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data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"display: flex;flex-direction: column;align-self: center;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"border-width: 1px;border-style: solid;border-color: rgb(74, 74, 74);padding: 0px 5px;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"display: flex;justify-content: center;align-items: center;padding: 6px 8px;background: #F6801F;border-left: 1px solid #4A4A4A;border-right: 1px solid #4A4A4A;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"width: 20px;height: 15px;display: flex;justify-content: center;align-items: center;flex-shrink: 0;\" data-mid=\"\" mpa-from-tpl=\"t\"><br \/><\/section>\n<section style=\"min-width: 100px;text-align: center;padding: 0 8px;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<p style=\"font-size: 16px;font-weight: bold;color: #FFFFFF;line-height: 22px;word-break: break-word;\" data-mid=\"\" mpa-is-content=\"t\">\u7814\u7a76\u80cc\u666f<\/p>\n<\/section>\n<section style=\"width: 20px;height: 15px;display: flex;justify-content: center;align-items: center;flex-shrink: 0;transform: rotateY(180deg);\" data-mid=\"\" mpa-from-tpl=\"t\"><br \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"mso-style-parent: '';margin-top: 0.0pt;margin-bottom: 0.0pt;text-align: justify;text-justify: inter-ideograph;margin-left: 0.0pt;line-height: 22.0pt;font-size: 12.0pt;font-family: Times New Roman;font-weight: normal;text-indent: 24.0pt;\"><span style=\"font-family:\u5b8b\u4f53;\">\u4e73<\/span><span style=\"font-family:\u5b8b\u4f53;\">\u817a\u764c\uff08BC\uff09\u662f\u5168\u7403\u5973\u6027\u4e2d\u6700\u666e\u904d\u7684\u6076\u6027\u80bf\u7624\u4e4b\u4e00\uff0c\u5176\u53d1\u75c5\u7387\u6bcf\u5e74\u90fd\u5728\u589e\u52a0\u3002\u81ea2020\u5e74\u4ee5\u6765\uff0c\u5b83\u5df2\u8d85\u8fc7\u80ba\u764c\u6210\u4e3a\u4e16\u754c\u4e0a\u6700\u5927\u7684\u764c\u75c7\u3002BC\u662f\u4e00\u79cd\u9ad8\u5ea6\u5f02\u8d28\u6027\u75be\u75c5\uff0c\u56e0\u6b64\u8868\u660e\u57fa\u56e0\u8868\u8fbe\u8c31\u3001\u4e34\u5e8a\u75c5\u7406\u7279\u5f81\u548c\u751f\u7269\u5b66\u884c\u4e3a\u5b58\u5728\u5de8\u5927\u5dee\u5f02\u3002\u80bf\u7624\u5206\u671f\u3001\u7ec4\u7ec7\u5b66\u5206\u7ea7\u548c\u5206\u5b50\u4e9a\u578b\u5e38\u4f5c\u4e3a\u4e34\u5e8a\u4e0a\u8bc4\u4f30BC\u60a3\u8005\u7684\u9884\u540e\u56e0\u7d20\u3002\u7136\u800c\uff0cBC\u60a3\u8005\u7684\u9884\u540e\u4fe1\u606f\u65e0\u6cd5\u901a\u8fc7\u8fd9\u4e9b\u4e34\u5e8a\u7279\u5f81\u51c6\u786e\u9884\u6d4b\uff0c\u4ece\u800c\u5bfc\u81f4\u60a3\u8005\u9884\u540e\u8bca\u65ad\u4e0d\u51c6\u786e\u3002\u4e00\u4e9b\u4f4e\u5371\u60a3\u8005\u53ef\u80fd\u5f97\u5230\u4e0d\u5fc5\u8981\u6216\u8fc7\u5ea6\u7684\u6cbb\u7597\uff0c\u800c\u590d\u53d1\u6216\u8f6c\u79fb\u98ce\u9669\u9ad8\u7684\u60a3\u8005\u53ef\u80fd\u6cbb\u7597\u4e0d\u8db3\u3002\u56e0\u6b64\uff0c\u6709\u5fc5\u8981\u5229\u7528\u65b0\u7684\u9884\u540e\u751f\u7269\u6807\u5fd7\u7269\u548c\u76f8\u5e94\u7684\u9884\u6d4b\u6a21\u578b\u5bf9BC\u5f02\u8d28\u6027\u4eba\u7fa4\u8fdb\u884c\u98ce\u9669\u5206\u5c42\uff0c\u5e76\u6307\u5bfc\u4e2a\u4f53\u5316\u6cbb\u7597\u3002<\/span><\/p>\n<p style=\"margin-top: 0pt;margin-bottom: 0pt;text-align: center;margin-left: 0pt;text-indent: 0pt;line-height: 22pt;font-size: 12pt;font-family: "Times New Roman";font-weight: normal;\"><span style=\"font-family:\u5b8b\u4f53;font-weight:bold;\"><br mpa-from-tpl=\"t\" \/><\/span><\/p>\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\" style=\"margin-bottom: 24px;\">\n<section style=\"display: flex;flex-direction: column;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"display: flex;flex-direction: column;align-self: center;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"border-width: 1px;border-style: solid;border-color: rgb(74, 74, 74);padding: 0px 5px;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"display: flex;justify-content: center;align-items: center;padding: 6px 8px;background: #F6801F;border-left: 1px solid #4A4A4A;border-right: 1px solid #4A4A4A;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"width: 20px;height: 15px;display: flex;justify-content: center;align-items: center;flex-shrink: 0;\" data-mid=\"\" mpa-from-tpl=\"t\"><br \/><\/section>\n<section style=\"min-width: 100px;text-align: center;padding: 0 8px;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<p style=\"font-size: 16px;font-weight: bold;color: #FFFFFF;line-height: 22px;word-break: break-word;\" data-mid=\"\" mpa-is-content=\"t\">\u6570\u636e\u4fe1\u606f<\/p>\n<\/section>\n<section style=\"width: 20px;height: 15px;display: flex;justify-content: center;align-items: center;flex-shrink: 0;transform: rotateY(180deg);\" data-mid=\"\" mpa-from-tpl=\"t\"><br \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<table border=\"1\" cellspacing=\"0\" cellpadding=\"0\" style=\"margin-left: 0px;border-width: initial;border-style: none;border-color: initial;border-collapse: collapse;width: 100%;\">\n<tbody>\n<tr>\n<td width=\"138\" valign=\"top\" style=\"width:103.7pt;border-top:solid windowtext 1.0pt;border-left:solid windowtext 1.0pt;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<p style=\"mso-style-parent: '';margin-top: 0.0pt;margin-bottom: 0.0pt;text-align: justify;text-justify: inter-ideograph;margin-left: 0.0pt;text-indent: 0.0pt;line-height: 22.0pt;font-size: 12.0pt;font-family: Times New