{"id":56693,"date":"2024-06-16T18:15:55","date_gmt":"2024-06-16T10:15:55","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=56693"},"modified":"2024-06-16T18:15:55","modified_gmt":"2024-06-16T10:15:55","slug":"%e8%bf%98%e5%9c%a8%e6%80%9d%e8%80%83%e9%a2%84%e5%90%8e%e6%a8%a1%e5%9e%8b%e9%9c%80%e8%a6%81%e9%82%a3%e4%ba%9b%e5%9b%be%ef%bc%9f%e5%b0%8f%e5%9b%be%e5%91%8a%e8%af%89%e4%bd%a0%e8%bf%98%e9%9c%80%e8%a6%81","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=56693","title":{"rendered":"\u8fd8\u5728\u601d\u8003\u9884\u540e\u6a21\u578b\u9700\u8981\u90a3\u4e9b\u56fe\uff1f\u5c0f\u56fe\u544a\u8bc9\u4f60\u8fd8\u9700\u8981\u68ee\u6797\u56fe\uff0c\u8bfa\u83ab\u56fe\uff0c\u6821\u51c6\u66f2\u7ebf\u4ee5\u53caDCA\u51b3\u7b56\u66f2\u7ebf\uff01\uff01\uff01"},"content":{"rendered":"


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normal;\">\u4e0d\u5c11\u505a\u764c\u75c7\u80bf\u7624\u75be\u75c5\u65b9\u5411\u7684\u5c0f\u4f19\u4f34\u90fd\u907f\u514d\u4e0d\u4e86\u8981\u53bb\u505a\u9884\u540e\u5206\u6790\uff0c\u65e2\u7136\u505a\u9884\u540e\u5206\u6790\uff0c\u80af\u5b9a\u5c11\u4e0d\u4e86\u6784\u5efa\u9884\u540e\u6a21\u578b\uff0c\u800c\u6709\u7684\u5c0f\u4f19\u4f34\u4ec5\u4ec5\u53ea\u662f\u628a\u9884\u540e\u7ed3\u679c\u505a\u51fa\u6765\uff0c\u4f46\u662f\u5374\u6ca1\u6709\u7ed8\u5236\u56fe\uff0c\u662f\u56e0\u4e3a\u5c0f\u4f19\u4f34\u4e0d\u77e5\u9053\u8be5\u7ed8\u5236\u90a3\u4e9b\u56fe\uff0c\u53bb\u53ef\u89c6\u5316\u81ea\u5df1\u7ed3\u679c\uff0c\u800c\u5f80\u5f80\u5c31\u662f\u68ee\u6797\u56fe\u7ed8\u5236\u5b8c\u5c31\u8349\u8349\u4e86\u4e8b\uff0c\u4f46\u662f\u5374\u5ffd\u7565\u4e86\u6a21\u578b\u7684\u610f\u4e49\u4ee5\u53ca\u6a21\u578b\u6784\u5efa\u662f\u597d\u8fd8\u662f\u574f\uff0c\u6240\u4ee5\uff0c\u5c0f\u56fe\u8fd9\u91cc\u6559\u5c0f\u4f19\u4f34\u7ed8\u5236\u68ee\u6797\u56fe\uff0c\u8bfa\u83ab\u56fe\uff0c\u6821\u51c6\u66f2\u7ebf\u4ee5\u53caDCA\u51b3\u7b56\u66f2\u7ebf\uff0c\u53bb\u9a8c\u8bc1\u81ea\u5df1\u6784\u5efa\u7684\u9884\u540e\u6a21\u578b\uff0c\u53ef\u89c6\u5316\u81ea\u5df1\u9884\u540e\u6a21\u578b\u7684\u7ed3\u679c\uff01\u4e0b\u9762\u8ddf\u7740\u5c0f\u56fe\u53bb\u5b66\u4e60\u5427\uff01<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">library(tidyverse)<\/span><\/code><code><span class=\"code-snippet_outer\">library(regplot)<\/span><\/code><code><span class=\"code-snippet_outer\">library(rms)<\/span><\/code><code><span class=\"code-snippet_outer\">library(survminer)<\/span><\/code><code><span class=\"code-snippet_outer\">library(survival)#\u6211\u4eec\u5728\u8fd9\u91cc\u8981\u8c03\u7528\u8fd9\u51e0\u4e2a\u5305\uff0c\u6709\u5904\u7406\u751f\u5b58\u6570\u636e\u7684\uff0c\u8fd8\u6709\u5bf9\u6570\u636e\u5f62\u5f0f\u8fdb\u884c\u5206\u6790\u7684<\/span><\/code><\/pre>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" 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data-ratio=\"0.2863741339491917\" data-s=\"300,640\" data-type=\"png\" data-w=\"433\" style=\"vertical-align: middle;width: 100%;height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_KMUefdL2FkdqIBerOFcaTXhbIu1Vzw.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsE0WHvkWry2FKeMAYHpVCtFibYlcZUP8CLEHWYKLv55BuZDKMUefdL2FkdqIBerOFcaTXhbIu1Vzw\/640?wx_fmt=png'\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.425\" data-s=\"300,640\" data-type=\"png\" data-w=\"560\" style=\"vertical-align: middle;width: 100%;height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_vKnwq4McRzVDsYWCfPrdhY82047vdQ.