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normal;\">\u968f\u7740\u5168\u57fa\u56e0\u7ec4\u5173\u8054\u5206\u6790\u4f7f\u7528\u6837\u672c\u6570\u91cf\u7684\u589e\u52a0\uff0c\u4eba\u4eec\u4e5f\u9010\u6e10\u8ba4\u8bc6\u5230\u5f88\u591a\u611f\u5174\u8da3\u7684\u6027\u72b6\u5728\u672c\u8d28\u4e0a\u662f\u7531\u5fae\u6548\u591a\u57fa\u56e0\u63a7\u5236\u3002\u901a\u8fc7\u4ee5\u6709\u751f\u7269\u5b66\u610f\u4e49\u7684\u65b9\u5f0f\u6574\u5408\u590d\u6742\u75be\u75c5\u7684\u4fe1\u606f\u7684\u57fa\u56e0\u4ee5\u53ca\u901a\u8def\u5206\u6790\uff0c\u662f\u5355\u53d8\u5f02GWAS\u7684\u6709\u6548\u8865\u5145\u3002\u5c0f\u56fe\u4eca\u5929\u5c06\u4ecb\u7ecdMAGMA\uff0c\u4e00\u4e2a\u57fa\u4e8e\u591a\u53d8\u91cf\u56de\u5f52\u6a21\u578b\u7684\u57fa\u56e0\u4ee5\u53ca\u901a\u8def\u5206\u6790\u5de5\u5177\u3002<\/p>\n<p style=\"text-indent: 0em;white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section 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54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>MAGMA\u7684\u57fa\u672c\u5206\u6790\u5305\u62ec\u4e24\u5230\u4e09\u4e2a\u6b65\u9aa4<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibPCWhM2nEmGibjKKEAsEp8JY1s7Gib2rhK3FwSrW7SkLCJFCNG2Hdm6zQ\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section 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style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSib73qPuUnump2AellibMQDSicl5eCzfdTQJzBo2hJncuHxGaYGcydMAfJw\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 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10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><span style=\"text-decoration: underline;\"><strong>\u7f51\u5740\u94fe\u63a5\uff1a<\/strong><\/span><\/p>\n<p style=\"white-space: normal;\">\uff08https:\/\/ctg.cncr.nl\/software\/magma\uff09<\/p>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 0em;white-space: normal;\">\u7a0b\u5e8f\u672c\u8eab\u7684\u4e0b\u8f7d\u94fe\u63a5\u4ee5\u53ca\u4e00\u4e9b\u8f85\u52a9\u6587\u4ef6\u53ef\u4ee5\u5728\u4e0b\u9762\u627e\u5230\u3002\u5bf9\u4e8eLinux\uff0c\u4e8c\u8fdb\u5236\u6587\u4ef6\u662f\u5728Debian\u4e0a\u7f16\u8bd1\u7684\uff0c\u4f46\u901a\u5e38\u4e5f\u4f1a\u5728\u5176\u4ed6\u53d1\u884c\u7248\u4e0a\u8fd0\u884c\u3002\u5982\u679c\u7531\u4e8eLinux\u53d1\u884c\u7248\u7684\u67d0\u4e9b\u5dee\u5f02\u800c\u65e0\u6cd5\u627e\u5230\u67d0\u4e9b\u5e93(\u901a\u5e38\u662f\u5173\u4e8e\u4e22\u5931.dll\u6587\u4ef6\u7684\u9519\u8bef\u6d88\u606f)\uff0c\u5219\u4f1a\u63d0\u4f9b\u989d\u5916\u7684\u9759\u6001\u94fe\u63a5\u4e8c\u8fdb\u5236\u6587\u4ef6;\u4f7f\u7528\u8fd9\u4e2a\u53ef\u4ee5\u89e3\u51b3\u8fd9\u4e2a\u95ee\u9898\u3002<\/p>\n<p style=\"text-indent: 0em;white-space: normal;\"><br \/><\/p>\n<p style=\"text-indent: 0em;white-space: normal;\">\u4e0b\u9762\u8fd8\u53ef\u4ee5\u4e0b\u8f7dMAGMA\u6e90\u4ee3\u7801\uff0c\u5982\u679c\u6240\u63d0\u4f9b\u7684\u4e8c\u8fdb\u5236\u6587\u4ef6\u4e0d\u652f\u6301\u7684\u8bdd\uff0c\u5b83\u53ef\u4ee5\u7528\u6765\u5728\u76ee\u6807\u7cfb\u7edf\u4e0a\u7f16\u8bd1\u7a0b\u5e8f(\u6ce8\u610f\uff0c\u9002\u7528\u6807\u51c6\u7248\u6743;MAGMA\u7684\u4e8c\u8fdb\u5236\u6587\u4ef6\u548c\u6e90\u4ee3\u7801\u4e0d\u80fd\u53d1\u5e03\u6216\u4fee\u6539)\u3002<\/p>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u6839\u636e\u81ea\u5df1\u9700\u6c42\u4e0b\u8f7d\u76f8\u5e94\u7248\u672c<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.3287037037037037\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_DSUP35jrK9YXKIyDbb1Jyg9eyTtrEw-3.