{"id":55307,"date":"2024-06-16T16:24:57","date_gmt":"2024-06-16T08:24:57","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=55307"},"modified":"2024-06-16T16:24:57","modified_gmt":"2024-06-16T08:24:57","slug":"motif%e5%af%8c%e9%9b%86%e5%88%86%e6%9e%90%ef%bc%9fhomer%e5%8a%a9%e4%bd%a0%e4%b8%80%e8%87%82%e4%b9%8b%e5%8a%9b%ef%bc%81-2","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=55307","title":{"rendered":"motif\u5bcc\u96c6\u5206\u6790\uff1fHOMER\u52a9\u4f60\u4e00\u81c2\u4e4b\u529b\uff01"},"content":{"rendered":"


\n
\n<\/title><br \/>\n<meta charset=\"utf-8\"><br \/>\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,maximum-scale=1.0,user-scalable=0,viewport-fit=cover\"><\/p>\n<style>\n*{margin:0;padding:0}html{-ms-text-size-adjust:100%;-webkit-text-size-adjust:100%;line-height:1.6}img{z-index:999;position:relative;max-width:100%;margin:10px 0;}body{letter-spacing:.034em}h1,h2,h3,h4,h5,h6{font-weight:400;font-size:16px}a{color:#576b95;text-decoration:none;-webkit-tap-highlight-color:rgba(0,0,0,0)}td,th{word-wrap:break-word;padding:5px 10px;border:1px solid #DDD;}table{margin-bottom:10px;border-collapse:collapse;display:table;width:100%!important;}.appmsg_skin_default .rich_media_area_primary{background-color:#fff}.appmsg_skin_default .rich_media_area_primary .weui-loadmore_line .weui-loadmore__tips{background-color:#fff}.rich_media_area_primary{padding:20px 16px 12px;background-color:#fafafa}@media (max-width:375px){.rich_media_area_primary{padding:20px 60px 15px 60px}.rich_media_area_extra{padding:0 60px 21px 60px}}@media (min-width:1024px){.rich_media_area_primary_inner,.rich_media_area_extra_inner,body{max-width:677px;margin-left:auto;margin-right:auto}.rich_media_area_primary{padding-top:32px}}.rich_media{padding:20px;overflow:hidden;}.appmsg_skin_default .rich_media_area_primary{background-color:#fff}.appmsg_skin_default .rich_media_area_primary .weui-loadmore_line .weui-loadmore__tips{background-color:#fff}@media screen and (min-width:1024px){.rich_media_area_primary_inner,.rich_media_area_extra_inner{max-width:677px;margin-left:auto;margin-right:auto}.rich_media_area_primary{padding-top:32px}}.rich_media_content{overflow:hidden;color:#333;font-size:17px;word-wrap:break-word;-webkit-hyphens:auto;-ms-hyphens:auto;hyphens:auto;text-align:justify;position:relative;z-index:0}.rich_media_content *{max-width:100%!important;box-sizing:border-box!important;-webkit-box-sizing:border-box!important;word-wrap:break-word!important}.rich_media_content p{clear:both;min-height:1em}.rich_media_content em{font-style:italic}.rich_media_content fieldset{min-width:0}.rich_media_content .list-paddingleft-1,.rich_media_content .list-paddingleft-2,.rich_media_content .list-paddingleft-3{padding-left:2.2em}.rich_media_content .list-paddingleft-1 .list-paddingleft-2,.rich_media_content .list-paddingleft-2 .list-paddingleft-2,.rich_media_content .list-paddingleft-3 .list-paddingleft-2{padding-left:30px}.rich_media_content .list-paddingleft-1{padding-left:1.2em}.rich_media_content .list-paddingleft-3{padding-left:3.2em}.rich_media_content .code-snippet,.rich_media_content .code-snippet__fix{max-width:1000%!important}.rich_media_content .code-snippet *,.rich_media_content .code-snippet__fix *{max-width:1000%!important}.rich_media_title{font-size:22px;line-height:1.4;margin-bottom:13px;padding-bottom:13px;border-bottom:1px solid #e7e7eb;}@supports(-webkit-overflow-scrolling:touch){.rich_media_title{font-weight:700}}.rich_media_meta{display:inline-block;vertical-align:middle;padding:0 0 10px 0;font-size:15px;-webkit-tap-highlight-color:rgba(0,0,0,0)}.rich_media_meta.icon_appmsg_tag{margin-right:0px}.rich_media_meta.meta_tag_text{margin-right:0}.rich_media_meta_list em{font-style:normal}.rich_media_meta_text{color:#a5a5a5;}p{margin:0;}.msgBox{margin-top:20px;padding-top:20px;padding-left:50px;overflow:hidden;border-top:2px dashed #09a2ff;}.msg{padding-top:7px;clear:both;}.msgBody{float:right;width:100%;margin-left:55px;padding-bottom:15px;border-bottom:1px dashed #e0e0e0;}.userHeadImg{float:left;margin-left:-50px;}.userHeadImg img{width:40px;height:40px;margin-right:10px;border-radius:3px;}.userName{color:#888888;line-height:24px;font-size:14px;margin:5px 0 5px 0;height:24px;}.replyBody,.autherBody{color:#565656;font-size:15px;}.replyIcon{border-left:4px solid #33ab01;margin-right:5px;}.ad{text-decoration:none;color:#d6d4d4;font-size:12px;}.msgBodyReply{padding-top:5px;}.userName span{float:right;color:#afafaf;font-size:14px;}code{text-align:left;font-size:14px;display:block;white-space:pre;display:-webkit-box;display:-webkit-flex;display:flex;position:relative;}.code-snippet__fix{font-size:14px;margin:10px 0;display:block;color:#333;position:relative;background-color:rgba(0,0,0,0.03);border:1px solid #f0f0f0;border-radius:2px;display:-webkit-box;display:-webkit-flex;display:flex;padding-left:25px;line-height:26px}.code-snippet__fix code{text-align:left;font-size:14px;display:block;white-space:pre;display:-webkit-box;display:-webkit-flex;display:flex;position:relative;font-family:Consolas,\"Liberation Mono\",Menlo,Courier,monospace}.code-snippet__comment,.code-snippet__quote{color:#afafaf;font-style:italic}.code-snippet__keyword,.code-snippet__selector-tag,.code-snippet__subst{color:#ca7d37}.code-snippet__number,.code-snippet__literal,.code-snippet__variable,.code-snippet__template-variable,.code-snippet__tag .code-snippet__attr{color:#0e9ce5}.code-snippet__string,.code-snippet__doctag{color:#d14}.code-snippet__title,.code-snippet__section,.code-snippet__selector-id{color:#d14}.code-snippet__subst{font-weight:normal}.code-snippet__type,.code-snippet__class .code-snippet__title{color:#0e9ce5}.code-snippet__tag,.code-snippet__name,.code-snippet__attribute{color:#0e9ce5;font-weight:normal}.code-snippet__regexp,.code-snippet__link{color:#ca7d37}.code-snippet__symbol,.code-snippet__bullet{color:#d14}.code-snippet__built_in,.code-snippet__builtin-name{color:#ca7d37}.code-snippet__meta{color:#afafaf}.code-snippet__deletion{background:#fdd}.code-snippet__addition{background:#dfd}.code-snippet__emphasis{font-style:italic}.code-snippet__strong{font-weight:bold}.account_avatar{width:40px;height:40px;padding:0;}.account_info{display:-webkit-box;display:-webkit-flex;display:flex;-webkit-box-align:center;-webkit-align-items:center;padding:20px 0;align-items:center}.flex_bd{padding-left:14px;}.account_nickname{display:inline-block;vertical-align:middle;line-height:1.2;color:#576b95;font-size:14px}.account_desc{overflow:hidden;text-overflow:ellipsis;display:-webkit-box;-webkit-box-orient:vertical;-webkit-line-clamp:1;color:rgba(0,0,0,0.3);font-size:14px;line-height:1.2;padding-top:.4em}.msg_source_url{text-align:left;word-break:break-all;margin-top:20px;}.msg_source_url a{padding-right:10px;}.msg_source_url .url_text{color:#a8a8a8;}.video-desc{font-size:14px;margin-top:15px;color:#6c6c6c;}.msg_source_url{text-align:left;}.original_primary_card_tips{color:rgba(0,0,0,0.3);line-height:1.4;font-size:15px;}.weui-flex__item{margin-bottom:20px;padding:20px 16px;margin-top:16px;line-height:1.4;align-items:center;background-color:#f7f7f7;border-radius:8px;position:relative;}.original_primary_desc{color:rgba(0,0,0,0.5);font-size:14px;padding-top:4px;width:auto;overflow:hidden;text-overflow:ellipsis;}.msgBodyReplyList{border-top:1px solid #e1e1e1;margin-top:10px;}.msgBodyReplyListTop{border-top:0;}.reply_like_num{float:right;font-size:14px;color:#c7c7c7;}.msgData{margin-top:20px;color:#626262;}.msgData span{font-size:14px;padding-right:15px;}.msgData .likes{float:right;padding-right:0;}.js_text_content p{font-size:18px;}.rich_media_meta_link{font-size:15px;}blockquote {padding-left: 10px;border-left: 3px solid #dbdbdb;color: rgba(0,0,0,0.5);font-size: 15px;padding-top: 4px;margin: 