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsE0WHvkWry2FKeMAYHpVCtE2fY5BcuGia6kHWkCGVbtvyS3vKnwq4McRzVDsYWCfPrdhY82047vdQ\/640?wx_fmt=png'\" \/><\/section>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>Phe\u662f\u5206\u671f\u6570\u636e\u7b49<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.27624309392265195\" data-s=\"300,640\" data-type=\"png\" data-w=\"724\" style=\"vertical-align: middle;width: 100%;height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_MzFiaCyXodV7mUicmY4fj1Qn7ex5KQ.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsE0WHvkWry2FKeMAYHpVCtnbW06DO8ou9NyGA2QstFEWUJ5SMzFiaCyXodV7mUicmY4fj1Qn7ex5KQ\/640?wx_fmt=png'\" \/><\/section>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u98ce\u9669\u5f97\u5206\u5bf9\u5e94\u7684\u751f\u5b58\u72b6\u6001\u7b49<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"font-size: 15px;line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.415061295971979\" data-s=\"300,640\" data-type=\"png\" data-w=\"571\" style=\"vertical-align: middle;width: 100%;height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_bmKLlYEqzJl6HT200fwyohP7B1xN4A.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsE0WHvkWry2FKeMAYHpVCt38nNYK07ziaMdBoSODiapic0x6lbmKLlYEqzJl6HT200fwyohP7B1xN4A\/640?wx_fmt=png'\" \/><\/section>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u6700\u540e\u662f\u6837\u672c\u5bf9\u4e8e\u7684\u751f\u5b58\u72b6\u6001\u7b49<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.4700193423597679\" data-s=\"300,640\" data-type=\"png\" data-w=\"517\" style=\"vertical-align: middle;width: 100%;height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_s7CGXw9S3WQm5U34NzwCNdDfGpmj7A.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsE0WHvkWry2FKeMAYHpVCtME4L2v5ovyhPltfT8IL9J34ws7CGXw9S3WQm5U34NzwCNdDfGpmj7A\/640?wx_fmt=png'\" \/><\/section>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u6570\u636e\u51c6\u5907\u597d\u4e86\u6211\u4eec\u53bb\u7ed8\u5236\u628a\uff01<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"font-size: 15px;line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u6211\u4eec\u5148\u6784\u5efa\u591a\u56e0\u7d20\u7684\u68ee\u6797\u56fe<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"font-size: 15px;line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u8fd9\u91cc\u6211\u4eec\u5f97\u5230riskscore\u540e\uff0c\u4f7f\u7528\u591a\u56e0\u7d20COX\u6a21\u578b\u9a8c\u8bc1\u5176\u72ec\u7acb\u6027 ,\u7136\u540e\u4f7f\u7528ggforest\u51fd\u6570\u7ed8\u5236\u68ee\u6797\u56fe<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">riskScore_cli2 <- riskScore_cli %>% <\/span><\/code><code><span class=\"code-snippet_outer\">  inner_join(phe)<\/span><\/code><code><span class=\"code-snippet_outer\">head(riskScore_cli2)<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">#\u591a\u56e0\u7d20\u68ee\u6797\u56fe<\/span><\/code><code><span class=\"code-snippet_outer\">library(survminer)<\/span><\/code><code><span class=\"code-snippet_outer\">#\u6784\u5efa\u591a\u56e0\u7d20COX<\/span><\/code><code><span class=\"code-snippet_outer\">multiCox <- coxph(Surv(OS.time, OS) ~  age + gender +  tumor_stage + <\/span><\/code><code><span class=\"code-snippet_outer\">                    riskScore2,<\/span><\/code><code><span class=\"code-snippet_outer\">                  data = riskScore_cli2)<\/span><\/code><code><span class=\"code-snippet_outer\">multiCox<\/span><\/code><code><span class=\"code-snippet_outer\">#\u7ed8\u5236\u68ee\u6797\u56fe<\/span><\/code><code><span class=\"code-snippet_outer\">multicox_ggforest <- ggforest(multiCox,  <span class=\"code-snippet__meta\">#coxph\u5f97\u5230\u7684Cox\u56de\u5f52\u7ed3\u679c<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">                              