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibichrDlERmgDpkFicjruPKibl4jwDSUP35jrK9YXKIyDbb1Jyg9eyTtrEw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSib73qPuUnump2AellibMQDSicl5eCzfdTQJzBo2hJncuHxGaYGcydMAfJw\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>\u6ce8\u91ca<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibPCWhM2nEmGibjKKEAsEp8JY1s7Gib2rhK3FwSrW7SkLCJFCNG2Hdm6zQ\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><strong>\u6ce8\u91ca\u53ef\u901a\u8fc7\u4ee5\u4e0b\u547d\u4ee4\u6267\u884c\uff1a<\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">magma --annotate --snp-loc [SNPLOC_FILE] --gene-loc [GENELOC_FILE] --out [ANNOT_PREFIX]<\/span><\/code><\/pre>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>[SNPLOC_FILE]\u9700\u8981\u7531\u6211\u4eec\u81ea\u5df1\u63d0\u4f9b<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.5409090909090909\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_ic0G4BulUruMYoNjw505ZicWMCUrCA-2.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibiahsNNuib1lqQpqicdpQeVxuy5t6oic0G4BulUruMYoNjw505ZicWMCUrCA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"220\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u6587\u4ef6\u5305\u542b\u4e09\u5217\uff0c\u5373\u524d\u4e09\u5217\u4e3aSNP ID, chromosome, \u548cbase pair position<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>[GENELOC_FILE]\u53ef\u4ee5\u4eceMAGMA\u7f51\u7ad9\u4e0b\u8f7d\uff0c\u7528\u4e8e\u4e0d\u540c\u7684\u6784\u5efa\u57fa\u56e0\u6ce8\u91ca\u53c2\u8003\u6587\u4ef6<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.24814814814814815\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_NP4qPv7uoMnB9vhyor8LdoZsMIL1Fw-2.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibAMmRklhiclPIaslDkOlAYhK9sNP4qPv7uoMnB9vhyor8LdoZsMIL1Fw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 0em;white-space: normal;\">\u5bf9\u4e8e\u57fa\u56e0\u5b9a\u4f4d\u6587\u4ef6\uff0c\u86cb\u767d\u8d28\u7f16\u7801\u57fa\u56e0\u7684\u57fa\u56e0\u5b9a\u4f4d\u4eceNCBI\u4f4d\u70b9\u83b7\u5f97\u3002\u5b9a\u4f4d\u5b9a\u4e49\u4e3a\u4ece\u8f6c\u5f55\u8d77\u59cb\u4f4d\u70b9\u5230\u8f6c\u5f55\u7ec8\u6b62\u4f4d\u70b9\u7684\u533a\u57df\u3002\u8fd9\u4e9b\u4f4d\u7f6e\u6587\u4ef6\u5305\u542bEntrez\u57fa\u56e0id\u3002<\/p>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSib73qPuUnump2AellibMQDSicl5eCzfdTQJzBo2hJncuHxGaYGcydMAfJw\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>\u57fa\u56e0\u5206\u6790<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibPCWhM2nEmGibjKKEAsEp8JY1s7Gib2rhK3FwSrW7SkLCJFCNG2Hdm6zQ\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><strong>SNP p\u503c\u5bf9SNP p\u503c\u8fdb\u884c\u57fa\u56e0\u5206\u6790\uff1a<\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">magma --bfile [REFDATA] --pval [PVAL_FILE] N=[N] --gene-annot [ANNOT_PREFIX].genes.annot --out [GENE_PREFIX]<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">[REFDATA] bfile\u4e3a\u539f\u59cb\u6570\u636e\u6216\u662f\u53c2\u8003LD\u9762\u677f\uff0c\u5982\u679c\u6570\u636e\u91cf\u4e0d\u5927\u53ef\u4ee5\u76f4\u63a5\u4f7f\u7528\u81ea\u5df1\u7684plink\u7684bed\u683c\u5f0f\u539f\u59cb\u6570\u636e\uff0c\u5728\u539f\u59cb\u6570\u636e\u65e0\u6cd5\u83b7\u5f97\u7684\u65f6\u5019\u53ef\u4ee5\u4f7f\u7528magma\u63d0\u4f9b\u76841000 genome\u53c2\u8003\u6570\u636e\uff0cbiobank\u7ea7\u522b\u7684\u6570\u636e\u7684\u60c5\u51b5\u4e0b\uff0c\u53ef\u4ee5\u968f\u673a\u62bd\u53d6\u67d0\u4e2a\u65cf\u88d4\u65e0\u4eb2\u7f18\u5173\u7cfb\u7684\u4e00\u5b9a\u4eba\u6570\uff08\u4f8b\u598220000\u4eba\uff09\u6765\u6784\u5efa\u81ea\u5df1\u7684\u53c2\u8003\u9762\u677f\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.337037037037037\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_0GohnSKFbFcBG6DIlrukZshU7He0bA-1.