{"id":48917,"date":"2024-06-15T20:08:25","date_gmt":"2024-06-15T12:08:25","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=48917"},"modified":"2024-06-15T23:34:08","modified_gmt":"2024-06-15T15:34:08","slug":"%e6%9c%89%e6%88%91%e5%9c%a8%ef%bc%8c%e5%88%ab%e5%ae%b3%e6%80%95%ef%bc%81%e5%88%a9%e7%94%a8dnaman%e8%bf%9b%e8%a1%8c%e6%a0%b8%e9%85%b8%e6%af%94%e5%af%b9%e7%9a%84%e6%95%99%e7%a8%8b%e6%9d%a5%e5%95%a6-4","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=48917","title":{"rendered":"\u6709\u6211\u5728\uff0c\u522b\u5bb3\u6015\uff01\u5229\u7528DNAMAN\u8fdb\u884c\u6838\u9178\u6bd4\u5bf9\u7684\u6559\u7a0b\u6765\u5566~"},"content":{"rendered":"
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\u6709\u6211\u5728\uff0c\u522b\u5bb3\u6015\uff01\u5229\u7528DNAMAN\u8fdb\u884c\u6838\u9178\u6bd4\u5bf9\u7684\u6559\u7a0b\u6765\u5566~<\/a><\/h1>\n
\u539f\u521b\u00a0\u00a0<\/span>\u5c0f\u679c\u00a0\u00a0<\/span><\/a>\u751f\u4fe1\u679c\u00a0\u00a0<\/span>2023-04-15 19:00:11<\/em><\/div>\n

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DNAman\u662f\u4e00\u6b3e\u4e13\u4e1a\u7684\u5206\u5b50\u751f\u7269\u5b66\u8f6f\u4ef6\uff0c\u53ef\u4ee5\u7528\u4e8eDNA\u5e8f\u5217\u5206\u6790\u3001\u6bd4\u5bf9\u3001\u4fee\u526a\u3001\u91cd\u7ec4\u3001\u514b\u9686\u7b49\u64cd\u4f5c\u3002<\/p>\n

\u9996\u5148\u5bfc\u5165\u6bd4\u5bf9\u5e8f\u5217\uff0c\u5c0f\u679c\u8fd8\u662f\u7528\u4e0a\u6b21\u505a\u8fdb\u5316\u6811\u7528\u5230\u7684\u5e8f\u5217\uff1a\u901a\u8fc7NCBIhttps:\/\/www.ncbi.nlm.nih.gov\/\u83b7\u53d6\u5c3c\u7f57\u7f57\u975e\u9c7c(Oreochromis niloticus)\u3001\u6591\u70b9\u96c0\u9cdd(Lepisosteus oculatus)\u3001\u9752\u9cc9(Oryzias latipes)\u3001\u7ea2\u9ccd\u4e1c\u65b9\u9c80(Takifugu rubripes)\u3001\u6591\u9a6c\u9c7c(Danio rerio)\u3001\u5c0f\u9f20(Mus musculus)\u548c\u4eba(Homo sapiens)\u7684SOCS1\u57fa\u56e0fasta\u5e8f\u5217\u3002<\/p>\n

\u6253\u5f00DNAman9\u8f6f\u4ef6\uff0c\u9009\u62e9\u201cSequence\u201d\u83dc\u5355\u4e0b\u7684\u201cAlign sequences\u201d\u9009\u9879\u3002<\/p>\n

\u5728\u201cAlign sequences\u201d\u7a97\u53e3\u4e2d\uff0c\u70b9\u51fb\u201cMutiple\u00a0Sequence\u00a0Alignment\u201d\u6309\u94ae<\/p>\n

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\u6ce8\u610f\u6700\u4e0b\u65b9\u5bfc\u5165\u7684\u5e8f\u5217\u662fDNA\u5e8f\u5217\u8fd8\u662f\u86cb\u767d\u5e8f\u5217\uff0c\u52fe\u9009\u76f8\u5e94\u7684\u5373\u53ef\uff0c\u70b9\u51fb\u53f3\u4fa7File\u5bfc\u5165fasta\u5e8f\u5217\uff0c\u4e0b\u4e00\u6b65<\/p>\n