data = riskScore_cli2,  #\u6570\u636e\u96c6<\/span><\/code><code><span class=\"code-snippet_outer\">                              main = <span class=\"code-snippet__string\">'Hazard ratio of multi cox'<\/span>,  #\u6807\u9898<\/span><\/code><code><span class=\"code-snippet_outer\">                              cpositions = c(<span class=\"code-snippet__number\">0.05<\/span>, <span class=\"code-snippet__number\">0.15<\/span>, <span class=\"code-snippet__number\">0.35<\/span>),  #\u524d\u4e09\u5217\u8ddd\u79bb<\/span><\/code><code><span class=\"code-snippet_outer\">                              fontsize = <span class=\"code-snippet__number\">0.8<\/span>, #\u5b57\u4f53\u5927\u5c0f<\/span><\/code><code><span class=\"code-snippet_outer\">                              refLabel = <span class=\"code-snippet__string\">'reference'<\/span>, #\u76f8\u5bf9\u53d8\u91cf\u7684\u6570\u503c\u6807\u7b7e\uff0c\u4e5f\u53ef\u6539\u4e3a<span class=\"code-snippet__number\">1<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">                              noDigits = <span class=\"code-snippet__number\">3<\/span> #\u4fdd\u7559HR\u503c\u4ee5\u53ca<span class=\"code-snippet__number\">95<\/span>%CI\u7684\u5c0f\u6570\u4f4d\u6570<\/span><\/code><code><span class=\"code-snippet_outer\">)<\/span><\/code><code><span class=\"code-snippet_outer\">multicox_ggforest<\/span><\/code><\/pre>\n<\/section>\n<section style=\"font-size: 15px;line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u4e0a\u8ff0\u4ee3\u7801\u5c0f\u56fe\u90fd\u6709\u5907\u6ce8\uff0c\u5c0f\u4f19\u4f34\u8981\u4ed4\u7ec6\u67e5\u770b<\/p>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.9908536585365854\" data-s=\"300,640\" data-type=\"png\" data-w=\"656\" style=\"vertical-align: middle;width: 100%;height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_rWicvLcgpld9XyPR9gdhUQkd7nrJLg.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsE0WHvkWry2FKeMAYHpVCtRDRLSgjanHJ8Yr2kObnScQO6RrWicvLcgpld9XyPR9gdhUQkd7nrJLg\/640?wx_fmt=png'\" \/><\/section>\n<\/section>\n<section style=\"font-size: 15px;line-height: 1.8;letter-spacing: 1px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u7b80\u5355\u7684\u68ee\u6797\u56fe\u5c31\u7ed8\u5236\u5b8c\u6210\u4e86\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">\u540e\u9762\u5c31\u662f\u8bfa\u83ab\u56fe\u4e5f\u5c31\u662fNomogram\uff0c\u901a\u5e38\u4e5f\u88ab\u79f0\u4e3a\u5217\u7ebf\u56fe\uff0c\u5e38\u7528\u4e8e\u8bc4\u4f30\u80bf\u7624\u5b66\u548c\u533b\u5b66\u7684\u9884\u540e\u60c5\u51b5\u3002<\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u53ef\u5c06Cox\u56de\u5f52\u7684\u7ed3\u679c\u8fdb\u884c\u53ef\u89c6\u5316\u3002<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#nomogram<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">dd=datadist(riskScore_cli2)<\/span><\/code><code><span class=\"code-snippet_outer\">options(datadist=<span class=\"code-snippet__string\">\"dd\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">## \u6784\u5efaCOX\u6bd4\u4f8b\u98ce\u9669\u6a21\u578b<\/span><\/code><code><span class=\"code-snippet_outer\">f <- psm(Surv(OS.time,OS) ~ age + gender +  tumor_stage + riskScore2,<\/span><\/code><code><span class=\"code-snippet_outer\">         data = riskScore_cli2,dist=<span class=\"code-snippet__string\">'lognormal'<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">surv <- Survival(f) # \u6784\u5efa\u751f\u5b58\u6982\u7387\u51fd\u6570<\/span><\/code><code><span class=\"code-snippet_outer\">#<span