Roman;font-weight: normal;\"><span style=\"font-family:\u5b8b\u4f53;\">\u6570<\/span><span style=\"font-family:\u5b8b\u4f53;\">\u636e\u96c6\/\u961f\u5217<\/span><span style=\"font-family:Times New Roman;\"><\/span><\/p>\n<\/td>\n<td width=\"138\" valign=\"top\" style=\"width:103.7pt;border-top:solid windowtext 1.0pt;border-left:solid windowtext 1.0pt;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<p style=\"mso-style-parent: '';margin-top: 0.0pt;margin-bottom: 0.0pt;text-align: justify;text-justify: inter-ideograph;margin-left: 0.0pt;text-indent: 0.0pt;line-height: 22.0pt;font-size: 12.0pt;font-family: Times New Roman;font-weight: normal;\"><span style=\"font-family:\u5b8b\u4f53;\">\u6570\u636e\u5e93<\/span><span style=\"font-family:Times New Roman;\"><\/span><\/p>\n<\/td>\n<td width=\"138\" valign=\"top\" style=\"width:103.7pt;border-top:solid windowtext 1.0pt;border-left:solid windowtext 1.0pt;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<p style=\"mso-style-parent: '';margin-top: 0.0pt;margin-bottom: 0.0pt;text-align: justify;text-justify: inter-ideograph;margin-left: 0.0pt;text-indent: 0.0pt;line-height: 22.0pt;font-size: 12.0pt;font-family: Times New Roman;font-weight: normal;\"><span style=\"font-family:\u5b8b\u4f53;\">\u6837\u672c\u4fe1\u606f<\/span><span style=\"font-family:Times New Roman;\"><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"138\" valign=\"top\" style=\"width:103.7pt;border-top:solid windowtext 1.0pt;border-left:solid windowtext 1.0pt;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<p style=\"mso-style-parent: '';margin-top: 0.0pt;margin-bottom: 0.0pt;text-align: justify;text-justify: inter-ideograph;margin-left: 0.0pt;text-indent: 0.0pt;line-height: 22.0pt;font-size: 12.0pt;font-family: Times New Roman;font-weight: normal;\"><span style=\"font-family:Times New Roman;\">GSE20685<\/span><span style=\"font-family:Times New Roman;\"><\/span><\/p>\n<\/td>\n<td width=\"138\" valign=\"top\" style=\"width:103.7pt;border-top:solid windowtext 1.0pt;border-left:solid windowtext 1.0pt;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<p style=\"mso-style-parent: '';margin-top: 0.0pt;margin-bottom: 0.0pt;text-align: justify;text-justify: inter-ideograph;margin-left: 0.0pt;text-indent: 0.0pt;line-height: 22.0pt;font-size: 12.0pt;font-family: Times New Roman;font-weight: normal;\"><span style=\"font-family:Times New Roman;\">GEO<\/span><span style=\"font-family:Times New Roman;\"><\/span><\/p>\n<\/td>\n<td width=\"138\" valign=\"top\" style=\"width:103.7pt;border-top:solid windowtext 1.0pt;border-left:solid windowtext 1.0pt;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<p style=\"mso-style-parent: '';margin-top: 0.0pt;margin-bottom: 0.0pt;text-align: justify;text-justify: inter-ideograph;margin-left: 0.0pt;text-indent: 0.0pt;line-height: 22.0pt;font-size: 12.0pt;font-family: Times New Roman;font-weight: normal;\"><span style=\"font-family:Times New Roman;\">327\u4f8bBRCA\u60a3\u8005<\/span><span style=\"font-family:Times New Roman;\"><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"138\" valign=\"top\" style=\"width:103.7pt;border-top:solid windowtext 1.0pt;border-left:solid windowtext 1.0pt;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<p style=\"mso-style-parent: '';margin-top: 0.0pt;margin-bottom: 0.0pt;text-align: justify;text-justify: inter-ideograph;margin-left: 0.0pt;text-indent: 0.0pt;line-height: 22.0pt;font-size: 12.0pt;font-family: Times New Roman;font-weight: normal;\"><span style=\"font-family:Times New Roman;\">TCGA-BRCA<\/span><span style=\"font-family:Times New Roman;\"><\/span><\/p>\n<\/td>\n<td width=\"138\" valign=\"top\" style=\"width:103.7pt;border-top:solid windowtext 1.0pt;border-left:solid windowtext 1.0pt;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<p style=\"mso-style-parent: '';margin-top: 0.0pt;margin-bottom: 0.0pt;text-align: justify;text-justify: inter-ideograph;margin-left: 0.0pt;text-indent: 0.0pt;line-height: 22.0pt;font-size: 12.0pt;font-family: Times New Roman;font-weight: normal;\"><span style=\"font-family:Times New Roman;\">TCGA<\/span><\/p>\n<\/td>\n<td width=\"138\" valign=\"top\" style=\"width:103.7pt;border-top:solid windowtext 1.0pt;border-left:solid windowtext 1.0pt;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<p style=\"mso-style-parent: '';margin-top: 0.0pt;margin-bottom: 0.0pt;text-align: justify;text-justify: inter-ideograph;margin-left: 0.0pt;text-indent: 0.0pt;line-height: 22.0pt;font-size: 12.0pt;font-family: Times New Roman;font-weight: normal;\"><span style=\"font-family:Times New Roman;\">1022\u4e2aBC\u6837\u672c\u548c112\u4e2a\u914d\u5bf9\u6b63\u5e38\u6837\u672c<\/span><span style=\"font-family:Times New Roman;\"><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"138\" valign=\"top\" style=\"width: 103.7pt;border-width: 1pt;border-style: solid;border-color: windowtext;padding: 0pt 5.4pt;word-break: break-all;\">\n<p style=\"mso-style-parent: '';margin-top: 0.0pt;margin-bottom: 0.0pt;text-align: justify;text-justify: inter-ideograph;margin-left: 0.0pt;text-indent: 0.0pt;line-height: 22.0pt;font-size: 12.0pt;font-family: Times New Roman;font-weight: normal;\"><span style=\"font-family:\u5b8b\u4f53;\">\u8870\u8001\u76f8\u5173\u6807\u5fd7\u7269\uff08\u5305\u62ecp6\u3001p3\u3001p13\u3001TNF-\u03b1\u3001IL-2023\u3001FGF\u3001VEGF\u548cMMP-56\uff09<\/span><\/p>\n<\/td>\n<td