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16px;\">\u4f5c\u8005\u89c2\u5bdf\u5230\u80a0\u9053\u83cc\u4e0e\u7cbe\u795e\u75be\u75c5\u662f\u6709\u76f8\u5173\u6027\u7684\uff0c\u4f46\u662f\u76f4\u63a5\u7814\u7a76\u9700\u8981\u5927\u91cf\u7684\u4eba\u529b\u7269\u529b\uff0c\u6240\u4ee5\u9700\u8981\u5bfb\u627e\u4e00\u4e2a\u66ff\u4ee3\u5de5\u5177\u3002\u4eba\u5728\u51fa\u751f\u7684\u65f6\u5019\u4f1a\u6709\u5927\u91cf\u7684\u9057\u4f20\u53d8\u5f02\uff0c\u8fd9\u4e9b\u9057\u4f20\u53d8\u5f02\u4e0d\u4f1a\u53d7\u5176\u4ed6\u56e0\u7d20\u5f71\u54cd\uff0c\u4f5c\u8005\u4ece\u4eba\u7c7b\u57fa\u56e0\u7ec4\u4e0e\u80a0\u9053\u83cc\u7fa4\u6570\u636e\u5e93mbGWAS\u4e2d\u627e\u5230\u4e0e\u80a0\u9053\u83cc\u7fa4\u7279\u5f81\u5f3a\u76f8\u5173\u7684\u9057\u4f20\u53d8\u5f02\uff08SNP\uff09\uff0c\u4f46\u662f\u8fd9\u4e9bSNP\u4e0e\u5f71\u54cd\u7cbe\u795e\u75c5\u7684\u5176\u4ed6\u6df7\u6742\u56e0\u7d20\u65e0\u5173\uff0c\u4e0e\u7cbe\u795e\u75c5\u65e0\u5173\uff0c\u53ea\u80fd\u901a\u8fc7\u80a0\u9053\u83cc\u7fa4\u5f71\u54cd\u7cbe\u795e\u75c5\uff0c\u8fd9\u65f6\u7684SNP\u5c31\u53ef\u4ee5\u4f5c\u4e3a\u5de5\u5177\u53d8\u91cf\u66ff\u4ee3\u80a0\u9053\u83cc\u7fa4\uff0c\u53bb\u7814\u7a76\u80a0\u9053\u83cc\u7fa4\u548c\u7cbe\u795e\u75c5\u4e4b\u95f4\u7684\u5173\u7cfb\u3002<\/span><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 16px;\">\u8bf4\u5230\u8fd9\uff0c\u5927\u5bb6\u662f\u4e0d\u662f\u5bf9\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u66f4\u52a0\u660e\u767d\u4e86\u5462\uff0c\u60f3\u8981\u7528\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u4e0d\u7528\u505a\u5b9e\u9a8c\u5c31\u53d1\u8868Q1\u533a15\u5206+\u7684\u6587\u7ae0\u4e48\uff0c\u8ba9\u6211\u4eec\u4e00\u8d77\u6765\u770b\u4e00\u4e0b\u8fd9\u7bc7\u6587\u7ae0\u5427\uff01<\/span><\/p>\n<p style=\"outline: 0px;font-family: system-ui, -apple-system, "system-ui", "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);visibility: visible;margin-bottom: 24px;\"><span style=\"outline: 0px;color: rgb(0, 82, 255);visibility: visible;\"><strong style=\"outline: 0px;visibility: visible;\"><span style=\"outline: 0px;font-size: 16px;visibility: visible;\">\uff08PS\uff1a\u6ca1\u6709\u601d\u8def\u3001\u4e0d\u77e5\u9053\u600e\u4e48\u521b\u65b0\u7684\u5b9d\u5b50\u4eec\uff0c\u8bb0\u5f97\u6765\u627e\u5c0f\u9014\u54e6\uff0c\u8d85\u591a\u4e2a\u6027\u5316\u601d\u8def\u7b49\u4f60\u6765\u62ff\uff01\uff09<\/span><\/strong><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-imgfileid=\"100017027\" data-ratio=\"1\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_B2jkicacLzPjw4xMSqVvoucZjonVDA-11.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAxVYfSsM0wdf9d3RpNiaTcHohxPNEVs2VFhPMukpU8lchxrvcB2jkicacLzPjw4xMSqVvoucZjonVDA\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"430\" style=\"width: 189px;height: 189px;\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100009261\" data-ratio=\"0.42455775234131116\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_0Q0csfom4WOdIjElHnBMDlaFpXkwHA-3.png?resize=553%2C234\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LRadoia20IpY6458dCqKMpRDPtLnia5Hjou8gtIjb4TcsByyic0Q0csfom4WOdIjElHnBMDlaFpXkwHA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"961\" height=\"234 .8699951171875\" width=\"553 .739990234375\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 16px;\">\u9898\u76ee\uff1a\u5bbf\u4e3b\u57fa\u56e0\u7ec4\u548c\u80a0\u9053\u5fae\u751f\u7269\u7ec4\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u589e\u52a0\u4e86\u7cbe\u795e\u75be\u75c5\u7684\u98ce\u9669:\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u548c\u751f\u7269\u6ce8\u91ca    <\/span><o:page><\/o:page><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 16px;\">\u6742\u5fd7\uff1aBRAIN BEHAVIOR AND IMMUNITY<\/span><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 16px;\">\u5f71\u54cd\u56e0\u5b50\uff1aIF=15.1\/Q1<\/span><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 16px;\">\u53d1\u8868\u65f6\u95f4\uff1a2023\u5e748\u67088\u65e5<\/span><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;letter-spacing: 0.034em;font-size: 16px;\">         <\/span><o:p style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;font-size: var(--articleFontsize);letter-spacing: 0.034em;\"><span style=\"font-size: 16px;\"> <\/span><\/o:p><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><span style=\"color: rgb(0, 82, 255);\"><strong><span style=\"color: rgb(0, 82, 255);font-size: 18px;\">\u7814\u7a76\u80cc\u666f<\/span><\/strong><\/span><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 16px;\">\u5927\u91cf\u5f00\u521b\u6027\u7684\u7814\u7a76\u8868\u660e\u80a0\u9053\u83cc\u7fa4\u5bf9\u5927\u8111\u795e\u7ecf\u548c\u529f\u80fd\u6709\u91cd\u8981\u5f71\u54cd\u3002\u4e14\u60a3\u6709\u7cbe\u795e\u75be\u75c5\u7684\u4e2a\u4eba\u7684\u80a0\u9053\u83cc\u7fa4\u4e0e\u6b63\u5e38\u4eba\u7684\u83cc\u7fa4\u662f\u4e0d\u540c\u7684\u3002\u4eba\u7c7b\u57fa\u56e0\u7ec4\u548c\u80a0\u9053\u83cc\u7fa4\u7684\u5168\u57fa\u56e0\u7ec4\u5173\u8054\u5206\u6790\uff08mbGWAS\uff09\u8868\u660e\u4e24\u8005\u6709\u8f83\u5f3a\u7684\u76f8\u4e92\u4f5c\u7528\u3002\u7136\u800c\uff0c\u8fd9\u4e9b\u7ec4\u5b66\u7814\u7a76\u7684\u4e00\u4e2a\u4e3b\u8981\u7684\u6311\u6218\u5c31\u662f\u9700\u8981\u5927\u91cf\u7684\u6837\u672c\uff0c\u77ed\u65f6\u95f4\u5f88\u96be\u5b9e\u73b0\uff0c\u56e0\u6b64\uff0c\u4e00\u4e2a\u66ff\u4ee3\u7684\u65b9\u6cd5\u5c31\u662f\u7528\u8ba1\u7b97\u673a\u6a21\u62df\u7684\u65b9\u6cd5\u5c06\u8fd9\u4e9b\u7814\u7a76\u7ed3\u5408\u8d77\u6765\u63d0\u5347\u7edf\u8ba1\u80fd\u529b\u3002<\/span><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 16px;\">\u53e6\u5916\uff0c\u6709\u8bc1\u636e\u8868\u660e\u7cbe\u795e\u75be\u75c5\u60a3\u8005\u7684\u80a0\u9053\u83cc\u7fa4\u51fa\u73b0\u7d0a\u4e71\uff0c\u4f46\u539f\u56e0\u672a\u77e5\uff0c\u53ef\u80fd\u662f\u5f88\u591a\u73af\u5883\u56e0\u7d20\uff0c\u56e0\u6b64\u8fd9\u4e9b\u6df7\u6742\u7684\u56e0\u7d20\u8ba9\u4f5c\u8005\u5f88\u96be\u53bb\u5206\u6790\u80a0\u9053\u83cc\u7fa4\u7d0a\u4e71\u548c\u7cbe\u795e\u75be\u75c5\u4e4b\u95f4\u7684\u5173\u7cfb\u3002\u56e0\u6b64\u4f5c\u8005\u5229\u7528\u4e86meta\u5206\u6790\u548c\u53cc\u6837\u672c\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u7684\u65b9\u6cd5\uff0c\u5206\u6790\u4e86\u83cc\u7fa4\u548c\u7cbe\u795e\u75be\u75c5\u4e4b\u95f4\u7684\u5173\u7cfb\uff0c\u5e76\u4e14\u5bf9\u8fd9\u4e9b\u5173\u7cfb\u63d0\u4f9b\u4e86\u751f\u7269\u6ce8\u91ca\uff0c\u89e3\u51b3\u4e86\u4e4b\u524d\u5b58\u5728\u7684\u9650\u5236\u3002<\/span><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;letter-spacing: 0.034em;font-size: 16px;\">         <\/span><o:p style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;font-size: var(--articleFontsize);letter-spacing: 0.034em;\"><span style=\"font-size: 16px;\"> <\/span><\/o:p><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><span style=\"color: rgb(0, 82, 255);\"><strong><span style=\"color: rgb(0, 82, 255);font-size: 18px;\">\u6570\u636e\u6765\u6e90<\/span><\/strong><\/span><o:page><\/o:page><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100009264\" data-ratio=\"0.5777777777777777\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_ibB394KjvdAIckx6S2CLovb8uFpZwg-3.png?resize=410%2C237\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LRadoia20IpY6458dCqKMpRDpGLgiblVhUY7x4efYJT65C2DTxibB394KjvdAIckx6S2CLovb8uFpZwg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" height=\"237 .27001953125\" width=\"410 .8699951171875\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><span style=\"color: rgb(0, 82, 255);\"><strong><span style=\"color: rgb(0, 82, 255);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;letter-spacing: 0.034em;font-size: 18px;\">\u7814\u7a76\u601d\u8def<\/span><\/strong><\/span><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 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style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;letter-spacing: 0.034em;font-size: 16px;\">         <\/span><o:p style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;font-size: var(--articleFontsize);letter-spacing: 0.034em;\"><span style=\"font-size: 16px;\"> <\/span><\/o:p><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;letter-spacing: 0.034em;font-size: 16px;\">    <\/span><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;font-size: var(--articleFontsize);letter-spacing: 0.034em;\"><\/span><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100009263\" data-ratio=\"1.1780045351473922\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_oHuFiato44xIkxaarxlWpqEbcvNiaQ-3.jpg?resize=529%2C624\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/hud5kpqc1LRadoia20IpY6458dCqKMpRD5foQ2Ck7V9U4ScyJO0fuJZ9ZFVoHuFiato44xIkxaarxlWpqEbcvNiaQ\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"882\" height=\"624 .010009765625\" width=\"529 .3400268554688\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><span style=\"font-size: 14px;\">\u56fe1 \u672c\u7814\u7a76\u6d41\u7a0b\u56fe<\/span><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><span style=\"color: rgb(0, 82, 255);\"><strong><span style=\"color: rgb(0, 82, 255);font-size: 18px;\">\u4e3b\u8981\u7ed3\u679c<\/span><\/strong><\/span><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 16px;background-color: rgb(61, 170, 214);color: rgb(255, 255, 255);\">1.Meta \u5206\u6790<\/span><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 16px;\">\u5728mbGWAS\u4e2d\u8fdb\u884c\u7684METAL\u548cMTAG\u6cd5\u63d0\u9ad8\u4e86\u57fa\u56e0\u4f18\u5148\u7ea7\u6392\u5e8f\u548c\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u5206\u6790\u7684\u80fd\u529b\u3002\u5bf9\u4e8eMETAL\u5206\u6790\uff0cSNPs\u5177\u6709\u5f02\u8d28\u6027\u7684\u88ab\u6392\u9664\uff0c\u5bf9\u4e8eMTAG\uff0c\u5e73\u5747\u03c72\u5c0f\u4e8e1.02\u7684\u88ab\u6392\u9664\u3002\u4f7f\u7528METAL\u8fd9\u4e2a\u65b9\u6cd5\u4e4b\u540e\uff0c\u7ed3\u679c\u53d1\u73b0\u7684\u4e3b\u8981SNPs\u6570\u91cf\u589e\u52a0\uff0c\u6bd4\u5bf9\u4e0a\u7684\u57fa\u56e0\u6570\u91cf\u589e\u52a0,\u3002\u4f5c\u8005\u4e5f\u6bd4\u8f83\u4e86GWAS\u548cMTAG\u540e\u7684\u7ed3\u679c\uff0c\u5e76\u4e14MTAG\u5206\u6790\u4f7f\u5f97\u83b7\u5f97\u7684\u6837\u672c\u91cf\u589e\u52a0\uff0c\u4f8b\u5982\uff0c\u957f\u53cc\u6b67\u6746\u83ccBifidobacterium longum\u7684\u4e3b\u8981SNP\u7684\u6570\u91cf\u4ece15\u4e2a\u6da8\u523033\u4e2a\uff0c\u53cd\u520d\u53cc\u6b67\u6746\u83ccBifidobacterium ruminantium\u7684\u4e3b\u8981SNP\u4ece29\u4e2a\u6da8\u523034\u4e2a\uff0c\u6700\u7ec8\u7edf\u8ba1\u80fd\u529b\u7684\u5347\u9ad8\u4f7f\u7528\u5e73\u5747\u5361\u65b9\u7edf\u8ba1\u5206\u6790\u7684\uff0c\u7ed3\u679c\u53d1\u73b0\u76f8\u5f53\u4e8e\u628a\u539f\u59cb\u6837\u672c\u76847%\u6269\u5927\u523063%\u3002   <\/span><o:page><\/o:page><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 16px;background-color: rgb(61, 170, 214);color: rgb(255, 255, 255);\">2.