class=\"code-snippet__meta\"># time\u662f\u4ee5\u201d\u5929\u201c\u4e3a\u5355\u4f4d,\u6b64\u5904\u7ed8\u52361\u5e74\uff0c3,5\u5e74\u7684\u751f\u5b58\u6982\u7387<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">nom <- nomogram(f, fun=<span class=\"code-snippet__built_in\">list<\/span>(function(x) surv(<span class=\"code-snippet__number\">365<\/span>, x),<\/span><\/code><code><span class=\"code-snippet_outer\">                            function(x) surv(<span class=\"code-snippet__number\">1095<\/span>, x),<\/span><\/code><code><span class=\"code-snippet_outer\">                            function(x) surv(<span class=\"code-snippet__number\">1825<\/span>, x) ),<\/span><\/code><code><span class=\"code-snippet_outer\">                funlabel=c(<span class=\"code-snippet__string\">\"1-year OS\"<\/span>, <span class=\"code-snippet__string\">\"3-year OS\"<\/span>, <\/span><\/code><code><span class=\"code-snippet_outer\">                           <span class=\"code-snippet__string\">\"5-year OS\"<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\">plot(nom, xfrac=<span class=\"code-snippet__number\">.2<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.896875\" data-s=\"300,640\" data-type=\"png\" data-w=\"640\" style=\"vertical-align: middle;width: 100%;height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_FrYBloib1BMfX1kTJXMcRjnwtia0kA.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsE0WHvkWry2FKeMAYHpVCtCBGiamrrsTvWNwboXmaDTwNSCvuFrYBloib1BMfX1kTJXMcRjnwtia0kA\/640?wx_fmt=png'\" \/><\/section>\n<\/section>\n<section style=\"font-size: 15px;line-height: 1.8;letter-spacing: 1px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u5c0f\u4f19\u4f34\u770b\u8d77\u6765\u662f\u4e0d\u662f\u6709\u70b9\u5355\u8c03\uff0c\u770b\u4f3c\u53ea\u6709\u7ebf\u6761\u4e00\u6837\uff0c<\/p>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u5c0f\u56fe\u8fd9\u91cc\u53e6\u4e00\u79cd\u7ed8\u5236\u65b9\u6cd5\u5b9e\u9a8cregplot\u7ed8\u5236<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#regplot<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">library(regplot)<\/span><\/code><code><span class=\"code-snippet_outer\">Cox_nomo2 <- cph(Surv(OS.time, OS) ~ age + gender + tumor_stage  + riskScore2,<\/span><\/code><code><span class=\"code-snippet_outer\">                 data = riskScore_cli2, x=T, y=T)<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">regplot(Cox_nomo2, <\/span><\/code><code><span class=\"code-snippet_outer\">        observation = riskScore_cli2[<span class=\"code-snippet__number\">4<\/span>,], #\u6307\u5b9a\u67d0\u4e00\u60a3\u8005<\/span><\/code><code><span class=\"code-snippet_outer\">        interval =<span class=\"code-snippet__string\">\"confidence\"<\/span>, <\/span><\/code><code><span class=\"code-snippet_outer\">        title=<span class=\"code-snippet__string\">\"Nomogram\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">        plots=c(<span class=\"code-snippet__string\">\"violin\"<\/span>, <span class=\"code-snippet__string\">\"boxes\"<\/span>), <\/span><\/code><code><span class=\"code-snippet_outer\">        clickable = T,<\/span><\/code><code><span class=\"code-snippet_outer\">        failtime = c(<span class=\"code-snippet__number\">365<\/span>,<span class=\"code-snippet__number\">1095<\/span>,<span class=\"code-snippet__number\">1825<\/span>)) #\u8bbe\u7f6e\u968f\u8bbf\u65f6\u95f4<span class=\"code-snippet__number\">1<\/span>\u5e74\u3001<span class=\"code-snippet__number\">3<\/span>\u5e74\u548c<span class=\"code-snippet__number\">5<\/span>\u5e74<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.6566265060240963\" data-s=\"300,640\" data-type=\"png\" data-w=\"996\" style=\"vertical-align: middle;width: 100%;height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_aLdK3wibe7iaayJvWV5XfbKSkSWibA.