{"id":54003,"date":"2024-06-16T13:32:33","date_gmt":"2024-06-16T05:32:33","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=54003"},"modified":"2024-06-16T13:32:33","modified_gmt":"2024-06-16T05:32:33","slug":"%e5%b0%8f%e6%9e%9c%e4%ba%94%e5%88%86%e9%92%9f%e6%95%99%e4%bc%9a%e4%bd%a0%e4%bd%bf%e7%94%a8stutility%e8%af%ad%e8%a8%80%e5%8c%85%e5%88%86%e6%9e%90%e7%a9%ba%e9%97%b4%e8%bd%ac%e5%bd%95%e7%bb%84%e6%95%b0","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=54003","title":{"rendered":"\u5c0f\u679c\u4e94\u5206\u949f\u6559\u4f1a\u4f60\u4f7f\u7528STUtility\u8bed\u8a00\u5305\u5206\u6790\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u6570\u636e"},"content":{"rendered":"


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0.034em;\">STUtility\u5305\u63d0\u4f9b\u4e86\u4e00\u7cfb\u5217\u805a\u7c7b\u7b97\u6cd5\u548c\u65b9\u6cd5\uff0c\u4ee5\u81ea\u52a8\u8bc6\u522b\u51fa\u5177\u6709\u76f8\u4f3c\u8868\u8fbe\u6a21\u5f0f\u7684\u57fa\u56e0\u7fa4\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u8fd9\u6709\u52a9\u4e8e\u7814\u7a76\u4eba\u5458\u4ece\u6570\u636e\u4e2d\u6316\u6398\u51fa\u7ec6\u80de\u7684\u6f5c\u5728\u5206\u7c7b\uff0c\u5e76\u53d1\u73b0\u9690\u85cf\u5728\u6570\u636e\u80cc\u540e\u7684\u751f\u7269\u5b66\u610f\u4e49\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u901a\u8fc7\u5bf9\u7ec6\u80de\u7fa4\u843d\u7684\u5212\u5206\uff0c\u79d1\u5b66\u5bb6\u4eec\u53ef\u4ee5\u66f4\u5168\u9762\u5730\u4e86\u89e3\u7ec4\u7ec7\u7684\u7ed3\u6784\uff0c\u63ed\u793a\u51fa\u4e0d\u540c\u7ec6\u80de\u7c7b\u578b\u5728\u7a7a\u95f4\u4e0a\u7684\u5206\u5e03\uff0c\u8fdb\u800c\u7814\u7a76\u7ec6\u80de\u7684\u529f\u80fd\u548c\u76f8\u4e92\u4f5c\u7528\u3002<\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u7ec6\u80de\u7c7b\u578b\u7684\u8bc6\u522b\u662f\u7a7a\u95f4\u805a\u7c7b\u7684\u4e00\u4e2a\u91cd\u8981\u5e94\u7528\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u901a\u8fc7\u5c06\u805a\u7c7b\u7ed3\u679c\u4e0e\u5df2\u77e5\u7684\u7ec6\u80de\u6807\u8bb0\u8fdb\u884c\u5bf9\u6bd4\uff0c\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u5c06\u6bcf\u4e2a\u7ec6\u80de\u7fa4\u843d\u4e0e\u7279\u5b9a\u7684\u7ec6\u80de\u7c7b\u578b\u5173\u8054\u8d77\u6765\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u8fd9\u4f7f\u5f97\u6211\u4eec\u80fd\u591f\u5728\u7ec4\u7ec7\u5185\u51c6\u786e\u5730\u8bc6\u522b\u4e0d\u540c\u7684\u7ec6\u80de\u7c7b\u578b\uff0c\u4ece\u800c\u6df1\u5165\u4e86\u89e3\u7ec6\u80de\u5728\u7ec4\u7ec7\u7ed3\u6784\u548c\u751f\u7269\u5b66\u529f\u80fd\u4e2d\u7684\u4f5c\u7528\u3002<\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">IV.