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data-mpa-powered-by=\"yiban.io\">\n<section powered-by=\"xiumi.us\">\n<section>\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section>\n<section powered-by=\"xiumi.us\">\n<section powered-by=\"xiumi.us\">\n<section>\n<p><span style=\"font-size: 14px;letter-spacing: 0.034em;\">\u8981\u8c08\u8bba\u5230\u751f\u7269\u4fe1\u606f\u5b66\u5c31\u4e1a\u6700\u70ed\u95e8\u7684\u9886\u57df\uff0c\u836f\u7269\u5206\u5b50\u8bbe\u8ba1\u7edd\u5bf9\u662f\u7ed5\u4e0d\u5f00\u7684\u4e00\u5927\u8bdd\u9898\u3002\u53ef\u80fd\u5f88\u591a\u751f\u4fe1\u7684\u5c0f\u4f19\u4f34\u4eec\u8ba4\u4e3a\u751f\u4fe1\u7684\u4e3b\u8981\u5de5\u4f5c\u9886\u57df\u5728\u5404\u79cd\u6570\u636e\u7684\u5904\u7406\u548c\u6316\u6398\u4e2d\uff0c\u4ece\u800c\u5bf9\u836f\u7269\u5206\u5b50\u8bbe\u8ba1\u8fd9\u4e00\u9886\u57df\u6709\u4e9b\u964c\u751f\u3002\u4ece\u4eca\u5929\u5f00\u59cb\uff0c\u5c0f\u679c\u5c31\u7ed9\u5927\u5bb6\u5e26\u6765\u4e00\u7cfb\u5217\u8be6\u7ec6\u7684\u836f\u7269\u5206\u5b50\u8bbe\u8ba1\u6d41\u7a0b\u6559\u5b66\u3002\u5e9f\u8bdd\u4e0d\u591a\u8bf4\uff0c\u6211\u4eec\u76f4\u63a5\u5f00\u59cb\u5427\uff01<\/span><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><br \/><\/span><\/p>\n<h2 style=\"text-align: center;\"><span style=\"font-size: 20px;\"><em><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><strong>\u4ec0\u4e48\u662fDiscovery Studio\uff1f<\/strong><\/span><\/em><\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><strong><span style=\"color: rgb(79, 129, 189);font-size: 14pt;\"><o:p><\/o:p><\/span><\/strong><\/span><\/h2>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">Discovery Studio\u662f\u7531DNASTAR\u516c\u53f8\u5f00\u53d1\u7684\u4e00\u5957\u96c6\u6210\u7684\u8ba1\u7b97\u5316\u5b66\u548c\u5206\u5b50\u5efa\u6a21\u8f6f\u4ef6\u5957\u4ef6\u3002\u5b83\u88ab\u5e7f\u6cdb\u7528\u4e8e\u836f\u7269\u7814\u53d1\u3001\u86cb\u767d\u8d28\u7814\u7a76\u3001\u751f\u7269\u5206\u5b50\u6a21\u62df\u7b49\u9886\u57df\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">Discovery Studio\u5177\u6709\u4e30\u5bcc\u7684\u529f\u80fd\u548c\u5de5\u5177\uff0c\u53ef\u7528\u4e8e\u836f\u7269\u8bbe\u8ba1\u3001\u865a\u62df\u7b5b\u9009\u3001\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u3001\u5206\u5b50\u52a8\u529b\u5b66\u6a21\u62df\u7b49\u4efb\u52a1\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5371428571428571\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_YuVdicAt5IwgXVu63ed0gB7k7pfJBw-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5QrobOjxPwT1MFcsjyTYaeM4AyYuVdicAt5IwgXVu63ed0gB7k7pfJBw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u4e0b\u9762\u5c0f\u679c\u7ed9\u5927\u5bb6\u5e26\u6765\u4e86Discovery Studio\u7684\u4e00\u4e9b\u5e38\u89c1\u7684\u529f\u80fd\u548c\u6a21\u5757\u4ecb\u7ecd\uff1a<o:p><\/o:p><\/span><\/p>\n<p><span style=\"text-decoration: underline;\"><strong><span style=\"text-decoration: underline;font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;color: rgb(61, 170, 214);\">LigandFit\uff08\u5206\u5b50\u5bf9\u63a5\u548c\u878d\u5408\uff09<\/span><\/strong><\/span><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\uff1a\u8be5\u6a21\u5757\u53ef\u7528\u4e8e\u836f\u7269\u8bbe\u8ba1\u548c\u865a\u62df\u7b5b\u9009\u3002\u5b83\u5141\u8bb8\u7814\u7a76\u4eba\u5458\u5c06\u5c0f\u5206\u5b50\uff08\u836f\u7269\u5019\u9009\u7269\uff09\u4e0e\u86cb\u767d\u8d28\u9776\u70b9\u8fdb\u884c\u5bf9\u63a5\uff0c\u4ee5\u9884\u6d4b\u5b83\u4eec\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u548c\u7ed3\u5408\u80fd\u529b\u3002\u6b64\u5916\uff0cLigandFit\u8fd8\u652f\u6301\u5206\u5b50\u878d\u5408\u6280\u672f\uff0c\u7528\u4e8e\u5728\u5df2\u77e5\u914d\u4f53\u7684\u57fa\u7840\u4e0a\u751f\u6210\u65b0\u7684\u5206\u5b50\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"text-decoration: underline;color: rgb(61, 170, 214);\"><strong><span style=\"text-decoration: underline;font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">Sequence Viewer\uff08\u86cb\u767d\u8d28\u5e8f\u5217\u5206\u6790\u548c\u6bd4\u8f83\uff09<\/span><\/strong><\/span><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\uff1a\u8be5\u6a21\u5757\u53ef\u7528\u4e8e\u5206\u6790\u548c\u6bd4\u8f83\u86cb\u767d\u8d28\u5e8f\u5217\u3002\u5b83\u63d0\u4f9b\u4e86\u591a\u4e2a\u5de5\u5177\uff0c\u5305\u62ec\u591a\u5e8f\u5217\u6bd4\u5bf9\u3001\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u548c\u529f\u80fd\u6ce8\u91ca\u3002\u901a\u8fc7Sequence Viewer\uff0c\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u786e\u5b9a\u86cb\u767d\u8d28\u5e8f\u5217\u4e4b\u95f4\u7684\u5171\u540c\u7279\u5f81\uff0c\u5e76\u63a8\u65ad\u5b83\u4eec\u4e4b\u95f4\u7684\u7ed3\u6784\u548c\u529f\u80fd\u5173\u7cfb\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"text-decoration: underline;\"><strong><span style=\"text-decoration: underline;font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;color: rgb(61, 170, 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style=\"text-decoration: underline;\"><strong><span style=\"text-decoration: underline;font-size: 14px;color: rgb(61, 170, 214);\">GCG<\/span><\/strong><strong><span style=\"text-decoration: underline;font-size: 14px;color: rgb(61, 170, 214);\">\uff08\u751f\u7269\u5e8f\u5217\u5206\u6790\uff09<\/span><\/strong><\/span><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, 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Studio\u7684\u5f3a\u5927\u4e4b\u5904\uff0c\u662f\u4e0d\u662f\u5df2\u7ecf\u8feb\u4e0d\u53ca\u5f85\u60f3\u77e5\u9053\u5177\u4f53\u5982\u4f55\u4f7f\u7528\u5b83\u4e86\u5462\uff1f\u73b0\u5728\u5c31\u8ddf\u4e0a\u5c0f\u679c\u7684\u8282\u594f\uff0c\u8fc5\u901f\u8d70\u8fd1\u5b83\uff01<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><br \/><\/span><\/p>\n<h2 style=\"text-align: center;\"><span style=\"font-size: 20px;\"><em><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><strong>\u7ed8\u5236\u5c0f\u5206\u5b50\u914d\u4f53<\/strong><\/span><\/em><\/span><strong><span style=\"font-family: Calibri;color: rgb(79, 129, 189);font-size: 14pt;\"><o:p><\/o:p><\/span><\/strong><\/h2>\n<p style=\"text-align: 