width=\"138\" valign=\"top\" style=\"width:103.7pt;border-top:solid windowtext 1.0pt;border-left:solid windowtext 1.0pt;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<p style=\"mso-style-parent: '';margin-top: 0.0pt;margin-bottom: 0.0pt;text-align: justify;text-justify: inter-ideograph;margin-left: 0.0pt;text-indent: 0.0pt;line-height: 22.0pt;font-size: 12.0pt;font-family: Times New Roman;font-weight: normal;\"><span style=\"font-family:Times New Roman;\">HPA<\/span><\/p>\n<\/td>\n<td width=\"138\" valign=\"top\" style=\"width:103.7pt;border-top:solid windowtext 1.0pt;border-left:solid windowtext 1.0pt;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0pt 5.4pt 0pt 5.4pt;\">\n<p style=\"mso-style-parent: '';margin-top: 0.0pt;margin-bottom: 0.0pt;text-align: justify;text-justify: inter-ideograph;margin-left: 0.0pt;text-indent: 0.0pt;line-height: 22.0pt;font-size: 12.0pt;font-family: Times New Roman;font-weight: normal;\"><span style=\"font-family:\u5b8b\u4f53;\">\u8870\u8001\u76f8\u5173\u6807\u5fd7\u7269<\/span><span style=\"font-family:Times New Roman;\"><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"margin-top: 0pt;margin-bottom: 0pt;text-align: center;margin-left: 0pt;text-indent: 0pt;line-height: 22pt;font-size: 12pt;font-family: "Times New Roman";font-weight: normal;\"><br \/><\/p>\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\" style=\"margin-bottom: 24px;\">\n<section style=\"display: flex;flex-direction: column;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"display: flex;flex-direction: column;align-self: center;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"border-width: 1px;border-style: solid;border-color: rgb(74, 74, 74);padding: 0px 5px;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"display: flex;justify-content: center;align-items: center;padding: 6px 8px;background: #F6801F;border-left: 1px solid #4A4A4A;border-right: 1px solid #4A4A4A;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"width: 20px;height: 15px;display: flex;justify-content: center;align-items: center;flex-shrink: 0;\" data-mid=\"\" mpa-from-tpl=\"t\"><br \/><\/section>\n<section style=\"min-width: 100px;text-align: center;padding: 0 8px;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<p style=\"font-size: 16px;font-weight: bold;color: #FFFFFF;line-height: 22px;word-break: break-word;\" data-mid=\"\" mpa-is-content=\"t\">\u7814\u7a76\u601d\u8def<\/p>\n<\/section>\n<section style=\"width: 20px;height: 15px;display: flex;justify-content: center;align-items: center;flex-shrink: 0;transform: rotateY(180deg);\" data-mid=\"\" mpa-from-tpl=\"t\"><br \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin-top: 0pt;margin-bottom: 0pt;text-align: justify;margin-left: 0pt;line-height: 22pt;font-size: 12pt;font-family: "Times New Roman";font-weight: normal;text-indent: 0em;\"><span style=\"font-family:\u5b8b\u4f53;\">\u5229\u7528GEO\u3001TCGA\u7b49\u6570\u636e\u5e93\uff0c\u6574\u7406BC\u60a3\u8005\u7684\u8f6c\u5f55\u7ec4\u8868\u8fbe\u6570\u636e\u548c\u4e34\u5e8a\u6570\u636e\uff0c\u4f7f\u7528\u76ae\u5c14\u900a\u76f8\u5173\u5206\u6790\u7b5b\u9009\u4e86\u8870\u8001\u76f8\u5173lncRNA\u7684\u5dee\u5f02\u8868\u8fbe\uff0c\u6784\u5efa\u5e76\u9a8c\u8bc1\u8870\u8001\u76f8\u5173lncRNA\u9884\u540e\u7279\u5f81\uff0c\u7136\u540e\u8fdb\u884c\u514d\u75ab\u6d78\u6da6\u5206\u6790\u4ee5\u521b\u5efa\u5168\u65b0\u7684lncRNA\u8870\u8001\u9884\u6d4b\u7279\u5f81\u3002<\/span><span style=\"font-family:Times New Roman;\"><\/span><\/section>\n<p style=\"margin-top: 0pt;margin-bottom: 0pt;text-align: center;margin-left: 0pt;text-indent: 0pt;line-height: 22pt;font-size: 12pt;font-family: "Times New Roman";font-weight: normal;\"><span style=\"font-family:\u5b8b\u4f53;font-weight:bold;\"><br mpa-from-tpl=\"t\" \/><\/span><\/p>\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\" style=\"margin-bottom: 24px;\">\n<section style=\"display: flex;flex-direction: column;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"display: flex;flex-direction: column;align-self: center;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"border-width: 1px;border-style: solid;border-color: rgb(74, 74, 74);padding: 0px 5px;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"display: flex;justify-content: center;align-items: center;padding: 6px 8px;background: #F6801F;border-left: 1px solid #4A4A4A;border-right: 1px solid #4A4A4A;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"width: 20px;height: 15px;display: flex;justify-content: center;align-items: center;flex-shrink: 0;\" data-mid=\"\" mpa-from-tpl=\"t\"><br \/><\/section>\n<section style=\"min-width: 100px;text-align: center;padding: 0 8px;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<p style=\"font-size: 16px;font-weight: bold;color: #FFFFFF;line-height: 22px;word-break: break-word;\" data-mid=\"\" mpa-is-content=\"t\">\u7814\u7a76\u7ed3\u679c<\/p>\n<\/section>\n<section style=\"width: 20px;height: 15px;display: flex;justify-content: center;align-items: center;flex-shrink: 0;transform: rotateY(180deg);\" data-mid=\"\" mpa-from-tpl=\"t\"><br \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin-left: 22pt;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-family:Times New Roman;font-weight:bold;\">1.