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsE0WHvkWry2FKeMAYHpVCtIbz93zpvMANW3rwLyEsONicccpxlaLdK3wibe7iaayJvWV5XfbKSkSWibA\/640?wx_fmt=png'\" \/><\/section>\n<\/section>\n<section style=\"font-size: 15px;line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u662f\u4e0d\u662f\u7acb\u9a6c\u4e0d\u4e00\u6837\u4e86 \u597d\u770b\u7684\u4e0d\u884c\uff0c\u6bcf\u4e00\u79cd\u7279\u6027\u90fd\u5c55\u793a\u5f88\u6e05\u695a\u3002<\/p>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u63a5\u4e0b\u6765\u6211\u4eec\u53bb\u7ed8\u5236\u6821\u51c6\u66f2\u7ebf<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"font-size: 15px;line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u4e00\u822c\u6765\u8bf4\uff0c\u6211\u4eec\u7ed8\u52361 ,3, 5\u5e74\u7684\u6821\u51c6\u66f2\u7ebf\uff0c\u5c0f\u4f19\u4f34\u8981\u6ce8\u610fm\u503c\u6839\u636e\u6837\u672c\u6570\u91cf\u9009\u62e9\uff0c\u4f53\u73b0\u5728\u56fe\u4e2d\u591a\u5c11errbar \uff0c\u5927\u6982\u9009\u62e91\/3 \u6216\u80051\/4\u5373\u53ef\u3002\u6211\u4eec\u5148\u8ba1\u7b97\u4e00\u4e0b<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#<span class=\"code-snippet__number\">1<\/span>-year<\/span><\/code><code><span class=\"code-snippet_outer\">cox1 <- cph(Surv(OS.time,OS) ~ age + gender +  tumor_stage + riskScore2,<\/span><\/code><code><span class=\"code-snippet_outer\">            surv=T,x=T, y=T,time.inc = <span class=\"code-snippet__number\">1<\/span>*<span class=\"code-snippet__number\">365<\/span>,data=riskScore_cli2)<\/span><\/code><code><span class=\"code-snippet_outer\">cal <- calibrate(cox1, cmethod=<span class=\"code-snippet__string\">\"KM\"<\/span>, method=<span class=\"code-snippet__string\">\"boot\"<\/span>, u=<span class=\"code-snippet__number\">1<\/span>*<span class=\"code-snippet__number\">365<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">                 m= <span class=\"code-snippet__number\">100<\/span>, B=<span class=\"code-snippet__number\">1000<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">#<span class=\"code-snippet__number\">3<\/span>-year<\/span><\/code><code><span class=\"code-snippet_outer\">cox3 <- cph(Surv(OS.time,OS) ~ age + gender +  tumor_stage + riskScore2,<\/span><\/code><code><span class=\"code-snippet_outer\">            surv=T,x=T, y=T,time.inc = <span class=\"code-snippet__number\">1<\/span>*<span class=\"code-snippet__number\">365<\/span>*<span class=\"code-snippet__number\">3<\/span>,data=riskScore_cli2)<\/span><\/code><code><span class=\"code-snippet_outer\">ca3 <- calibrate(cox3, cmethod=<span class=\"code-snippet__string\">\"KM\"<\/span>, method=<span class=\"code-snippet__string\">\"boot\"<\/span>, u=<span class=\"code-snippet__number\">1<\/span>*<span class=\"code-snippet__number\">365<\/span>*<span class=\"code-snippet__number\">3<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">                 m= <span class=\"code-snippet__number\">100<\/span>, B=<span class=\"code-snippet__number\">1000<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">#<span class=\"code-snippet__number\">5<\/span>-year<\/span><\/code><code><span class=\"code-snippet_outer\">cox5 <- cph(Surv(OS.time,OS) ~ age + gender +  tumor_stage + riskScore2,<\/span><\/code><code><span class=\"code-snippet_outer\">            surv=T,x=T, y=T,time.inc = <span class=\"code-snippet__number\">1<\/span>*<span class=\"code-snippet__number\">365<\/span>*<span class=\"code-snippet__number\">5<\/span>,data=riskScore_cli2)<\/span><\/code><code><span