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data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5357142857142857\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_cnpyqngLnKoXY2ibdsaGbRXLByEhQA-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q59z1ZdpiaSH5fcwgYXser2tibSs4icnpyqngLnKoXY2ibdsaGbRXLByEhQA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, 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src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_X2l25jHbUtqic7p8g4vzvbPEuF4J4A-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5IsyuXIUE6FCZVz4S46TB8cZDUX2l25jHbUtqic7p8g4vzvbPEuF4J4A\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"360\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-size: 14px;\"><span style=\"font-family: Cambria;\">\u5982\u56fe\u5c0f\u679c\u6807\u51fa\u7684\u94c5\u7b14\u6309\u94ae\u53ef\u4ee5\u7528\u6765\u7ed8\u5236\u539f\u5b50\u548c\u5316\u5b66\u952e\uff0c\u5c0f\u679c\u5728\u8fd9\u91cc\u753b\u4e86\u4e00\u4e2a\u4e94\u5143\u73af\u4e3a\u4f8b\uff0c\u7ed9\u5927\u5bb6\u5c55\u793a\u4e00\u4e0b\u7ed8\u5236\u5c0f\u5206\u5b50\u57fa\u672c\u6846\u67b6\u7684\u65b9\u6cd5\u3002<\/span><span style=\"font-family: Cambria;font-size: 12pt;\"><o:p><\/o:p><\/span><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: Cambria;\"><br 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style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5371428571428571\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_SotibMfYTGS7qGRudtqN0SMkjZRGuw-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5hNvtGGF9xhxAgUFVVYUA1jMveSotibMfYTGS7qGRudtqN0SMkjZRGuw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-size: 14px;\"><span style=\"font-family: Cambria;\">\u6211\u4eec\u4e5f\u53ef\u4ee5\u9009\u4e2d\u67d0\u4e2a\u539f\u5b50\u6216\u5316\u5b66\u952e\u540e\uff0c\u70b9\u51fb\u4e0a\u65b9\u7684chemistry\u6309\u94ae\u62c9\u5f00\u83dc\u5355\uff0c\u5728\u8fd9\u91cc\u53ef\u4ee5\u8fdb\u884c\u6dfb\u52a0\u6c22\u539f\u5b50\u3001\u6539\u53d8\u9009\u4e2d\u539f\u5b50\u7684\u5143\u7d20\u7c7b\u578b\u3001\u6539\u53d8\u6742\u5316\u8f68\u9053\u7c7b\u578b\u3001\u6539\u53d8\u539f\u5b50\u5316\u5408\u4ef7\u3001\u6539\u53d8\u539f\u5b50\u6c27\u5316\u6001\u7b49\u7b49\u64cd\u4f5c\uff0c\u5c0f\u4f19\u4f34\u4eec\u53ef\u4ee5\u4e00\u4e00\u63a2\u7d22\u54e6~\u5c0f\u679c\u5728\u8fd9\u91cc\u628a\u9009\u4e2d\u7684C\u539f\u5b50\u66f4\u6539\u6210\u4e86N\u539f\u5b50\u3002<\/span><span style=\"font-family: Cambria;font-size: 12pt;\"><o:p><\/o:p><\/span><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: Cambria;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5371428571428571\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_kWYvibCwngEcTrDluK8yo0qLasjJYQ-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5Eb8XNHpuvaL7lsLicy0rLocGJAkWYvibCwngEcTrDluK8yo0qLasjJYQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-family: Cambria;font-size: 14px;\">\u5728\u5c0f\u4f19\u4f34\u4eec\u8c03\u6574\u5b8c\u81ea\u5df1\u521b\u5efa\u7684\u5c0f\u5206\u5b50\u540e\uff0c\u53ef\u4ee5\u5982\u56fe\u8fdb\u884c\u4f18\u5316\u4e09\u7ef4\u7ed3\u6784\u7684\u64cd\u4f5c\uff0c\u4e0b\u9762\u4e09\u5f20\u56fe\u5206\u522b\u662f\u4f18\u5316\u524d\uff0c\u4f18\u5316\u4e86\u9009\u4e2d\u7684N\u539f\u5b50\u540e\u4ee5\u53ca\u5bf9\u6574\u4f53\u5206\u5b50\u8fdb\u884c\u4f18\u5316\u540e\u7684\u7ed3\u679c\uff0c\u5c0f\u4f19\u4f34\u4eec\u53ef\u4ee5\u611f\u53d7\u4e00\u4e0b\u4f18\u5316\u524d\u540e\u662f\u4e0d\u662f\u786e\u5b9e\u6709\u6240\u4e0d\u540c\u5462~<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: Cambria;font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5357142857142857\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_TWg5ygiaYh9pt2BVO9wibG8tw3QqbQ-3.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5mU0V5gDtTkLqBDYrFsR9T4qt8ibTWg5ygiaYh9pt2BVO9wibG8tw3QqbQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5357142857142857\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/10_UIdATuvWMP1CbhIFmarQrQ4pKiaZuQ-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5OHnjKXoRGDv4ustocxicibKcwb8UIdATuvWMP1CbhIFmarQrQ4pKiaZuQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5357142857142857\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/11_ut9G1n9JCOa38wicicvBmiahlvEsmA-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5uTx8oqzxNiboAc1zzAvWMS6O80fibut9G1n9JCOa38wicicvBmiahlvEsmA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: Cambria;font-size: 14px;\">\u6211\u4eec\u4e5f\u53ef\u4ee5\u6309\u4f4f\u9f20\u6807\u53f3\u952e\u8fdb\u884c\u62d6\u52a8\u6765\u66f4\u6362\u89c2\u5bdf\u89d2\u5ea6\uff1a<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: Cambria;font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5342857142857143\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/12_IZz0DtQ5wSAjZibxFHX02rDQWnw3XA-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5v4wIPTWlvJ7UCDwT8SDURblDyIZz0DtQ5wSAjZibxFHX02rDQWnw3XA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-family: Cambria;font-size: 14px;\">\u4ee5\u4e0a\u5c31\u662f\u6211\u4eec\u5728Discovery studio\u81ea\u5df1\u7ed8\u5236\u5c0f\u5206\u5b50\u914d\u4f53\u5e76\u8fdb\u884c\u8c03\u6574\u4f18\u5316\u7684\u8fc7\u7a0b\u5566\uff0c\u4f46\u662f\u5f88\u591a\u5c0f\u4f19\u4f34\u53ef\u80fd\u4f1a\u6bd4\u8f83\u719f\u6089\u5728\u522b\u7684\u5e73\u53f0\u6216\u8f6f\u4ef6\u8fdb\u884c\u7ed8\u5236\u5c0f\u5206\u5b50\uff0c\u6216\u8005\u76f4\u63a5\u5bfc\u5165\u73b0\u6709\u7684\u5c0f\u5206\u5b50\u6765\u8fdb\u884c\u64cd\u4f5c\uff0c\u90a3\u4e48\u4e0b\u9762\u5c0f\u679c\u5c31\u7ed9\u5927\u5bb6\u5c55\u793a\u4e00\u4e0b\u5982\u4f55\u5bf9\u5bfc\u5165\u7684\u6bd4\u8f83\u590d\u6742\u7684\u5c0f\u5206\u5b50\u8fdb\u884c\u64cd\u4f5c\u5427~<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><br \/><\/p>\n<h2 style=\"text-align: center;\"><em><span style=\"font-size: 20px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><strong>\u4f18\u5316\u5bfc\u5165\u7684\u914d\u4f53<\/strong><\/span><\/em><em><span style=\"font-size: 20px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><strong><span style=\"font-family: Calibri;color: rgb(79, 129, 189);font-size: 14pt;\"><o:p><\/o:p><\/span><\/strong><\/span><\/em><\/h2>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5357142857142857\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/13_MHlVlfqspg8FewRBvXuuCWLKrCtxfQ-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5HHcF5HBZ1v9AjfAa6pm95QMibMHlVlfqspg8FewRBvXuuCWLKrCtxfQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p><span style=\"font-size: 14px;font-family: Cambria;\"><br \/><\/span><\/p>\n<p><span style=\"font-family: Cambria;font-size: 14px;\">\u5982\u56fe\u4ecefile->open\u53ef\u4ee5\u9009\u62e9\u6253\u5f00\u672c\u5730\u5c0f\u5206\u5b50\u6587\u4ef6<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 20px;\"><em><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><strong><br \/><\/strong><\/span><\/em><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5342857142857143\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/14_q1Fkn8UpkDN7gncDGMnDuFea7IMTCg-3.