<span style=\"font:7.0pt Times New Roman;\"><\/span><\/span><span style=\"font-family:\u5b8b\u4f53;font-weight:bold;\">\u8870\u8001\u76f8\u5173lncRNA\u6807\u8bb0\u7684\u6784\u5efa<\/span><span style=\"font-family:Times New Roman;font-weight:bold;\"><\/span><\/section>\n<section style=\"margin-top: 0pt;margin-bottom: 0pt;text-align: justify;margin-left: 0pt;line-height: 22pt;font-size: 12pt;font-family: "Times New Roman";font-weight: normal;text-indent: 0em;\"><span style=\"font-family:\u5b8b\u4f53;\">\u4f5c\u8005<\/span><span style=\"font-family:\u5b8b\u4f53;\">\u7528LASSO\u56de\u5f52\u6765\u51cf\u5c11\u8fc7\u62df\u5408\uff0c\u5c06\u8870\u8001\u76f8\u5173lncRNA\u6570\u91cf\u51cf\u5c11\u81f320\u4e2a\uff08\u56fe1B\u3001C)\u3002\u901a\u8fc7\u591a\u53d8\u91cfCOX\u5206\u6790\u5efa\u7acb\u4e86\u75316\u4e2alncRNA\u7ec4\u6210\u7684\u98ce\u9669\u7279\u5f81\uff0c\u6839\u636e\u98ce\u9669\u8bc4\u5206\u516c\u5f0f\uff0c\u4f9d\u6b21\u5bf9TCGA-BRCA\u60a3\u8005\u8fdb\u884c\u98ce\u9669\u8bc4\u5206\u3002\u57fa\u4e8e\u98ce\u9669\u8bc4\u5206\u7684\u6700\u4f73X\u5206\u4f4d\u6570\u622a\u65ad\uff0c\u5c06\u8bad\u7ec3\u96c6\u5206\u4e3a\u4f4e\u98ce\u9669\u548c\u9ad8\u98ce\u9669\u7ec4\u3002\u56fe1F\u6240\u793a\u4e3a\u5728\u9ad8\u4f4e\u4e24\u4e2a\u98ce\u9669\u7ec4\u4e4b\u95f4\u4e0e\u8870\u8001\u76f8\u5173\u7684\u516d\u79cdlncRNA\u7684\u8868\u8fbe\u6a21\u5f0f\u3002\u5229\u7528Cytoscape 3.7.2\u8f6f\u4ef6\u5bf9\u8fd96\u4e2alncRNA\u4e0eBC\u8870\u8001\u76f8\u5173\u57fa\u56e0\u7684\u5171\u8868\u8fbe\u7f51\u7edc\u8fdb\u884c\u53ef\u89c6\u5316(\u56fe1E)\u3002\u6851\u57fa\u56fe\u663e\u793a\u4e86\u98ce\u9669\u7c7b\u578b\u3001\u4e0e\u8870\u8001\u76f8\u5173\u7684\u57fa\u56e0\u4ee5\u53ca\u4e0e\u8870\u8001\u76f8\u5173\u7684\u9884\u540elncRNA\u4e4b\u95f4\u7684\u76f8\u5173\u6027\uff08\u56fe1D\uff09\u3002\u6b64\u5916\uff0c\u901a\u8fc7ROC\u66f2\u7ebf\u8bc1\u660e\u4e86BC\u60a3\u8005\u9884\u540e\u98ce\u9669\u8bc4\u5206\u7684\u826f\u597d\u9884\u6d4b\u80fd\u529b\uff0c1\u30013\u548c5\u5e74\u7684AUC\u5206\u522b\u4e3a0.753\u30010.772\u548c0.722(\u56fe1G)\u3002<\/span><\/section>\n<section style=\"margin-top: 0pt;margin-bottom: 0pt;text-align: center;margin-left: 0pt;line-height: 22pt;font-size: 12pt;font-family: "Times New Roman";font-weight: normal;text-indent: 0em;\"><img decoding=\"async\" class=\"rich_pages wxw-img js_insertlocalimg\" data-ratio=\"0.9692622950819673\" data-s=\"300,640\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_5pBNwIqVeo0yXeURVzf9rO7CM3NJ9Q.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/o6dficDtnSUTzSzUtvljk46qYPfR4XVpP9QNUXbwOYoOEEgMv0CBECgBc5pBNwIqVeo0yXeURVzf9rO7CM3NJ9Q\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"976\" style=\"text-align: center;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;font-size: 17px;letter-spacing: 0.034em;height: auto !important;\" \/><span style=\"text-align: center;text-indent: 21pt;letter-spacing: 0.034em;font-size: 10.5pt;font-family: \u5b8b\u4f53;\">\u56fe1<\/span><span style=\"text-align: center;text-indent: 21pt;letter-spacing: 0.034em;font-size: 10.5pt;\"> <\/span><span style=\"text-align: center;text-indent: 21pt;letter-spacing: 0.034em;font-size: 10.5pt;font-family: \u5b8b\u4f53;\">\u6784\u5efa\u4e0e\u8870\u8001\u76f8\u5173\u7684lncRNA\u9884\u540e\u7279\u5f81<\/span><span style=\"font-size: 10.5pt;letter-spacing: 0.034em;text-indent: 21pt;\"><\/span><\/section>\n<section style=\"margin-left: 22pt;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-family:Times New Roman;font-weight:bold;\">2.<span style=\"font:7.0pt Times New Roman;\"><\/span><\/span><span style=\"font-family:\u5b8b\u4f53;font-weight:bold;\">\u8870\u8001\u76f8\u5173lncRNA\u6807\u8bb0\u7684\u9a8c\u8bc1<\/span><span style=\"font-family:Times New Roman;font-weight:bold;\"><\/span><\/section>\n<section style=\"margin-top: 0pt;margin-bottom: 0pt;text-align: justify;margin-left: 0pt;line-height: 22pt;font-size: 12pt;font-family: "Times New Roman";font-weight: normal;text-indent: 0em;\"><span style=\"font-family:\u5b8b\u4f53;\">\u4e3a\u4e86<\/span><span style=\"font-family:\u5b8b\u4f53;\">\u8bc1\u660e\u8870\u8001\u76f8\u5173lncRNA\u7279\u5f81\u7684\u51c6\u786e\u6027\uff0c\u7ed9\u4e88\u6d4b\u8bd5\u961f\u5217\u4e2d\u7684\u6bcf\u4e00\u4f4d\u60a3\u8005\u98ce\u9669\u8bc4\u5206\u3002\u7136\u540e\u5c06\u6d4b\u8bd5\u961f\u5217\u60a3\u8005\u6309\u7167\u76f8\u540c\u7684\u622a\u65ad\u503c\u5206\u4e3a\u4e24\u4e2a\u4e0d\u540c\u7684\u98ce\u9669\u4e9a\u7ec4(\u56fe2A, B)\u3002Kaplan-Meier\u68c0\u9a8c\u663e\u793a\uff0c\u4e0e\u4f4e\u98ce\u9669\u4e9a\u7ec4\u76f8\u6bd4\uff0c\u9ad8\u98ce\u9669\u4e9a\u7ec4\u7684OS\u660e\u663e\u964d\u4f4e(\u56fe2C-E)\u3002ROC\u66f2\u7ebf(\u56fe2F-H)\u9a8c\u8bc1\u4e86\u8870\u8001\u76f8\u5173lncRNA\u6807\u7b7e\u9884\u6d4b\u9884\u540e\u7684\u53ef\u9760\u6027\u3002<\/span><span style=\"font-family:Times New Roman;\"><\/span><\/section>\n<p style=\"text-align: center;margin-bottom: 24px;\"><img decoding=\"async\" class=\"rich_pages wxw-img js_insertlocalimg\" data-ratio=\"1.0697424892703862\" data-s=\"300,640\" data-type=\"png\" data-w=\"932\" style=\"height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_RRohoRFJZgh6vFxbr2qCFwJpHl9PJA.