{"id":56668,"date":"2024-06-16T18:14:21","date_gmt":"2024-06-16T10:14:21","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=56668"},"modified":"2024-06-16T18:14:21","modified_gmt":"2024-06-16T10:14:21","slug":"gwas%e7%9a%84meta%e5%88%86%e6%9e%90%ef%bc%9a%e6%8e%a7%e5%88%b6%e5%81%87%e9%98%b3%e7%9a%84%e5%b8%b8%e8%a7%81%e6%89%8b%e6%ae%b5%e4%b9%8b%e4%b8%80","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=56668","title":{"rendered":"GWAS\u7684meta\u5206\u6790\uff1a\u63a7\u5236\u5047\u9633\u7684\u5e38\u89c1\u624b\u6bb5\u4e4b\u4e00"},"content":{"rendered":"<p><html><br \/>\n<head><br \/>\n<title><\/title><br \/>\n<meta charset=\"utf-8\"><br \/>\n<meta name=\"viewport\" 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class=\"channels_iframe_wrp\"><mp-common-videosnap class=\"js_uneditable custom_select_card channels_live_iframe\" data-pluginname=\"mpvideosnap\" data-headimgurl=\"https:\/\/wx.qlogo.cn\/finderhead\/DX68kVlzcbz8hx9HMoThqGJzT37Slibt5l9fBMMKy3pg\/0\" data-username=\"v2_060000231003b20faec8c7e38019c0d4cc02ec33b077ef3bc1e59b4a7f53fd21ec5cd455628a@finder\" data-nickname=\"\u4e91\u751f\u4fe1\u5b66\u751f\u7269\u4fe1\u606f\u5b66\" data-desc=\"\u5c06\u572808\u670815\u65e5 15:00 \u76f4\u64ad\" data-livewording=\"\u9884\u7ea6\" data-intro=\"Seurat\u8fdb\u884c\u5355\u7ec6\u80de\u6d4b\u5e8f\u4e0b\u6e38\u5206\u6790\" data-type=\"live\" data-status=\"0\" data-noticeid=\"finderlivenotice-v2_060000231003b20faec8c7e38019c0d4cc02ec33b077ef3bc1e59b4a7f53fd21ec5cd455628a@finder-1691646609141418-1347608474\"><\/mp-common-videosnap><\/section>\n<p><span style=\"mso-spacerun:&quot;yes&quot;;font-family:\u5b8b\u4f53;mso-bidi-font-family:&quot;Times New 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\/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"font-size: 16px;\"><span style=\"font-size: 14px;\"><br  \/><\/span><\/p>\n<section style=\"\">\n<section data-id=\"22363\" powered-by=\"xmyeditor.com\" data-type=\"lspecial02\" data-md5=\"7ab9d\" style=\"font-size: 16px;\">\n<section style=\"text-align: left;\" powered-by=\"xmyeditor.com\" data-md5=\"7ab9d\">\n<section style=\"display: inline-block;vertical-align: middle;border-top: 1px dotted rgb(61, 170, 214);border-bottom: 1px dotted rgb(61, 170, 214);padding-right: 10px;padding-left: 10px;\" powered-by=\"xmyeditor.com\" data-md5=\"7ab9d\">\n<section powered-by=\"xmyeditor.com\" data-md5=\"7ab9d\">\n<p><strong><span style=\"color: rgb(0, 122, 170);\">1\u3001<\/span><\/strong><strong style=\"letter-spacing: 0.578px;\"><span style=\"color: rgb(0, 122, 170);\">\u5982\u4f55\u5224\u65ad\u7fa4\u4f53\u662f\u5426\u5206\u5c42<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section>\n<section style=\"margin-bottom: 0px;padding-right: 15px;padding-left: 15px;outline: 0px;font-size: 14px;visibility: visible;\">\n<section>\n<p><br  \/><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;\">\u9996\u5148\u4f7f\u7528plink\u8ba1\u7b97PCA\uff0c\u5177\u4f53\u65b9\u6cd5\u8be6\u89c1\u5c0f\u679c\u5f80\u671f\u516c\u4f17\u53f7\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;\">\u7ed8\u5236\u51fa\u4e0d\u540c\u7fa4\u4f53PC1\u3001PC2\u7684\u53cc\u6807\u56fe\u540e\uff0c\u5c31\u53ef\u4ee5\u89c2\u5bdf\u7fa4\u4f53\u4e4b\u95f4\u662f\u5426\u660e\u663e\u5206\u5f00\uff0c\u5982\u679c\u7fa4\u4f53\u660e\u663e\u5206\u5c42\u4e86\uff0c\u9700\u8981\u5355\u72ec\u8fdb\u884c\u5173\u8054\u5206\u6790\uff0c\u6700\u540e\u5728\u505ameta\u5206\u6790\u3002<\/span><span