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-apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;color: rgb(62, 62, 62);letter-spacing: 0.034em;\">MSI\u5728\u591a\u79cd\u764c\u75c7\u4e2d\u666e\u904d\u5b58\u5728\uff0c\u5c24\u5176\u662f\u7ed3\u76f4\u80a0\u764c\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 90%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 3px;height: auto;\">\n<section style=\"justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;text-wrap: wrap;\">MSI\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\u5206\u6790\u7684\u5e38\u7528\u65b9\u6cd5\u662f\u901a\u8fc7PCR\u6269\u589e\u80bf\u7624\u7ec4\u7ec7\u548c\u6b63\u5e38\u7ec4\u7ec7\u4e2d\u7684\u4e00\u7ec4\u5fae\u536b\u661f\u6807\u8bb0\u4f4d\u70b9\uff0c\u5e76\u6bd4\u8f83\u5b83\u4eec\u7684DNA\u5e8f\u5217\u957f\u5ea6\u3002\u901a\u5e38\u9009\u62e9\u4e86\u4e00\u7ec4\u5df2\u77e5\u7684\u9ad8\u5ea6\u591a\u6001\u6027\u7684\u5fae\u536b\u661f\u6807\u8bb0\u4f4d\u70b9\uff0c\u8fd9\u4e9b\u4f4d\u70b9\u5728\u6b63\u5e38\u7ec4\u7ec7\u4e2d\u5177\u6709\u7a33\u5b9a\u7684DNA\u5e8f\u5217\u957f\u5ea6\u3002\u5982\u679c\u5728\u80bf\u7624\u7ec4\u7ec7\u4e2d\u53d1\u73b0\u4e86\u4e0e\u6b63\u5e38\u7ec4\u7ec7\u76f8\u6bd4\u663e\u8457\u7684\u5fae\u536b\u661f\u957f\u5ea6\u6539\u53d8\uff08\u5373\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\uff09\uff0c\u5219\u8bf4\u660e\u80bf\u7624\u5177\u6709MSI\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: right;justify-content: flex-end;display: flex;flex-flow: row;margin-top: -40px;margin-bottom: 10px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: flex-start;flex: 0 0 auto;min-width: 5%;height: auto;background-color: rgb(255, 255, 255);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.07757404795486601\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_LReOSDj2gSCiaQSzY4A0EpTXuoaicg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6LLXJBD5qQicsQAXQiaRNwHygCMicticLReOSDj2gSCiaQSzY4A0EpTXuoaicg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"709\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">library(limma)<\/span><\/code><code><span class=\"code-snippet_outer\">library(data.table)<\/span><\/code><code><span class=\"code-snippet_outer\">library(tidyverse)<\/span><\/code><code><span class=\"code-snippet_outer\">library(ggsignif)<\/span><\/code><code><span class=\"code-snippet_outer\">library(RColorBrewer)<\/span><\/code><code><span class=\"code-snippet_outer\">library(<span class=\"code-snippet__built_in\">future<\/span>.apply)<\/span><\/code><code><span class=\"code-snippet_outer\">library(fmsb)<\/span><\/code><code><span class=\"code-snippet_outer\">\u8f7d\u5165R\u5305<\/span><\/code><code><span class=\"code-snippet_outer\">files=dir(<span class=\"code-snippet__string\">\".\/TG_Exp\/\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">#Batch read geneexp files \u6279\u91cf\u8bfb\u53d6\u57fa\u56e0\u8868\u8fbe\u6587\u4ef6<\/span><\/code><code><span class=\"code-snippet_outer\">#\u793a\u4f8b\u57fa\u56e0\u8868\u8fbe\u6587\u4ef6\uff0c<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;text-wrap: wrap;\">\u8fd9\u662f\u4e4b\u524d\u6839\u636etcga\u624b\u52a8\u6279\u91cf\u6574\u7406\u7684\uff0c\u540e\u7eed\u6709\u4eba\u60f3\u4e86\u89e3\uff0c\u53ef\u4ee5\u8054\u7cfb\u5c0f\u5e08\u59b9\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.14007782101167315\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_34LZGkvKXKH4NmiadEmz9NLB5YCpwA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6LVoIXOMgYzaNicSyzxfWibMed98X34LZGkvKXKH4NmiadEmz9NLB5YCpwA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"257\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.7801857585139319\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_A6t6wCRG51kS5swSudpnbK0veZv7dQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6LmlmicdRWUgCmDf7DfuSSbibjatA6t6wCRG51kS5swSudpnbK0veZv7dQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"646\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;text-wrap: wrap;\">##\u4e0b\u9762\u662f\u7f16\u5199\u7684\u4e00\u4e2a\u529f\u80fd\u51fd\u6570\u6765\u6279\u91cf\u8bfb\u53d6\u5904\u7406\u5355\u57fa\u56e0\u8868\u8fbe\u6587\u4ef6\uff0c\u51fd\u6570\u63a5\u53d7\u4e00\u4e2a\u76ee\u5f55\u540d\u4f5c\u4e3a\u8f93\u5165a. \u8bfb\u53d6\u4f4d\u4e8e.\/TG_Exp\/\u76ee\u5f55\u4e2d\u6307\u5b9a\u7684\u76ee\u5f55\u540d\u7684\u57fa\u56e0\u8868\u8fbe\u6587\u4ef6\u3002b. \u8fc7\u6ee4\u6570\u636e\uff0c\u53ea\u4fdd\u7559\u80bf\u7624\u6837\u672c\u3002c. \u4f7f\u7528\u6570\u636e\u7684\u7b2c\u4e00\u5217\u4f5c\u4e3a\u884c\u540d\u3002d. \u53bb\u6389\u8868\u8fbe\u77e9\u9635\u4e2d\u7684\u7b2c\u4e00\u5217\uff0c\u56e0\u4e3a\u7b2c\u4e00\u5217\u901a\u5e38\u662f\u6837\u672c\u540d\uff0c\u4e0d\u662f\u57fa\u56e0\u540d\u3002e. \u89e3\u6790\u76ee\u5f55\u540d\uff0c\u63d0\u53d6\u51fa\u80bf\u7624\u7c7b\u578b\u3002f. \u8bfb\u53d6MSI\uff08\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\uff09\u6570\u636e\uff0cMSI\u6570\u636e\u7684\u6587\u4ef6\u8def\u5f84\u4e3a”.\/MSI.txt”\u3002g. \u8fc7\u6ee4MSI\u548c\u57fa\u56e0\u8868\u8fbe\u6570\u636e\uff0c\u53ea\u4fdd\u7559\u4e24\u8005\u5171\u6709\u7684\u6837\u672c\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">corStatMSI=function(dirname){<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__built_in\">exp<\/span><-read.table(paste0(<span class=\"code-snippet__string\">\".\/TG_Exp\/\"<\/span>,dirname),header=T,sep=<span class=\"code-snippet__string\">'t'<\/span>,check.names=F)<\/span><\/code><code><span class=\"code-snippet_outer\">exp1=subset(<span class=\"code-snippet__built_in\">exp<\/span>,<span class=\"code-snippet__built_in\">exp<\/span>$sample_type==<span class=\"code-snippet__string\">\"tumor\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">rownames(exp1)=exp1[,<span class=\"code-snippet__number\">1<\/span>]<\/span><\/code><code><span class=\"code-snippet_outer\">exp1=exp1[,<span class=\"code-snippet__number\">-1<\/span>]<\/span><\/code><code><span class=\"code-snippet_outer\">#<span class=\"code-snippet__meta\">#names<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">tmp<- strsplit(dirname,split=<span class=\"code-snippet__string\">\".\"<\/span>,fixed=TRUE)<\/span><\/code><code><span class=\"code-snippet_outer\">dirnam<-unlist(lapply(tmp,head,<span class=\"code-snippet__number\">1<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\">##<span class=\"code-snippet__meta\">#read MSI\u8bfb\u53d6MSI\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6570\u636e\uff0c\u4e0b\u9762\u4e3a\u6570\u636e\u793a\u8303\u3002<\/span><\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"1.1214285714285714\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_ic9uBbHqR203FiaBzDlpzJSrh3JHEw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6LCbE3X3NlXPcCbq93krficiaQIOBZic9uBbHqR203FiaBzDlpzJSrh3JHEw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"420\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">MSI=read.table(<span class=\"code-snippet__string\">\".