{"id":43717,"date":"2024-06-02T01:18:36","date_gmt":"2024-06-01T17:18:36","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=43717"},"modified":"2024-06-04T18:28:07","modified_gmt":"2024-06-04T10:28:07","slug":"73aa117a99","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=43717","title":{"rendered":"\u8d85\u5f3a\u9635\u5bb9\uff01\u5de8\u566c\u7ec6\u80de\u8054\u5408\u201c\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u7ec4\u5b66\u6d4b\u5e8f\u6280\u672f\u201d\u592a\u5377\u4e86\uff010\u5b9e\u9a8c\u9ad8\u6bb5\u4f4d\u601d\u7ef4\uff0c\u8fd8\u4e0d\u5feb\u6765\u5b66\uff01"},"content":{"rendered":"
\n
<\/mp-common-profile><\/section>\n
\n
\u672c\u6587\u8f6c\u8f7d\u81ea\u516c\u4f17\u53f7\u201d\u751f\u4fe1\u9cb8\u201c\uff0c\u70b9\u51fb\u4e0a\u65b9\u540d\u7247\u52a0\u5173\u6ce8\uff0c\u6301\u7eed\u66f4\u65b0\u751f\u4fe1\u70ed\u70b9\u601d\u8def<\/p>\n<\/section>\n<\/blockquote>\n

\u6572\u9ed1\u677f\uff0c\u5404\u4f4d\u5c0f\u4f19\u4f34\u6ce8\u610f\u5566\uff01\u53c8\u5230\u4e86\u6587\u732e\u5206\u4eab\u65f6\u95f4\uff0c\u4eca\u5929\u5206\u4eab\u7684\u8fd9\u7bc7cell\u5b50\u520a\u7b80\u76f4\u592a\u725b\u4e86\uff0c\u5927\u5bb6\u53ef\u8981\u7ec6\u7ec6\u54c1\u5473\u54e6~<\/span><\/p>\n

\u5de8\u566c\u7ec6\u80de\u60f3\u5fc5\u5927\u5bb6\u90fd\u542c\u8bf4\u8fc7\u5427\uff0c\u8fd9\u53ef\u662f\u8fd1\u5e74\u6765\u56fd\u81ea\u7136\u7814\u7a76\u7684\u70ed\u70b9\uff0c<\/span>\u662f\u80bf\u7624\u5fae\u73af\u5883\u4e2d\u7684\u5173\u952e\u514d\u75ab\u7ec6\u80de\uff0c\u626e\u6f14\u7740\u91cd\u8981\u89d2\u8272<\/span><\/strong>\uff0c\u76ee\u524d\u4e5f\u6709\u5f88\u591a\u76f8\u5173\u6587\u7ae0\u53d1\u8868\u3002<\/span><\/p>\n

\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u7ec4\u5b66\uff0c\u8fd9\u4e24\u4f4d\u66f4\u662f\u91cd\u91cf\u7ea7\uff01\u4ece\u95ee\u4e16\u8d77\uff0c\u5c31\u53d7\u5230\u4e86\u79d1\u5b66\u754c\u548c\u4ea7\u4e1a\u754c\u7684\u6781\u5927\u5173\u6ce8\u3002<\/span>\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u6d4b\u5e8f\u6280\u672f<\/span>\u5c06\u7ec6\u80de\u57fa\u56e0\u8868\u8fbe\u7684\u8ba4\u8bc6<\/span>\u63a8\u8fdb\u5230\u5355\u7ec6\u80de\u7684\u5c42\u9762<\/span><\/strong>\uff1b\u800c<\/span>\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u6d4b\u5e8f\u53ef<\/span>\u4ee5\u540c\u65f6\u83b7\u5f97\u7ec6\u80de\u7684<\/span>\u7a7a\u95f4\u4f4d\u7f6e\u4fe1\u606f<\/span><\/strong>\u548c<\/span>\u57fa\u56e0\u8868\u8fbe\u6570\u636e<\/span><\/strong>\uff0c\u4e3a\u7ec4\u7ec7\u7ec6\u80de\u529f\u80fd\u3001\u5fae\u73af\u5883\u4e92\u4f5c\u3001\u53d1\u80b2\u8fc7\u7a0b\u8c31\u7cfb\u8ffd\u8e2a\u3001\u75be\u75c5\u75c5\u7406\u5b66\u7b49\u591a\u4e2a\u9886\u57df\u63d0\u4f9b\u4e86\u91cd\u8981\u7684\u7814\u7a76\u624b\u6bb5\u3002<\/span><\/p>\n

\u90a3\u4e48\uff0c<\/span>\u56fd\u81ea\u7136\u70ed\u70b9\u201c\u5de8\u566c\u7ec6\u80de\u201d\u4e0e\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u7ec4\u5b66\u6d4b\u5e8f\u6280\u672f\u7ed3\u5408\u4f1a\u8fbe\u5230\u4ec0\u4e48\u6837\u7684\u6548\u679c\u5462\uff1f<\/span><\/strong>\u4f60\u662f\u4e0d\u662f\u4e5f\u597d\u5947\u5440\uff1f\u90a3\u5c31\u548c\u963f\u9cb8\u4e00\u8d77\u6765\u770b\u770b~<\/span><\/p>\n