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibiaxIEus49rOKw2ynIEMQzgQ1V0GohnSKFbFcBG6DIlrukZshU7He0bA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 0em;white-space: normal;\">\u53c2\u8003\u6570\u636e\u6587\u4ef6\u662f\u4ece\u7b2c3\u9636\u6bb5\u76841000\u4e2a\u57fa\u56e0\u7ec4\u4e2d\u521b\u5efa\u7684\u3002\u6570\u636e\u4e2d\u7684SNP\u4f4d\u7f6e\u53c2\u8003\u4e86\u4eba\u7c7b\u57fa\u56e0\u7ec4Build 37\u3002\u8fd8\u6709\u4e00\u4e2a\u5305\u542b\u5b50\u79cd\u7fa4\u5b9a\u4e49\u7684\u9644\u52a0\u6587\u4ef6\uff0c\u53ef\u7528\u4e8e\u4ece1,000\u4e2a\u57fa\u56e0\u7ec4\u6570\u636e\u6587\u4ef6\u4e2d\u63d0\u53d6\u7279\u5b9a\u7684\u5b50\u79cd\u7fa4\u3002\u7279\u5b9a\u4e8e\u6570\u636e\u7684SNP\u540c\u4e49\u8bcd\u6587\u4ef6\u5305\u542b\u5728\u6570\u636e\u4e2d\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>[PVAL_FILE]\u7531\u6211\u4eec\u81ea\u5df1\u63d0\u4f9b<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u5305\u542b\u5148\u524d\u8ba1\u7b97\u7684SNP P\u503c\u7684\u6587\u4ef6(\u5728\u6587\u4ef6[PVAL_FILE]\u4e2d\u7684\u201cSNP\u201d\u548c\u201cP\u201d\u5217\u4e2d)\u3002<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.916030534351145\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_eia1xx05rKOWk0zarIowp7yPkIzZ7w-1.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibwQ6e6oTX0vS23vNy9ESqLZ7Z3eia1xx05rKOWk0zarIowp7yPkIzZ7w\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"131\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">pval\u4e3aSNP\u7684p\u503c\u6587\u4ef6\uff0c\u5305\u542b\u4e24\u5217 SNP \u4ee5\u53ca P<\/p>\n<p style=\"white-space: normal;\">[ANNOT_PREFIX]\u4e3a\u4e0a\u4e00\u6b65\u6ce8\u91ca\u540e\u5f97\u5230\u7684\u6587\u4ef6<\/p>\n<p style=\"white-space: normal;\">N\u4e3a\u6837\u672c\u91cf<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSib73qPuUnump2AellibMQDSicl5eCzfdTQJzBo2hJncuHxGaYGcydMAfJw\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>\u57fa\u56e0\u96c6\u5206\u6790<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibPCWhM2nEmGibjKKEAsEp8JY1s7Gib2rhK3FwSrW7SkLCJFCNG2Hdm6zQ\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><strong>\u8fdb\u884c\u57fa\u56e0\u96c6\u5206\u6790\uff1a<\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">magma --gene-results [GENE_PREFIX].genes.raw --<span class=\"code-snippet__built_in\">set<\/span>-annot [SET_FILE] --out [GS_PREFIX]<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u8bfb\u53d6\u5148\u524d\u6267\u884c\u7684\u57fa\u56e0\u5206\u6790\u7684\u7ed3\u679c\uff0c\u4ee5\u53ca\u5c06\u57fa\u56e0\u6620\u5c04\u5230\u6587\u4ef6[SET_FILE]\u4e2d\u6307\u5b9a\u7684\u57fa\u56e0\u96c6(\u6bcf\u884c\u5bf9\u5e94\u4e8e\u4e00\u4e2a\u57fa\u56e0\u96c6:\u57fa\u56e0\u96c6\u7684\u540d\u79f0\u540e\u8ddf\u57fa\u56e0id\uff0c\u4ee5\u7a7a\u683c\u5206\u9694)\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">[SET_FILE]\u4e3a\u57fa\u56e0\u96c6\u6216\u901a\u8def\u7684\u5b9a\u4e49\u6587\u4ef6\uff0c\u53ef\u4ee5\u76f4\u63a5\u4f7f\u7528MSigDB\u4e0b\u8f7d\u7684\u6587\u4ef6\uff08\u6ce8\u610f\u57fa\u56e0ID\u8981\u4e0e\u4e4b\u524d\u76f8\u5bf9\u5e94\uff09<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u9ed8\u8ba4\u8f93\u51fa\u4e09\u4e2a.gsa.out .gsa.genes.out, .gsa.sets.genes.out<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">.gsa.out \u4e3a\u6700\u4e3b\u8981\u7684\u8f93\u51fa\u6587\u4ef6\uff0c\u5305\u542b\u4e86\u5404\u4e2a\u901a\u8def\u7684\u68c0\u9a8c\u7ed3\u679c<\/p>\n<p style=\"white-space: normal;\">gsa.out \u5305\u542b\u4e86\u5404\u4e2a\u901a\u8def\u7684\u68c0\u9a8c\u7ed3\u679c<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.19537037037037036\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_6T6euYcWwQsuiaSuJOgRmkFIUiclgw-1.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibBlwX3heialwKdmz7Z7BxKw9FXFz6T6euYcWwQsuiaSuJOgRmkFIUiclgw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">gsa.genes.out \u57fa\u56e0\u5173\u8054\u7ed3\u679c<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.2222222222222222\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_d1BwK4dh9Rw9vlXic5wFAkNeKA8CTg-1.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibAhD2lO0u2Nu47y2zav2Oib5ylQd1BwK4dh9Rw9vlXic5wFAkNeKA8CTg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">gsa.sets.genes.out \u591a\u91cd\u68c0\u9a8c\u8c03\u6574\u540e, \u663e\u8457\u7684\u901a\u8def\u91cc\u7684\u57fa\u56e0\u7684\u4fe1\u606f<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.16296296296296298\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_ZY6rMYEsz5BEcsE6q7JK4GwicvE7Bw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibhyzgThlPa9gRvmbDU40LicgRT7ZY6rMYEsz5BEcsE6q7JK4GwicvE7Bw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.3888888888888889\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_ySIpbVxFh5tHVDuT9xcKFbKFLHZnlQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSib54sVs6EC31lrqsfVJiaflicBWqySIpbVxFh5tHVDuT9xcKFbKFLHZnlQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-bottom: 10px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(176, 176, 176);padding: 7px;\">\n<section style=\"justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgba(249, 238, 237, 0.5);padding: 18px;\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"text-align: justify;font-size: 14px;letter-spacing: 2px;line-height: 1.8;\">\n<p style=\"white-space: normal;\">\u6709\u7591\u95ee\u6b22\u8fce\u54a8\u8be2\u5c0f\u56fe\u7684\u5fae\u4fe1\u516c\u4f17\u53f7\uff08\u751f\u4fe1\u56fe\uff09\u548c\u4e91\u751f\u4fe1\u751f\u7269\u4fe1\u606f\u5b66\u5e73\u53f0\uff08 http:\/\/www.biocloudservice.com\/home.html\uff09<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<\/section>\n<section style=\"text-align: justify;font-size: 14px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u6b22\u8fce\u4f7f\u7528\uff1a\u4e91\u751f\u4fe1\u5e73\u53f0 ( http:\/\/www.biocloudservice.com\/home.html)<\/p>\n<\/section>\n<section style=\"transform: scale(0.5);transform-origin: center center;margin-top: -65px;margin-bottom: -65px;\" powered-by=\"xiumi.us\">\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"1\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/10_nmDUjQSDhQAwCebpp5Wx2zTPyb3ibg.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibEvQmicSEwPHnnicIHlibxHWetsQlnmDUjQSDhQAwCebpp5Wx2zTPyb3ibg\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"258\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"min-height: 40px;margin: 10px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"width: 100%;margin-right: auto;margin-bottom: -10px;margin-left: auto;\">\n<table width=\"100%\">\n<tbody>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:47.classicTable1:0\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:47.classicTable1:0.