\u53cc\u5411\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u5206\u6790<\/span><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 16px;\">\u4f5c\u8005\u7528\u4e86\u53cc\u5411\u53cc\u6837\u672c\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u548cMETAL\u53caMTAG\u5206\u6790\uff0c\u786e\u8ba4\u4e863\u4e2a\u83cc\u7fa4\u7279\u5f81\u548c2\u4e2a\u7cbe\u795e\u6027\u75be\u75c5\u5305\u62ec\u591a\u52a8\u75c7\uff08ADHD\uff09\u548c\u521b\u4f24\u6027\u540e\u9057\u75c7\uff08PTSD\uff09\u4e4b\u95f4\u7684\u6f5c\u5728\u8054\u7cfb\u3002\u4f5c\u8005\u53d1\u73b0\u62df\u6746\u83cc\u5c5e\uff08Bacteroides faecis\uff09\u5bf9ADHD\u7684\u5f71\u54cd\u6709\u6b63\u5411\u6548\u5e94(OR, 1.09; 95% CI, 1.02\u20131.16; P = 0.008)\u3002Bacteroides faecis\u7684\u4e30\u5ea6\u6bcf\u589e\u52a01s.d.\uff0cADHD\u7684\u53d1\u75c5\u98ce\u9669\u589e\u52a09%\u3002\u827e\u6c0f\u62df\u6746\u83cc\uff08Bacteroides eggerthii\uff09\u4e30\u5ea6\u548cPTSD\u7684\u53d1\u75c5\u98ce\u9669\u4e5f\u5448\u6b63\u76f8\u5173(OR, 1.11; 95% CI, 1.03\u20131.20; P = 0.007)\u3002\u591a\u5f62\u62df\u6746\u83cc\uff08Bacteroides thetaiotaomicron\uff09\u4e5f\u88ab\u53d1\u73b0\u548cPTSD\u53d1\u75c5\u7387\u5448\u6b63\u76f8\u5173(OR, 1.11; 95% CI, 1.01\u20131.23; P = 0.03)\u3002Bacteroides eggerthii \u548c Bacteroides thetaiotaomicron.\u6bcf\u589e\u52a01s.d.\uff0cPTSD\u53d1\u75c5\u98ce\u9669\u589e\u52a011%\uff08\u56fe2 A\uff09\u3002\u4f5c\u8005\u4e5f\u53d1\u73b0\u8fd9\u4e09\u79cd\u83cc\u7fa4\u7279\u5f81\u7684SNPs\u5bf9\u8fd9\u4e24\u79cd\u7cbe\u795e\u75be\u75c5\u7684\u5f71\u54cd\u662f\u5448\u6b63\u76f8\u5173\u7684\uff08\u56fe2 B\uff09\u3002   <\/span><o:page><\/o:page><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100009265\" data-ratio=\"0.8083333333333333\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_p1hvKolscJUECR2AHsLmBdfzaKBWsA-3.jpg?resize=540%2C437\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/hud5kpqc1LRadoia20IpY6458dCqKMpRDNDVSjR3VyeeaspMibxhdzKlj1p1hvKolscJUECR2AHsLmBdfzaKBWsA\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"1080\" height=\"437 .010009765625\" width=\"540 .010009765625\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><span style=\"font-size: 14px;\">\u56fe2 \u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u5206\u6790<\/span><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"background-color: rgb(61, 170, 214);font-size: 16px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;letter-spacing: 0.034em;color: rgb(255, 255, 255);\">3.\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u654f\u611f\u5ea6\u5206\u6790<\/span><br \/><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 16px;\">\u654f\u611f\u5ea6\u5206\u6790\u5c31\u662f\u7528\u6765\u9274\u5b9a\u7ed3\u679c\u662f\u5426\u9760\u8c31\u7684\u65b9\u6cd5\u3002\u5e38\u7528\u7684\u65b9\u6cd5\u5c31\u662f\u201cleave-one-out\u201d\u6cd5\u3002\u201cleave-one-out\u201d\u6cd5\u6307\u7684\u662f\u9010\u6b65\u5254\u9664\u6bcf\u4e2aSNP\uff0c\u8ba1\u7b97\u5269\u4f59SNP\u7684meta\u6548\u5e94\uff0c\u89c2\u5bdf\u5254\u9664\u6bcf\u4e2aSNP\u540e\u7ed3\u679c\u662f\u5426\u53d1\u751f\u53d8\u5316\uff0c\u5982\u679c\u5254\u9664\u4e86\u67d0\u4e00\u4e2aSNP\u540e\uff0c\u7ed3\u679c\u6539\u53d8\u5f88\u5927\uff0c\u8bf4\u660e\u5b58\u5728\u67d0\u4e00\u4e2aSNP\u5bf9\u7ed3\u679c\u5f71\u54cd\u5f88\u5927\uff0c\u8fd9\u662f\u4f5c\u8005\u4e0d\u613f\u610f\u770b\u5230\u7684\u60c5\u51b5\u3002\u7406\u60f3\u7684\u60c5\u51b5\u5e94\u8be5\u662f\u9010\u6b65\u5254\u9664\u67d0\u4e2aSNP\u540e\u7ed3\u679c\u53d8\u5316\u4e0d\u5927\u3002\u5982\u4e0b\u56fe\u6240\u793a\uff0c\u5254\u9664\u6bcf\u4e2aSNP\u540e\uff0c\u603b\u4f53\u7684\u8bef\u5dee\u7ebf\u53d8\u5316\u4e0d\u5927\u8bf4\u660e\u7ed3\u679c\u662f\u9760\u8c31\u7684\uff08\u56fe3\uff09\u3002   <\/span><o:page><\/o:page><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100009266\" data-ratio=\"0.33055555555555555\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_bR2icX2g8oBoEkh7jhEGIgLbn8c5Pw-3.jpg?resize=553%2C183\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/hud5kpqc1LRadoia20IpY6458dCqKMpRD5tDa3oUHzdicEIubWtEw4oiaxBSibR2icX2g8oBoEkh7jhEGIgLbn8c5Pw\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"1080\" height=\"183 .39999389648438\" width=\"553 .739990234375\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><span style=\"font-size: 14px;\">\u56fe3 \u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u7684\u654f\u611f\u5ea6\u5206\u6790\uff08leave-one-out\u56fe\uff09<\/span><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"background-color: rgb(61, 170, 214);font-size: 16px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;letter-spacing: 0.034em;color: rgb(255, 255, 255);\">4.\u5171\u901a\u57fa\u56e0\u7684\u751f\u7269\u6ce8\u91ca<\/span><br \/><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 16px;\">\u4f7f\u7528\u5b57\u7b26\u4e32\u6570\u636e\u5e93\uff08STRING database\uff09\u8fdb\u884cPPI\u7f51\u7edc\u5206\u6790\u663e\u793a\uff0c\u7cbe\u795e\u75be\u75c5\u548c\u83cc\u7fa4\u7279\u5f81\u4e4b\u95f4\u5171\u540c\u7684168\u4e2a\u57fa\u56e0\u5f62\u6210\u4e86\u4e00\u4e2a\u7d27\u5bc6\u76f8\u8fde\u7684\u7f51\u7edc\uff08\u56fe4 A\uff09\u3002\u4e3a\u4e86\u786e\u5b9a\u4e0e\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u3001\u7cbe\u795e\u75be\u75c5\u53ca\u5176\u6f5c\u5728\u5173\u7cfb\u76f8\u5173\u7684\u5206\u5b50\u673a\u5236\uff0c\u4f5c\u8005\u5bf9\u8fd9\u4e9b\u57fa\u56e0\u8fdb\u884c\u4e86\u57fa\u56e0\u5bcc\u96c6\u5206\u6790\uff0c\u53d1\u73b0\u4e3b\u8981\u5bcc\u96c6\u5728\u5173\u4e8e\u4e00\u79cd\u7a81\u89e6\u7ec4\u7ec7\u6d3b\u52a8\u7684\u901a\u8def\u4e0a\uff08\u56fe4 B\uff09\u3002<\/span><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100009268\" data-ratio=\"0.5638888888888889\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/10_ag21M55vgGS6PTicmAkErnx7lduzWA-3.jpg?resize=553%2C312\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/hud5kpqc1LRadoia20IpY6458dCqKMpRD24HDGb9xs2Uj5URcy5ibYRSrIqag21M55vgGS6PTicmAkErnx7lduzWA\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"1080\" height=\"312 .0\" width=\"553 .739990234375\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><span style=\"font-size: 14px;\">\u56fe4 \u7cbe\u795e\u75be\u75c5\u548c\u83cc\u7fa4\u7279\u5f81\u4e4b\u95f4\u5171\u540c\u7684168\u4e2a\u57fa\u56e0\u7684\u751f\u7269\u6ce8\u91ca<\/span><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"background-color: rgb(61, 170, 214);font-size: 16px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;letter-spacing: 0.034em;color: rgb(255, 255, 255);\">5.\u5de5\u5177\u53d8\u91cf\uff08IVs\uff09\u7684\u751f\u7269\u6ce8\u91ca<\/span><br \/><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 16px;\">\u5728\u53cc\u5411\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u5206\u6790\u7684\u60c5\u51b5\u4e0b\uff0c3\u4e2a\u83cc\u7fa4\u7279\u5f81\u548c\u7cbe\u795e\u75be\u75c5\u76f8\u5173\u7684\u5de5\u5177\u53d8\u91cf\uff08\u603b\u517159\u4e2aSNP\uff09\u88ab\u6bd4\u5bf9\u523075\u4e2a\u57fa\u56e0\u4e0a\uff0c\u6839\u636eGWAS\u76ee\u5f55\uff0c\u8fd9\u4e9b\u57fa\u56e0\u4e3b\u8981\u4e0e\u6d77\u9a6c\u4f53\u4e9a\u533a\u57df\u4f53\u79ef\u548c\u603b\u4f53\u79ef\u76f8\u5173\uff08\u56fe5\uff09\u3002   <\/span><o:page><\/o:page><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100009269\" data-ratio=\"0.3388888888888889\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/11_Us8vyjqcQRxzIjakia90RfzDXuKFGA-3.jpg?resize=553%2C187\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/hud5kpqc1LRadoia20IpY6458dCqKMpRDPhbFLD5S5RupzYfdAFjtuaqibicUs8vyjqcQRxzIjakia90RfzDXuKFGA\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"1080\" height=\"187 .74002075195312\" width=\"553 .739990234375\" data-recalc-dims=\"1\" \/><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><span style=\"font-size: 14px;\">\u56fe5 \u83cc\u7fa4\u7279\u5f81\u548c\u7cbe\u795e\u75be\u75c5\u76f8\u5173\u7684\u5de5\u5177\u53d8\u91cf\uff08IVs\uff09\u7684\u751f\u7269\u6ce8\u91ca<\/span><\/p>\n<p style=\"text-align: center;margin-bottom: 24px;\"><span style=\"color: rgb(0, 82, 255);\"><strong><span style=\"color: rgb(0, 82, 255);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;letter-spacing: 0.034em;font-size: 18px;\">\u6587\u7ae0\u5c0f\u7ed3<\/span><\/strong><\/span><br \/><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 16px;\">\u6b64\u6587\u7ae0\u5728\u9057\u4f20\u5b66\u7edf\u8ba1\u7b56\u7565\u4e0a\u7528\u4e86METAL\u548cMTAG\uff0c\u6709\u52a9\u4e8e\u589e\u5f3a\u5bf9mbGWAS\u9057\u4f20\u53d8\u5f02\u57fa\u56e0\u7684\u7edf\u8ba1\u5206\u6790\u529b\u91cf\uff0c\u5e76\u4e14\u8054\u5408\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u7814\u7a76\u4e3a\u80a0\u9053\u83cc\u7fa4\u548c\u7cbe\u795e\u75be\u75c5\u4e4b\u95f4\u7684\u751f\u7269\u5b66\u591a\u6548\u6027\u548c\u56e0\u679c\u5173\u7cfb\u63d0\u4f9b\u4e86\u65b0\u7684\u89c1\u89e3\uff0c\u4e3a\u7cbe\u795e\u75be\u75c5\u4e4b\u540e\u7684\u6cbb\u7597\u63d0\u4f9b\u4e86\u65b0\u7684\u6cbb\u7597\u65b9\u5411\u548c\u89d2\u5ea6\uff0c\u5177\u6709\u6781\u9ad8\u7684\u521b\u65b0\u578b\u548c\u4e34\u5e8a\u610f\u4e49\u3002<\/span><\/p>\n<p style=\"margin-bottom: 24px;\"><span style=\"font-size: 16px;\">\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u601d\u8def\u7b80\u5355\uff0c\u7b80\u5355\u5206\u6790\u5c31\u80fd\u53d1\u9ad8\u5206\uff0c\u4f46\u5c0f\u9014\u544a\u8bc9\u5927\u5bb6\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u6700\u91cd\u8981\u7684\u5c31\u662f\u9009\u9898\uff0c\u6211\u4eec\u8981\u9009\u62e9\u7684\u662f\u90a3\u4e9b\u6ca1\u6709\u8fc7\u7814\u7a76\u7684\u65b9\u5411\uff0c\u662f\u90a3\u4e9b\u5177\u6709\u91cd\u8981\u4e34\u5e8a\u7814\u7a76\u610f\u4e49\u7684\u6587\u7ae0\uff0c\u4e3e\u4e2a\u4f8b\u5b50\uff0c\u83cc\u7fa4\u548c\u7cbe\u795e\u75c5\u5df2\u7ecf\u7814\u7a76\u8fc7\uff0c\u6211\u4eec\u53ef\u4ee5\u7814\u7a76\u83cc\u7fa4\u7d0a\u4e71\u548c\u963f\u5c14\u5179\u6d77\u9ed8\u75c7\/\u75f4\u5446\/\u591a\u52a8\u75c7\/\u6291\u90c1\u75c7\/\u7cbe\u795e\u5206\u88c2\u7b49\u75be\u75c5\u4e4b\u95f4\u7684\u5173\u7cfb\u3002\u53ea\u8981\u5177\u6709\u8f83\u9ad8\u7684\u4e34\u5e8a\u610f\u4e49\uff0c\u4f60\u7684\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u5c31\u80fd\u53d1\u5230\u9ad8\u5206\u6742\u5fd7\u4e0a\uff08<strong><span style=\"font-size: 16px;color: rgb(0, 82, 255);\">ps\uff1a\u8fd8\u7b49\u4ec0\u4e48\uff0c\u6293\u7d27\u884c\u52a8\u8d77\u6765\u53ed\uff01<\/span><\/strong>\uff09\u3002<\/span><\/p>\n<p style=\"text-indent: 0px;margin-bottom: 0px;\"><span style=\"color: rgb(0, 122, 170);\"><strong><span style=\"color: rgb(0, 122, 170);letter-spacing: 0.578px;text-indent: 32px;text-wrap: wrap;background-color: rgb(255, 255, 255);font-size: 15px;\">\u5c0f\u679c\u8fd8<span style=\"color: rgb(0, 122, 170);background-color: rgb(255, 255, 255);font-size: 15px;letter-spacing: 0.578px;text-decoration: none solid rgba(0, 0, 0, 0.9);\">\u63d0\u4f9b\u601d\u8def\u8bbe\u8ba1\u3001\u5b9a\u5236\u751f\u4fe1\u5206\u6790\u3001\u6587\u732e\u601d\u8def\u590d\u73b0\uff1b\u6709\u9700\u8981\u7684\u5c0f\u4f19\u4f34\u6b22\u8fce\u76f4\u63a5\u626b\u7801\u54a8\u8be2\u5c0f\u679c\uff0c\u7aed\u8bda\u4e3a\u60a8\u7684\u79d1\u7814\u52a9\u529b\uff01<\/span><\/span><\/strong><\/span><\/p>\n<p