1em 0;}.video_iframe{width:500px;height:400px;}.blockquote_info{color:#b5b5b5;margin-top:10px;}#copyright_logo{color:#bdbdbd;}.rich_media_meta_list{margin-bottom:10px;}.reprint{background:#efefef;border-radius:5px;padding:8px;color:#1f1f1f;}.reprint a{word-break:break-all;}.topic{color:#8e8e8e;background:#f7f7f7;border-radius:5px;padding:10px 8px;}.topic a{padding-right:5px;}.topic p{margin-bottom:5px;}\n<\/style>\n<link href=\"https:\/\/www.juyifx.cn\/config\/css\/wxArticle.css\" rel=\"stylesheet\"\/>\n<\/head><script>\nvar data={\"mp\":\"\u751f\u4fe1\u679c\",\"title\":\"motif\u5bcc\u96c6\u5206\u6790\uff1fHOMER\u52a9\u4f60\u4e00\u81c2\u4e4b\u529b\uff01\",\"time\":\"2023-07-20 19:03:27\",\"timeStamp\":\"1689851007\"};\n<\/script><br \/>\n<body><\/p>\n<div class=\"rich_media\">\n<h1 class=\"rich_media_title\" id=\"activity-name\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247490465&idx=3&sn=b0c194093f427d116014e575204168c6&chksm=cf7c8b64f80b027268eadc49f8684423e7eaf40fc1830beab1aff7388c7503fdbee925c12837#rd\" target=\"_blank\" rel=\"noopener\">motif\u5bcc\u96c6\u5206\u6790\uff1fHOMER\u52a9\u4f60\u4e00\u81c2\u4e4b\u529b\uff01<\/a><\/h1>\n<div id=\"meta_content\" class=\"rich_media_meta_list\"><span class=\"rich_media_meta rich_media_meta_text\">\u5c0f\u56fe  <\/span><span class=\"rich_media_meta rich_media_meta_nickname\" id=\"profileBt\"><a href=\"javascript:void(0);\" class=\"wx_tap_link js_wx_tap_highlight weui-wa-hotarea\" id=\"js_name\">\u751f\u4fe1\u679c  <\/a><\/span><em id=\"publish_time\" class=\"rich_media_meta rich_media_meta_text\">2023-07-20 19:03:27<\/em><\/div>\n<p><content><\/p>\n<div class=\"reprint\">\n<p>\u8f6c\u81ea\u516c\u4f17\u53f7\uff1a\u751f\u4fe1\u56fe<br \/><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247483818&idx=1&sn=e143e182b8561e74216a06ea9d73ca34\" target=\"_blank\" title=\"\u9605\u8bfb\u539f\u6587\" rel=\"noopener\">http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247483818&idx=1&sn=e143e182b8561e74216a06ea9d73ca34<\/a><\/p>\n<\/div>\n<section style=\"font-size: 16px;margin-bottom: 24px;\">\n<section style=\"display: flex;flex-flow: row nowrap;margin: 10px 0%;text-align: left;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: bottom;width: 50%;background-color: rgb(242, 183, 183);margin-right: 3px;flex: 0 0 auto;align-self: flex-end;height: auto;padding: 3px 10px;\">\n<section style=\"font-size: 17px;color: rgb(255, 255, 255);text-align: right;letter-spacing: 4px;\" powered-by=\"xiumi.us\">\n<p><strong>\u70b9\u51fb\u84dd\u5b57<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;border-left: 4px solid rgb(242, 183, 183);border-bottom-left-radius: 0px;flex: 100 100 0%;align-self: stretch;height: auto;padding: 3px 10px;background-color: rgba(254, 245, 240, 0.8);\">\n<section style=\"color: rgb(181, 126, 121);font-size: 17px;letter-spacing: 4px;\" powered-by=\"xiumi.us\">\n<p><strong>\u5173\u6ce8\u5c0f\u56fe<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u5927\u5bb6\u597d\uff0c\u5c0f\u56fe\u53c8\u6765\u5566\uff0c\u5927\u5bb6\u8fd8\u8bb0\u5f97motif\u662f\u4ec0\u4e48\u5417\uff1f\u601d\u8003\u4e09\u79d2\u949f\uff0c\u5982\u679c\u4f60\u8fd8\u8bb0\u5f97\u7684\u8bdd\uff0c\u90a3\u5c0f\u56fe\u7ed9\u4f60\u5927\u62c7\u54e5\uff01<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">\u4e0b\u9762\u5c0f\u56fe\u7ed9\u5927\u5bb6\u8be6\u7ec6\u4ecb\u7ecd\u4e0bmotif\uff1amotif\u662f\u6307\u4e00\u6bb5\u5177\u6709\u7279\u5b9a\u529f\u80fd\u6216\u7ed3\u6784\u7684\u5206\u5b50\u5e8f\u5217\u6216\u5143\u7d20\uff0c\u901a\u5e38\u662f\u4fdd\u5b88\u7684\u3001\u91cd\u590d\u7684\u3001\u4e0e\u5176\u4ed6\u5206\u5b50\u76f8\u4e92\u4f5c\u7528\u7684\u3002Motif\u53ef\u4ee5\u5b58\u5728\u4e8eDNA\u3001RNA\u6216\u86cb\u767d\u8d28\u4e2d\uff0c\u4f8b\u5982\u8f6c\u5f55\u56e0\u5b50\u7684\u7ed3\u5408\u4f4d\u70b9\u3001RNA\u9176\u7684\u6d3b\u6027\u4e2d\u5fc3\u3001\u86cb\u767d\u8d28\u7684\u7ed3\u6784\u57df\u7