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5ohicLSY1BHnmWE0zarbkm1a8Oq1Fkn8UpkDN7gncDGMnDuFea7IMTCg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u5982\u56fe\u70b9\u51fbSmall Molecules>Prepare or Filter Ligands>Prepare Ligands\uff0c\u53ef\u4ee5\u6253\u5f00\u53c2\u6570\u8bbe\u7f6e\u9762\u677f\uff1b\u8bbe\u7f6eInput Ligands \u53c2\u6570\u4e3a’\u6587\u4ef6\u540d:All’\uff0c\u5373\u8868\u793a\u5bf9\u6240\u6709\u7684\u5c0f\u5206\u5b50\u8fdb\u884c\u5904\u7406\uff0c\u5176\u4f59\u53c2\u6570\u4e00\u822c\u9ed8\u8ba4\uff0c\u968f\u540e\u70b9\u51fbRUN\u8fd0\u884c\u3002<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5371428571428571\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/15_Cib7I9icLtIoqic8KDgFTblia6rdGw-3.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5MibC3jaBQgibJe6eF4PTWz4AbshdFMCib7I9icLtIoqic8KDgFTblia6rdGw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u8fd0\u884c\u7ed3\u675f\u540e\uff0c\u6211\u4eec\u53ef\u4ee5\u5728\u5f39\u51fa\u7684\u7a97\u53e3\u70b9\u51fbreport\u6765\u67e5\u770b\u5904\u7406\u4fe1\u606f\uff0c\u70b9\u51fb\u53f3\u4fa7\u7684view result\u540e\u5c31\u4f1a\u5f39\u51fa\u5de6\u4fa7\u7684\u754c\u9762\u89c2\u5bdf\u5904\u7406\u7ed3\u679c\u3002<o:p><\/o:p><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5342857142857143\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/16_l73pyrTLR8hAFqUOI1FJovAG6ibeFQ-3.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5dZ0fn81Y09KYgmx3gaw4ZKh72l73pyrTLR8hAFqUOI1FJovAG6ibeFQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5371428571428571\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/17_6ZbJ4ibibu50roEzqIPNObiaL8iaHA-3.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5FqLLyv3OAhib9IDiaia8lDxk951ibkick6ZbJ4ibibu50roEzqIPNObiaL8iaHA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u5c0f\u4f19\u4f34\u4eec\u53ef\u80fd\u8fd8\u4e0d\u77e5\u9053\u8fd9\u4e00\u6b65\u64cd\u4f5c\u6709\u4ec0\u4e48\u4f5c\u7528\uff0c\u5c0f\u679c\u5728\u8fd9\u91cc\u7ed9\u5927\u5bb6\u89e3\u91ca\u4e00\u4e0b\uff1a\u901a\u8fc7”Prepare Ligands”\u529f\u80fd\uff0c\u53ef\u4ee5\u5bf9\u5c0f\u5206\u5b50\u8fdb\u884c\u4ee5\u4e0b\u64cd\u4f5c\uff1a<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u6e05\u6d01\u5316\u5408\u7269\u7ed3\u6784\uff1a\u4fee\u590d\u5c0f\u5206\u5b50\u4e2d\u7684\u7ed3\u6784\u95ee\u9898\uff0c\u5982\u4fee\u590d\u952e\u8fde\u63a5\u9519\u8bef\u3001\u586b\u8865\u7f3a\u5931\u539f\u5b50\u6216\u4fee\u6b63\u539f\u5b50\u7684\u5f62\u5f0f\u7535\u8377\u7b49\uff0c\u786e\u4fdd\u5206\u5b50\u7ed3\u6784\u7684\u6b63\u786e\u6027\u548c\u4e00\u81f4\u6027\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u6dfb\u52a0\u6c22\u539f\u5b50\uff1a\u4e3a\u4e86\u8fdb\u884c\u5206\u5b50\u529b\u573a\u8ba1\u7b97\u548c\u5176\u4ed6\u76f8\u5e94\u8ba1\u7b97\uff0c\u901a\u5e38\u9700\u8981\u5728\u5c0f\u5206\u5b50\u4e0a\u6dfb\u52a0\u9002\u5f53\u7684\u6c22\u539f\u5b50\u3002”Prepare Ligands”\u529f\u80fd\u53ef\u4ee5\u81ea\u52a8\u6dfb\u52a0\u6c22\u539f\u5b50\uff0c\u5e76\u8c03\u6574\u5176\u4f4d\u7f6e\uff0c\u4ee5\u4f7f\u5f97\u5206\u5b50\u80fd\u591f\u5728\u529b\u573a\u8ba1\u7b97\u4e2d\u5f97\u5230\u6b63\u786e\u7684\u63cf\u8ff0\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u79bb\u5b50\u5316\u5904\u7406\uff1a\u8be5\u529f\u80fd\u53ef\u4ee5\u5c06\u5c0f\u5206\u5b50\u7684\u79bb\u5b50\u72b6\u6001\u8fdb\u884c\u4fee\u6b63\uff0c\u5728\u6a21\u62df\u548c\u8ba1\u7b97\u8fc7\u7a0b\u4e2d\u8003\u8651\u6eb6\u5242\u548c\u79bb\u5b50\u7684\u6548\u5e94\u3002\u4f8b\u5982\uff0c\u53ef\u4ee5\u5bf9\u5c0f\u5206\u5b50\u8fdb\u884c\u8d28\u5b50\u5316\u6216\u53bb\u8d28\u5b50\u5316\u5904\u7406\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u80fd\u91cf\u6700\u5c0f\u5316\uff1a”Prepare Ligands”\u8fd8\u63d0\u4f9b\u4e86\u80fd\u91cf\u6700\u5c0f\u5316\u7684\u9009\u9879\uff0c\u4ee5\u8fdb\u4e00\u6b65\u4f18\u5316\u5c0f\u5206\u5b50\u7684\u6784\u8c61\u548c\u6027\u80fd\u3002\u901a\u8fc7\u80fd\u91cf\u6700\u5c0f\u5316\uff0c\u53ef\u4ee5\u5bfb\u627e\u5c0f\u5206\u5b50\u7684\u6700\u7a33\u5b9a\u6784\u8c61\uff0c\u8bc4\u4f30\u5176\u80fd\u91cf\u548c\u51e0\u4f55\u53c2\u6570\uff0c\u5e76\u4e3a\u540e\u7eed\u8ba1\u7b97\u63d0\u4f9b\u66f4\u53ef\u9760\u7684\u8d77\u70b9\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u6211\u4eec\u8fd8\u53ef\u4ee5\u901a\u8fc7Small Molecules|Minimize Ligands>Full Minimization\u6309\u94ae\u6267\u884c\u5c0f\u5206\u5b50\u7684\u5168\u80fd\u91cf\u6700\u5c0f\u5316\u8ba1\u7b97\uff0c\u8c03\u6574\u539f\u5b50\u7684\u4f4d\u7f6e\u548c\u952e\u957f\u3001\u89d2\u5ea6\u7b49\u53c2\u6570\uff0c\u5e2e\u52a9\u4f18\u5316\u5206\u5b50\u7684\u51e0\u4f55\u5f62\u72b6\u548c\u7a7a\u95f4\u6392\u5e03\uff0c\u5bfb\u627e\u5c0f\u5206\u5b50\u7684\u6700\u7a33\u5b9a\u6784\u8c61\u3002<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5342857142857143\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/18_G1Z4j0Jn0xTe98muaGzKU1JPCXlLmQ-3.