\u57fa\u56e0\u8868\u8fbe\u6a21\u5f0f\u5206\u6790\uff1a<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u5229\u7528STUtility\u5305\u63a2\u7d22\u4e0d\u540c\u533a\u57df\u5185\u57fa\u56e0\u7684\u8868\u8fbe\u6a21\u5f0f\uff0c\u4ece\u800c\u8bc6\u522b\u51fa\u5728\u7279\u5b9a\u751f\u7269\u5b66\u8fc7\u7a0b\u4e2d\u53ef\u80fd\u8d77\u5173\u952e\u4f5c\u7528\u7684\u57fa\u56e0\u3002<\/span><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u57fa\u56e0\u8868\u8fbe\u6a21\u5f0f\u5206\u6790\u662fSTUtility\u5305\u7684\u4e00\u4e2a\u6838\u5fc3\u529f\u80fd\uff0c\u5b83\u5141\u8bb8\u7814\u7a76\u4eba\u5458\u6df1\u5165\u7814\u7a76\u4e0d\u540c\u533a\u57df\u5185\u57fa\u56e0\u7684\u8868\u8fbe\u6c34\u5e73\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u901a\u8fc7\u5206\u6790\u57fa\u56e0\u5728\u7ec4\u7ec7\u7684\u7a7a\u95f4\u5206\u5e03\uff0c\u79d1\u5b66\u5bb6\u4eec\u53ef\u4ee5\u8bc6\u522b\u51fa\u5728\u7279\u5b9a\u533a\u57df\u6216\u7ec6\u80de\u7c7b\u578b\u4e2d\u8868\u8fbe\u663e\u8457\u589e\u52a0\u6216\u51cf\u5c11\u7684\u57fa\u56e0\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u8fd9\u4e9b\u57fa\u56e0\u53ef\u80fd\u5728\u7279\u5b9a\u7684\u751f\u7269\u5b66\u8fc7\u7a0b\u4e2d\u8d77\u7740\u91cd\u8981\u4f5c\u7528\uff0c\u5982\u53d1\u80b2\u3001\u514d\u75ab\u53cd\u5e94\u6216\u75be\u75c5\u53d1\u5c55\u7b49\u3002<\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u6839\u636e\u611f\u5174\u8da3\u7684\u7ec6\u80de\u533a\u57df\u6216\u7ec4\u7ec7\u533a\u57df\uff0c\u5206\u6790\u57fa\u56e0\u5728\u8fd9\u4e9b\u533a\u57df\u4e2d\u7684\u8868\u8fbe\u6c34\u5e73\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u901a\u8fc7\u6bd4\u8f83\u4e0d\u540c\u533a\u57df\u4e4b\u95f4\u7684\u8868\u8fbe\u5dee\u5f02\uff0c\u79d1\u5b66\u5bb6\u4eec\u53ef\u4ee5\u8bc6\u522b\u51fa\u5728\u7279\u5b9a\u6761\u4ef6\u4e0b\u663e\u8457\u8868\u8fbe\u7684\u57fa\u56e0\u96c6\u5408\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u8fd9\u6709\u52a9\u4e8e\u6211\u4eec\u53d1\u73b0\u6f5c\u5728\u7684\u751f\u7269\u5b66\u5019\u9009\u57fa\u56e0\uff0c\u8fdb\u4e00\u6b65\u7814\u7a76\u5b83\u4eec\u5728\u751f\u7269\u4f53\u5185\u7684\u529f\u80fd\u548c\u8c03\u63a7\u673a\u5236\u3002<\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u57fa\u56e0\u8868\u8fbe\u6a21\u5f0f\u5206\u6790\u8fd8\u53ef\u4ee5\u5e2e\u52a9\u7814\u7a76\u4eba\u5458\u4e86\u89e3\u4e0d\u540c\u533a\u57df\u4e4b\u95f4\u7684\u76f8\u4f3c\u6027\u548c\u5dee\u5f02\u6027\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u901a\u8fc7\u805a\u7c7b\u5206\u6790\u548c\u53ef\u89c6\u5316\uff0cSTUtility\u5305\u53ef\u4ee5\u5e2e\u52a9\u7814\u7a76\u4eba\u5458\u8bc6\u522b\u51fa\u5728\u57fa\u56e0\u8868\u8fbe\u6a21\u5f0f\u4e0a\u5177\u6709\u76f8\u4f3c\u6027\u7684\u533a\u57df\u7fa4\u843d\uff0c\u4ece\u800c\u63ed\u793a\u7ec4\u7ec7\u5185\u4e0d\u540c\u533a\u57df\u4e4b\u95f4\u7684\u8054\u7cfb\u3002<\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">V.\u53ef\u89c6\u5316\u5de5\u5177\uff1a<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">STUtility\u5305\u63d0\u4f9b\u4e86\u4e30\u5bcc\u7684\u53ef\u89c6\u5316\u9009\u9879\uff0c\u5e2e\u52a9\u7814\u7a76\u4eba\u5458\u5c06\u5206\u6790\u7ed3\u679c\u4ee5\u76f4\u89c2\u7684\u65b9\u5f0f\u5448\u73b0\uff0c\u4ece\u800c\u66f4\u597d\u5730\u4f20\u8fbe\u7814\u7a76\u6210\u679c\u3002<\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">STUtility\u5305\u7684\u53ef\u89c6\u5316\u529f\u80fd\u6db5\u76d6\u4e86\u5404\u4e2a\u5206\u6790\u6