b49\u3002Motif\u53ef\u4ee5\u7528\u5e8f\u5217logo\u56fe\u3001\u4e00\u81f4\u6027\u5e8f\u5217\u6216PFM\u77e9\u9635\u7b49\u65b9\u5f0f\u6765\u8868\u793a\u548c\u5206\u6790\u3002Motif\u7684\u7814\u7a76\u53ef\u4ee5\u5e2e\u52a9\u6211\u4eec\u7406\u89e3\u57fa\u56e0\u8c03\u63a7\u3001\u5206\u5b50\u8fdb\u5316\u3001\u529f\u80fd\u9884\u6d4b\u7b49\u751f\u7269\u5b66\u95ee\u9898\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">\u5e8f\u5217\u57fa\u5e8f\u5728\u57fa\u56e0\u8c03\u63a7\u5206\u6790\u4e2d\u8d8a\u6765\u8d8a\u91cd\u8981\u3002Motif\u5e76\u4e0d\u5c40\u9650\u4e8e\u57fa\u56e0\u7ec4DNA\u5e8f\u5217\u8fd8\u662fRNA\u5e8f\u5217\uff0c\u751a\u81f3\u86cb\u767d\u8d28\u5e8f\u5217\u4e5f\u53ef\u4ee5\u63d0\u53d6\u51fa\u76f8\u5e94\u7684motif\u3002\u5f53\u67d0\u4e00\u4e2a\u5927\u7c7b\u7684\u5e8f\u5217\u4e2d\uff0c\u5927\u91cf\u91cd\u590d\u51fa\u73b0\u76f8\u540c\u7684\u5e8f\u5217\u7ed3\u6784\u7684\u65f6\u5019\uff0c\u5c31\u5b58\u5728\u63a2\u7d22\u5b83\u610f\u4e49\u7684\u4ef7\u503c\u3002\u57fa\u4e8emotif\u5e8f\u5217\u7684\u63d0\u53d6\uff0c\u6211\u4eec\u53ef\u4ee5\u9884\u6d4b\u6f5c\u5728\u7684\u7ed3\u5408\u4f4d\u70b9\u7b49\u7b49\uff0c\u6709\u52a9\u4e8e\u6211\u4eec\u8fdb\u4e00\u6b65\u7406\u89e3\u5404\u751f\u7269\u5b66\u8fc7\u7a0b\u4e2d\u6d89\u53ca\u7684\u751f\u7269\u5b66\u610f\u4e49\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">\u770b\u5230\u8fd9\uff0c\u5927\u5bb6\u662f\u4e0d\u662f\u5bf9motif\u5145\u6ee1\u4e86\u597d\u5947\u5462<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">\u5927\u5bb6\u7ecf\u5e38\u770b\u5230\u7684motif\u7684logo\u56fe\u5982\u4e0b\u56fe\u6240\u793a<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.19267139479905437\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-07-20_\u300c\u8f6c\u300dmotif\u5bcc\u96c6\u5206\u6790\uff1fHOMER\u52a9\u4f60\u4e00\u81c2\u4e4b\u529b\uff01\/1_y3N5w7v2MeVpekZSuty5UZRVXa5QSg.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qt9b8V9u7Oj4VwUqApWia4oCoMTH55zDR5D0AevIKumyRARey3N5w7v2MeVpekZSuty5UZRVXa5QSg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"846\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\">\u90a3\u600e\u4e48\u53bb\u7406\u89e3motif\u7684logo\u56fe\u5462\uff1f\u5c0f\u56fe\u6765\u544a\u8bc9\u5927\u5bb6\uff1amotif\u7684logo\u56fe\u7ecf\u5e38\u7528\u4e8e\u63cf\u8ff0\u5e8f\u5217\u7279\u5f81\uff0c\u5982DNA\u4e2d\u7684\u86cb\u767d\u8d28\u7ed3\u5408\u4f4d\u70b9\u7b49\u3002motif\u7684logo\u56fe\u7531\u6bcf\u4e2a\u4f4d\u7f6e\u7684\u4e00\u5806\u5b57\u6bcd\u7ec4\u6210\u3002\u5b57\u6bcd\u7684\u76f8\u5bf9\u5927\u5c0f\u8868\u793a\u5b83\u4eec\u5728\u5e8f\u5217\u4e2d\u7684\u9891\u7387\u3002\u5b57\u6bcd\u9ad8\u7684\u5c31\u8bf4\u660e\u8be5\u4f4d\u7f6e\u51fa\u73b0\u8fd9\u4e2a\u78b1\u57fa\u7684\u9891\u7387\u66f4\u5927\u3002<\/p>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.3;text-align: justify;letter-spacing: 1px;\">\n<p style=\"white-space: normal;\"><strong>\u90a3\u4e48\u5982\u4f55\u4f7f\u7528homer\u53bb\u9884\u6d4bmotif\u5462\uff1f\u4e0b\u9762\u5c0f\u56fe\u5e26\u5927\u5bb6\u4e00\u63a2\u7a76\u7adf<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"text-indent: 0em;white-space: normal;\">\u9996\u5148\u8bf4\u4e00\u4e0b\u7528\u5230\u7684\u8f6f\u4ef6HOMER\uff0cHOMER \u662f\u4e00\u5957\u7528\u4e8eMotif\u67e5\u627e\u548c\u4e8c\u4ee3\u6570\u636e\u5206\u6790\u7684\u5de5\u5177\u3002HOMER \u4e2d\u7684\u5de5\u5177\u662f\u4f7f\u7528Perl \u548cC++\u7f16\u5199\u7684\uff0c\u662fLinux command line based\u3002HOMER \u8fd9\u4e2a\u8f6f\u4ef6\u662f\u4e00\u4e2a\u5927\u6742\u70e9\uff0c\u80fd\u89e3\u51b3\u51e0\u4e4e\u6240\u6709\u7684\u9ad8\u901a\u91cf\u6d4b\u5e8f\u6570\u636e\u7684\u5206\u6790\u3002<\/p>\n<p style=\"text-indent: 0em;white-space: normal;\"><br \/><\/p>\n<p style=\"text-indent: 0em;white-space: normal;\"><strong>HOMER \u4e00\u4e2a\u5e38\u7528\u7684motif\u5206\u6790\u8f6f\u4ef6\u3002<\/strong>\u5b83\u901a\u8fc7\u6bd4\u8f83\u4e24\u4e2a\u5e8f\u5217\u96c6\uff0c\u5e76\u4f7f\u7528ZOOPS