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5EawdqibNDckJD5bCZwwkMoTCLG1Z4j0Jn0xTe98muaGzKU1JPCXlLmQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u4f9d\u7136\u662f\u8bbe\u7f6eInput Ligands \u53c2\u6570\u4e3a’\u6587\u4ef6\u540d:All’\uff0c\u5176\u4f59\u53c2\u6570\u9ed8\u8ba4\uff0c\u968f\u540e\u70b9\u51fbRUN\u8fd0\u884c\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u8fd0\u884c\u7ed3\u675f\u540e\uff0c\u6211\u4eec\u53ef\u4ee5\u4ece\u8f6f\u4ef6\u6700\u4e0b\u65b9\u7684jobs\u4e2d\u627e\u5230\u6211\u4eec\u8fdb\u884c\u8fc7\u7684\u64cd\u4f5c\uff0c\u70b9\u51fb\u5373\u53ef\u6253\u5f00\u5df2\u7ecf\u5b8c\u6210\u8fc7\u7684\u64cd\u4f5c\u7ed3\u679c\u5566\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5371428571428571\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/19_wV5DEqic2mEUMDicT9jqNPzticUlbg-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5zVy0EO8yrTjvUt8JlNtu9xJLkduwV5DEqic2mEUMDicT9jqNPzticUlbg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u5c0f\u4f19\u4f34\u4eec\u53ef\u4ee5\u70b9\u51fb\u53f3\u4fa7\u7a97\u53e3\u6700\u4e0b\u9762\u7684view results\u6765\u66f4\u76f4\u89c2\u5730\u89c2\u770b\u7ed3\u679c\uff0c\u968f\u540e\u5c31\u4f1a\u5f39\u51fa\u5de6\u4fa7\u7ed3\u679c\u7a97\u53e3\uff0c\u6211\u4eec\u4e5f\u53ef\u4ee5\u8fdb\u884c\u62d6\u52a8\u7b49\u64cd\u4f5c\u6765\u89c2\u5bdf\u7ed3\u679c\u3002<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5357142857142857\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/20_ahlulMMicRdsnPMyCITuaicVCNU0AA-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5K2aCEJEOT5kDDAdGpJicJYGN2EPahlulMMicRdsnPMyCITuaicVCNU0AA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><span style=\"font-size: 14px;\">\u5230\u8fd9\u91cc\u4e3a\u6b62\uff0c\u914d\u4f53\u8bbe\u8ba1\u7684\u6700\u4e3b\u8981\u6d41\u7a0b\u5c31\u5df2\u7ecf\u5b8c\u6210\u5566\uff0c\u600e\u4e48\u6837\uff0c\u662f\u4e0d\u662f\u975e\u5e38\u7b80\u5355\u5462\uff1f\u7ec6\u5fc3\u7684\u5c0f\u4f19\u4f34\u53ef\u80fd\u5df2\u7ecf\u6ce8\u610f\u5230\uff0c\u5f53\u6211\u4eec\u628a\u9f20\u6807\u653e\u5230<\/span>discovery studio\u7684\u5927\u591a\u6570\u6309\u94ae\u4e0a\u65f6\uff0c\u4f1a\u51fa\u73b0help\u6309\u94ae\uff0c\u5728\u4f7f\u7528\u8fc7\u7a0b\u4e2d\u5c0f\u4f19\u4f34\u4eec\u5982\u679c\u6709\u4ec0\u4e48\u7591\u95ee\u4e00\u5b9a\u8981\u591a\u67e5\u770bhelp\u54e6\uff0c\u53ea\u6709\u6df1\u5165\u4e86\u89e3\u539f\u7406\u548c\u5177\u4f53\u64cd\u4f5c\u6b65\u9aa4\u624d\u80fd\u5b8c\u6210\u5408\u683c\u7684\u836f\u7269\u8bbe\u8ba1\u3002<o:p><\/o:p><\/span><\/p>\n<p style=\"text-align: left;\"><span style=\"text-align: left;letter-spacing: 0.034em;\"><\/span><span style=\"text-align: left;letter-spacing: 0.578px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u5c0f\u4f19\u4f34\u6709\u6ca1\u6709\u5fc3\u52a8\u5462\uff0c\u5feb\u53bb\u8bd5\u8bd5\u5427\uff0c\u4e0d\u8981\u5fd8\u8bb0\u591a\u591a\u7406\u89e3\u4ee3\u7801\u7684\u610f\u4e49\uff0c\u8fd9\u6837\u624d\u80fd\u5957\u7528\u81ea\u5df1\u6570\u636e\u8fdb\u884c\u5c55\u793a\u3002<\/span><strong style=\"text-align: left;color: rgb(121, 123, 170);font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;outline: 0px;font-size: 15px;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);\">\u4ee5\u4e0b\u63a8\u8350\u7684\u662f\u4e00\u4e2a\u591a\u529f\u80fd\u7684\u751f\u4fe1\u5e73\u53f0\uff0c\u70b9\u51fb\u539f\u6587\u7acb\u523b\u4e86\u89e3~<\/strong><br \/><\/p>\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><\/span><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: 0px;letter-spacing: 0.578px;white-space: normal;\">\n<section style=\"font-size: 16px;\">\n<section powered-by=\"xiumi.us\" style=\"margin: 10px;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\">\n<section style=\"padding-right: 10px;padding-left: 10px;display: 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tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">2.\u6bd4blast\u8fd8\u4f18\u79c0\u7684\u5e8f\u5217\u6bd4\u5bf9\u5de5\u5177\uff1fHMMER\u6765\u4e86<\/a><\/section>\n<section style=\"letter-spacing: 0.578px;line-height: 1.75em;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247491909&idx=1&sn=902e34bcf53e605fba2b457ec6a33e36&chksm=cf7f7180f808f8961542f458a49da14e85d8831449fb65fbf2623d55affc564686a5422f56fd&scene=21#wechat_redirect\" textvalue=\"3.\u5bf9\u5355\u7ec6\u80de\u5206\u6790\u6beb\u65e0\u5934\u7eea\uff1f\u8ba9popsicleR\u9886\u4f60\u5165\u95e8\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">3.\u5bf9\u5355\u7ec6\u80de\u5206\u6790\u6beb\u65e0\u5934\u7eea\uff1f\u8ba9popsicleR\u9886\u4f60\u5165\u95e8<\/a><\/section>\n<section style=\"letter-spacing: 0.578px;line-height: 1.75em;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247491905&idx=1&sn=fb34ebd6282962c7803badaee7a39096&chksm=cf7f7184f808f8929608c0050344ad86193d0fc6455c1c18e16cc17bf4b37832b63d3b18284e&scene=21#wechat_redirect\" textvalue=\"4.\u5c0f\u679c\u5e26\u4f60\u7ed8\u5236ROC\u66f2\u7ebf\u8bc4\u4f30\u751f\u5b58\u9884\u6d4b\u80fd\u529b\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">4.\u5c0f\u679c\u5e26\u4f60\u7ed8\u5236ROC\u66f2\u7ebf\u8bc4\u4f30\u751f\u5b58\u9884\u6d4b\u80fd\u529b<\/a><\/section>\n<p><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;\"><br \/><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: 0px;letter-spacing: 0.578px;white-space: normal;\">\n<section style=\"letter-spacing: 0.578px;caret-color: rgba(0, 0, 0, 0);font-size: 16px;\">\n<section>\n<section style=\"margin-bottom: 8px;font-size: 32px;color: rgb(0, 150, 136);\">\n<p style=\"text-indent: 0em;line-height: 1.75em;\"><span style=\"letter-spacing: 0.5px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247493050&idx=2&sn=ee0643e61ad49d9da96fc5ead974bd8b&chksm=cf7f757ff808fc69c274f50b85b15bb7afae13df06337fb3cdc26bfb38fbc17b8bc48b37e65a&scene=21#wechat_redirect\" textvalue=\"\u4f60\u5df2\u9009\u4e2d\u4e86\u6dfb\u52a0\u94fe\u63a5\u7684\u5185\u5bb9\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"1\" rel=\"noopener\"><span class=\"js_jump_icon h5_image_link\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.4255555555555556\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/21_3enDMf2LD6pjia3zQolKXIfTwuh6AA-4.jpg?w=640\" 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14pt;\"><o:p><\/o:p><\/span><\/strong><\/span><\/h2>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">Discovery Studio\u662f\u7531DNASTAR\u516c\u53f8\u5f00\u53d1\u7684\u4e00\u5957\u96c6\u6210\u7684\u8ba1\u7b97\u5316\u5b66\u548c\u5206\u5b50\u5efa\u6a21\u8f6f\u4ef6\u5957\u4ef6\u3002\u5b83\u88ab\u5e7f\u6cdb\u7528\u4e8e\u836f\u7269\u7814\u53d1\u3001\u86cb\u767d\u8d28\u7814\u7a76\u3001\u751f\u7269\u5206\u5b50\u6a21\u62df\u7b49\u9886\u57df\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">Discovery