style=\"font-family: \u7b49\u7ebf;font-size: 10.5pt;letter-spacing: 0.578px;\"><\/span><\/p>\n<p><br  \/><\/p>\n<section>\n<section>\n<section>\n<section data-id=\"22363\" powered-by=\"xmyeditor.com\" data-type=\"lspecial02\" data-md5=\"7ab9d\" style=\"margin-bottom: 0px;letter-spacing: 0.578px;text-wrap: wrap;font-size: 16px;\">\n<section powered-by=\"xmyeditor.com\" data-md5=\"7ab9d\" style=\"text-align: left;\">\n<section powered-by=\"xmyeditor.com\" data-md5=\"7ab9d\" style=\"padding-right: 10px;padding-left: 10px;display: inline-block;vertical-align: middle;border-top: 1px dotted rgb(61, 170, 214);border-bottom: 1px dotted rgb(61, 170, 214);\">\n<section powered-by=\"xmyeditor.com\" data-md5=\"7ab9d\">\n<p><span style=\"color:#007aaa;\"><strong>2\u3001\u5982\u4f55\u505ameta\u5206\u6790<\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 10.5pt;\">\u8fd9\u91cc\u5c0f\u679c\u63a8\u8350\u4f7f\u7528metal\u8fdb\u884cmeta\u5206\u6790\uff0c\u539f\u56e0\u5f53\u7136\u662f\u7b80\u5355\u597d\u7528\uff0c\u8fd8\u6709windows\u7248\u5462\u3002\u4e0b\u8f7d\u94fe\u63a5\u5982\u4e0b\uff1a<\/span><span style=\"mso-spacerun:&#39;yes&#39;;font-family:&#39;Times New Roman&#39;;mso-fareast-font-family:\u5b8b\u4f53;font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"letter-spacing: 0.578px;text-decoration: underline;color: rgb(0, 122, 170);\">http:\/\/csg.sph.umich.edu\/abecasis\/metal\/download\/<\/span><br  \/><\/p>\n<p><o:p><\/o:p><span style=\"letter-spacing: 0.578px;\">metal<\/span><span style=\"letter-spacing: 0.578px;\">\u652f\u6301\u4e09\u4e2a\u5e73\u53f0\uff0c\u5c0f\u679c\u8fd9\u91cc\u8fd8\u662f\u4ee5\u6700\u5e38\u89c1\u7684<\/span><span style=\"letter-spacing: 0.578px;\">Linux<\/span><span style=\"letter-spacing: 0.578px;\">\u4e3e\u4f8b\uff0c\u4e0b\u8f7d\u547d\u4ee4\u5982\u4e0b\uff1a<\/span><\/p>\n<p><span style=\"color: rgb(0, 122, 170);letter-spacing: 0.578px;text-decoration: underline;\">wget<\/span><span style=\"letter-spacing: 0.578px;\"><\/span><\/p>\n<p><span style=\"color: rgb(0, 122, 170);letter-spacing: 0.578px;text-decoration: underline;\">http:\/\/csg.sph.umich.e<\/span><span style=\"color: rgb(0, 122, 170);letter-spacing: 0.578px;text-decoration: underline;\">du\/abecasis\/metal\/download\/Linux-metal.tar.gz<\/span><o:p><\/o:p><\/p>\n<p><span style=\"letter-spacing: 0.578px;\">\u89e3\u538b\u8f6f\u4ef6\uff1a<\/span><o:p><\/o:p><\/p>\n<p><span style=\"letter-spacing: 0.578px;color: rgb(0, 122, 170);text-decoration: underline;\">tar -zxvf Linux-metal.tar.gz<\/span><o:p><\/o:p><\/p>\n<p><span style=\"letter-spacing: 0.578px;\">\u5206\u6790\u7684\u6587\u4ef6\u6765\u6e90\u4e8emetal\u7684\u793a\u4f8b\u6570\u636e,\u89e3\u538b\u540e\u7684\u6587\u4ef6\u5939\u4e2d\u5305\u542b\u4e24\u4e2a\u793a\u4f8b\u6587\u4ef6,\u54b1\u4f7f\u7528.