{"id":48640,"date":"2024-06-15T20:08:15","date_gmt":"2024-06-15T12:08:15","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=48640"},"modified":"2024-06-15T20:08:15","modified_gmt":"2024-06-15T12:08:15","slug":"%e6%9c%89%e6%88%91%e5%9c%a8%ef%bc%8c%e5%88%ab%e5%ae%b3%e6%80%95%ef%bc%81%e5%88%a9%e7%94%a8dnaman%e8%bf%9b%e8%a1%8c%e6%a0%b8%e9%85%b8%e6%af%94%e5%af%b9%e7%9a%84%e6%95%99%e7%a8%8b%e6%9d%a5%e5%95%a6-2","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=48640","title":{"rendered":"\u6709\u6211\u5728\uff0c\u522b\u5bb3\u6015\uff01\u5229\u7528DNAMAN\u8fdb\u884c\u6838\u9178\u6bd4\u5bf9\u7684\u6559\u7a0b\u6765\u5566~"},"content":{"rendered":"


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data={\"mp\":\"\u751f\u4fe1\u679c\",\"title\":\"\u6709\u6211\u5728\uff0c\u522b\u5bb3\u6015\uff01\u5229\u7528DNAMAN\u8fdb\u884c\u6838\u9178\u6bd4\u5bf9\u7684\u6559\u7a0b\u6765\u5566~\",\"time\":\"2023-04-15 19:00:11\",\"timeStamp\":\"1681556411\"};\n<\/script><br \/>\n<body><\/p>\n<div class=\"rich_media\">\n<h1 class=\"rich_media_title\" id=\"activity-name\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247486732&idx=1&sn=609bfad819a6e35dd1744284c01ea5ff&chksm=cf7c9dc9f80b14dfe4d838e0bceb844c92c630cbe348b04377d4148c237a1cad895f4cbc6b55#rd\" target=\"_blank\" rel=\"noopener\">\u6709\u6211\u5728\uff0c\u522b\u5bb3\u6015\uff01\u5229\u7528DNAMAN\u8fdb\u884c\u6838\u9178\u6bd4\u5bf9\u7684\u6559\u7a0b\u6765\u5566~<\/a><\/h1>\n<div id=\"meta_content\" class=\"rich_media_meta_list\"><span id=\"copyright_logo\" class=\"wx_tap_link js_wx_tap_highlight rich_media_meta icon_appmsg_tag appmsg_title_tag weui-wa-hotarea\">\u539f\u521b  <\/span><span class=\"rich_media_meta rich_media_meta_text\">\u5c0f\u679c  <\/span><span class=\"rich_media_meta rich_media_meta_nickname\" id=\"profileBt\"><a href=\"javascript:void(0);\" class=\"wx_tap_link js_wx_tap_highlight weui-wa-hotarea\" id=\"js_name\">\u751f\u4fe1\u679c  <\/a><\/span><em id=\"publish_time\" class=\"rich_media_meta rich_media_meta_text\">2023-04-15 19:00:11<\/em><\/div>\n<p><content><\/p>\n<p data-mpa-powered-by=\"yiban.io\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.18518518518518517\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_0CuCiczxXATRA1NT7QsFibQGILBxvQ-60.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/mmbiz_jpg\/zcicibWZessAx2cF5xxW6pBGPmgTUt8qTlL9RiabvDGL72zZRhzS10IN01ZYt0CuCiczxXATRA1NT7QsFibQGILBxvQ\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"1080\" style=\"white-space: normal;font-size: 16px;text-align: center;\" data-recalc-dims=\"1\"><\/p>\n<p style=\"margin-bottom: 10px;font-size: 16px;white-space: normal;box-sizing: border-box;\">DNAman\u662f\u4e00\u6b3e\u4e13\u4e1a\u7684\u5206\u5b50\u751f\u7269\u5b66\u8f6f\u4ef6\uff0c\u53ef\u4ee5\u7528\u4e8eDNA\u5e8f\u5217\u5206\u6790\u3001\u6bd4\u5bf9\u3001\u4fee\u526a\u3001\u91cd\u7ec4\u3001\u514b\u9686\u7b49\u64cd\u4f5c\u3002<\/p>\n<p style=\"margin-bottom: 10px;font-size: 16px;white-space: normal;box-sizing: border-box;\">\u9996\u5148\u5bfc\u5165\u6bd4\u5bf9\u5e8f\u5217\uff0c\u5c0f\u679c\u8fd8\u662f\u7528\u4e0a\u6b21\u505a\u8fdb\u5316\u6811\u7528\u5230\u7684\u5e8f\u5217\uff1a\u901a\u8fc7NCBIhttps:\/\/www.ncbi.nlm.nih.gov\/\u83b7\u53d6\u5c3c\u7f57\u7f57\u975e\u9c7c(Oreochromis niloticus)\u3001\u6591\u70b9\u96c0\u9cdd(Lepisosteus