{"id":56708,"date":"2024-06-16T18:16:43","date_gmt":"2024-06-16T10:16:43","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=56708"},"modified":"2024-06-16T18:16:43","modified_gmt":"2024-06-16T10:16:43","slug":"%e7%aa%81%e7%a0%b4%e6%83%b3%e8%b1%a1%ef%bc%8c%e8%af%a5%e6%9c%89%e7%9a%84%e7%83%ad%e7%82%b9%e4%b8%80%e4%b8%aa%e4%b8%8d%e8%90%bd%e4%b8%8b%ef%bc%81%e8%b4%b5%e5%b7%9e%e7%9c%81%e4%ba%ba%e6%b0%91%e5%8c%bb","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=56708","title":{"rendered":"\u7a81\u7834\u60f3\u8c61\uff0c\u8be5\u6709\u7684\u70ed\u70b9\u4e00\u4e2a\u4e0d\u843d\u4e0b\uff01\u8d35\u5dde\u7701\u4eba\u6c11\u533b\u9662\u56e2\u961f7\u5206+\uff1a\u5b5f\u5fb7\u5c14\u968f\u673a\u5316+\u7f51\u7edc\u836f\u7406\u5b66+\u83cc\u7fa4+\u5355\u7ec6\u80de+\u5206\u5b50\u5bf9\u63a5\uff0c\u4eba\u751f\u8d62\u5bb6\uff01"},"content":{"rendered":"


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bold;\">\u5982\u4f55\u63a8\u9648\u51fa\u65b0\uff1f\u627e\u51fa\u4e00\u4e2a\u8ba9\u5ba1\u7a3f\u4eba\u773c\u524d\u4e00\u4eae\u7684\u521b\u65b0\u70b9\u5462\uff1f\u5982\u679c\u4f60\u4e5f\u5bf9\u8fd9\u4e2a\u611f\u5174\u8da3\u7684\u8bdd\uff0c\u63a5\u4e0b\u6765\u5c31\u8ddf\u7740\u5c0f\u9014\u4e00\u8d77\u770b\u770b\u4eca\u5929\u8fd9\u7bc7\u6587\u7ae0\u5427~<\/span><\/span><\/section>\n<section style=\"text-align: justify;margin-left: 21pt;line-height: 120%;font-size: 12pt;font-family: "Times New Roman";font-weight: bold;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(0, 0, 0);\">1.<\/span><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 255);\">\u9996\u6b21\u91c7\u7528MR\u6765\u7814\u7a76\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u4e0e\u8d25\u8840\u75c7\u4e4b\u95f4\u7684\u5173\u7cfb\uff1a<\/span><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 0);\">\u4f7f\u7528\u6700\u5927\u89c4\u6a21\u7684\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u548c\u8d25\u8840\u75c7GWAS\u835f\u8403\u5206\u6790\u7684\u6c47\u603b\u7edf\u8ba1\u6570\u636e\uff0c\u8fdb\u884c\u4e86\u4e24\u6837\u672cMR\u5206\u6790\uff0c\u8bc4\u4f30\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u4e0e\u8d25\u8840\u75c7\u53ca\u5176\u76f8\u5173\u75be\u75c5\u4e4b\u95f4\u7684\u56e0\u679c\u5173\u7cfb\u3002\u8fd9\u79cd\u65b9\u6cd5\u80fd\u591f\u5728\u4e00\u4e2a\u7edf\u4e00\u7684\u6846\u67b6\u5185\u8bc4\u4f30\u5fae\u751f\u7269\u7fa4\u5982\u4f55\u5f71\u54cd\u8d25\u8840\u75c7\uff0c\u63ed\u793a\u6f5c\u5728\u7684\u751f\u7269\u5b66\u673a\u5236\u3002<\/span><\/span><\/section>\n<section style=\"text-align: justify;margin-left: 21pt;line-height: 120%;font-size: 12pt;font-family: "Times New Roman";font-weight: bold;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(13, 13, 13);\">2.