\u963f\u9cb8\u4eca\u5929\u5206\u4eab\u662f\u4eca\u5e742\u6708\u4efd\u7531<\/span>\u53f0\u6e7e\u9ad8\u96c4\u8363\u6c11\u603b\u533b\u9662\u5728\u300aCancer Cell International\u300b\u4e0a\u53d1\u8868\u7684\u9898\u4e3a\u201cSpatial and single-cell analyses uncover links between ALKBH1 and tumor-associated macrophages in gastric cancer\u201d\u7684\u6587\u7ae0\u3002\u6587\u7ae0\u4ee5\u56fd\u81ea\u7136\u70ed\u70b9\u201c\u5de8\u566c\u7ec6\u80de\u201d\u4e3a\u5207\u5165\u70b9\uff0c\u5229\u7528\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u5b66\u4e0e\u5355\u7ec6\u80de\u6d4b\u5e8f\u7684\u53cc\u91cdbuff\uff0c\u63ed\u793a\u4e86\u80c3\u817a\u764c\u4e2dALKBH1\u4e0e\u80bf\u7624\u76f8\u5173\u5de8\u566c\u7ec6\u80de\u4e4b\u95f4\u7684\u8054\u7cfb\uff0c\u5e76\u63a2\u8ba8\u4e86\u5176\u4f5c\u4e3a\u8bca\u65ad\u751f\u7269\u6807\u5fd7\u7269\u3001\u5f71\u54cd\u80bf\u7624\u514d\u75ab\u5fae\u73af\u5883\u4ee5\u53ca\u5728\u7cbe\u51c6\u80bf\u7624\u5b66\u4e2d\u7684\u6f5c\u5728\u4f5c\u7528\u3002<\/span>    <\/span><\/p>\n

1.<\/span>\u591a\u7ec4\u5b66<\/span><\/strong>\u65b9\u6cd5\u7684\u5e94\u7528\uff1a\u7814\u7a76\u91c7\u7528\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u5b66\u548c\u5355\u7ec6\u80deRNA\u6d4b\u5e8f\uff0c\u6765\u5168\u9762\u5206\u6790ALKBH1\u5728\u80c3\u764c\uff08STAD\uff09\u4e2d\u7684\u8868\u8fbe\u6a21\u5f0f\u53ca\u5176\u4e0e\u80bf\u7624\u514d\u75ab\u5fae\u73af\u5883\u7684\u5173\u7cfb\u3002<\/span><\/p>\n

2.ALKBH1\u4e0e<\/span>\u80bf\u7624\u514d\u75ab\u5fae\u73af\u5883<\/span><\/strong>\u7684\u5173\u8054\uff1a\u7814\u7a76\u63ed\u793a\u4e86ALKBH1\u8868\u8fbe\u6c34\u5e73\u4e0e\u80c3\u764c\u4e2d\u80bf\u7624\u76f8\u5173<\/span>\u5de8\u566c\u7ec6\u80de<\/span><\/strong>\u6d78\u6da6\u4e4b\u95f4\u7684\u6b63\u76f8\u5173\u6027\uff0c\u4e3a\u7406\u89e3ALKBH1\u5728\u80bf\u7624\u514d\u75ab\u9003\u9038\u548c\u8fdb\u5c55\u4e2d\u7684\u4f5c\u7528\u63d0\u4f9b\u4e86\u65b0\u89c6\u89d2\u3002<\/span><\/p>\n

3.<\/span>\u836f\u7269\u654f\u611f\u6027<\/span><\/strong>\u9884\u6d4b\u6a21\u578b\u7684\u5f00\u53d1\uff1a\u901a\u8fc7\u836f\u7269\u57fa\u56e0\u7ec4\u5b66\u5206\u6790\uff0c\u7814\u7a76\u5efa\u7acb\u4e86\u4e00\u4e2a\u9884\u6d4b\u6a21\u578b\uff0c\u7b5b\u9009\u51fa\u516d\u79cd\u53ef\u80fd\u589e\u5f3a\u80c3\u764c\u7ec6\u80de\u5bf9\u7279\u5b9a\u5c0f\u5206\u5b50\u836f\u7269\u654f\u611f\u6027\u7684\u5c0f\u5206\u5b50\u836f\u7269\uff0c\u4e3a\u80c3\u764c\u7684\u7cbe\u51c6\u6cbb\u7597\u63d0\u4f9b\u4e86\u6f5c\u5728\u7684\u836f\u7269\u9776\u70b9\u3002<\/span><\/p>\n

ps\uff1a\u60f3\u901a\u8fc7\u751f\u7269\u4fe1\u606f\u5b66\u6316\u6398\u5355\u7ec6\u80de\u6216\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u6570\u636e\u6765\u5b8c\u6210KPI\u7684\u670b\u53cb\uff0c\u6216\u8005\u624b\u5934\u6709\u8d44\u6e90\u4f46\u6ca1\u65f6\u95f4\u6574\u5408\u7684\u670b\u53cb\uff0c\u7edf\u7edf\u770b\u8fc7\u6765\uff0c\u963f\u9cb8\u8fd9\u8fb9\u968f\u65f6\u5f85\u547d\uff0c\u4e07\u4e8b\u4ff1\u5907\uff0c\u5c31\u5dee\u4f60\u5566\uff01<\/span><\/p>\n

\"\u8d85\u5f3a\u9635\u5bb9\uff01\u5de8\u566c\u7ec6\u80de\u8054\u5408\u201c\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u7ec4\u5b66\u6d4b\u5e8f\u6280\u672f\u201d\u592a\u5377\u4e86\uff010\u5b9e\u9a8c\u9ad8\u6bb5\u4f4d\u601d\u7ef4\uff0c\u8fd8\u4e0d\u5feb\u6765\u5b66\uff01\"<\/p>\n

\"\u8d85\u5f3a\u9635\u5bb9\uff01\u5de8\u566c\u7ec6\u80de\u8054\u5408\u201c\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u7ec4\u5b66\u6d4b\u5e8f\u6280\u672f\u201d\u592a\u5377\u4e86\uff010\u5b9e\u9a8c\u9ad8\u6bb5\u4f4d\u601d\u7ef4\uff0c\u8fd8\u4e0d\u5feb\u6765\u5b66\uff01\"<\/section>\n
\u9898\u76ee\uff1a\u7a7a\u95f4\u548c\u5355\u7ec6\u80de\u5206\u6790\u63ed\u793a\u4e86 ALKBH1 \u4e0e\u80c3\u764c\u4e2d\u80bf\u7624\u76f8\u5173\u5de8\u566c\u7ec6\u80de\u4e4b\u95f4\u7684\u8054\u7cfb<\/span><\/section>\n
\u6742\u5fd7\uff1aCancer Cell International    <\/span><\/section>\n
\u5f71\u54cd\u56e0\u5b50\uff1aIF=5.8<\/span><\/section>\n
\u53d1\u8868\u65f6\u95f4\uff1a2024\u5e742\u6708<\/span><\/section>\n
\u53cb\u60c5\u63d0\u793a\uff1a\u6587\u672b\u53ef\u83b7\u53d6\u6587\u732e\u7684DOI\u53f7\u54e6~<\/span><\/section>\n