oculatus)\u3001\u9752\u9cc9(Oryzias latipes)\u3001\u7ea2\u9ccd\u4e1c\u65b9\u9c80(Takifugu rubripes)\u3001\u6591\u9a6c\u9c7c(Danio rerio)\u3001\u5c0f\u9f20(Mus musculus)\u548c\u4eba(Homo sapiens)\u7684SOCS1\u57fa\u56e0fasta\u5e8f\u5217\u3002<\/p>\n<p style=\"margin-bottom: 10px;font-size: 16px;white-space: normal;box-sizing: border-box;\">\u6253\u5f00DNAman9\u8f6f\u4ef6\uff0c\u9009\u62e9\u201cSequence\u201d\u83dc\u5355\u4e0b\u7684\u201cAlign sequences\u201d\u9009\u9879\u3002<\/p>\n<p style=\"margin-bottom: 10px;font-size: 16px;white-space: normal;box-sizing: border-box;\">\u5728\u201cAlign sequences\u201d\u7a97\u53e3\u4e2d\uff0c\u70b9\u51fb\u201cMutiple Sequence Alignment\u201d\u6309\u94ae<\/p>\n<p style=\"margin-bottom: 0px;font-size: 16px;white-space: normal;text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5848484848484848\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_sLVxpVqIKHQbgCGPgohkT6X2vbGayw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/mmbiz_png\/zcicibWZessAwtJh5WPmw9Q70nJCdPAypjicicNc2ShJHf0dOxjuibqtrlkTicsLVxpVqIKHQbgCGPgohkT6X2vbGayw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"330\" data-recalc-dims=\"1\"><\/p>\n<p style=\"margin-bottom: 10px;font-size: 16px;white-space: normal;box-sizing: border-box;\"> <\/p>\n<p style=\"margin-bottom: 0px;font-size: 16px;white-space: normal;text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.8284518828451883\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_Rh60ZuEicvnagxFibK5dwabchctH8Q.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/mmbiz_png\/zcicibWZessAwtJh5WPmw9Q70nJCdPAypjmZzU4R6ejA6aPEM1iajytw69vvFRh60ZuEicvnagxFibK5dwabchctH8Q\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"239\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"margin-bottom: 10px;font-size: 16px;white-space: normal;box-sizing: border-box;\">\u6ce8\u610f\u6700\u4e0b\u65b9\u5bfc\u5165\u7684\u5e8f\u5217\u662fDNA\u5e8f\u5217\u8fd8\u662f\u86cb\u767d\u5e8f\u5217\uff0c\u52fe\u9009\u76f8\u5e94\u7684\u5373\u53ef\uff0c\u70b9\u51fb\u53f3\u4fa7File\u5bfc\u5165fasta\u5e8f\u5217\uff0c\u4e0b\u4e00\u6b65<\/p>\n<p style=\"margin-bottom: 0px;font-size: 16px;white-space: normal;text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.8547717842323651\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_7f289KichGMJcdQJIeJaAq1ibibOjg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/mmbiz_png\/zcicibWZessAwtJh5WPmw9Q70nJCdPAypjTaalibtibAdYhlwHVj1q7fLfwhQrz7f289KichGMJcdQJIeJaAq1ibibOjg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"241\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"margin-bottom: 10px;font-size: 16px;white-space: normal;box-sizing: border-box;\">\u7ee7\u7eed\u4e0b\u4e00\u9875\uff0c\u5728\u8fd9\u4e2a\u754c\u9762\u4e00\u822c\u9ed8\u8ba4\u5373\u53ef<\/p>\n<p style=\"margin-bottom: 0px;font-size: 16px;white-space: normal;text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.8843283582089553\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_V396HFGhLsbcxovKAHQnDA6zuELFzg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/mmbiz_png\/zcicibWZessAwtJh5WPmw9Q70nJCdPAypj6asPJBacXtJL0DLwwzqia3VSfV396HFGhLsbcxovKAHQnDA6zuELFzg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"268\" data-recalc-dims=\"1\"><\/p>\n<p style=\"margin-bottom: 