{"id":43476,"date":"2024-06-02T01:16:51","date_gmt":"2024-06-01T17:16:51","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=43476"},"modified":"2024-06-11T11:40:40","modified_gmt":"2024-06-11T03:40:40","slug":"555dadf0a2","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=43476","title":{"rendered":"Nature|\u91cd\u78c5\u63ed\u79d8\uff01\u574f\u6b7b\u578b\u51cb\u4ea1\u4e0e\u708e\u75c7\u5173\u7cfb\u5bc6\u5207\uff0c\u5176\u6291\u5236\u5242\u5e94\u7528\u524d\u666f\u5e7f\u9614\uff01"},"content":{"rendered":"
\n
<\/mp-common-profile><\/section>\n
\n
\n
\n
\u672c\u200d<\/span>\u6587\u8f6c\u8f7d\u4e8e\u516c\u4f17\u53f7\u201c\u79d1\u7814\u72ee\u201d\u2014\u2014\u81f4\u529b\u4e8e\u533b\u5b66\u76f8\u5173\u79d1\u7814\u53ca\u8bfe\u9898\u8bbe\u8ba1\u5de5\u4f5c<\/section>\n<\/section>\n<\/blockquote>\n<\/section>\n
\u563f\uff0c\u5927\u5bb6\u597d\uff0c\u6211\u662f\u4f60\u4eec\u7684\u5e08\u54e5\u3002\u4f60\u4eec\u6709\u6ca1\u6709\u60f3\u8fc7\uff0c\u6bcf\u5e74\u6d41\u611f\u5b63\u8282\u4e3a\u4ec0\u4e48\u4f1a\u6210\u4e3a\u8fd9\u4e48\u591a\u4eba\u7684\u5669\u68a6\uff1f\u6bcf\u5e74\u593a\u8d70\u6570\u767e\u4e07\u751f\u547d\u7684\u5168\u7403\u6d41\u611f\u5a01\u80c1\u65e5\u76ca\u52a0\u5267\u3002\u5728\u8fd9\u4e2a\u4e25\u5cfb\u7684\u6311\u6218\u9762\u524d\uff0c\u5e08\u54e5\u5206\u4eab\u7684\u8fd9\u7bc7nature\u7684\u6700\u65b0\u7814\u7a76\u63d0\u4f9b\u4e86\u4e00\u4e2a\u53ef\u80fd\u7684\u6cbb\u7597\u65b9\u5411\uff01\u672c\u7814\u7a76\u901a\u8fc7\u5e72\u9884\u574f\u6b7b\u6837\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea1\uff0c\u53ef\u4ee5\u6709\u6548\u9884\u9632\u4e25\u91cd\u6d41\u611f\u5f15\u8d77\u7684\u80ba\u635f\u4f24\uff0c\u4e3a\u6cbb\u7597\u6d41\u611f\u548c\u76f8\u5173\u75be\u75c5\u63d0\u4f9b\u4e86\u65b0\u7684\u601d\u8def\u548c\u65b9\u6cd5\uff1a<\/span><\/section>\n
1.\u672c\u6587\u7814\u7a76\u80cc\u666f\u548c\u7814\u7a76\u5bf9\u8c61\u4e3a<\/span>\u6d41\u611f\u548c\u574f\u6b7b<\/span>\uff0c\u5c5e\u4e8e\u7ecf\u5178\u7684\u7814\u7a76\u4e2d\u5bfb\u627e\u521b\u65b0\u3002<\/span>\u574f\u6b7b\u578b\u51cb\u4ea1\uff08necroptosis\uff09<\/span>\u662f\u4e00\u79cd\u975e\u5178\u578b\u7684\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea1\u5f62\u5f0f\uff0c\u901a\u5e38\u5728\u7ec6\u80de\u53d7\u5230\u4e25\u91cd\u635f\u4f24\u6216\u75be