{"id":54386,"date":"2024-06-16T14:11:02","date_gmt":"2024-06-16T06:11:02","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=54386"},"modified":"2024-06-16T14:11:02","modified_gmt":"2024-06-16T06:11:02","slug":"%e8%a2%ab%e5%a4%b8%e7%88%86%e7%9a%84%e6%9c%ba%e5%99%a8%e5%ad%a6%e4%b9%a0%e5%9c%a8%e8%bf%99%e9%87%8c%ef%bc%81%e5%8d%97%e4%b8%ad%e5%8c%bb%e5%88%98%e5%8a%b2%e6%9d%be6%e5%88%86%e6%96%b0%e4%bd%9c%ef%bc%8c","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=54386","title":{"rendered":"\u88ab\u5938\u7206\u7684\u673a\u5668\u5b66\u4e60\u5728\u8fd9\u91cc\uff01\u5357\u4e2d\u533b\u5218\u52b2\u677e6\u5206+\u65b0\u4f5c\uff0c10\u79cd\u673a\u5668\u5b66\u4e60\u7684101\u79cd\u7ec4\u5408+\u591a\u7ec4\u5b66\u9274\u5b9a\u514d\u75ab\u539f\u6027\u7ec6\u80de\u6b7b\u4ea1\uff0c0\u5b9e\u9a8c\u521b\u65b0\u601d\u8defMAX\uff01"},"content":{"rendered":"


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150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\">ccRCC<\/span><span style=\"letter-spacing: 1px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u8fdb\u884c\u4e86\u5168\u9762\u7684<\/span><span style=\"letter-spacing: 1px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 255);font-weight: bold;\">\u591a\u7ec4\u5b66\u5206\u6790<\/span><span style=\"letter-spacing: 1px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\uff0c\u5305\u62ec\u57fa\u56e0\u7ec4\u3001\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u548c\u6279\u91cf\u8f6c\u5f55\u7ec4\uff0c\u63ed\u793a\u4e86\u8be5\u7279\u5f81\u5728\u591a\u4e2a\u7ec4\u5b66\u6c34\u5e73\u4e0a\u7684\u5206\u5b50\u57fa\u7840\u548c\u6f5c\u5728\u673a\u5236\uff0c\u8bc1\u5b9e\u4e86\u5171\u8bc6\u514d\u75ab\u539f\u6027\u7ec6\u80de\u6b7b\u4ea1\u76f8\u5173\u7279\u5f81\uff08ICDRS\uff09\u4e0eccRCC\u7684\u53d1\u5c55\u548c\u9884\u540e\u7684\u5bc6\u5207\u5173\u8054\u3002<\/span><\/span><\/section>\n<section style=\"margin-left: 0pt;text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"letter-spacing: 1px;font-size: 16px;\"><span style=\"letter-spacing: 1px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\">3\uff0c<\/span><span style=\"letter-spacing: 1px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u672c\u7814\u7a76\u91c7\u7528\u4e86\u4e00\u79cd\u65b0\u7684<\/span><span style=\"letter-spacing: 1px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 255);font-weight: bold;\">\u751f\u7269\u4fe1\u606f\u5b66\u65b9\u6cd5<\/span><span style=\"letter-spacing: 1px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\uff0c\u8be5\u65b9\u6cd5\u7ed3\u5408\u4e86<\/span><span style=\"letter-spacing: 1px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(0, 0, 255);font-weight: bold;\">AddModuleScore\uff0cssGSEA<\/span><span style=\"letter-spacing: 1px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u548c<\/span><span style=\"letter-spacing: 1px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(0, 0, 255);font-weight: bold;\">WGCNA\u7b97\u6cd5<\/span><span style=\"letter-spacing: 1px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\uff0c\u4ee5\u5728\u5355\u7ec6\u80de\u548c\u6279\u91cf\u8f6c\u5f55\u7ec4\u4e0a\u9274\u5b9a\u514d\u75ab\u539f\u6027\u7ec6\u80de\u6b7b\u4ea1 \uff08ICD\uff09\u76f8\u5173\u57fa\u56e0\uff0c\u4e3aICD\u80cc\u666f\u4e0b\u7684ccRCC\u63d0\u4f9b\u6f5c\u5728\u7684\u6cbb\u7597\u9776\u70b9\u3002<\/span><span style=\"letter-spacing: 1px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;background: rgb(255, 255, 0);\">\u601d\u8def\u4e25\u8c28\uff0c\u65b9\u6cd5\u6613\u590d\u5236\uff0c\u60f3\u8981\u53d1\u8868\u9ad8\u5206SCI\u7684\u5c0f\u4f19\u4f34\u4eec\u4e5f\u53ef\u4ee5\u501f\u9274\u4e00\u4e0b\u672c\u6587\u7684\u7814\u7a76\u601d\u8def\u54e6~<\/span><span style=\"letter-spacing: 1px;font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(255, 0, 0);font-weight: bold;background: rgb(255, 255, 0);\">(ps\uff1a\u4e5f\u60f3\u8bd5\u8bd5\u673a\u5668\u5b66\u4e60\u5374\u6ca1\u6709\u601d\u8def\u7684\u5c0f\u4f19\u4f34\u53ef\u4ee5\u6765\u626b\u7801\u627e\u5c0f\u9014\u5662\uff01)\u3002<\/span>    <\/span><\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-imgfileid=\"100018223\" data-ratio=\"1\" data-s=\"300,640\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_B2jkicacLzPjw4xMSqVvoucZjonVDA-42.jpg\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAxVYfSsM0wdf9d3RpNiaTcHohxPNEVs2VFhPMukpU8lchxrvcB2jkicacLzPjw4xMSqVvoucZjonVDA\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"430\" style=\"width: 150px;height: 150px;\" \/><\/p>\n<section style=\"margin-left: 0pt;text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"letter-spacing: 1px;font-size: 16px;\"><\/span><o:page><\/o:page><\/section>\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: \u7b49\u7ebf;font-variant: normal;text-transform: none;letter-spacing: 1px;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010574\" data-ratio=\"0.43703703703703706\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_tDjYOUG2OQL0wrkWicr70aCJLc1MtQ.