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;background-color: rgb(249, 174, 165);padding: 10px 0px;\" width=\"96.3700%\">\n<section style=\"line-height: 1;text-align: center;font-size: 17px;color: rgb(255, 255, 255);letter-spacing: 5px;\" powered-by=\"xiumi.us\">\n<p><strong>\u5f80\u671f\u63a8\u8350<\/strong><\/p>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:47.classicTable1:1\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:47.classicTable1:1.td@@0\" style=\"border-top: 0px none rgb(62, 62, 62);border-right: 0px none rgb(62, 62, 62);border-left: 0px none rgb(62, 62, 62);border-bottom-color: rgb(202, 198, 198);border-bottom-style: dashed;background-color: rgb(247, 247, 247);padding-right: 5px;padding-left: 5px;\" width=\"96.3700%\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: middle;border-width: 0px;align-self: center;flex: 0 0 auto;\">\n<section style=\"font-size: 14px;letter-spacing: 1px;\" powered-by=\"xiumi.us\">\n<p><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247485141&idx=1&sn=59b0df7b23a26f8a93ea394192e6344f&chksm=c1b17b28f6c6f23ecd9e87265e008d9ec1193582abf95fbe39f6e9eb8667ab8e34c391770b5d&scene=21#wechat_redirect\" textvalue=\"\u542c\u8bf4\u53ef\u4ee5\u7528R\u8bed\u8a00\u5b8c\u6210\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u9057\u4f20\u76f8\u5173\uff0c\u4f60\u6765\u4e0d\u6765\u5b66\uff1f\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" 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style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSib73qPuUnump2AellibMQDSicl5eCzfdTQJzBo2hJncuHxGaYGcydMAfJw\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>MAGMA\u7684\u57fa\u672c\u5206\u6790\u5305\u62ec\u4e24\u5230\u4e09\u4e2a\u6b65\u9aa4<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibPCWhM2nEmGibjKKEAsEp8JY1s7Gib2rhK3FwSrW7SkLCJFCNG2Hdm6zQ\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<ol style=\"padding-left: 40px;list-style-position: outside;\" class=\"list-paddingleft-1\">\n<li>\n<p>\u9996\u5148\uff0c\u5c06snp\u6620\u5c04\u5230\u57fa\u56e0\u4e0a\u7684\u6ce8\u91ca\u6b65\u9aa4;<\/p>\n<\/li>\n<li>\n<p>\u7b2c\u4e8c\u6b65\uff0c\u8fdb\u884c\u57fa\u56e0\u5206\u6790\uff0c\u8ba1\u7b97\u57fa\u56e0p\u503c;<\/p>\n<\/li>\n<li>\n<p>\u7b2c\u4e09\u6b65\uff0c\u57fa\u56e0\u6c34\u5e73\u5206\u6790\u6b65\u9aa4:\u8981\u4e48\u8fdb\u884c\u5e7f\u4e49\u57fa\u56e0\u96c6\u5206\u6790\uff0c\u8981\u4e48\u8fdb\u884c\u57fa\u56e0\u7279\u6027\u5206\u6790\uff0c\u8981\u4e48\u4e24\u8005\u517c\u800c\u6709\u4e4b\u3002\u57fa\u56e0\u6c34\u5e73\u5206\u6790\u90fd\u662f\u4ee5\u57fa\u56e0\u5206\u6790\u4e3a\u57fa\u7840\u7684\uff0c\u4efb\u4f55\u53ef\u80fd\u7684\u57fa\u56e0\u5206\u6790\u6a21\u578b\u90fd\u53ef\u4ee5\u4f5c\u4e3a\u57fa\u56e0\u6c34\u5e73\u5206\u6790\u7684\u8f93\u5165\u3002<\/p>\n<\/li>\n<\/ol>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSib73qPuUnump2AellibMQDSicl5eCzfdTQJzBo2hJncuHxGaYGcydMAfJw\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>\u9996\u5148\u4e0b\u8f7dMAGMA\u8f6f\u4ef6<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibPCWhM2nEmGibjKKEAsEp8JY1s7Gib2rhK3FwSrW7SkLCJFCNG2Hdm6zQ\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><span style=\"text-decoration: underline;\"><strong>\u7f51\u5740\u94fe\u63a5\uff1a<\/strong><\/span><\/p>\n<p