\u75c5\u6761\u4ef6\u4e0b\u53d1\u751f\u3002\u4e0e\u4f20\u7edf\u7684\u51cb\u4ea1\u4e0d\u540c\uff0c\u574f\u6b7b\u578b\u51cb\u4ea1\u901a\u5e38\u4f34\u968f\u7740\u7ec6\u80de\u5185\u7684\u708e\u75c7\u53cd\u5e94\uff0c\u4ee5\u53ca\u7ec6\u80de\u819c\u7684\u7834\u88c2\u548c\u6eb6\u89e3\u3002\u8fd9\u79cd\u5f62\u5f0f\u7684\u7ec6\u80de\u6b7b\u4ea1\u88ab\u8ba4\u4e3a\u5728\u514d\u75ab\u5e94\u7b54\u3001\u53d1\u80b2\u548c\u75be\u75c5\u53d1\u751f\u4e2d\u8d77\u7740\u91cd\u8981\u4f5c\u7528\uff1b<\/span><\/span><\/section>\n
2.<\/span>\u672c\u7814\u7a76\u53d1\u73b0\u4e00\u4e2a\u65b0\u7684<\/span>RIPK3\u6fc0\u9176\u6291\u5236\u5242UH15-38<\/span>\uff0c\u4e3b\u8981\u901a\u8fc7\u7814\u7a76UH15-38\u5bf9\u574f\u6b7b\u53ca\u80ba\u635f\u4f24\u7684\u5f71\u54cd\uff0c\u5e76\u5bf9\u5176\u673a\u5236\u8fdb\u884c\u6df1\u5165\u7814\u7a76\uff0c\u4ece\u800c\u9a8c\u8bc1\u4e86\u9488\u5bf9\u8fd9\u4e00\u7ec6\u80de\u6b7b\u4ea1\u9014\u5f84\u7684\u5e72\u9884\u53ef\u4ee5\u6210\u4e3a\u6cbb\u7597\u4e25\u91cd\u6d41\u611f\u5f15\u8d77\u7684\u80ba\u90e8\u635f\u4f24\u7684\u6709\u6548\u7b56\u7565\u3002\u60f3\u8981\u53d1\u8868\u9ad8\u5206SCI\u7684\u5c0f\u4f19\u4f34\u4eec\u4e5f\u53ef\u4ee5\u501f\u9274\u4e00\u4e0b\u672c\u6587\u7684\u7814\u7a76\u601d\u8def\u54e6<\/span>~<\/span>(ps\uff1a\u7f3a\u4e4f\u65b0\u7684\u65b9\u6848\u601d\u8def\uff1f\u65b9\u6848\u8bbe\u8ba1\u6709\u56f0\u96be\uff1f\u5feb\u6765\u79d1\u7814\u72ee<\/span>\u8fd9\u91cc\u591a\u5b66\u4e60\uff01\u70b9\u51fb\u540d\u7247\u5173\u6ce8\u79d1\u7814\u72ee\uff0c\u4e3a\u60a8\u89e3\u51b3\u70e6\u607c\uff01)<\/span> <\/span><\/span><\/span><\/section>\n
<\/mp-common-profile><\/section>\n
<\/o:page><\/section>\n
\"Nature|\u91cd\u78c5\u63ed\u79d8\uff01\u574f\u6b7b\u578b\u51cb\u4ea1\u4e0e\u708e\u75c7\u5173\u7cfb\u5bc6\u5207\uff0c\u5176\u6291\u5236\u5242\u5e94\u7528\u524d\u666f\u5e7f\u9614\uff01\"<\/span><\/section>\n

\u9898\u76ee\uff1a\u963b\u65ad\u574f\u6b7b\u7a0b\u5e8f\u6b7b\u4ea1\u53ef\u9884\u9632\u91cd\u578b\u6d41\u611f\u5f15\u8d77\u7684\u80ba\u635f\u4f24<\/span><\/p>\n

\u6742\u5fd7\uff1aNature<\/span><\/p>\n

\u5f71\u54cd\u56e0\u5b50\uff1aIF=64.8<\/span><\/p>\n

\u53d1\u8868\u65f6\u95f4\uff1a2024\u5e744\u6708<\/span><\/section>\n
\u7814\u7a76\u80cc\u666f<\/span><\/section>\n
