{"id":50577,"date":"2024-06-16T09:52:28","date_gmt":"2024-06-16T01:52:28","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=50577"},"modified":"2024-06-16T09:52:28","modified_gmt":"2024-06-16T01:52:28","slug":"%e5%8d%81%e5%88%86%e9%92%9f%e5%ae%9e%e7%8e%b0kegg%e5%af%8c%e9%9b%86%e5%88%86%e6%9e%90%e5%a4%9a%e5%85%83%e5%8f%af%e8%a7%86%e5%8c%96-4","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=50577","title":{"rendered":"\u5341\u5206\u949f\u5b9e\u73b0KEGG\u5bcc\u96c6\u5206\u6790\u591a\u5143\u53ef\u89c6\u5316"},"content":{"rendered":"<p><html><br \/>\n<head><br \/>\n<title><\/title><br \/>\n<meta charset=\"utf-8\"><br \/>\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,maximum-scale=1.0,user-scalable=0,viewport-fit=cover\"><\/p>\n<style>\n*{margin:0;padding:0}html{-ms-text-size-adjust:100%;-webkit-text-size-adjust:100%;line-height:1.6}img{z-index:999;position:relative;max-width:100%;margin:10px 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ID\u8fdb\u884c\u6bd4\u5bf9\u30022\u3001\u4f7f\u7528\u7edf\u8ba1\u65b9\u6cd5\uff0c\u5982Fisher\u7cbe\u786e\u68c0\u9a8c\u6216\u8d85\u51e0\u4f55\u5206\u5e03\u6cd5\uff0c\u8ba1\u7b97\u5728\u7ed9\u5b9a\u57fa\u56e0\u6216\u86cb\u767d\u8d28\u5217\u8868\u73b0\u7279\u5b9a\u4ee3\u8c22\u901a\u8def\u6216\u529f\u80fd\u7684\u663e\u8457\u6027\u30023\u3001\u6839\u636e\u663e\u8457\u6027\u6c34\u5e73\u5bf9\u7ed3\u679c\u8fdb\u884c\u7b5b\u9009\uff0c\u786e\u5b9a\u5177\u6709\u751f\u7269\u5b66\u610f\u4e49\u7684\u901a\u8def\u6216\u529f\u80fd\u30024\u3001\u901a\u8fc7KEGG\u5bcc\u96c6\u5206\u6790\uff0c\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u8bc6\u522b\u4e0e\u7814\u7a76\u5bf9\u8c61\u76f8\u5173\u8054\u7684\u4ee3\u8c22\u901a\u8def\u3001\u4fe1\u53f7\u901a\u8def\u548c\u529f\u80fd\u6a21\u5757\uff0c\u4ece\u800c\u66f4\u597d\u5730\u7406\u89e3\u57fa\u56e0\u6216\u86cb\u767d\u8d28\u5728\u751f\u7269\u4f53\u5185\u7684\u4f5c\u7528\u548c\u8c03\u63a7\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;\">\u4eca\u5929\u5c0f\u679c\u5e26\u5927\u5bb6\u5b9e\u73b0KEGG\u7684\u5bcc\u96c6\u5206\u6790\uff5e<\/span><span style=\"\"><o:p><\/o:p><\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 20px;font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><em><strong><span style=\"font-family: \u9ed1\u4f53;\">\u4ee3\u7801\u5b9e\u73b0<\/span><\/strong><\/em><\/span><\/p>\n<h3><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 16px;\"><strong>\u8bfb\u5165\u4e00\u4e2a\u793a\u4f8b\u6570\u636e<\/strong><\/span><\/h3>\n<h2 style=\"font-size: 16px;text-align: center;\"><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;\"><o:p><\/o:p><\/span><\/h2>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"powershell\"><code><span class=\"code-snippet_outer\">data &lt;- read.delim(\"Downloads\/kegg_rich.txt\",header = T,na.strings = T)<\/span><\/code><code><span class=\"code-snippet_outer\"><br  \/><\/span><\/code><code><span class=\"code-snippet_outer\">#\u52a0\u8f7d\u76f8\u5e94\u7684\u8f6f\u4ef6\u5305<\/span><\/code><code><span class=\"code-snippet_outer\"><br  \/><\/span><\/code><code><span class=\"code-snippet_outer\">library(tidyverse)<\/span><\/code><code><span class=\"code-snippet_outer\"><br  \/><\/span><\/code><code><span class=\"code-snippet_outer\">colnames(data)<\/span><\/code><code><span class=\"code-snippet_outer\"><br  \/><\/span><\/code><code><span class=\"code-snippet_outer\">data_1&lt;-subset(data,p.adjust&lt;0.05)<\/span><\/code><code><span class=\"code-snippet_outer\"><br  \/><\/span><\/code><code><span class=\"code-snippet_outer\">colnames(data_1)<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.1069364161849711\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_E7dcGQB3viab8q6RFhicibsLZnzJ7A-5.