\/MSI.txt\"<\/span>, header=T,sep=<span class=\"code-snippet__string\">\"t\"<\/span>,row.names=<span class=\"code-snippet__number\">1<\/span>,check.names=F)<\/span><\/code><code><span class=\"code-snippet_outer\">rownames(MSI)=substr(rownames(MSI),<span class=\"code-snippet__number\">1<\/span>,nchar(rownames(MSI))<span class=\"code-snippet__number\">-1<\/span>) #\u53bb\u6700\u540e\u4e00\u4e2a\u5b57\u7b26A<\/span><\/code><code><span class=\"code-snippet_outer\">#pass normal<\/span><\/code><code><span class=\"code-snippet_outer\">group=sapply(strsplit(row.names(exp1),<span class=\"code-snippet__string\">\"\\-\"<\/span>),<span class=\"code-snippet__string\">\"[\"<\/span>,<span class=\"code-snippet__number\">4<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">group=sapply(strsplit(group,<span class=\"code-snippet__string\">\"\"<\/span>),<span class=\"code-snippet__string\">\"[\"<\/span>,<span class=\"code-snippet__number\">1<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">group=gsub(<span class=\"code-snippet__string\">\"2\"<\/span>,<span class=\"code-snippet__string\">\"1\"<\/span>,group)<\/span><\/code><code><span class=\"code-snippet_outer\">exp1=exp1[group==<span class=\"code-snippet__number\">0<\/span>,]<\/span><\/code><code><span class=\"code-snippet_outer\">#intersect<\/span><\/code><code><span class=\"code-snippet_outer\">exp1=na.omit(exp1)<\/span><\/code><code><span class=\"code-snippet_outer\">sameSample=intersect(row.names(MSI),row.names(exp1))<\/span><\/code><code><span class=\"code-snippet_outer\">MSI=MSI[sameSample,]<\/span><\/code><code><span class=\"code-snippet_outer\">exp1=exp1[sameSample,]<\/span><\/code><code><span class=\"code-snippet_outer\">#COR TEST<\/span><\/code><code><span class=\"code-snippet_outer\">outTab=data.frame()<\/span><\/code><code><span class=\"code-snippet_outer\">fmsbTab=data.frame()<\/span><\/code><code><span class=\"code-snippet_outer\">tissue=c(<span class=\"code-snippet__string\">\"ACC\"<\/span>, <span class=\"code-snippet__string\">\"BLCA\"<\/span>, <span class=\"code-snippet__string\">\"BRCA\"<\/span>, <span class=\"code-snippet__string\">\"CESC\"<\/span>, <span class=\"code-snippet__string\">\"CHOL\"<\/span>, <span class=\"code-snippet__string\">\"COAD\"<\/span>, <span class=\"code-snippet__string\">\"DLBC\"<\/span>, <span class=\"code-snippet__string\">\"ESCA\"<\/span>, <span class=\"code-snippet__string\">\"GBM\"<\/span>, <span class=\"code-snippet__string\">\"HNSC\"<\/span>, <span class=\"code-snippet__string\">\"KICH\"<\/span>, <span class=\"code-snippet__string\">\"KIRC\"<\/span>, <span class=\"code-snippet__string\">\"KIRP\"<\/span>, <span class=\"code-snippet__string\">\"LGG\"<\/span>, <span class=\"code-snippet__string\">\"LIHC\"<\/span>, <span class=\"code-snippet__string\">\"LUAD\"<\/span>, <span class=\"code-snippet__string\">\"LUSC\"<\/span>, <span class=\"code-snippet__string\">\"MESO\"<\/span>, <span class=\"code-snippet__string\">\"OV\"<\/span>, <span class=\"code-snippet__string\">\"PAAD\"<\/span>, <span class=\"code-snippet__string\">\"PCPG\"<\/span>, <span class=\"code-snippet__string\">\"PRAD\"<\/span>, <span class=\"code-snippet__string\">\"READ\"<\/span>, <span class=\"code-snippet__string\">\"SARC\"<\/span>, <span class=\"code-snippet__string\">\"SKCM\"<\/span>, <span class=\"code-snippet__string\">\"STAD\"<\/span>, <span class=\"code-snippet__string\">\"TGCT\"<\/span>, <span class=\"code-snippet__string\">\"THCA\"<\/span>, <span class=\"code-snippet__string\">\"THYM\"<\/span>, <span class=\"code-snippet__string\">\"UCEC\"<\/span>, <span class=\"code-snippet__string\">\"UCS\"<\/span>, <span class=\"code-snippet__string\">\"UVM\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">#\u5bf9\u80bf\u7624\u7c7b\u578b\u5faa\u73af<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">for<\/span> ( j in <span class=\"code-snippet__number\">1<\/span>:length(tissue) ){<\/span><\/code><code><span class=\"code-snippet_outer\">cancer=tissue[j]<\/span><\/code><code><span class=\"code-snippet_outer\">exp2=exp1[(exp1[,<span class=\"code-snippet__number\">2<\/span>]==cancer),]<\/span><\/code><code><span class=\"code-snippet_outer\">MSI1=MSI[(MSI[,<span class=\"code-snippet__number\">2<\/span>]==cancer),]<\/span><\/code><code><span class=\"code-snippet_outer\">x=as.numeric(MSI1[,<span class=\"code-snippet__number\">1<\/span>])<\/span><\/code><code><span class=\"code-snippet_outer\">y=as.numeric(exp2[,<span class=\"code-snippet__number\">1<\/span>])<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">if<\/span>(length(x)!=length(y)){next}<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">if<\/span>(length(unique(exp2[,<span class=\"code-snippet__number\">1<\/span>]))><span class=\"code-snippet__number\">3<\/span>){<\/span><\/code><code><span class=\"code-snippet_outer\">corT=cor.test(x,y,method=<span class=\"code-snippet__string\">\"spearman\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">cor=corT$estimate<\/span><\/code><code><span class=\"code-snippet_outer\">pValue=corT$p.value<\/span><\/code><code><span class=\"code-snippet_outer\">sig=ifelse(pValue<<span class=\"code-snippet__number\">0.001<\/span>,<span class=\"code-snippet__string\">\"***\"<\/span>,ifelse(pValue<<span class=\"code-snippet__number\">0.01<\/span>,<span class=\"code-snippet__string\">\"**\"<\/span>,ifelse(pValue<<span class=\"code-snippet__number\">0.05<\/span>,<span class=\"code-snippet__string\">\"*\"<\/span>,<span class=\"code-snippet__string\">\" \"<\/span>)))<\/span><\/code><code><span class=\"code-snippet_outer\">outTab=rbind(outTab,cbind(tissue=cancer,cor=cor,pValue=pValue,sig))<\/span><\/code><code><span class=\"code-snippet_outer\">fmsbTab=rbind(fmsbTab,cbind(tissue=cancer,cor=cor))}<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">else<\/span>{next}<\/span><\/code><code><span class=\"code-snippet_outer\">write.table(outTab,paste0(<span class=\"code-snippet__string\">\".\/corStat_MSI\/\"<\/span>,dirnam,<span class=\"code-snippet__string\">\"_\"<\/span>,<span class=\"code-snippet__string\">\"MSI_corStat.txt\"<\/span>),sep=<span class=\"code-snippet__string\">\"t\"<\/span>,row.names=F,quote=F)<\/span><\/code><code><span class=\"code-snippet_outer\">write.table(t(fmsbTab),paste0(<span class=\"code-snippet__string\">\".\/corStat_MSI\/\"<\/span>,dirnam,<span class=\"code-snippet__string\">\"_\"<\/span>,<span class=\"code-snippet__string\">\"MSI_fmsbInput.txt\"<\/span>),sep=<span class=\"code-snippet__string\">\"t\"<\/span>,col.names=F,quote=F)}}<\/span><\/code><code><span class=\"code-snippet_outer\">dd=future_lapply(files,corStatMSI) #\u591a\u6838\u5e76\u884c\u8fd0\u884c<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;margin-bottom: 12px;text-wrap: wrap;\">\u540e\u7eed\u53ef\u4ee5\u7ed9\u5927\u5bb6\u8bb2\u89e3future_lapply\u591a\u6838\u5e76\u884c\u7684\u64cd\u4f5c<\/p>\n<p style=\"text-indent: 2em;text-wrap: wrap;\">\u4e0b\u9762\u4e3a\u6279\u91cf\u751f\u6210\u7684\u7ed3\u679cMSI\u6587\u4ef6txt\uff0c\u4ee5\u5176\u4e2d\u4e00\u4e2a\u5355\u57fa\u56e0\u793a\u8303\u67e5\u770b\u5185\u5bb9\uff0c\u5206\u522b\u5c55\u793a\u4e86\u76f8\u5173\u6027\u548cp\u503c\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.026462395543175487\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_f9ibicSZTXj2UwUodb34IUQzobCibg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6LUACRfMI1bpRiaQ7SRMGShXBS6rMMf9ibicSZTXj2UwUodb34IUQzobCibg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"718\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.8281622911694511\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_lLAPAiccSDCfIgtbzkXKDzHD0pchyg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6Lj7Ket36nspWiakCqfyoQL7qU0nlLAPAiccSDCfIgtbzkXKDzHD0pchyg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"419\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.09814323607427056\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_icnGyNVianoRYdeic12lp7L4K8V1Lg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6LnfZSKN2s3hTdV2A6fYVdKtTuY9JicnGyNVianoRYdeic12lp7L4K8V1Lg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"377\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.6624803767660911\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_hug4Ij7sdKAUjTeNJbRD5xC5iaiccA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6LhujalmUjsqiaicwFmE4m8lprvPW1hug4Ij7sdKAUjTeNJbRD5xC5iaiccA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"637\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.0546875\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_XcdRAYtAmuib9YKczGUGuZvxotnspw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6L3aoy87aSmtOlA3NtLQO59nfajXcdRAYtAmuib9YKczGUGuZvxotnspw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"384\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.2311111111111111\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/10_NSj8OIADBxZ2R3dc4Z8BGiaFh888fw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6L1icD2WVicDP3BGvLueTnwgsus9ibNSj8OIADBxZ2R3dc4Z8BGiaFh888fw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"900\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;margin-bottom: 12px;text-wrap: wrap;\">#\u6279\u91cf\u7ed8\u5236\u96f7\u8fbe\u56fe\uff0c\u8bfb\u53d6\u524d\u9762\u5904\u7406\u597d\u7684\u6570\u636e<\/p>\n<p style=\"text-indent: 2em;text-wrap: wrap;\">\u9996\u5148\uff0c\u4f7f\u7528list.files()\u51fd\u6570\u4ece\u6307\u5b9a\u6587\u4ef6\u5939\u4e2d\u83b7\u53d6\u7b26\u5408\u6761\u4ef6\u7684\u6587\u4ef6\u540d\u5217\u8868\u3002file1\u5b58\u50a8\u4e86\u7b26\u5408”.fmsbInput.txt”\u6a21\u5f0f\u7684\u6587\u4ef6\u540d\u5217\u8868\uff0cfile2\u5b58\u50a8\u4e86\u7b26\u5408”.corStat.txt”\u6a21\u5f0f\u7684\u6587\u4ef6\u540d\u5217\u8868\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">file1 <- <span class=\"code-snippet__built_in\">list<\/span>.files(paste0(<span class=\"code-snippet__string\">\".\/corStat_MSI\"<\/span>), pattern=<span class=\"code-snippet__string\">\"*.fmsbInput.txt\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">file2 <- <span class=\"code-snippet__built_in\">list<\/span>.files(paste0(<span class=\"code-snippet__string\">\".\/corStat_MSI\"<\/span>), pattern=<span class=\"code-snippet__string\">\"*.corStat.txt\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">for<\/span>(i in <span class=\"code-snippet__number\">1<\/span>:length(file1) ){<\/span><\/code><code><span class=\"code-snippet_outer\">data=read.table(paste0(<span class=\"code-snippet__string\">\".\/corStat_MSI\/\"<\/span>,file1[i]),header=T,sep=<span class=\"code-snippet__string\">\"t\"<\/span>,row.names=<span class=\"code-snippet__number\">1<\/span>,check.names=F) <span class=\"code-snippet__meta\">#read<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">a=file1[i]<\/span><\/code><code><span class=\"code-snippet_outer\">a=gsub(<span class=\"code-snippet__string\">\"|_MSI_fmsbInput\\.txt\"<\/span>,<span class=\"code-snippet__string\">\"\"<\/span>,a)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;text-wrap: wrap;\">\u63a5\u4e0b\u6765\uff0c\u901a\u8fc7\u5faa\u73af\u904d\u5386file1\u5217\u8868\u4e2d\u7684\u6bcf\u4e2a\u6587\u4ef6\u540d\uff0c\u8bfb\u53d6\u76f8\u5e94\u7684\u6587\u4ef6\u6570\u636e\uff0c\u5e76\u5bf9\u6570\u636e\u8fdb\u884c\u4e00\u4e9b\u5904\u7406\u64cd\u4f5c\u3002data\u4f7f\u7528read.table()\u51fd\u6570\u4ece\u6587\u4ef6\u4e2d\u8bfb\u53d6\u6570\u636e\uff0c\u5e76\u5c06\u6570\u636e\u5b58\u50a8\u5728\u4e00\u4e2a\u6570\u636e\u6846\u4e2d\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">if<\/span> (length(data)==<span class=\"code-snippet__number\">0<\/span>) {next}<\/span><\/code><code><span class=\"code-snippet_outer\">maxValue=ceiling(max(<span class=\"code-snippet__built_in\">abs<\/span>(data))*<span class=\"code-snippet__number\">10<\/span>)\/<span class=\"code-snippet__number\">10<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">data=rbind(rep(maxValue,ncol(data)),rep(-maxValue,ncol(data)),data)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;text-wrap: wrap;\">\u7136\u540e\uff0c\u901a\u8fc7\u5bf9\u6570\u636e\u8fdb\u884c\u5904\u7406\uff0c\u8ba1\u7b97\u6700\u5927\u503cmaxValue\uff0c\u5e76\u5728\u6570\u636e\u7684\u9876\u90e8\u548c\u5e95\u90e8\u63d2\u5165\u76f8\u5e94\u7684\u6700\u5927\u503c\u6570\u636e\uff0c\u4ee5\u6269\u5c55\u96f7\u8fbe\u56fe\u7684\u8303\u56f4\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#<span class=\"code-snippet__meta\">#color<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">colors=<span class=\"code-snippet__string\">\"blue\"<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#name +sig ***<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">corStat=read.table(paste0(<span class=\"code-snippet__string\">\".\/corStat_MSI\/\"<\/span>,a,<span class=\"code-snippet__string\">\"_MSI_corStat.txt\"<\/span>),header=T,sep=<span class=\"code-snippet__string\">\"t\"<\/span>,row.names=<span class=\"code-snippet__number\">1<\/span>,check.names=F)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">if<\/span> (length(corStat)==<span class=\"code-snippet__number\">0<\/span>) {next}<\/span><\/code><code><span class=\"code-snippet_outer\">colnames(data)=paste0(colnames(data),corStat$sig)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;text-wrap: wrap;\">\u63a5\u4e0b\u6765\uff0c\u6839\u636e\u9700\u6c42\u8bbe\u7f6e\u96f7\u8fbe\u56fe\u7684\u989c\u8272colors\u3002\u7136\u540e\uff0c\u4f7f\u7528read.table()\u51fd\u6570\u8bfb\u53d6\u4e0e\u5f53\u524d\u6587\u4ef6\u5bf9\u5e94\u7684”.corStat.txt”\u6587\u4ef6\u7684\u6570\u636e\uff0c\u5e76\u5b58\u50a8\u5728corStat\u6570\u636e\u6846\u4e2d\u3002\u7136\u540e\uff0c\u6839\u636e\u9700\u6c42\u5bf9\u6570\u636e\u6846\u4e2d\u5217\u7684\u540d\u79f0\u8fdb\u884c\u5904\u7406\uff0c\u5c06\u5176\u4e0ecorStat\u6570\u636e\u6846\u4e2d\u7684sig\u5217\u7684\u503c\u8fdb\u884c\u62fc\u63a5\u3002\u63a5\u4e0b\u6765\uff0c\u6839\u636e\u6587\u4ef6\u540d\u8bbe\u7f6edirname\u548cdirnam\u53d8\u91cf\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">dirname=file1[i]<\/span><\/code><code><span class=\"code-snippet_outer\">tmp<- strsplit(dirname,split=<span class=\"code-snippet__string\">\"_\"<\/span>,fixed=TRUE)<\/span><\/code><code><span class=\"code-snippet_outer\">dirnam<-unlist(lapply(tmp,head,<span class=\"code-snippet__number\">1<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#print<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">pdf(paste0(<span class=\"code-snippet__string\">\".