e86\uff1f\u591a\u6570\u636e\u5e93\u201c\u7ec4\u5408\u62f3\u201d\u5e26\u4f60\u6253\u5f00\u514d\u75ab\u6d78\u6da6\u65b0\u601d\u8def\uff01<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:2\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:2.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>03<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&amp;mid=2247498673&amp;idx=1&amp;sn=1e09b74a836c1e64a62ae1f66eeb3f93&amp;chksm=cf7f6b74f808e262de70be43fd73bf5fefdc0914e525eb2032f741a0152e619689cedc76946f&amp;scene=21#wechat_redirect\" textvalue=\"\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u7684\u51c6\u5907\u5de5\u4f5c\uff0cGWAS\u6570\u636e\u7684\u7f51\u7ad9\u4e0b\u8f7d\u65b9\u6cd5\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"11\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u7684\u51c6\u5907\u5de5\u4f5c\uff0cGWAS\u6570\u636e\u7684\u7f51\u7ad9\u4e0b\u8f7d\u65b9\u6cd5<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:3\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:3.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>04<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&amp;mid=2247498517&amp;idx=1&amp;sn=fa3c0104cee316982fe8162b79fe234f&amp;chksm=cf7f6bd0f808e2c6cf979704bf883cfb5480444604f90da61dc286e7541fa5bb49df0a2fb58a&amp;scene=21#wechat_redirect\" textvalue=\"\u8ddf\u7740\u5c0f\u679c\u5b66\u590d\u73b0-\u624b\u628a\u624b\u5e26\u4f60\u62ff\u4e0bIF=46.9Nature \u7ea7\u522b\u7684\u4e3b\u6210\u5206\u5206\u6790\uff08PCA\uff09\u56fe\uff01\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u8ddf\u7740\u5c0f\u679c\u5b66\u590d\u73b0-\u624b\u628a\u624b\u5e26\u4f60\u62ff\u4e0bIF=46.9Nature \u7ea7\u522b\u7684\u4e3b\u6210\u5206\u5206\u6790\uff08PCA\uff09\u56fe\uff01\uff01<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-bottom: 0px;\"><br  \/><\/p>\n<section style=\"text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><br  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: justify;font-size: 12pt;font-family: Calibri;font-weight: normal;margin-left: 0pt;break-before: auto;break-after: auto;word-break: normal;direction: ltr;line-height: 1.6em;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><o:page><\/o:page><\/section>\n<section style=\"text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\">\n<section style=\"display: none;text-align: justify;text-indent: 2em;\"><br  \/><\/section>\n<\/section>\n<p style=\"display: none;\"><mp-style-type data-value=\"3\"><\/mp-style-type><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6211\u4eec\u751f\u4fe1\u4eba\u5728\u505a\u5206\u6790\u7684\u65f6\u5019\uff0c\u5982\u679c\u9047\u5230\u7684\u662f\u5355\u4e00\u7c7b\u578b\u7684\u6570\u636e\uff0c\u5982\u7532\u57fa\u5316\u6570\u636e\uff0c\u8f6c\u5f55\u7ec4\u5b66\u6570\u636e\u3001\u4ee3\u8c22\u7ec4\u5b66\u6570\u636e\u7b49\uff0c\u6211\u4eec\u53ef\u80fd\u662f\u624b [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":43166,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/41717257620.jpg?fit=798%2C339","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/43165"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=43165"}],"version-history":[{"count":2,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/43165\/revisions"}],"predecessor-version":[{"id":43202,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/43165\/revisions\/43202"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/media\/43166"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=43165"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=43165"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=43165"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}