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTb4vroj0KdSMXORwMiaYpXqcD8uAeicbicJdARpSv3c37icjyYibtDjYOUG2OQL0wrkWicr70aCJLc1MtQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" height=\"241.8699951171875\" width=\"553.739990234375\" \/><\/span><\/section>\n<section style=\"text-align: justify;font-size: 10.5pt;font-family: \u7b49\u7ebf;font-weight: normal;margin-left: 21pt;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"letter-spacing: 1px;font-size: 16px;\"><span style=\"letter-spacing: 1px;font-family: Wingdings;font-variant: normal;text-transform: none;color: rgb(237, 125, 49);\">l<\/span><span style=\"letter-spacing: 1px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u9898\u76ee\uff1a\u5728 3P \u533b\u5b66\u80cc\u666f\u4e0b\uff0c\u57fa\u4e8e 101 \u7ec4\u5408\u673a\u5668\u5b66\u4e60\u8ba1\u7b97\u6846\u67b6\uff0c\u5bf9\u900f\u660e\u7ec6\u80de\u80be\u7ec6\u80de\u764c\u514d\u75ab\u539f\u6027\u7ec6\u80de\u6b7b\u4ea1\u76f8\u5173\u7279\u5f81\u7684\u591a\u7ec4\u5b66\u9274\u5b9a<\/span><\/span><\/section>\n<section style=\"text-align: justify;font-size: 10.5pt;font-family: \u7b49\u7ebf;font-weight: normal;margin-left: 21pt;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"letter-spacing: 1px;font-size: 16px;\"><span style=\"letter-spacing: 1px;font-family: Wingdings;font-variant: normal;text-transform: none;color: rgb(237, 125, 49);\">l<\/span><span style=\"letter-spacing: 1px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u6742\u5fd7\uff1aEPMA Journal<\/span><\/span><\/section>\n<section style=\"text-align: justify;font-size: 10.5pt;font-family: \u7b49\u7ebf;font-weight: normal;margin-left: 21pt;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"letter-spacing: 1px;font-size: 16px;\"><span style=\"letter-spacing: 1px;font-family: Wingdings;font-variant: normal;text-transform: none;color: rgb(237, 125, 49);\">l<\/span><span style=\"letter-spacing: 1px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u5f71\u54cd\u56e0\u5b50\uff1aIF=6.5<\/span><\/span><\/section>\n<section style=\"text-align: justify;font-size: 10.5pt;font-family: \u7b49\u7ebf;font-weight: normal;margin-left: 21pt;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"letter-spacing: 1px;font-size: 16px;\"><span style=\"letter-spacing: 1px;font-family: Wingdings;font-variant: normal;text-transform: none;color: rgb(237, 125, 49);\">l<\/span><span style=\"letter-spacing: 1px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u53d1\u8868\u65f6\u95f4\uff1a2023\u5e745\u6708<\/span><\/span><\/section>\n<section style=\"text-align: justify;font-size: 10.5pt;font-family: \u7b49\u7ebf;font-weight: normal;margin-left: 21pt;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"letter-spacing: 1px;font-size: 16px;\"><span style=\"letter-spacing: 1px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\"><span style=\"outline: 0px;font-size: 16px;font-weight: 700;text-indent: -28px;letter-spacing: 0.544px;font-family: system-ui, -apple-system, "system-ui", "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;background-color: rgb(255, 255, 255);color: rgb(0, 82, 255);\"><span style=\"outline: 0px;letter-spacing: 0.544px;\"><\/span><\/span><\/span><\/span><\/section>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 0);font-weight: bold;letter-spacing: 1px;font-size: 16px;\">\u7814\u7a76\u80cc\u666f<\/span><\/section>\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 0);letter-spacing: 1px;font-size: 16px;\">\u80be\u7ec6\u80de\u764c\u662f\u4e00\u79cd\u5e38\u89c1\u7684\u6076\u6027\u80bf\u7624\uff0c\u5176\u4e2d\u900f\u660e\u7ec6\u80de\u80be\u7ec6\u80de\u764c\u662f\u6700\u5e38\u89c1\u7684\u4e9a\u578b\u3002\u5c3d\u7ba1\u624b\u672f\u662f\u6700\u6709\u6548\u7684\u6cbb\u7597\u65b9\u6cd5\uff0c\u4f46\u90e8\u5206\u60a3\u8005\u4f1a\u51fa\u73b0\u8f6c\u79fb\u3002\u514d\u75ab\u7597\u6cd5\u6210\u4e3a\u4e00\u79cd\u6709\u524d\u9014\u7684\u6cbb\u7597\u65b9\u6cd5\uff0c\u4f46\u4ec5\u5c11\u6570\u60a3\u8005\u83b7\u76ca\u3002\u7ec6\u80de\u6b7b\u4ea1\u547d\u540d\u59d4\u5458\u4f1a\u5b9a\u4e49\u4e86\u591a\u79cd\u5f62\u5f0f\u7684\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea1\uff0c\u5176\u4e2d\u514d\u75ab\u539f\u6027\u7ec6\u80de\u6b7b\u4ea1\u5bf9\u514d\u75ab\u7684\u8c03\u8282\u81f3\u5173\u91cd\u8981\u3002\u8bf1\u5bfc\u514d\u75ab\u539f\u6027\u7ec6\u80de\u6b7b\u4ea1\u88ab\u8ba4\u4e3a\u662f\u4e00\u79cd\u6709\u524d\u9014\u7684\u6297\u764c\u514d\u75ab\u6cbb\u7597\u7b56\u7565\uff0c\u53ef\u80fd\u6210\u4e3a\u60a3\u8005\u9884\u540e\u548c\u6cbb\u7597\u53cd\u5e94\u7684\u751f\u7269\u6807\u5fd7\u7269\u3002<\/span><\/section>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;letter-spacing: 1px;font-size: 16px;\">\u6570\u636e\u6765\u6e90<\/span><\/section>\n<table border=\"1\" cellspacing=\"0\" cellpadding=\"0\" width=\"568\" style=\"border-width: initial;border-style: none;border-color: initial;border-collapse: collapse;width: 100%;\">\n<tbody>\n<tr>\n<td width=\"102\" valign=\"top\" style=\"width:76.3pt;background:#5B9BD5;border-top:solid #5B9BD5 1.0pt;mso-border-top-alt:solid #5B9BD5 0.5pt;border-left:solid #5B9BD5 1.0pt;mso-border-left-alt:solid #5B9BD5 0.5pt;border-bottom:solid #5B9BD5 1.0pt;mso-border-bottom-alt:solid #5B9BD5 0.5pt;border-right:none;padding:0pt 5.4pt 0pt 5.4pt;\">\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: "Microsoft YaHei UI";font-variant: normal;text-transform: none;color: rgb(51, 51, 51);letter-spacing: 1px;font-size: 16px;\">\u6570\u636e\u96c6\/\u961f\u5217<\/span><\/section>\n<\/td>\n<td width=\"94\" valign=\"top\" style=\"width:70.85pt;background:#5B9BD5;border-top:solid #5B9BD5 1.0pt;mso-border-top-alt:solid #5B9BD5 0.5pt;border-left:solid #9CC2E5 1.0pt;mso-border-left-alt:solid #9CC2E5 0.5pt;border-bottom:solid #5B9BD5 1.0pt;mso-border-bottom-alt:solid #5B9BD5 0.5pt;border-right:none;padding:0pt 5.4pt 0pt 5.4pt;\">\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: "Microsoft YaHei UI";font-variant: normal;text-transform: none;color: rgb(51, 51, 51);letter-spacing: 1px;font-size: 16px;\">\u6570\u636e\u5e93<\/span><\/section>\n<\/td>\n<td width=\"132\" valign=\"top\" style=\"width:99.25pt;background:#5B9BD5;border-top:solid #5B9BD5 1.0pt;mso-border-top-alt:solid #5B9BD5 0.5pt;border-left:solid #9CC2E5 1.0pt;mso-border-left-alt:solid #9CC2E5 0.5pt;border-bottom:solid #5B9BD5 