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAwEDYcakdMibMcjoQxWlWTxGStsPGYTFTjZia5ucnf48frcJoREoE7dcGQB3viab8q6RFhicibsLZnzJ7A\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"692\" style=\"\"  data-recalc-dims=\"1\" \/><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;\">\u8fd8\u8bb0\u5f97\u5c0f\u679c\u5728\u8bb2R\u8bed\u8a00\u7684\u989c\u8272\u7684\u65f6\u5019\u7ed9\u5927\u5bb6\u5206\u4eab\u7684paletteer\u5305\u561b\uff0c\u8fd9\u91cc\u53ef\u4ee5\u5e94\u7528\u4e00\u4e0b\u5566\uff5e<\/span><span style=\"\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;\"><br  \/><\/span><\/p>\n<h3 style=\"text-align: center;\"><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><em><span style=\"font-size: 20px;\"><strong>\u6dfb\u52a0\u81ea\u5b9a\u4e49\u914d\u8272\u65b9\u6848\uff1a<\/strong><\/span><\/em><\/span><strong><span style=\"\"><o:p><\/o:p><\/span><\/strong><\/h3>\n<p><br  \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"bash\"><code><span class=\"code-snippet_outer\">library(paletteer)#\u914d\u8272\u5305<\/span><\/code><code><span class=\"code-snippet_outer\">d_palettes &lt;- palettes_d_names <\/span><\/code><code><span class=\"code-snippet_outer\">paletteer_d(\"ggthemes::wsj_dem_rep\",n=3) <\/span><\/code><code><span class=\"code-snippet_outer\">col_bar1&lt;-paletteer_d(\"ggthemes::wsj_dem_rep\",n=3) <\/span><\/code><code><span class=\"code-snippet_outer\">col_bar1<\/span><\/code><\/pre>\n<\/section>\n<p style=\"font-size: 16px;text-align: center;\"><br  \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.15421303656597773\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_eLuw0XvI6WNrlibEHpMiauib00XGtg-5.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAwEDYcakdMibMcjoQxWlWTxG9yZ0ic11ibQLcIyF7Bq3uicHfhvROleLuw0XvI6WNrlibEHpMiauib00XGtg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"629\" style=\"\"  data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<h3 style=\"text-align: center;\"><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><em><span style=\"font-size: 20px;\"><strong>\u753b\u56fe<\/strong><\/span><\/em><\/span><strong><span style=\"\"><o:p><\/o:p><\/span><\/strong><\/h3>\n<h4 style=\"text-align: left;\"><strong><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 16px;\">1\u3001\u6392\u5e8f\u67f1\u72b6\u56fe<\/span><\/strong><strong><span style=\"\"><o:p><\/o:p><\/span><\/strong><\/h4>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"javascript\"><code><span class=\"code-snippet_outer\">\u7b80\u5355\u7ed8\u5236\uff1a<\/span><\/code><code><span class=\"code-snippet_outer\">ggplot(data_1)+<\/span><\/code><code><span class=\"code-snippet_outer\">  geom_col(aes(x=Count,y=reorder(Description,Count),fill=pvalue),color='black',width = 0.6)<\/span><\/code><\/pre>\n<\/section>\n<p style=\"font-size: 16px;text-align: center;\"><br  \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.6193921852387844\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_OL4Hap38ibI11PwoLiccnrbibM4MNw-5.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAwEDYcakdMibMcjoQxWlWTxGSETib2X22bq6YeibbLXRzFk58VCvZOL4Hap38ibI11PwoLiccnrbibM4MNw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"691\" style=\"\"  data-recalc-dims=\"1\" \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"php\"><code><span class=\"code-snippet_outer\">\u6dfb\u52a0count\u3001\u989c\u8272\u3001\u548c\u4e3b\u9898<\/span><\/code><code><span class=\"code-snippet_outer\">ggplot(data_1)+<\/span><\/code><code><span class=\"code-snippet_outer\">  geom_col(aes(x=Count,y=reorder(Description,Count),fill=pvalue),color='black',width = 0.6)+<\/span><\/code><code><span class=\"code-snippet_outer\">  geom_text(aes(x=Count,y=reorder(Description,Count),label =Count),hjust=-0.5,vjust =0.5)+<\/span><\/code><code><span class=\"code-snippet_outer\">  scale_fill_gradientn(colours = c('#B1283AFF','#006A8EFF'))+<\/span><\/code><code><span class=\"code-snippet_outer\">  theme_minimal()+<\/span><\/code><code><span class=\"code-snippet_outer\">  scale_y_discrete(expand = c(0,0))+<\/span><\/code><code><span class=\"code-snippet_outer\">  geom_vline(xintercept = 0,lwd=0.1,color=\"black\")+<\/span><\/code><code><span class=\"code-snippet_outer\">  theme(legend.position = 'right')+ylab(NULL)<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.8106870229007633\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_NsyztQcicic4ZZ6ib6z8ZJfs6Ee0QA-5.