{"id":56469,"date":"2024-06-16T17:57:04","date_gmt":"2024-06-16T09:57:04","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=56469"},"modified":"2024-06-16T17:57:04","modified_gmt":"2024-06-16T09:57:04","slug":"%e5%b0%8f%e5%b8%88%e5%a6%b9%e5%b8%a6%e4%bd%a0%e5%a4%84%e7%90%86%e6%89%b9%e9%87%8f%e7%94%9f%e5%ad%98%e5%88%86%e6%9e%90","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=56469","title":{"rendered":"\u5c0f\u5e08\u59b9\u5e26\u4f60\u5904\u7406\u6279\u91cf\u751f\u5b58\u5206\u6790"},"content":{"rendered":"<p><html><br \/>\n<head><br \/>\n<title><\/title><br \/>\n<meta charset=\"utf-8\"><br \/>\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,maximum-scale=1.0,user-scalable=0,viewport-fit=cover\"><\/p>\n<style>\n*{margin:0;padding:0}html{-ms-text-size-adjust:100%;-webkit-text-size-adjust:100%;line-height:1.6}img{z-index:999;position:relative;max-width:100%;margin:10px 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wrap;\">\u751f\u5b58\u5206\u6790\u662f\u4e00\u79cd\u7528\u4e8e\u7814\u7a76\u60a3\u8005\u751f\u5b58\u65f6\u95f4\u548c\u76f8\u5173\u56e0\u7d20\u7684\u7edf\u8ba1\u65b9\u6cd5\u3002\u5728\u80bf\u7624\u7814\u7a76\u4e2d\uff0c\u751f\u5b58\u5206\u6790\u5e38\u7528\u4e8e\u8bc4\u4f30\u60a3\u8005\u7684\u751f\u5b58\u7387\u3001\u9884\u540e\u548c\u6cbb\u7597\u6548\u679c\u3002\u751f\u5b58\u7387\u4f30\u8ba1\uff1a\u901a\u8fc7\u751f\u5b58\u66f2\u7ebf\uff0c\u53ef\u4ee5\u4f30\u8ba1\u60a3\u8005\u5728\u4e0d\u540c\u65f6\u95f4\u70b9\u4e0a\u5b58\u6d3b\u7684\u6982\u7387\u3002\u751f\u5b58\u66f2\u7ebf\u901a\u5e38Kaplan-Meier\u65b9\u6cd5\u7ed8\u5236\uff0c\u6839\u636e\u60a3\u8005\u5728\u89c2\u5bdf\u671f\u95f4\u7684\u4e8b\u4ef6\uff08\u4f8b\u5982\u6b7b\u4ea1\uff09\u548c\u5931\u8bbf\u60c5\u51b5\u6765\u8ba1\u7b97\u3002\u9884\u540e\u8bc4\u4f30\uff1a\u751f\u5b58\u5206\u6790\u53ef\u4ee5\u8bc4\u4f30\u4e0d\u540c\u56e0\u7d20\u5bf9\u60a3\u8005\u9884\u540e\u7684\u5f71\u54cd\u3002\u901a\u8fc7\u5c06\u60a3\u8005\u5206\u4e3a\u4e0d\u540c\u7684\u4e9a\u7ec4\uff0c\u53ef\u4ee5\u6bd4\u8f83\u4e0d\u540c\u4e9a\u7ec4\u4e4b\u95f4\u7684\u751f\u5b58\u5dee\u5f02\u3002<\/p>\n<p style=\"text-indent: 2em;margin-bottom: 12px;text-wrap: wrap;\">\u5e38\u89c1\u7684\u65b9\u6cd5\u5305\u62ecLog-rank\u68c0\u9a8c\u548cCox\u6bd4\u4f8b\u98ce\u9669\u6a21\u578b\uff0c\u7528\u4e8e\u786e\u5b9a\u4e0e\u751f\u5b58\u76f8\u5173\u7684\u9884\u6d4b\u56e0\u7d20\u3002\u9884\u6d4b\u751f\u5b58\uff1a\u57fa\u4e8e\u5df2\u77e5\u7684\u4e34\u5e8a\u548c\u5206\u5b50\u7279\u5f81\uff0c\u751f\u5b58\u5206\u6790\u53ef\u4ee5\u6784\u5efa\u751f\u5b58\u9884\u6d4b\u6a21\u578b\u3002\u8fd9\u4e9b\u6a21\u578b\u53ef\u4ee5\u6839\u636e\u60a3\u8005\u7684\u7279\u5f81\u9884\u6d4b\u5176\u751f\u5b58\u6982\u7387\uff0c\u5e76\u7528\u4e8e\u6307\u5bfc\u6cbb\u7597\u51b3\u7b56\u3002\u5728\u8fdb\u884c\u751f\u5b58\u5206\u6790\u65f6\uff0c\u901a\u5e38\u9700\u8981\u4ee5\u4e0b\u6570\u636e\uff1a\u60a3\u8005\u7684\u751f\u5b58\u65f6\u95f4\uff1a\u8868\u793a\u4ece\u8bca\u65ad\u6216\u6cbb\u7597\u5f00\u59cb\u81f3\u6b7b\u4ea1\u6216\u6700\u540e\u968f\u8bbf\u7684\u65f6\u95f4\u957f\u5ea6\u3002\u4e8b\u4ef6\u6570\u636e\uff1a\u8868\u793a\u60a3\u8005\u662f\u5426\u53d1\u751f\u4e86\u9884\u5b9a\u4e49\u7684\