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flex-start;display: flex;flex-flow: row nowrap;\">\n<section style=\"display: inline-block;width: 403.391px;vertical-align: top;align-self: flex-start;flex: 0 0 auto;height: auto;\">\n<section style=\"margin-top: 10px;\">\n<section style=\"text-align: center;\">\n<section style=\"font-size: 16px;\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;\">\n<section style=\"display: inline-block;vertical-align: top;width: 70.0348%;align-self: flex-start;flex: 0 0 auto;height: auto;max-width: 70.0348% !important;\">\n<section style=\"margin-top: 10px;\" powered-by=\"xiumi.us\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"text-align: center;\">\n<p style=\"text-indent: 0em;line-height: 1.75em;\"><span style=\"letter-spacing: 0.5px;\"><strong><span style=\"font-size: 15px;\">\u751f\u4fe1\u4ebaR\u8bed\u8a00\u5b66\u4e60\u5fc5\u5907<\/span><\/strong><\/span><\/p>\n<p 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0;\">\n<section>\n<section style=\"display: inline-block;vertical-align: middle;\" powered-by=\"xiumi.us\">\n<section style=\"line-height: 0;\">\n<section style=\"width: 111px;\" powered-by=\"xiumi.us\">\n<section style=\"line-height: 1.75em;text-indent: 0em;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;height: auto;width: 111px;\"><img decoding=\"async\" data-ratio=\"1\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_GBhsibRAgNiaQsH4ichdP9ibEhHMFA-77.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyL6u7wJswOp8vtpzGp6vYngnlT6jiavu08Bvp2iblzGf3IkoBD9NGBhsibRAgNiaQsH4ichdP9ibEhHMFA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"400\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-indent: 0em;line-height: 1.75em;\"><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section data-role=\"list\">\n<section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 8px;text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;\">\n<section style=\"padding-left: 8px;display: inline-block;width: 578px;vertical-align: top;border-left: 3px solid rgb(219, 219, 219);border-bottom-left-radius: 0px;align-self: flex-start;flex: 0 0 auto;\">\n<section powered-by=\"xiumi.us\" style=\"color: rgba(0, 0, 0, 0.5);text-align: justify;\">\n<p><span style=\"font-size: 14px;letter-spacing: 0.578px;\">\u76f8\u4fe1\u5f88\u591a\u533b\u5b66\u76f8\u5173\u7684\u5de5\u4f5c\u8005\u7ecf\u5e38\u82e6\u607c\u4e8eDrLink\u7684\u5b89\u88c5\uff0c\u56e0\u4e3a\u7f51\u4e0a\u7684\u8d44\u6e90\u5b9e\u5728\u662f\u592a\u5c11\u592a\u5c11\u4e86\uff0c\u9664\u4e86\u4e00\u4e2agithub\u4e3b\u9875\u5c31\u662f\u4e00\u7bc7\u6587\u732e\uff0c\u7ecf\u5e38\u6709\u5c0f\u767d\u5b89\u88c5\u62a5\u9519\u65e0\u4ece\u4e0b\u624b\uff0c\u522b\u62c5\u5fc3\uff0c\u4eca\u5929\u4e00\u7bc7\u6587\u7ae0\u6559\u4f60\u5b66\u4f1a\u3002<\/span><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section powered-by=\"xiumi.us\">\n<p style=\"text-align: center;\"><br \/><\/p>\n<section style=\"font-size: 16px;\">\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;white-space: normal;\"><strong><em><span style=\"font-size: 20px;\">DrLink<\/span><\/em><\/strong><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u5b83\u662f\u4e00\u4e2a\u4e0e\u57fa\u56e0\u7ec4\u91cd\u7ec4\u6709\u5173\u7684\u8f6f\u4ef6\uff0c\u5b83\u4f7f\u7528Linked-read\u6d4b\u5e8f\u68c0\u6d4b\u91cd\u7ec4\u65ad\u70b9\u3002\u5b98\u65b9gitHub\u4e2d\u663e\u793a\uff0c\u5b83\u662f\u4e00\u4e2a\u5173\u4e8eDetecting recombination breakpoints using Linked read sequencing\u7684\u8f6f\u4ef6\u3002\u5728\u8fd9\u4e2a\u77ed\u8bed\u4e2d\uff0c\u201cDetecting\u201d\u610f\u5473\u7740\u68c0\u6d4b\u6216\u53d1\u73b0\uff0c\u201crecombination breakpoints\u201d\u6307\u7684\u662f\u57fa\u56e0\u7ec4DNA\u5e8f\u5217\u4e2d\u91cd\u7ec4\u53d1\u751f\u7684\u4f4d\u7f6e\uff0c\u201cLinked-read sequencing\u201d\u662f\u4e00\u79cd\u6d4b\u5e8f\u6280\u672f\uff0c\u5b83\u53ef\u4ee5\u5145\u5206\u5229\u7528\u6761\u5f62\u7801\u6807\u8bb0\u6765\u89e3\u6790\u57fa\u56e0\u7ec4\u533a\u57df\uff0c\u5e76\u66f4\u51c6\u786e\u5730\u786e\u5b9a\u91cd\u7ec4\u65ad\u70b9\u3002\u4e5f\u5c31\u662f\u8bf4\u8be5\u8f6f\u4ef6\u5c31\u662f\u4f7f\u7528Linked-read\u6d4b\u5e8f\u65b9\u6cd5\u6765\u68c0\u6d4b\u57fa\u56e0\u7ec4DNA\u5e8f\u5217\u4e2d\u7684\u91cd\u7ec4\u65ad\u70b9\u3002<\/span><span style=\"text-align: center;letter-spacing: 0.578px;\"><\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;white-space: normal;\"><strong><em><span style=\"font-size: 20px;\">\u53c2\u8003\u6587\u732e<\/span><\/em><\/strong><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">DrLink\u662f\u4e00\u4e2a\u751f\u7269\u4fe1\u606f\u5b66\u8f6f\u4ef6\uff0c\u662f\u4e00\u7bc7\u7531Sun\u548cRowan\u7b49\u4eba\u57282019\u5e74\u53d1\u8868\u5728Nature Communications\u4e0a\u7684\u4e00\u7bc7\u8bba\u6587\u6240\u652f\u6301\u7684\u5de5\u5177\u3002\u8be6\u7ec6\u7684\u6e90\u7801\u548c\u7b97\u6cd5\u53ef\u9605\u8bfb\u8be5\u6587\u732e<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;color: rgb(61, 170, 214);\">Linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination<\/span><span style=\"font-size: 14px;\"><\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;white-space: normal;\"><strong><em><span style=\"font-size: 20px;\">\u5b89\u88c5\u6b65\u9aa4<\/span><\/em><\/strong><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em>\u5b89\u88c5\u8981\u6c42<\/em><\/strong><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">Please refer to INSTALL for compiling. The current compilations have been successfully tested on Linux (arch: x_86_64, with g++ version Debian 6.3.0-18+deb9u1 and R version 3.5.1).