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAwEDYcakdMibMcjoQxWlWTxGFln9PCZE42NMwhD3yuA5g9wyQKENsyztQcicic4ZZ6ib6z8ZJfs6Ee0QA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"655\" style=\"\"  data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<h4><span style=\"font-size: 16px;font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><strong>2\u3001\u5bcc\u96c6\u6c14\u6ce1\u56fe<\/strong><\/span><strong><span style=\"\"><o:p><\/o:p><\/span><\/strong><\/h4>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"php\"><code><span class=\"code-snippet_outer\">ggplot(data_1)+<\/span><\/code><code><span class=\"code-snippet_outer\">  geom_point(aes(x=Count,y=Description,color=pvalue,size=Count))+<\/span><\/code><code><span class=\"code-snippet_outer\">  scale_color_gradientn(colours = c('red','green'))+<\/span><\/code><code><span class=\"code-snippet_outer\">  theme_test()+<\/span><\/code><code><span class=\"code-snippet_outer\">  ylab(NULL)<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.6233766233766234\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_5SUD40dpODZ92NjYqGrqRFsOHbck2g-5.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAwEDYcakdMibMcjoQxWlWTxGWzWmplewmsiaVRdxo3cn3QYFk5SUD40dpODZ92NjYqGrqRFsOHbck2g\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\"  data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<h4><strong><span style=\"\">3<span style=\"font-family:\u9ed1\u4f53;\">\u3001<\/span><\/span><\/strong><strong><span style=\"\">\u5e26\u6709\u6807\u7b7e\u7684\u6c14\u6ce1\u56fe<\/span><\/strong><strong><span style=\"\"><o:p><\/o:p><\/span><\/strong><\/h4>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"php\"><code><span class=\"code-snippet_outer\">\u5229\u7528ggrepel\u4e2d\u7684geom_label_repel\u51fd\u6570<\/span><\/code><code><span class=\"code-snippet_outer\">#\u53d6\u4e00\u4e2a-log10\u53d8\u6210\u4e00\u5217<\/span><\/code><code><span class=\"code-snippet_outer\">data_1$logP&lt;- -log10(data_1$pvalue)<\/span><\/code><code><span class=\"code-snippet_outer\">library(ggrepel)<\/span><\/code><code><span class=\"code-snippet_outer\">col_bar2&lt;-paletteer_d(\"ggsci::default_igv\",n=50) #\u53bb\u53e6\u5916\u4e00\u4e2a\u8272\u5757\u7684\u989c\u8272<\/span><\/code><code><span class=\"code-snippet_outer\">col_bar2<\/span><\/code><code><span class=\"code-snippet_outer\"><br  \/><\/span><\/code><code><span class=\"code-snippet_outer\">colnames(data_1)<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.10115606936416185\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_0gAlvDuv3vqcBXfyjtEoSJiaVdkm7w-5.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAwEDYcakdMibMcjoQxWlWTxGxITHCGtNoAIZDOZoibm86sTbcic0gAlvDuv3vqcBXfyjtEoSJiaVdkm7w\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"692\" style=\"\"  data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"sql\"><code><span class=\"code-snippet_outer\">ggplot(data_1)+<\/span><\/code><code><span class=\"code-snippet_outer\">  geom_point(aes(x=logP,y=Description,size=Count,color=Description))+<\/span><\/code><code><span class=\"code-snippet_outer\">  scale_color_manual(values = col_bar2)+<\/span><\/code><code><span class=\"code-snippet_outer\">  theme_test()+<\/span><\/code><code><span class=\"code-snippet_outer\">  guides(color=F)+<\/span><\/code><code><span class=\"code-snippet_outer\">  geom_label_repel(aes(x=logP,y=Description,label=Description),<\/span><\/code><code><span class=\"code-snippet_outer\">                   