u4e8b\u4ef6\uff0c\u4f8b\u5982\u6b7b\u4ea1\u3002\u5982\u679c\u4e8b\u4ef6\u6ca1\u6709\u53d1\u751f\uff0c\u6216\u8005\u60a3\u8005\u5728\u6700\u540e\u968f\u8bbf\u65f6\u4ecd\u7136\u5b58\u6d3b\uff0c\u5c31\u88ab\u89c6\u4e3a\u5931\u8bbf\u3002\u9884\u6d4b\u56e0\u7d20\uff1a\u5305\u62ec\u4e34\u5e8a\u7279\u5f81\uff08\u5982\u5e74\u9f84\u3001\u6027\u522b\u3001\u75c5\u7406\u5206\u7ea7\u7b49\uff09\u548c\u5206\u5b50\u7279\u5f81\uff08\u5982\u57fa\u56e0\u8868\u8fbe\u3001\u86cb\u767d\u8d28\u6807\u8bb0\u7269\u7b49\uff09\u3002<\/p>\n<p style=\"text-indent: 2em;margin-bottom: 12px;text-wrap: wrap;\">\u751f\u5b58\u5206\u6790\u7684\u6838\u5fc3\u662f\u751f\u5b58\u51fd\u6570\u548c\u751f\u5b58\u66f2\u7ebf\u3002\u751f\u5b58\u51fd\u6570\u63cf\u8ff0\u4e86\u5728\u7ed9\u5b9a\u65f6\u95f4\u70b9\u4e0a\u4e2a\u4f53\u5b58\u6d3b\u4e0b\u6765\u7684\u6982\u7387\uff0c\u751f\u5b58\u66f2\u7ebf\u5219\u662f\u5c06\u751f\u5b58\u51fd\u6570\u53ef\u89c6\u5316\u540e\u5f97\u5230\u7684\u66f2\u7ebf\u56fe\u3002\u901a\u8fc7\u751f\u5b58\u66f2\u7ebf\uff0c\u6211\u4eec\u53ef\u4ee5\u89c2\u5bdf\u4e0d\u540c\u7ec4\u522b\u6216\u6761\u4ef6\u4e0b\u4e2a\u4f53\u7684\u751f\u5b58\u60c5\u51b5\u662f\u5426\u6709\u663e\u8457\u5dee\u5f02\u3002<\/p>\n<p><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"align-items: center;display: flex;margin-right: 0%;margin-bottom: 10px;margin-left: 0%;text-align: left;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;flex: 1 0 1px;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;\" powered-by=\"xiumi.us\">\n<section style=\"border-top: 1px dashed rgb(62, 62, 62);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;flex: 0 1 auto;box-shadow: rgb(0, 0, 0) 0px 0px 0px;line-height: 0;padding-right: 5px;padding-left: 5px;\">\n<section style=\"transform: rotateZ(45deg);\" powered-by=\"xiumi.us\">\n<section style=\"text-align: center;\">\n<section style=\"display: inline-block;width: 10px;height: 10px;vertical-align: top;overflow: hidden;background-color: rgb(255, 222, 23);border-width: 1px;border-style: solid;border-color: rgb(62, 62, 62);box-shadow: rgb(255, 255, 255) 1px 1px 0px inset;line-height: 0;\">\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;flex: 1 0 1px;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;\" powered-by=\"xiumi.us\">\n<section style=\"border-top: 1px dashed rgb(62, 62, 62);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u9996\u5148\uff0c\u52a0\u8f7d\u6240\u9700\u7684\u5305<\/span><\/code><code><span class=\"code-snippet_outer\">library(survival)<\/span><\/code><code><span class=\"code-snippet_outer\">library(survminer)<\/span><\/code><code><span class=\"code-snippet_outer\">library(data.table)<\/span><\/code><code><span class=\"code-snippet_outer\">library(tidyverse)<\/span><\/code><code><span class=\"code-snippet_outer\">#\u4f7f\u7528fread()\u51fd\u6570\u4ece\u6587\u4ef6<span class=\"code-snippet__string\">\"trainRiskOut.txt\"<\/span>\u4e2d\u8bfb\u53d6\u6570\u636e\uff0c\u5e76\u5c06\u5176\u8f6c\u6362\u4e3a\u6570\u636e\u6846\u5bf9\u8c61\u3002\u63a5\u7740\uff0c\u5c06\u7b2c\u4e00\u5217\u4f5c\u4e3a\u884c\u540d\uff0c\u5e76\u79fb\u9664\u7b2c\u4e00\u5217\u3002<\/span><\/code><code><span class=\"code-snippet_outer\">rt=fread(paste0(<span class=\"code-snippet__string\">\".