scoring\u548c\u8d85\u51e0\u4f55\u5206\u5e03\uff08\u6216\u8005\u8d1f\u4e8c\u9879\u5206\u5e03\uff09\u8fdb\u884cmotif\u7684\u5bcc\u96c6\u5206\u6790\u3002\u5b83\u4e3b\u8981\u7528\u4e8eChIP-seq\u548cATAC-seq\u548cpromoter\u5206\u6790\uff0c\u4f46\u4e5f\u53ef\u4ee5\u7528\u4e8e\u6838\u9178\u5e8f\u5217\u7684motif\u5206\u6790\u95ee\u9898\u3002<\/p>\n<p style=\"text-indent: 0em;white-space: normal;\"><br \/><\/p>\n<p style=\"text-indent: 0em;white-space: normal;\"><strong>HOMER\u8f6f\u4ef6\u53ef\u4ee5\u8fdb\u884c\u591a\u79cd\u7c7b\u578b\u7684motif\u5206\u6790<\/strong>\uff0c\u5982 promoter motif analysis \uff0c\u57fa\u56e0\u7ec4\u4f4d\u7f6emotif\u5206\u6790(ChIP-seq\u5206\u6790\u4e2d\u7684motif\u5206\u6790)\uff0c\u5229\u7528\u81ea\u5b9a\u4e49\u7684fasta\u6587\u4ef6\u8fdb\u884cmotif\u5206\u6790\uff0cRNA\u5e8f\u5217\u7684motif\u5206\u6790\uff08\u5206\u6790CLIP-seq\u6570\u636e\u4e2d\u7684RNA binding elements\uff09\u3002<\/p>\n<p style=\"text-indent: 0em;white-space: normal;\"><br \/><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><strong>\u8fd9\u662fHOMER\u8f6f\u4ef6\u7684\u5b98\u7f51\u5730\u5740\uff1a<\/strong><\/p>\n<p style=\"white-space: normal;\">http:\/\/homer.ucsd.edu\/homer\/ngs\/peakMotifs.html<\/p>\n<p style=\"white-space: normal;\">\u5927\u5bb6\u4e00\u5b9a\u8981\u517b\u6210\u591a\u770b\u5b98\u65b9\u6587\u6863\u7684\u597d\u4e60\u60ef\u55f7<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\"><strong>HOMER\u7684\u5b89\u88c5\u53ef\u4ee5\u4f7f\u7528conda\u6765\u5b8c\u6210\uff1a<\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">conda install -c bioconda homer<\/span><\/code><\/pre>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><strong>\u4e0b\u9762\u9700\u8981configureHomer.pl\u5b8c\u6210Homer\u8f6f\u4ef6\u7684\u914d\u7f6e\uff1a<\/strong><\/p>\n<p style=\"text-indent: 2em;white-space: normal;\" powered-by=\"xiumi.us\">1.\u5148\u4e0b\u8f7dconfigureHomer.pl\uff1a<\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">wget http:<span class=\"code-snippet__comment\">\/\/homer.ucsd.edu\/homer\/configureHomer.pl<\/span><\/span><\/code><\/pre>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<p style=\"text-indent: 2em;white-space: normal;\" powered-by=\"xiumi.us\">2.\u4f7f\u7528configureHomer.pl\u914d\u7f6eHomer\uff08\u5c0f\u4f19\u4f34\u4eec\u6ce8\u610f\u6587\u4ef6\u8def\u5f84\u95ee\u9898\u55f7\uff09<\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">perl configureHomer.pl  [options]  <\/span><\/code><\/pre>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\">\u5927\u5bb6\u53ef\u4ee5\u4f7f\u7528configureHomer.pl\u6765\u914d\u7f6eHomer\uff0c\u4f8b\u5982\u4e0b\u8f7d\u4eba\u7c7b\uff0c\u5c0f\u9f20\u7684\u53c2\u8003\u57fa\u56e0\u7ec4\u7b49\uff0c\u4eba\u548c\u5c0f\u9f20\u7684\u7814\u7a76\u5c45\u591a\uff0c\u8fd9\u91cc\u53ea\u4ee5\u8fd9\u4e24\u8005\u4e3e\u4f8b<\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#  \u4e0b\u8f7d hg19 \u4eba\u7684\u53c2\u8003\u57fa\u56e0\u7ec4\uff0c\u5c06hg19\u66ff\u6362\u4e3amm10\u53ef\u4e0b\u8f7dmm10 \u5c0f\u9f20\u7684\u53c2\u8003\u57fa\u56e0\u7ec4<\/span><\/code><code><span class=\"code-snippet_outer\">perl configureHomer.pl -install hg19<\/span><\/code><\/pre>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.3;text-align: justify;letter-spacing: 1px;\">\n<p style=\"white-space: normal;\"><strong>\u4e0d\u8fc7\u8fd9\u91cc\u5c0f\u679c\u7814\u7a76\u7684\u662f\u975e\u6a21\u5f0f\u751f\u7269\uff0c\u90a3\u4e48\u5c0f\u679c\u5c31\u5e26\u5927\u5bb6\u4e00\u8d77\u7528\u53ef\u7231\u7684\u5bb6\u8695\u6765\u5b66\u4e60HOMER\u8f6f\u4ef6\u5427<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\">\u9996\u5148\u5c0f\u679c\u770b\u7f51\u4e0a\u5c0f\u4f19\u4f34\u8bf4\u4f7f\u7528\u672c\u5730\u7684\u53c2\u770b\u57fa\u56e0\u7ec4\u76f4\u63a5\u547d\u4ee4\u884c\u4f7f\u7528\u5c31\u884c\uff0c\u53ef\u628a\u5c0f\u679c\u5bb3\u82e6\u4e86\uff0c\u4e00\u76f4error\uff01\u4e0d\u8fc7\u4e0d\u614c\uff0c\u5c0f\u679cdebug\u662f\u6700\u5f3a\u7684\uff0c\u5c0f\u679c\u53c8\u67e5\u5230\u662f\u56e0\u4e3a\u53c2\u8003\u57fa\u56e0\u7ec4\u7684\u95ee\u9898\uff0c\u770b\u4e86\u770bhomer\u7684\u7248\u672c\uff1a<\/p>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.0838150289017341\" data-s=\"300,640\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_KbhMy50rkZJZpg4L6ubpltNR3NhLbA.