class=\"code-snippet_outer\">ca5 <- calibrate(cox5, cmethod=<span class=\"code-snippet__string\">\"KM\"<\/span>, method=<span class=\"code-snippet__string\">\"boot\"<\/span>, u=<span class=\"code-snippet__number\">1<\/span>*<span class=\"code-snippet__number\">365<\/span>*<span class=\"code-snippet__number\">5<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">                 m= <span class=\"code-snippet__number\">100<\/span>, B=<span class=\"code-snippet__number\">1000<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u53ef\u89c6\u5316\u7ed3\u679c<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"font-size: 15px;line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u5c0f\u4f19\u4f34\u53ef\u4ee5\u6839\u636e\u9009\u62e9\u53bb\u7ed8\u5236\u5355\u6761\u8fd8\u662f\u53cc\u6761\u8fd9\u91cc\uff0c\u4f7f\u7528plot\u51fd\u6570\u8fdb\u884c\u53ef\u89c6\u5316\uff0c\u5c0f\u4f19\u4f34\u5982\u679c\u60f31\uff0c3\uff0c5\u5e74\u7684\u6821\u51c6\u66f2\u7ebf\u7ed8\u5236\u5728\u4e00\u5f20\u56fe\u4e2d\uff0c\u4f7f\u7528add = T\u5c31\u53ef\u4ee5\uff0c\u4f46\u662f\u8981\u6ce8\u610f\u8c03\u8282xlim \u548c ylim \u7684\u8303\u56f4 \u3002<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u7ed8\u5236\u5355\u6761<\/span><\/code><code><span class=\"code-snippet_outer\">plot(cal,lwd=<span class=\"code-snippet__number\">2<\/span>,lty=<span class=\"code-snippet__number\">1<\/span>,errbar.col=<span class=\"code-snippet__string\">\"black\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">     xlab =<span class=\"code-snippet__string\">\"Nomogram-Predicted Probability of 1-Year Survival\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">     ylab=<span class=\"code-snippet__string\">\"Actual 1-Year Survival\"<\/span>,col=<span class=\"code-snippet__string\">\"blue\"<\/span>,sub=F)<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">#\u591a\u6761<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">plot(cal,lwd=<span class=\"code-snippet__number\">2<\/span>,lty=<span class=\"code-snippet__number\">1<\/span>,errbar.col=<span class=\"code-snippet__string\">\"black\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">     xlim = c(<span class=\"code-snippet__number\">0.5<\/span>,<span class=\"code-snippet__number\">1<\/span>) ,<\/span><\/code><code><span class=\"code-snippet_outer\">     ylim = c(<span class=\"code-snippet__number\">0.4<\/span>,<span class=\"code-snippet__number\">1<\/span>), <\/span><\/code><code><span class=\"code-snippet_outer\">     xlab =<span class=\"code-snippet__string\">\"Nomogram-Predicted Probability of 1,3,5Year Survival\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">     ylab=<span class=\"code-snippet__string\">\"Actual 1,3,5Year Survival\"<\/span>,col=<span class=\"code-snippet__string\">\"blue\"<\/span>,sub=F)<\/span><\/code><code><span class=\"code-snippet_outer\">plot(ca3,<\/span><\/code><code><span class=\"code-snippet_outer\">     add = T ,<\/span><\/code><code><span class=\"code-snippet_outer\">     lwd=<span class=\"code-snippet__number\">2<\/span>,lty=<span class=\"code-snippet__number\">1<\/span>,errbar.col=<span class=\"code-snippet__string\">\"black\"<\/span>,col=<span class=\"code-snippet__string\">\"red\"<\/span>,sub=F)<\/span><\/code><code><span class=\"code-snippet_outer\">plot(ca5,<\/span><\/code><code><span class=\"code-snippet_outer\">     add = T ,<\/span><\/code><code><span class=\"code-snippet_outer\">     lwd=<span class=\"code-snippet__number\">2<\/span>,lty=<span class=\"code-snippet__number\">1<\/span>,errbar.col=<span class=\"code-snippet__string\">\"black\"<\/span>,col=<span class=\"code-snippet__string\">\"green\"<\/span>,sub=F)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.6495901639344263\" data-s=\"300,640\" data-type=\"png\" data-w=\"976\" style=\"vertical-align: middle;width: 100%;height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_tZzafTzAzlBfL7CeqYGggluicSgftw.