\/trainRiskOut.txt\"<\/span>),header=T,check.names=F)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"1.6090712742980562\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_KiappiaVWVBJYMfz69fz45OFMz92IA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXuWkcJI9W3hTkaTibAoVt42cWiaFkuLKmxaDMM9jiaZgasyPQnAKiappiaVWVBJYMfz69fz45OFMz92IA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"463\" style=\"vertical-align: middle;width: 100%;\"  data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">rt=as.data.frame(rt)<\/span><\/code><code><span class=\"code-snippet_outer\">rownames(rt)=rt[,<span class=\"code-snippet__number\">1<\/span>]<\/span><\/code><code><span class=\"code-snippet_outer\">rt=rt[,<span class=\"code-snippet__number\">-1<\/span>]<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.7739801543550165\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_49DfibQxx0uAM0u6RvzDDKT3WdNiaw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXuWkcJI9W3hTkaTibAoVt42yBbia4BuuPoD6iam4xouKZPdCGxk49DfibQxx0uAM0u6RvzDDKT3WdNiaw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"907\" style=\"vertical-align: middle;width: 100%;\"  data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">rt$futime=rt$futime\/<span class=\"code-snippet__number\">365<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">#\u5c06\u5b58\u6d3b\u65f6\u95f4\uff08futime\uff09\u4ece\u5929\u6570\u8f6c\u6362\u4e3a\u4ee5\u5e74\u4e3a\u5355\u4f4d\uff0c\u4ee5\u4fbf\u8fdb\u884c\u751f\u5b58\u5206\u6790\u3002<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.7493975903614458\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_qQSkBibFich24pFNUM8lT38oD0Wuog.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXuWkcJI9W3hTkaTibAoVt42Y8gLW0Y1zicALwKongx9WQNPQY4qQSkBibFich24pFNUM8lT38oD0Wuog\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"415\" style=\"vertical-align: middle;width: 100%;\"  data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u5bf9\u4e8e\u6570\u636e\u6846\u4e2d\u7684\u7b2c<span class=\"code-snippet__number\">3<\/span>\u5230\u7b2c<span class=\"code-snippet__number\">6<\/span>\u5217\uff08\u57fa\u56e0\u8868\u8fbe\u6570\u636e\uff09\uff0c\u8fdb\u884c\u4ee5\u4e0b\u64cd\u4f5c\uff1a\u5c06\u5b58\u6d3b\u65f6\u95f4\uff08futime\uff09\u8f6c\u6362\u4e3a\u4ee5\u5e74\u4e3a\u5355\u4f4d\u3002\u5bf9\u4e8e\u6bcf\u4e2a\u57fa\u56e0\uff0c\u6839\u636e\u8868\u8fbe\u503c\u7684\u4e2d\u4f4d\u6570\uff0c\u5c06\u60a3\u8005\u5206\u4e3a<span class=\"code-snippet__string\">\"high\"<\/span>\uff08\u9ad8\u98ce\u9669\uff09\u548c<span class=\"code-snippet__string\">\"low\"<\/span>\uff08\u4f4e\u98ce\u9669\uff09\u4e24\u7ec4\u3002\u4f7f\u7528survdiff()\u51fd\u6570\u8ba1\u7b97\u4e24\u7ec4\u4e4b\u95f4\u7684\u751f\u5b58\u5dee\u5f02\uff0c\u5e76\u8ba1\u7b97\u76f8\u5e94\u7684p\u503c\u3002\u4f7f\u7528survfit()\u51fd\u6570\u62df\u5408\u751f\u5b58\u66f2\u7ebf\u3002\u4f7f\u7528ggsurvplot()\u51fd\u6570\u751f\u6210\u751f\u5b58\u66f2\u7ebf\u56fe\uff0c\u5305\u62ec\u98ce\u9669\u7ec4\u522b\u7684\u6807\u6ce8\u3001p\u503c\u7684\u663e\u793a\u548c\u98ce\u8868\u3002\u6700\u540e\uff0c\u5c06\u6bcf\u4e2a\u57fa\u56e0\u7684\u751f\u5b58\u66f2\u7ebf\u56fe\u4fdd\u5b58\u4e3aPDF\u6587\u4ef6\u3002<\/span><\/code><code><span