style=\"margin-bottom: 0px;\"><br \/><\/p>\n<section style=\"font-size: 15px;padding-right: 2px;padding-left: 2px;margin-bottom: 0px;\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;flex: 0 0 auto;height: auto;border-color: rgb(114, 114, 114);border-width: 1px;border-style: solid;box-shadow: rgb(194, 209, 255) -5px 5px 0px;align-self: flex-start;\">\n<section style=\"justify-content: center;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 42.6829%;vertical-align: middle;box-shadow: rgb(43, 65, 110) 0px 0px 0px;flex: 0 0 auto;height: auto;padding-left: 10px;align-self: center;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;line-height: 0;transform: translate3d(20px, 0px, 0px);\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;width: 75%;height: auto;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-imgfileid=\"100017033\" data-ratio=\"1\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_B2jkicacLzPjw4xMSqVvoucZjonVDA-11.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAxVYfSsM0wdf9d3RpNiaTcHohxPNEVs2VFhPMukpU8lchxrvcB2jkicacLzPjw4xMSqVvoucZjonVDA\/640?wx_fmt=jpeg'&from=appmsg\" data-type=\"jpeg\" data-w=\"430\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: 56.9106%;flex: 0 0 auto;height: auto;align-self: center;\">\n<section style=\"line-height: 2;letter-spacing: 1px;color: rgb(43, 65, 110);\" powered-by=\"xiumi.us\">\n<p style=\"margin-bottom: 2px;\"><strong>\u5b9a\u5236\u751f\u4fe1\u5206\u6790<\/strong><\/p>\n<p style=\"margin-bottom: 2px;\"><strong>\u670d\u52a1\u5668\u79df\u8d41<\/strong><\/p>\n<p><strong>\u626b\u7801\u54a8\u8be2\u5c0f\u679c<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247497780&idx=2&sn=7eee90af6f387e4153bba13028e545a1&chksm=cf7f68f1f808e1e7dfb3a0597ef442e5c6e700ecf6ee5a035c766a4c7486c12eabd0ab218ea6&scene=21#wechat_redirect\" textvalue=\"\u4f60\u5df2\u9009\u4e2d\u4e86\u6dfb\u52a0\u94fe\u63a5\u7684\u5185\u5bb9\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"1\" rel=\"noopener\"><span class=\"js_jump_icon h5_image_link\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-imgfileid=\"100017034\" data-ratio=\"0.3253333333333333\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/13_7TvAyUibd1TPhJmZfialJtv6tu2SEg-26.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAxVYfSsM0wdf9d3RpNiaTcHoj9xlsoyiaBvzaezDUFAicibMAF8ts7TvAyUibd1TPhJmZfialJtv6tu2SEg\/640?wx_fmt=png&from=appmsg'\" data-type=\"png\" data-w=\"750\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/span><\/a><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img js_insertlocalimg\" data-imgfileid=\"100017032\" data-ratio=\"0.3811111111111111\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/14_9N02aBaau07RufXeXRLmvAHsrFZxtw-25.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAz5wg6Ne6sYkannSE9NiatkcPh3icbKanJagacjU6LqJrGAL29N02aBaau07RufXeXRLmvAHsrFZxtw\/640?wx_fmt=jpeg&from=appmsg'\" data-type=\"jpeg\" data-w=\"900\" style=\"letter-spacing: 0.578px;text-align: center;text-wrap: wrap;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;text-align: left;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-end;padding-right: 2px;padding-left: 2px;\">\n<section style=\"margin: 10px 0% 2px;transform: translate3d(2px, 0px, 0px);\" powered-by=\"xiumi.us\">\n<section style=\"font-size: 16px;color: rgb(58, 66, 94);line-height: 1;letter-spacing: 5px;text-align: center;\">\n<p><strong>\u5f80\u671f\u56de\u987e<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"height: 