<\/span><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 255);\">\u57fa\u4e8e\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u6d4b\u5e8f\u8054\u5408\u6279\u91cfRNA\u6d4b\u5e8f\u6df1\u5165\u673a\u5236\u7814\u7a76\uff1a<\/span><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u8fd9\u9879\u7814\u7a76\u6574\u5408\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u5b66\u548c\u5927\u91cfRNA\u6d4b\u5e8f\u6280\u672f\uff0c\u5168\u9762\u9610\u660e\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u5728\u8d25\u8840\u75c7\u53d1\u5c55\u4e2d\u7684\u6f5c\u5728\u673a\u5236\uff0c\u6df1\u5165\u4e86\u89e3\u76f8\u5173\u57fa\u56e0\u5728\u8113\u6bd2\u75c7\u53d1\u5c55\u4e2d\u7684\u529f\u80fd\u548c\u8c03\u63a7\u673a\u5236\u548c\u4e0d\u540c\u75c5\u7406\u72b6\u6001\u4e0b\u7684\u8868\u8fbe\u53d8\u5316\u3002<\/span><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(255, 0, 0);\">\u770b\u5b8c\u4e86\u522b\u4eba\u7684\u521b\u65b0\u70b9\u89c9\u5f97\u8d85\u7ea7nice\u5e76\u4e14\u8dc3\u8dc3\u6b32\u8bd5\uff1f\u81ea\u5df1\u52a8\u624b\u64cd\u4f5c\u7684\u65f6\u5019\u5374\u53d1\u73b0\u8111\u5b50\u4f1a\u4e86\u624b\u5374\u4e0d\u4f1a\uff1f\u5982\u679c\u4f60\u4e5f\u662f\u8fd9\u6837\u7684\u8bdd\uff0c\u5feb\u6765\u627e\u5c0f\u9014\uff01\u5c0f\u9014\u613f\u610f\u505a\u4f60\u505a\u4f60\u79d1\u7814\u8def\u4e0a\u7684\u8d77\u98de\u5c0f\u52a9\u624b~<\/span>    <\/span><\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" data-s=\"300,640\" data-imgfileid=\"100018513\" class=\"rich_pages wxw-img\" style=\"width: 180px;height: auto !important;\" data-type=\"jpeg\" data-ratio=\"1\" data-w=\"430\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_B2jkicacLzPjw4xMSqVvoucZjonVDA-47.jpg\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAxVYfSsM0wdf9d3RpNiaTcHohxPNEVs2VFhPMukpU8lchxrvcB2jkicacLzPjw4xMSqVvoucZjonVDA\/640?wx_fmt=jpeg'\" \/><\/p>\n<section style=\"text-align: justify;margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(13, 13, 13);background: rgb(255, 255, 255);font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100011493\" data-ratio=\"0.49201277955271566\" data-type=\"png\" data-w=\"939\" height=\"272.3999938964844\" width=\"553.739990234375\" style=\"height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_XWTY1eycqyhuLM1yTIqMqK0EqqOuhA.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTT148UKrrdRGcOEvqFA1ZatZNuF1zJkiaZDlkh3jYAb3452XWTY1eycqyhuLM1yTIqMqK0EqqOuhA\/640?wx_fmt=png'\" \/> <\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u9898\u76ee\uff1a\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u5bf9\u8d25\u8840\u75c7\u548c\u8d25\u8840\u75c7\u76f8\u5173\u6b7b\u4ea1\u7684\u56e0\u679c\u6548\u5e94\uff1a\u4ece\u5168\u57fa\u56e0\u7ec4\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u3001\u5355\u7ec6\u80de RNA\u3001\u5927\u91cf RNA \u6d4b\u5e8f\u548c\u7f51\u7edc\u836f\u7406\u5b66\u4e2d\u83b7\u5f97\u7684\u542f\u793a<\/span><\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u6742\u5fd7\uff1aJournal of Translational