b65\u9aa4\u548c\u7ed3\u679c\uff0c\u4ece\u6570\u636e\u9884\u5904\u7406\u5230\u7a7a\u95f4\u8868\u8fbe\u56fe\u8c31\u7684\u6784\u5efa\uff0c\u518d\u5230\u7ec6\u80de\u7c7b\u578b\u8bc6\u522b\u548c\u57fa\u56e0\u8868\u8fbe\u6a21\u5f0f\u5206\u6790\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u8fd9\u4e9b\u53ef\u89c6\u5316\u9009\u9879\u4f7f\u5f97\u7814\u7a76\u4eba\u5458\u80fd\u591f\u4ee5\u56fe\u50cf\u7684\u5f62\u5f0f\u5c55\u793a\u4ed6\u4eec\u7684\u7814\u7a76\u53d1\u73b0\uff0c\u4f7f\u5f97\u590d\u6742\u7684\u6570\u636e\u53d8\u5f97\u6613\u4e8e\u7406\u89e3\u3002<\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u5728\u6570\u636e\u9884\u5904\u7406\u9636\u6bb5\uff0cSTUtility\u5305\u53ef\u4ee5\u901a\u8fc7\u7ed8\u5236\u6570\u636e\u7684\u8d28\u91cf\u8bc4\u4f30\u56fe\u6765\u5c55\u793a\u6570\u636e\u7684\u6e05\u6d01\u7a0b\u5ea6\u548c\u53ef\u9760\u6027\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u8fd9\u6709\u52a9\u4e8e\u7814\u7a76\u4eba\u5458\u4e86\u89e3\u54ea\u4e9b\u6837\u672c\u53ef\u80fd\u5b58\u5728\u5f02\u5e38\uff0c\u4ece\u800c\u6307\u5bfc\u540e\u7eed\u7684\u6570\u636e\u5904\u7406\u548c\u5206\u6790\u3002<\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u5728\u7a7a\u95f4\u8868\u8fbe\u56fe\u8c31\u6784\u5efa\u9636\u6bb5\uff0cSTUtility\u5305\u7684\u53ef\u89c6\u5316\u5de5\u5177\u53ef\u4ee5\u5c06\u57fa\u56e0\u8868\u8fbe\u6570\u636e\u6620\u5c04\u5230\u7ec4\u7ec7\u7ed3\u6784\u4e0a\uff0c\u751f\u6210\u751f\u52a8\u7684\u56fe\u50cf\uff0c\u663e\u793a\u57fa\u56e0\u5728\u7ec4\u7ec7\u4e2d\u7684\u7a7a\u95f4\u5206\u5e03\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u8fd9\u4e9b\u56fe\u8c31\u53ef\u4ee5\u5e2e\u52a9\u7814\u7a76\u4eba\u5458\u66f4\u76f4\u89c2\u5730\u89c2\u5bdf\u57fa\u56e0\u7684\u8868\u8fbe\u6a21\u5f0f\uff0c\u63ed\u793a\u4e0d\u540c\u533a\u57df\u548c\u7ec6\u80de\u7c7b\u578b\u4e4b\u95f4\u7684\u5dee\u5f02\u3002<\/span><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u5728\u7ec6\u80de\u7c7b\u578b\u8bc6\u522b\u548c\u57fa\u56e0\u8868\u8fbe\u6a21\u5f0f\u5206\u6790\u9636\u6bb5\uff0cSTUtility\u5305\u53ef\u4ee5\u901a\u8fc7\u7ed8\u5236\u70ed\u56fe\u3001\u6563\u70b9\u56fe\u3001\u805a\u7c7b\u56fe\u7b49\u591a\u79cd\u56fe\u8868\uff0c\u5c55\u793a\u4e0d\u540c\u7ec6\u80de\u7fa4\u843d\u3001\u57fa\u56e0\u96c6\u5408\u4ee5\u53ca\u5176\u8868\u8fbe\u6a21\u5f0f\u4e4b\u95f4\u7684\u5173\u7cfb\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u8fd9\u4e9b\u53ef\u89c6\u5316\u5de5\u5177\u4e0d\u4ec5\u5e2e\u52a9\u7814\u7a76\u4eba\u5458\u8bc6\u522b\u51fa\u6f5c\u5728\u7684\u7ec6\u80de\u7c7b\u578b\uff0c\u8fd8\u80fd\u591f\u5e2e\u52a9\u4ed6\u4eec\u53d1\u73b0\u5728\u7279\u5b9a\u751f\u7269\u5b66\u8fc7\u7a0b\u4e2d\u53ef\u80fd\u8d77\u5173\u952e\u4f5c\u7528\u7684\u57fa\u56e0\u3002<\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-imgfileid=\"100012445\" data-ratio=\"0.38981481481481484\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-11-29_\u5c0f\u679c\u4e94\u5206\u949f\u6559\u4f1a\u4f60\u4f7f\u7528STUtility\u8bed\u8a00\u5305\u5206\u6790\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u6570\u636e\/2_IWicymEetCc6Enf2BkUE4Yz1Ya5e5w.