3px;background-color: rgb(95, 156, 239);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<section style=\"margin-top: 2px;margin-right: 0%;margin-left: 0%;text-align: center;line-height: 0.8;font-size: 9px;\" powered-by=\"xiumi.us\">\n<section style=\"width: 0px;display: inline-block;border-top: 0.8em solid rgb(58, 66, 94);border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;flex: 100 100 0%;align-self: flex-end;height: auto;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"height: 3px;background-color: rgb(95, 156, 239);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<section style=\"margin-top: 2px;margin-right: 0%;margin-left: 0%;text-align: center;line-height: 0.8;font-size: 9px;\" powered-by=\"xiumi.us\">\n<section style=\"width: 0px;display: inline-block;border-top: 0.8em solid rgba(255, 255, 255, 0);border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"min-height: 40px;margin: 10px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"width: 100%;margin-right: auto;margin-bottom: -10px;margin-left: auto;\">\n<table width=\"100%\">\n<tbody>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:0\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:0.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>01<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247497780&idx=2&sn=7eee90af6f387e4153bba13028e545a1&chksm=cf7f68f1f808e1e7dfb3a0597ef442e5c6e700ecf6ee5a035c766a4c7486c12eabd0ab218ea6&scene=21#wechat_redirect\" textvalue=\"1024G\u5b58\u50a8\u7684\u751f\u4fe1\u670d\u52a1\u5668\uff0c\u4e24\u4eba\u6210\u56e2\uff0c1\u4eba\u514d\u5355\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">1024G\u5b58\u50a8\u7684\u751f\u4fe1\u670d\u52a1\u5668\uff0c\u4e24\u4eba\u6210\u56e2\uff0c1\u4eba\u514d\u5355\uff01<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:1\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:1.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>02<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247498878&idx=1&sn=fc34ed3f1d15d060bbaf8166adcebd58&chksm=cf7f6cbbf808e5ad0b5417e50ed75cfbd1b3a83ac43b97f1dfa718c822878a9a004990075133&scene=21#wechat_redirect\" textvalue=\"\u5355\u4e2a\u6570\u636e\u5e93\u7528\u817b\u4e86\uff1f\u591a\u6570\u636e\u5e93\u201c\u7ec4\u5408\u62f3\u201d\u5e26\u4f60\u6253\u5f00\u514d\u75ab\u6d78\u6da6\u65b0\u601d\u8def\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u5355\u4e2a\u6570\u636e\u5e93\u7528\u817b\u4e86\uff1f\u591a\u6570\u636e\u5e93\u201c\u7ec4\u5408\u62f3\u201d\u5e26\u4f60\u6253\u5f00\u514d\u75ab\u6d78\u6da6\u65b0\u601d\u8def\uff01<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:2\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:2.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>03<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247498673&idx=1&sn=1e09b74a836c1e64a62ae1f66eeb3f93&chksm=cf7f6b74f808e262de70be43fd73bf5fefdc0914e525eb2032f741a0152e619689cedc76946f&scene=21#wechat_redirect\" textvalue=\"\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u7684\u51c6\u5907\u5de5\u4f5c\uff0cGWAS\u6570\u636e\u7684\u7f51\u7ad9\u4e0b\u8f7d\u65b9\u6cd5\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"11\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u7684\u51c6\u5907\u5de5\u4f5c\uff0cGWAS\u6570\u636e\u7684\u7f51\u7ad9\u4e0b\u8f7d\u65b9\u6cd5<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:3\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:3.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>04<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" 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