\u5b63\u8282\u6027\u6d41\u611f\u75c5\u6bd2\u611f\u67d3\u6bcf\u5e74\u5728\u5168\u7403\u9020\u6210\u9ad8\u8fbe500\u4e07\u4f8b\u4e25\u91cd\u75be\u75c5\uff0c\u5e76\u5bfc\u81f4\u591a\u8fbe65\u4e07\u4eba\u6b7b\u4ea1\u3002\u7531\u4e8e\u5f53\u524d\u7684\u75ab\u82d7\u548c\u6297\u75c5\u6bd2\u7b56\u7565\u5728\u6548\u529b\u4e0a\u53d7\u9650\uff0c\u6216\u6613\u53d7\u75c5\u6bd2\u8010\u836f\u6027\u548c\u9003\u9038\u7684\u5f71\u54cd\uff0c\u56e0\u6b64\u5fc5\u987b\u786e\u5b9a\u9488\u5bf9\u75c5\u6bd2\u6027\u6d41\u611f\u5f15\u53d1\u7684\u80ba\u90e8\u75be\u75c5\u7684\u65b0\u6cbb\u7597\u65b9\u6cd5\u3002IAV\uff08Influenza A Virus\uff09\u5f15\u53d1\u7684\u7ec6\u80de\u6b7b\u4ea1\u53ef\u80fd\u5176\u81f4\u75c5\u539f\u56e0\u4e4b\u4e00\uff0c\u5f53\u8fd9\u79cd\u6b7b\u4ea1\u5f97\u5230\u826f\u597d\u63a7\u5236\u65f6\uff0c\u5b83\u662f\u4e00\u79cd\u6709\u6548\u7684\u75c5\u6bd2\u6e05\u9664\u673a\u5236\uff0c\u4f46\u5f53\u6b7b\u4ea1\u4e0d\u53d7\u63a7\u5236\u6216\u4e3b\u8981\u4e3a\u574f\u6b7b\u65f6\uff0c\u5c3d\u7ba1\u75c5\u6bd2\u88ab\u6e05\u9664\uff0c\u80ba\u635f\u4f24\u548c\u4e25\u91cd\u75be\u75c5\u4ecd\u4f1a\u53d1\u751f\u3002<\/span><\/section>\n
\u7814\u7a76\u601d\u8def<\/span><\/section>\n
Necroptosis\u5728IAV\u611f\u67d3\u7684\u80ba\u4e0a\u76ae\u7ec6\u80de\u4e2d\u662f\u4e3b\u8981\u7684\u7a0b\u5e8f\u6027\u6b7b\u4ea1\u65b9\u5f0f\uff0c\u5728\u4e25\u91cd\u7684\u611f\u67d3\u4e2d\u4f1a\u5bfc\u81f4\u80ba\u7ec4\u7ec7\u574f\u6b7b\u3001\u4e2d\u6027\u7c92\u7ec6\u80de\u805a\u96c6\u548c\u80ba\u90e8\u708e\u75c7\u3002\u7136\u800c\uff0c\u5b83\u5bf9CD8+ T\u7ec6\u80de\u7684\u6297\u75c5\u6bd2\u53cd\u5e94\u6216\u75c5\u6bd2\u6e05\u9664\u5e76\u4e0d\u91cd\u8981\u3002RIPK3\u6fc0\u6d3b\u4e86\u53e6\u4e00\u6761\u51cb\u4ea1\u9014\u5f84Apoptosis\uff0c\u4e0d\u4f9d\u8d56\u4e8eRIPK3\u7684\u6fc0\u9176\u6d3b\u6027\uff0c\u53ef\u4ee5\u5728necroptosis\u4fe1\u53f7\u7f3a\u5931\u65f6\u9650\u5236IAV\uff08\u56fe1a\uff09\u3002\u56e0\u6b64\uff0c\u6291\u5236RIPK3\u6fc0\u9176\u6d3b\u6027\u53ef\u80fd\u662f\u4e00\u79cd\u6cbb\u7597\u7b56\u7565\uff0c\u53ef\u4ee5\u51cf\u8f7b\u574f\u6b7b\u6027\u80ba\u635f\u4f24\uff0c\u800c\u4e0d\u5f71\u54cd\u75c5\u6bd2\u6e05\u9664\u3002<\/span>(ps\uff1a\u9ad8\u5206\u6587\u7ae0\u4e4b\u6240\u4ee5\u5f15\u4eba\u6ce8\u76ee\uff0c\u4e43\u56e0\u5176\u903b\u8f91\u6e05\u6670\uff0c\u4ece\u4e00\u5f00\u59cb\u5c31\u5411\u8bfb\u8005\u660