{"id":56509,"date":"2024-06-16T17:59:25","date_gmt":"2024-06-16T09:59:25","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=56509"},"modified":"2024-06-16T17:59:25","modified_gmt":"2024-06-16T09:59:25","slug":"%e4%bd%a0%e7%9c%9f%e7%9a%84%e4%bc%9a%e7%94%bbkm%e6%9b%b2%e7%ba%bf%e5%90%97%ef%bc%9f%e4%b8%80%e6%96%87%e6%8e%8c%e6%8f%a1r%e8%af%ad%e8%a8%80%e7%bb%98%e5%88%b6km%e6%9b%b2%e7%ba%bf%ef%bc%81","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=56509","title":{"rendered":"\u4f60\u771f\u7684\u4f1a\u753bKM\u66f2\u7ebf\u5417\uff1f\u4e00\u6587\u638c\u63e1R\u8bed\u8a00\u7ed8\u5236KM\u66f2\u7ebf\uff01"},"content":{"rendered":"<p><html><br \/>\n<head><br \/>\n<title><\/title><br \/>\n<meta charset=\"utf-8\"><br \/>\n<meta name=\"viewport\" 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\/><\/p>\n<p>\u751f\u5b58\u66f2\u7ebf\u53c8\u79f0Kaplan-Meier\u66f2\u7ebf\uff0c\u6211\u4eec\u4e00\u822c\u7b80\u79f0KM\u66f2\u7ebf\uff0c\u662f\u4e34\u5e8a\u7814\u7a76\u4e2d\u6700\u5e38\u7528\u7684\u56fe\u7247\u4e4b\u4e00\uff0c\u65e8\u5728\u63cf\u8ff0\u5404\u7ec4\u60a3\u8005\u7684\u751f\u5b58\u72b6\u51b5\u3002KM\u66f2\u7ebf\u4e00\u822c\u7528\u4e8e\u663e\u793a\u5728\u7814\u7a76\u671f\u95f4\u751f\u5b58\u6216\u4e8b\u4ef6\u53d1\u751f\u7684\u6982\u7387\u3002\u5b83\u8003\u8651\u4e86\u6837\u672c\u4e2d\u53ef\u80fd\u7684\u622a\u65ad\u548c\u4e0d\u5b8c\u6574\u6570\u636e\uff0c\u8fd9\u4e9b\u6570\u636e\u901a\u5e38\u662f\u7531\u4e8e\u5931\u8bbf\u3001\u968f\u8bbf\u65f6\u95f4\u7ed3\u675f\u6216\u5176\u4ed6\u539f\u56e0\u5bfc\u81f4\u7684\u3002KM\u66f2\u7ebf\u662f\u4e00\u79cd\u975e\u53c2\u6570\u7684\u65b9\u6cd5\uff0c\u5b83\u4e0d\u9700\u8981\u5bf9\u6570\u636e\u8fdb\u884c\u7279\u5b9a\u7684\u5047\u8bbe\u6216\u5206\u5e03\u5047\u8bbe\u3002\u6240\u4ee5\u4e00\u5f20\u6f02\u4eae\u7684\u3001\u4e13\u4e1a\u7684\u751f\u5b58\u66f2\u7ebf\u56fe\u4e0d\u4ec5\u53ef\u4ee5\u4ee4\u7f16\u8f91\u3001\u8bfb\u8005\u548c\u5ba1\u7a3f\u4e13\u5bb6\u773c\u524d\u4e00\u4eae\uff0c\u540c\u65f6\u4e5f\u80fd\u4e3a\u8bba\u6587\u589e\u8272\u4e0d\u5c11\u3002\u6240\u4ee5\u5c0f\u4f19\u4f34\u4eec\u53ef\u4e0d\u8981\u8f7b\u89c6\u4e86\u5b83\u54e6\uff01<\/p>\n<p><br  \/><\/p>\n<p><strong><span style=\"color: rgb(59, 149, 115);\">\u7ed8\u5236KM\u66f2\u7ebf\u7684\u8fc7\u7a0b<\/span><\/strong>\u4e00\u822c\u5206\u4e3a4\u6b65\uff1a<\/p>\n<p>1\u3001\u6536\u96c6\u751f\u5b58\u6570\u636e\uff1a\u9700\u8981\u8bb0\u5f55\u6bcf\u4e2a\u89c2\u5bdf\u5bf9\u8c61\u7684\u8d77\u59cb\u65f6\u95f4\u548c\u7ed3\u675f\u65f6\u95f4\uff0c\u4ee5\u53ca\u662f\u5426\u53d1\u751f\u611f\u5174\u8da3\u7684\u4e8b\u4ef6\uff08\u5982\u6b7b\u4ea1\u3001\u75be\u75c5\u590d\u53d1\u7b49\uff09\u3002<\/p>\n<p>2\u3001\u5bf9\u6570\u636e\u8fdb\u884c\u6392\u5e8f\uff1a\u6839\u636e\u4e8b\u4ef6\u53d1\u751f\u65f6\u95f4\u5bf9\u89c2\u5bdf\u5bf9\u8c61\u8fdb\u884c\u6392\u5e8f\uff0c\u4ee5\u4fbf\u8ba1\u7b97\u751f\u5b58\u6982\u7387\u3002<\/p>\n<p>3\u3001\u8ba1\u7b97\u751f\u5b58\u6982\u7387\uff1a\u6839\u636e\u4e8b\u4ef6\u53d1\u751f\u60c5\u51b5\u548c\u6837\u672c\u6570\u91cf\u8ba1\u7b97\u6bcf\u4e2a\u65f6\u95f4\u70b9\u7684\u751f\u5b58\u6982\u7387\u3002\u5728\u67d0\u4e2a\u65f6\u95f4\u70b9\uff0c\u751f\u5b58\u6982\u7387\u8868\u793a\u5728\u8be5\u65f6\u95f4\u70b9\u4e4b\u524d\u751f\u5b58\u7684\u89c2\u5bdf\u5bf9\u8c61\u6bd4\u4f8b\u3002<\/p>\n<p>4\u3001\u7ed8\u5236KM\u66f2\u7ebf\uff1a\u4f7f\u7528\u7d2f\u79ef\u7684\u751f\u5b58\u6982\u7387\u6765\u7ed8\u5236\u66f2\u7ebf\u3002\u5728\u6bcf\u4e2a\u65f6\u95f4\u70b9\u4e0a\uff0c\u7ed8\u5236\u6a2a\u5750\u6807\u4e3a\u65f6\u95f4\uff0c\u7eb5\u5750\u6807\u4e3a\u751f\u5b58\u6982\u7387\u7684\u70b9\uff0c\u7136\u540e\u7528\u76f4\u7ebf\u5c06\u8fd9\u4e9b\u70b9\u8fde\u63a5\u8d77\u6765\u3002<\/p>\n<p>\u63cf\u8ff0\u4e86\u8fd9\u4e48\u591a\uff0c\u6211\u4eec\u5f00\u59cb\u5b9e\u6218\u5427\uff01\u672c\u6b21\u5206\u6790\u7528\u5230\u7684R\u5305\u4e3b\u8981\u5305\u542b\u4e24\u4e2a\uff0csurvival\u548csurvminer\u3002<\/p>\n<\/section>\n<section