Medicine<\/span><\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u5f71\u54cd\u56e0\u5b50\uff1aIF=7.4<\/span><\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u53d1\u8868\u65f6\u95f4\uff1a2024\u5e741\u6708<\/span><\/span><\/section>\n<section style=\"font-size: 16px;margin-bottom: 0px;\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;height: auto;\">\n<section style=\"transform: perspective(0px);transform-style: flat;\">\n<section style=\"transform: rotateY(180deg);\">\n<section style=\"display: inline-block;vertical-align: top;overflow: hidden;height: 0px;width: 0px;border-style: solid;border-width: 0px 10px 44px 0px;border-color: rgba(255, 255, 255, 0) rgba(255, 255, 255, 0) rgb(71, 193, 168);\">\n<section style=\"text-align: justify;\">\n<p style=\"text-wrap: wrap;\"><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: stretch;flex: 0 0 auto;min-width: 5%;height: auto;padding: 8px 11px;background-color: rgb(71, 193, 168);\">\n<section style=\"text-align: left;transform: translate3d(-4px, 0px, 0px);\">\n<section style=\"text-align: justify;color: rgb(255, 255, 255);\">\n<p style=\"text-align: left;text-wrap: wrap;\"><span style=\"font-size: 20px;\"><strong>\u7814\u7a76\u80cc\u666f<\/strong><\/span><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;align-self: stretch;flex: 0 0 auto;min-width: 5%;height: auto;line-height: 0.1;margin-left: -10px;\">\n<section style=\"display: flex;width: 100%;flex-flow: column;\">\n<section style=\"z-index: 1;\">\n<section style=\"text-align: left;\">\n<section style=\"display: inline-block;width: 0px;height: 0px;vertical-align: top;overflow: hidden;border-style: solid;border-width: 0px 10px 44px;border-color: rgba(255, 255, 255, 0) rgba(255, 255, 255, 0) rgb(255, 205, 104);\">\n<section style=\"text-align: justify;\">\n<p style=\"text-wrap: wrap;\"><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-bottom: 0px;\"><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;text-indent: 0em;letter-spacing: 0.034em;font-variant-numeric: normal;font-variant-east-asian: normal;font-variant-alternates: normal;font-variant-position: normal;\">\u8113\u6bd2\u75c7\u662f\u4e00\u79cd\u4e25\u91cd\u7684\u4f20\u67d3\u75c5\uff0c\u5728\u5168\u7403\u8303\u56f4\u5185\u7684\u53d1\u75c5\u7387\u548c\u6b7b\u4ea1\u7387\u90fd\u5728\u4e0a\u5347\uff0c\u5bf9\u516c\u5171\u536b\u751f\u9886\u57df\u6784\u6210\u4e86\u91cd\u5927\u6311\u6218\u3002\u80a0\u9053\u83cc\u7fa4\u5931\u8c03\u4e0e\u8113\u6bd2\u75c7\u7b49\u591a\u79cd\u75be\u75c5\u7684\u53d1\u751f\u53d1\u5c55\u5bc6\u5207\u76f8\u5173\u3002\u7136\u800c\uff0c\u76ee\u524d\u5173\u4e8e\u8113\u6bd2\u75c7\u4e0e\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u4e4b\u95f4\u5173\u7cfb\u7684\u7814\u7a76\u5b58\u5728\u4e00\u4e9b\u5c40\u9650\u6027\u3002\u9996\u5148\uff0c\u6211\u4eec\u5bf9\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u7684\u7ec4\u6210\u548c\u529f\u80fd\u7684\u4e86\u89e3\u4ecd\u7136\u6709\u9650\uff0c\u4e0d\u540c\u5fae\u751f\u7269\u79cd\u7fa4\u7684\u6f5c\u5728\u673a\u5236\u53