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\u7ee7\u7eed\u4e0b\u4e00\u9875\uff0c\u5728\u8fd9\u4e2a\u754c\u9762\u4e00\u822c\u9ed8\u8ba4\u5373\u53ef<\/p>\n

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\u00a0\u00a0\u00a0* K-tuple\u7684\u5927\u5c0f\u4e00\u822c\u8bbe\u7f6e\u57282-6\u4e4b\u95f4\uff0c\u5177\u4f53\u53d6\u51b3\u4e8e\u5e8f\u5217\u7684\u957f\u5ea6\u548c\u53d8\u5f02\u6027\u3002\u901a\u5e38\u60c5\u51b5\u4e0b\uff0c\u8f83\u77ed\u7684K-tuple\u80fd\u591f\u66f4\u597d\u5730\u6355\u6349\u5e8f\u5217\u4e2d\u7684\u5c40\u90e8\u76f8\u4f3c\u6027\uff0c\u4f46\u53ef\u80fd\u4f1a\u5728\u6bd4\u5bf9\u8fc7\u7a0b\u4e2d\u4ea7\u751f\u8bef\u914d\u3002\u800c\u8f83\u957f\u7684K-tuple\u5219\u80fd\u591f\u66f4\u597d\u5730\u533a\u5206\u5e8f\u5217\u7684\u5dee\u5f02\uff0c\u4f46\u53ef\u80fd\u4f1a\u9519\u8fc7\u4e00\u4e9b\u76f8\u4f3c\u6027\u533a\u57df\u3002<\/p>\n

\u00a0\u00a0\u00a0\u00a0\u00a0*Gap penalty\u548cgap extension penalty\uff1a\u8fd9\u4e24\u4e2a\u53c2\u6570\u63a7\u5236\u7a7a\u4f4d\u7684\u7f5a\u5206\uff0c\u5373\u7a7a\u4f4d\u51fa\u73b0\u7684\u60e9\u7f5a\u7a0b\u5ea6\u3002\u4e00\u822c\u60c5\u51b5\u4e0b\uff0cgap penalty\u7684\u503c\u5e94\u8be5\u6bd4gap extension penalty\u9ad8\uff0c\u56e0\u4e3a\u5728\u5b9e\u9645\u751f\u7269\u5e8f\u5217\u4e2d\uff0c\u7a7a\u4f4d\u51fa\u73b0\u7684\u6982\u7387\u8f83\u4f4e\u3002\u5efa\u8bae\u521d\u59cb\u503c\u5206\u522b\u8bbe\u7f6e\u4e3a10\u548c0\u3002<\/p>\n

\u00a0\u00a0\u00a0* delay divergent seqs%”\u662f\u591a\u5e8f\u5217\u6bd4\u5bf9\u4e2d\u7684\u4e00\u4e2a\u53c2\u6570\uff0c\u5176\u4f5c\u7528\u662f\u63a7\u5236\u5728\u6bd4\u5bf9\u8fc7\u7a0b\u4e2d\u8df3\u8fc7\u9ad8\u5ea6\u5206\u6b67\u7684\u5e8f\u5217\uff0c\u4ee5\u51cf\u5c11\u8fd9\u4e9b\u5e8f\u5217\u5bf9\u6bd4\u5bf9\u7ed3\u679c\u7684\u5f71\u54cd\u3002<\/p>\n

\u5b8c\u6210\u4ee5\u540e\u7b49\u5f85\u7ed3\u679c\uff0c\u5728\u8fd9\u4e2a\u7a97\u53e3\u4e2d\uff0c\u53ef\u4ee5\u67e5\u770b\u5e8f\u5217\u7684\u6bd4\u5bf9\u7ed3\u679c\uff0c\u5305\u62ec\u6bd4\u5bf9\u5f97\u5206\u3001\u76f8\u4f3c\u6027\u77e9\u9635\u3001\u5e8f\u5217\u7684\u540c\u6e90\u6027\u7b49\u4fe1\u606f\u3002<\/p>\n