\/RAD\/\"<\/span>,dirnam,<span class=\"code-snippet__string\">\"_MSI_radar.pdf\"<\/span>),height=<span class=\"code-snippet__number\">7<\/span>,width=<span class=\"code-snippet__number\">7<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">radarchart( data, axistype=<span class=\"code-snippet__number\">1<\/span> ,<\/span><\/code><code><span class=\"code-snippet_outer\">pcol=colors, <span class=\"code-snippet__meta\">#color<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">plwd=<span class=\"code-snippet__number\">2<\/span> , <span class=\"code-snippet__meta\">#lwd<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">plty=<span class=\"code-snippet__number\">1<\/span>, <span class=\"code-snippet__meta\">#dotted or solid <span class=\"code-snippet__meta-keyword\">line<\/span><\/span><\/span><\/code><code><span class=\"code-snippet_outer\">cglcol=<span class=\"code-snippet__string\">\"grey\"<\/span>, #Background line color<\/span><\/code><code><span class=\"code-snippet_outer\">cglty=<span class=\"code-snippet__number\">1<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">caxislabels=seq(-maxValue,maxValue,maxValue\/<span class=\"code-snippet__number\">2<\/span>), <span class=\"code-snippet__meta\"># scale<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">cglwd=<span class=\"code-snippet__number\">1.2<\/span>, #Background line thickness<\/span><\/code><code><span class=\"code-snippet_outer\">axislabcol=<span class=\"code-snippet__string\">\"green\"<\/span>, <span class=\"code-snippet__meta\">#color<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">vlcex=<span class=\"code-snippet__number\">0.8<\/span> <span class=\"code-snippet__meta\">#size)dev.off()}<\/span><\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.4092140921409214\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/11_5vk3M71yZ0RZ62ZL3mHWDGhZFsr0wA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6LiaziaaSLoFlNR1n9iaiavopeDjRh5vk3M71yZ0RZ62ZL3mHWDGhZFsr0wA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"738\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.11170212765957446\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/12_gyWWTjsn8BpYibstVjDMKqtRD5OwEA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6Lia0VXSMAzUZy7pL3EqFAAh9r0jgyWWTjsn8BpYibstVjDMKqtRD5OwEA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"376\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;text-wrap: wrap;\">\u6765\u7ed9\u5927\u5bb6\u5c55\u793a\u5c55\u793a\u7ed3\u679c\u56fe\u5427\uff0c\u4f7f\u7528firefox\u547d\u4ee4\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.7087155963302753\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/13_FTYAgM3bziaY46zZJU9dm7Cu6wy7FQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6L3egq5fabEVTnpcxs2ewbapvibaFTYAgM3bziaY46zZJU9dm7Cu6wy7FQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"872\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;margin-bottom: 12px;text-wrap: wrap;\">\u90a3\u4e48\u8fd9\u5c31\u662f\u5355\u57fa\u56e0\u5728\u6cdb\u764c\u4e2d\u7684MSI\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\u7ed3\u679c\u56fe\u3002<\/p>\n<p style=\"text-indent: 2em;margin-bottom: 12px;text-wrap: wrap;\">MSI\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\u7684\u5206\u6790\u5bf9\u4e8e\u764c\u75c7\u7684\u8bca\u65ad\u548c\u9884\u540e\u8bc4\u4f30\u5177\u6709\u91cd\u8981\u610f\u4e49\u3002MSI\u5728\u4e00\u4e9b\u80bf\u7624\u4e2d\u4e0e\u9884\u540e\u8f83\u597d\u3001\u5bf9\u67d0\u4e9b\u5316\u7597\u836f\u7269\u654f\u611f\u7b49\u7279\u70b9\u76f8\u5173\u3002\u56e0\u6b64\uff0c\u5bf9\u4e8e\u7ed3\u76f4\u80a0\u764c\u7b49\u80bf\u7624\uff0c\u8fdb\u884cMSI\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\u5206\u6790\u5df2\u6210\u4e3a\u4e34\u5e8a\u7684\u5e38\u89c4\u68c0\u6d4b\u4e4b\u4e00\u3002<\/p>\n<p style=\"margin-bottom: 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#e7e7eb;}@supports(-webkit-overflow-scrolling:touch){.rich_media_title{font-weight:700}}.rich_media_meta{display:inline-block;vertical-align:middle;padding:0 0 10px 0;font-size:15px;-webkit-tap-highlight-color:rgba(0,0,0,0)}.rich_media_meta.icon_appmsg_tag{margin-right:0px}.rich_media_meta.meta_tag_text{margin-right:0}.rich_media_meta_list em{font-style:normal}.rich_media_meta_text{color:#a5a5a5;}p{margin:0;}.msgBox{margin-top:20px;padding-top:20px;padding-left:50px;overflow:hidden;border-top:2px dashed #09a2ff;}.msg{padding-top:7px;clear:both;}.msgBody{float:right;width:100%;margin-left:55px;padding-bottom:15px;border-bottom:1px dashed #e0e0e0;}.userHeadImg{float:left;margin-left:-50px;}.userHeadImg img{width:40px;height:40px;margin-right:10px;border-radius:3px;}.userName{color:#888888;line-height:24px;font-size:14px;margin:5px 0 5px 0;height:24px;}.replyBody,.autherBody{color:#565656;font-size:15px;}.replyIcon{border-left:4px solid #33ab01;margin-right:5px;}.ad{text-decoration:none;color:#d6d4d4;font-size:12px;}.msgBodyReply{padding-top:5px;}.userName span{float:right;color:#afafaf;font-size:14px;}code{text-align:left;font-size:14px;display:block;white-space:pre;display:-webkit-box;display:-webkit-flex;display:flex;position:relative;}.code-snippet__fix{font-size:14px;margin:10px 0;display:block;color:#333;position:relative;background-color:rgba(0,0,0,0.03);border:1px solid #f0f0f0;border-radius:2px;display:-webkit-box;display:-webkit-flex;display:flex;padding-left:25px;line-height:26px}.code-snippet__fix code{text-align:left;font-size:14px;display:block;white-space:pre;display:-webkit-box;display:-webkit-flex;display:flex;position:relative;font-family:Consolas,\"Liberation 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.code-snippet__title{color:#0e9ce5}.code-snippet__tag,.code-snippet__name,.code-snippet__attribute{color:#0e9ce5;font-weight:normal}.code-snippet__regexp,.code-snippet__link{color:#ca7d37}.code-snippet__symbol,.code-snippet__bullet{color:#d14}.code-snippet__built_in,.code-snippet__builtin-name{color:#ca7d37}.code-snippet__meta{color:#afafaf}.code-snippet__deletion{background:#fdd}.code-snippet__addition{background:#dfd}.code-snippet__emphasis{font-style:italic}.code-snippet__strong{font-weight:bold}.account_avatar{width:40px;height:40px;padding:0;}.account_info{display:-webkit-box;display:-webkit-flex;display:flex;-webkit-box-align:center;-webkit-align-items:center;padding:20px 0;align-items:center}.flex_bd{padding-left:14px;}.account_nickname{display:inline-block;vertical-align:middle;line-height:1.2;color:#576b95;font-size:14px}.account_desc{overflow:hidden;text-overflow:ellipsis;display:-webkit-box;-webkit-box-orient:vertical;-webkit-line-clamp:1;color:rgba(0,0,0,0.3);font-size:14px;line-height:1.2;padding-top:.4em}.msg_source_url{text-align:left;word-break:break-all;margin-top:20px;}.msg_source_url a{padding-right:10px;}.msg_source_url .url_text{color:#a8a8a8;}.video-desc{font-size:14px;margin-top:15px;color:#6c6c6c;}.msg_source_url{text-align:left;}.original_primary_card_tips{color:rgba(0,0,0,0.3);line-height:1.4;font-size:15px;}.weui-flex__item{margin-bottom:20px;padding:20px 16px;margin-top:16px;line-height:1.4;align-items:center;background-color:#f7f7f7;border-radius:8px;position:relative;}.original_primary_desc{color:rgba(0,0,0,0.5);font-size:14px;padding-top:4px;width:auto;overflow:hidden;text-overflow:ellipsis;}.msgBodyReplyList{border-top:1px solid #e1e1e1;margin-top:10px;}.msgBodyReplyListTop{border-top:0;}.reply_like_num{float:right;font-size:14px;color:#c7c7c7;}.msgData{margin-top:20px;color:#626262;}.msgData