e\u786e\u4e86\u6838\u5fc3\u601d\u8def\u3002\u968f\u540e\uff0c\u56f4\u7ed5\u8fd9\u4e00\u6838\u5fc3\uff0c\u4f5c\u8005\u5bf9PIPK3\u6fc0\u9176\u6d3b\u6027\u5c55\u5f00\u9a8c\u8bc1\u3002\u8ba9\u6211\u4eec\u4e00\u540c\u5b66\u4e60\u8fd9\u79cd\u7b80\u6d01\u800c\u53c8\u9ad8\u6548\u7684\u8868\u8fbe\u65b9\u5f0f\u5427\uff01)<\/span> <\/span><\/o:page><\/section>\n
\"Nature|\u91cd\u78c5\u63ed\u79d8\uff01\u574f\u6b7b\u578b\u51cb\u4ea1\u4e0e\u708e\u75c7\u5173\u7cfb\u5bc6\u5207\uff0c\u5176\u6291\u5236\u5242\u5e94\u7528\u524d\u666f\u5e7f\u9614\uff01\"<\/span><\/section>\n
\u4e3b\u8981\u7ed3\u679c<\/span><\/section>\n
1. UH15-38\u662f\u4e00\u79cd\u5f3a\u6548RIPK3\u6fc0\u9176\u6291\u5236\u5242<\/span><\/section>\n
\u7814\u7a76\u53d1\u73b0\uff0c\u7f3a\u4e4fnecroptosis\u7684\u5c0f\u9f20\u5728\u4e25\u91cd\u6d41\u611f\u611f\u67d3\u540e\u6709\u66f4\u9ad8\u7684\u5b58\u6d3b\u7387<\/span>\uff0c\u53ef\u89c1necroptosis\u4e0d\u4ec5\u4e0d\u662f\u5c0f\u9f20\u5b58\u6d3b\u6216\u75c5\u6bd2\u6e05\u9664\u6240\u5fc5\u9700\u7684\uff0c\u800c\u4e14\u5b9e\u9645\u4e0a\u5728IAV\u81f4\u6b7b\u5242\u91cf\u4e0b\u5bf9\u751f\u5b58\u662f\u6709\u5bb3\u7684<\/span>\uff08\u56fe1b\uff09<\/span>\u3002<\/span>\u63a5\u4e0b\u6765\u4f5c\u8005\u6839\u636e\u5148\u524d\u7684\u7814\u7a76\u5408\u6210\u4e8640\u591a\u4e2a\u5316\u5408\u7269\uff08RIPK3\u6291\u5236\u5242\uff09\uff0c\u6700\u7ec8\u53d1\u73b0<\/span>UH15-38<\/span>\uff08\u56fe1c\uff09\u5728\u539f\u5c0f\u9f20\u80da\u80ce\u6210\u7ea4\u7ef4\u7ec6\u80de\uff08MEFs\uff09\u4e2d\u963b\u65ad\u4e86TNF\u8bf1\u5bfc\u7684\u574f\u6b7b\u6027\u51cb\u4ea1\uff08\u56fe1d-f\uff09\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u5206\u5b50\u5bf9\u63a5\u7ed3\u679c\u663e\u793aUH15-38\u6b63\u662f\u5176<\/span>\u5bf9\u915a\u57fa\u7684\u7532\u57fa\u5316\uff0c\u5bfc\u81f4RIPK3\u7684\u6d3b\u6027\u4e27\u5931<\/span>\uff08\u56fe1g-i\uff09\u3002\u6b64\u5916\uff0c\u4f5c\u8005\u8fd8\u8fdb\u4e00\u6b65\u5168\u9762\u9a8c\u8bc1UH15-38\u5177\u6709\u9002\u5408\u5b89\u5168\u6709\u6548\u7684\u4f53\u5185\u5e94\u7528\u7684\u836f\u7406\u7279\u6027\u3002<\/span>\uff08<\/span>ps\uff1a\u8fd9\u91cc\u53ef\u4ee5\u770b\u5230\u4f5c\u8005\u5177\u6709\u4e25\u8c28\u7684\u79d1\u7814\u601d\u7ef4\uff0c\u5728\u521d\u6b65\u9a8c\u8bc1\u5176\u6709\u6548\u6027\u540e\uff0c\u4f5c\u8005\u9a6c\u4e0a\u8fdb\u884c\u5176\u751f\u7269\u5b89\u5168\u6027\u8bc4\u4f30\uff09<\/span><\/span><\/span><\/span><\/o:page><\/section>\n