style=\"white-space: normal;\">\uff08https:\/\/ctg.cncr.nl\/software\/magma\uff09<\/p>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 0em;white-space: normal;\">\u7a0b\u5e8f\u672c\u8eab\u7684\u4e0b\u8f7d\u94fe\u63a5\u4ee5\u53ca\u4e00\u4e9b\u8f85\u52a9\u6587\u4ef6\u53ef\u4ee5\u5728\u4e0b\u9762\u627e\u5230\u3002\u5bf9\u4e8eLinux\uff0c\u4e8c\u8fdb\u5236\u6587\u4ef6\u662f\u5728Debian\u4e0a\u7f16\u8bd1\u7684\uff0c\u4f46\u901a\u5e38\u4e5f\u4f1a\u5728\u5176\u4ed6\u53d1\u884c\u7248\u4e0a\u8fd0\u884c\u3002\u5982\u679c\u7531\u4e8eLinux\u53d1\u884c\u7248\u7684\u67d0\u4e9b\u5dee\u5f02\u800c\u65e0\u6cd5\u627e\u5230\u67d0\u4e9b\u5e93(\u901a\u5e38\u662f\u5173\u4e8e\u4e22\u5931.dll\u6587\u4ef6\u7684\u9519\u8bef\u6d88\u606f)\uff0c\u5219\u4f1a\u63d0\u4f9b\u989d\u5916\u7684\u9759\u6001\u94fe\u63a5\u4e8c\u8fdb\u5236\u6587\u4ef6;\u4f7f\u7528\u8fd9\u4e2a\u53ef\u4ee5\u89e3\u51b3\u8fd9\u4e2a\u95ee\u9898\u3002<\/p>\n<p style=\"text-indent: 0em;white-space: normal;\"><br \/><\/p>\n<p style=\"text-indent: 0em;white-space: normal;\">\u4e0b\u9762\u8fd8\u53ef\u4ee5\u4e0b\u8f7dMAGMA\u6e90\u4ee3\u7801\uff0c\u5982\u679c\u6240\u63d0\u4f9b\u7684\u4e8c\u8fdb\u5236\u6587\u4ef6\u4e0d\u652f\u6301\u7684\u8bdd\uff0c\u5b83\u53ef\u4ee5\u7528\u6765\u5728\u76ee\u6807\u7cfb\u7edf\u4e0a\u7f16\u8bd1\u7a0b\u5e8f(\u6ce8\u610f\uff0c\u9002\u7528\u6807\u51c6\u7248\u6743;MAGMA\u7684\u4e8c\u8fdb\u5236\u6587\u4ef6\u548c\u6e90\u4ee3\u7801\u4e0d\u80fd\u53d1\u5e03\u6216\u4fee\u6539)\u3002<\/p>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u6839\u636e\u81ea\u5df1\u9700\u6c42\u4e0b\u8f7d\u76f8\u5e94\u7248\u672c<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.3287037037037037\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_DSUP35jrK9YXKIyDbb1Jyg9eyTtrEw-3.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibichrDlERmgDpkFicjruPKibl4jwDSUP35jrK9YXKIyDbb1Jyg9eyTtrEw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSib73qPuUnump2AellibMQDSicl5eCzfdTQJzBo2hJncuHxGaYGcydMAfJw\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>\u6ce8\u91ca<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibPCWhM2nEmGibjKKEAsEp8JY1s7Gib2rhK3FwSrW7SkLCJFCNG2Hdm6zQ\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><strong>\u6ce8\u91ca\u53ef\u901a\u8fc7\u4ee5\u4e0b\u547d\u4ee4\u6267\u884c\uff1a<\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">magma --annotate --snp-loc [SNPLOC_FILE] --gene-loc [GENELOC_FILE] --out [ANNOT_PREFIX]<\/span><\/code><\/pre>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>[SNPLOC_FILE]\u9700\u8981\u7531\u6211\u4eec\u81ea\u5df1\u63d0\u4f9b<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.5409090909090909\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_ic0G4BulUruMYoNjw505ZicWMCUrCA-2.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibiahsNNuib1lqQpqicdpQeVxuy5t6oic0G4BulUruMYoNjw505ZicWMCUrCA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"220\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u6587\u4ef6\u5305\u542b\u4e09\u5217\uff0c\u5373\u524d\u4e09\u5217\u4e3aSNP ID, chromosome, \u548cbase pair position<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>[GENELOC_FILE]\u53ef\u4ee5\u4eceMAGMA\u7f51\u7ad9\u4e0b\u8f7d\uff0c\u7528\u4e8e\u4e0d\u540c\u7684\u6784\u5efa\u57fa\u56e0\u6ce8\u91ca\u53c2\u8003\u6587\u4ef6<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.24814814814814815\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_NP4qPv7uoMnB9vhyor8LdoZsMIL1Fw-2.