Studio\u5177\u6709\u4e30\u5bcc\u7684\u529f\u80fd\u548c\u5de5\u5177\uff0c\u53ef\u7528\u4e8e\u836f\u7269\u8bbe\u8ba1\u3001\u865a\u62df\u7b5b\u9009\u3001\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u3001\u5206\u5b50\u52a8\u529b\u5b66\u6a21\u62df\u7b49\u4efb\u52a1\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5371428571428571\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_YuVdicAt5IwgXVu63ed0gB7k7pfJBw-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5QrobOjxPwT1MFcsjyTYaeM4AyYuVdicAt5IwgXVu63ed0gB7k7pfJBw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u4e0b\u9762\u5c0f\u679c\u7ed9\u5927\u5bb6\u5e26\u6765\u4e86Discovery Studio\u7684\u4e00\u4e9b\u5e38\u89c1\u7684\u529f\u80fd\u548c\u6a21\u5757\u4ecb\u7ecd\uff1a<o:p><\/o:p><\/span><\/p>\n<p><span style=\"text-decoration: underline;\"><strong><span style=\"text-decoration: underline;font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;color: rgb(61, 170, 214);\">LigandFit\uff08\u5206\u5b50\u5bf9\u63a5\u548c\u878d\u5408\uff09<\/span><\/strong><\/span><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, 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14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\uff1a\u8be5\u6a21\u5757\u53ef\u7528\u4e8e\u5206\u6790\u548c\u6bd4\u8f83\u86cb\u767d\u8d28\u5e8f\u5217\u3002\u5b83\u63d0\u4f9b\u4e86\u591a\u4e2a\u5de5\u5177\uff0c\u5305\u62ec\u591a\u5e8f\u5217\u6bd4\u5bf9\u3001\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u548c\u529f\u80fd\u6ce8\u91ca\u3002\u901a\u8fc7Sequence Viewer\uff0c\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u786e\u5b9a\u86cb\u767d\u8d28\u5e8f\u5217\u4e4b\u95f4\u7684\u5171\u540c\u7279\u5f81\uff0c\u5e76\u63a8\u65ad\u5b83\u4eec\u4e4b\u95f4\u7684\u7ed3\u6784\u548c\u529f\u80fd\u5173\u7cfb\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"text-decoration: underline;\"><strong><span style=\"text-decoration: underline;font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;color: rgb(61, 170, 214);\">QSAR\u6a21\u5757\uff08\u5b9a\u91cf\u6784\u6548\u5173\u7cfb\uff09<\/span><\/strong><\/span><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\uff1a\u8be5\u6a21\u5757\u4e3b\u8981\u7528\u4e8e\u6784\u5efa\u548c\u9884\u6d4b\u5b9a\u91cf\u6784\u6548\u5173\u7cfb\u6a21\u578b\u3002\u501f\u52a9QSAR\u6a21\u5757\uff0c\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u6839\u636e\u5206\u5b50\u7684\u7ed3\u6784\u548c\u6d3b\u6027\u6570\u636e\u8fdb\u884c\u6a21\u578b\u8bad\u7ec3\uff0c\u5e76\u4f7f\u7528\u6b64\u6a21\u578b\u9884\u6d4b\u65b0\u5316\u5408\u7269\u7684\u751f\u7269\u6d3b\u6027\u3002\u8fd9\u6709\u52a9\u4e8e\u52a0\u5feb\u836f\u7269\u7814\u53d1\u8fc7\u7a0b\uff0c\u7b5b\u9009\u51fa\u5177\u6709\u6f5c\u5728\u836f\u7269\u6d3b\u6027\u7684\u5316\u5408\u7269\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"text-decoration: underline;color: rgb(61, 170, 214);\"><strong><span style=\"text-decoration: underline;font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">CHARMm\uff08\u5206\u5b50\u52a8\u529b\u5b66\u6a21\u62df\uff09<\/span><\/strong><\/span><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\uff1a\u8be5\u6a21\u5757\u53ef\u7528\u4e8e\u8fdb\u884c\u5206\u5b50\u52a8\u529b\u5b66\u6a21\u62df\uff0c\u6a21\u62df\u86cb\u767d\u8d28\u3001\u6838\u9178\u548c\u5c0f\u5206\u5b50\u5728\u6c34\u6eb6\u6db2\u4e2d\u7684\u52a8\u6001\u884c\u4e3a\u3002\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u901a\u8fc7CHARMm\u6a21\u5757\u4e86\u89e3\u5206\u5b50\u7684\u6784\u8c61\u6f14\u53d8\u3001\u76f8\u4e92\u4f5c\u7528\u4ee5\u53ca\u5176\u4e0e\u73af\u5883\u4e4b\u95f4\u7684\u5f71\u54cd\u3002\u8fd9\u5bf9\u4e8e\u7406\u89e3\u86cb\u767d\u8d28\u529f\u80fd\u548c\u836f\u7269-\u9776\u70b9\u76f8\u4e92\u4f5c\u7528\u673a\u5236\u81f3\u5173\u91cd\u8981\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"text-decoration: underline;\"><strong><span style=\"text-decoration: underline;font-size: 14px;color: rgb(61, 170, 214);\">GCG<\/span><\/strong><strong><span style=\"text-decoration: underline;font-size: 14px;color: rgb(61, 170, 214);\">\uff08\u751f\u7269\u5e8f\u5217\u5206\u6790\uff09<\/span><\/strong><\/span><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\uff1aGCG\u6a21\u5757\u662f\u4e00\u4e2a\u5f3a\u5927\u7684\u5de5\u5177\uff0c\u7528\u4e8e\u5206\u6790\u548c\u5904\u7406\u751f\u7269\u5e8f\u5217\u6570\u636e\uff0c\u5305\u62ecDNA\u3001RNA\u548c\u86cb\u767d\u8d28\u5e8f\u5217\u3002\u5b83\u5305\u62ec\u591a\u4e2a\u8ba1\u7b97\u5de5\u5177\uff0c\u5982\u6bd4\u5bf9\u5de5\u5177\u3001\u641c\u7d22\u5de5\u5177\u548c\u6ce8\u91ca\u5de5\u5177\uff0c\u65b9\u4fbf\u4e86\u7814\u7a76\u4eba\u5458\u5bf9\u751f\u7269\u5e8f\u5217\u8fdb\u884c\u7cbe\u786e\u7684\u5206\u6790\u548c\u89e3\u91ca\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u901a\u8fc7\u4e0a\u9762\u51e0\u4e2a\u529f\u80fd\u7684\u4ecb\u7ecd\uff0c\u5c0f\u679c\u76f8\u4fe1\u5c0f\u4f19\u4f34\u4eec\u5df2\u7ecf\u521d\u6b65\u7406\u89e3\u4e86Discovery Studio\u7684\u5f3a\u5927\u4e4b\u5904\uff0c\u662f\u4e0d\u662f\u5df2\u7ecf\u8feb\u4e0d\u53ca\u5f85\u60f3\u77e5\u9053\u5177\u4f53\u5982\u4f55\u4f7f\u7528\u5b83\u4e86\u5462\uff1f\u73b0\u5728\u5c31\u8ddf\u4e0a\u5c0f\u679c\u7684\u8282\u594f\uff0c\u8fc5\u901f\u8d70\u8fd1\u5b83\uff01<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><br \/><\/span><\/p>\n<h2 style=\"text-align: center;\"><span style=\"font-size: 20px;\"><em><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><strong>\u7ed8\u5236\u5c0f\u5206\u5b50\u914d\u4f53<\/strong><\/span><\/em><\/span><strong><span style=\"font-family: Calibri;color: rgb(79, 129, 189);font-size: 