\"Nature|\u91cd\u78c5\u63ed\u79d8\uff01\u574f\u6b7b\u578b\u51cb\u4ea1\u4e0e\u708e\u75c7\u5173\u7cfb\u5bc6\u5207\uff0c\u5176\u6291\u5236\u5242\u5e94\u7528\u524d\u666f\u5e7f\u9614\uff01\"<\/span><\/section>\n
\u56fe1 UH15-38\u662f\u4e00\u79cd\u5f3a\u6548RIPK3\u6fc0\u9176\u6291\u5236\u5242<\/span><\/section>\n
2. UH15-38\u963b\u65ad\u4e86IAV\u6fc0\u6d3b\u7684\u7a0b\u5e8f\u6027\u574f\u6b7b<\/span><\/section>\n
\u4f5c\u8005\u901a\u8fc7\u5355\u7ec6\u80deRNA\u6d4b\u5e8f\u5206\u6790\uff0c<\/span>\u786e\u5b9a\u4e86I\u578b\u80ba\u6ce1\u4e0a\u76ae\u7ec6\u80de\uff08ACEs\uff09\u4f5c\u4e3a\u5c0f\u9f20\u80ba\u4e2dIAV\u7684\u4e3b\u8981\u590d\u5236\u4f4d\u70b9<\/span>\uff08\u56fe2a-c\uff09<\/span>\u3002<\/span>\u56fe2d-e\u7ed3\u679c\u663e\u793a\u611f\u67d3IAV\u540e\uff0cI\u578bAECs\u5177\u6709\u5b8c\u6574\u7684ZBP1\u4f9d\u8d56\u6027\u7684\u7ec6\u80de\u6b7b\u4ea1\u673a\u5236\uff0c\u5305\u62ec\u574f\u6b7b\u548c\u51cb\u4ea1\u3002\u6b64\u5916\uff0c\u4f5c\u8005\u9a8c\u8bc1<\/span>UH15-38\u5bf9IAV\u8bf1\u5bfc\u7684\u574f\u6b7b\u5177\u6709<\/span>\u9ad8\u5ea6\u9009\u62e9\u6027<\/span>\u7684\u6291\u5236\u4f5c\u7528\uff0c\u5bf9caspase\u4ecb\u5bfc\u7684\u51cb\u4ea1\u6ca1\u6709\u6291\u5236\u4f5c\u7528<\/span>\uff08\u56fe2f-h\uff09\u3002\u503c\u5f97\u7279\u522b\u5173\u6ce8\u7684\u662f\uff0c<\/span>UH15-38\u5728\u4f53\u5916\u611f\u67d3IAV\u7684\u4eba\u7c7b\u4f9b\u4f53\u80ba\u7ec4\u7ec7\u4e2d\u5b8c\u5168\u6291\u5236\u4e86MLKL\u7684\u78f7\u9178\u5316<\/span>\uff0c\u8868\u660eUH15-38\u662f\u5c0f\u9f20\u548c\u4eba\u7c7b\u7ec6\u80de\u4e2dIAV\u8bf1\u5bfc\u7684\u574f\u6b7b\u7684<\/span>\u5f3a\u6548\u800c\u7279\u5f02<\/span>\u7684\u6291\u5236\u5242\uff08\u56fe2i-l\uff09\u3002<\/span><\/span><\/o:page><\/section>\n
\"Nature|\u91cd\u78c5\u63ed\u79d8\uff01\u574f\u6b7b\u578b\u51cb\u4ea1\u4e0e\u708e\u75c7\u5173\u7cfb\u5bc6\u5207\uff0c\u5176\u6291\u5236\u5242\u5e94\u7528\u524d\u666f\u5e7f\u9614\uff01\" <\/span><\/section>\n
\u56fe2 UH15-38\u53ef\u9009\u62e9\u6027\u963b\u65adIAV\u8bf1\u5bfc\u7684I\u578bAECs\u7a0b\u5e8f\u6027\u574f\u6b7b<\/span><\/section>\n
3. UH15-38\u53ef\u9632\u6b62IAV\u9a71\u52a8\u7684\u6b7b\u4ea1<\/span><\/section>\n