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibAMmRklhiclPIaslDkOlAYhK9sNP4qPv7uoMnB9vhyor8LdoZsMIL1Fw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 0em;white-space: normal;\">\u5bf9\u4e8e\u57fa\u56e0\u5b9a\u4f4d\u6587\u4ef6\uff0c\u86cb\u767d\u8d28\u7f16\u7801\u57fa\u56e0\u7684\u57fa\u56e0\u5b9a\u4f4d\u4eceNCBI\u4f4d\u70b9\u83b7\u5f97\u3002\u5b9a\u4f4d\u5b9a\u4e49\u4e3a\u4ece\u8f6c\u5f55\u8d77\u59cb\u4f4d\u70b9\u5230\u8f6c\u5f55\u7ec8\u6b62\u4f4d\u70b9\u7684\u533a\u57df\u3002\u8fd9\u4e9b\u4f4d\u7f6e\u6587\u4ef6\u5305\u542bEntrez\u57fa\u56e0id\u3002<\/p>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSib73qPuUnump2AellibMQDSicl5eCzfdTQJzBo2hJncuHxGaYGcydMAfJw\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>\u57fa\u56e0\u5206\u6790<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibPCWhM2nEmGibjKKEAsEp8JY1s7Gib2rhK3FwSrW7SkLCJFCNG2Hdm6zQ\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><strong>SNP p\u503c\u5bf9SNP p\u503c\u8fdb\u884c\u57fa\u56e0\u5206\u6790\uff1a<\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">magma --bfile [REFDATA] --pval [PVAL_FILE] N=[N] --gene-annot [ANNOT_PREFIX].genes.annot --out [GENE_PREFIX]<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">[REFDATA] bfile\u4e3a\u539f\u59cb\u6570\u636e\u6216\u662f\u53c2\u8003LD\u9762\u677f\uff0c\u5982\u679c\u6570\u636e\u91cf\u4e0d\u5927\u53ef\u4ee5\u76f4\u63a5\u4f7f\u7528\u81ea\u5df1\u7684plink\u7684bed\u683c\u5f0f\u539f\u59cb\u6570\u636e\uff0c\u5728\u539f\u59cb\u6570\u636e\u65e0\u6cd5\u83b7\u5f97\u7684\u65f6\u5019\u53ef\u4ee5\u4f7f\u7528magma\u63d0\u4f9b\u76841000 genome\u53c2\u8003\u6570\u636e\uff0cbiobank\u7ea7\u522b\u7684\u6570\u636e\u7684\u60c5\u51b5\u4e0b\uff0c\u53ef\u4ee5\u968f\u673a\u62bd\u53d6\u67d0\u4e2a\u65cf\u88d4\u65e0\u4eb2\u7f18\u5173\u7cfb\u7684\u4e00\u5b9a\u4eba\u6570\uff08\u4f8b\u598220000\u4eba\uff09\u6765\u6784\u5efa\u81ea\u5df1\u7684\u53c2\u8003\u9762\u677f\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.337037037037037\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_0GohnSKFbFcBG6DIlrukZshU7He0bA-1.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibiaxIEus49rOKw2ynIEMQzgQ1V0GohnSKFbFcBG6DIlrukZshU7He0bA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 0em;white-space: normal;\">\u53c2\u8003\u6570\u636e\u6587\u4ef6\u662f\u4ece\u7b2c3\u9636\u6bb5\u76841000\u4e2a\u57fa\u56e0\u7ec4\u4e2d\u521b\u5efa\u7684\u3002\u6570\u636e\u4e2d\u7684SNP\u4f4d\u7f6e\u53c2\u8003\u4e86\u4eba\u7c7b\u57fa\u56e0\u7ec4Build 37\u3002\u8fd8\u6709\u4e00\u4e2a\u5305\u542b\u5b50\u79cd\u7fa4\u5b9a\u4e49\u7684\u9644\u52a0\u6587\u4ef6\uff0c\u53ef\u7528\u4e8e\u4ece1,000\u4e2a\u57fa\u56e0\u7ec4\u6570\u636e\u6587\u4ef6\u4e2d\u63d0\u53d6\u7279\u5b9a\u7684\u5b50\u79cd\u7fa4\u3002\u7279\u5b9a\u4e8e\u6570\u636e\u7684SNP\u540c\u4e49\u8bcd\u6587\u4ef6\u5305\u542b\u5728\u6570\u636e\u4e2d\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>[PVAL_FILE]\u7531\u6211\u4eec\u81ea\u5df1\u63d0\u4f9b<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u5305\u542b\u5148\u524d\u8ba1\u7b97\u7684SNP P\u503c\u7684\u6587\u4ef6(\u5728\u6587\u4ef6[PVAL_FILE]\u4e2d\u7684\u201cSNP\u201d\u548c\u201cP\u201d\u5217\u4e2d)\u3002<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.916030534351145\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_eia1xx05rKOWk0zarIowp7yPkIzZ7w-1.