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyuYsqlJnQUJvnS2iciaDibtfbdV0VmHlriaSjYwjFPLp1BLjokHIWicymEetCc6Enf2BkUE4Yz1Ya5e5w\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"letter-spacing: 0.578px;text-wrap: wrap;text-align: center;\" \/><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u793a\u4f8b\uff1a<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\"><\/span><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"shell\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#<\/span>\u5b89\u88c5\u5e76\u52a0\u8f7d\u8bed\u8a00\u5305<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">><\/span> install.packages(<span class=\"code-snippet__string\">\"STUtility\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">><\/span> library(STUtility)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#<\/span> \u5047\u8bbegene_expression\u662f\u57fa\u56e0\u8868\u8fbe\u6570\u636e\uff0clocations\u662f\u7ec4\u7ec7\u7ed3\u6784\u4fe1\u606f<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet_outer\">#<\/span> \u8fdb\u884c\u6570\u636e\u9884\u5904\u7406<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">><\/span> cleaned_data <- preprocess_data(gene_expression, locations)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#<\/span> \u8fdb\u884c\u7ec6\u80de\u7c7b\u578b\u8bc6\u522b\u548c\u805a\u7c7b<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">><\/span> cell_clusters <- identify_cell_clusters(cleaned_data)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#<\/span> \u5c06\u57fa\u56e0\u8868\u8fbe\u6570\u636e\u6620\u5c04\u5230\u7ec4\u7ec7\u7ed3\u6784\u4e0a\uff0c\u751f\u6210\u7a7a\u95f4\u8868\u8fbe\u56fe\u8c31<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet_outer\">><\/span> expression_map <- generate_expression_map(cleaned_data, cell_clusters)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#<\/span> \u53ef\u89c6\u5316\u7a7a\u95f4\u8868\u8fbe\u56fe\u8c31<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet_outer\">><\/span> plot_expression_map(expression_map)<\/span><\/code><\/pre>\n<\/section>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100012379\" data-ratio=\"1\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-11-29_\u5c0f\u679c\u4e94\u5206\u949f\u6559\u4f1a\u4f60\u4f7f\u7528STUtility\u8bed\u8a00\u5305\u5206\u6790\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u6570\u636e\/3_MeTNE1z4fiaOoUo98Y4FbrEScPPdkA.jpg\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAxPqeNQsFjm2HibIuSld9Nh9LeeQ5Cq6UHWOx1egDF0eiaVibTicMeTNE1z4fiaOoUo98Y4FbrEScPPdkA\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"791\" height=\"553.739990234375\" width=\"553.739990234375\" \/><\/p>\n<p><span style=\"font-size: 15px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">          <\/span><o:p><span style=\"font-size: 15px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"> <\/span><\/o:p><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100012380\" data-ratio=\"0.6\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-11-29_\u5c0f\u679c\u4e94\u5206\u949f\u6559\u4f1a\u4f60\u4f7f\u7528STUtility\u8bed\u8a00\u5305\u5206\u6790\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u6570\u636e\/4_rKrQv74nVtKchIQh3nqz2sc0RvLg0A.