1.0pt;mso-border-bottom-alt:solid #5B9BD5 0.5pt;border-right:none;padding:0pt 5.4pt 0pt 5.4pt;\">\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: "Microsoft YaHei UI";font-variant: normal;text-transform: none;color: rgb(51, 51, 51);letter-spacing: 1px;font-size: 16px;\">\u6570\u636e\u7c7b\u578b<\/span><\/section>\n<\/td>\n<td width=\"240\" valign=\"top\" style=\"width:179.7pt;background:#5B9BD5;border-top:solid #5B9BD5 1.0pt;mso-border-top-alt:solid #5B9BD5 0.5pt;border-left:solid #9CC2E5 1.0pt;mso-border-left-alt:solid #9CC2E5 0.5pt;border-bottom:solid #5B9BD5 1.0pt;mso-border-bottom-alt:solid #5B9BD5 0.5pt;border-right:solid #5B9BD5 1.0pt;mso-border-right-alt:solid #5B9BD5 0.5pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: "Microsoft YaHei UI";font-variant: normal;text-transform: none;color: rgb(51, 51, 51);letter-spacing: 1px;font-size: 16px;\">\u8be6\u7ec6\u4fe1\u606f<\/span><\/section>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"102\" valign=\"top\" style=\"width:76.3pt;background:#DEEAF6;border-top:solid #9CC2E5 1.0pt;mso-border-top-alt:solid #9CC2E5 0.5pt;border-left:solid #9CC2E5 1.0pt;mso-border-left-alt:solid #9CC2E5 0.5pt;border-bottom:solid #9CC2E5 1.0pt;mso-border-bottom-alt:solid #9CC2E5 0.5pt;border-right:solid #9CC2E5 1.0pt;mso-border-right-alt:solid #9CC2E5 0.5pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(51, 51, 51);font-weight: normal;letter-spacing: 1px;font-size: 16px;\">GSE53757<\/span><\/section>\n<\/td>\n<td width=\"94\" valign=\"top\" style=\"width:70.85pt;background:#DEEAF6;border-top:solid #9CC2E5 1.0pt;mso-border-top-alt:solid #9CC2E5 0.5pt;border-left:solid #9CC2E5 1.0pt;mso-border-left-alt:solid #9CC2E5 0.5pt;border-bottom:solid #9CC2E5 1.0pt;mso-border-bottom-alt:solid #9CC2E5 0.5pt;border-right:solid #9CC2E5 1.0pt;mso-border-right-alt:solid #9CC2E5 0.5pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(51, 51, 51);letter-spacing: 1px;font-size: 16px;\">GEO<\/span><\/section>\n<\/td>\n<td width=\"132\" valign=\"top\" style=\"width:99.25pt;background:#DEEAF6;border-top:solid #9CC2E5 1.0pt;mso-border-top-alt:solid #9CC2E5 0.5pt;border-left:solid #9CC2E5 1.0pt;mso-border-left-alt:solid #9CC2E5 0.5pt;border-bottom:solid #9CC2E5 1.0pt;mso-border-bottom-alt:solid #9CC2E5 0.5pt;border-right:solid #9CC2E5 1.0pt;mso-border-right-alt:solid #9CC2E5 0.5pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(51, 51, 51);letter-spacing: 1px;font-size: 16px;\">RNA-seq\u6570\u636e<\/span><\/section>\n<\/td>\n<td width=\"240\" valign=\"top\" style=\"width:179.7pt;background:#DEEAF6;border-top:solid #9CC2E5 1.0pt;mso-border-top-alt:solid #9CC2E5 0.5pt;border-left:solid #9CC2E5 1.0pt;mso-border-left-alt:solid #9CC2E5 0.5pt;border-bottom:solid #9CC2E5 1.0pt;mso-border-bottom-alt:solid #9CC2E5 0.5pt;border-right:solid #9CC2E5 1.0pt;mso-border-right-alt:solid #9CC2E5 0.5pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(51, 51, 51);letter-spacing: 1px;font-size: 16px;\">72\u4e2accRCC\u6837\u672c\u548c72\u4e2a\u6b63\u5e38\u6837\u672c<\/span><\/section>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"102\" valign=\"top\" style=\"width:76.3pt;border-top:solid #9CC2E5 1.0pt;mso-border-top-alt:solid #9CC2E5 0.5pt;border-left:solid #9CC2E5 1.0pt;mso-border-left-alt:solid #9CC2E5 0.5pt;border-bottom:solid #9CC2E5 1.0pt;mso-border-bottom-alt:solid #9CC2E5 0.5pt;border-right:solid #9CC2E5 1.0pt;mso-border-right-alt:solid #9CC2E5 0.5pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"letter-spacing: 1px;font-size: 16px;\"><span style=\"letter-spacing: 1px;font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(51, 51, 51);font-weight: normal;\">GSE36895<\/span>        <\/span><o:page><\/o:page><\/section>\n<\/td>\n<td width=\"94\" valign=\"top\" style=\"width:70.85pt;border-top:solid #9CC2E5 1.0pt;mso-border-top-alt:solid #9CC2E5 0.5pt;border-left:solid #9CC2E5 1.0pt;mso-border-left-alt:solid #9CC2E5 0.5pt;border-bottom:solid #9CC2E5 1.0pt;mso-border-bottom-alt:solid #9CC2E5 0.5pt;border-right:solid #9CC2E5 1.0pt;mso-border-right-alt:solid #9CC2E5 0.5pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(51, 51, 51);letter-spacing: 1px;font-size: 16px;\">GEO<\/span><\/section>\n<\/td>\n<td width=\"132\" valign=\"top\" style=\"width:99.25pt;border-top:solid #9CC2E5 1.0pt;mso-border-top-alt:solid #9CC2E5 0.5pt;border-left:solid #9CC2E5 1.0pt;mso-border-left-alt:solid #9CC2E5 0.5pt;border-bottom:solid #9CC2E5 1.0pt;mso-border-bottom-alt:solid #9CC2E5 0.5pt;border-right:solid #9CC2E5 1.0pt;mso-border-right-alt:solid #9CC2E5 0.5pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(51, 51, 51);letter-spacing: 1px;font-size: 16px;\">RNA-seq\u6570\u636e<\/span><\/section>\n<\/td>\n<td width=\"240\" valign=\"top\" style=\"width:179.7pt;border-top:solid #9CC2E5 1.0pt;mso-border-top-alt:solid #9CC2E5 0.5pt;border-left:solid #9CC2E5 1.0pt;mso-border-left-alt:solid #9CC2E5 0.5pt;border-bottom:solid #9CC2E5 1.0pt;mso-border-bottom-alt:solid #9CC2E5 0.5pt;border-right:solid #9CC2E5 1.0pt;mso-border-right-alt:solid #9CC2E5 0.5pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(51, 51, 51);letter-spacing: 1px;font-size: 16px;\">9\u4e2accRCC\u6837\u672c\u548c23\u4e2a\u6b63\u5e38\u6837\u672c<\/span><\/section>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;letter-spacing: 1px;font-size: 16px;\">\u7814\u7a76\u601d\u8def<\/span><\/section>\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;letter-spacing: 1px;font-size: 