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/o6dficDtnSUTzSzUtvljk46qYPfR4XVpPESkfRtdRatMAbJXnXM1smZCZRRohoRFJZgh6vFxbr2qCFwJpHl9PJA\/640?wx_fmt=png'\" \/><span style=\"text-indent: 21pt;letter-spacing: 0.034em;font-size: 10.5pt;font-family: \u5b8b\u4f53;\">\u56fe2<\/span><span style=\"font-family: "Times New Roman";text-indent: 21pt;letter-spacing: 0.034em;font-size: 10.5pt;\"> <\/span><span style=\"text-indent: 21pt;letter-spacing: 0.034em;font-size: 10.5pt;font-family: \u5b8b\u4f53;\">\u9a8c\u8bc1\u4e0e\u8870\u8001\u76f8\u5173\u7684lncRNA\u9884\u540e\u7279\u5f81<\/span><\/p>\n<section style=\"margin-left: 22pt;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-family:Times New Roman;font-weight:bold;\">3.<span style=\"font:7.0pt Times New Roman;\"><\/span><\/span><span style=\"font-family:Times New Roman;font-weight:bold;\">BC\u60a3\u8005\u5217\u7ebf\u56fe\u7684\u6784\u5efa<\/span><span style=\"font-family:Times New Roman;font-weight:bold;\"><\/span><\/section>\n<section style=\"margin-top: 0pt;margin-bottom: 0pt;text-align: justify;margin-left: 0pt;line-height: 22pt;font-size: 12pt;font-family: "Times New Roman";font-weight: normal;text-indent: 0em;\"><span style=\"font-family:\u5b8b\u4f53;\">\u6839\u636e<\/span><span style=\"font-family:\u5b8b\u4f53;\">\u5355\u56e0\u7d20Cox\u56de\u5f52\u5206\u6790\uff0c\u98ce\u9669\u8bc4\u5206\u662fBC\u60a3\u8005\u7684\u9884\u540e\u6307\u6807\uff08\u56fe3A\uff09\u3002ROC\u66f2\u7ebf\u8868\u660e\uff0c\u4e0e\u5176\u4ed6\u4e34\u5e8a\u7279\u5f81\u76f8\u6bd4\uff0c1\u5e74\u30013\u5e74\u548c5\u5e74\u98ce\u9669\u8bc4\u5206\u7684AUS\u5206\u522b\u8fbe\u52300.713\u30010.707\u548c0.673\uff08\u56fe3C-E\uff09\u3002\u4e3a\u4e86\u8fdb\u4e00\u6b65\u63d0\u9ad8\u8870\u8001\u76f8\u5173lncRNA\u6807\u8bb0\u7684\u4e34\u5e8a\u5e94\u7528\uff0c\u4f5c\u8005\u8fd8\u5f62\u6210\u4e86\u4e00\u79cd\u65b0\u7684\u5217\u7ebf\u56fe\uff0c\u5c06\u4e34\u5e8a\u75c5\u7406\u5b66\u4fe1\u606f\u4e0e\u98ce\u9669\u8bc4\u5206\u76f8\u7ed3\u5408\uff0c\u4ee5\u9884\u6d4bBC\u60a3\u80051\u5e74\uff0c3\u5e74\u548c5\u5e74\u7684OS\uff08\u56fe3F\uff09\u3002\u5217\u7ebf\u56fe\u4e2d1\u5e74\u30013\u5e74\u548c5\u5e74OS\u7684\u9884\u6d4b\u53ef\u80fd\u6027\u4e0e\u5b9e\u9645\u89c2\u5bdf\u7ed3\u679c\u4e00\u81f4\uff08\u56fe3G\uff09\u3002\u8be5\u5217\u7ebf\u56fe\u5728\u9884\u6d4b\u4e34\u5e8a\u7ed3\u679c\u65b9\u9762\u5177\u6709\u4ee4\u4eba\u4fe1\u670d\u7684\u7279\u5f02\u6027\u548c\u654f\u611f\u6027\u3002\u4e0e\u4f20\u7edf\u7684\u4e34\u5e8a\u75c5\u7406\u5b66\u7279\u5f81\u76f8\u6bd4\uff0c\u5217\u7ebf\u56fe\u5177\u6709\u6700\u4f73\u7684\u9884\u6d4b\u51c0\u6548\u76ca\uff08\u56fe3I\uff09\uff0c\u4e0a\u8ff0\u7ed3\u679c\u8868\u660e\uff0c\u4e3a\u4e86\u5728\u4e34\u5e8a\u4e0a\u9884\u6d4bBC\u60a3\u8005\u7684\u9884\u540e\uff0c\u5217\u7ebf\u56fe\u662f\u5408\u9002\u7684\u3002<\/span><span style=\"font-family:Times New Roman;\"><\/span><\/section>\n<p style=\"text-align: center;margin-bottom: 24px;\"><img decoding=\"async\" class=\"rich_pages wxw-img js_insertlocalimg\" data-ratio=\"0.8629629629629629\" data-s=\"300,640\" data-type=\"png\" data-w=\"1080\" style=\"height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_BKDLG7ic4VAthn5rB7aq1ic9fcxHLA.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/o6dficDtnSUTzSzUtvljk46qYPfR4XVpPDHibY03EtVr2TuQ0Q9UUdpTq62QBKDLG7ic4VAthn5rB7aq1ic9fcxHLA\/640?wx_fmt=png'\" \/><span style=\"text-indent: 21pt;letter-spacing: 0.034em;font-size: 10.5pt;font-family: \u5b8b\u4f53;\">\u56fe<\/span><span style=\"font-family: "Times New Roman";text-indent: 21pt;letter-spacing: 0.034em;font-size: 10.5pt;\">3 \u7528\u4e8e\u751f\u5b58\u9884\u6d4b\u7684\u4e34\u5e8a\u9884\u540e\u5217\u7ebf\u56fe\u7684\u6784\u5efa\u548c\u9a8c\u8bc1<\/span><\/p>\n<section style=\"margin-left: 22pt;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-family:Times New Roman;font-weight:bold;\">4.<span style=\"font:7.0pt Times New Roman;\"><\/span><\/span><span style=\"font-family:\u5b8b\u4f53;font-weight:bold;\">\u98ce\u9669\u8bc4\u5206\u4e0e\u4e34\u5e8a\u75c5\u7406\u7279\u5f81\u7684\u76f8\u5173\u6027<\/span><span style=\"font-family:Times New Roman;font-weight:bold;\"><\/span><\/section>\n<section style=\"margin-top: 0pt;margin-bottom: 0pt;margin-left: 0pt;line-height: 22pt;font-size: 12pt;font-family: "Times New Roman";font-weight: normal;text-align: justify;text-indent: 0em;\"><span style=\"font-family:\u5b8b\u4f53;\">\u4f5c\u8005<\/span><span style=\"font-family:\u5b8b\u4f53;\">\u8bc4\u4f30\u4e86BC\u60a3\u8005\u7684\u98ce\u9669\u8bc4\u5206\u4e0e\u4e34\u5e8a\u75c5\u7406\u7279\u5f81\u4e4b\u95f4\u7684\u76f8\u5173\u6027\u3002\u4f4e\u98ce\u9669\u7ec4\u9ad8\u8868\u8fbeMCF2L-AS1\uff0cMAPT-AS1\uff0cUSP30-AS1\uff0cPRR34-AS1\u548cDLGAP1-AS1\uff0c\u800c\u9ad8\u98ce\u9669\u7ec4\u9ad8\u8868\u8fbeOTUD6B-AS1\uff0c\u5982\u70ed\u56fe\u6240\u793a\uff08\u56fe4A\uff09\u3002\u98ce\u9669\u8bc4\u5206\u663e\u793aBC\u60a3\u8005\u4e0d\u540c\u4e34\u5e8a\u75c5\u7406\u7279\u5f81\u7684\u5206\u5e03\u6a21\u5f0f\u4e0d\u540c\uff0c\u6d89\u53caTNM\u5206\u671f\u3001\u751f\u5b58\u72b6\u6001\u3001\u5e74\u9f84\u548c\u4e34\u5e8a\u5206\u671f\uff08\u56fe4B\uff0cC\uff09\u3002\u4f5c\u8005\u8fd8\u5bf9\u4e0d\u540c\u4e34\u5e8a\u7279\u5f81\u4e9a\u7ec4\u7684\u8870\u8001\u7279\u5f81\u8fdb\u884c\u4e86\u751f\u5b58\u5206\u6790\u3002BC\u60a3\u8005\u5728\u4f4e\u5371\u7ec4\u7684\u5e74\u9f84\u3001M\u5206\u671f\u3001T\u5206\u671f\u548c\u4e34\u5e8a\u5206\u671f\u7684\u751f\u5b58\u6982\u7387\u8f83\u9ad8\u3002\u603b\u4f53\u800c\u8a00\uff0c\u8870\u8001\u76f8\u5173\u6a21\u578b\u4e0e\u4e34\u5e8a\u7279\u5f81\u5bc6\u5207\u76f8\u5173\uff0c\u5e76\u4e14\u80fd\u591f\u9884\u6d4b\u5177\u6709\u4e0d\u540c\u4e34\u5e8a\u7279\u5f81\u7684BC\u60a3\u8005\u7684\u751f\u5b58\u7387\uff08\u56fe4D-J\uff09\u3002\u4f7f\u7528Kaplan-Meier\u66f2\u7ebf\u8bc4\u4f306\u4e2alncRNA\u5728\u4e73\u817a\u764c\u60a3\u8005\u9884\u540e\u4e2d\u7684\u8868\u8fbe\u4e0e\u6211\u4eec\u7684\u98ce\u9669\u6a21\u578b\u4e4b\u95f4\u7684\u8054\u7cfb\u3002\u5728BC\u60a3\u8005\u4e2d\uff0c\u53ea\u6709OTUD6B-AS1\u7684\u9ad8\u8868\u8fbe\u4e0e\u4e0d\u826f\u9884\u540e\u76f8\u5173\uff0c\u800c\u5728BC\u60a3\u8005\u4e2d\uff0c\u5176\u4ed65\u4e2alncRNA\u7684\u9ad8\u8868\u8fbe\u4e0e\u826f\u597d\u9884\u540e(\u56fe4K-P)\u76f8<\/span><span