<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em><span style=\"color: rgb(62, 62, 62);\">\u5b89\u88c5\u7684\u8be6\u7ec6\u6b65\u9aa4<\/span><\/em><\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\"># \u5148\u4ecegithub\u4e0a\u9762\u4e0b\u8f7dDrLink<\/span><\/code><code><span class=\"code-snippet_outer\">git clone https:<span class=\"code-snippet__comment\">\/\/github.com\/schneebergerlab\/DrLink.git<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"># \u5b89\u88c5\u7684\u547d\u4ee4\u884c<\/span><\/code><code><span class=\"code-snippet_outer\"># \u8fdb\u5165\u5230\u4f60\u514b\u9686\u7684DrLink\u8f6f\u4ef6\u7684\u8def\u5f84\u4e2d<\/span><\/code><code><span class=\"code-snippet_outer\">cd \/your_path_to\/DrLink_src<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\"># compile gzstream lib (DrLink works with .gz compressed files with the help of gzstream)<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">cd gzstream<\/span><\/code><code><span class=\"code-snippet_outer\">rm libgzstream.a ..\/gzlib\/libgzstream.a<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">make clean<\/span><\/code><code><span class=\"code-snippet_outer\">make<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">cp libgzstream.a ..\/gzlib<\/span><\/code><code><span class=\"code-snippet_outer\">cd ..<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\"># compile DrLink<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">make<\/span><\/code><code><span class=\"code-snippet_outer\"># \u914d\u7f6e\u73af\u5883\u53d8\u91cf\uff0c\u8fdb\u800c\u53ef\u5b9e\u73b0\u5168\u5c40\u4f7f\u7528<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">export<\/span> PATH=\/media\/desk16\/shb152\/DrLink_src\/:$PATH<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"># test<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">DrLink<\/span><\/code><code><span class=\"code-snippet_outer\"># DrLink\u7684usage<\/span><\/code><code><span class=\"code-snippet_outer\"># which should print the following info<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"># Given linked-read sequencing of recombinants, <span class=\"code-snippet__keyword\">this<\/span> tool identifies meiotic recombinations.<\/span><\/code><code><span class=\"code-snippet_outer\"># (version <span class=\"code-snippet__number\">1.0<\/span> - compiled on MM DD YYYY, HH:MM:SS)<\/span><\/code><code><span class=\"code-snippet_outer\">#<\/span><\/code><code><span class=\"code-snippet_outer\"># Usage: DrLink subprogram [options]<\/span><\/code><code><span class=\"code-snippet_outer\">#<\/span><\/code><code><span class=\"code-snippet_outer\"># Subprograms:<\/span><\/code><code><span class=\"code-snippet_outer\"># preprocess (Usage: please check options with DrLink preprocess)<\/span><\/code><code><span class=\"code-snippet_outer\"># molecule (Usage: please check options with DrLink molecule)<\/span><\/code><code><span class=\"code-snippet_outer\"># recombis (Usage: please check options with DrLink recombis)<\/span><\/code><code><span class=\"code-snippet_outer\"># intersec (Usage: please check options with DrLink intersec)<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;white-space: normal;font-size: 16px;margin-bottom: 0px;letter-spacing: 0.578px;\"><strong><em><span style=\"font-size: 20px;\">\u5b89\u88c5\u65f6\u5e38\u89c1\u7684\u62a5\u9519<\/span><\/em><\/strong><\/p>\n<p style=\"white-space: normal;\"><strong><span style=\"font-size: 14px;\">Git Clone\u9519\u8bef\uff1a<\/span><\/strong><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">GnuTLS recv error (-110): The TLS connection was non-properly terminated.