10px;font-size: 16px;white-space: normal;box-sizing: border-box;\"> <\/p>\n<p style=\"margin-bottom: 0px;font-size: 16px;white-space: normal;text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.8522727272727273\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_YGQH1l458zt6tJePyhvia1EQW8ndVA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/mmbiz_png\/zcicibWZessAwtJh5WPmw9Q70nJCdPAypjc80XaMQynev4fYo1LvHM7U02gYGQH1l458zt6tJePyhvia1EQW8ndVA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"264\" data-recalc-dims=\"1\"><\/p>\n<p style=\"margin-bottom: 10px;font-size: 16px;white-space: normal;box-sizing: border-box;\">   * K-tuple\u7684\u5927\u5c0f\u4e00\u822c\u8bbe\u7f6e\u57282-6\u4e4b\u95f4\uff0c\u5177\u4f53\u53d6\u51b3\u4e8e\u5e8f\u5217\u7684\u957f\u5ea6\u548c\u53d8\u5f02\u6027\u3002\u901a\u5e38\u60c5\u51b5\u4e0b\uff0c\u8f83\u77ed\u7684K-tuple\u80fd\u591f\u66f4\u597d\u5730\u6355\u6349\u5e8f\u5217\u4e2d\u7684\u5c40\u90e8\u76f8\u4f3c\u6027\uff0c\u4f46\u53ef\u80fd\u4f1a\u5728\u6bd4\u5bf9\u8fc7\u7a0b\u4e2d\u4ea7\u751f\u8bef\u914d\u3002\u800c\u8f83\u957f\u7684K-tuple\u5219\u80fd\u591f\u66f4\u597d\u5730\u533a\u5206\u5e8f\u5217\u7684\u5dee\u5f02\uff0c\u4f46\u53ef\u80fd\u4f1a\u9519\u8fc7\u4e00\u4e9b\u76f8\u4f3c\u6027\u533a\u57df\u3002<\/p>\n<p style=\"margin-bottom: 10px;font-size: 16px;white-space: normal;box-sizing: border-box;\">     *Gap penalty\u548cgap extension penalty\uff1a\u8fd9\u4e24\u4e2a\u53c2\u6570\u63a7\u5236\u7a7a\u4f4d\u7684\u7f5a\u5206\uff0c\u5373\u7a7a\u4f4d\u51fa\u73b0\u7684\u60e9\u7f5a\u7a0b\u5ea6\u3002\u4e00\u822c\u60c5\u51b5\u4e0b\uff0cgap penalty\u7684\u503c\u5e94\u8be5\u6bd4gap extension penalty\u9ad8\uff0c\u56e0\u4e3a\u5728\u5b9e\u9645\u751f\u7269\u5e8f\u5217\u4e2d\uff0c\u7a7a\u4f4d\u51fa\u73b0\u7684\u6982\u7387\u8f83\u4f4e\u3002\u5efa\u8bae\u521d\u59cb\u503c\u5206\u522b\u8bbe\u7f6e\u4e3a10\u548c0\u3002<\/p>\n<p style=\"margin-bottom: 10px;font-size: 16px;white-space: normal;box-sizing: border-box;\">   * delay divergent seqs%”\u662f\u591a\u5e8f\u5217\u6bd4\u5bf9\u4e2d\u7684\u4e00\u4e2a\u53c2\u6570\uff0c\u5176\u4f5c\u7528\u662f\u63a7\u5236\u5728\u6bd4\u5bf9\u8fc7\u7a0b\u4e2d\u8df3\u8fc7\u9ad8\u5ea6\u5206\u6b67\u7684\u5e8f\u5217\uff0c\u4ee5\u51cf\u5c11\u8fd9\u4e9b\u5e8f\u5217\u5bf9\u6bd4\u5bf9\u7ed3\u679c\u7684\u5f71\u54cd\u3002<\/p>\n<p style=\"margin-bottom: 10px;font-size: 16px;white-space: normal;box-sizing: border-box;\">\u5b8c\u6210\u4ee5\u540e\u7b49\u5f85\u7ed3\u679c\uff0c\u5728\u8fd9\u4e2a\u7a97\u53e3\u4e2d\uff0c\u53ef\u4ee5\u67e5\u770b\u5e8f\u5217\u7684\u6bd4\u5bf9\u7ed3\u679c\uff0c\u5305\u62ec\u6bd4\u5bf9\u5f97\u5206\u3001\u76f8\u4f3c\u6027\u77e9\u9635\u3001\u5e8f\u5217\u7684\u540c\u6e90\u6027\u7b49\u4fe1\u606f\u3002<\/p>\n<p style=\"margin-bottom: 10px;font-size: 16px;white-space: normal;box-sizing: border-box;\">\u53ef\u4ee5\u4f7f\u7528\u201cFile\u201d\u83dc\u5355\u4e0b\u7684\u201cSave as\u201d\u9009\u9879\u5c06\u6bd4\u5bf9\u7ed3\u679c\u4fdd\u5b58\u4e3a\u6587\u672c\u6587\u4ef6\uff0c\u4e5f\u53ef\u4ee5\u9009\u4e2d\u7ed3\u679c\u540e\u4f7f\u7528\u201cEdit\u201d\u83dc\u5355\u4e0b\u7684\u201cCopy\u201d\u9009\u9879\u5c06\u6bd4\u5bf9\u7ed3\u679c\u590d\u5236\u5230\u526a\u8d34\u677f\u4e2d\uff0c\u4ee5\u4fbf\u4e8e\u5728\u5176\u4ed6\u8f6f\u4ef6\u4e2d\u8fdb\u884c\u5206\u6790\u548c\u5904\u7406\u3002<\/p>\n<p style=\"margin-bottom: 