span{font-size:14px;padding-right:15px;}.msgData .likes{float:right;padding-right:0;}.js_text_content p{font-size:18px;}.rich_media_meta_link{font-size:15px;}blockquote {padding-left: 10px;border-left: 3px solid #dbdbdb;color: rgba(0,0,0,0.5);font-size: 15px;padding-top: 4px;margin: 1em 0;}.video_iframe{width:500px;height:400px;}.blockquote_info{color:#b5b5b5;margin-top:10px;}#copyright_logo{color:#bdbdbd;}.rich_media_meta_list{margin-bottom:10px;}.reprint{background:#efefef;border-radius:5px;padding:8px;color:#1f1f1f;}.reprint a{word-break:break-all;}.topic{color:#8e8e8e;background:#f7f7f7;border-radius:5px;padding:10px 8px;}.topic a{padding-right:5px;}.topic p{margin-bottom:5px;}\n<\/style>\n<link href=\"https:\/\/www.juyifx.cn\/config\/css\/wxArticle.css\" rel=\"stylesheet\"\/>\n<\/head><script>\nvar 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weui-wa-hotarea\" id=\"js_name\">\u751f\u4fe1\u679c <\/a><\/span><em id=\"publish_time\" class=\"rich_media_meta rich_media_meta_text\">2023-09-26 19:00:18<\/em><\/div>\n<p><content><\/p>\n<div class=\"reprint\">\n<p>\u8f6c\u81ea\u516c\u4f17\u53f7\uff1aR\u8bed\u8a00\u5b66\u5f92<br \/><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg5MDk3Mzg4OA==&mid=2247486580&idx=1&sn=233c555aac94fe738e655ff68363400d\" target=\"_blank\" title=\"\u9605\u8bfb\u539f\u6587\" rel=\"noopener\">http:\/\/mp.weixin.qq.com\/s?__biz=Mzg5MDk3Mzg4OA==&mid=2247486580&idx=1&sn=233c555aac94fe738e655ff68363400d<\/a><\/p>\n<\/div>\n<section style=\"font-size: 16px;margin-bottom: 0px;\" data-mpa-powered-by=\"yiban.io\">\n<section style=\"transform: perspective(0px);transform-style: flat;\" powered-by=\"xiumi.us\">\n<section style=\"font-size: 16px;margin-bottom: 0px;\">\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;min-width: 5%;flex: 0 0 auto;height: auto;align-self: flex-start;background-color: rgb(255, 229, 231);padding: 6px 14px 6px 11px;\">\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p><span style=\"text-indent: 2em;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;color: rgb(62, 62, 62);letter-spacing: 0.034em;\">MSI\uff08Microsatellite Instability\uff09\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\u662f\u4e00\u79cd\u9057\u4f20\u53d8\u5f02\u73b0\u8c61\uff0c\u6307\u7684\u662f\u80bf\u7624\u7ec6\u80de\u4e2d\u5fae\u536b\u661fDNA\u91cd\u590d\u5e8f\u5217\u7684\u63d2\u5165\u6216\u7f3a\u5931\uff0c\u5bfc\u81f4\u67d0\u4e9bDNA\u5fae\u536b\u661f\u7684\u957f\u5ea6\u53d1\u751f\u5f02\u5e38\u6539\u53d8\u3002<\/span><span style=\"text-indent: 2em;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;color: rgb(62, 62, 62);letter-spacing: 0.034em;\">MSI\u5728\u591a\u79cd\u764c\u75c7\u4e2d\u666e\u904d\u5b58\u5728\uff0c\u5c24\u5176\u662f\u7ed3\u76f4\u80a0\u764c\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 90%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 3px;height: auto;\">\n<section style=\"justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;text-wrap: wrap;\">MSI\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\u5206\u6790\u7684\u5e38\u7528\u65b9\u6cd5\u662f\u901a\u8fc7PCR\u6269\u589e\u80bf\u7624\u7ec4\u7ec7\u548c\u6b63\u5e38\u7ec4\u7ec7\u4e2d\u7684\u4e00\u7ec4\u5fae\u536b\u661f\u6807\u8bb0\u4f4d\u70b9\uff0c\u5e76\u6bd4\u8f83\u5b83\u4eec\u7684DNA\u5e8f\u5217\u957f\u5ea6\u3002\u901a\u5e38\u9009\u62e9\u4e86\u4e00\u7ec4\u5df2\u77e5\u7684\u9ad8\u5ea6\u591a\u6001\u6027\u7684\u5fae\u536b\u661f\u6807\u8bb0\u4f4d\u70b9\uff0c\u8fd9\u4e9b\u4f4d\u70b9\u5728\u6b63\u5e38\u7ec4\u7ec7\u4e2d\u5177\u6709\u7a33\u5b9a\u7684DNA\u5e8f\u5217\u957f\u5ea6\u3002\u5982\u679c\u5728\u80bf\u7624\u7ec4\u7ec7\u4e2d\u53d1\u73b0\u4e86\u4e0e\u6b63\u5e38\u7ec4\u7ec7\u76f8\u6bd4\u663e\u8457\u7684\u5fae\u536b\u661f\u957f\u5ea6\u6539\u53d8\uff08\u5373\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\uff09\uff0c\u5219\u8bf4\u660e\u80bf\u7624\u5177\u6709MSI\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: right;justify-content: flex-end;display: flex;flex-flow: row;margin-top: -40px;margin-bottom: 10px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: flex-start;flex: 0 0 auto;min-width: 5%;height: auto;background-color: rgb(255, 255, 255);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.07757404795486601\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_LReOSDj2gSCiaQSzY4A0EpTXuoaicg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6LLXJBD5qQicsQAXQiaRNwHygCMicticLReOSDj2gSCiaQSzY4A0EpTXuoaicg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"709\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">library(limma)<\/span><\/code><code><span class=\"code-snippet_outer\">library(data.table)<\/span><\/code><code><span class=\"code-snippet_outer\">library(tidyverse)<\/span><\/code><code><span class=\"code-snippet_outer\">library(ggsignif)<\/span><\/code><code><span class=\"code-snippet_outer\">library(RColorBrewer)<\/span><\/code><code><span class=\"code-snippet_outer\">library(<span class=\"code-snippet__built_in\">future<\/span>.apply)<\/span><\/code><code><span class=\"code-snippet_outer\">library(fmsb)<\/span><\/code><code><span class=\"code-snippet_outer\">\u8f7d\u5165R\u5305<\/span><\/code><code><span class=\"code-snippet_outer\">files=dir(<span class=\"code-snippet__string\">\".\/TG_Exp\/\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">#Batch read geneexp files \u6279\u91cf\u8bfb\u53d6\u57fa\u56e0\u8868\u8fbe\u6587\u4ef6<\/span><\/code><code><span class=\"code-snippet_outer\">#\u793a\u4f8b\u57fa\u56e0\u8868\u8fbe\u6587\u4ef6\uff0c<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;text-wrap: wrap;\">\u8fd9\u662f\u4e4b\u524d\u6839\u636etcga\u624b\u52a8\u6279\u91cf\u6574\u7406\u7684\uff0c\u540e\u7eed\u6709\u4eba\u60f3\u4e86\u89e3\uff0c\u53ef\u4ee5\u8054\u7cfb\u5c0f\u5e08\u59b9\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.14007782101167315\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_34LZGkvKXKH4NmiadEmz9NLB5YCpwA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6LVoIXOMgYzaNicSyzxfWibMed98X34LZGkvKXKH4NmiadEmz9NLB5YCpwA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"257\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.7801857585139319\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_A6t6wCRG51kS5swSudpnbK0veZv7dQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6LmlmicdRWUgCmDf7DfuSSbibjatA6t6wCRG51kS5swSudpnbK0veZv7dQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"646\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;text-wrap: wrap;\">##\u4e0b\u9762\u662f\u7f16\u5199\u7684\u4e00\u4e2a\u529f\u80fd\u51fd\u6570\u6765\u6279\u91cf\u8bfb\u53d6\u5904\u7406\u5355\u57fa\u56e0\u8868\u8fbe\u6587\u4ef6\uff0c\u51fd\u6570\u63a5\u53d7\u4e00\u4e2a\u76ee\u5f55\u540d\u4f5c\u4e3a\u8f93\u5165a. \u8bfb\u53d6\u4f4d\u4e8e.\/TG_Exp\/\u76ee\u5f55\u4e2d\u6307\u5b9a\u7684\u76ee\u5f55\u540d\u7684\u57fa\u56e0\u8868\u8fbe\u6587\u4ef6\u3002b. \u8fc7\u6ee4\u6570\u636e\uff0c\u53ea\u4fdd\u7559\u80bf\u7624\u6837\u672c\u3002c. \u4f7f\u7528\u6570\u636e\u7684\u7b2c\u4e00\u5217\u4f5c\u4e3a\u884c\u540d\u3002d. \u53bb\u6389\u8868\u8fbe\u77e9\u9635\u4e2d\u7684\u7b2c\u4e00\u5217\uff0c\u56e0\u4e3a\u7b2c\u4e00\u5217\u901a\u5e38\u662f\u6837\u672c\u540d\uff0c\u4e0d\u662f\u57fa\u56e0\u540d\u3002e. \u89e3\u6790\u76ee\u5f55\u540d\uff0c\u63d0\u53d6\u51fa\u80bf\u7624\u7c7b\u578b\u3002f. \u8bfb\u53d6MSI\uff08\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\uff09\u6570\u636e\uff0cMSI\u6570\u636e\u7684\u6587\u4ef6\u8def\u5f84\u4e3a”.