<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u89e3\u51b3\u65b9\u6cd5\uff1a<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">ubuntu\u7cfb\u7edf\u590d\u5236\u4ee3\u7801\u5373\u53ef\uff0ccentos\u7cfb\u7edf\u628a\u6362\u6210yum install\u5373\u53ef<\/span><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">apt-get install gnutls-bin<\/span><\/code><code><span class=\"code-snippet_outer\">git config --global http.sslVerify <span class=\"code-snippet__literal\">false<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">git config --global http.postBuffer <span class=\"code-snippet__number\">1048576000<\/span><\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em><span style=\"color: rgb(62, 62, 62);\">\u7f16\u8bd1\u62a5\u9519<\/span><\/em><\/strong><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u5728\u7f16\u8bd1\u65f6\u62a5\u9519\u4e3b\u8981\u539f\u56e0\u5c31\u662f\u6240\u9700\u8981\u7684\u4f9d\u8d56\u6ca1\u6709\u5b89\u88c5\u5b8c\u6bd5\uff0c\u56e0\u6b64\u9700\u8981\u68c0\u67e5\u81ea\u5df1\u7684\u8bbe\u5907\u662f\u5426\u5b89\u88c5\u597d\u4e86\u8be5\u8f6f\u4ef6\u5b89\u88c5\u548c\u8fd0\u884c\u6240\u9700\u8981\u7684\u4f9d\u8d56<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">The current compilations have been successfully tested on Linux (arch: x_86_64, with g++ version Debian 6.3.0-18+deb9u1 and R version 3.5.1).<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em><span style=\"color: rgb(62, 62, 62);\">g++ or gcc\u62a5\u9519<\/span><\/em><\/strong><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u89e3\u51b3\u65b9\u6848\uff1a\u5b89\u88c5\u65b0\u7248gcc\/g++<\/span><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">##\u521b\u5efa\u865a\u62df\u73af\u5883<\/span><\/code><code><span class=\"code-snippet_outer\">conda create -n g_test -y<\/span><\/code><code><span class=\"code-snippet_outer\">#\u63a8\u8350conda\u4e0b\u8f7d\uff0c\u8981\u662f\u51fa\u95ee\u9898\u4e86\uff0c\u63a8\u51fa\u865a\u62df\u73af\u5883\u7136\u540e\u5220\u9664\u8fd9\u4e2aenv\u5373\u53ef<\/span><\/code><code><span class=\"code-snippet_outer\">conda activate g_test<\/span><\/code><code><span class=\"code-snippet_outer\">conda install -c conda-forge gcc libgcc<\/span><\/code><code><span class=\"code-snippet_outer\">conda install -c conda-forge gxx_linux<span class=\"code-snippet__number\">-64<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"># \u8bf7\u66f4\u6362\u4e3a\u81ea\u5df1\u7684\u8def\u5f84<\/span><\/code><code><span class=\"code-snippet_outer\">cd \/...\/anaconda3\/envs\/...\/bin<\/span><\/code><code><span class=\"code-snippet_outer\"># \u4f7f\u7528\u8f6f\u94fe\u63a5\u4e5f\u662f\uff0c\u8bf7\u66f4\u6362\u4e3a\u81ea\u5df1\u7684\u8def\u5f84\uff0c\u8fd9\u4e00\u6b65\u7684\u76ee\u7684\u662f\u4e3a\u7684\u5f53\u4f7f\u7528\u547d\u4ee4g++\u7684\u65f6\u5019\u53ef\u4ee5\u7528\u6211\u4eec\u521a\u521a\u5b89\u88c5\u597d\u7684g++<\/span><\/code><code><span class=\"code-snippet_outer\">ln -s \/...\/anaconda3\/envs\/...\/bin\/x86_64-conda_cos6-linux-gnu-g++ g++<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;white-space: normal;font-size: 16px;margin-bottom: 0px;letter-spacing: 0.578px;\"><strong><em><span style=\"font-size: 20px;\">\u914d\u7f6e\u73af\u5883\u53d8\u91cf\u76f8\u5173<\/span><\/em><\/strong><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u901a\u5e38\u5728\u5176\u4ed6\u8def\u5f84\u8fd0\u884c\u663e\u793a\u6ca1\u6709\u8fd9\u4e2a\u547d\u4ee4\u5c31\u662f\u6ca1\u6709\u914d\u7f6e\u597d\u73af\u5883\u53d8\u91cf<\/span><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em><span style=\"color: rgb(62, 62, 62);\">\u5728\u5f53\u524d\u7528\u6237\u7684profile\u4e2d<\/span><\/em><\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">\u5728\u5f53\u524d\u7528\u6237\u7684profile\u4e2d\u8bbe\u7f6ePATH<\/span><\/code><code><span class=\"code-snippet_outer\"> vi ~\/.bash_profile<\/span><\/code><code><span class=\"code-snippet_outer\"># \u4fee\u6539PATH\u884c,\u628a\/usr\/local\/apache\/bin\u6dfb\u52a0\u8fdb\u53bb,\u5982\uff1a<\/span><\/code><code><span class=\"code-snippet_outer\">PATH=$PATH:$HOME\/bin:\/media\/desk16\/shb152\/DrLink_src\/<\/span><\/code><code><span class=\"code-snippet_outer\"># \u91cd\u65b0\u52a0\u8f7d\uff0c\u8fdb\u800c\u8ba9\u8fd9\u6b21\u7684\u4fee\u6539\u751f\u6548<\/span><\/code><code><span class=\"code-snippet_outer\">source ~\/.bash_profile<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u6ce8\uff1a\u8fd9\u79cd\u65b9\u6cd5\u53ea\u5bf9\u5f53\u524d\u7528\u6237\u8d77\u4f5c\u7528\u7684,\u5176\u4ed6\u7528\u6237\u8be5\u4fee\u6539\u65e0\u6548\u3002<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em><span style=\"color: rgb(62, 62, 62);\">\u5f53\u524d\u4f1a\u8bdd\u914d\u7f6ePATH<\/span><\/em><\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\"># PATH=$PATH:\/media\/desk16\/shb152\/DrLink_src\/<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u4f7f\u7528\u8fd9\u79cd\u65b9\u6cd5,\u53ea\u5bf9\u5f53\u524d\u4f1a\u8bdd\u6709\u6548\uff0c\u4e5f\u5c31\u662f\u8bf4\u6bcf\u5f53\u767b\u51fa\u6216\u6ce8\u9500\u7cfb\u7edf\u4ee5\u540e\uff0cPATH\u8bbe\u7f6e\u5c31\u4f1a\u5931\u6548\u3002<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em><span style=\"color: rgb(62, 62, 62);\">sudo\u6743\u9650\u53ef\u9009\u62e9\u5728profile\u4e2d\u8bbe\u7f6ePATH\uff0c<\/span><\/em><\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\"># \u5728profile\u4e2d\u8bbe\u7f6ePATH<\/span><\/code><code><span class=\"code-snippet_outer\">vi \/etc\/profile<\/span><\/code><code><span