style=\"font-size: 12px;line-height: 0;\" powered-by=\"xiumi.us\">\n<p><br  \/><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"r\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u9996\u5148\u5bfc\u5165R\u5305<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">library(survival)<\/span><\/code><code><span class=\"code-snippet_outer\">library(survminer)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u5bfc\u5165\u4e34\u5e8a\u6570\u636e<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">df&lt;-read.csv(<span class=\"code-snippet__string\">\"clinical.csv\"<\/span>,row.names=<span class=\"code-snippet__number\">1<\/span>,header=<span class=\"code-snippet__built_in\">T<\/span>,check.names=<span class=\"code-snippet__built_in\">F<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u83b7\u53d6\u60f3\u8981\u7684\u751f\u5b58\u6570\u636e\uff0c\u5305\u542b\u751f\u5b58\u671f\u3001\u6b7b\u4ea1\u72b6\u6001\u3001\u98ce\u9669\u7c7b\u578b\uff08\u5206\u7ec4\uff09<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">rt=df[,<span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"Overallsurvival\"<\/span>,<span class=\"code-snippet__string\">\"Deadstatus\"<\/span>,<span class=\"code-snippet__string\">\"RiskType\"<\/span>)]<\/span><\/code><code><span class=\"code-snippet_outer\">colnames(rt)[<span class=\"code-snippet__number\">3<\/span>]=<span class=\"code-snippet__string\">\"Type\"<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">head(rt)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"font-size: 12px;line-height: 0;\" powered-by=\"xiumi.us\">\n<p><br  \/><\/p>\n<\/section>\n<section style=\"line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.5185185185185185\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_7u7xDvw9PpTgZtKC2A8SwtK6aic8tg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/mmbiz_png\/YHGRXkSxjSSHSjDO1icgNlBcc30QX2KiakKc2zdKictfibrKk4qod6icewusBF7u7xDvw9PpTgZtKC2A8SwtK6aic8tg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\"  data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"font-size: 12px;line-height: 0;\" powered-by=\"xiumi.us\">\n<p><br  \/><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"r\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u770b\u770b\u5171\u6709\u51e0\u7ec4\u7c7b\u522b<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">groupNum=<span class=\"code-snippet__built_in\">length<\/span>(levels(factor(rt[,<span class=\"code-snippet__string\">\"Type\"<\/span>])))<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u751f\u5b58\u5206\u6790<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">diff=survdiff(Surv(Overallsurvival,Deadstatus)~Type,data=rt)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"font-size: 12px;line-height: 0;\" powered-by=\"xiumi.us\">\n<p><br  \/><\/p>\n<\/section>\n<section style=\"line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.37037037037037035\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_AKyRPqUu4v0bGESm7ibTv8Etc4SWsg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/mmbiz_png\/YHGRXkSxjSSHSjDO1icgNlBcc30QX2Kiak5a6qbP1zl9yrDPytB7iaUuiaJicwAKyRPqUu4v0bGESm7ibTv8Etc4SWsg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\"  data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"font-size: 12px;line-height: 0;\" powered-by=\"xiumi.us\">\n<p><br  \/><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"r\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u5361\u65b9\u68c0\u9a8cP\u503c\u4e3a0.02\uff0c\u8bc1\u660e\u4e24\u7ec4\u751f\u5b58\u5206\u6790\u5b58\u5728\u663e\u8457\u5dee\u5f02<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u8bbe\u7f6e\u4e00\u4e0b\u9608\u503c\u4fdd\u7559\uff0c\u5927\u4e8e0.001\u5c31\u4fdd\u7559\u4e09\u4f4d\u5c0f\u6570\uff0c\u5426\u5219\u5c31\u4e3ap&lt;0.001<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">pValue=diff$p<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">if<\/span>(pValue &lt;<span class=\"code-snippet__number\">0.001<\/span>){<\/span><\/code><code><span class=\"code-snippet_outer\">pValue=<span class=\"code-snippet__string\">\"p&lt;0.001\"<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">}<span class=\"code-snippet__keyword\">else<\/span>{ pValue=paste0(<span class=\"code-snippet__string\">\"p=\"<\/span>,sprintf(<span class=\"code-snippet__string\">\"%.03f\"<\/span>,pValue))<\/span><\/code><code><span class=\"code-snippet_outer\">}<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u62df\u5408\u751f\u5b58\u66f2\u7ebf<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">fit &lt;- survfit(Surv(Overallsurvival, Deadstatus) ~ Type, data = rt)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u5f00\u59cb\u753b\u56fe<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">surPlot=ggsurvplot(fit,<\/span><\/code><code><span class=\"code-snippet_outer\">data=rt,<\/span><\/code><code><span class=\"code-snippet_outer\">conf.int=<span class=\"code-snippet__built_in\">F<\/span>, <span class=\"code-snippet__comment\">#\u7f6e\u4fe1\u533a\u95f4<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">pval=pValue,<\/span><\/code><code><span class=\"code-snippet_outer\">pval.size=<span class=\"code-snippet__number\">4<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">legend.labs=levels(factor(rt[,<span class=\"code-snippet__string\">\"Type\"<\/span>])),<\/span><\/code><code><span class=\"code-snippet_outer\">legend.title= <span class=\"code-snippet__string\">\"Group\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">xlab=<span class=\"code-snippet__string\">\"Time(Day)\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">break.time.by = <span class=\"code-snippet__number\">700<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"font-size: 12px;line-height: 0;\" powered-by=\"xiumi.us\">\n<p><br  \/><\/p>\n<\/section>\n<section style=\"line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.47962962962962963\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_Pn4nTib7INmoqCibEyaDetW0XV4pdQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/mmbiz_png\/YHGRXkSxjSSHSjDO1icgNlBcc30QX2KiakngXyyAJjzQq2INky75m8WOaU0DPn4nTib7INmoqCibEyaDetW0XV4pdQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\"  data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"font-size: 12px;line-height: 0;\" powered-by=\"xiumi.us\">\n<p><br  \/><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"r\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u6309\u7167\u6807\u51c6\u6211\u4eec\u8fd8\u9700\u8981\u6dfb\u52a0\u5206\u7ec4\u6837\u672c\u4fe1\u606f<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u52a0\u4e0arisk.table=T\u53c2\u6570<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">surPlot=ggsurvplot(fit,<\/span><\/code><code><span class=\"code-snippet_outer\">data=rt,<\/span><\/code><code><span class=\"code-snippet_outer\">conf.int=<span class=\"code-snippet__built_in\">F<\/span>, <span class=\"code-snippet__comment\">#\u7f6e\u4fe1\u533a\u95f4<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">pval=pValue,<\/span><\/code><code><span class=\"code-snippet_outer\">pval.size=<span class=\"code-snippet__number\">4<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">legend.labs=levels(rt$Type),<\/span><\/code><code><span