\u6216\u8005\u70b9\u51fb\u4e0b\u65b9\u540d\u7247\u5173\u6ce8\u516c\u4f17\u53f7<\/span><\/span><\/p>\n

<\/mp-common-profile><\/section>\n
\n<\/section>\n

\u56de\u590d\u201c123\u201d\u76f4\u63a5\u540e\u53f0\u83b7\u53d6\u539f\u6587~\u6587\u732e\u7f16\u53f7\uff1a20240522<\/span><\/p>\n

\u7814\u7a76\u80cc\u666f<\/span><\/p>\n

\u80c3\u764c\u662f\u4e9a\u6d32\u548c\u5357\u7f8e\u56fd\u5bb6\u7684\u4e3b\u8981\u5065\u5eb7\u95ee\u9898\uff0c\u5176\u7279\u70b9\u662f\u9ad8\u5ea6\u7684\u80bf\u7624\u5185\u548c\u80bf\u7624\u95f4\u5f02\u8d28\u6027\uff0c\u5bfc\u81f4\u5168\u7403\u5b58\u6d3b\u7387\u8f83\u5dee\uff0c\u65e9\u671f\u8bca\u65ad\u56f0\u96be\uff0c\u9884\u540e\u4e0d\u4f73\uff0c\u56e0\u6b64\u8feb\u5207\u9700\u8981\u6539\u8fdb\u8bca\u65ad\u548c\u7cbe\u51c6\u533b\u7597\u7b56\u7565\u3002\u8868\u89c2\u9057\u4f20\u673a\u5236\u5728\u7ef4\u6301\u8868\u89c2\u57fa\u56e0\u7ec4\u6b63\u5e38\u7ed3\u6784\u4e2d\u8d77\u5173\u952e\u4f5c\u7528\uff0c\u800c<\/span>ALKBH1\u4f5c\u4e3a\u53c2\u4e0eRNA\u53bb\u7532\u57fa\u5316\u7684\u5173\u952e\u9176<\/span><\/strong>\uff0c\u5728\u591a\u79cd\u7ec6\u80de\u8fc7\u7a0b\u4e2d\u53d1\u6325\u4f5c\u7528\uff0c\u4f46\u5176\u5728\u80c3\u764c\u4e2d\u7684\u5177\u4f53\u4f5c\u7528\u5c1a\u4e0d\u6e05\u695a\u3002\u672c\u7814\u7a76\u65e8\u5728\u63a2\u7d22ALKBH1\u5728\u80c3\u764c\u4e2d\u7684\u4e34\u5e8a\u75c5\u7406\u76f8\u5173\u6027\uff0c\u5176\u5bf9\u80bf\u7624\u514d\u75ab\u5fae\u73af\u5883\u7684\u5f71\u54cd\uff0c\u4ee5\u53ca\u5176\u5728\u7cbe\u51c6\u80bf\u7624\u5b66\u4e2d\u7684\u6f5c\u529b\uff0c\u4e3a\u80c3\u764c\u6cbb\u7597\u63d0\u4f9b\u65b0\u7684\u89c6\u89d2\u548c\u7b56\u7565\u3002<\/span><\/section>\n

\u6570\u636e\u6765\u6e90<\/span><\/p>\n\n\n\n\n\n\n
\n

\u6570\u636e\u96c6\/\u961f\u5217<\/span><\/p>\n<\/td>\n

\n

\u6570\u636e\u5e93<\/span><\/p>\n<\/td>\n

\n

\u8be6\u7ec6\u4fe1\u606f<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

TCGA-STAD<\/span><\/p>\n<\/td>\n

\n

TCGA<\/span><\/p>\n<\/td>\n

\n

\u80c3\u764c\u57fa\u56e0\u8868\u8fbe\u6570\u636e<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

GSE162115\u3001GSE159929<\/span><\/p>\n<\/td>\n

\n

GEO<\/span><\/p>\n<\/td>\n

\n

\u5355\u7ec6\u80de\u6570\u636e<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u6587\u732ePMID: 35931863<\/span><\/p>\n<\/td>\n

\n

                    <\/o:p><\/span><\/p>\n<\/td>\n

\n

\u7a7a\u8f6c\u6570\u636e<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u7814\u7a76\u601d\u8def<\/span><\/p>\n

\u672c\u7814\u7a76\u9996\u5148\u5229\u7528\u591a\u7ec4\u5b66\u65b9\u6cd5\u5206\u6790\u80c3\u764c\u57fa\u56e0\u8868\u8fbe\u5dee\u5f02\u548c\u9884\u540e\u610f\u4e49\uff0c\u901a\u8fc7GEO\u548cTCGA\u6570\u636e\u5e93\u8bc6\u522b\u4e0eALKBH1\u8868\u8fbe\u76f8\u5173\u7684\u57fa\u56e0\u7a81\u53d8\u548cDNA\u62f7\u8d1d\u6570\u53d8\u5f02\u3002\u63a5\u7740\uff0c\u91c7\u7528\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u6280\u672f\u63a2\u7a76ALKBH1\u5728\u80c3\u764c\u4e0d\u540c\u533a\u57df\u7684\u8868\u8fbe\u3002\u8fdb\u4e00\u6b65\uff0c\u901a\u8fc7\u5355\u7ec6\u80deRNA\u6d4b\u5e8f\u5206\u6790ALKBH1\u8868\u8fbe\u4e0e\u514d\u75ab\u7ec6\u80de\u7fa4\u4f53\u7684\u76f8\u5173\u6027\u3002\u6700\u540e\uff0c\u5229\u7528\u836f\u7269\u57fa\u56e0\u7ec4\u5b66\u5206\u6790\u9884\u6d4b\u57fa\u4e8eALKBH1\u8868\u8fbe\u7684\u80c3\u764c\u7ec6\u80de\u836f\u7269\u654f\u611f\u6027\uff0c\u4e3a\u80c3\u764c\u7684\u7cbe\u51c6\u6cbb\u7597\u63d0\u4f9b\u6f5c\u5728\u9776\u70b9\u3002<\/span>    <\/span><\/o:page><\/section>\n