14pt;\"><o:p><\/o:p><\/span><\/strong><\/h2>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5357142857142857\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_pyoO7N5HRMrobpSWynyE84lgZyRR5A-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5GcwsWNfY7qM8tENibsgvGQAYTpyoO7N5HRMrobpSWynyE84lgZyRR5A\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5342857142857143\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_gMrSicPZicRVdhG8Eeb9ZvicNgam6A-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q52qvdg3ibWDtZ5TfG4WAYPj13NzpGgMrSicPZicRVdhG8Eeb9ZvicNgam6A\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5357142857142857\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_cnpyqngLnKoXY2ibdsaGbRXLByEhQA-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q59z1ZdpiaSH5fcwgYXser2tibSs4icnpyqngLnKoXY2ibdsaGbRXLByEhQA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u5982\u56fe\u6240\u793a\uff0c\u5c0f\u679c\u5148\u65b0\u5efa\u4e86\u4e00\u4e2a\u5c0f\u5206\u5b50\u7a97\u53e3\uff0c\u968f\u540e\u518dview->toolbar\u4e2d\u52fe\u9009sketching\u548cview\u4e24\u4e2a\u9009\u9879\uff0c\u8fd9\u6837\u6211\u4eec\u5c31\u53ef\u4ee5\u901a\u8fc7\u5de6\u4e0a\u89d2\u7684\u5de5\u5177\u680f\u6309\u6211\u4eec\u7684\u5fc3\u610f\u521b\u5efa\u5c0f\u5206\u5b50\u5566<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.25555555555555554\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_X2l25jHbUtqic7p8g4vzvbPEuF4J4A-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5IsyuXIUE6FCZVz4S46TB8cZDUX2l25jHbUtqic7p8g4vzvbPEuF4J4A\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"360\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-size: 14px;\"><span style=\"font-family: Cambria;\">\u5982\u56fe\u5c0f\u679c\u6807\u51fa\u7684\u94c5\u7b14\u6309\u94ae\u53ef\u4ee5\u7528\u6765\u7ed8\u5236\u539f\u5b50\u548c\u5316\u5b66\u952e\uff0c\u5c0f\u679c\u5728\u8fd9\u91cc\u753b\u4e86\u4e00\u4e2a\u4e94\u5143\u73af\u4e3a\u4f8b\uff0c\u7ed9\u5927\u5bb6\u5c55\u793a\u4e00\u4e0b\u7ed8\u5236\u5c0f\u5206\u5b50\u57fa\u672c\u6846\u67b6\u7684\u65b9\u6cd5\u3002<\/span><span style=\"font-family: Cambria;font-size: 12pt;\"><o:p><\/o:p><\/span><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: Cambria;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5357142857142857\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_y6WIsWq7GcWDgIbcibn5fcruwjlEjQ-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q563F6KTFgWj0NV1WQAVjSeRphVy6WIsWq7GcWDgIbcibn5fcruwjlEjQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: Cambria;font-size: 14px;\">\u5982\u679c\u6211\u4eec\u60f3\u6539\u53d8\u5316\u5b66\u952e\uff0c\u53ef\u4ee5\u5148\u5728\u5de6\u4e0a\u89d2\u5207\u6362\u81f3\u7bad\u5934\u56fe\u6807\u6765\u9009\u62e9\u60f3\u8981\u6539\u53d8\u7684\u952e\uff0c\u968f\u540e\u9f20\u6807\u53f3\u51fb\u6253\u5f00\u83dc\u5355\uff0c\u5728bond\u83dc\u5355\u4e2d\u5bf9\u5316\u5b66\u952e\u7684\u7c7b\u578b\u8fdb\u884c\u8c03\u6574\u3002\u5728\u8fd9\u4e2a\u53f3\u952e\u62c9\u5f00\u7684\u83dc\u5355\u4e2d\u6211\u4eec\u8fd8\u53ef\u4ee5\u8fdb\u884c\u6539\u53d8\u67d0\u4e2a\u952e\u6216\u539f\u5b50\u663e\u793a\u989c\u8272\u6216\u6dfb\u52a0\u5907\u6ce8\u7b49\u7b49\u5176\u4ed6\u64cd\u4f5c\u3002<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 20px;\"><em><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><strong><br \/><\/strong><\/span><\/em><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5371428571428571\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_SotibMfYTGS7qGRudtqN0SMkjZRGuw-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5hNvtGGF9xhxAgUFVVYUA1jMveSotibMfYTGS7qGRudtqN0SMkjZRGuw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-size: 14px;\"><span style=\"font-family: Cambria;\">\u6211\u4eec\u4e5f\u53ef\u4ee5\u9009\u4e2d\u67d0\u4e2a\u539f\u5b50\u6216\u5316\u5b66\u952e\u540e\uff0c\u70b9\u51fb\u4e0a\u65b9\u7684chemistry\u6309\u94ae\u62c9\u5f00\u83dc\u5355\uff0c\u5728\u8fd9\u91cc\u53ef\u4ee5\u8fdb\u884c\u6dfb\u52a0\u6c22\u539f\u5b50\u3001\u6539\u53d8\u9009\u4e2d\u539f\u5b50\u7684\u5143\u7d20\u7c7b\u578b\u3001\u6539\u53d8\u6742\u5316\u8f68\u9053\u7c7b\u578b\u3001\u6539\u53d8\u539f\u5b50\u5316\u5408\u4ef7\u3001\u6539\u53d8\u539f\u5b50\u6c27\u5316\u6001\u7b49\u7b49\u64cd\u4f5c\uff0c\u5c0f\u4f19\u4f34\u4eec\u53ef\u4ee5\u4e00\u4e00\u63a2\u7d22\u54e6~\u5c0f\u679c\u5728\u8fd9\u91cc\u628a\u9009\u4e2d\u7684C\u539f\u5b50\u66f4\u6539\u6210\u4e86N\u539f\u5b50\u3002<\/span><span style=\"font-family: Cambria;font-size: 12pt;\"><o:p><\/o:p><\/span><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: Cambria;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5371428571428571\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_kWYvibCwngEcTrDluK8yo0qLasjJYQ-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5Eb8XNHpuvaL7lsLicy0rLocGJAkWYvibCwngEcTrDluK8yo0qLasjJYQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-family: Cambria;font-size: 14px;\">\u5728\u5c0f\u4f19\u4f34\u4eec\u8c03\u6574\u5b8c\u81ea\u5df1\u521b\u5efa\u7684\u5c0f\u5206\u5b50\u540e\uff0c\u53ef\u4ee5\u5982\u56fe\u8fdb\u884c\u4f18\u5316\u4e09\u7ef4\u7ed3\u6784\u7684\u64cd\u4f5c\uff0c\u4e0b\u9762\u4e09\u5f20\u56fe\u5206\u522b\u662f\u4f18\u5316\u524d\uff0c\u4f18\u5316\u4e86\u9009\u4e2d\u7684N\u539f\u5b50\u540e\u4ee5\u53ca\u5bf9\u6574\u4f53\u5206\u5b50\u8fdb\u884c\u4f18\u5316\u540e\u7684\u7ed3\u679c\uff0c\u5c0f\u4f19\u4f34\u4eec\u53ef\u4ee5\u611f\u53d7\u4e00\u4e0b\u4f18\u5316\u524d\u540e\u662f\u4e0d\u662f\u786e\u5b9e\u6709\u6240\u4e0d\u540c\u5462~<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: Cambria;font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5357142857142857\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_TWg5ygiaYh9pt2BVO9wibG8tw3QqbQ-3.