0px;font-size: 16px;white-space: normal;text-align: center;\"><img 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normal;box-sizing: border-box;\"> <\/p>\n<p style=\"margin-bottom: 10px;font-size: 16px;white-space: normal;box-sizing: border-box;\">\u5982\u679c\u4f60\u8fd8\u5728\u4e3a\u751f\u4fe1\u5206\u6790\u82e6\u607c\uff0c\u82e6\u82e6\u5b66\u4e60\u5374\u4e0d\u5f97\u8981\u9886\uff0c\u4e00\u5b9a\u8981\u8bd5\u4e00\u4e0b\u8fd9\u4e2a\u7ebf\u4e0a\u5e73\u53f0\uff0c\u4ec0\u4e48circos\u56fe\u3001\u5c0f\u63d0\u7434\u56fe\u3001\u66fc\u54c8\u987f\u56fe\u53ea\u8981\u4e0a\u4f20\u6570\u636e\u7edf\u7edf\u4e0d\u5728\u8bdd\u4e0b\uff01<\/p>\n<p style=\"margin-bottom: 0px;font-size: 16px;white-space: normal;text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5116959064327485\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_yicrVianBBZboWOyyGZV4o0iacYYjg.png?w=640\" 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center;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\"><span style=\"font-size: 15px;box-sizing: border-box;\">\u751f\u4fe1\u4ebaR\u8bed\u8a00\u5b66\u4e60\u5fc5\u5907<\/span><\/strong><\/p>\n<p style=\"box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\"><span style=\"font-size: 15px;box-sizing: border-box;\">\u7acb\u523b\u62e5\u6709\u4e00\u4e2aRstudio\u8d26\u53f7<\/span><\/strong><\/p>\n<p style=\"box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\"><span style=\"font-size: 15px;box-sizing: border-box;\">\u5f00\u542f\u5347\u7ea7\u6a21\u5f0f\u5427<\/span><\/strong><\/p>\n<p style=\"box-sizing: border-box;\"><span style=\"color: rgb(255, 129, 36);box-sizing: border-box;font-size: 12px;\">\uff0856\u7ebf\u7a0b\uff0c256G\u5185\u5b58\uff0c\u4e2a\u4eba\u5b58\u50a81T\uff09<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;width: 162.257px;vertical-align: top;align-self: flex-start;flex: 0 0 auto;height: auto;box-sizing: border-box;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;text-align: center;line-height: 0;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;box-sizing: border-box;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-cropselx1=\"0\" data-cropselx2=\"162\" data-cropsely1=\"0\" data-cropsely2=\"162\" data-ratio=\"1\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_ib2l1ye6HNIkwTG696C2pf9yAtdeGA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/mmbiz_png\/zcicibWZessAyB69UyXDLG0wQcISNwmL6DlpIKVBnCSOXHTWJhLcxic2qtibaib2l1ye6HNIkwTG696C2pf9yAtdeGA\/640?wx_fmt=png'\" data-type=\"jpeg\" data-w=\"400\" style=\"height: 111px;vertical-align: middle;width: 111px;box-sizing: border-box;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"white-space: normal;box-sizing: border-box;\">\n<p style=\"text-align: center;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwNjE0MDY3MQ==&mid=2650750896&idx=2&sn=eedf639d72ed894b623b97cb453ec731&chksm=831a7820b46df136d60bbcd98da1545dc7cdc7d23013ee352ad58b8413bd8b74496a1cb24158&scene=21#wechat_redirect\" textvalue=\"\u4f60\u5df2\u9009\u4e2d\u4e86\u6dfb\u52a0\u94fe\u63a5\u7684\u5185\u5bb9\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"1\" rel=\"noopener\"><span class=\"js_jump_icon h5_image_link\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.3333333333333333\" data-s=\"300,640\" 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