\u4e3b\u8981\u7ed3\u679c<\/span><\/p>\n

1. \u7efc\u5408\u5206\u6790\u63ed\u793aSTAD\u60a3\u8005ALKBH1\u57fa\u56e0\u7684\u9057\u4f20\u6539\u53d8<\/span><\/section>\n
\u57fa\u4e8eTCGA\u7684STAD\u6570\u636e\u96c6\uff0c\u521d\u6b65\u786e\u5b9aALKBH1\u57fa\u56e0\u7a81\u53d8\u7684\u9891\u7387\u548c\u7c7b\u578b\uff0c\u53d1\u73b0ALKBH1\u57fa\u56e0\u57282.1%\u7684\u764c\u75c7\u4e2d\u53d1\u751f\u7a81\u53d8\uff08\u56fe1A\uff09\u3002\u5728\u4e0d\u540c\u80bf\u7624\u7c7b\u578b\u4e2d\uff0cSTAD\u80bf\u7624\u7684ALKBH1\u9057\u4f20\u6539\u53d8\u9891\u7387\u6392\u540d\u7b2c\u56db\uff0c\u4e3b\u8981\u662f\u7a81\u53d8\u3001\u6269\u589e\u548c\u6df1\u5ea6\u7f3a\u5931\uff08\u56fe1B\uff09\u3002\u8fd8\u53d1\u73b0\u9519\u4e49\u7a81\u53d8\u662f\u6240\u6709TCGA\u80bf\u7624\u6837\u672c\u4e2d\u4e3b\u8981\u7684\u9057\u4f20\u6539\u53d8\u7c7b\u578b\uff08\u56fe1C\uff09\u3002cBioPortal\u5206\u6790\u663e\u793a\uff0cALKBH1\u6539\u53d8\u548c\u672a\u6539\u53d8\u7ec4\u5747\u6709\u57fa\u56e0\u6539\u53d8\u5bcc\u96c6\uff08\u56fe1D, E\uff09\uff0c\u4e14ALKBH1\u7684\u62f7\u8d1d\u6570\u53d8\u5f02\u6bd4\u6709\u663e\u8457\u53d8\u5316\uff0c\u8868\u660e\u5176\u5728STAD\u4e2d\u53ef\u80fd\u626e\u6f14\u91cd\u8981\u89d2\u8272\uff08\u56fe1F\uff09\u3002<\/span>    <\/span><\/o:page><\/section>\n
\"\u8d85\u5f3a\u9635\u5bb9\uff01\u5de8\u566c\u7ec6\u80de\u8054\u5408\u201c\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u7ec4\u5b66\u6d4b\u5e8f\u6280\u672f\u201d\u592a\u5377\u4e86\uff010\u5b9e\u9a8c\u9ad8\u6bb5\u4f4d\u601d\u7ef4\uff0c\u8fd8\u4e0d\u5feb\u6765\u5b66\uff01\"<\/span><\/section>\n
\u56fe1 ALKBH1\u5728\u80c3\u764c\u4e2d\u8868\u8fbe\u9891\u7387\u53ca\u529f\u80fd\u5bcc\u96c6\u5206\u6790<\/span><\/section>\n
\u968f\u540e\uff0c\u4eceTCGA\u6570\u636e\u5e93\u63d0\u53d6\u4e86STAD\u60a3\u8005ALKBH1\u8868\u8fbe\u6570\u636e\uff0c\u5e76\u901a\u8fc7\u7011\u5e03\u56fe\u5206\u6790\u4e86\u524d25\u4e2a\u53d7\u5f71\u54cd\u57fa\u56e0\u3002\u5206\u6790\u663e\u793aALKBH1\u8868\u8fbe\u6c34\u5e73\u4e0eSTAD\u4e2d\u5e38\u89c1\u7a81\u53d8\u57fa\u56e0\u5982TTN\u3001TP53\u76f8\u5173\u8054\uff08\u56fe2A\uff09\u3002\u8fdb\u4e00\u6b65\u7814\u7a76ALKBH1\u7a81\u53d8\u5bf9STAD\u7684\u5f71\u54cd\uff0c\u53d1\u73b0\u4e0eTTN\u7b49\u57fa\u56e0\u6709\u663e\u8457\u8054\u7cfb\uff08\u56fe2B\uff09\u3002\u901a\u8fc7Cox\u56de\u5f52\u5206\u6790\uff0c\u8bc1\u5b9e\u4e86ALKBH1\u8868\u8fbe\u4e0e\u603b\u751f\u5b58\u671f\uff08OS\uff09\u7684\u663e\u8457\u76f8\u5173\u6027\uff0c\u4e14\u98ce\u9669\u8bc4\u5206\u662f\u4e00\u4e2a\u72ec\u7acb\u7684\u9884\u540e\u56e0\u7d20\uff08\u56fe2C\uff09\u3002\u5728TCGA\u6570\u636e\u96c6\u4e2d\uff0cALKBH1\u5728\u665a\u671f\u3001\u9ad8\u5ea6\u8f6c\u79fb\u548c\u6076\u6027\u80bf\u7624\u5206\u7ea7\u4e2d\u8868\u8fbe\u4e0a\u8c03\uff0c\u8868\u660e\u5176\u5728STAD\u8fdb\u5c55\u4e2d\u7684\u91cd\u8981\u4f5c\u7528\uff08\u56fe2D-G\uff09\u3002<\/span>    <\/span><\/o:page><\/section>\n
\"\u8d85\u5f3a\u9635\u5bb9\uff01\u5de8\u566c\u7ec6\u80de\u8054\u5408\u201c\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u7ec4\u5b66\u6d4b\u5e8f\u6280\u672f\u201d\u592a\u5377\u4e86\uff010\u5b9e\u9a8c\u9ad8\u6bb5\u4f4d\u601d\u7ef4\uff0c\u8fd8\u4e0d\u5feb\u6765\u5b66\uff01\"<\/span><\/section>\n
\u56fe2 ALKBH1\u57fa\u56e0\u5728STAD\u4e2d\u7684\u8868\u8fbe\u53ca\u8868\u8fbe<\/span><\/section>\n
2. ALKBH1\u5728\u60a3\u8005\u4e2d\u7684\u786e\u5207\u4e34\u5e8a\u75c5\u7406\u610f\u4e49\u53ca\u5176\u9884\u540e\u4ef7\u503c<\/span><\/section>\n