class=\"code-snippet_outer\"># \u627e\u5230<span class=\"code-snippet__keyword\">export<\/span>\u884c\uff0c\u5728\u4e0b\u9762\u65b0\u589e\u52a0\u4e00\u884c\uff0c\u5185\u5bb9\u4e3a\uff1a<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">export<\/span> PATH=$PATH:\/usr\/local\/apache\/bin<\/span><\/code><code><span class=\"code-snippet_outer\"># \u5237\u65b0<\/span><\/code><code><span class=\"code-snippet_outer\">source profile<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u7f16\u8f91\/etc\/profile\u540ePATH\u7684\u4fee\u6539\u4e0d\u4f1a\u7acb\u9a6c\u751f\u6548\uff0c\u6240\u4ee5\u9700\u8981\u7acb\u5373\u751f\u6548\u7684\u8bdd\uff0c\u53ef\u4ee5\u6267\u884c source profile\u547d\u4ee4\u3002<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u8bf7\u6ce8\u610f\uff1a\u5176\u6b21\u5bf9\u4e8eprofile\u6765\u8bf4\u4e00\u5b9a\u8981\u6ce8\u610f\u6574\u4e2a\u7f16\u8f91\u7684\u8fc7\u7a0b\uff0c\u786e\u4fdd\u8f93\u5165\u683c\u5f0f\u6b63\u786e\uff0c\u5426\u5219\u4e00\u65e6\u4f60\u8f93\u5165\u4e00\u4e9b\u683c\u5f0f\u4e0d\u6b63\u786e\u7684\u6587\u672c<span style=\"font-size: 14px;color: rgb(61, 170, 214);\">\uff08\u5982\u628awindows\u7f16\u7801\u7684\u6587\u672c\u590d\u5236\u8fc7\u6765\uff09<\/span>\uff0c\u5c31\u4f1a\u9020\u6210profile\u6587\u4ef6\u65e0\u6cd5\u6b63\u5e38\u89e3\u6790\u7b49\u9519\u8bef\u3002<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u597d\u5566\uff0c\u901a\u8fc7\u5c0f\u679c\u7684\u4ecb\u7ecd\uff0c\u6709\u6ca1\u6709\u770b\u61c2\u4e86\u5462\uff1f<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em><span style=\"color: rgb(62, 62, 62);\">\u6b22\u8fce\u4f7f\u7528\uff1a\u4e91\u751f\u4fe1 – \u5b66\u751f\u7269\u4fe1\u606f\u5b66 (biocloudservice.com)<\/span><\/em><\/strong><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em><span style=\"color: rgb(62, 62, 62);\">\u5982\u679c\u60f3\u7528\u670d\u52a1\u5668\u53ef\u4ee5\u8054\u7cfb\u5fae\u4fe1\uff1a18502195490\uff08\u5feb\u6765\u8054\u7cfb\u6211\u4eec\u4f7f\u7528\u5427\uff01\uff09<\/span><\/em><\/strong><\/p>\n<section style=\"margin-bottom: 0px;letter-spacing: 0.578px;white-space: normal;font-size: 16px;\">\n<section>\n<section powered-by=\"xiumi.us\">\n<p style=\"text-align: center;\"><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section data-tools=\"135\u7f16\u8f91\u5668\" data-id=\"105054\" style=\"margin-bottom: 0px;letter-spacing: 0.578px;white-space: normal;font-size: 16px;\">\n<section style=\"margin: 10px auto;text-align: center;\">\n<section style=\"padding-top: 30px;padding-bottom: 30px;background-color: rgb(242, 246, 255);border-radius: 7px;\">\n<section style=\"display: flex;justify-content: space-evenly;align-items: center;\">\n<section data-width=\"26%\" style=\"width: 150.266px;\">\n<section style=\"padding: 7px;border-radius: 15px;box-shadow: rgba(169, 187, 223, 0.45) 4px 4px 8px, rgb(255, 255, 255) -2.5px -2.5px 5px;\">\n<section data-width=\"100%\" style=\"width: 136.266px;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-cropselx1=\"0\" data-cropselx2=\"136\" data-cropsely1=\"0\" data-cropsely2=\"137\" data-ratio=\"1\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_jEYQoRbKh3HUg3IGgzymibpTnmaM6Q.jpg\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAwIX3hF1ZZeqvXLknM5Oq7CDG9YFpmvU1ge12vc3NvibhViceQjEYQoRbKh3HUg3IGgzymibpTnmaM6Q\/640?wx_fmt=jpeg'\" data-type=\"png\" data-w=\"430\" data-width=\"100%\" style=\"height: 137px;vertical-align: inherit;width: 137px;display: block;border-radius: 7px;\" title=\"\u5c0f\u4e91-\u5fae\u4fe1\u4e8c\u7ef4\u7801.png\"><\/section>\n<\/section>\n<\/section>\n<section data-width=\"62%\" style=\"width: 358.359px;\">\n<section style=\"display: inline-block;\">\n<section style=\"padding: 7px 15px;border-radius: 20px;box-shadow: rgba(169, 187, 223, 0.45) 6px 6px 8px inset, rgb(255, 255, 255) -2.5px -2.5px 5px inset;\">\n<section data-brushtype=\"text\" style=\"font-size: 14px;letter-spacing: 1.5px;color: rgb(111, 133, 172);\">\n<p style=\"text-indent: 0em;line-height: 1.75em;\"><span style=\"letter-spacing: 0.5px;\"><span style=\"letter-spacing: 1.5px;\">\u626b\u7801\u52a0\u5c0f\u679c<\/span><\/span><\/p>\n<p style=\"text-indent: 0em;line-height: 1.75em;\"><span style=\"letter-spacing: 0.5px;\"><span style=\"letter-spacing: 1.5px;\">\u9886\u53d6\u751f\u4fe1\u5927\u793c\u5305<\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin-bottom: 0px;letter-spacing: 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0;\">\n<section>\n<section style=\"display: inline-block;vertical-align: middle;\" powered-by=\"xiumi.us\">\n<section style=\"line-height: 0;\">\n<section style=\"width: 111px;\" powered-by=\"xiumi.us\">\n<section style=\"line-height: 1.75em;text-indent: 0em;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;height: auto;width: 111px;\"><img decoding=\"async\" data-ratio=\"1\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_GBhsibRAgNiaQsH4ichdP9ibEhHMFA-77.