16px;\">\u901a\u8fc7\u8bc4\u4f30\u5171\u8bc6\u514d\u75ab\u539f\u6027\u7ec6\u80de\u6b7b\u4ea1\u76f8\u5173\u7279\u5f81\uff08ICDRS\uff09\u662f\u5426\u80fd\u9884\u6d4b\u900f\u660e\u7ec6\u80de\u80be\u7ec6\u80de\u764c\uff08ccRCC\uff09\u7684\u53d1\u751f\u3001\u53d1\u5c55\u548c\u8f6c\u79fb\u4ee5\u4fc3\u8fdbICDRS\u7684\u5e94\u7528\uff1b\u518d\u6784\u5efa\u4e86ICDRS\u6574\u5408\u5217\u7ebf\u56fe\uff0c\u4e3a\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u6bcf\u4f4d\u60a3\u8005\u7684\u9884\u540e\u63d0\u4f9b\u5b9a\u91cf\u5de5\u5177\u3002ICDRS\u7684\u673a\u5236\u7814\u7a76\u5728\u5927\u91cf\u8f6c\u5f55\u7ec4\u3001\u57fa\u56e0\u7ec4\u548c\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u6c34\u5e73\u4e0a\u8fdb\u884c\uff0c\u63ed\u793a\u4e86ICDRS\u4e0eccRCC\u7684\u9884\u540e\u548c\u514d\u75ab\u72b6\u6001\u4e4b\u95f4\u7684\u5bc6\u5207\u5173\u8054\u3002\u6700\u540e\u8fdb\u4e00\u6b65\u7814\u7a76\u4e86\u4e0d\u540c\u98ce\u9669\u4e9a\u7ec4\u5bf9\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\uff08ICI\uff09\u6cbb\u7597\u7684\u53cd\u5e94\u4ee5\u53ca\u5bf9RCC\u4e00\u7ebf\u836f\u7269\u7684\u654f\u611f\u6027\uff0c\u5305\u62ec\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\uff08TKI\uff09\u548c mTOR \u6291\u5236\u5242\u3002<\/span><\/section>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;letter-spacing: 1px;font-size: 16px;\">\u4e3b\u8981\u7ed3\u679c<\/span><\/section>\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"letter-spacing: 1px;font-size: 16px;\"><span style=\"letter-spacing: 1px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: bold;\">1.<\/span><span style=\"letter-spacing: 1px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u5355\u7ec6\u80de\u514d\u75ab\u539f\u6027\u7ec6\u80de\u6b7b\u4ea1\u7279\u5f81\u5206\u6790<\/span><\/span><\/section>\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"letter-spacing: 1px;font-size: 16px;\"><span style=\"letter-spacing: 1px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u5bf9\u65e9\u671fccRCC\u60a3\u8005\u8fdb\u884c\u4e86\u5355\u7ec6\u80deRNA\u6d4b\u5e8f\uff0c\u5f97\u5230\u4e8634,155\u4e2a\u7ec6\u80de\u6570\u636e\u3002\u4f7f\u7528Harmony\u5305\u6d88\u9664\u6279\u91cf\u6548\u5e94\uff0c\u6210\u529f\u6574\u5408\u4e03\u4e2a\u6837\u672c\uff08\u56fe1a\uff0cb\uff09\u3002\u8fdb\u884c\u4e3b\u6210\u5206\u5206\u6790\uff08PCA\uff09\u548ct-SNE\u964d\u7ef4\uff0c\u5c06\u7ec6\u80de\u805a\u5408\u621040\u4e2a\u7c07\uff0c\u6807\u8bb0\u4e3a10\u4e2a\u4e3b\u8981\u7ec6\u80de\u7c7b\u578b\uff08\u56fe1c\uff09\u3002\u7814\u7a76\u5c55\u793a\u4e86\u6bcf\u4e2a\u7ec6\u80de\u7fa4\u7684\u6807\u8bb0\u57fa\u56e0\u3002<\/span>    <\/span><o:page><\/o:page><\/section>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: \u7b49\u7ebf;font-variant: normal;text-transform: none;letter-spacing: 1px;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010576\" data-ratio=\"0.7361111111111112\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_nmDiaia0DrO9tpaIKZAibUMUl4pwcA.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTb4vroj0KdSMXORwMiaYpXqOiayOxbZQib1qsM42AgeD57ALadDpnmDiaia0DrO9tpaIKZAibUMUl4pwcA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" height=\"417.3399658203125\" width=\"566.9600219726562\" \/><\/span><\/section>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;letter-spacing: 1px;font-size: 16px;\">\u56fe1\u5355\u7ec6\u80de\u514d\u75ab\u539f\u6027\u7ec6\u80de\u6b7b\u4ea1\u7279\u5f81\u5206\u6790<\/span><\/section>\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: bold;letter-spacing: 1px;font-size: 16px;\">2. \u4e0eICD\u76f8\u5173\u7684\u67a2\u7ebd\u6a21\u5757\u548c\u57fa\u56e0\u5206\u6790<\/span><\/section>\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"letter-spacing: 1px;font-size: 16px;\"><span style=\"letter-spacing: 1px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u4f7f\u7528ssGSEA\u7b97\u6cd5\u8bc4\u4f30TCGA-KIRC\u6570\u636e\u96c6\u4e2d\u6bcf\u4e2a\u6837\u54c1\u7684ICD\u6d3b\u6027\u8bc4\u5206\uff0c\u5e76\u5c06\u5176\u4f5c\u4e3a\u540e\u7eedWGCNA\u5206\u6790\u7684\u8868\u578b\u6570\u636e\u3002\u5229\u7528WGCNA\u5206\u6790\u786e\u5b9a\u4e0eICD\u5206\u6570\u663e\u7740\u76f8\u5173\u7684\u6a21\u5757\uff0c\u5728\u5355\u7ec6\u80de\u6c34\u5e73\u9274\u5b9a\u51fa836\u4e2aICD\u76f8\u5173DEG\uff0c\u6784\u5efa\u5171\u8868\u8fbe\u7f51\u7edc\uff08\u56fe2a\uff09\u3002\u901a\u8fc7\u8c03\u6574\u53c2\u6570\u9009\u62e9\u6700\u4f73\u8f6f\u9608\u503c\u548c\u6784\u5efa\u5171\u8868\u8fbe\u7f51\u7edc\uff08\u56fe2b\uff09\uff0c\u6700\u7ec8\u83b7\u5f97\u56db\u4e2a\u6a21\u5757\uff0c\u5176\u4e2dMEblue\u6a21\u5757\u4e0eICD\u8bc4\u5206\u5bc6\u5207\u76f8\u5173\uff08\u56fe2c\uff09;\u6b64\u5916\uff0c\u84dd\u8272\u6a21\u5757\u7684\u57fa\u56e0\u663e\u8457\u6027\uff08GS\uff09\u4e0e\u6a21\u5757\u96b6\u5c5e\u5ea6\uff08MM\uff09\u7684\u6563\u70b9\u56fe\u663e\u793a\u51fa\u663e\u8457\u7684\u76f8\u5173\u6027\uff08\u56fe2d\uff09\u3002\u5728\u6279\u91cfRNA\u6d4b\u5e8f\u4e2d\uff0c\u5efa\u7acbTCGA-KIRC\u80bf\u7624\u548c\u6b63\u5e38\u80be\u7ec4\u7ec7\u4e2d\u7684\u5dee\u5f02\u8868\u8fbe\u57fa\u56e0\uff08\u56fe2e\uff09,MEblue\u6a21\u5757\u4e2d\u7684\u57fa\u56e0\u4e0e\u514d\u75ab\u539f\u6027\u7ec6\u80de\u6b7b\u4ea1\u76f8\u5173\uff0c\u7ecf\u8fc7\u4ea4\u53c9\u5206\u6790\u9274\u5b9a\u51fa131\u4e2aICDRgenes\uff08\u56fe2f\uff09\u3002\u5bf9131\u4e2aICDRgenes\u8fdb\u884c\u5355\u56e0\u7d20Cox\u56de\u5f52\u5206\u6790\uff0c\u9274\u5b9a\u51fa39\u4e2a\u663e\u8457\u57fa\u56e0\uff0c\u8fdb\u4e00\u6b65\u4e0e\u5916\u90e8\u6570\u636e\u96c6\u8fdb\u884c\u9a8c\u8bc1\u5e76\u63d0\u53d6\u5171\u4eab\u57fa\u56e0\uff08\u56fe2h\uff09\u3002\u5206\u6790\u8fd9\u4e9b\u57fa\u56e0\u7684\u62f7\u8d1d\u6570\u53d8\u5f02\u9891\u7387\uff0c\u53d1\u73b0\u5176\u4e2dRNF130\u7684\u62f7\u8d1d\u6570\u589e\u52a0\u8d85\u8fc722%\uff08\u56fe2i\uff09\u3002<\/span>    <\/span><o:page><\/o:page><\/section>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: \u7b49\u7ebf;font-variant: normal;text-transform: none;letter-spacing: 1px;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010578\" data-ratio=\"0.275\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_vkRwKsZzeaibN3VL6dzsjxg6zmYDCw.