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qt9b8V9u7Oj4VwUqApWia4oCia0lyNXM4FDEkXVwF9prsSl1NKbhMy50rkZJZpg4L6ubpltNR3NhLbA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"692\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u5c0f\u56fe\u901a\u8fc7\u67e5\u9605\u5b98\u7f51\u53d1\u73b0\u4ecehomer v4.4 \u5f00\u59cb\u5c31\u53ef\u4ee5\u81ea\u5b9a\u4e49homer\u4e86\uff0c\u6240\u4ee5\u6211\u4eec\u9700\u8981\u4f7f\u7528loadGenome.pl\u6216loadPromoters.pl\u547d\u4ee4\u521b\u5efa\u81ea\u5df1\u7684\u57fa\u56e0\u7ec4\u548c\u542f\u52a8\u5b50 FASTA \u6216\u6ce8\u91ca\u6587\u4ef6<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\"><strong>\u67e5\u9605\u5e2e\u52a9\u6587\u6863\u53d1\u73b0\uff1a<\/strong><\/p>\n<p style=\"white-space: normal;\">Required Parameters:<\/p>\n<p style=\"white-space: normal;\">      -name(i.e. hg19, tair10, etc.)<\/p>\n<p style=\"white-space: normal;text-align: left;\"><span style=\"letter-spacing: 0.034em;\">      <\/span><span style=\"letter-spacing: 0.034em;\">-fasta(Single genome sequence, preferrabley soft masked, unzipped)<\/span><\/p>\n<p style=\"white-space: normal;text-align: left;\">      -gtf(Transcript annotation in gtf format, -gff\/-gff3 to use them)<\/p>\n<p style=\"white-space: normal;\">      -org<\/p>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">\u6240\u4ee5\u6211\u4eec\u9700\u8981\u53c2\u8003\u57fa\u56e0\u7ec4fasta\u6587\u4ef6\u548cgtf\u6587\u4ef6<\/p>\n<p style=\"white-space: normal;\"><strong>\u4e0b\u9762\u662f\u5c0f\u56fe\u7684\u4ee3\u7801\uff1a<\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">loadGenome.pl -gtf  test.gtf  -name  test  -fasta  test_assembly.fa  -org null<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">\u4e0b\u9762\u5c31\u662f\u9884\u6d4bmotif\u7684\u8fc7\u7a0b\u4e86\uff0c\u4ee5CHIP-seq\u6d41\u7a0b\u4e3a\u4f8b\uff0c\u8f93\u5165\u6587\u4ef6\u53ef\u4ee5\u662fMACS2\u8f6f\u4ef6callpeak\u7684bed\u6587\u4ef6(\u53ef\u4ee5\u76f4\u63a5\u4f7f\u7528)\u6216\u8005\u662fHOMER\u8f6f\u4ef6\u6307\u5b9a\u7684peak\u6587\u4ef6\u683c\u5f0f\u3002peak\u6587\u4ef6\u683c\u5f0f\uff1a\u4f7f\u7528Tab\u5206\u9694\uff0c\u5171\u4e94\u5217\uff0c\u5206\u522b\u662f peak ID , chr , start , end ,strand<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\"><strong>\u4e0b\u9762\u662f\u5c0f\u56fe\u7684\u4ee3\u7801\uff1a<\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">findMotifsGenome.pl  test.bed  test  sample_motif_dir  -len <span class=\"code-snippet__number\">8<\/span>,<span class=\"code-snippet__number\">10<\/span>,<span class=\"code-snippet__number\">12<\/span><\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">\u53c2\u6570\u7684\u89e3\u91ca\u5982\u4e0b\uff1a<\/p>\n<p style=\"white-space: normal;\">test.bed \uff1abed\u683c\u5f0f\u6587\u4ef6<\/p>\n<p style=\"white-space: normal;\">test \uff1a\u81ea\u5b9a\u4e49\u7684\u53c2\u8003\u57fa\u56e0\u7ec4\uff08loadGenome.pl\u547d\u4ee4\u4e2d\u7684name\u53c2\u6570\uff09<\/p>\n<p style=\"white-space: normal;\">sample_motif_dir \uff1a\u8f93\u51fa\u6587\u4ef6\u5939<\/p>\n<p style=\"white-space: normal;\">-len \uff1amotif\u7684\u957f\u5ea6\uff0c\u9ed8\u8ba48\uff0c10\uff0c12\uff0c\u8d8a\u5927\u8d8a\u6d88\u8017\u8ba1\u7b97\u8d44\u6e90<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">HOMER\u7684\u8f93\u51fa\u7ed3\u679c\u4e2d\u6709\u540d\u4e3ahomerResults.html\u7684\u7f51\u9875\u6587\u4ef6\uff0c\u5728\u91cc\u9762\u53ef\u4ee5\u8be6\u7ec6\u7684\u770b\u5230motif\u7684\u7ed3\u679c\uff0c\u4e0b\u9762\u662f\u5c0f\u679c\u7684\u7ed3\u679c<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.42407407407407405\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-07-20_\u300c\u8f6c\u300dmotif\u5bcc\u96c6\u5206\u6790\uff1fHOMER\u52a9\u4f60\u4e00\u81c2\u4e4b\u529b\uff01\/3_w8kD2r8lpD89QBGxL9ft5RN3W0rqLg.