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyL6u7wJswOp8vtpzGp6vYngnlT6jiavu08Bvp2iblzGf3IkoBD9NGBhsibRAgNiaQsH4ichdP9ibEhHMFA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"400\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-indent: 0em;line-height: 1.75em;\"><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section data-role=\"list\">\n<section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 8px;text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;\">\n<section style=\"padding-left: 8px;display: inline-block;width: 578px;vertical-align: top;border-left: 3px solid rgb(219, 219, 219);border-bottom-left-radius: 0px;align-self: flex-start;flex: 0 0 auto;\">\n<section powered-by=\"xiumi.us\" style=\"color: rgba(0, 0, 0, 0.5);text-align: justify;\">\n<p><span style=\"font-size: 14px;letter-spacing: 0.578px;\">\u76f8\u4fe1\u5f88\u591a\u533b\u5b66\u76f8\u5173\u7684\u5de5\u4f5c\u8005\u7ecf\u5e38\u82e6\u607c\u4e8eDrLink\u7684\u5b89\u88c5\uff0c\u56e0\u4e3a\u7f51\u4e0a\u7684\u8d44\u6e90\u5b9e\u5728\u662f\u592a\u5c11\u592a\u5c11\u4e86\uff0c\u9664\u4e86\u4e00\u4e2agithub\u4e3b\u9875\u5c31\u662f\u4e00\u7bc7\u6587\u732e\uff0c\u7ecf\u5e38\u6709\u5c0f\u767d\u5b89\u88c5\u62a5\u9519\u65e0\u4ece\u4e0b\u624b\uff0c\u522b\u62c5\u5fc3\uff0c\u4eca\u5929\u4e00\u7bc7\u6587\u7ae0\u6559\u4f60\u5b66\u4f1a\u3002<\/span><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section powered-by=\"xiumi.us\">\n<p style=\"text-align: center;\"><br \/><\/p>\n<section style=\"font-size: 16px;\">\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;white-space: normal;\"><strong><em><span style=\"font-size: 20px;\">DrLink<\/span><\/em><\/strong><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u5b83\u662f\u4e00\u4e2a\u4e0e\u57fa\u56e0\u7ec4\u91cd\u7ec4\u6709\u5173\u7684\u8f6f\u4ef6\uff0c\u5b83\u4f7f\u7528Linked-read\u6d4b\u5e8f\u68c0\u6d4b\u91cd\u7ec4\u65ad\u70b9\u3002\u5b98\u65b9gitHub\u4e2d\u663e\u793a\uff0c\u5b83\u662f\u4e00\u4e2a\u5173\u4e8eDetecting recombination breakpoints using Linked read sequencing\u7684\u8f6f\u4ef6\u3002\u5728\u8fd9\u4e2a\u77ed\u8bed\u4e2d\uff0c\u201cDetecting\u201d\u610f\u5473\u7740\u68c0\u6d4b\u6216\u53d1\u73b0\uff0c\u201crecombination breakpoints\u201d\u6307\u7684\u662f\u57fa\u56e0\u7ec4DNA\u5e8f\u5217\u4e2d\u91cd\u7ec4\u53d1\u751f\u7684\u4f4d\u7f6e\uff0c\u201cLinked-read sequencing\u201d\u662f\u4e00\u79cd\u6d4b\u5e8f\u6280\u672f\uff0c\u5b83\u53ef\u4ee5\u5145\u5206\u5229\u7528\u6761\u5f62\u7801\u6807\u8bb0\u6765\u89e3\u6790\u57fa\u56e0\u7ec4\u533a\u57df\uff0c\u5e76\u66f4\u51c6\u786e\u5730\u786e\u5b9a\u91cd\u7ec4\u65ad\u70b9\u3002\u4e5f\u5c31\u662f\u8bf4\u8be5\u8f6f\u4ef6\u5c31\u662f\u4f7f\u7528Linked-read\u6d4b\u5e8f\u65b9\u6cd5\u6765\u68c0\u6d4b\u57fa\u56e0\u7ec4DNA\u5e8f\u5217\u4e2d\u7684\u91cd\u7ec4\u65ad\u70b9\u3002<\/span><span style=\"text-align: center;letter-spacing: 0.578px;\"><\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;white-space: normal;\"><strong><em><span style=\"font-size: 20px;\">\u53c2\u8003\u6587\u732e<\/span><\/em><\/strong><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">DrLink\u662f\u4e00\u4e2a\u751f\u7269\u4fe1\u606f\u5b66\u8f6f\u4ef6\uff0c\u662f\u4e00\u7bc7\u7531Sun\u548cRowan\u7b49\u4eba\u57282019\u5e74\u53d1\u8868\u5728Nature Communications\u4e0a\u7684\u4e00\u7bc7\u8bba\u6587\u6240\u652f\u6301\u7684\u5de5\u5177\u3002\u8be6\u7ec6\u7684\u6e90\u7801\u548c\u7b97\u6cd5\u53ef\u9605\u8bfb\u8be5\u6587\u732e<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;color: rgb(61, 170, 214);\">Linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination<\/span><span style=\"font-size: 14px;\"><\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;white-space: normal;\"><strong><em><span style=\"font-size: 20px;\">\u5b89\u88c5\u6b65\u9aa4<\/span><\/em><\/strong><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em>\u5b89\u88c5\u8981\u6c42<\/em><\/strong><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">Please refer to INSTALL for compiling. The current compilations have been successfully tested on Linux (arch: x_86_64, with g++ version Debian 6.3.0-18+deb9u1 and R version 3.5.1).<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em><span style=\"color: rgb(62, 62, 62);\">\u5b89\u88c5\u7684\u8be6\u7ec6\u6b65\u9aa4<\/span><\/em><\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\"># \u5148\u4ecegithub\u4e0a\u9762\u4e0b\u8f7dDrLink<\/span><\/code><code><span class=\"code-snippet_outer\">git clone https:<span class=\"code-snippet__comment\">\/\/github.com\/schneebergerlab\/DrLink.git<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"># \u5b89\u88c5\u7684\u547d\u4ee4\u884c<\/span><\/code><code><span class=\"code-snippet_outer\"># \u8fdb\u5165\u5230\u4f60\u514b\u9686\u7684DrLink\u8f6f\u4ef6\u7684\u8def\u5f84\u4e2d<\/span><\/code><code><span class=\"code-snippet_outer\">cd \/your_path_to\/DrLink_src<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\"># compile gzstream lib (DrLink works with .gz compressed files with the help of gzstream)<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">cd gzstream<\/span><\/code><code><span class=\"code-snippet_outer\">rm libgzstream.a ..