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibwQ6e6oTX0vS23vNy9ESqLZ7Z3eia1xx05rKOWk0zarIowp7yPkIzZ7w\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"131\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">pval\u4e3aSNP\u7684p\u503c\u6587\u4ef6\uff0c\u5305\u542b\u4e24\u5217 SNP \u4ee5\u53ca P<\/p>\n<p style=\"white-space: normal;\">[ANNOT_PREFIX]\u4e3a\u4e0a\u4e00\u6b65\u6ce8\u91ca\u540e\u5f97\u5230\u7684\u6587\u4ef6<\/p>\n<p style=\"white-space: normal;\">N\u4e3a\u6837\u672c\u91cf<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSib73qPuUnump2AellibMQDSicl5eCzfdTQJzBo2hJncuHxGaYGcydMAfJw\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>\u57fa\u56e0\u96c6\u5206\u6790<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibPCWhM2nEmGibjKKEAsEp8JY1s7Gib2rhK3FwSrW7SkLCJFCNG2Hdm6zQ\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><strong>\u8fdb\u884c\u57fa\u56e0\u96c6\u5206\u6790\uff1a<\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">magma --gene-results [GENE_PREFIX].genes.raw --<span class=\"code-snippet__built_in\">set<\/span>-annot [SET_FILE] --out [GS_PREFIX]<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u8bfb\u53d6\u5148\u524d\u6267\u884c\u7684\u57fa\u56e0\u5206\u6790\u7684\u7ed3\u679c\uff0c\u4ee5\u53ca\u5c06\u57fa\u56e0\u6620\u5c04\u5230\u6587\u4ef6[SET_FILE]\u4e2d\u6307\u5b9a\u7684\u57fa\u56e0\u96c6(\u6bcf\u884c\u5bf9\u5e94\u4e8e\u4e00\u4e2a\u57fa\u56e0\u96c6:\u57fa\u56e0\u96c6\u7684\u540d\u79f0\u540e\u8ddf\u57fa\u56e0id\uff0c\u4ee5\u7a7a\u683c\u5206\u9694)\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">[SET_FILE]\u4e3a\u57fa\u56e0\u96c6\u6216\u901a\u8def\u7684\u5b9a\u4e49\u6587\u4ef6\uff0c\u53ef\u4ee5\u76f4\u63a5\u4f7f\u7528MSigDB\u4e0b\u8f7d\u7684\u6587\u4ef6\uff08\u6ce8\u610f\u57fa\u56e0ID\u8981\u4e0e\u4e4b\u524d\u76f8\u5bf9\u5e94\uff09<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u9ed8\u8ba4\u8f93\u51fa\u4e09\u4e2a.gsa.out .gsa.genes.out, .gsa.sets.genes.out<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">.gsa.out \u4e3a\u6700\u4e3b\u8981\u7684\u8f93\u51fa\u6587\u4ef6\uff0c\u5305\u542b\u4e86\u5404\u4e2a\u901a\u8def\u7684\u68c0\u9a8c\u7ed3\u679c<\/p>\n<p style=\"white-space: normal;\">gsa.out \u5305\u542b\u4e86\u5404\u4e2a\u901a\u8def\u7684\u68c0\u9a8c\u7ed3\u679c<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.19537037037037036\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_6T6euYcWwQsuiaSuJOgRmkFIUiclgw-1.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibBlwX3heialwKdmz7Z7BxKw9FXFz6T6euYcWwQsuiaSuJOgRmkFIUiclgw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">gsa.genes.out \u57fa\u56e0\u5173\u8054\u7ed3\u679c<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.2222222222222222\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_d1BwK4dh9Rw9vlXic5wFAkNeKA8CTg-1.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibAhD2lO0u2Nu47y2zav2Oib5ylQd1BwK4dh9Rw9vlXic5wFAkNeKA8CTg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">gsa.sets.genes.out \u591a\u91cd\u68c0\u9a8c\u8c03\u6574\u540e, \u663e\u8457\u7684\u901a\u8def\u91cc\u7684\u57fa\u56e0\u7684\u4fe1\u606f<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.16296296296296298\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_ZY6rMYEsz5BEcsE6q7JK4GwicvE7Bw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qtn4SO6CwsicgjBibokEmxnSibhyzgThlPa9gRvmbDU40LicgRT7ZY6rMYEsz5BEcsE6q7JK4GwicvE7Bw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.3888888888888889\" data-s=\"300,640\" 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