\u901a\u8fc7Human Protein Atlas\u7684\u514d\u75ab\u7ec4\u5316\u6570\u636e\uff0c\u8bc1\u5b9e\u4e86STAD\u80bf\u7624\u7ec4\u7ec7<\/span>\u4e2dALKBH1\u86cb\u767d\u8868\u8fbe\u663e\u8457\u4e0a\u8c03<\/span><\/strong>\uff08\u56fe3A\uff09\u3002\u5229\u7528Kaplan-Meier\u548clog-rank\u68c0\u9a8c\u5206\u6790\uff0c\u53d1\u73b0\u9ad8ALKBH1\u8868\u8fbe\u4e0e\u60a3\u8005\u8f83\u77ed\u7684\u603b\u751f\u5b58\u671f\uff08OS\uff09\u3001\u8fdb\u5c55\u540e\u751f\u5b58\u671f\uff08PPS\uff09\u548c\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u76f8\u5173\uff08\u56fe3B-D\uff09\u3002ALKBH1\u5728\u80a0\u578b\u3001\u5f25\u6f2b\u6027\u548c\u6df7\u5408\u578bSTAD\u4e2d\u662f\u6f5c\u5728\u9884\u540e\u56e0\u7d20\uff0c\u800c\u5728\u57fa\u7840\u578bSTAD\u4e2d\u5219\u4e0d\u7136\uff08\u56fe3E-G\uff09\u3002\u6b64\u5916\uff0cALKBH1\u5728HER2\u9633\u6027\u548c\u9634\u6027STAD\u60a3\u8005\u4e2d\u90fd\u662f\u4e00\u4e2a<\/span>\u72ec\u7acb\u7684\u9884\u540e\u56e0\u7d20<\/span><\/strong>\uff08\u56fe3H\u548cI\uff09\u3002<\/span>    <\/span><\/o:page><\/section>\n
\"\u8d85\u5f3a\u9635\u5bb9\uff01\u5de8\u566c\u7ec6\u80de\u8054\u5408\u201c\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u7ec4\u5b66\u6d4b\u5e8f\u6280\u672f\u201d\u592a\u5377\u4e86\uff010\u5b9e\u9a8c\u9ad8\u6bb5\u4f4d\u601d\u7ef4\uff0c\u8fd8\u4e0d\u5feb\u6765\u5b66\uff01\"<\/span><\/section>\n
\u56fe3 \u4e34\u5e8a\u80c3\u764c\u7ec4\u7ec7\u4e2dALKBH1\u7684\u75c5\u7406\u53d8\u5316\u5206\u6790<\/span><\/section>\n
\u4e3a\u4e86\u5c06\u8f6c\u5f55\u7ec4\u7279\u5f81\u6620\u5c04\u5230\u7ec4\u7ec7\u5b66\u5207\u7247\u4e0a\uff08\u56fe4A\uff09\uff0c\u4f5c\u8005\u4f7f\u7528\u7a7a\u95f4\u8f6c\u5f55\u7ec4\uff08ST\uff09\u6280\u672f\u3002\u91c7\u7528\u65e0\u76d1\u7763\u805a\u7c7b\u65b9\u6cd5\u6839\u636e\u6bcf\u4e2a\u6591\u70b9\u7684\u57fa\u56e0\u8868\u8fbe\u5bf9\u6591\u70b9\u8fdb\u884c\u5206\u7ec4\uff0cSpace Ranger\u751f\u6210\u4e8610\u4e2a\u65e0\u76d1\u7763\u7c07\uff08\u56fe4B\uff09\uff0c\u8fd9\u4e9b\u7c07\u4e0e\u6bcf\u4e2a\u80bf\u7624\u5fae\u73af\u5883\u7ec6\u80de\u7684\u5df2\u77e5\u6807\u8bb0\u57fa\u56e0\u4e00\u81f4\uff0c\u8986\u76d6\u5728\u7ec4\u7ec7\u5b66\u7279\u5f81\u4e0a\u3002\u7136\u540e\u5c06STAD\u7684\u751f\u7269\u6807\u5fd7\u7269AQP1\u548cPECAM1\u4e0eALKBH1\u8fdb\u884c\u4e86\u6bd4\u8f83\uff0c<\/span>ALKBH1\u5728\u53f3\u4e0b\u89d2\u663e\u793a\u51fa\u9ad8\u6c34\u5e73<\/span>\u3002ALKBH1\u7684\u7a7a\u95f4\u8868\u8fbe\u4f4d\u7f6e\u4e0e\u8fd9\u4e24\u79cd\u751f\u7269\u6807\u5fd7\u7269\u76f8\u4f3c\u3002\u70b9\u56fe\u663e\u793a\u4e86STAD snRNA-seq\u6570\u636e\u4e2d\u4e0d\u540c\u7ec6\u80de\u7c07\uff08y\u8f74\uff09\u548c\u6807\u8bb0\u57fa\u56e0\uff08x\u8f74\uff09\u7684\u5f52\u4e00\u5316\u3001\u5bf9\u6570\u8f6c\u6362\u548c\u65b9\u5dee\u7f29\u653e\u8868\u8fbe\uff08\u56fe4C\uff09\u3002ALKBH1\u7684\u8868\u8fbe\u5728\u6240\u670910\u4e2a\u7c07\u4e2d\u59cb\u7ec8\u9ad8\u4e8e\u5176\u4ed6\u4e24\u4e2a\u80c3\u764c\u751f\u7269\u6807\u5fd7\u7269AQP1\u548cPECAM1\u3002\u6b64\u5916\uff0c\u901a\u8fc7\u57fa\u56e0\u53d8\u5f02\u5206\u6790\uff0cALKBH1\u57fa\u56e0\u53d8\u5f02\u7684\u9891\u7387\u663e\u8457\u9ad8\u4e8eAQP1\u548cPECAM1\uff08\u56fe4D\uff09\u3002<\/span>    <\/span><\/o:page><\/section>\n
\"\u8d85\u5f3a\u9635\u5bb9\uff01\u5de8\u566c\u7ec6\u80de\u8054\u5408\u201c\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u7ec4\u5b66\u6d4b\u5e8f\u6280\u672f\u201d\u592a\u5377\u4e86\uff010\u5b9e\u9a8c\u9ad8\u6bb5\u4f4d\u601d\u7ef4\uff0c\u8fd8\u4e0d\u5feb\u6765\u5b66\uff01\"<\/span><\/section>\n
\u56fe4 STAD\u4e2d\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u5b9a\u4e49\u7c07\u7684\u57fa\u56e0\u8868\u8fbe<\/span><\/section>\n
3. \u5206\u6790\u5355\u7ec6\u80deRNA\u6d4b\u5e8f\u6570\u636e\u5e93\u4ee5\u8bc4\u4f30ALKBH1\u8f6c\u5f55\u7ec4\u5b66<\/span><\/section>\n