\/generic-metal\/examples\/GlucoseExample\u4e0b\u7684\u6570\u636e\u8fdb\u884c\u6f14\u793a<\/span><o:p><\/o:p><\/p>\n<p><span style=\"letter-spacing: 0.578px;\">\u793a\u4f8b\u6587\u4ef6\u4e2d\u8fd0\u884cmeta\u5206\u6790\u7684\u6587\u6863\u5206\u522b\u4e3aDGI_three_regions.txt\u548cmagic_SARDINIA.tbl\uff0c<\/span><o:p><\/o:p><\/p>\n<p><span style=\"letter-spacing: 0.578px;\">DGI_three_regions.txt\u5982\u4e0b\u6240\u793a<\/span><\/p>\n<p><span style=\"letter-spacing: 0.578px;\"><br  \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.16161616161616163\" data-s=\"300,640\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_CIJavf0icqW9SUUxibgPO62cfQFJzA.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAxenwVZiaibuOTpj6MMDUj2LoeDFxeGrbT9ur6GCUs7iaIBgAaFZCIJavf0icqW9SUUxibgPO62cfQFJzA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\"><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 10.5pt;\">magic_SARDINIA.tbl\u5982\u4e0b\u6240\u793a<\/span><span style=\"mso-spacerun:&#39;yes&#39;;font-family:&#39;Times New Roman&#39;;mso-fareast-font-family:\u5b8b\u4f53;font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 10.5pt;\"><br  \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.1673881673881674\" data-s=\"300,640\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_gRg6CKrwEzZ0kcnH8CnDDlspLKwmKQ.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAxenwVZiaibuOTpj6MMDUj2LoW8MurJaJ5RUAEUcMHLyOc80VgRg6CKrwEzZ0kcnH8CnDDlspLKwmKQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\"><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 10.5pt;\">\u8fd0\u884c\u5206\u6790\u524d\u9700\u8981\u51c6\u5907\u4e00\u4e2ametal.txt\u6587\u4ef6\uff0c\u5982\u4e0b\u56fe\u6240\u793a<\/span><span style=\"mso-spacerun:&#39;yes&#39;;font-family:&#39;Times New Roman&#39;;mso-fareast-font-family:\u5b8b\u4f53;font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"mso-spacerun:&#39;yes&#39;;font-family:\u5b8b\u4f53;mso-ascii-font-family:&#39;Times New Roman&#39;;mso-hansi-font-family:&#39;Times New Roman&#39;;mso-bidi-font-family:&#39;Times New Roman&#39;;font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><br  \/><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.8917748917748918\" data-s=\"300,640\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_zibBWs1Xha7kVEl0bNBaEHM0gWd1MQ.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAxenwVZiaibuOTpj6MMDUj2Loic64E3Hy4Hr2dkAvhx5UttkmJezibBWs1Xha7kVEl0bNBaEHM0gWd1MQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\"><\/p>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 10.5pt;\">\u5176\u4e2dMARKER\u5bf9\u5e94\u7684\u662fDGI_three_regions.txt\u6587\u6863\u7684SNP\u5217\u540d\uff1b<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 10.5pt;\">WEIGHT\u5bf9\u5e94\u7684\u662fDGI_three_regions.txt\u6587\u6863\u7684SNP\u5217\u540d\uff1b<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 10.5pt;\">\u5176\u4ed6\u7684\u4ee5\u6b64\u7c7b\u63a8\uff1b\u76f8\u5f53\u4e8emetal\u5206\u6790\u7684config\u6587\u4ef6\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 10.5pt;\">\u8fd0\u884c\u4ee3\u7801<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 10.5pt;\">metal metal.txt<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 10.5pt;\">\u8fdb\u884cmeta\u5206\u6790\uff0cmeta\u5206\u6790\u540e\u4f1a\u751f\u6210\u4e24\u4e2a\u6587\u4ef6\uff0c\u5206\u522b\u662fMETAANALYSIS1.TBL\u548c METAANALYSIS1.TBL.info<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><span style=\"font-size: 10.5pt;\">\u5176\u4e2dMETAANALYSIS1.TBL \u662fmeta\u5206\u6790\u7684\u7ed3\u679c\u6587\u6863\uff1b<\/span><span style=\"font-family: &quot;Times New Roman&quot;;font-size: 10.5pt;\"><o:p><\/o:p><\/span><\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.2453102453102453\" data-s=\"300,640\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_iblxBicJEYwydjsIRFN0XGMCUUzIFg.