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTb4vroj0KdSMXORwMiaYpXqChXo2icf5GB5bwk09mLib1JcicXGvkRwKsZzeaibN3VL6dzsjxg6zmYDCw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" height=\"159.33999633789062\" width=\"579.9500122070312\" \/><\/span><\/section>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: \u7b49\u7ebf;font-variant: normal;text-transform: none;letter-spacing: 1px;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010575\" data-ratio=\"0.3425925925925926\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_CueRr62hxB2F2oBykmPoRx4diaiaCw.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTb4vroj0KdSMXORwMiaYpXqibYWaiaibfjBuvoia7ibcABI0OJnZWbCueRr62hxB2F2oBykmPoRx4diaiaCw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" height=\"206.67001342773438\" width=\"602.530029296875\" \/><\/span><\/section>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: \u7b49\u7ebf;font-variant: normal;text-transform: none;letter-spacing: 1px;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010577\" data-ratio=\"0.6888888888888889\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_0kYH6Liaj6AWThouAEvDX9AE8C41LA.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTb4vroj0KdSMXORwMiaYpXquwHtZLOUiaYCX60N6VCicnrhicK60kYH6Liaj6AWThouAEvDX9AE8C41LA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" height=\"393.57000732421875\" width=\"571.0\" \/><\/span><\/section>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"letter-spacing: 1px;font-size: 16px;\"><span style=\"letter-spacing: 1px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u56fe2 \u4e0eICD\u76f8\u5173\u7684\u67a2\u7ebd\u6a21\u5757\u548c\u57fa\u56e0\u5206\u6790<\/span>    <\/span><o:page><\/o:page><\/section>\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: bold;letter-spacing: 1px;font-size: 16px;\">3. \u96c6\u6210\u673a\u5668\u5b66\u4e60\u7684\u9884\u540e\u6a21\u578b\u6784\u5efa<\/span><\/section>\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"letter-spacing: 1px;font-size: 16px;\"><span style=\"letter-spacing: 1px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u901a\u8fc7\u4f7f\u7528101\u79cd\u673a\u5668\u5b66\u4e60\u7b97\u6cd5\u5206\u6790\u4ece\u5355\u53d8\u91cfCox\u56de\u5f52\u5206\u6790\u4e2d\u83b7\u5f97\u768437\u4e2a\u9884\u540e\u57fa\u56e0\uff0c\u6784\u5efa\u4e86\u5171\u8bc6\u514d\u75ab\u539f\u6027\u7ec6\u80de\u6b7b\u4ea1\u76f8\u5173\u7b7e\u540d\uff08ICDRS\uff09\uff08\u56fe3a\uff09\u3002\u4f7f\u7528\u5341\u500d\u4ea4\u53c9\u9a8c\u8bc1\u6846\u67b6\u548c\u6700\u5c0f\u5316\u90e8\u5206\u4f3c\u7136\u504f\u5dee\uff0c\u786e\u5b9a\u4e86 LASSO \u5206\u6790\u4e2d\u7684\u6700\u4f73 \u03bb \u503c 0.035695\uff08\u56fe3b\uff0cc\uff09\u3002\u901a\u8fc7\u5c06\u516d\u4e2a\u57fa\u56e0\u7684\u8868\u8fbe\u4e0eCox\u6a21\u578b\u4e2d\u7684\u56de\u5f52\u7cfb\u6570\u8fdb\u884c\u52a0\u6743\u6765\u8ba1\u7b97\u6bcf\u4e2a\u60a3\u8005\u7684\u98ce\u9669\u8bc4\u5206\uff08\u56fe3d\uff09\uff0c\u8fd9\u6837\u80fd\u591f\u6839\u636e\u4e2d\u4f4d\u98ce\u9669\u8bc4\u5206\u5c06\u6240\u6709\u60a3\u8005\u5206\u914d\u5230\u9ad8\u98ce\u9669\u7ec4\u6216\u4f4e\u98ce\u9669\u7ec4\u3002\u901a\u8fc7LASSO\u5206\u6790\u4e2d\u7cfb\u6570\u4e3a\u975e\u96f6\u7684\u57fa\u56e0\u8fdb\u884c\u9010\u6b65Cox\u6bd4\u4f8b\u98ce\u9669\u56de\u5f52\u5206\u6790\uff08\u5411\u540e\uff09\u9274\u5b9a\u51fa\u4e00\u7ec46\u4e2a\u57fa\u56e0\uff08\u56fe3e\uff09\u3002\u540c\u65f6\uff0c\u968f\u7740\u98ce\u9669\u8bc4\u5206\u7684\u589e\u52a0\uff0c\u6b7b\u4ea1\u60a3\u8005\u7684\u6570\u91cf\u4e5f\u9010\u6e10\u589e\u52a0\uff08\u56fe3f\uff09\u3002\u6b64\u5916\uff0c\u5728\u8bad\u7ec3\u96c6\u3001\u5185\u90e8\u9a8c\u8bc1\u96c6\u548c E-MTAB-1980 \u6570\u636e\u96c6\u4e2d\uff0c\u9ad8\u5371\u7ec4\u60a3\u8005\u7684\u603b\u751f\u5b58\u671f \uff08OS\uff09 \u660e\u663e\u4f4e\u4e8e\u4f4e\u5371\u7ec4\uff08p < 0.001;\u56fe3g-i\uff09\u3002\u540c\u6837\uff0c\u4f4e\u98ce\u9669\u7ec4\u7684\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u548c\u75be\u75c5\u7279\u5f02\u6027\u751f\u5b58\u671f\uff08DSS\uff09\u663e\u8457\u4f18\u4e8e\u9ad8\u98ce\u9669\u7ec4\uff08p < 0.001;\u56fe 3j\uff0ck\uff09\u3002<\/span>    <\/span><o:page><\/o:page><\/section>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: \u7b49\u7ebf;font-variant: normal;text-transform: none;letter-spacing: 1px;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010583\" data-ratio=\"1.1268518518518518\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_9Ow8viaRmsZPlmdND7BDLjvL3ib4Dw.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTb4vroj0KdSMXORwMiaYpXqcNN0Erwjl4QXAa1FwOp8V7lYcS9Ow8viaRmsZPlmdND7BDLjvL3ib4Dw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" height=\"634.4400634765625\" width=\"563.0599975585938\" \/><\/span><\/section>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;letter-spacing: 1px;font-size: 16px;\">\u56fe3 Hub\u57fa\u56e0\u7684\u8bc6\u522b<\/span><\/section>\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: bold;letter-spacing: 1px;font-size: 16px;\">4. ICDRS\u6a21\u578b\u6027\u80fd\u5206\u6790<\/span><\/section>\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;letter-spacing: 1px;font-size: 