\u4e3a\u4e86\u5728\u5355\u7ec6\u80de\u5c42\u9762\u8bc4\u4f30STAD\u4e2dALKBH1\u7684\u8f6c\u5f55\u7ec4\uff0c\u5e76\u7814\u7a76STAD\u5fae\u73af\u5883\u4e2d\u4e0d\u540c\u7ec6\u80de\u7c7b\u578b\u7684\u5f02\u8d28\u6027\uff0c\u4f7f\u7528\u5355\u7ec6\u80deRNA\u6d4b\u5e8f\u6570\u636e\u5e93\uff08GSE162115\uff09\uff0c\u53d1\u73b0ALKBH1\u4e0e\u708e\u75c7\u53cd\u5e94\u6a21\u578b\u5728\u540c\u4e00\u533a\u57df\u9ad8\u5ea6\u8868\u8fbe\uff0c\u5982\u56fe5G\u3001H\u6240\u793a\uff0c\u901a\u8fc7NF-kB\u7684TNFA\u4fe1\u53f7\u4f20\u5bfc\u548c\u5f02\u751f\u7269\u8d28\u4ee3\u8c22\u4e5f\u666e\u904d\u589e\u52a0\u3002\u56fe5F\u3001G\u8868\u660eALKBH1\u4e0e\u514d\u75ab\u7ec6\u80de\u76f8\u5173\u3002\u56e0\u6b64\uff0c\u6211\u4eec\u4f7f\u7528\u53e6\u4e00\u4e2a\u516c\u5f00\u7684\u6570\u636e\u5e93\uff08GSE159929\uff09\u8fdb\u884c\u4e86\u8fdb\u4e00\u6b65\u5206\u6790\uff0c\u70ed\u56fe\u663e\u793a\uff0c\u5728\u80c3\u7ec4\u7ec7\u4e2dALKBH1\u9ad8\u5ea6\u8868\u8fbe\uff0c\u5176\u4e2d<\/span>\u4e94\u79cd\u5de8\u566c\u7ec6\u80de\u7684\u751f\u7269\u6807\u5fd7\u7269\u4e5f\u8868\u73b0\u51fa\u9ad8\u6c34\u5e73\u8868\u8fbe<\/span><\/strong>\uff08\u56fe5J\uff09\u3002<\/span>    <\/span><\/o:page><\/section>\n
\"\u8d85\u5f3a\u9635\u5bb9\uff01\u5de8\u566c\u7ec6\u80de\u8054\u5408\u201c\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u7ec4\u5b66\u6d4b\u5e8f\u6280\u672f\u201d\u592a\u5377\u4e86\uff010\u5b9e\u9a8c\u9ad8\u6bb5\u4f4d\u601d\u7ef4\uff0c\u8fd8\u4e0d\u5feb\u6765\u5b66\uff01\"<\/span><\/section>\n
\u56fe5 \u5355\u7ec6\u80deRNA\u6d4b\u5e8f\u5206\u6790\u80fd\u591f\u8bc6\u522b\u514d\u75ab\u7ec6\u80de\u7fa4<\/span><\/section>\n
4 . \u5de8\u566c\u7ec6\u80de\u6d78\u6da6\u4e0eALKBH1\u8fc7\u8868\u8fbe\u7684\u5173\u7cfb<\/span><\/section>\n
\u4ece\u56fe5A-H\u6240\u793a\u7684\u5355\u7ec6\u80de\u6d4b\u5e8f\u6570\u636e\u5e93\u4e2d\u786e\u5b9a\u4e86\u4e0e\u5de8\u566c\u7ec6\u80de\u9ad8\u5ea6\u76f8\u5173\u7684\u96c6\u7fa4\u3002\u7531\u4e8e\u5de8\u566c\u7ec6\u80de\u5177\u6709\u7ec4\u7ec7\u9a7b\u7559\u7279\u6027\u5e76\u5177\u6709\u4fc3\u708e\u6216\u6297\u708e\u529f\u80fd\uff0c\u4f5c\u8005\u8fdb\u4e00\u6b65\u5206\u6790\u4e86ALKBH1\u4e0e\u80bf\u7624\u514d\u75ab\u76f8\u4e92\u4f5c\u7528\u4e4b\u95f4\u7684\u5173\u7cfb\uff08\u56fe6A\uff09\u3002Spearman\u76f8\u5173\u5206\u6790\u663e\u793aALKBH1\u7684\u8868\u8fbe\u4e0eSTAD\u4e2d\u5927\u591a\u6570<\/span>\u80bf\u7624\u6d78\u6da6\u6027\u5de8\u566c\u7ec6\u80de\u5448\u6b63\u76f8\u5173<\/span><\/strong>\uff08\u56fe6B\uff09\u3002scTIME\u95e8\u6237\u68c0\u7d22\u5230\u5404\u79cd<\/span>T\u7ec6\u80de\u4e9a\u7fa4\u548c\u5de8\u566c\u7ec6\u80de<\/span><\/strong>\u4e4b\u95f4\u7684\u590d\u6742\u76f8\u4e92\u4f5c\u7528\uff0c\u8fd9\u662f\u5728STAD\u4e2d\u68c0\u6d4b\u5230\u7684\u6700\u5f3a\u7684\u7ec6\u80de\u95f4\u901a\u8baf\uff08\u56fe6C\uff09\u3002<\/span>    <\/span><\/o:page><\/section>\n
\"\u8d85\u5f3a\u9635\u5bb9\uff01\u5de8\u566c\u7ec6\u80de\u8054\u5408\u201c\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u7ec4\u5b66\u6d4b\u5e8f\u6280\u672f\u201d\u592a\u5377\u4e86\uff010\u5b9e\u9a8c\u9ad8\u6bb5\u4f4d\u601d\u7ef4\uff0c\u8fd8\u4e0d\u5feb\u6765\u5b66\uff01\"<\/span><\/section>\n
\u56fe6 ALKBH1\u5bf9\u80bf\u7624\u514d\u75ab\u5fae\u73af\u5883\uff08TIME\uff09\u5f71\u54cd\u7684\u7814\u7a76<\/span><\/section>\n