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5mU0V5gDtTkLqBDYrFsR9T4qt8ibTWg5ygiaYh9pt2BVO9wibG8tw3QqbQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5357142857142857\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/10_UIdATuvWMP1CbhIFmarQrQ4pKiaZuQ-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5OHnjKXoRGDv4ustocxicibKcwb8UIdATuvWMP1CbhIFmarQrQ4pKiaZuQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5357142857142857\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/11_ut9G1n9JCOa38wicicvBmiahlvEsmA-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5uTx8oqzxNiboAc1zzAvWMS6O80fibut9G1n9JCOa38wicicvBmiahlvEsmA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: Cambria;font-size: 14px;\">\u6211\u4eec\u4e5f\u53ef\u4ee5\u6309\u4f4f\u9f20\u6807\u53f3\u952e\u8fdb\u884c\u62d6\u52a8\u6765\u66f4\u6362\u89c2\u5bdf\u89d2\u5ea6\uff1a<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: Cambria;font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5342857142857143\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/12_IZz0DtQ5wSAjZibxFHX02rDQWnw3XA-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5v4wIPTWlvJ7UCDwT8SDURblDyIZz0DtQ5wSAjZibxFHX02rDQWnw3XA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-family: Cambria;font-size: 14px;\">\u4ee5\u4e0a\u5c31\u662f\u6211\u4eec\u5728Discovery studio\u81ea\u5df1\u7ed8\u5236\u5c0f\u5206\u5b50\u914d\u4f53\u5e76\u8fdb\u884c\u8c03\u6574\u4f18\u5316\u7684\u8fc7\u7a0b\u5566\uff0c\u4f46\u662f\u5f88\u591a\u5c0f\u4f19\u4f34\u53ef\u80fd\u4f1a\u6bd4\u8f83\u719f\u6089\u5728\u522b\u7684\u5e73\u53f0\u6216\u8f6f\u4ef6\u8fdb\u884c\u7ed8\u5236\u5c0f\u5206\u5b50\uff0c\u6216\u8005\u76f4\u63a5\u5bfc\u5165\u73b0\u6709\u7684\u5c0f\u5206\u5b50\u6765\u8fdb\u884c\u64cd\u4f5c\uff0c\u90a3\u4e48\u4e0b\u9762\u5c0f\u679c\u5c31\u7ed9\u5927\u5bb6\u5c55\u793a\u4e00\u4e0b\u5982\u4f55\u5bf9\u5bfc\u5165\u7684\u6bd4\u8f83\u590d\u6742\u7684\u5c0f\u5206\u5b50\u8fdb\u884c\u64cd\u4f5c\u5427~<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><br \/><\/p>\n<h2 style=\"text-align: center;\"><em><span style=\"font-size: 20px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><strong>\u4f18\u5316\u5bfc\u5165\u7684\u914d\u4f53<\/strong><\/span><\/em><em><span style=\"font-size: 20px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><strong><span style=\"font-family: Calibri;color: rgb(79, 129, 189);font-size: 14pt;\"><o:p><\/o:p><\/span><\/strong><\/span><\/em><\/h2>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5357142857142857\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/13_MHlVlfqspg8FewRBvXuuCWLKrCtxfQ-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5HHcF5HBZ1v9AjfAa6pm95QMibMHlVlfqspg8FewRBvXuuCWLKrCtxfQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p><span style=\"font-size: 14px;font-family: Cambria;\"><br \/><\/span><\/p>\n<p><span style=\"font-family: Cambria;font-size: 14px;\">\u5982\u56fe\u4ecefile->open\u53ef\u4ee5\u9009\u62e9\u6253\u5f00\u672c\u5730\u5c0f\u5206\u5b50\u6587\u4ef6<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 20px;\"><em><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><strong><br \/><\/strong><\/span><\/em><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5342857142857143\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/14_q1Fkn8UpkDN7gncDGMnDuFea7IMTCg-3.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5ohicLSY1BHnmWE0zarbkm1a8Oq1Fkn8UpkDN7gncDGMnDuFea7IMTCg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u5982\u56fe\u70b9\u51fbSmall Molecules>Prepare or Filter Ligands>Prepare Ligands\uff0c\u53ef\u4ee5\u6253\u5f00\u53c2\u6570\u8bbe\u7f6e\u9762\u677f\uff1b\u8bbe\u7f6eInput Ligands \u53c2\u6570\u4e3a’\u6587\u4ef6\u540d:All’\uff0c\u5373\u8868\u793a\u5bf9\u6240\u6709\u7684\u5c0f\u5206\u5b50\u8fdb\u884c\u5904\u7406\uff0c\u5176\u4f59\u53c2\u6570\u4e00\u822c\u9ed8\u8ba4\uff0c\u968f\u540e\u70b9\u51fbRUN\u8fd0\u884c\u3002<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5371428571428571\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/15_Cib7I9icLtIoqic8KDgFTblia6rdGw-3.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5MibC3jaBQgibJe6eF4PTWz4AbshdFMCib7I9icLtIoqic8KDgFTblia6rdGw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u8fd0\u884c\u7ed3\u675f\u540e\uff0c\u6211\u4eec\u53ef\u4ee5\u5728\u5f39\u51fa\u7684\u7a97\u53e3\u70b9\u51fbreport\u6765\u67e5\u770b\u5904\u7406\u4fe1\u606f\uff0c\u70b9\u51fb\u53f3\u4fa7\u7684view result\u540e\u5c31\u4f1a\u5f39\u51fa\u5de6\u4fa7\u7684\u754c\u9762\u89c2\u5bdf\u5904\u7406\u7ed3\u679c\u3002<o:p><\/o:p><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5342857142857143\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/16_l73pyrTLR8hAFqUOI1FJovAG6ibeFQ-3.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5dZ0fn81Y09KYgmx3gaw4ZKh72l73pyrTLR8hAFqUOI1FJovAG6ibeFQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5371428571428571\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/17_6ZbJ4ibibu50roEzqIPNObiaL8iaHA-3.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5FqLLyv3OAhib9IDiaia8lDxk951ibkick6ZbJ4ibibu50roEzqIPNObiaL8iaHA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u5c0f\u4f19\u4f34\u4eec\u53ef\u80fd\u8fd8\u4e0d\u77e5\u9053\u8fd9\u4e00\u6b65\u64cd\u4f5c\u6709\u4ec0\u4e48\u4f5c\u7528\uff0c\u5c0f\u679c\u5728\u8fd9\u91cc\u7ed9\u5927\u5bb6\u89e3\u91ca\u4e00\u4e0b\uff1a\u901a\u8fc7”Prepare Ligands”\u529f\u80fd\uff0c\u53ef\u4ee5\u5bf9\u5c0f\u5206\u5b50\u8fdb\u884c\u4ee5\u4e0b\u64cd\u4f5c\uff1a<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u6e05\u6d01\u5316\u5408\u7269\u7ed3\u6784\uff1a\u4fee\u590d\u5c0f\u5206\u5b50\u4e2d\u7684\u7ed3\u6784\u95ee\u9898\uff0c\u5982\u4fee\u590d\u952e\u8fde\u63a5\u9519\u8bef\u3001\u586b\u8865\u7f3a\u5931\u539f\u5b50\u6216\u4fee\u6b63\u539f\u5b50\u7684\u5f62\u5f0f\u7535\u8377\u7b49\uff0c\u786e\u4fdd\u5206\u5b50\u7ed3\u6784\u7684\u6b63\u786e\u6027\u548c\u4e00\u81f4\u6027\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u6dfb\u52a0\u6c22\u539f\u5b50\uff1a\u4e3a\u4e86\u8fdb\u884c\u5206\u5b50\u529b\u573a\u8ba1\u7b97\u548c\u5176\u4ed6\u76f8\u5e94\u8ba1\u7b97\uff0c\u901a\u5e38\u9700\u8981\u5728\u5c0f\u5206\u5b50\u4e0a\u6dfb\u52a0\u9002\u5f53\u7684\u6c22\u539f\u5b50\u3002”Prepare Ligands”\u529f\u80fd\u53ef\u4ee5\u81ea\u52a8\u6dfb\u52a0\u6c22\u539f\u5b50\uff0c\u5e76\u8c03\u6574\u5176\u4f4d\u7f6e\uff0c\u4ee5\u4f7f\u5f97\u5206\u5b50\u80fd\u591f\u5728\u529b\u573a\u8ba1\u7b97\u4e2d\u5f97\u5230\u6b63\u786e\u7684\u63cf\u8ff0\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u79bb\u5b50\u5316\u5904\u7406\uff1a\u8be5\u529f\u80fd\u53ef\u4ee5\u5c06\u5c0f\u5206\u5b50\u7684\u79bb\u5b50\u72b6\u6001\u8fdb\u884c\u4fee\u6b63\uff0c\u5728\u6a21\u62df\u548c\u8ba1\u7b97\u8fc7\u7a0b\u4e2d\u8003\u8651\u6eb6\u5242\u548c\u79bb\u5b50\u7684\u6548\u5e94\u3002\u4f8b\u5982\uff0c\u53ef\u4ee5\u5bf9\u5c0f\u5206\u5b50\u8fdb\u884c\u8d28\u5b50\u5316\u6216\u53bb\u8d28\u5b50\u5316\u5904\u7406\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u80fd\u91cf\u6700\u5c0f\u5316\uff1a”Prepare