\/MSI.txt”\u3002g. \u8fc7\u6ee4MSI\u548c\u57fa\u56e0\u8868\u8fbe\u6570\u636e\uff0c\u53ea\u4fdd\u7559\u4e24\u8005\u5171\u6709\u7684\u6837\u672c\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">corStatMSI=function(dirname){<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__built_in\">exp<\/span><-read.table(paste0(<span class=\"code-snippet__string\">\".\/TG_Exp\/\"<\/span>,dirname),header=T,sep=<span class=\"code-snippet__string\">'t'<\/span>,check.names=F)<\/span><\/code><code><span class=\"code-snippet_outer\">exp1=subset(<span class=\"code-snippet__built_in\">exp<\/span>,<span class=\"code-snippet__built_in\">exp<\/span>$sample_type==<span class=\"code-snippet__string\">\"tumor\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">rownames(exp1)=exp1[,<span class=\"code-snippet__number\">1<\/span>]<\/span><\/code><code><span class=\"code-snippet_outer\">exp1=exp1[,<span class=\"code-snippet__number\">-1<\/span>]<\/span><\/code><code><span class=\"code-snippet_outer\">#<span class=\"code-snippet__meta\">#names<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">tmp<- strsplit(dirname,split=<span class=\"code-snippet__string\">\".\"<\/span>,fixed=TRUE)<\/span><\/code><code><span class=\"code-snippet_outer\">dirnam<-unlist(lapply(tmp,head,<span class=\"code-snippet__number\">1<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\">##<span class=\"code-snippet__meta\">#read MSI\u8bfb\u53d6MSI\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6570\u636e\uff0c\u4e0b\u9762\u4e3a\u6570\u636e\u793a\u8303\u3002<\/span><\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"1.1214285714285714\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_ic9uBbHqR203FiaBzDlpzJSrh3JHEw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6LCbE3X3NlXPcCbq93krficiaQIOBZic9uBbHqR203FiaBzDlpzJSrh3JHEw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"420\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">MSI=read.table(<span class=\"code-snippet__string\">\".\/MSI.txt\"<\/span>, header=T,sep=<span class=\"code-snippet__string\">\"t\"<\/span>,row.names=<span class=\"code-snippet__number\">1<\/span>,check.names=F)<\/span><\/code><code><span class=\"code-snippet_outer\">rownames(MSI)=substr(rownames(MSI),<span class=\"code-snippet__number\">1<\/span>,nchar(rownames(MSI))<span class=\"code-snippet__number\">-1<\/span>) #\u53bb\u6700\u540e\u4e00\u4e2a\u5b57\u7b26A<\/span><\/code><code><span class=\"code-snippet_outer\">#pass normal<\/span><\/code><code><span class=\"code-snippet_outer\">group=sapply(strsplit(row.names(exp1),<span class=\"code-snippet__string\">\"\\-\"<\/span>),<span class=\"code-snippet__string\">\"[\"<\/span>,<span class=\"code-snippet__number\">4<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">group=sapply(strsplit(group,<span class=\"code-snippet__string\">\"\"<\/span>),<span class=\"code-snippet__string\">\"[\"<\/span>,<span class=\"code-snippet__number\">1<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">group=gsub(<span class=\"code-snippet__string\">\"2\"<\/span>,<span class=\"code-snippet__string\">\"1\"<\/span>,group)<\/span><\/code><code><span class=\"code-snippet_outer\">exp1=exp1[group==<span class=\"code-snippet__number\">0<\/span>,]<\/span><\/code><code><span class=\"code-snippet_outer\">#intersect<\/span><\/code><code><span class=\"code-snippet_outer\">exp1=na.omit(exp1)<\/span><\/code><code><span class=\"code-snippet_outer\">sameSample=intersect(row.names(MSI),row.names(exp1))<\/span><\/code><code><span class=\"code-snippet_outer\">MSI=MSI[sameSample,]<\/span><\/code><code><span class=\"code-snippet_outer\">exp1=exp1[sameSample,]<\/span><\/code><code><span class=\"code-snippet_outer\">#COR TEST<\/span><\/code><code><span class=\"code-snippet_outer\">outTab=data.frame()<\/span><\/code><code><span class=\"code-snippet_outer\">fmsbTab=data.frame()<\/span><\/code><code><span class=\"code-snippet_outer\">tissue=c(<span class=\"code-snippet__string\">\"ACC\"<\/span>, <span class=\"code-snippet__string\">\"BLCA\"<\/span>, <span class=\"code-snippet__string\">\"BRCA\"<\/span>, <span class=\"code-snippet__string\">\"CESC\"<\/span>, <span class=\"code-snippet__string\">\"CHOL\"<\/span>, <span class=\"code-snippet__string\">\"COAD\"<\/span>, <span class=\"code-snippet__string\">\"DLBC\"<\/span>, <span class=\"code-snippet__string\">\"ESCA\"<\/span>, <span class=\"code-snippet__string\">\"GBM\"<\/span>, <span class=\"code-snippet__string\">\"HNSC\"<\/span>, <span class=\"code-snippet__string\">\"KICH\"<\/span>, <span class=\"code-snippet__string\">\"KIRC\"<\/span>, <span class=\"code-snippet__string\">\"KIRP\"<\/span>, <span class=\"code-snippet__string\">\"LGG\"<\/span>, <span class=\"code-snippet__string\">\"LIHC\"<\/span>, <span class=\"code-snippet__string\">\"LUAD\"<\/span>, <span class=\"code-snippet__string\">\"LUSC\"<\/span>, <span class=\"code-snippet__string\">\"MESO\"<\/span>, <span class=\"code-snippet__string\">\"OV\"<\/span>, <span class=\"code-snippet__string\">\"PAAD\"<\/span>, <span class=\"code-snippet__string\">\"PCPG\"<\/span>, <span class=\"code-snippet__string\">\"PRAD\"<\/span>, <span class=\"code-snippet__string\">\"READ\"<\/span>, <span class=\"code-snippet__string\">\"SARC\"<\/span>, <span class=\"code-snippet__string\">\"SKCM\"<\/span>, <span class=\"code-snippet__string\">\"STAD\"<\/span>, <span class=\"code-snippet__string\">\"TGCT\"<\/span>, <span class=\"code-snippet__string\">\"THCA\"<\/span>, <span class=\"code-snippet__string\">\"THYM\"<\/span>, <span class=\"code-snippet__string\">\"UCEC\"<\/span>, <span class=\"code-snippet__string\">\"UCS\"<\/span>, <span class=\"code-snippet__string\">\"UVM\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">#\u5bf9\u80bf\u7624\u7c7b\u578b\u5faa\u73af<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">for<\/span> ( j in <span class=\"code-snippet__number\">1<\/span>:length(tissue) ){<\/span><\/code><code><span class=\"code-snippet_outer\">cancer=tissue[j]<\/span><\/code><code><span class=\"code-snippet_outer\">exp2=exp1[(exp1[,<span class=\"code-snippet__number\">2<\/span>]==cancer),]<\/span><\/code><code><span class=\"code-snippet_outer\">MSI1=MSI[(MSI[,<span class=\"code-snippet__number\">2<\/span>]==cancer),]<\/span><\/code><code><span class=\"code-snippet_outer\">x=as.numeric(MSI1[,<span class=\"code-snippet__number\">1<\/span>])<\/span><\/code><code><span class=\"code-snippet_outer\">y=as.numeric(exp2[,<span class=\"code-snippet__number\">1<\/span>])<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">if<\/span>(length(x)!