\u4f5c\u8005\u8bc4\u4f30\u4e86ALKBH1\u4e0e<\/span>\u5de8\u566c\u7ec6\u80deM0\u3001M1\u548cM2\u4e9a\u578b<\/span><\/strong>\u4e4b\u95f4\u7684\u76f8\u5173\u6027\uff0c\u53d1\u73b0\u4e24\u8005\u5448<\/span>\u6b63\u76f8\u5173<\/span><\/strong>\uff08\u56fe7A\uff09\u3002\u5e76\u4e14ALKBH1\u4e0e<\/span>\u5de8\u566c\u7ec6\u80de\u751f\u7269\u6807\u5fd7\u7269<\/span><\/strong>\uff08CD163\u3001CD68\u3001MARCO\u3001MRC1\u548cMSR1\uff09\u5448<\/span>\u6b63\u76f8\u5173<\/span><\/strong>\uff08\u56fe7B\uff09\u3002<\/span>    <\/span><\/o:page><\/section>\n
\"\u8d85\u5f3a\u9635\u5bb9\uff01\u5de8\u566c\u7ec6\u80de\u8054\u5408\u201c\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u7ec4\u5b66\u6d4b\u5e8f\u6280\u672f\u201d\u592a\u5377\u4e86\uff010\u5b9e\u9a8c\u9ad8\u6bb5\u4f4d\u601d\u7ef4\uff0c\u8fd8\u4e0d\u5feb\u6765\u5b66\uff01\"<\/span><\/section>\n
\u56fe7 \u63a2\u8ba8ALKBH1\u4e0eSTAD\u514d\u75ab\u6d78\u6da6\u7684\u5173\u7cfb<\/span><\/section>\n
5 . \u901a\u8fc7\u836f\u7269\u9057\u4f20\u7b5b\u9009\u9274\u5b9a\u6f5c\u5728\u7684STAD ALKBH1\u6291\u5236\u5242<\/span><\/section>\n
\u672c\u7814\u7a76\u65e8\u5728\u901a\u8fc7GDSC\u6570\u636e\u5e93\u7b5b\u9009\u5728ALKBH1\u9ad8\u8868\u8fbe\u60c5\u51b5\u4e0b\u66f4\u6709\u6548\u7684\u836f\u7269\uff0c\u4ee5\u786e\u5b9a\u5bf9STAD\u7684\u6f5c\u5728\u6cbb\u7597\u836f\u7269\u3002\u901a\u8fc7CRISPR-Cas9\u6280\u672f\u5728STAD\u7ec6\u80de\u4e2d\u6572\u9664ALKBH1\uff0c\u5e76\u5206\u6790430\u79cd\u836f\u7269\u5bf9\u5176\u7684\u5f71\u54cd\uff08\u56fe8A\uff09\u3002\u7814\u7a76\u53d1\u73b06\u79cd\u836f\u7269\u2014<\/span>Elesclomol\u3001Vinorelbine\u3001Alisertib\u3001ZM447439\u3001RU-SKI 43\u548cFTY-720\uff0c<\/span><\/strong>\u5728ALKBH1\u6572\u9664\u7684STAD\u7ec6\u80de\u4e2d\u8868\u73b0\u51fa\u6539\u53d8\u7684\u6548\u529b\uff08\u56fe8B-G\uff09\u3002\u7279\u522b\u662f<\/span>\uff0csgALKBH1<\/span>\u6548\u7387\u9ad8\u7684STAD\u7ec6\u80de\u7cfb\u5bf9\u8fd9\u4e9b\u836f\u7269\u66f4\u654f\u611f\uff0c\u8868\u660e\u8fd9\u4e9b\u836f\u7269\u53ef\u80fd\u4f5c\u4e3a\u9776\u5411ALKBH1\u7684\u6297\u764c\u836f\u7269\u3002<\/span>    <\/span><\/o:page><\/section>\n
\"\u8d85\u5f3a\u9635\u5bb9\uff01\u5de8\u566c\u7ec6\u80de\u8054\u5408\u201c\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u7ec4\u5b66\u6d4b\u5e8f\u6280\u672f\u201d\u592a\u5377\u4e86\uff010\u5b9e\u9a8c\u9ad8\u6bb5\u4f4d\u601d\u7ef4\uff0c\u8fd8\u4e0d\u5feb\u6765\u5b66\uff01\"<\/span><\/section>\n
\u56fe8 \u80c3\u764c\u7ec6\u80de\u7684\u836f\u7269\u654f\u611f\u6027\u548c\u7ec6\u80de\u6bd2\u6027\u5206\u6790<\/span><\/section>\n
\u6587\u7ae0\u5c0f\u7ed3<\/span><\/section>\n
\u672c\u7814\u7a76\u57fa\u4e8e\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u5b66\u7684\u65b9\u6cd5\uff0c\u63ed\u793a<\/span>\u80c3\u817a\u764c\u4e2dALKBH1\u4e0e\u80bf\u7624\u76f8\u5173\u5de8\u566c\u7ec6\u80de\u4e4b\u95f4\u7684\u8054\u7cfb\uff0c\u5e76\u63a2\u8ba8\u4e86\u5176\u4f5c\u4e3a\u8bca\u65ad\u751f\u7269\u6807\u5fd7\u7269\u3001\u5f71\u54cd\u80bf\u7624\u514d\u75ab\u5fae\u73af\u5883\u4ee5\u53ca\u5728\u7cbe\u51c6\u80bf\u7624\u5b66\u4e2d\u7684\u6f5c\u5728\u4f5c\u7528\uff0c\u4e3a\u8bca\u65ad\u548c\u9884\u540e\u5e94\u7528\u63d0\u4f9b\u4e86\u65b0\u7684\u89c6\u89d2\u3002<\/span><\/span>\u8fd9\u4e48\u8d5e\u7684\u6587\u7ae0\uff0c\u8fd8\u4e0d\u70b9\u4e2a\u6536\u85cf+\u5728\u770b\uff0c\u7ec6\u7ec6\u54c1\u5473\uff1f\u53e6\u5916\u963f\u9cb8\u4e5f\u53ef\u4ee5\u50cf\u8be5\u7814\u7a76\u4e00\u6837\uff0c\u63d0\u4f9b\u5168\u65b9\u4f4d\u7684\u5355\u7ec6\u80de+\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u5206\u6790\uff0c\u4e3a\u4f60\u7684\u9ad8\u5206SCI\u4e4b\u8def\u4fdd\u9a7e\u62a4\u822a\uff01\u9762\u9762\u4ff1\u5230\uff0c\u53ea\u7b49\u4f60\u6765\uff0c\u611f\u5174\u8da3\u7684\u6293\u7d27\u626b\u63cf\u4e0b\u65b9\u4e8c\u7ef4\u7801\u8054\u7cfb\u6211\u5427~<\/span><\/section>\n