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0Qt9b8V9u7Oj4VwUqApWia4oCACxXrgldCiaUGDjqzUtssvojfw8kD2r8lpD89QBGxL9ft5RN3W0rqLg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\">\u8f93\u51fa\u7ed3\u679c\u6309\u7167p-value\u6392\u5e8f\uff0c\u6700\u540e\u4e00\u5217\u662f\u4e00\u4e2a\u94fe\u63a5\u5230motif\u6587\u4ef6\u7684\u8d85\u94fe\u63a5\uff0c\u53ef\u4ee5\u4ece\u8fd9\u4e2a\u6587\u4ef6\u4e2d\u627e\u5230\u5305\u542b\u6b64motif\u7684\u5176\u4ed6\u5e8f\u5217\u3002\u5728Best Match\/Details \u5217\u4e2d\uff0cHOMER\u5c55\u793a\u4e0edenovo motif\u6700\u5339\u914d\u7684\u5df2\u77e5motif\u3002<\/p>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;margin-bottom: 10px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(176, 176, 176);padding: 7px;\">\n<section style=\"justify-content: flex-start;display: flex;flex-flow: row nowrap;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgba(249, 238, 237, 0.5);padding: 18px;\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"text-align: justify;font-size: 14px;\">\n<p style=\"white-space: normal;\">\u4eca\u5929\u7684\u5173\u4e8ehomer\u9884\u6d4bmotif\u7684\u5b66\u4e60\u5c31\u5230\u8fd9\u91cc\u5566\uff0c\u611f\u5174\u8da3\u7684\u5c0f\u4f19\u4f34\u53ef\u4ee5\u627e\u5c0f\u56fe\u8ba8\u8bba\uff0c\u6709\u611f\u89c9\u751f\u4fe1\u5206\u6790\u590d\u6742\u7684\u5c0f\u4f19\u4f34\u53ef\u4ee5\u76f4\u63a5\u4f7f\u7528\u6211\u4eec\u7684\u751f\u4fe1\u5c0f\u5de5\u5177\u54e6\uff0c\u6211\u4eec\u660e\u5929\u89c1\u54af~<\/p>\n<p style=\"white-space: normal;\">\u6b22\u8fce\u4f7f\u7528\uff1a\u4e91\u751f\u4fe1\u5e73\u53f0 ( http:\/\/www.biocloudservice.com\/home.html)<\/p>\n<\/section>\n<\/section>\n<section style=\"transform: scale(0.5);transform-origin: center center;margin-top: -65px;margin-bottom: -65px;\" powered-by=\"xiumi.us\">\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"1\" data-s=\"300,640\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_HJKUXsPfO5mnyOps5LngRTI7sIRCxg.jpg\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0Qt9b8V9u7Oj4VwUqApWia4oCsglOwerpGz1VJLE0iaHPCicjOEHJKUXsPfO5mnyOps5LngRTI7sIRCxg\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"258\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"min-height: 40px;margin: 10px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"width: 100%;margin-right: auto;margin-bottom: -10px;margin-left: auto;\">\n<table width=\"100%\">\n<tbody>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:33.classicTable1:0\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:33.classicTable1:0.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;background-color: rgb(249, 174, 165);padding: 10px 0px;\" width=\"96.3700%\">\n<section style=\"line-height: 1;text-align: center;font-size: 17px;color: rgb(255, 255, 255);letter-spacing: 5px;\" powered-by=\"xiumi.us\">\n<p><strong>\u5f80\u671f\u63a8\u8350<\/strong><\/p>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:33.classicTable1:1\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:33.classicTable1:1.td@@0\" style=\"border-top: 0px none rgb(62, 62, 62);border-right: 0px none rgb(62, 62, 62);border-left: 0px none rgb(62, 62, 62);border-bottom-color: rgb(202, 198, 198);border-bottom-style: dashed;background-color: rgb(247, 247, 247);padding-right: 5px;padding-left: 5px;\" width=\"96.3700%\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row nowrap;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: middle;border-width: 0px;align-self: center;flex: 0 0 auto;\">\n<p