Ligands”\u8fd8\u63d0\u4f9b\u4e86\u80fd\u91cf\u6700\u5c0f\u5316\u7684\u9009\u9879\uff0c\u4ee5\u8fdb\u4e00\u6b65\u4f18\u5316\u5c0f\u5206\u5b50\u7684\u6784\u8c61\u548c\u6027\u80fd\u3002\u901a\u8fc7\u80fd\u91cf\u6700\u5c0f\u5316\uff0c\u53ef\u4ee5\u5bfb\u627e\u5c0f\u5206\u5b50\u7684\u6700\u7a33\u5b9a\u6784\u8c61\uff0c\u8bc4\u4f30\u5176\u80fd\u91cf\u548c\u51e0\u4f55\u53c2\u6570\uff0c\u5e76\u4e3a\u540e\u7eed\u8ba1\u7b97\u63d0\u4f9b\u66f4\u53ef\u9760\u7684\u8d77\u70b9\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u6211\u4eec\u8fd8\u53ef\u4ee5\u901a\u8fc7Small Molecules|Minimize Ligands>Full Minimization\u6309\u94ae\u6267\u884c\u5c0f\u5206\u5b50\u7684\u5168\u80fd\u91cf\u6700\u5c0f\u5316\u8ba1\u7b97\uff0c\u8c03\u6574\u539f\u5b50\u7684\u4f4d\u7f6e\u548c\u952e\u957f\u3001\u89d2\u5ea6\u7b49\u53c2\u6570\uff0c\u5e2e\u52a9\u4f18\u5316\u5206\u5b50\u7684\u51e0\u4f55\u5f62\u72b6\u548c\u7a7a\u95f4\u6392\u5e03\uff0c\u5bfb\u627e\u5c0f\u5206\u5b50\u7684\u6700\u7a33\u5b9a\u6784\u8c61\u3002<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5342857142857143\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/18_G1Z4j0Jn0xTe98muaGzKU1JPCXlLmQ-3.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5EawdqibNDckJD5bCZwwkMoTCLG1Z4j0Jn0xTe98muaGzKU1JPCXlLmQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u4f9d\u7136\u662f\u8bbe\u7f6eInput Ligands \u53c2\u6570\u4e3a’\u6587\u4ef6\u540d:All’\uff0c\u5176\u4f59\u53c2\u6570\u9ed8\u8ba4\uff0c\u968f\u540e\u70b9\u51fbRUN\u8fd0\u884c\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u8fd0\u884c\u7ed3\u675f\u540e\uff0c\u6211\u4eec\u53ef\u4ee5\u4ece\u8f6f\u4ef6\u6700\u4e0b\u65b9\u7684jobs\u4e2d\u627e\u5230\u6211\u4eec\u8fdb\u884c\u8fc7\u7684\u64cd\u4f5c\uff0c\u70b9\u51fb\u5373\u53ef\u6253\u5f00\u5df2\u7ecf\u5b8c\u6210\u8fc7\u7684\u64cd\u4f5c\u7ed3\u679c\u5566\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5371428571428571\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/19_wV5DEqic2mEUMDicT9jqNPzticUlbg-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5zVy0EO8yrTjvUt8JlNtu9xJLkduwV5DEqic2mEUMDicT9jqNPzticUlbg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u5c0f\u4f19\u4f34\u4eec\u53ef\u4ee5\u70b9\u51fb\u53f3\u4fa7\u7a97\u53e3\u6700\u4e0b\u9762\u7684view results\u6765\u66f4\u76f4\u89c2\u5730\u89c2\u770b\u7ed3\u679c\uff0c\u968f\u540e\u5c31\u4f1a\u5f39\u51fa\u5de6\u4fa7\u7ed3\u679c\u7a97\u53e3\uff0c\u6211\u4eec\u4e5f\u53ef\u4ee5\u8fdb\u884c\u62d6\u52a8\u7b49\u64cd\u4f5c\u6765\u89c2\u5bdf\u7ed3\u679c\u3002<\/span><span style=\"mso-spacerun:'yes';font-family:Cambria;mso-bidi-font-family:'Times New Roman';font-size:12.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5357142857142857\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/20_ahlulMMicRdsnPMyCITuaicVCNU0AA-4.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyaPhVurqkEWmvKUnibibN3Q5K2aCEJEOT5kDDAdGpJicJYGN2EPahlulMMicRdsnPMyCITuaicVCNU0AA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"700\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><span style=\"font-size: 14px;\">\u5230\u8fd9\u91cc\u4e3a\u6b62\uff0c\u914d\u4f53\u8bbe\u8ba1\u7684\u6700\u4e3b\u8981\u6d41\u7a0b\u5c31\u5df2\u7ecf\u5b8c\u6210\u5566\uff0c\u600e\u4e48\u6837\uff0c\u662f\u4e0d\u662f\u975e\u5e38\u7b80\u5355\u5462\uff1f\u7ec6\u5fc3\u7684\u5c0f\u4f19\u4f34\u53ef\u80fd\u5df2\u7ecf\u6ce8\u610f\u5230\uff0c\u5f53\u6211\u4eec\u628a\u9f20\u6807\u653e\u5230<\/span>discovery studio\u7684\u5927\u591a\u6570\u6309\u94ae\u4e0a\u65f6\uff0c\u4f1a\u51fa\u73b0help\u6309\u94ae\uff0c\u5728\u4f7f\u7528\u8fc7\u7a0b\u4e2d\u5c0f\u4f19\u4f34\u4eec\u5982\u679c\u6709\u4ec0\u4e48\u7591\u95ee\u4e00\u5b9a\u8981\u591a\u67e5\u770bhelp\u54e6\uff0c\u53ea\u6709\u6df1\u5165\u4e86\u89e3\u539f\u7406\u548c\u5177\u4f53\u64cd\u4f5c\u6b65\u9aa4\u624d\u80fd\u5b8c\u6210\u5408\u683c\u7684\u836f\u7269\u8bbe\u8ba1\u3002<o:p><\/o:p><\/span><\/p>\n<p style=\"text-align: left;\"><span style=\"text-align: left;letter-spacing: 0.034em;\"><\/span><span style=\"text-align: left;letter-spacing: 0.578px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u5c0f\u4f19\u4f34\u6709\u6ca1\u6709\u5fc3\u52a8\u5462\uff0c\u5feb\u53bb\u8bd5\u8bd5\u5427\uff0c\u4e0d\u8981\u5fd8\u8bb0\u591a\u591a\u7406\u89e3\u4ee3\u7801\u7684\u610f\u4e49\uff0c\u8fd9\u6837\u624d\u80fd\u5957\u7528\u81ea\u5df1\u6570\u636e\u8fdb\u884c\u5c55\u793a\u3002<\/span><strong style=\"text-align: left;color: rgb(121, 123, 170);font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;outline: 0px;font-size: 15px;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);\">\u4ee5\u4e0b\u63a8\u8350\u7684\u662f\u4e00\u4e2a\u591a\u529f\u80fd\u7684\u751f\u4fe1\u5e73\u53f0\uff0c\u70b9\u51fb\u539f\u6587\u7acb\u523b\u4e86\u89e3~<\/strong><br \/><\/p>\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><\/span><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: 0px;letter-spacing: 0.578px;white-space: normal;\">\n<section style=\"font-size: 16px;\">\n<section powered-by=\"xiumi.us\" style=\"margin: 10px;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\">\n<section style=\"padding-right: 10px;padding-left: 10px;display: 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textvalue=\"1.\u642d\u5efa\u751f\u4fe1\u5206\u6790\u6d41\u6c34\u7ebf\uff0c\u5982\u5de5\u5382\u4e00\u683724\u5c0f\u65f6\u8fd0\u8f6cSnakemake\u2014\u2014\u8fdb\u9636\u547d\u4ee4\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">1.\u642d\u5efa\u751f\u4fe1\u5206\u6790\u6d41\u6c34\u7ebf\uff0c\u5982\u5de5\u5382\u4e00\u683724\u5c0f\u65f6\u8fd0\u8f6cSnakemake\u2014\u2014\u8fdb\u9636\u547d\u4ee4<\/a><br \/><\/section>\n<section style=\"letter-spacing: 0.578px;line-height: 1.75em;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247491705&idx=1&sn=9ff9b6da28b3a256a99c6697d589be66&chksm=cf7f70bcf808f9aafd1019a0bba3dd3a55e2867dbb9a09203f13c2683adf867094637c405ed1&scene=21#wechat_redirect\" textvalue=\"2.\u6bd4blast\u8fd8\u4f18\u79c0\u7684\u5e8f\u5217\u6bd4\u5bf9\u5de5\u5177\uff1fHMMER\u6765\u4e86\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" 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