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAxenwVZiaibuOTpj6MMDUj2LooVCeMOr9evnjzCNqfwWp7ZDfMoiblxBicJEYwydjsIRFN0XGMCUUzIFg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\"><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;\">\u6211\u4eec\u4e00\u822c\u4e3b\u8981\u4e13\u6ce8meta\u5206\u6790\u540e\u7684pvalue\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;\">METAANALYSIS1.TBL.info\u6587\u4ef6\u4e3b\u8981\u662f\u5bf9METAANALYSIS1.TBL\u7684\u6ce8\u91ca\uff0c\u611f\u5174\u8da3\u7684\u53ef\u4ee5\u4ed4\u7ec6\u9605\u8bfb\u3002<\/span><\/p>\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;\"><br  \/><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.2222222222222222\" data-s=\"300,640\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_UtKKII54YLwicxiaJouibuicXFicaw.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAxenwVZiaibuOTpj6MMDUj2Lo07Cy5yLSFxg5IWJkfNZG6Xgj49xDTUtKKII54YLwicxiaJouibuicXFicaw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\"><\/p>\n<p><span style=\"font-size: 14px;font-family: \u5fae\u8f6f\u96c5\u9ed1;color: rgb(51, 51, 51);background: rgb(255, 255, 255);\"><\/span><\/p>\n<\/section>\n<\/section>\n<section style=\"font-size: 16px;\">\n<p><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 10.5pt;\">\u597d\u5566\uff0cmeta\u5206\u6790\u5230\u8fd9\u5c31\u7ed3\u675f\u4e86\uff0c\u5173\u6ce8\u5c0f\u679c\uff0c\u5c0f\u679c\u5e26\u4f60\u5b66\u4e60\u66f4\u591a\u751f\u4fe1\u5206\u6790\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;color: rgb(0, 122, 170);\">\u8fd9\u91cc\u63a8\u8350\u4e00\u4e0b\u5c0f\u679c\u65b0\u5f00\u53d1\u7684\u96f6\u4ee3\u7801\u4e91\u751f\u4fe1\u5206\u6790\u5de5\u5177\u5e73\u53f0\u5305\u542b\u8d85\u591a\u96f6\u4ee3\u7801\u5c0f\u5de5\u5177\uff0c\u4e0a\u4f20\u6570\u636e\u4e00\u952e\u51fa\u56fe\uff0c\u611f\u5174\u8da3\u7684\u5c0f\u4f19\u4f34\u6b22\u8fce\u4e86\u89e3~<\/span><\/p>\n<p><span style=\"font-size: 14px;color: rgb(0, 122, 170);\">\u7f51\u5740\uff1ahttp:\/\/www.biocloudservice.com\/home.html<\/span><\/p>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<section data-id=\"75061\" data-type=\"lspecial02\" data-tools=\"\u901f\u6392\u5c0f\u8682\u8681\u7f16\u8f91\u5668\" powered-by=\"xmyeditor.com\" data-md5=\"83a15\">\n<p><span style=\"font-size: 14px;\">\u4eca\u5929\u5c0f\u679c\u7684\u5206\u4eab\u5c31\u5230\u8fd9\u91cc\uff0c\u6b22\u8fce\u5927\u5bb6\u548c\u5c0f\u679c\u4e00\u8d77\u8ba8\u8bba\u5b66\u4e60\uff0c\u4e0b\u671f\u518d\u89c1\u54e6\uff01<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"outline: 0px;visibility: visible;\">\n<section style=\"outline: 0px;visibility: visible;\">\n<section style=\"padding-right: 15px;padding-left: 15px;outline: 0px;font-size: 14px;\">\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;height: auto;transform: perspective(0px);transform-style: flat;\">\n<section style=\"margin-top: 10px;margin-bottom: -3px;outline: 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