\u4f5c\u8005\u53d1\u73b0UH15-38\u5bf9IAV\u8bf1\u5bfc\u7684\u6b7b\u4ea1\u7684\u6700\u5927\u4fdd\u62a4\u6548\u679c\u4e3a<\/span>30mg\/kg<\/span>\u5242\u91cf\uff08\u56fe3a\uff09\u3002\u5728IAV\uff084\uff0c500\u00d7EID50<\/sub>\u7b26\u5408\u4e34\u5e8a\u7684\u5242\u91cf\uff09\u611f\u67d3\u65f6\uff0c<\/span>\u4f4e\u81f31mg\/kg\u7684UH15-38\u4ecd\u80fd\u5b8c\u5168\u9884\u9632\u611f\u67d3<\/span>\uff08\u56fe3c\uff09\u3002UH15-38\u8fd8\u80fd\u591f\u5b8c\u5168\u9884\u9632\u53c8H1N1 A\/California\/04\/2009\u6d41\u611f\u75c5\u6bd2\u682a\u5f15\u53d1\u7684\u81f4\u6b7b\uff08\u56fe3d\uff09\uff0c\u8868\u660e\u5176<\/span>\u5bf9\u5b63\u8282\u6027\u548c\u5927\u6d41\u884c\u6d41\u611f\u75c5\u6bd2\u682a\u7684\u6cbb\u7597\u6548\u76ca<\/span>\u3002\u5373\u4f7f\u5728\u611f\u67d3\u540e5\u5929\u5185\u7ed9\u4e88UH15-38\uff0c\u5b83\u4e5f\u80fd\u591f\u8d77\u5230\u4fdd\u62a4\u4f5c\u7528\uff08\u56fe3e\uff09\uff0c\u6bd4\u4e00\u7ebf\u6297\u75c5\u6bd2\u836f\u7269<\/span>\u5965\u53f8\u4ed6\u97e6<\/span>\u66f4\u5177\u6709\u4f18\u52bf\u3002<\/span><\/span><\/o:page><\/section>\n
\"Nature|\u91cd\u78c5\u63ed\u79d8\uff01\u574f\u6b7b\u578b\u51cb\u4ea1\u4e0e\u708e\u75c7\u5173\u7cfb\u5bc6\u5207\uff0c\u5176\u6291\u5236\u5242\u5e94\u7528\u524d\u666f\u5e7f\u9614\uff01\" <\/span><\/section>\n
\u56fe3 UH15-38\u53ef\u9884\u9632\u91cd\u75c7\u6d41\u611f\u5f15\u8d77\u7684\u6b7b\u4ea1<\/span><\/section>\n
4. UH15-38\u6291\u5236IAV\u8bf1\u5bfc\u7684\u80ba\u635f\u4f24<\/span><\/section>\n
\u63a5\u4e0b\u6765\u4f5c\u8005\u68c0\u9a8c30mg\/kg\u7684UH15-38\u662f\u5426\u80fd\u591f\u5728\u4f53\u5185\u963b\u65ad\u574f\u6b7b\u548c\u80ba\u635f\u4f24\u6765\u9884\u9632IAV\u8bf1\u5bfc\u7684\u6b7b\u4ea1\uff0c\u7ed3\u679c\u663e\u793aUH15-38\u5904\u7406\u540e\u5c0f\u9f20pMLKL\u7684\u6570\u91cf\u663e\u8457\u51cf\u5c11\uff08\u56fe4a-b\uff09\u3002\u6b64\u5916\uff0cUH15-38\u53ef\u4ee5\u663e\u8457\u964d\u4f4e\u5173\u952e\u708e\u6027\u56e0\u5b50\u548c\u4e2d\u6027\u7c92\u7ec6\u80de\u8d8b\u5316\u56e0\u5b50\u6c34\u5e73\uff08\u56fe4c-e\uff09\u3002\u63a5\u53d7UH15-38\u6cbb\u7597\u7684\u5c0f\u9f20\u80ba\u90e8\u5f25\u6f2b\u6027\u80ba\u6ce1\u635f\u4f24\u3001\u900f\u660e\u819c\u5f62\u6210\u663e\u8457\u51cf\u5c11\uff0c\u652f\u6c14\u7ba1\u8131\u5c42\u548c\u80ba\u7ea4\u7ef4\u5316\u4e5f\u663e\u8457\u88ab\u6