powered-by=\"xiumi.us\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247483794&idx=1&sn=f11f897a95432581180e0f9d3f378a0a&chksm=c1b17c6ff6c6f5791abdffbb2df655cffbc0dd94f89d991fe72ebf4c5077cf0d17940ed4e2c0&scene=21#wechat_redirect\" textvalue=\"\u4e09\u5206\u949f\uff01HiC-Pro\u5e26\u4f60\u8dd1\u5b8cHi-C\u5206\u6790\u6d41\u7a0b\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u4e09\u5206\u949f\uff01HiC-Pro\u5e26\u4f60\u8dd1\u5b8cHi-C\u5206\u6790\u6d41\u7a0b<\/a><\/p>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:33.classicTable1:2\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:33.classicTable1:2.td@@0\" style=\"border-top: 0px none rgb(62, 62, 62);border-right: 0px none rgb(62, 62, 62);border-left: 0px none rgb(62, 62, 62);border-bottom-color: rgb(202, 198, 198);border-bottom-style: dashed;background-color: rgb(247, 247, 247);padding-right: 5px;padding-left: 5px;\" width=\"96.3700%\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row nowrap;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: middle;border-width: 0px;align-self: center;flex: 0 0 auto;\">\n<p powered-by=\"xiumi.us\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247483793&idx=1&sn=65ac6e87445da135369aa440ca4fc0f6&chksm=c1b17c6cf6c6f57a3cfc4ba40e2e9897662acfc975f14944eafb1edea17428eca54543a95881&scene=21#wechat_redirect\" textvalue=\"\u3010\u4e00\u6587\u4e00\u5206\u949f\u3011\u5e26\u4f60\u8bfb\u61c2WGCNA\u7ed3\u679c\u56fe\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u3010\u4e00\u6587\u4e00\u5206\u949f\u3011\u5e26\u4f60\u8bfb\u61c2WGCNA\u7ed3\u679c\u56fe<\/a><\/p>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:33.classicTable1:3\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:33.classicTable1:3.td@@0\" style=\"border-top: 0px none rgb(62, 62, 62);border-right: 0px none rgb(62, 62, 62);border-left: 0px none rgb(62, 62, 62);border-bottom-color: rgb(202, 198, 198);border-bottom-style: dashed;background-color: rgb(247, 247, 247);padding-right: 5px;padding-left: 5px;\" width=\"96.3700%\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row nowrap;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: middle;border-width: 0px;align-self: center;flex: 0 0 auto;\">\n<p powered-by=\"xiumi.us\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247483800&idx=1&sn=b82aed68eb44d338c919441a94ae79fd&chksm=c1b17c65f6c6f57345b118f7e21b516e4bb32f160eab05420d5cdfa0a898293635a13b14dcaf&scene=21#wechat_redirect\" textvalue=\"\u82b1\u4e09\u5206\u949f\uff0c\u8ba9\u4f60\u5bf9XPCLR\u4e86\u5982\u6307\u638c\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u82b1\u4e09\u5206\u949f\uff0c\u8ba9\u4f60\u5bf9XPCLR\u4e86\u5982\u6307\u638c<\/a><\/p>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\">\ud83d\udc47\u70b9\u51fb\u9605\u8bfb\u539f\u6587\u8fdb\u5165\u7f51\u5740<\/p>\n<\/section>\n<p style=\"display: none;margin-bottom: 24px;\"><mp-style-type data-value=\"3\"><\/mp-style-type><\/p>\n<div class=\"msg_source_url\"><a href=\"http:\/\/www.biocloudservice.com\/home.html\" target=\"_blank\" rel=\"noopener\">\u9605\u8bfb\u539f\u6587<\/a><\/div>\n<p><\/content><\/p>\n<div class=\"msg_source_url\"><a href=\"http:\/\/www.biocloudservice.com\/home.html\" target=\"_blank\" rel=\"noopener\">\u9605\u8bfb\u539f\u6587<\/a><\/div>\n<\/div>\n<p><\/body><br \/>\n<\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>motif\u5bcc\u96c6\u5206\u6790\uff1fHOMER\u52a9\u4f60\u4e00\u81c2\u4e4b\u529b\uff01 \u5c0f\u56fe  \u751f\u4fe1\u679c  202 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/55307"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=55307"}],"version-history":[{"count":1,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/55307\/revisions"}],"predecessor-version":[{"id":55312,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/55307\/revisions\/55312"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=55307"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=55307"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=55307"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}