\/gzlib\/libgzstream.a<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">make clean<\/span><\/code><code><span class=\"code-snippet_outer\">make<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">cp libgzstream.a ..\/gzlib<\/span><\/code><code><span class=\"code-snippet_outer\">cd ..<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\"># compile DrLink<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">make<\/span><\/code><code><span class=\"code-snippet_outer\"># \u914d\u7f6e\u73af\u5883\u53d8\u91cf\uff0c\u8fdb\u800c\u53ef\u5b9e\u73b0\u5168\u5c40\u4f7f\u7528<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">export<\/span> PATH=\/media\/desk16\/shb152\/DrLink_src\/:$PATH<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"># test<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">DrLink<\/span><\/code><code><span class=\"code-snippet_outer\"># DrLink\u7684usage<\/span><\/code><code><span class=\"code-snippet_outer\"># which should print the following info<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"># Given linked-read sequencing of recombinants, <span class=\"code-snippet__keyword\">this<\/span> tool identifies meiotic recombinations.<\/span><\/code><code><span class=\"code-snippet_outer\"># (version <span class=\"code-snippet__number\">1.0<\/span> - compiled on MM DD YYYY, HH:MM:SS)<\/span><\/code><code><span class=\"code-snippet_outer\">#<\/span><\/code><code><span class=\"code-snippet_outer\"># Usage: DrLink subprogram [options]<\/span><\/code><code><span class=\"code-snippet_outer\">#<\/span><\/code><code><span class=\"code-snippet_outer\"># Subprograms:<\/span><\/code><code><span class=\"code-snippet_outer\"># preprocess (Usage: please check options with DrLink preprocess)<\/span><\/code><code><span class=\"code-snippet_outer\"># molecule (Usage: please check options with DrLink molecule)<\/span><\/code><code><span class=\"code-snippet_outer\"># recombis (Usage: please check options with DrLink recombis)<\/span><\/code><code><span class=\"code-snippet_outer\"># intersec (Usage: please check options with DrLink intersec)<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;white-space: normal;font-size: 16px;margin-bottom: 0px;letter-spacing: 0.578px;\"><strong><em><span style=\"font-size: 20px;\">\u5b89\u88c5\u65f6\u5e38\u89c1\u7684\u62a5\u9519<\/span><\/em><\/strong><\/p>\n<p style=\"white-space: normal;\"><strong><span style=\"font-size: 14px;\">Git Clone\u9519\u8bef\uff1a<\/span><\/strong><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">GnuTLS recv error (-110): The TLS connection was non-properly terminated.<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u89e3\u51b3\u65b9\u6cd5\uff1a<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">ubuntu\u7cfb\u7edf\u590d\u5236\u4ee3\u7801\u5373\u53ef\uff0ccentos\u7cfb\u7edf\u628a\u6362\u6210yum install\u5373\u53ef<\/span><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">apt-get install gnutls-bin<\/span><\/code><code><span class=\"code-snippet_outer\">git config --global http.sslVerify <span class=\"code-snippet__literal\">false<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">git config --global http.postBuffer <span class=\"code-snippet__number\">1048576000<\/span><\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em><span style=\"color: rgb(62, 62, 62);\">\u7f16\u8bd1\u62a5\u9519<\/span><\/em><\/strong><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u5728\u7f16\u8bd1\u65f6\u62a5\u9519\u4e3b\u8981\u539f\u56e0\u5c31\u662f\u6240\u9700\u8981\u7684\u4f9d\u8d56\u6ca1\u6709\u5b89\u88c5\u5b8c\u6bd5\uff0c\u56e0\u6b64\u9700\u8981\u68c0\u67e5\u81ea\u5df1\u7684\u8bbe\u5907\u662f\u5426\u5b89\u88c5\u597d\u4e86\u8be5\u8f6f\u4ef6\u5b89\u88c5\u548c\u8fd0\u884c\u6240\u9700\u8981\u7684\u4f9d\u8d56<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">The current compilations have been successfully tested on Linux (arch: x_86_64, with g++ version Debian 6.3.0-18+deb9u1 and R version 3.5.1).<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em><span style=\"color: rgb(62, 62, 62);\">g++ or gcc\u62a5\u9519<\/span><\/em><\/strong><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u89e3\u51b3\u65b9\u6848\uff1a\u5b89\u88c5\u65b0\u7248gcc\/g++<\/span><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">##\u521b\u5efa\u865a\u62df\u73af\u5883<\/span><\/code><code><span class=\"code-snippet_outer\">conda create -n g_test -y<\/span><\/code><code><span class=\"code-snippet_outer\">#\u63a8\u8350conda\u4e0b\u8f7d\uff0c\u8981\u662f\u51fa\u95ee\u9898\u4e86\uff0c\u63a8\u51fa\u865a\u62df\u73af\u5883\u7136\u540e\u5220\u9664\u8fd9\u4e2aenv\u5373\u53ef<\/span><\/code><code><span class=\"code-snippet_outer\">conda activate g_test<\/span><\/code><code><span class=\"code-snippet_outer\">conda install -c conda-forge gcc libgcc<\/span><\/code><code><span class=\"code-snippet_outer\">conda install -c conda-forge gxx_linux<span class=\"code-snippet__number\">-64<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"># \u8bf7\u66f4\u6362\u4e3a\u81ea\u5df1\u7684\u8def\u5f84<\/span><\/code><code><span class=\"code-snippet_outer\">cd \/...