size=4,nudge_y = 0.1)+<\/span><\/code><code><span class=\"code-snippet_outer\">  theme(axis.text.y = element_blank(),<\/span><\/code><code><span class=\"code-snippet_outer\">        axis.ticks.y = element_blank())+<\/span><\/code><code><span class=\"code-snippet_outer\">  xlim(c(min(data_1$logP)-2,max(data_1$logP)+2))+<\/span><\/code><code><span class=\"code-snippet_outer\">  xlab(bquote(-Log[10] ~ italic('Pvalue')))+ylab(bquote(italic('KEGG Pathway')))<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.6213872832369942\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_2WkT7EZU9zdicPaeicWduDRuxS6t6A-5.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAwEDYcakdMibMcjoQxWlWTxGBXdMYV1BFjrzN9B2ooqUJQraPy2WkT7EZU9zdicPaeicWduDRuxS6t6A\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"692\" style=\"\"  data-recalc-dims=\"1\" \/><\/p>\n<p><br  \/><\/p>\n<h3 style=\"text-align: center;\"><em><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 20px;\"><strong>KEGG\u5bcc\u96c6\u5206\u6790<\/strong><strong>\u4f5c\u7528<\/strong><\/span><\/em><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;\"><strong><o:p><\/o:p><\/strong><\/span><\/h3>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;\">\u529f\u80fd\u6ce8\u91ca\u548c\u89e3\u91ca\uff1aKEGG\u6570\u636e\u5e93\u63d0\u4f9b\u4e86\u8be6\u7ec6\u7684\u751f\u7269\u901a\u8def\u548c\u529f\u80fd\u6ce8\u91ca\u4fe1\u606f\uff0c\u901a\u8fc7KEGG\u5bcc\u96c6\u5206\u6790\u53ef\u4ee5\u786e\u5b9a\u57fa\u56e0\u96c6\u5408\u4e0e\u54ea\u4e9b\u751f\u7269\u5b66\u529f\u80fd\u3001\u4fe1\u53f7\u901a\u8def\u6216\u5316\u5b66\u53cd\u5e94\u76f8\u5173\u8054\u3002\u8fd9\u6709\u52a9\u4e8e\u7814\u7a76\u4eba\u5458\u7406\u89e3\u57fa\u56e0\u8868\u8fbe\u6570\u636e\u4e2d\u7684\u5173\u952e\u751f\u7269\u8fc7\u7a0b\u548c\u8c03\u63a7\u673a\u5236\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"text-decoration: underline;\"><strong><span style=\"text-decoration: underline;font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;color: rgb(0, 122, 170);\">1\u3001\u751f\u7269\u6807\u5fd7\u7269\u9274\u5b9a\uff1a<\/span><\/strong><\/span><span style=\"font-family: 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&quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;\">KEGG\u5bcc\u96c6\u5206\u6790\u7ed3\u679c\u53ef\u4ee5\u901a\u8fc7\u751f\u6210\u56fe\u5f62\u5316\u5c55\u793a\u6765\u66f4\u597d\u5730\u5448\u73b0\u3002\u4f8b\u5982\uff0c\u4f7f\u7528\u67f1\u72b6\u56fe\u3001\u6563\u70b9\u56fe\u6216\u7f51\u7edc\u56fe\u7b49\u65b9\u5f0f\u5c06\u5bcc\u96c6\u901a\u8def\/\u529f\u80fd\u53ca\u5176\u5173\u8054\u57fa\u56e0\u53ef\u89c6\u5316\uff0c\u6709\u52a9\u4e8e\u76f4\u89c2\u5730\u7406\u89e3\u6574\u4f53\u7ed3\u6784\u548c\u76f8\u4e92\u4f5c\u7528\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"text-decoration: underline;\"><strong><span style=\"text-decoration: underline;font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;color: rgb(0, 122, 170);\">3\u3001\u5047\u8bbe\u9a8c\u8bc1\u548c\u65b0\u5047\u8bbe\u751f\u6210\uff1a<\/span><\/strong><\/span><span style=\"font-family: 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rel=\"noopener\">4.\u5c0f\u679c\u5e26\u4f60\u7ed8\u5236ROC\u66f2\u7ebf\u8bc4\u4f30\u751f\u5b58\u9884\u6d4b\u80fd\u529b<\/a><\/section>\n<p><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.4255555555555556\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_lA0alvyBFuwtEUePcXp1OJsm3SqMWg-5.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAxweqRKIWbRUBSWSGID9aogUHbwOWZjeVWe1t2icZhtNofnVlA0alvyBFuwtEUePcXp1OJsm3SqMWg\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"900\"  data-recalc-dims=\"1\" \/><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: 0px;letter-spacing: 0.578px;white-space: normal;\">\n<p style=\"text-align: center;\"><br  \/><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: 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