=length(y)){next}<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">if<\/span>(length(unique(exp2[,<span class=\"code-snippet__number\">1<\/span>]))><span class=\"code-snippet__number\">3<\/span>){<\/span><\/code><code><span class=\"code-snippet_outer\">corT=cor.test(x,y,method=<span class=\"code-snippet__string\">\"spearman\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">cor=corT$estimate<\/span><\/code><code><span class=\"code-snippet_outer\">pValue=corT$p.value<\/span><\/code><code><span class=\"code-snippet_outer\">sig=ifelse(pValue<<span class=\"code-snippet__number\">0.001<\/span>,<span class=\"code-snippet__string\">\"***\"<\/span>,ifelse(pValue<<span class=\"code-snippet__number\">0.01<\/span>,<span class=\"code-snippet__string\">\"**\"<\/span>,ifelse(pValue<<span class=\"code-snippet__number\">0.05<\/span>,<span class=\"code-snippet__string\">\"*\"<\/span>,<span class=\"code-snippet__string\">\" \"<\/span>)))<\/span><\/code><code><span class=\"code-snippet_outer\">outTab=rbind(outTab,cbind(tissue=cancer,cor=cor,pValue=pValue,sig))<\/span><\/code><code><span class=\"code-snippet_outer\">fmsbTab=rbind(fmsbTab,cbind(tissue=cancer,cor=cor))}<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">else<\/span>{next}<\/span><\/code><code><span class=\"code-snippet_outer\">write.table(outTab,paste0(<span class=\"code-snippet__string\">\".\/corStat_MSI\/\"<\/span>,dirnam,<span class=\"code-snippet__string\">\"_\"<\/span>,<span class=\"code-snippet__string\">\"MSI_corStat.txt\"<\/span>),sep=<span class=\"code-snippet__string\">\"t\"<\/span>,row.names=F,quote=F)<\/span><\/code><code><span class=\"code-snippet_outer\">write.table(t(fmsbTab),paste0(<span class=\"code-snippet__string\">\".\/corStat_MSI\/\"<\/span>,dirnam,<span class=\"code-snippet__string\">\"_\"<\/span>,<span class=\"code-snippet__string\">\"MSI_fmsbInput.txt\"<\/span>),sep=<span class=\"code-snippet__string\">\"t\"<\/span>,col.names=F,quote=F)}}<\/span><\/code><code><span class=\"code-snippet_outer\">dd=future_lapply(files,corStatMSI) #\u591a\u6838\u5e76\u884c\u8fd0\u884c<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;margin-bottom: 12px;text-wrap: wrap;\">\u540e\u7eed\u53ef\u4ee5\u7ed9\u5927\u5bb6\u8bb2\u89e3future_lapply\u591a\u6838\u5e76\u884c\u7684\u64cd\u4f5c<\/p>\n<p style=\"text-indent: 2em;text-wrap: wrap;\">\u4e0b\u9762\u4e3a\u6279\u91cf\u751f\u6210\u7684\u7ed3\u679cMSI\u6587\u4ef6txt\uff0c\u4ee5\u5176\u4e2d\u4e00\u4e2a\u5355\u57fa\u56e0\u793a\u8303\u67e5\u770b\u5185\u5bb9\uff0c\u5206\u522b\u5c55\u793a\u4e86\u76f8\u5173\u6027\u548cp\u503c\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.026462395543175487\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_f9ibicSZTXj2UwUodb34IUQzobCibg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6LUACRfMI1bpRiaQ7SRMGShXBS6rMMf9ibicSZTXj2UwUodb34IUQzobCibg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"718\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.8281622911694511\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_lLAPAiccSDCfIgtbzkXKDzHD0pchyg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6Lj7Ket36nspWiakCqfyoQL7qU0nlLAPAiccSDCfIgtbzkXKDzHD0pchyg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"419\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.09814323607427056\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_icnGyNVianoRYdeic12lp7L4K8V1Lg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6LnfZSKN2s3hTdV2A6fYVdKtTuY9JicnGyNVianoRYdeic12lp7L4K8V1Lg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"377\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.6624803767660911\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_hug4Ij7sdKAUjTeNJbRD5xC5iaiccA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6LhujalmUjsqiaicwFmE4m8lprvPW1hug4Ij7sdKAUjTeNJbRD5xC5iaiccA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"637\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.0546875\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_XcdRAYtAmuib9YKczGUGuZvxotnspw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6L3aoy87aSmtOlA3NtLQO59nfajXcdRAYtAmuib9YKczGUGuZvxotnspw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"384\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.2311111111111111\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/10_NSj8OIADBxZ2R3dc4Z8BGiaFh888fw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6L1icD2WVicDP3BGvLueTnwgsus9ibNSj8OIADBxZ2R3dc4Z8BGiaFh888fw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"900\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;margin-bottom: 12px;text-wrap: wrap;\">#\u6279\u91cf\u7ed8\u5236\u96f7\u8fbe\u56fe\uff0c\u8bfb\u53d6\u524d\u9762\u5904\u7406\u597d\u7684\u6570\u636e<\/p>\n<p style=\"text-indent: 2em;text-wrap: wrap;\">\u9996\u5148\uff0c\u4f7f\u7528list.files()\u51fd\u6570\u4ece\u6307\u5b9a\u6587\u4ef6\u5939\u4e2d\u83b7\u53d6\u7b26\u5408\u6761\u4ef6\u7684\u6587\u4ef6\u540d\u5217\u8868\u3002file1\u5b58\u50a8\u4e86\u7b26\u5408”.fmsbInput.txt”\u6a21\u5f0f\u7684\u6587\u4ef6\u540d\u5217\u8868\uff0cfile2\u5b58\u50a8\u4e86\u7b26\u5408”.corStat.txt”\u6a21\u5f0f\u7684\u6587\u4ef6\u540d\u5217\u8868\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">file1 <- <span class=\"code-snippet__built_in\">list<\/span>.files(paste0(<span class=\"code-snippet__string\">\".\/corStat_MSI\"<\/span>), pattern=<span class=\"code-snippet__string\">\"*.fmsbInput.txt\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">file2 <- <span class=\"code-snippet__built_in\">list<\/span>.files(paste0(<span class=\"code-snippet__string\">\".\/corStat_MSI\"<\/span>), pattern=<span class=\"code-snippet__string\">\"*.corStat.txt\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">for<\/span>(i in <span class=\"code-snippet__number\">1<\/span>:length(file1) ){<\/span><\/code><code><span class=\"code-snippet_outer\">data=read.table(paste0(<span class=\"code-snippet__string\">\".\/corStat_MSI\/\"<\/span>,file1[i]),header=T,sep=<span class=\"code-snippet__string\">\"t\"<\/span>,row.names=<span class=\"code-snippet__number\">1<\/span>,check.names=F) <span class=\"code-snippet__meta\">#read<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">a=file1[i]<\/span><\/code><code><span class=\"code-snippet_outer\">a=gsub(<span class=\"code-snippet__string\">\"|_MSI_fmsbInput\\.txt\"<\/span>,<span class=\"code-snippet__string\">\"\"<\/span>,a)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;text-wrap: wrap;\">\u63a5\u4e0b\u6765\uff0c\u901a\u8fc7\u5faa\u73af\u904d\u5386file1\u5217\u8868\u4e2d\u7684\u6bcf\u4e2a\u6587\u4ef6\u540d\uff0c\u8bfb\u53d6\u76f8\u5e94\u7684\u6587\u4ef6\u6570\u636e\uff0c\u5e76\u5bf9\u6570\u636e\u8fdb\u884c\u4e00\u4e9b\u5904\u7406\u64cd\u4f5c\u3002data\u4f7f\u7528read.table()\u51fd\u6570\u4ece\u6587\u4ef6\u4e2d\u8bfb\u53d6\u6570\u636e\uff0c\u5e76\u5c06\u6570\u636e\u5b58\u50a8\u5728\u4e00\u4e2a\u6570\u636e\u6846\u4e2d\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">if<\/span> (length(data)==<span class=\"code-snippet__number\">0<\/span>) {next}<\/span><\/code><code><span class=\"code-snippet_outer\">maxValue=ceiling(max(<span class=\"code-snippet__built_in\">abs<\/span>(data))*<span class=\"code-snippet__number\">10<\/span>)\/<span class=\"code-snippet__number\">10<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">data=rbind(rep(maxValue,ncol(data)),rep(-maxValue,ncol(data)),data)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;text-wrap: wrap;\">\u7136\u540e\uff0c\u901a\u8fc7\u5bf9\u6570\u636e\u8fdb\u884c\u5904\u7406\uff0c\u8ba1\u7b97\u6700\u5927\u503cmaxValue\uff0c\u5e76\u5728\u6570\u636e\u7684\u9876\u90e8\u548c\u5e95\u90e8\u63d2\u5165\u76f8\u5e94\u7684\u6700\u5927\u503c\u6570\u636e\uff0c\u4ee5\u6269\u5c55\u96f7\u8fbe\u56fe\u7684\u8303\u56f4\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#<span class=\"code-snippet__meta\">#color<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">colors=<span class=\"code-snippet__string\">\"blue\"<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#name +sig ***<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">corStat=read.table(paste0(<span class=\"code-snippet__string\">\".