291\u5236\uff08\u56fe4f-g\uff09\uff0c\u52a8\u8109\u6c27\u9971\u548c\u5ea6\u6c34\u5e73\u4fdd\u6301\u76f8\u5bf9\u6b63\u5e38\u7684\u80ba\u529f\u80fd\uff08\u56fe4h\uff09\u3002\u7efc\u4e0a\u6240\u8ff0\uff0c<\/span>UH15-38\u53ef\u4ee5\u663e\u8457\u964d\u4f4eIAV\u75c5\u6bd2\u5f15\u53d1\u7684\u80ba\u635f\u4f24\u7a0b\u5ea6<\/span>\u3002<\/span><\/span><\/o:page><\/section>\n
\"Nature|\u91cd\u78c5\u63ed\u79d8\uff01\u574f\u6b7b\u578b\u51cb\u4ea1\u4e0e\u708e\u75c7\u5173\u7cfb\u5bc6\u5207\uff0c\u5176\u6291\u5236\u5242\u5e94\u7528\u524d\u666f\u5e7f\u9614\uff01\"<\/span><\/section>\n
\u56fe4 UH15-38\u53ef\u9884\u9632IAV\u611f\u67d3\u80ba\u90e8\u7684\u574f\u6b7b\u6027\u51cb\u4ea1\u3001\u708e\u75c7\u548c\u635f\u4f24<\/span><\/section>\n
\u6587\u7ae0\u5c0f\u7ed3<\/span><\/section>\n
\u8fd9\u9879\u7814\u7a76\u53d1\u73b0\u901a\u8fc7\u963b\u65ad\u574f\u6b7b\u6837\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea1\uff0c\u53ef\u4ee5\u663e\u8457\u51cf\u8f7b\u4e25\u91cd\u6d41\u611f\u5f15\u8d77\u7684\u80ba\u90e8\u635f\u4f24\u3002\u8fd9\u4e00\u53d1\u73b0\u4e3a\u5f00\u53d1\u65b0\u578b\u6cbb\u7597\u7b56\u7565\u4ee5\u9632\u6cbb\u6d41\u611f\u76f8\u5173\u7684\u80ba\u635f\u4f24\u63d0\u4f9b\u4e86\u521b\u65b0\u7684\u601d\u8def\u3002\u8fd9\u7bc7\u6587\u7ae0\u7684\u7814\u7a76\u80cc\u666f\u548c\u5bf9\u8c61\u53ef\u8c13\u7ecf\u5178\u4e2d\u7684\u7ecf\u5178\uff0c\u5c31\u50cf\u662f\u79d1\u5b66\u7814\u7a76\u9886\u57df\u7684\u4e00\u5bf9\u9ec4\u91d1\u7ec4\u5408\uff1a\u6d41\u611f\u548c\u7ec6\u80de\u574f\u6b7b\u3002\u4f46\u662f\uff0c\u6b63\u662f\u901a\u8fc7\u5bf9\u8fd9\u4e9b\u7ecf\u5178\u8bfe\u9898\u7684\u6df1\u5165\u63a2\u7d22\uff0c\u6211\u4eec\u624d\u80fd\u53d1\u73b0\u5176\u4e2d\u8574\u542b\u7684\u65e0\u9650\u53ef\u80fd\u6027\u3002\u884c\u52a8\u8d77\u6765\uff01\u6216\u8bb8\u4e0b\u4e00\u7bc7Nature\u7684\u5c01\u9762\u6545\u4e8b\u5c31\u4f1a\u56e0\u4e3a\u4f60\u7684\u7814\u7a76\u800c\u95ea\u8000\u593a\u76ee\uff0c\u8ba9\u4e16\u754c\u4e3a\u4e4b\u60ca\u53f9\uff01<\/span>\u5982\u679c\u4f60\u4e5f\u6709\u4e00\u4e9b\u60f3\u6cd5\u5374\u4e0d\u77e5\u9053\u5982\u4f55\u5f00\u5c55\u5b9e\u9a8c\uff0c\u6216\u8005\u662f\u60f3\u8981\u91cf\u8eab\u5b9a\u5236\u5b9e\u9a8c\u65b9\u6848\uff0c\u90fd\u53ef\u4ee5\u6765\u627e\u5e08\u54e5\uff0c\u65e0\u8bba\u662f\u751f\u4fe1\u5206\u6790\u8fd8\u662f\u57fa\u7840\u5b9e\u9a8c\uff0c\u5404\u79cd\u521b\u65b0\u6027\u601d\u8def\u8bbe\u8ba1\uff0c\u5e08\u54e5\u90fd\u53ef\u4ee5\u5e2e\u4f60\u89e3\u5fe7\u54e6<\/span>~<\/span><\/span><\/strong><\/o:page><\/section>\n