\u53ef\u4ee5\u4f7f\u7528\u201cFile\u201d\u83dc\u5355\u4e0b\u7684\u201cSave as\u201d\u9009\u9879\u5c06\u6bd4\u5bf9\u7ed3\u679c\u4fdd\u5b58\u4e3a\u6587\u672c\u6587\u4ef6\uff0c\u4e5f\u53ef\u4ee5\u9009\u4e2d\u7ed3\u679c\u540e\u4f7f\u7528\u201cEdit\u201d\u83dc\u5355\u4e0b\u7684\u201cCopy\u201d\u9009\u9879\u5c06\u6bd4\u5bf9\u7ed3\u679c\u590d\u5236\u5230\u526a\u8d34\u677f\u4e2d\uff0c\u4ee5\u4fbf\u4e8e\u5728\u5176\u4ed6\u8f6f\u4ef6\u4e2d\u8fdb\u884c\u5206\u6790\u548c\u5904\u7406\u3002<\/p>\n

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\u5230\u8fd9\u91cc\u6838\u9178\u6bd4\u5bf9\u5c31\u7ed3\u675f\u5566,\u53ef\u4ee5\u770b\u5230\u4fdd\u5b88\u6027\u6bd4\u8f83\u8f83\u9ad8\u7684\u533a\u57df\u90fd\u7528\u76f8\u540c\u7684\u8272\u5f69\u6807\u8bb0\u51fa\u6765\u4e86\uff0c\u79fb\u52a8\u4e0a\u65b9\u7684\u7ea2\u8272\u6846\u7ebf\u53ef\u4ee5\u67e5\u770b\u4e0d\u540c\u533a\u57df\u3002<\/p>\n

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\u5982\u679c\u4f60\u8fd8\u5728\u4e3a\u751f\u4fe1\u5206\u6790\u82e6\u607c\uff0c\u82e6\u82e6\u5b66\u4e60\u5374\u4e0d\u5f97\u8981\u9886\uff0c\u4e00\u5b9a\u8981\u8bd5\u4e00\u4e0b\u8fd9\u4e2a\u7ebf\u4e0a\u5e73\u53f0\uff0c\u4ec0\u4e48circos\u56fe\u3001\u5c0f\u63d0\u7434\u56fe\u3001\u66fc\u54c8\u987f\u56fe\u53ea\u8981\u4e0a\u4f20\u6570\u636e\u7edf\u7edf\u4e0d\u5728\u8bdd\u4e0b\uff01<\/p>\n

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\u751f\u4fe1\u4ebaR\u8bed\u8a00\u5b66\u4e60\u5fc5\u5907<\/span><\/strong><\/p>\n

\u7acb\u523b\u62e5\u6709\u4e00\u4e2aRstudio\u8d26\u53f7<\/span><\/strong><\/p>\n

\u5f00\u542f\u5347\u7ea7\u6a21\u5f0f\u5427<\/span><\/strong><\/p>\n

\uff0856\u7ebf\u7a0b\uff0c256G\u5185\u5b58\uff0c\u4e2a\u4eba\u5b58\u50a81T\uff09<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u9605\u8bfb\u539f\u6587<\/a><\/div>\n
\u9605\u8bfb\u539f\u6587<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u6709\u6211\u5728\uff0c\u522b\u5bb3\u6015\uff01\u5229\u7528DNAMAN\u8fdb\u884c\u6838\u9178\u6bd4\u5bf9\u7684\u6559\u7a0b\u6765\u5566~ \u539f\u521b\u00a0\u00a0\u5c0f\u679c\u00a0\u00a0\u751f\u4fe1\u679c\u00a0\u00a02023-04-15 19 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/48917"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=48917"}],"version-history":[{"count":2,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/48917\/revisions"}],"predecessor-version":[{"id":49016,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/48917\/revisions\/49016"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=48917"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=48917"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=48917"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}