style=\"font-family:Times New Roman;\">\u5173\u3002<\/span><span style=\"font-family:Times New Roman;\"><\/span><\/section>\n<p style=\"text-align: center;margin-bottom: 24px;\"><img decoding=\"async\" class=\"rich_pages wxw-img js_insertlocalimg\" data-ratio=\"1.2215962441314554\" data-s=\"300,640\" data-type=\"png\" data-w=\"1065\" style=\"height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_T6lY7BSiczIylMLO0BlSQwUiaicp6A.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/o6dficDtnSUTzSzUtvljk46qYPfR4XVpPJEonO7uQufFStTFytPzPuzkpSdPT6lY7BSiczIylMLO0BlSQwUiaicp6A\/640?wx_fmt=png'\" \/><span style=\"text-indent: 21pt;letter-spacing: 0.034em;font-size: 10.5pt;font-family: \u5b8b\u4f53;\">\u56fe<\/span><span style=\"font-family: "Times New Roman";text-indent: 21pt;letter-spacing: 0.034em;font-size: 10.5pt;\">4 <\/span><span style=\"text-indent: 21pt;letter-spacing: 0.034em;font-size: 10.5pt;font-family: \u5b8b\u4f53;\">\u98ce\u9669\u8bc4\u5206\u4e0e\u4e34\u5e8a\u75c5\u7406\u7279\u5f81\u4e4b\u95f4\u7684\u5173\u7cfb<\/span><span style=\"font-family: "Times New Roman";font-size: 10.5pt;text-indent: 21pt;letter-spacing: 0.034em;\"><\/span><\/p>\n<section style=\"margin-left: 22pt;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-family:Times New Roman;font-weight:bold;\">5.<span style=\"font:7.0pt Times New Roman;\"><\/span><\/span><span style=\"font-family:\u5b8b\u4f53;font-weight:bold;\">\u514d\u75ab\u7ec6\u80de\u6d78\u6da6\u5206\u6790<\/span><span style=\"font-family:Times New Roman;font-weight:bold;\"><\/span><\/section>\n<section style=\"margin-top: 0pt;margin-bottom: 0pt;text-align: justify;margin-left: 0pt;line-height: 22pt;font-size: 12pt;font-family: "Times New Roman";font-weight: normal;text-indent: 0em;\"><span style=\"font-family:\u5b8b\u4f53;\">\u540e\u9762<\/span><span style=\"font-family:\u5b8b\u4f53;\">\u8fdb\u4e00\u6b65\u63a2\u8ba8\u8870\u8001\u76f8\u5173\u7684lncRNA\u6807\u8bb0\u662f\u5426\u4e0e\u80bf\u7624\u514d\u75ab\u6709\u5173\u3002\u4f5c\u8005\u53d1\u73b0\uff0c\u5728\u9ad8\u4f4e\u4e24\u4e2a\u98ce\u9669\u7ec4\u4e2d\u7684\u80bf\u7624\u6d78\u6da6\u514d\u75ab\u7ec6\u80de\u7684\u5bcc\u96c6\u5b58\u5728\u660e\u663e\u5dee\u5f02\uff0c\u5982\u56fe5B\u6240\u793a\u3002\u56fe5C\uff0cD\u8868\u660e\u9759\u606fNK\u7ec6\u80de\u3001M2\u5de8\u566c\u7ec6\u80de\u548cM0\u5de8\u566c\u7ec6\u80de\u4e0e\u98ce\u9669\u8bc4\u5206\u5448\u6b63\u76f8\u5173\u3002\u6d46\u7ec6\u80de\u3001B\u8bb0\u5fc6\u7ec6\u80de\u3001\u5355\u6838\u7ec6\u80de\u3001\u6d3b\u5316\u7684NK\u7ec6\u80de\u3001\u9759\u606f\u80a5\u5927\u7ec6\u80de\u3001\u8c03\u8282\u6027T\u7ec6\u80de\u548cCD8+T\u7ec6\u80de\u5747\u4e0e\u98ce\u9669\u8bc4\u5206\u5448\u8d1f\u76f8\u5173\u3002\u540c\u65f6\uff0c\u6839\u636e\u76ae\u5c14\u900a\u76f8\u5173\u6027\u5206\u6790\uff0c\u516b\u4e2a\u514d\u75ab\u7ec6\u80de\u4e0e\u98ce\u9669\u8bc4\u5206\u663e\u7740\u76f8\u5173\uff08\u56fe5E-L\uff09\u3002\u7ed3\u679c\u8868\u660e\uff0c\u98ce\u9669\u6a21\u578b\u4e2d\u76846\u79cdlncRNA\u53ef\u4ee5\u533a\u5206BC\u4e2d\u514d\u75ab\u7ec6\u80de\u6d78\u6da6\u7684\u4e0d\u540c\u7279\u5f81\u3002<\/span><span style=\"font-family:Times New Roman;\"><\/span><\/section>\n<p style=\"text-align: center;margin-bottom: 24px;\"><img decoding=\"async\" class=\"rich_pages wxw-img js_insertlocalimg\" data-ratio=\"1.1898148148148149\" data-s=\"300,640\" data-type=\"png\" data-w=\"1080\" style=\"height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_QZHoZCKLVGeS9xfnhYrxxwW646nLFg.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/o6dficDtnSUTzSzUtvljk46qYPfR4XVpPNBRE6xGX4ibRHqCE1Y70f69NFQZHoZCKLVGeS9xfnhYrxxwW646nLFg\/640?wx_fmt=png'\" \/><span style=\"text-indent: 21pt;letter-spacing: 0.034em;font-size: 10.5pt;font-family: \u5b8b\u4f53;\">\u56fe<\/span><span style=\"font-family: "Times New Roman";text-indent: 21pt;letter-spacing: 0.034em;font-size: 10.5pt;\">5 <\/span><span style=\"text-indent: 21pt;letter-spacing: 0.034em;font-size: 10.5pt;font-family: \u5b8b\u4f53;\">\u514d\u75ab\u68c0\u67e5\u70b9\u5206\u5b50\u7684\u8868\u8fbe\u4ee5\u53ca\u98ce\u9669\u8bc4\u5206\u4e0e\u514d\u75ab\u7ec6\u80de\u6d78\u6da6\u5728\u4e24\u4e2a\u4e0d\u540c\u98ce\u9669\u7ec4\u4e2d\u7684\u5173\u7cfb<\/span><\/p>\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\" style=\"margin-bottom: 24px;\">\n<section style=\"display: flex;flex-direction: column;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"display: flex;flex-direction: column;align-self: center;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"border-width: 1px;border-style: solid;border-color: rgb(74, 74, 74);padding: 0px 5px;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"display: flex;justify-content: center;align-items: center;padding: 6px 8px;background: #F6801F;border-left: 1px solid #4A4A4A;border-right: 1px solid #4A4A4A;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"width: 20px;height: 15px;display: flex;justify-content: center;align-items: center;flex-shrink: 0;\" data-mid=\"\" mpa-from-tpl=\"t\"><br \/><\/section>\n<section style=\"min-width: 100px;text-align: center;padding: 0 8px;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<p style=\"font-size: 16px;font-weight: bold;color: #FFFFFF;line-height: 22px;word-break: break-word;\" data-mid=\"\" mpa-is-content=\"t\">\u603b\u7ed3<\/p>\n<\/section>\n<section style=\"width: 20px;height: 15px;display: flex;justify-content: center;align-items: center;flex-shrink: 0;transform: rotateY(180deg);\" data-mid=\"\" mpa-from-tpl=\"t\"><br \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"mso-style-parent: '';margin-top: 0.0pt;margin-bottom: 0.0pt;text-align: justify;text-justify: inter-ideograph;margin-left: 0.0pt;text-indent: 0.0pt;line-height: 22.0pt;font-size: 12.0pt;font-family: Times New Roman;font-weight: normal;\"><span style=\"font-family: \u5b8b\u4f53;font-size: 12pt;text-indent: 24pt;letter-spacing: 0.034em;caret-color: transparent;\">\u867d\u7136\u6587\u7ae0\u7684\u5206\u6790\u601d\u8def\u6bd4\u8f83\u7b80\u5355\uff0c\u4f46\u662f\u9009\u9898\u6bd4\u8f83\u65b0\u9896\uff0c\u4e5f\u53ef\u4ee5\u8f7b\u677e\u53d1\u5230\u5c06\u8fd1\u4e94\u5206\u7684\u6587\u7ae0\uff01<\/span><span style=\"font-family: \u5b8b\u4f53;font-size: 12pt;text-indent: 24pt;letter-spacing: 0.034em;caret-color: transparent;\">\u4f5c\u8005\u521b\u5efa\u4e86\u4e00\u4e2a\u5168\u65b0\u7684lncRNA\u8870\u8001\u9884\u6d4b\u7279\u5f81\uff0c\u5e76\u6709\u53ef\u80fd\u6210\u4e3a\u4fb5\u88ad\u6027BC\u60a3\u8005\u7684\u9884\u6d4b\u751f\u7269\u6807\u5fd7\u7269\u3002<\/span><span style=\"font-family: \u5b8b\u4f53;font-size: 12pt;text-indent: 24pt;letter-spacing: 0.034em;caret-color: transparent;\">\u4f5c\u8005\u6784\u5efa\u4e86\u5305\u62ec2\u79cdlncRNA\u5206\u5b50\u7684\u8870\u8001\u76f8\u5173lncRNA\u7684\u9884\u540e\u6a21\u578b\uff0c\u4e3aBC\u7684\u65e9\u671f\u8bca\u65ad\u548c\u6cbb\u7597\u9776\u70b9\u8bc6\u522b\uff08\u5305\u62ec\u80bf\u7624\u514d\u75ab\u6cbb\u7597\uff09\u63d0\u4f9b\u65b0\u7684\u89c6\u89d2\u548c\u65b9\u6cd5\u3002<\/span><span style=\"font-family: \u5b8b\u4f53;font-size: 12pt;text-indent: 24pt;letter-spacing: 0.034em;caret-color: transparent;\">\u6240\u4ee5\u9009\u5bf9\u5206\u6790\u65b9\u5411\u3001\u5de7\u5999\u7684\u601d\u8def\u662f\u53d1\u6587\u7684\u795e\u5668\uff01<\/span><span style=\"font-family: \u5b8b\u4f53;font-size: 12pt;text-indent: 24pt;letter-spacing: 0.034em;caret-color: transparent;\">\u770b\u4e86\u8fd9\u7bc7\u6587\u7ae0\u4e4b\u540e\uff0c\u4f60\u662f\u5426\u53c8\u6709\u4e86\u751f\u4fe1\u65b0\u601d\u8def\uff1f<\/span><span style=\"font-family: \u5b8b\u4f53;font-size: 12pt;text-indent: 24pt;letter-spacing: 0.034em;caret-color: transparent;\">\u7b80\u5355\u7684\u9884\u540e\u6a21\u578b\u6784\u5efa\u4e0e\u9a8c\u8bc1\u4f1a\u7ed9\u4f60\u5e26\u6765\u4e0d\u4e00\u6837\u7684\u60ca\u559c\uff0c\u66f4\u591a\u8be6\u60c5\u8bf7\u5173\u6ce8\u5e03\u5c0f\u8c37\uff0c\u6587\u7ae0\u521b\u65b0\u4e0d\u8ff7\u8def\uff01<\/span><span style=\"font-size: 12pt;text-indent: 24pt;letter-spacing: 0.034em;\"><\/span><\/p>\n<p style=\"mso-style-parent: '';margin-top: 0.0pt;margin-bottom: 0.0pt;text-justify: inter-ideograph;margin-left: 0.0pt;font-size: 12.0pt;font-family: Times New Roman;font-weight: normal;text-align: center;text-indent: 24.0pt;line-height: 150%;\"><span style=\"font-family:\u5b8b\u4f53;font-weight:bold;\"><\/span><br mpa-from-tpl=\"t\" \/><\/p>\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\" style=\"margin-bottom: 24px;\">\n<section style=\"width: 100%;padding: 0 8px;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"width: 100%;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"width: 100%;border-width: 1px;border-style: solid;border-color: rgb(74, 74, 74);padding: 0px 5px;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"width: 100%;padding: 13px 10px;background: #F6801F;border-left: 1px solid #4A4A4A;border-right: 1px solid #4A4A4A;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"display: flex;justify-content: center;align-items: center;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<section style=\"width: 20px;height: 15px;display: flex;justify-content: center;align-items: center;flex-shrink: 0;\" data-mid=\"\" mpa-from-tpl=\"t\"><br \/><\/section>\n<section style=\"min-width: 100px;text-align: center;padding: 0 8px;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<p style=\"font-size: 16px;font-weight: bold;color: rgb(255, 255, 255);line-height: 22px;word-break: break-word;text-align: center;\" data-mid=\"\" mpa-is-content=\"t\"><span style=\"font-size: 18px;\">\u5e03\u5c0f\u8c37\u4e4b\u58f0<\/span><\/p>\n<\/section>\n<section style=\"width: 20px;height: 15px;display: flex;justify-content: center;align-items: center;flex-shrink: 0;transform: rotateY(180deg);\" data-mid=\"\" mpa-from-tpl=\"t\"><br \/><\/section>\n<\/section>\n<section style=\"width: 100%;text-align: left;padding: 9px 0 0 0;\" data-mid=\"\" mpa-from-tpl=\"t\">\n<p style=\"font-size: 14px;color: rgb(255, 255, 255);line-height: 26px;word-break: break-word;text-align: center;\" data-mid=\"\" mpa-is-content=\"t\">\u5982\u679c\u60a8\u7684\u65f6\u95f4\u548c\u7cbe\u529b\u6709\u9650\u6216\u8005\u7f3a\u4e4f\u76f8\u5173\u7ecf\u9a8c\uff0c\u5e76\u4e14\u5bf9\u751f\u4fe1\u5206\u6790\u548c\u601d\u8def\u8bbe\u8ba1\u6709\u6240\u9700\u8981\u7684\u8bdd\uff0c\u201c\u751f\u4fe1\u9e1f\u201d\u975e\u5e38\u4e50\u610f\u4e3a\u60a8\u63d0\u4f9b\u5982\u4e0b\u670d\u52a1\uff1a\u514d\u8d39\u601d\u8def\u8bc4\u4f30\u3001\u4ed8\u8d39\u751f\u4fe1\u5206\u6790\u548c\u65b9\u6848\u8bbe\u8ba1\u4ee5\u53ca\u5b9e\u9a8c\u9879\u76ee\u5b9e\u65bd\u7b49\uff0c\u6709\u610f\u5411\u7684\u5c0f\u4f19\u4f34\u6b22\u8fce\u54a8\u8be2\u5e03\u5c0f\u8c37\u54e6\uff01<\/p>\n<p style=\"font-size: 14px;color: rgb(255, 255, 255);line-height: 26px;word-break: break-word;text-align: center;\" data-mid=\"\" mpa-is-content=\"t\"><br \/><\/p>\n<p style=\"font-size: 14px;color: rgb(255, 255, 255);line-height: 26px;word-break: break-word;text-align: center;\" data-mid=\"\" mpa-is-content=\"t\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"1\" data-w=\"158\" style=\"width: 158px;height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_1vmciaJr3uiaJdcqS1EoePIo9VIgRQ.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/o6dficDtnSUQxc4MxhXeZqEnnDktZfic68cwSU979xNLwrCtNguUufQXaMwG1vmciaJr3uiaJdcqS1EoePIo9VIgRQ\/640?wx_fmt=png'\" \/><\/p>\n<p style=\"font-size: 14px;color: rgb(255, 255, 255);line-height: 26px;word-break: break-word;text-align: center;\" data-mid=\"\" mpa-is-content=\"t\">\u626b\u7801\u54a8\u8be2\u5e03\u5c0f\u8c37\u5427<\/p>\n<p style=\"font-size: 14px;color: rgb(255, 255, 255);line-height: 26px;word-break: break-word;text-align: center;\" data-mid=\"\" mpa-is-content=\"t\"><br \/><\/p>\n<p style=\"font-size: 14px;color: rgb(255, 255, 255);line-height: 26px;word-break: break-word;text-align: center;\" data-mid=\"\" mpa-is-content=\"t\"><span style=\"font-size: 18px;\">\u5f80\u671f\u63a8\u8350<\/span><\/p>\n<p style=\"font-size: 14px;color: rgb(255, 255, 255);line-height: 26px;word-break: break-word;text-align: justify;\" data-mid=\"\" mpa-is-content=\"t\">1. <a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkzMzQzNDMzMg==&mid=2247498128&idx=1&sn=3704599b51792828723d9929038d53bf&chksm=c24e3f23f539b6358c8c330dabf002d007a43ce25b3d77b6139300391b3099a914893e46cc22&scene=21#wechat_redirect\" data-linktype=\"2\">4\u5f20\u56fe\u62ff\u4e0b5.9\u5206+\u7eaf\u6570\u636e\u6316\u6398\u6587\u7ae0\uff1f\u4f60\u6ca1\u542c\u9519\uff01\u4e34\u5e8aSEER\u516c\u5171\u6570\u636e\u5e93\u8d85\u7b80\u5355\u5206\u6790\u601d\u8def\uff0c\u5e26\u4f60\u5b9e\u73b0\u6362\u9053\u8d85\u8f66\uff01<\/a><\/p>\n<p style=\"font-size: 14px;color: rgb(255, 255, 255);line-height: 26px;word-break: break-word;text-align: justify;\" data-mid=\"\" mpa-is-content=\"t\">2. <a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkzMzQzNDMzMg==&mid=2247498127&idx=1&sn=4776c81230d5ab39b20a5289585b90cf&chksm=c24e3f3cf539b62ae58685a5103552def6130543502ee77bb504c80fa792205b4d4c59dfda55&scene=21#wechat_redirect\" data-linktype=\"2\">\u591a\u7ec4\u5b66+\u5355\u7ec6\u80de\u5206\u6790+\u514d\u75ab\u68c0\u67e5\u70b9\uff0c\u6cdb\u764c\u5206\u6790\u4e5f\u80fd\u82b1\u6837\u767e\u51fa\uff0c\u4e24\u4e2a\u6708\u8f7b\u677e\u62ff\u4e0b6\u5206+\uff0c\u65b0\u601d\u8def\u4e0d\u5bb9\u9519\u8fc7\uff01<\/a><\/p>\n<p style=\"font-size: 14px;color: rgb(255, 255, 255);line-height: 26px;word-break: break-word;text-align: justify;\" data-mid=\"\" mpa-is-content=\"t\">3.  <a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkzMzQzNDMzMg==&mid=2247497213&idx=1&sn=bbd3867e8b00f5806f02080aa4f0adef&chksm=c24e334ef539ba58b2db883ed83121de54828ea9abf0e940e38ce5f8793f2f965712120fffaa&scene=21#wechat_redirect\" data-linktype=\"2\">3\u5206+\u751f\u4fe1\u8001\u724c\u671f\u520a\uff0c\u63a5\u53d7\u7eaf\u751f\u4fe1\uff0c\u4e2d\u79d1\u96624\u533a\uff0c\u975e\u9884\u8b66\uff0c\u6536\u7a3f\u8303\u56f4\u5e7f\uff0c\u63a5\u53d7\u7387\u9ad8\uff0c\u653e\u5fc3\u6295\uff01<\/a><\/p>\n<p style=\"font-size: 14px;color: rgb(255, 255, 255);line-height: 26px;word-break: break-word;text-align: justify;\" data-mid=\"\" mpa-is-content=\"t\">4.<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkzMzQzNDMzMg==&mid=2247497211&idx=1&sn=a8ff77aa8f66fe7c372f46bb8855c75b&chksm=c24e3348f539ba5e6e3ea4a184dafb04511e625541efb4d07255927a95c772450507c3352cf1&scene=21#wechat_redirect\" data-linktype=\"2\">\u201c\u65b0\u51a0\u201d\u518d\u6380\u6ce2\u6f9c\uff01\u72ec\u5bb6\u76d8\u70b96\u4e2a\u79d1\u7814\u5fc5\u5907\u3010\u65b0\u51a0\u6570\u636e\u5e93\u3011\uff0c\u5feb\u7801\u4f4f\uff0c\u8d81\u7740\u751f\u4fe1\u7814\u7a76\u70ed\u6f6e\uff0c\u901f\u901f\u4e0a\u8f66\uff01<\/a><\/p>\n<p style=\"font-size: 14px;color: #FFFFFF;line-height: 26px;word-break: break-word;\" data-mid=\"\" mpa-is-content=\"t\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.5555555555555556\" data-w=\"900\" style=\"font-family: PingFangSC-Regular, "PingFang SC";font-size: 14px;letter-spacing: 0.578px;text-align: left;white-space: normal;background-color: rgba(223, 243, 229, 0.88);color: rgb(79, 147, 3);height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_tcZK6DztQUVMRQrGXYJfAkAyHByh2Q.jpg\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/mmbiz_jpg\/o6dficDtnSURvmHVlv2g7DyHeEib1Liahep62oy1rE1WuRwrx3X7QkzdnkTtcZK6DztQUVMRQrGXYJfAkAyHByh2Q\/640?wx_fmt=jpeg'\" \/><\/p>\n<p style=\"font-size: 14px;color: rgb(255, 255, 255);line-height: 26px;word-break: break-word;text-align: left;\" data-mid=\"\" mpa-is-content=\"t\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwNjE0MDY3MQ==&mid=2650755322&idx=1&sn=3588f012f6d4a8c9ccf7c6550c6f1754&scene=21#wechat_redirect\" 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