class=\"code-snippet_outer\">#\u5faa\u73af\u904d\u5386\u57fa\u56e0\u5217\u8fdb\u884c\u751f\u5b58\u5206\u6790\u548c\u7ed8\u56fe\uff1a<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">for<\/span> (i in <span class=\"code-snippet__number\">3<\/span>:<span class=\"code-snippet__number\">6<\/span>){<\/span><\/code><code><span class=\"code-snippet_outer\">gene=colnames(rt[i])<\/span><\/code><code><span class=\"code-snippet_outer\">group=ifelse(rt[,i]&gt;median(rt[,i]),<span class=\"code-snippet__string\">\"high\"<\/span>,<span class=\"code-snippet__string\">\"low\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#gene = colnames(rt[i])\uff1a\u83b7\u53d6\u5f53\u524d\u57fa\u56e0\u7684\u540d\u79f0\u3002<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#group = ifelse(rt[, i] &gt; median(rt[, i]), <span class=\"code-snippet__meta-string\">\"high\"<\/span>, <span class=\"code-snippet__meta-string\">\"low\"<\/span>)\uff1a\u6839\u636e\u5f53\u524d\u57fa\u56e0\u7684\u8868\u8fbe\u503c\uff0c\u5c06\u60a3\u8005\u5206\u4e3a<span class=\"code-snippet__meta-string\">\"high\"<\/span>\uff08\u9ad8\u98ce\u9669\uff09\u548c<span class=\"code-snippet__meta-string\">\"low\"<\/span>\uff08\u4f4e\u98ce\u9669\uff09\u4e24\u7ec4\u3002<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">diff=survdiff(Surv(futime, fustat) ~group,data = rt)<\/span><\/code><code><span class=\"code-snippet_outer\">#\u8ba1\u7b97\u4e24\u7ec4\u4e4b\u95f4\u7684\u751f\u5b58\u5dee\u5f02\uff0c\u8fd4\u56de\u76f8\u5173\u7684\u7edf\u8ba1\u7ed3\u679c\u3002<\/span><\/code><code><span class=\"code-snippet_outer\">pValue=<span class=\"code-snippet__number\">1<\/span>-pchisq(diff$chisq,df=<span class=\"code-snippet__number\">1<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">if<\/span>(pValue&lt;<span class=\"code-snippet__number\">0.001<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">{pValue=<span class=\"code-snippet__string\">\"p&lt;0.001\"<\/span>}<span class=\"code-snippet__keyword\">else<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">{pValue=paste0(<span class=\"code-snippet__string\">\"p=\"<\/span>,<span class=\"code-snippet__built_in\">sprintf<\/span>(<span class=\"code-snippet__string\">\"%.03f\"<\/span>,pValue))}<\/span><\/code><code><span class=\"code-snippet_outer\">fit &lt;- survfit(Surv(futime, fustat) ~ group, data = rt)<\/span><\/code><code><span class=\"code-snippet_outer\">#\u62df\u5408\u751f\u5b58\u66f2\u7ebf\u6a21\u578b\u3002<\/span><\/code><code><span class=\"code-snippet_outer\">surPlot=ggsurvplot(fit,<\/span><\/code><code><span class=\"code-snippet_outer\">data=rt,<\/span><\/code><code><span class=\"code-snippet_outer\">title=paste0(<span class=\"code-snippet__string\">\"gene:\"<\/span>,gene=colnames(rt[i])) &nbsp; ,<\/span><\/code><code><span class=\"code-snippet_outer\">conf.