16px;\">ICDRS\u5728\u8bad\u7ec3\u96c6\u3001\u5185\u90e8\u9a8c\u8bc1\u96c6\u548cE-MTAB-1980\u6570\u636e\u96c6\u4e2d\u5c55\u73b0\u51fa\u8f83\u5f3a\u7684\u8fa8\u522b\u80fd\u529b\uff0c\u5176\u66f2\u7ebf\u4e0b\u9762\u79ef\u5206\u522b\u4e3a0.746\u81f30.808\u30010.760\u81f30.723\u548c0.827\u81f30.732\uff08\u56fe4a-c\uff09\u3002\u4e0e\u5176\u4ed6\u4e34\u5e8a\u7279\u5f81\u76f8\u6bd4\uff0cICDRS\u7684AUC\u663e\u8457\u66f4\u4f18\u3002\u901a\u8fc7\u8bc4\u4f30ICDRS\u4e0e\u4e34\u5e8a\u7279\u5f81\u5728ccRCC\u60a3\u8005\u9884\u540e\u8bc4\u4f30\u4e2d\u7684\u76f8\u5173\u6027\uff0c\u89c2\u5bdf\u5230\u9ad8\u5371\u7ec4\u548c\u4f4e\u5371\u7ec4\u5728\u7b49\u7ea7\u3001\u5206\u671f\u3001T\u548cM\u5206\u5e03\u4e0a\u5b58\u5728\u663e\u8457\u5dee\u5f02\uff08\u56fe4d\uff0cf\uff09\u3002M1\u3001III-IV\u671f\u3001G3-4\u548cT3-4\u60a3\u8005\u7684\u98ce\u9669\u8bc4\u5206\u660e\u663e\u9ad8\u4e8eM0\u3001I-II\u671f\u3001G1-2\u548cT1-2\u60a3\u8005\uff08\u56fe4e\uff09\u3002\u8fd9\u4e9b\u53d1\u73b0\u6697\u793aICDRS\u53ef\u80fd\u4e0eccRCC\u60a3\u8005\u7684\u4e0d\u826f\u9884\u540e\u76f8\u5173\u3002\u6b64\u5916\uff0cICDRS \u9884\u6d4b ccRCC \u60a3\u8005 M \u671f\u7684 AUC \u4e3a 0.721\uff08\u56fe4g\uff0ch\uff09\uff0c\u8868\u660e\u5176\u5728\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u9884\u6d4b ccRCC \u8f6c\u79fb\u53d1\u5c55\u7684\u6f5c\u5728\u5e94\u7528\u3002\u901a\u8fc7KM\u66f2\u7ebf\u5206\u6790\uff0cICDRS\u5728\u6309\u5404\u79cd\u4e34\u5e8a\u7279\u5f81\uff08\u5305\u62ec\u5e74\u9f84\u3001\u6027\u522b\u3001\u5206\u671f\u3001\u5206\u7ea7\u548cT\uff09\u5206\u5c42\u7684\u4e9a\u7ec4\u4e2d\u8868\u73b0\u51fa\u5f3a\u5927\u7684ccRCC\u9884\u540e\u80fd\u529b\uff08\u56fe4i-l\uff09\u3002<\/span><span style=\"letter-spacing: 1px;font-size: 16px;\">    <\/span><o:page><\/o:page><\/section>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: \u7b49\u7ebf;font-variant: normal;text-transform: none;letter-spacing: 1px;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010579\" data-ratio=\"0.32037037037037036\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_x49kPmFwGVz0bm6f3dILrjxjUia59A.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTb4vroj0KdSMXORwMiaYpXqVEHjvWpKMxnVRbI09ZIQMiaPr5x49kPmFwGVz0bm6f3dILrjxjUia59A\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" height=\"184.02996826171875\" width=\"574.010009765625\" \/><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010582\" data-ratio=\"0.425\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/10_8ZFTp06Vog2qTgcr5hFMjjYsqVXJcA.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTb4vroj0KdSMXORwMiaYpXqzlFJgJ9IzP89OD3m4okf0XuV8ZFTp06Vog2qTgcr5hFMjjYsqVXJcA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" height=\"248.66998291015625\" width=\"584.6199951171875\" \/><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010581\" data-ratio=\"0.5148148148148148\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/11_MP1nb1F7azoaSaicmZanRWsQd5vobw.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTb4vroj0KdSMXORwMiaYpXqJVPHYY2HxuvaMYQjnCUjzxH5zMP1nb1F7azoaSaicmZanRWsQd5vobw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" height=\"274.2300109863281\" width=\"532.6700439453125\" \/><\/span><span style=\"letter-spacing: 1px;font-size: 16px;\">    <\/span><o:page><\/o:page><\/section>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;letter-spacing: 1px;font-size: 16px;\">\u56fe4 ICDRS\u6a21\u578b\u6027\u80fd\u5206\u6790<\/span><\/section>\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: bold;letter-spacing: 1px;font-size: 16px;\">5. ICDRS\u6a21\u578b\u4e34\u5e8a\u7279\u5f81\u6548\u679c\u5206\u6790<\/span><\/section>\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"letter-spacing: 1px;font-size: 16px;\"><span style=\"letter-spacing: 1px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u901a\u8fc7\u5bf9TCGA-KIRC \u6570\u636e\u96c6\u4e2d\u7684 OS\u3001PFS \u548c DSS \u8fdb\u884c\u5355\u56e0\u7d20\u548c\u591a\u56e0\u7d20 Cox \u56de\u5f52\u5206\u6790\u3002\u5728\u5355\u56e0\u7d20\u5206\u6790\u4e2d\uff0cICDRS\u662fOS\u3001PFS\u548cDSS\u7684\u91cd\u8981\u5371\u9669\u56e0\u7d20\uff1b\u5728\u591a\u56e0\u7d20\u5206\u6790\u4e2d\uff0cICDRS\u4ecd\u7136\u662fOS\u3001PFS\u548cDSS\u7684\u72ec\u7acb\u9884\u540e\u56e0\u7d20\uff0c\u8868\u660e\u5176\u5728ccRCC\u60a3\u8005\u4e2d\u5177\u6709\u5f3a\u5927\u7684\u9884\u540e\u80fd\u529b\uff08\u56fe5a-c\uff09\u3002\u901a\u8fc7\u5bf9E-MTAB-1980 \u6570\u636e\u96c6\u4e2d\u7684 OS \u8fdb\u884c\u4e86\u5355\u56e0\u7d20\u548c\u591a\u56e0\u7d20 Cox \u56de\u5f52\u5206\u6790\uff08\u56fe5d\uff09,\u8868\u660eICDRS\u662fccRCC\u60a3\u8005\u7684\u72ec\u7acb\u9884\u540e\u56e0\u7d20\u3002\u6839\u636eICDRS\u548c\u4e34\u5e8a\u7279\u5f81\u6784\u5efa\u7684\u5217\u7ebf\u56fe\uff08\u56fe5e\uff09\u5728ccRCC\u7684\u4e2a\u6027\u5316\u9884\u540e\u9884\u6d4b\u4e2d\u663e\u793a\u51fa\u8f83\u9ad8\u7684\u9884\u6d4b\u51c6\u786e\u6027\uff0c\u5177\u6709\u7a33\u5b9a\u548c\u7a33\u5065\u7684\u9884\u6d4b\u80fd\u529b\uff0c\u4f18\u4e8e\u5176\u4ed6\u4e34\u5e8a\u7279\u5f81\uff08\u56fe5f\uff09\u3002\u8be5\u5217\u7ebf\u56fe\u57281\u5e74\u30013\u5e74\u548c5\u5e74\u95f4\u9694\u5185\u7684AUC\u5206\u522b\u8fbe\u52300.867\u30010.830\u548c0.814\uff0c\u51b3\u7b56\u66f2\u7ebf\u5206\u6790\u663e\u793a\u5176\u5177\u6709\u66f4\u597d\u7684\u51c0\u4e34\u5e8a\u83b7\u76ca\uff0c\u4e3a\u4e34\u5e8a\u5b9e\u8df5\u63d0\u4f9b\u4e86\u53ef\u9760\u7684\u5de5\u5177\uff08\u56fe5g-i\uff09\u3002<\/span>    <\/span><o:page><\/o:page><\/section>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: \u7b49\u7ebf;font-variant: normal;text-transform: none;letter-spacing: 1px;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010580\" data-ratio=\"0.4583333333333333\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/12_Rpw3bl24Zlygib7OqF9qd7ZbIJ3OIw.