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAxPqeNQsFjm2HibIuSld9Nh9N8kRqbRRR3xiaibNbic2YMiaKPN8rKrQv74nVtKchIQh3nqz2sc0RvLg0A\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1000\" height=\"331.80999755859375\" style=\"font-size: var(--articleFontsize);letter-spacing: 0.034em;\" width=\"553.010009765625\" \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"shell\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#<\/span> \u7ed8\u5236\u7ec6\u80de\u7c7b\u578b\u4e4b\u95f4\u7684\u57fa\u56e0\u8868\u8fbe\u70ed\u56fe <\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">><\/span> heatmap_plot <- plot_cell_type_heatmap(cleaned_data, cell_clusters)<\/span><\/code><\/pre>\n<\/section>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100012381\" data-ratio=\"1.9134078212290502\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-11-29_\u5c0f\u679c\u4e94\u5206\u949f\u6559\u4f1a\u4f60\u4f7f\u7528STUtility\u8bed\u8a00\u5305\u5206\u6790\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u6570\u636e\/5_CgicvC21lwcjw0bvst0kUTa9JLme2w.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAxPqeNQsFjm2HibIuSld9Nh90icOvckU7nfmcAicxaDDBjmRsDWCgicvC21lwcjw0bvst0kUTa9JLme2w\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"358\" height=\"544.280029296875\" width=\"284.3999938964844\" \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"shell\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#<\/span> \u9009\u62e9\u51e0\u4e2a\u611f\u5174\u8da3\u7684\u57fa\u56e0\u8fdb\u884c\u5206\u6790<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet_outer\">><\/span> target_genes <- c(<span class=\"code-snippet__string\">\"Gene1\"<\/span>, <span class=\"code-snippet__string\">\"Gene2\"<\/span>, <span class=\"code-snippet__string\">\"Gene3\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#<\/span> \u7ed8\u5236\u57fa\u56e0\u5728\u4e0d\u540c\u7ec6\u80de\u7c7b\u578b\u4e2d\u7684\u6563\u70b9\u56fe<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">><\/span> scatter_plots <- plot_gene_expression_scatter(cleaned_data, cell_clusters, target_genes)<\/span><\/code><\/pre>\n<\/section>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100012382\" data-ratio=\"0.6094117647058823\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-11-29_\u5c0f\u679c\u4e94\u5206\u949f\u6559\u4f1a\u4f60\u4f7f\u7528STUtility\u8bed\u8a00\u5305\u5206\u6790\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u6570\u636e\/6_bykxjYVGRJgw2kKapGicJQwNZmAghA.