\/anaconda3\/envs\/...\/bin<\/span><\/code><code><span class=\"code-snippet_outer\"># \u4f7f\u7528\u8f6f\u94fe\u63a5\u4e5f\u662f\uff0c\u8bf7\u66f4\u6362\u4e3a\u81ea\u5df1\u7684\u8def\u5f84\uff0c\u8fd9\u4e00\u6b65\u7684\u76ee\u7684\u662f\u4e3a\u7684\u5f53\u4f7f\u7528\u547d\u4ee4g++\u7684\u65f6\u5019\u53ef\u4ee5\u7528\u6211\u4eec\u521a\u521a\u5b89\u88c5\u597d\u7684g++<\/span><\/code><code><span class=\"code-snippet_outer\">ln -s \/...\/anaconda3\/envs\/...\/bin\/x86_64-conda_cos6-linux-gnu-g++ g++<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: center;white-space: normal;font-size: 16px;margin-bottom: 0px;letter-spacing: 0.578px;\"><strong><em><span style=\"font-size: 20px;\">\u914d\u7f6e\u73af\u5883\u53d8\u91cf\u76f8\u5173<\/span><\/em><\/strong><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u901a\u5e38\u5728\u5176\u4ed6\u8def\u5f84\u8fd0\u884c\u663e\u793a\u6ca1\u6709\u8fd9\u4e2a\u547d\u4ee4\u5c31\u662f\u6ca1\u6709\u914d\u7f6e\u597d\u73af\u5883\u53d8\u91cf<\/span><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em><span style=\"color: rgb(62, 62, 62);\">\u5728\u5f53\u524d\u7528\u6237\u7684profile\u4e2d<\/span><\/em><\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">\u5728\u5f53\u524d\u7528\u6237\u7684profile\u4e2d\u8bbe\u7f6ePATH<\/span><\/code><code><span class=\"code-snippet_outer\"> vi ~\/.bash_profile<\/span><\/code><code><span class=\"code-snippet_outer\"># \u4fee\u6539PATH\u884c,\u628a\/usr\/local\/apache\/bin\u6dfb\u52a0\u8fdb\u53bb,\u5982\uff1a<\/span><\/code><code><span class=\"code-snippet_outer\">PATH=$PATH:$HOME\/bin:\/media\/desk16\/shb152\/DrLink_src\/<\/span><\/code><code><span class=\"code-snippet_outer\"># \u91cd\u65b0\u52a0\u8f7d\uff0c\u8fdb\u800c\u8ba9\u8fd9\u6b21\u7684\u4fee\u6539\u751f\u6548<\/span><\/code><code><span class=\"code-snippet_outer\">source ~\/.bash_profile<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u6ce8\uff1a\u8fd9\u79cd\u65b9\u6cd5\u53ea\u5bf9\u5f53\u524d\u7528\u6237\u8d77\u4f5c\u7528\u7684,\u5176\u4ed6\u7528\u6237\u8be5\u4fee\u6539\u65e0\u6548\u3002<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em><span style=\"color: rgb(62, 62, 62);\">\u5f53\u524d\u4f1a\u8bdd\u914d\u7f6ePATH<\/span><\/em><\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\"># PATH=$PATH:\/media\/desk16\/shb152\/DrLink_src\/<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u4f7f\u7528\u8fd9\u79cd\u65b9\u6cd5,\u53ea\u5bf9\u5f53\u524d\u4f1a\u8bdd\u6709\u6548\uff0c\u4e5f\u5c31\u662f\u8bf4\u6bcf\u5f53\u767b\u51fa\u6216\u6ce8\u9500\u7cfb\u7edf\u4ee5\u540e\uff0cPATH\u8bbe\u7f6e\u5c31\u4f1a\u5931\u6548\u3002<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em><span style=\"color: rgb(62, 62, 62);\">sudo\u6743\u9650\u53ef\u9009\u62e9\u5728profile\u4e2d\u8bbe\u7f6ePATH\uff0c<\/span><\/em><\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\"># \u5728profile\u4e2d\u8bbe\u7f6ePATH<\/span><\/code><code><span class=\"code-snippet_outer\">vi \/etc\/profile<\/span><\/code><code><span class=\"code-snippet_outer\"># \u627e\u5230<span class=\"code-snippet__keyword\">export<\/span>\u884c\uff0c\u5728\u4e0b\u9762\u65b0\u589e\u52a0\u4e00\u884c\uff0c\u5185\u5bb9\u4e3a\uff1a<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">export<\/span> PATH=$PATH:\/usr\/local\/apache\/bin<\/span><\/code><code><span class=\"code-snippet_outer\"># \u5237\u65b0<\/span><\/code><code><span class=\"code-snippet_outer\">source profile<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u7f16\u8f91\/etc\/profile\u540ePATH\u7684\u4fee\u6539\u4e0d\u4f1a\u7acb\u9a6c\u751f\u6548\uff0c\u6240\u4ee5\u9700\u8981\u7acb\u5373\u751f\u6548\u7684\u8bdd\uff0c\u53ef\u4ee5\u6267\u884c source profile\u547d\u4ee4\u3002<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u8bf7\u6ce8\u610f\uff1a\u5176\u6b21\u5bf9\u4e8eprofile\u6765\u8bf4\u4e00\u5b9a\u8981\u6ce8\u610f\u6574\u4e2a\u7f16\u8f91\u7684\u8fc7\u7a0b\uff0c\u786e\u4fdd\u8f93\u5165\u683c\u5f0f\u6b63\u786e\uff0c\u5426\u5219\u4e00\u65e6\u4f60\u8f93\u5165\u4e00\u4e9b\u683c\u5f0f\u4e0d\u6b63\u786e\u7684\u6587\u672c<span style=\"font-size: 14px;color: rgb(61, 170, 214);\">\uff08\u5982\u628awindows\u7f16\u7801\u7684\u6587\u672c\u590d\u5236\u8fc7\u6765\uff09<\/span>\uff0c\u5c31\u4f1a\u9020\u6210profile\u6587\u4ef6\u65e0\u6cd5\u6b63\u5e38\u89e3\u6790\u7b49\u9519\u8bef\u3002<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\">\u597d\u5566\uff0c\u901a\u8fc7\u5c0f\u679c\u7684\u4ecb\u7ecd\uff0c\u6709\u6ca1\u6709\u770b\u61c2\u4e86\u5462\uff1f<\/span><\/p>\n<p