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTb4vroj0KdSMXORwMiaYpXqn0ZlickM1Be3Rp0ichQQnLA1WhSRpw3bl24Zlygib7OqF9qd7ZbIJ3OIw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" height=\"245.85000610351562\" width=\"536.239990234375\" \/><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010585\" data-ratio=\"0.42592592592592593\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/13_RcZ9iahrib5WO1byUhuSkuAibYSWMQ.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTb4vroj0KdSMXORwMiaYpXqB676WoQ1xFPaIicFUYgkaFU7lIseRcZ9iahrib5WO1byUhuSkuAibYSWMQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" height=\"235.80001831054688\" width=\"553.739990234375\" \/><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010584\" data-ratio=\"0.28888888888888886\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/14_nH5Te9ENgAt7orPkWMkHjRdTodqcXQ.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTb4vroj0KdSMXORwMiaYpXqZicufqBtU9b9x0HSXKBibib4lCvnH5Te9ENgAt7orPkWMkHjRdTodqcXQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" height=\"159.739990234375\" width=\"553.739990234375\" \/><\/span><\/section>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;letter-spacing: 1px;font-size: 16px;\">\u56fe5 ICDRS\u6a21\u578b\u4e34\u5e8a\u7279\u5f81\u6548\u679c\u5206\u6790<\/span><\/section>\n<section style=\"text-align: center;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;letter-spacing: 1px;font-size: 16px;\">\u6587\u7ae0\u5c0f\u7ed3<\/span><\/section>\n<section style=\"text-align: justify;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;text-indent: 0em;\"><span style=\"letter-spacing: 1px;font-size: 16px;\"><span style=\"letter-spacing: 1px;font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u770b\u5b8c\u8fd9\u7bc7\u6587\u7ae0\u601d\u8def\u6709\u6ca1\u6709\u89c9\u5f97\u80bf\u7624\u514d\u75ab\u65b9\u5411\u7684\u7814\u7a76\u8fd8\u6709\u5f88\u591a\u53ef\u505a\u4e4b\u5904\uff1f\u8fd9\u7bc7\u6587\u7ae0\u901a\u8fc7\u5229\u7528\u53ef\u516c\u5f00\u83b7\u53d6\u7684\u5927\u6837\u672c\u91cf\u4e34\u5e8a\u6570\u636e\uff0c\u540c\u65f6\u5229\u7528\u751f\u4fe1+\u5b9e\u9a8c\u76f8\u7ed3\u5408\u7684\u65b9\u6cd5\uff0c\u65e2\u53ef\u4ee5\u7701\u4e00\u5b9a\u7684\u65f6\u95f4\u548c\u7ecf\u8d39\uff0c\u53c8\u53ef\u4ee5\u4e30\u5bcc\u6587\u7ae0\uff0c\u518d\u7ed3\u5408\u4f7f\u7528\u591a\u79cd\u673a\u5668\u5b66\u4e60\u53ca\u5176\u7ec4\u5408\u5c31\u53ef\u5b8c\u6210\u8fd9\u7bc7<\/span><span style=\"letter-spacing: 1px;font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\">6\u5206+\u7684\u7eaf\u6570\u636e\u5206\u6790\u6587\u7ae0\u3002<\/span><span style=\"letter-spacing: 1px;font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;background: rgb(255, 255, 0);\">\u60f3\u5728\u80bf\u7624\u514d\u75ab\u65b9\u5411\u505a\u70b9\u65b0\u4e1c\u897f\u7684\u5c0f\u4f19\u4f34\uff0c\u4e0d\u8981\u9519\u8fc7\u8fd9\u4e2a\u597d\u601d\u8def\uff0c\u53ef\u4ee5\u6362\u4e2a\u764c\u79cd\u590d\u73b0\uff0c\u8fd8\u53ef\u4ee5\u62d3\u5c55\u505a\u56fd\u81ea\u7136\u8bfe\u9898\uff0c\u4e00\u4e3e\u4e24\u5f97\uff0c\u6709\u9700\u8981\u7684\u5c0f\u4f19\u4f34\u53ef\u4ee5\u6765\u627e\u5c0f\u9014\u505a\u8bbe\u8ba1\u54df<\/span><span style=\"letter-spacing: 1px;font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;background: rgb(255, 255, 0);\">~<\/span>  <\/span><\/section>\n<p style=\"text-align: center;margin-bottom: 24px;\"><span style=\"font-size: 16px;letter-spacing: 1px;text-align: justify;text-indent: 0em;\"> <\/span><\/p>\n<p style=\"text-indent: 0px;margin-bottom: 0px;\"><span style=\"color: rgb(0, 122, 170);\"><strong><span style=\"color: rgb(0, 122, 170);letter-spacing: 0.578px;text-indent: 32px;text-wrap: wrap;background-color: rgb(255, 255, 255);font-size: 15px;\">\u5c0f\u679c\u8fd8<span style=\"color: rgb(0, 122, 170);background-color: rgb(255, 255, 255);font-size: 15px;letter-spacing: 0.578px;text-decoration: none solid rgba(0, 0, 0, 0.9);\">\u63d0\u4f9b\u601d\u8def\u8bbe\u8ba1\u3001\u5b9a\u5236\u751f\u4fe1\u5206\u6790\u3001\u6587\u732e\u601d\u8def\u590d\u73b0\uff1b\u6709\u9700\u8981\u7684\u5c0f\u4f19\u4f34\u6b22\u8fce\u76f4\u63a5\u626b\u7801\u54a8\u8be2\u5c0f\u679c\uff0c\u7aed\u8bda\u4e3a\u60a8\u7684\u79d1\u7814\u52a9\u529b\uff01<\/span><\/span><\/strong><\/span><\/p>\n<p style=\"margin-bottom: 0px;\"><br \/><\/p>\n<section style=\"font-size: 15px;padding-right: 2px;padding-left: 2px;margin-bottom: 0px;\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;flex: 0 0 auto;height: auto;border-color: rgb(114, 114, 114);border-width: 1px;border-style: solid;box-shadow: rgb(194, 209, 255) -5px 5px 0px;align-self: flex-start;\">\n<section style=\"justify-content: center;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 42.6829%;vertical-align: middle;box-shadow: rgb(43, 65, 110) 0px 0px 0px;flex: 0 0 auto;height: auto;padding-left: 10px;align-self: center;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;line-height: 0;transform: translate3d(20px, 0px, 0px);\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;width: 75%;height: auto;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-imgfileid=\"100018228\" data-ratio=\"1\" data-s=\"300,640\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_B2jkicacLzPjw4xMSqVvoucZjonVDA-42.jpg\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAxVYfSsM0wdf9d3RpNiaTcHohxPNEVs2VFhPMukpU8lchxrvcB2jkicacLzPjw4xMSqVvoucZjonVDA\/640?wx_fmt=jpeg'&from=appmsg\" data-type=\"jpeg\" data-w=\"430\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: 56.9106%;flex: 0 0 auto;height: auto;align-self: center;\">\n<section style=\"line-height: 2;letter-spacing: 1px;color: rgb(43, 65, 110);\" powered-by=\"xiumi.us\">\n<p style=\"margin-bottom: 2px;\"><strong>\u5b9a\u5236\u751f\u4fe1\u5206\u6790<\/strong><\/p>\n<p style=\"margin-bottom: 2px;\"><strong>\u670d\u52a1\u5668\u79df\u8d41<\/strong><\/p>\n<p><strong>\u626b\u7801\u54a8\u8be2\u5c0f\u679c<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247497780&idx=2&sn=7eee90af6f387e4153bba13028e545a1&chksm=cf7f68f1f808e1e7dfb3a0597ef442e5c6e700ecf6ee5a035c766a4c7486c12eabd0ab218ea6&scene=21#wechat_redirect\" textvalue=\"\u4f60\u5df2\u9009\u4e2d\u4e86\u6dfb\u52a0\u94fe\u63a5\u7684\u5185\u5bb9\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"1\" rel=\"noopener\"><span class=\"js_jump_icon h5_image_link\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-imgfileid=\"100018230\" data-ratio=\"0.3253333333333333\" data-s=\"300,640\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/16_7TvAyUibd1TPhJmZfialJtv6tu2SEg-14.