ca\u5176\u4e0e\u8113\u6bd2\u75c7\u7684\u5173\u8054\u5c1a\u672a\u5b8c\u5168\u9610\u660e\u3002\u5176\u6b21\uff0c\u7f3a\u4e4f\u5927\u89c4\u6a21\u3001\u591a\u4e2d\u5fc3\u7684\u4e34\u5e8a\u7814\u7a76\u6570\u636e\uff0c\u5bfc\u81f4\u5bf9\u4e0d\u540c\u60a3\u8005\u7fa4\u4f53\u80a0\u9053\u83cc\u7fa4\u4e0e\u8113\u6bd2\u75c7\u4e4b\u95f4\u5173\u7cfb\u7684\u7406\u89e3\u4e0d\u5b8c\u6574\u548c\u4e0d\u51c6\u786e\u3002\u6b64\u5916\uff0c\u7531\u4e8e\u7814\u7a76\u65b9\u6cd5\u7684\u5c40\u9650\u6027\uff0c\u80a0\u9053\u83cc\u7fa4\u4e0e\u8113\u6bd2\u75c7\u4e4b\u95f4\u7684\u56e0\u679c\u5173\u7cfb\u53ca\u5176\u5728\u8113\u6bd2\u75c7\u9884\u9632\u548c\u6cbb\u7597\u4e2d\u7684\u6f5c\u5728\u5e94\u7528\u5c1a\u672a\u5f97\u5230\u5e7f\u6cdb\u7814\u7a76\u3002<\/span><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;text-indent: 0em;letter-spacing: 0.034em;\">    <\/span><br \/><\/p>\n<section style=\"font-size: 16px;margin-bottom: 0px;\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;height: auto;\">\n<section style=\"transform: perspective(0px);transform-style: flat;\">\n<section style=\"transform: rotateY(180deg);\">\n<section style=\"display: inline-block;vertical-align: top;overflow: hidden;height: 0px;width: 0px;border-style: solid;border-width: 0px 10px 44px 0px;border-color: rgba(255, 255, 255, 0) rgba(255, 255, 255, 0) rgb(71, 193, 168);\">\n<section style=\"text-align: justify;\">\n<p style=\"text-wrap: wrap;\"><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: stretch;flex: 0 0 auto;min-width: 5%;height: auto;padding: 8px 11px;background-color: rgb(71, 193, 168);\">\n<section style=\"text-align: left;transform: translate3d(-4px, 0px, 0px);\">\n<section style=\"text-align: justify;color: rgb(255, 255, 255);\">\n<p style=\"text-align: left;text-wrap: wrap;\"><span style=\"font-size: 20px;\"><strong>\u7814\u7a76\u601d\u8def<\/strong><\/span><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;align-self: stretch;flex: 0 0 auto;min-width: 5%;height: auto;line-height: 0.1;margin-left: -10px;\">\n<section style=\"display: flex;width: 100%;flex-flow: column;\">\n<section style=\"z-index: 1;\">\n<section style=\"text-align: left;\">\n<section style=\"display: inline-block;width: 0px;height: 0px;vertical-align: top;overflow: hidden;border-style: solid;border-width: 0px 10px 44px;border-color: rgba(255, 255, 255, 0) rgba(255, 255, 255, 0) rgb(255, 205, 104);\">\n<section style=\"text-align: justify;\">\n<p style=\"text-wrap: wrap;\"><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-bottom: 0px;\"><span style=\"font-family: \u5b8b\u4f53;font-size: 16px;text-indent: 0em;letter-spacing: 0.034em;\">\u4f7f\u7528\u57fa\u4e8e\u5df2\u53d1\u8868\u7684\u5168\u57fa\u56e0\u7ec4\u5173\u8054\u7814\u7a76 \uff08GWAS\uff09 \u6c47\u603b\u7edf\u8ba1\u7684\u53cc\u6837\u672c\u5b5f\u5fb7\u5c14\u968f\u673a\u5316 \uff08MR\uff09 \u5206\u6790\u8bc4\u4f30\u4e86\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u7ec4\u6210\u4e0e\u8113\u6bd2\u75c7\u4e4b\u95f4\u7684\u5173\u8054\u3002<\/span><span style=\"font-family: \u5b8b\u4f53;font-size: 16px;text-indent: 0em;letter-spacing: 0.034em;\">\u8fdb\u884c\u4e86\u654f\u611f\u6027\u5206\u6790\u4ee5\u9a8c\u8bc1\u7ed3\u679c\u7684\u7a33\u5065\u6027\u3002<\/span><span style=\"font-family: \u5b8b\u4f53;font-size: 16px;text-indent: 0em;letter-spacing: 0.034em;\">\u5bf9GWAS\u548c\u8868\u8fbe\u6570\u91cf\u6027\u72b6\u4f4d\u70b9\uff08eQTL\uff09\u6570\u636e\u8fdb\u884c\u53cd\u5411MR\u5206\u6790\u548c\u6574\u5408\uff0c\u4ee5\u786e\u5b9a\u6f5c\u5728\u7684\u57fa\u56e0\u548c\u6cbb\u7597\u9776\u70b9\u3002<\/span><br \/><\/p>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100011490\" data-ratio=\"1.0555555555555556\" data-type=\"png\" data-w=\"612\" height=\"584.47998046875\" width=\"553.739990234375\" style=\"height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_Ha7oWBnfEaey7gaTWhppvlPIlZTmJg.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTT148UKrrdRGcOEvqFA1ZaGaI7ZibPnkuGz0VYx6Xgic4ibfwHa7oWBnfEaey7gaTWhppvlPIlZTmJg\/640?wx_fmt=png'\" \/><\/span><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 16px;\">\u56fe1\uff1a\u7814\u7a76\u6d41\u7a0b\u56fe<\/span><span style=\"text-align: justify;text-indent: 0em;letter-spacing: 0.034em;\"><\/span><\/section>\n<section style=\"font-size: 16px;margin-bottom: 0px;\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;height: auto;\">\n<section style=\"transform: perspective(0px);transform-style: flat;\">\n<section style=\"transform: rotateY(180deg);\">\n<section style=\"display: inline-block;vertical-align: top;overflow: hidden;height: 0px;width: 0px;border-style: solid;border-width: 0px 10px 44px 0px;border-color: rgba(255, 255, 255, 0) rgba(255, 255, 255, 0) rgb(71, 193, 168);\">\n<section style=\"text-align: justify;\">\n<p style=\"text-wrap: wrap;\"><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: stretch;flex: 0 0 auto;min-width: 5%;height: auto;padding: 8px 11px;background-color: rgb(71, 193, 168);\">\n<section style=\"text-align: left;transform: translate3d(-4px, 0px, 0px);\">\n<section style=\"text-align: justify;color: rgb(255, 255, 255);\">\n<p style=\"text-align: left;text-wrap: wrap;\"><span style=\"font-size: 20px;\"><strong>\u7814\u7a76\u65b9\u6cd5<\/strong><\/span><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;align-self: stretch;flex: 0 0 auto;min-width: 5%;height: auto;line-height: 0.1;margin-left: -10px;\">\n<section style=\"display: flex;width: 100%;flex-flow: column;\">\n<section style=\"z-index: 1;\">\n<section style=\"text-align: left;\">\n<section style=\"display: inline-block;width: 0px;height: 0px;vertical-align: top;overflow: hidden;border-style: solid;border-width: 0px 10px 44px;border-color: rgba(255, 255, 255, 0) rgba(255, 255, 255, 0) rgb(255, 205, 104);\">\n<section style=\"text-align: justify;\">\n<p style=\"text-wrap: wrap;\"><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-bottom: 0px;\"><span style=\"font-size: 12pt;text-indent: 0em;font-family: "Times New Roman";font-weight: bold;letter-spacing: 0.034em;font-variant-numeric: normal;font-variant-east-asian: normal;font-variant-alternates: normal;font-variant-position: normal;\">1.