style=\"white-space: normal;\"><span style=\"font-size: 14px;\"><br \/><\/span><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em><span style=\"color: rgb(62, 62, 62);\">\u6b22\u8fce\u4f7f\u7528\uff1a\u4e91\u751f\u4fe1 – \u5b66\u751f\u7269\u4fe1\u606f\u5b66 (biocloudservice.com)<\/span><\/em><\/strong><\/p>\n<p style=\"text-align: left;white-space: normal;\"><strong><em><span style=\"color: rgb(62, 62, 62);\">\u5982\u679c\u60f3\u7528\u670d\u52a1\u5668\u53ef\u4ee5\u8054\u7cfb\u5fae\u4fe1\uff1a18502195490\uff08\u5feb\u6765\u8054\u7cfb\u6211\u4eec\u4f7f\u7528\u5427\uff01\uff09<\/span><\/em><\/strong><\/p>\n<section style=\"margin-bottom: 0px;letter-spacing: 0.578px;white-space: normal;font-size: 16px;\">\n<section>\n<section powered-by=\"xiumi.us\">\n<p style=\"text-align: center;\"><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section data-tools=\"135\u7f16\u8f91\u5668\" data-id=\"105054\" style=\"margin-bottom: 0px;letter-spacing: 0.578px;white-space: normal;font-size: 16px;\">\n<section style=\"margin: 10px auto;text-align: center;\">\n<section style=\"padding-top: 30px;padding-bottom: 30px;background-color: rgb(242, 246, 255);border-radius: 7px;\">\n<section style=\"display: flex;justify-content: space-evenly;align-items: center;\">\n<section data-width=\"26%\" style=\"width: 150.266px;\">\n<section style=\"padding: 7px;border-radius: 15px;box-shadow: rgba(169, 187, 223, 0.45) 4px 4px 8px, rgb(255, 255, 255) -2.5px -2.5px 5px;\">\n<section data-width=\"100%\" style=\"width: 136.266px;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-cropselx1=\"0\" data-cropselx2=\"136\" data-cropsely1=\"0\" data-cropsely2=\"137\" data-ratio=\"1\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_jEYQoRbKh3HUg3IGgzymibpTnmaM6Q.jpg\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAwIX3hF1ZZeqvXLknM5Oq7CDG9YFpmvU1ge12vc3NvibhViceQjEYQoRbKh3HUg3IGgzymibpTnmaM6Q\/640?wx_fmt=jpeg'\" data-type=\"png\" data-w=\"430\" data-width=\"100%\" style=\"height: 137px;vertical-align: inherit;width: 137px;display: block;border-radius: 7px;\" title=\"\u5c0f\u4e91-\u5fae\u4fe1\u4e8c\u7ef4\u7801.png\"><\/section>\n<\/section>\n<\/section>\n<section data-width=\"62%\" style=\"width: 358.359px;\">\n<section style=\"display: inline-block;\">\n<section style=\"padding: 7px 15px;border-radius: 20px;box-shadow: rgba(169, 187, 223, 0.45) 6px 6px 8px inset, rgb(255, 255, 255) -2.5px -2.5px 5px inset;\">\n<section data-brushtype=\"text\" style=\"font-size: 14px;letter-spacing: 1.5px;color: rgb(111, 133, 172);\">\n<p style=\"text-indent: 0em;line-height: 1.75em;\"><span style=\"letter-spacing: 0.5px;\"><span style=\"letter-spacing: 1.5px;\">\u626b\u7801\u52a0\u5c0f\u679c<\/span><\/span><\/p>\n<p style=\"text-indent: 0em;line-height: 1.75em;\"><span style=\"letter-spacing: 0.5px;\"><span style=\"letter-spacing: 1.5px;\">\u9886\u53d6\u751f\u4fe1\u5927\u793c\u5305<\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin-bottom: 0px;letter-spacing: 0.578px;white-space: normal;caret-color: rgba(0, 0, 0, 0);font-size: 16px;\">\n<section>\n<section style=\"margin-top: 0.5em;\">\n<section style=\"padding: 0.5em;border-width: 1px;border-style: solid;box-shadow: rgb(226, 226, 226) 0px 16px 1px -13px;border-color: rgb(0, 150, 136);\">\n<section style=\"text-align: left;\">\n<section style=\"color: rgb(255, 129, 36);text-align: justify;\">\n<section style=\"margin-bottom: 8px;\">\n<p style=\"text-indent: 0em;line-height: 1.75em;\"><span style=\"letter-spacing: 0.5px;\">\u70b9\u51fb<strong><span style=\"color: rgb(0, 150, 136);\">\u201c\u9605\u8bfb\u539f\u6587\u201d<\/span><\/strong>\u7acb\u523b\u62e5\u6709<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin-bottom: 8px;font-size: 32px;color: rgb(0, 150, 136);\">\n<p style=\"text-indent: 0em;line-height: 1.75em;\"><span style=\"letter-spacing: 0.5px;\">\u2193\u2193\u2193 <\/span><span style=\"letter-spacing: 0.5px;text-indent: 0em;\"><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"display: none;\"><mp-style-type data-value=\"3\"><\/mp-style-type><\/p>\n<p><\/content>\n<\/div>\n<p><\/body><br \/>\n<\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>DrLink\u7684\u5b89\u88c5\u7adf\u5982\u6b64\u7b80\u5355\uff1f \u539f\u521b \u5c0f\u679c \u751f\u4fe1\u679c &n […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/55728"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=55728"}],"version-history":[{"count":1,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/55728\/revisions"}],"predecessor-version":[{"id":55731,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/55728\/revisions\/55731"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=55728"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=55728"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=55728"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}