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAxVYfSsM0wdf9d3RpNiaTcHoj9xlsoyiaBvzaezDUFAicibMAF8ts7TvAyUibd1TPhJmZfialJtv6tu2SEg\/640?wx_fmt=png&from=appmsg'\" data-type=\"png\" data-w=\"750\" style=\"vertical-align: middle;width: 100%;\" \/><\/span><\/a><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img js_insertlocalimg\" data-imgfileid=\"100018229\" data-ratio=\"0.3811111111111111\" data-s=\"300,640\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/17_9N02aBaau07RufXeXRLmvAHsrFZxtw-14.jpg\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAz5wg6Ne6sYkannSE9NiatkcPh3icbKanJagacjU6LqJrGAL29N02aBaau07RufXeXRLmvAHsrFZxtw\/640?wx_fmt=jpeg&from=appmsg'\" data-type=\"jpeg\" data-w=\"900\" style=\"letter-spacing: 0.578px;text-align: center;text-wrap: wrap;\" \/><\/section>\n<\/section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;text-align: left;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-end;padding-right: 2px;padding-left: 2px;\">\n<section style=\"margin: 10px 0% 2px;transform: translate3d(2px, 0px, 0px);\" powered-by=\"xiumi.us\">\n<section style=\"font-size: 16px;color: rgb(58, 66, 94);line-height: 1;letter-spacing: 5px;text-align: center;\">\n<p><strong>\u5f80\u671f\u56de\u987e<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"height: 3px;background-color: rgb(95, 156, 239);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<section style=\"margin-top: 2px;margin-right: 0%;margin-left: 0%;text-align: center;line-height: 0.8;font-size: 9px;\" powered-by=\"xiumi.us\">\n<section style=\"width: 0px;display: inline-block;border-top: 0.8em solid rgb(58, 66, 94);border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;flex: 100 100 0%;align-self: flex-end;height: auto;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"height: 3px;background-color: rgb(95, 156, 239);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<section style=\"margin-top: 2px;margin-right: 0%;margin-left: 0%;text-align: center;line-height: 0.8;font-size: 9px;\" powered-by=\"xiumi.us\">\n<section style=\"width: 0px;display: inline-block;border-top: 0.8em solid rgba(255, 255, 255, 0);border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"min-height: 40px;margin: 10px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"width: 100%;margin-right: auto;margin-bottom: -10px;margin-left: auto;\">\n<table width=\"100%\">\n<tbody>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:0\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:0.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>01<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247497780&idx=2&sn=7eee90af6f387e4153bba13028e545a1&chksm=cf7f68f1f808e1e7dfb3a0597ef442e5c6e700ecf6ee5a035c766a4c7486c12eabd0ab218ea6&scene=21#wechat_redirect\" textvalue=\"1024G\u5b58\u50a8\u7684\u751f\u4fe1\u670d\u52a1\u5668\uff0c\u4e24\u4eba\u6210\u56e2\uff0c1\u4eba\u514d\u5355\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">1024G\u5b58\u50a8\u7684\u751f\u4fe1\u670d\u52a1\u5668\uff0c\u4e24\u4eba\u6210\u56e2\uff0c1\u4eba\u514d\u5355\uff01<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:1\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:1.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>02<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247498878&idx=1&sn=fc34ed3f1d15d060bbaf8166adcebd58&chksm=cf7f6cbbf808e5ad0b5417e50ed75cfbd1b3a83ac43b97f1dfa718c822878a9a004990075133&scene=21#wechat_redirect\" textvalue=\"\u5355\u4e2a\u6570\u636e\u5e93\u7528\u817b\u4e86\uff1f\u591a\u6570\u636e\u5e93\u201c\u7ec4\u5408\u62f3\u201d\u5e26\u4f60\u6253\u5f00\u514d\u75ab\u6d78\u6da6\u65b0\u601d\u8def\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u5355\u4e2a\u6570\u636e\u5e93\u7528\u817b\u4e86\uff1f\u591a\u6570\u636e\u5e93\u201c\u7ec4\u5408\u62f3\u201d\u5e26\u4f60\u6253\u5f00\u514d\u75ab\u6d78\u6da6\u65b0\u601d\u8def\uff01<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:2\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:2.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>03<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247498673&idx=1&sn=1e09b74a836c1e64a62ae1f66eeb3f93&chksm=cf7f6b74f808e262de70be43fd73bf5fefdc0914e525eb2032f741a0152e619689cedc76946f&scene=21#wechat_redirect\" textvalue=\"\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u7684\u51c6\u5907\u5de5\u4f5c\uff0cGWAS\u6570\u636e\u7684\u7f51\u7ad9\u4e0b\u8f7d\u65b9\u6cd5\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"11\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u7684\u51c6\u5907\u5de5\u4f5c\uff0cGWAS\u6570\u636e\u7684\u7f51\u7ad9\u4e0b\u8f7d\u65b9\u6cd5<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:3\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:3.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: 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