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAxPqeNQsFjm2HibIuSld9Nh9TVUZIv5L7zn1RyTSXZfEYQtbWibykxjYVGRJgw2kKapGicJQwNZmAghA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"850\" height=\"337.2099914550781\" width=\"553.3400268554688\" \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u901a\u8fc7\u4e0a\u8ff0\u6b65\u9aa4\uff0c\u6211\u4eec\u53ef\u4ee5\u5728R\u4e2d\u4f7f\u7528STUtility\u5305\u5bf9\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u6570\u636e\u8fdb\u884c\u5206\u6790\uff0c\u5e76\u5f97\u5230\u4e00\u7cfb\u5217\u53ef\u89c6\u5316\u56fe\u8868\u6765\u5c55\u793a\u7ec6\u80de\u7c7b\u578b\u8bc6\u522b\u3001\u7a7a\u95f4\u8868\u8fbe\u56fe\u8c31\u6784\u5efa\u4ee5\u53ca\u57fa\u56e0\u8868\u8fbe\u6a21\u5f0f\u5206\u6790\u7684\u7ed3\u679c\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u8fd9\u4e9b\u56fe\u8868\u5c06\u5e2e\u52a9\u6211\u4eec\u66f4\u597d\u5730\u7406\u89e3\u6570\u636e\uff0c\u63ed\u793a\u751f\u7269\u5b66\u4fe1\u606f\uff0c\u5e76\u4e3a\u7814\u7a76\u6210\u679c\u7684\u4f20\u8fbe\u63d0\u4f9b\u6709\u529b\u652f\u6301\u3002<\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u5728\u751f\u7269\u5b66\u7814\u7a76\u4e2d\uff0cSTUtility\u5305\u7684\u5e94\u7528\u5177\u6709\u5e7f\u6cdb\u7684\u6f5c\u529b\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u4f8b\u5982\uff0c\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u5229\u7528\u8be5\u5305\u6765\u7814\u7a76\u7ec4\u7ec7\u4e2d\u4e0d\u540c\u533a\u57df\u7684\u7ec6\u80de\u7c7b\u578b\u5206\u5e03\uff0c\u4ece\u800c\u6df1\u5165\u4e86\u89e3\u7ec4\u7ec7\u7684\u7ed3\u6784\u548c\u529f\u80fd\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u6b64\u5916\uff0cSTUtility\u5305\u8fd8\u53ef\u4ee5\u5e2e\u52a9\u79d1\u5b66\u5bb6\u4eec\u5728\u75be\u75c5\u7814\u7a76\u4e2d\u63ed\u793a\u75c5\u7406\u8fc7\u7a0b\u4e2d\u57fa\u56e0\u8868\u8fbe\u7684\u7a7a\u95f4\u53d8\u5316\uff0c\u4ece\u800c\u6709\u52a9\u4e8e\u53d1\u73b0\u6f5c\u5728\u7684\u6cbb\u7597\u9776\u70b9\u3002<\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u4ee5\u4e0a\u5c31\u662f\u5bf9R\u8bed\u8a00\u5305STUtility\u7684\u7b80\u5355\u4ecb\u7ecd\u5566\uff0cSTUtility\u662f\u4e00\u4e2a\u4e13\u95e8\u9488\u5bf9\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u6570\u636e\u5206\u6790\u800c\u8bbe\u8ba1\u7684R\u8bed\u8a00\u5305\uff0c\u4e3a\u751f\u7269\u5b66\u5bb6\u4eec\u63d0\u4f9b\u4e86\u5f3a\u5927\u7684\u5de5\u5177\u548c\u529f\u80fd\uff0c\u5e2e\u52a9\u4ed6\u4eec\u66f4\u597d\u5730\u7406\u89e3\u57fa\u56e0\u5728\u7ec4\u7ec7\u548c\u7ec6\u80de\u6c34\u5e73\u4e0a\u7684\u7a7a\u95f4\u8868\u8fbe\u6a21\u5f0f\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u8fd9\u79cd\u5de5\u5177\u7684\u5e94\u7528\u6709\u52a9\u4e8e\u63a8\u52a8\u751f\u7269\u5b66\u7814\u7a76\u7684\u8fdb\u5c55\uff0c\u4e3a\u6211\u4eec\u63ed\u793a\u751f\u547d\u7684\u5965\u79d8\u63d0\u4f9b\u66f4\u6df1\u5165\u7684\u89c1\u89e3\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">\u65e0\u8bba\u662f\u63a2\u7d22\u7ec4\u7ec7\u7684\u7ed3\u6784\u4e0e\u529f\u80fd\uff0c\u8fd8\u662f\u7814\u7a76\u75be\u75c5\u7684\u53d1\u75c5\u673a\u5236\uff0cSTUtility\u90fd\u5c06\u6210\u4e3a\u751f\u7269\u5b66\u5bb6\u4eec\u4e0d\u53ef\u6216\u7f3a\u7684\u4f19\u4f34\u3002<\/span><\/p>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: 