<span class=\"code-snippet__keyword\">int<\/span>=F,<\/span><\/code><code><span class=\"code-snippet_outer\">pval=pValue,<\/span><\/code><code><span class=\"code-snippet_outer\">pval.size=<span class=\"code-snippet__number\">6<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">legend.title=<span class=\"code-snippet__string\">\"Risk\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">legend.<span class=\"code-snippet__built_in\">labs<\/span>=c(<span class=\"code-snippet__string\">\"High risk\"<\/span>, <span class=\"code-snippet__string\">\"Low risk\"<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\">xlab=<span class=\"code-snippet__string\">\"Time(years)\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">ylab=<span class=\"code-snippet__string\">\"Overall survival\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">break<\/span>.time.by = <span class=\"code-snippet__number\">3<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">palette=c(<span class=\"code-snippet__string\">\"red\"<\/span>, <span class=\"code-snippet__string\">\"blue\"<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\">risk.table=TRUE,<\/span><\/code><code><span class=\"code-snippet_outer\">risk.table.title=<span class=\"code-snippet__string\">\"\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">risk.table.col = <span class=\"code-snippet__string\">\"strata\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">risk.table.height=<span class=\"code-snippet__number\">.25<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">#\u4f7f\u7528ggsurvplot()\u51fd\u6570\u751f\u6210\u751f\u5b58\u66f2\u7ebf\u56fe\uff0c\u5176\u4e2d\u5305\u62ec\u751f\u5b58\u66f2\u7ebf\u3001p\u503c\u3001\u98ce\u9669\u8868\u7b49\u4fe1\u606f\u3002<\/span><\/code><code><span class=\"code-snippet_outer\">pdf(file=paste0(<span class=\"code-snippet__string\">\"Surv_\"<\/span>,gene,<span class=\"code-snippet__string\">\".pdf\"<\/span>), width = <span class=\"code-snippet__number\">6.5<\/span>, height =<span class=\"code-snippet__number\">5.5<\/span>, onefile = FALSE)<\/span><\/code><code><span class=\"code-snippet_outer\">print(surPlot)<\/span><\/code><code><span class=\"code-snippet_outer\">dev.off() &nbsp;#\u5173\u95edPDF\u8bbe\u5907}}<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.21468926553672316\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_1qFrrfHr7AicnnYv7lqG7cnuYtE45Q.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXuWkcJI9W3hTkaTibAoVt42YqgAMt4zbIKrqIYfWMDOOvhVt1qFrrfHr7AicnnYv7lqG7cnuYtE45Q\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"177\" style=\"vertical-align: middle;width: 100%;\"  data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.5481481481481482\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_IhAlYkqIZMom2M8oE8lv4oK5nR2oeg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXuWkcJI9W3hTkaTibAoVt42CDGel0rVzh7tdibZJ9K58dm3GIhAlYkqIZMom2M8oE8lv4oK5nR2oeg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"135\" style=\"vertical-align: middle;width: 100%;\"  data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.8357142857142857\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_4A8lS4PPVkJdnFd3BPPl5kx69ou8rQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXuWkcJI9W3hTkaTibAoVt42dyG55WtRqsoAgnv0IotD8uFW4A8lS4PPVkJdnFd3BPPl5kx69ou8rQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"840\" style=\"vertical-align: middle;width: 100%;\"  data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.8379052369077307\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_3W8p7xElTXl8YQxkiae6avk26HjyNw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXuWkcJI9W3hTkaTibAoVt42rvblVSuN9t12QLgy2ib2kJwelN3W8p7xElTXl8YQxkiae6avk26HjyNw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"802\" style=\"vertical-align: middle;width: 100%;\"  data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"align-items: center;display: flex;margin-top: 15px;margin-right: 0%;margin-left: 0%;text-align: left;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;flex: 1 1 0%;height: auto;box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"align-items: center;display: flex;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;flex: 1 1 auto;border-width: 0px;box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;\" powered-by=\"xiumi.us\">\n<section style=\"border-top: 1px dashed 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23);border-width: 1px;border-style: solid;border-color: rgb(62, 62, 62);box-shadow: rgb(255, 255, 255) 1px 1px 0px inset;line-height: 0;\">\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;padding: 10px;align-self: flex-start;flex: 0 0 auto;\">\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;margin-bottom: 12px;text-wrap: wrap;\">\u6765\u7ed9\u5927\u5bb6\u5c55\u793a\u5c55\u793a\u7ed3\u679c\u5427\u3002\u90a3\u4e48\u8fd9\u5c31\u662f\u793a\u4f8b\u7ed3\u679c\u56fe\uff0c\u65b9\u4fbf\u540e\u7eed\u5206\u6790\u3002<\/p>\n<p style=\"text-indent: 2em;margin-bottom: 12px;text-wrap: wrap;\">\u5728\u8fdb\u884c\u751f\u5b58\u5206\u6790\u65f6\uff0c\u53ef\u4ee5\u4f7f\u7528\u7edf\u8ba1\u8f6f\u4ef6\uff08\u5982R\u3001SPSS\u3001STATA\u7b49\uff09\u4e2d\u7684\u751f\u5b58\u5206\u6790\u51fd\u6570\u6216\u5305\u6765\u5b9e\u65bd\u76f8\u5173\u65b9\u6cd5\u3002\u8fd9\u4e9b\u8f6f\u4ef6\u63d0\u4f9b\u4e86\u8ba1\u7b97\u751f\u5b58\u66f2\u7ebf\u3001\u6267\u884c\u7edf\u8ba1\u68c0\u9a8c\u548c\u62df\u5408\u751f\u5b58\u6a21\u578b\u7684\u529f\u80fd\u3002<\/p>\n<p style=\"text-indent: 2em;margin-bottom: 12px;text-wrap: wrap;\">\u901a\u8fc7\u751f\u5b58\u5206\u6790\uff0c\u53ef\u4ee5\u83b7\u53d6\u6709\u5173\u80bf\u7624\u60a3\u8005\u751f\u5b58\u60c5\u51b5\u548c\u9884\u540e\u7684\u91cd\u8981\u4fe1\u606f\uff0c\u4e3a\u4e34\u5e8a\u51b3\u7b56\u548c\u6cbb\u7597\u7b56\u7565\u5236\u5b9a\u63d0\u4f9b\u4f9d\u636e\u3002<\/p>\n<p><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"align-items: center;display: flex;margin-right: 0%;margin-bottom: 10px;margin-left: 0%;text-align: left;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;flex: 1 0 1px;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;\" powered-by=\"xiumi.us\">\n<section style=\"border-top: 1px dashed rgb(62, 62, 62);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;flex: 0 1 auto;box-shadow: rgb(0, 0, 0) 0px 0px 0px;line-height: 0;padding-right: 5px;padding-left: 5px;\">\n<section style=\"transform: rotateZ(45deg);\" powered-by=\"xiumi.us\">\n<section style=\"text-align: center;\">\n<section style=\"display: inline-block;width: 10px;height: 10px;vertical-align: top;overflow: hidden;background-color: rgb(255, 222, 23);border-width: 1px;border-style: solid;border-color: rgb(62, 62, 62);box-shadow: rgb(255, 255, 255) 1px 1px 0px inset;line-height: 0;\">\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;flex: 1 0 1px;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;\" powered-by=\"xiumi.us\">\n<section style=\"border-top: 1px dashed rgb(62, 62, 62);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p>\u4e0b\u671f\u5c06\u4e3a\u4f60\u5e26\u6765\u66f4\u591aR\u8bed\u8a00\u7684\u9a9a\u64cd\u4f5c\u6280\u5de7\uff0c\u4ee5\u4e0b\u63a8\u8350\u7684\u662f\u4e00\u4e2a\u591a\u529f\u80fd\u7684\u751f\u4fe1\u5e73\u53f0\u3002<\/p>\n<p>\u4e91\u751f\u4fe1\u5e73\u53f0\u94fe\u63a5\uff1ahttp:\/\/www.biocloudservice.com\/home.html\u3002<\/p>\n<p>\u4e91\u751f\u4fe1\u5e73\u53f0\u94fe\u63a5\uff1ahttp:\/\/www.biocloudservice.com\/home.html\u3002<\/p>\n<\/section>\n<p><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.5555555555555556\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_akXKU5NcO1KwuWc1Rk7ZJ56LC2pYrQ-1.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXjjmsEC5aXz0RE4be2ib1fJPnBD8yX0Z6OF2zocd2ngHpLOakXKU5NcO1KwuWc1Rk7ZJ56LC2pYrQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"900\" style=\"\"  data-recalc-dims=\"1\" \/><\/p>\n<p><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.3488888888888889\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/10_BoDuficWb7YjnP0CXo0mIcibhsXn8w-1.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/oCSOtP61aEUlxqHhbZryhECGXicgBrLn1ZkgkpYia2qsgSgNWPQMp0RiaIAmlBoDuficWb7YjnP0CXo0mIcibhsXn8w\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"900\" style=\"\"  data-recalc-dims=\"1\" \/><\/p>\n<section powered-by=\"xiumi.us\"><br  \/><\/section>\n<\/section>\n<p style=\"display: none;margin-bottom: 24px;\"><mp-style-type data-value=\"3\"><\/mp-style-type><\/p>\n<div class=\"msg_source_url\"><a href=\"https:\/\/v.xiumi.us\/board\/v5\/6rNpH\/475158437\" target=\"_blank\" rel=\"noopener\">\u9605\u8bfb\u539f\u6587<\/a><\/div>\n<p><\/content><\/p>\n<div class=\"msg_source_url\"><a href=\"https:\/\/v.xiumi.us\/board\/v5\/6rNpH\/475158437\" target=\"_blank\" rel=\"noopener\">\u9605\u8bfb\u539f\u6587<\/a><\/div>\n<\/div>\n<p><\/body><br \/>\n<\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5c0f\u5e08\u59b9\u5e26\u4f60\u5904\u7406\u6279\u91cf\u751f\u5b58\u5206\u6790 \u5c0f\u5e08\u59b9&nbsp;&nbsp;\u751f\u4fe1\u679c&nbsp;&nbsp;2023-09-02  [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/56469"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=56469"}],"version-history":[{"count":1,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/56469\/revisions"}],"predecessor-version":[{"id":56480,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/56469\/revisions\/56480"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=56469"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=56469"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=56469"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}