class=\"code-snippet_outer\">legend.title=<span class=\"code-snippet__string\">\"Group\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">xlab=<span class=\"code-snippet__string\">\"Time(Day)\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">break.time.by = <span class=\"code-snippet__number\">700<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">risk.table=<span class=\"code-snippet__built_in\">T<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">risk.table.height=<span class=\"code-snippet__number\">.25<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"font-size: 12px;line-height: 0;\" powered-by=\"xiumi.us\">\n<p><br  \/><\/p>\n<\/section>\n<section style=\"line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.7694444444444445\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_sAsicU37pRibmey3ILhC4m4RHNmaAA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/mmbiz_png\/YHGRXkSxjSSHSjDO1icgNlBcc30QX2Kiakib6GR6icqzQ8Efth9elFbhUNcHBVsAsicU37pRibmey3ILhC4m4RHNmaAA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\"  data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"font-size: 12px;line-height: 0;\" powered-by=\"xiumi.us\">\n<p><br  \/><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"r\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u8fd9\u6b21\u5c31\u597d\u591a\u4e86\uff0c\u7136\u540e\u8fd8\u5c11\u4e86HR\u503c\u548c\u7f6e\u4fe1\u533a\u95f4\uff0c\u4e5f\u9700\u8981\u52a0\u4e0a\u53bb<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u901a\u8fc7coxph\u51fd\u6570\u8ba1\u7b97HR\u503c<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">res_cox&lt;-coxph(Surv(Overallsurvival, Deadstatus) ~ Type, data = rt)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"font-size: 12px;line-height: 0;\" powered-by=\"xiumi.us\">\n<p><br  \/><\/p>\n<\/section>\n<section style=\"line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.2675925925925926\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_GfWtBarjYwYm9Puaan7lMvbF1q1DzQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/mmbiz_png\/YHGRXkSxjSSHSjDO1icgNlBcc30QX2KiakzPmcJRDdLyBlzBJ3sYJgicGjXGfWtBarjYwYm9Puaan7lMvbF1q1DzQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\"  data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"font-size: 12px;line-height: 0;\" powered-by=\"xiumi.us\">\n<p><br  \/><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"r\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u7136\u540e\u5c31\u53ef\u4ee5\u6dfb\u52a0\u4e0a\u53bb\u4e86<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">surPlot$plot = surPlot$plot + <\/span><\/code><code><span class=\"code-snippet_outer\">ggplot2::annotate(<span class=\"code-snippet__string\">\"text\"<\/span>,x = <span class=\"code-snippet__number\">280<\/span>, y = <span class=\"code-snippet__number\">0.14<\/span>, <span class=\"code-snippet__comment\">#\u6dfb\u52a0\u5185\u5bb9\u7684\u6240\u5728\u4f4d\u7f6e\uff0c\u53ef\u4ee5\u81ea\u5df1\u8c03\u6574\uff0c\u5927\u6d77\u54e5\u8fd9\u91cc\u662f\u5728\u5de6\u4e0b\u89d2\u7684\u4f4d\u7f6e<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">label = paste(<span class=\"code-snippet__string\">\"HR :\"<\/span>,<span class=\"code-snippet__built_in\">round<\/span>(summary(res_cox)$conf.int[<span class=\"code-snippet__number\">1<\/span>],<span class=\"code-snippet__number\">2<\/span>))) &nbsp;<span class=\"code-snippet__comment\">#\u6dfb\u52a0HR\u503c<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> + ggplot2::annotate(<span class=\"code-snippet__string\">\"text\"<\/span>,x = <span class=\"code-snippet__number\">280<\/span>, y = <span class=\"code-snippet__number\">0.08<\/span>, <\/span><\/code><code><span class=\"code-snippet_outer\">label = paste(<span class=\"code-snippet__string\">\"(\"<\/span>,<span class=\"code-snippet__string\">\"95%CI:\"<\/span>,<span class=\"code-snippet__built_in\">round<\/span>(summary(res_cox)$conf.int[<span class=\"code-snippet__number\">3<\/span>],<span class=\"code-snippet__number\">2<\/span>),<span class=\"code-snippet__string\">\"-\"<\/span>,<span class=\"code-snippet__comment\">#\u6dfb\u52a0\u7f6e\u4fe1\u533a\u95f4<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__built_in\">round<\/span>(summary(res_cox)$conf.int[<span class=\"code-snippet__number\">4<\/span>],<span class=\"code-snippet__number\">2<\/span>),<span class=\"code-snippet__string\">\")\"<\/span>,sep = <span class=\"code-snippet__string\">\"\"<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\">surPlot<\/span><\/code><\/pre>\n<\/section>\n<section style=\"font-size: 12px;line-height: 0;\" powered-by=\"xiumi.us\">\n<p><br  \/><\/p>\n<\/section>\n<section style=\"line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.7574074074074074\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_Wz6jRdicCuJPInDoxhztUNXiaIiaVA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/mmbiz_png\/YHGRXkSxjSSHSjDO1icgNlBcc30QX2Kiakuupm1uAPNL5FPHq8tlDsBrliaz6MWz6jRdicCuJPInDoxhztUNXiaIiaVA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\"  data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"font-size: 12px;line-height: 0;\" powered-by=\"xiumi.us\">\n<p><br  \/><\/p>\n<\/section>\n<section style=\"font-size: 14px;line-height: 1.8;letter-spacing: 2px;padding-right: 10px;padding-left: 10px;\" 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rgb(62, 62, 62);background-color: rgb(231, 215, 173);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;background-color: rgb(245, 241, 224);flex: 100 100 0%;align-self: flex-start;height: auto;border-right: 0px none rgb(62, 62, 62);border-top-right-radius: 12px;overflow: hidden;box-shadow: rgb(231, 215, 173) 0px 6px 0px;\">\n<section style=\"margin: 20px 0% 30px;\" powered-by=\"xiumi.us\">\n<section style=\"padding-right: 23px;padding-left: 23px;text-align: justify;font-size: 14px;line-height: 1.8;letter-spacing: 1px;\">\n<p>\u90a3\u4e48\u5c0f\u4f19\u4f34\u4eec\uff0c\u7ecf\u8fc7\u4eca\u5929\u5927\u6d77\u54e5\u7684\u7ec6\u5fc3\u6307\u5bfc\uff0c\u4f60\u4eec\u6709\u6ca1\u6709\u5b66\u4f1aK\u66f2\u7ebf\u56fe\u7684\u610f\u4e49\u548c\u753b\u56fe\u8fc7\u7a0b\u5462\uff1f\u771f\u6b63\u7684\u5927\u5e08\u6c38\u8fdc\u6000\u7740\u4e00\u9897\u5b66\u5f92\u7684\u5fc3\uff0c\u5e0c\u671b\u5c0f\u4f19\u4f34\u4eec\u52a8\u624b\u8bd5\u4e00\u8bd5\uff0c\u8bf4\u4e0d\u5b9a\u4f1a\u6709\u610f\u5916\u7684\u6536\u83b7\u54e6\uff01\uff08<strong><span style=\"color: rgb(59, 149, 115);\">\u6700\u540e\u63a8\u8350\u4e00\u4e0b\u5927\u6d77\u54e5\u65b0\u5f00\u53d1\u7684\u96f6\u4ee3\u7801\u4e91\u751f\u4fe1\u5206\u6790\u5de5\u5177\u5e73\u53f0\uff0c\u5305\u542b\u8d85\u591a\u96f6\u4ee3\u7801\u5c0f\u5de5\u5177\uff0c\u4e0a\u4f20\u6570\u636e\u4e00\u4ef6\u51fa\u56fe\uff0c\u611f\u5174\u8da3\u7684\u5c0f\u4f19\u4f34\u6b22\u8fce\u6765\u53c2\u89c2\u54df\uff0c\u7f51\u5740\uff1ahttp:\/\/www.biocloudservice.com\/home.html<\/span><\/strong>\uff09<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br  \/><\/p>\n<section style=\"border-bottom: 2px solid rgb(0, 150, 136);text-align: left;font-size: 14px;\" powered-by=\"xiumi.us\">\n<p>\u70b9\u51fb\u201c\u9605\u8bfb\u539f\u6587\u201d\u8fdb\u5165\u7f51\u5740<\/p>\n<\/section>\n<section style=\"margin-left: 8%;margin-right: 8%;line-height: 1.1em;\" powered-by=\"xiumi.us\">\n<section style=\"width: 0px;display: inline-block;vertical-align: top;border-top: 1em solid rgb(0, 150, 136);border-left: 0.8em 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