0px;letter-spacing: 0.578px;text-wrap: wrap;outline: 0px;font-family: system-ui, -apple-system, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;background-color: rgb(255, 255, 255);text-align: left;\">\n<section style=\"outline: 0px;font-size: 16px;\">\n<section powered-by=\"xiumi.us\" style=\"margin: 10px;outline: 0px;justify-content: flex-start;display: flex;flex-flow: row;\">\n<section style=\"padding-right: 10px;padding-left: 10px;outline: 0px;display: 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0px;\">\u5f80\u671f\u63a8\u8350<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;text-align: justify;\">\n<section style=\"outline: 0px;letter-spacing: 0.578px;line-height: 1.75em;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247491794&idx=1&sn=2b7a4de95169c79202e44813885a8250&chksm=cf7f7017f808f9015689839fe4057fd418bf7b20eb1dfb5a28cd92e56a41b5605e62bfbc16fb&scene=21#wechat_redirect\" textvalue=\"1.\u642d\u5efa\u751f\u4fe1\u5206\u6790\u6d41\u6c34\u7ebf\uff0c\u5982\u5de5\u5382\u4e00\u683724\u5c0f\u65f6\u8fd0\u8f6cSnakemake\u2014\u2014\u8fdb\u9636\u547d\u4ee4\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"color: var(--weui-LINK);outline: 0px;cursor: pointer;font-size: 14px;\" rel=\"noopener\">1.\u642d\u5efa\u751f\u4fe1\u5206\u6790\u6d41\u6c34\u7ebf\uff0c\u5982\u5de5\u5382\u4e00\u683724\u5c0f\u65f6\u8fd0\u8f6cSnakemake\u2014\u2014\u8fdb\u9636\u547d\u4ee4<\/a><br style=\"outline: 0px;\" \/><\/section>\n<section style=\"outline: 0px;letter-spacing: 0.578px;line-height: 1.75em;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247491705&idx=1&sn=9ff9b6da28b3a256a99c6697d589be66&chksm=cf7f70bcf808f9aafd1019a0bba3dd3a55e2867dbb9a09203f13c2683adf867094637c405ed1&scene=21#wechat_redirect\" textvalue=\"2.\u6bd4blast\u8fd8\u4f18\u79c0\u7684\u5e8f\u5217\u6bd4\u5bf9\u5de5\u5177\uff1fHMMER\u6765\u4e86\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"color: var(--weui-LINK);outline: 0px;cursor: pointer;font-size: 14px;\" rel=\"noopener\">2.\u6bd4blast\u8fd8\u4f18\u79c0\u7684\u5e8f\u5217\u6bd4\u5bf9\u5de5\u5177\uff1fHMMER\u6765\u4e86<\/a><\/section>\n<section style=\"outline: 0px;letter-spacing: 0.578px;line-height: 1.75em;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247491909&idx=1&sn=902e34bcf53e605fba2b457ec6a33e36&chksm=cf7f7180f808f8961542f458a49da14e85d8831449fb65fbf2623d55affc564686a5422f56fd&scene=21#wechat_redirect\" textvalue=\"3.\u5bf9\u5355\u7ec6\u80de\u5206\u6790\u6beb\u65e0\u5934\u7eea\uff1f\u8ba9popsicleR\u9886\u4f60\u5165\u95e8\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"color: var(--weui-LINK);outline: 0px;cursor: pointer;font-size: 14px;\" rel=\"noopener\">3.\u5bf9\u5355\u7ec6\u80de\u5206\u6790\u6beb\u65e0\u5934\u7eea\uff1f\u8ba9popsicleR\u9886\u4f60\u5165\u95e8<\/a><\/section>\n<section style=\"outline: 0px;letter-spacing: 0.578px;line-height: 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