\u5e08\u54e5\u4ece\u4e8b\u533b\u5b66\u76f8\u5173\u79d1\u7814\u6570\u5341\u5e74\uff0c\u7b2c\u4e00\/\u5171\u4e00\u4f5c\u8005\u53d1\u6587\u4e8c\u5341\u4f59\u7bc7\uff0c\u73b0\u5728\u4e3b\u8981\u81f4\u529b\u4e8e\u533b\u5b66\u76f8\u5173\u79d1\u7814\u53ca\u8bfe\u9898\u8bbe\u8ba1\u5de5\u4f5c<\/span>\u3002\u5e08\u54e5\u4f1a\u6301\u7eed\u4e3a\u5927\u5bb6\u5e26\u6765\u6700\u65b0\u9ad8\u5206\u6587\u7ae0\u601d\u8def\uff0c\u4ecb\u7ecd\u533b\u5b66\/\u751f\u7269\u5b66\u5404\u4e2a\u9886\u57df\u7684\u524d\u6cbf\u8fdb\u5c55\u3002\u60f3\u5b8c\u7f8e\u590d\u73b0\u6216\u8005\u5b9a\u5236\u66f4\u591a\u521b\u65b0\u6027\u601d\u8def\uff0c\u6b22\u8fce\u76f4\u63a5\u8054\u7cfb\uff01<\/span><\/p>\n

<\/mp-common-profile><\/section>\n
<\/o:page><\/section>\n
<\/mp-style-type><\/section>\n

\u539f\u6587\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff08\u4e91\u751f\u4fe1\u5b66\u751f\u7269\u4fe1\u606f\u5b66\uff09\uff1aNature|\u91cd\u78c5\u63ed\u79d8\uff01\u574f\u6b7b\u578b\u51cb\u4ea1\u4e0e\u708e\u75c7\u5173\u7cfb\u5bc6\u5207\uff0c\u5176\u6291\u5236\u5242\u5e94\u7528\u524d\u666f\u5e7f\u9614\uff01<\/a><\/p><\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u672c\u200d\u6587\u8f6c\u8f7d\u4e8e\u516c\u4f17\u53f7\u201c\u79d1\u7814\u72ee\u201d\u2014\u2014\u81f4\u529b\u4e8e\u533b\u5b66\u76f8\u5173\u79d1\u7814\u53ca\u8bfe\u9898\u8bbe\u8ba1\u5de5\u4f5c \u563f\uff0c\u5927\u5bb6\u597d\uff0c\u6211\u662f\u4f60\u4eec\u7684\u5e08\u54e5\u3002\u4f60\u4eec\u6709\u6ca1\u6709\u60f3\u8fc7\uff0c […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/43476"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=43476"}],"version-history":[{"count":2,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/43476\/revisions"}],"predecessor-version":[{"id":46857,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/43476\/revisions\/46857"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=43476"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=43476"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=43476"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}