\/corStat_MSI\/\"<\/span>,a,<span class=\"code-snippet__string\">\"_MSI_corStat.txt\"<\/span>),header=T,sep=<span class=\"code-snippet__string\">\"t\"<\/span>,row.names=<span class=\"code-snippet__number\">1<\/span>,check.names=F)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">if<\/span> (length(corStat)==<span class=\"code-snippet__number\">0<\/span>) {next}<\/span><\/code><code><span class=\"code-snippet_outer\">colnames(data)=paste0(colnames(data),corStat$sig)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;text-wrap: wrap;\">\u63a5\u4e0b\u6765\uff0c\u6839\u636e\u9700\u6c42\u8bbe\u7f6e\u96f7\u8fbe\u56fe\u7684\u989c\u8272colors\u3002\u7136\u540e\uff0c\u4f7f\u7528read.table()\u51fd\u6570\u8bfb\u53d6\u4e0e\u5f53\u524d\u6587\u4ef6\u5bf9\u5e94\u7684”.corStat.txt”\u6587\u4ef6\u7684\u6570\u636e\uff0c\u5e76\u5b58\u50a8\u5728corStat\u6570\u636e\u6846\u4e2d\u3002\u7136\u540e\uff0c\u6839\u636e\u9700\u6c42\u5bf9\u6570\u636e\u6846\u4e2d\u5217\u7684\u540d\u79f0\u8fdb\u884c\u5904\u7406\uff0c\u5c06\u5176\u4e0ecorStat\u6570\u636e\u6846\u4e2d\u7684sig\u5217\u7684\u503c\u8fdb\u884c\u62fc\u63a5\u3002\u63a5\u4e0b\u6765\uff0c\u6839\u636e\u6587\u4ef6\u540d\u8bbe\u7f6edirname\u548cdirnam\u53d8\u91cf\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">dirname=file1[i]<\/span><\/code><code><span class=\"code-snippet_outer\">tmp<- strsplit(dirname,split=<span class=\"code-snippet__string\">\"_\"<\/span>,fixed=TRUE)<\/span><\/code><code><span class=\"code-snippet_outer\">dirnam<-unlist(lapply(tmp,head,<span class=\"code-snippet__number\">1<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#print<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">pdf(paste0(<span class=\"code-snippet__string\">\".\/RAD\/\"<\/span>,dirnam,<span class=\"code-snippet__string\">\"_MSI_radar.pdf\"<\/span>),height=<span class=\"code-snippet__number\">7<\/span>,width=<span class=\"code-snippet__number\">7<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">radarchart( data, axistype=<span class=\"code-snippet__number\">1<\/span> ,<\/span><\/code><code><span class=\"code-snippet_outer\">pcol=colors, <span class=\"code-snippet__meta\">#color<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">plwd=<span class=\"code-snippet__number\">2<\/span> , <span class=\"code-snippet__meta\">#lwd<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">plty=<span class=\"code-snippet__number\">1<\/span>, <span class=\"code-snippet__meta\">#dotted or solid <span class=\"code-snippet__meta-keyword\">line<\/span><\/span><\/span><\/code><code><span class=\"code-snippet_outer\">cglcol=<span class=\"code-snippet__string\">\"grey\"<\/span>, #Background line color<\/span><\/code><code><span class=\"code-snippet_outer\">cglty=<span class=\"code-snippet__number\">1<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">caxislabels=seq(-maxValue,maxValue,maxValue\/<span class=\"code-snippet__number\">2<\/span>), <span class=\"code-snippet__meta\"># scale<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">cglwd=<span class=\"code-snippet__number\">1.2<\/span>, #Background line thickness<\/span><\/code><code><span class=\"code-snippet_outer\">axislabcol=<span class=\"code-snippet__string\">\"green\"<\/span>, <span class=\"code-snippet__meta\">#color<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">vlcex=<span class=\"code-snippet__number\">0.8<\/span> <span class=\"code-snippet__meta\">#size)dev.off()}<\/span><\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.4092140921409214\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/11_5vk3M71yZ0RZ62ZL3mHWDGhZFsr0wA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6LiaziaaSLoFlNR1n9iaiavopeDjRh5vk3M71yZ0RZ62ZL3mHWDGhZFsr0wA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"738\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.11170212765957446\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/12_gyWWTjsn8BpYibstVjDMKqtRD5OwEA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6Lia0VXSMAzUZy7pL3EqFAAh9r0jgyWWTjsn8BpYibstVjDMKqtRD5OwEA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"376\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;text-wrap: wrap;\">\u6765\u7ed9\u5927\u5bb6\u5c55\u793a\u5c55\u793a\u7ed3\u679c\u56fe\u5427\uff0c\u4f7f\u7528firefox\u547d\u4ee4\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.7087155963302753\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/13_FTYAgM3bziaY46zZJU9dm7Cu6wy7FQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEWs7IyhY0js20vib6dlJicO6L3egq5fabEVTnpcxs2ewbapvibaFTYAgM3bziaY46zZJU9dm7Cu6wy7FQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"872\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(164, 189, 212);padding: 26px 19px;\">\n<section style=\"text-align: justify;color: rgb(62, 62, 62);\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;margin-bottom: 12px;text-wrap: wrap;\">\u90a3\u4e48\u8fd9\u5c31\u662f\u5355\u57fa\u56e0\u5728\u6cdb\u764c\u4e2d\u7684MSI\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\u7ed3\u679c\u56fe\u3002<\/p>\n<p style=\"text-indent: 2em;margin-bottom: 12px;text-wrap: wrap;\">MSI\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\u7684\u5206\u6790\u5bf9\u4e8e\u764c\u75c7\u7684\u8bca\u65ad\u548c\u9884\u540e\u8bc4\u4f30\u5177\u6709\u91cd\u8981\u610f\u4e49\u3002MSI\u5728\u4e00\u4e9b\u80bf\u7624\u4e2d\u4e0e\u9884\u540e\u8f83\u597d\u3001\u5bf9\u67d0\u4e9b\u5316\u7597\u836f\u7269\u654f\u611f\u7b49\u7279\u70b9\u76f8\u5173\u3002\u56e0\u6b64\uff0c\u5bf9\u4e8e\u7ed3\u76f4\u80a0\u764c\u7b49\u80bf\u7624\uff0c\u8fdb\u884cMSI\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\u5206\u6790\u5df2\u6210\u4e3a\u4e34\u5e8a\u7684\u5e38\u89c4\u68c0\u6d4b\u4e4b\u4e00\u3002<\/p>\n<p style=\"margin-bottom: 12px;text-wrap: wrap;\">\u4e0b\u671f\u5c06\u4e3a\u4f60\u5e26\u6765\u66f4\u591aR\u8bed\u8a00\u7684\u9a9a\u64cd\u4f5c\u6280\u5de7\uff0c\u4ee5\u4e0b\u63a8\u8350\u7684\u662f\u4e00\u4e2a\u591a\u529f\u80fd\u7684\u751f\u4fe1\u5e73\u53f0\u3002<\/p>\n<p style=\"margin-bottom: 12px;text-wrap: wrap;\">\u4e91\u751f\u4fe1\u5e73\u53f0\u94fe\u63a5\uff1ahttp:\/\/www.biocloudservice.com\/home.html<\/p>\n<p style=\"text-wrap: wrap;text-align: center;\">\u4e91\u751f\u4fe1\u5e73\u53f0\u94fe\u63a5\uff1ahttp:\/\/www.biocloudservice.com\/home.html<\/p>\n<p style=\"text-wrap: wrap;text-align: center;\"><br \/><\/p>\n<p style=\"text-wrap: wrap;text-align: center;\"><br \/><\/p>\n<p style=\"text-wrap: wrap;text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"1\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/14_0ywt3meVw6bcicJiaK6yOkawicP48w.jpg?w=640\" 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