\u539f\u6587\u4fe1\u606f\uff1adoi: 10.1186\/s12935-024-03232-5.  <\/span><\/p>\n

PMID: 38317214<\/span><\/section>\n
\n
\n
\n
\n
\n
\n
\"\u8d85\u5f3a\u9635\u5bb9\uff01\u5de8\u566c\u7ec6\u80de\u8054\u5408\u201c\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u7ec4\u5b66\u6d4b\u5e8f\u6280\u672f\u201d\u592a\u5377\u4e86\uff010\u5b9e\u9a8c\u9ad8\u6bb5\u4f4d\u601d\u7ef4\uff0c\u8fd8\u4e0d\u5feb\u6765\u5b66\uff01\"<\/section>\n<\/section>\n<\/section>\n
\n
\n

\u5b9a\u5236\u751f\u4fe1\u5206\u6790<\/strong><\/span><\/p>\n

\u4e91\u670d\u52a1\u5668\u79df\u8d41<\/strong><\/span><\/p>\n

\u626b\u7801\u54a8\u8be2\u963f\u9cb8<\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n
\n
<\/mp-common-profile><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
<\/mp-style-type><\/section>\n<\/section>\n

\u539f\u6587\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff08\u4e91\u751f\u4fe1\u5b66\u751f\u7269\u4fe1\u606f\u5b66\uff09\uff1a\u8d85\u5f3a\u9635\u5bb9\uff01\u5de8\u566c\u7ec6\u80de\u8054\u5408\u201c\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u7ec4\u5b66\u6d4b\u5e8f\u6280\u672f\u201d\u592a\u5377\u4e86\uff010\u5b9e\u9a8c\u9ad8\u6bb5\u4f4d\u601d\u7ef4\uff0c\u8fd8\u4e0d\u5feb\u6765\u5b66\uff01<\/a><\/p><\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u672c\u6587\u8f6c\u8f7d\u81ea\u516c\u4f17\u53f7\u201d\u751f\u4fe1\u9cb8\u201c\uff0c\u70b9\u51fb\u4e0a\u65b9\u540d\u7247\u52a0\u5173\u6ce8\uff0c\u6301\u7eed\u66f4\u65b0\u751f\u4fe1\u70ed\u70b9\u601d\u8def \u6572\u9ed1\u677f\uff0c\u5404\u4f4d\u5c0f\u4f19\u4f34\u6ce8\u610f\u5566\uff01\u53c8\u5230\u4e86\u6587\u732e\u5206\u4eab […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/43717"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=43717"}],"version-history":[{"count":2,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/43717\/revisions"}],"predecessor-version":[{"id":46196,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/43717\/revisions\/46196"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=43717"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=43717"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=43717"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}