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsE0WHvkWry2FKeMAYHpVCtjicIRplXAUXibPvvicSalXTrf4aMtZzafTzAzlBfL7CeqYGggluicSgftw\/640?wx_fmt=png'\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.6506639427987743\" data-s=\"300,640\" data-type=\"png\" data-w=\"979\" style=\"vertical-align: middle;width: 100%;height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/10_Cibiabrvosibf9Ax5nJMiaic4zjMAQ.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsE0WHvkWry2FKeMAYHpVCtiaaW2HLmmX78oTAEwmFpCocCVbsKGoCibiabrvosibf9Ax5nJMiaic4zjMAQ\/640?wx_fmt=png'\" \/><\/section>\n<\/section>\n<section style=\"font-size: 15px;line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u4e0a\u8ff0\u5c31\u662f\u5355\u6761\u548c\u591a\u6761\uff0c\u5c0f\u4f19\u4f34\u81ea\u884c\u9009\u62e9<\/p>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u6700\u540e\u5462\u6211\u4eec\u53bb\u7ed8\u5236DCA\u51b3\u7b56\u66f2\u7ebf\uff1a<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#DCA\u51b3\u7b56\u66f2\u7ebf<\/span><\/code><code><span class=\"code-snippet_outer\">library(caret)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#install.packages(<span class=\"code-snippet__meta-string\">\"devtools\"<\/span>)<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#options(unzip = <span class=\"code-snippet__meta-string\">'internal'<\/span>)<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#devtools::install_github(<span class=\"code-snippet__meta-string\">'yikeshu0611\/ggDCA'<\/span>)#\u5c0f\u4f19\u4f34\u8981\u6ce8\u610f\uff0c\u8fd9\u4e2a\u5305\u4e0d\u662f\u5f88\u597d\u4e0b\uff0c\u53ef\u4ee5\u7528\u8fd9\u4e2a\u65b9\u5f0f\u8bd5\u8bd5<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">library(ggDCA)<\/span><\/code><code><span class=\"code-snippet_outer\">Cox_nomo2<-rms::cph(Surv(OS.time, OS) ~ age + gender + tumor_stage  + riskScore2,<\/span><\/code><code><span class=\"code-snippet_outer\">                    data = riskScore_cli2)<\/span><\/code><code><span class=\"code-snippet_outer\">d_train <- dca(Cox_nomo2,<\/span><\/code><code><span class=\"code-snippet_outer\">               times=<span class=\"code-snippet__number\">1800<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">ggplot(d_train)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"1.0968992248062015\" data-s=\"300,640\" data-type=\"png\" data-w=\"516\" style=\"vertical-align: middle;width: 100%;height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/11_jGKGK03fGyhhIN3mwX3SBVEhSn1CGw.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsE0WHvkWry2FKeMAYHpVCt4HItNk4Z3Zp2eDZEewY32W11jGKGK03fGyhhIN3mwX3SBVEhSn1CGw\/640?wx_fmt=png'\" \/><\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.3888888888888889\" data-s=\"300,640\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/12_l5aJva4luEuCyuWJJv1Wq96vPIRkWQ.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsE0WHvkWry2FKeMAYHpVCt4B3a5iamDMzicmP6zhEm0h1qxZl5aJva4luEuCyuWJJv1Wq96vPIRkWQ\/640?wx_fmt=png'\" \/><\/section>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-bottom: 10px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(176, 176, 176);padding: 7px;\">\n<section style=\"justify-content: flex-start;display: flex;flex-flow: row;\" 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