<\/span><span style=\"font-family: \u5b8b\u4f53;font-size: 12pt;text-indent: 0em;font-weight: bold;letter-spacing: 0.034em;font-variant-numeric: normal;font-variant-east-asian: normal;font-variant-alternates: normal;font-variant-position: normal;\">\u6570\u636e\u6e90<\/span><br \/><\/p>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u672c\u7814\u7a76\u4e2d\u4f7f\u7528\u7684<\/span><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u7684\u9057\u4f20\u6570\u636e<\/span><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u6765\u81eaMibiogen\u8054\u76df\u8fdb\u884c\u7684\u6700\u65b0\u5168\u57fa\u56e0\u7ec4\u5173\u8054\u7814\u7a76\uff08GWAS\uff09\u6c47\u603b\u6570\u636e\u3002\u8be5\u6570\u636e\u5305\u62ec\u6765\u81ea24\u4e2a\u961f\u5217\u768418,340\u540d\u53c2\u4e0e\u8005\uff0c\u5176\u4e2d85%\u662f\u6b27\u6d32\u8840\u7edf\u3002\u57fa\u4e8e16S rRNA\u57fa\u56e0\u6d4b\u5e8f\u7ed3\u679c\uff0c\u8bc4\u4f30\u4e866\u4e2a\u5c42\u6b21\u7684211\u4e2a\u5206\u7c7b\u7fa4\uff0c\u5305\u62ec9\u95e8\u300116\u7c7b\u300120\u76ee\u300135\u79d1\u548c131\u5c5e\u3002\u5bf9\u4e8e<\/span><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u4e3b\u8981\u7ed3\u5c40<\/span><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\uff0c\u4ece\u82f1\u56fd\u751f\u7269\u6837\u672c\u5e93\uff08UK Biobank\uff09\u83b7\u5f97\u4e86\u8113\u6bd2\u75c7\u6570\u636e\uff0c\u8fd9\u662f\u4e00\u9879\u9488\u5bf9\u82f1\u56fd\u6210\u5e74\u4eba\u7684\u5927\u89c4\u6a21\u4eba\u7fa4\u961f\u5217\u7814\u7a76\uff0c\u8be5\u6570\u636e\u96c6\u5305\u62ec11,643\u4f8b\u8113\u6bd2\u75c7\u75c5\u4f8b\u548c474,841\u4f8b\u6b27\u6d32\u8840\u7edf\u7684\u5bf9\u7167\u3002\u5bf9\u4e8e<\/span><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u6b21\u8981\u7ed3\u5c40<\/span><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\uff0c\u83b7\u5f97\u4e86\u8113\u6bd2\u75c7\u751f\u5b58\u6570\u636e\u3001COPD\/\u54ee\u5598\/ILD\u76f8\u5173\u80ba\u708e\u6216\u80ba\u708e\u884d\u751f\u8d25\u8840\u75c7\u3001COPD\/\u54ee\u5598\u76f8\u5173\u80ba\u708e\u6216\u80ba\u708e\u884d\u751f\u8d25\u8840\u75c7\u4ee5\u53ca\u54ee\u5598\u76f8\u5173\u80ba\u708e\u6216\u8d25\u8840\u75c7\u3002\u4e3a\u4e86\u83b7\u5f97\u66f4\u5927\u7684\u8113\u6bd2\u75c7\u751f\u5b58\u6570\u636e\u6837\u672c\uff0c\u5229\u7528\u4e86\u5148\u524d\u5173\u4e8e\u8113\u6bd2\u75c7\u751f\u5b58\u7684\u5168\u57fa\u56e0\u7ec4\u5173\u8054\u7814\u7a76\uff08GWAS\uff09\u7684\u6c47\u603b\u6570\u636e\u3002<\/span><\/span><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-weight: bold;text-indent: 0em;letter-spacing: 0.034em;\">2.MR\u5206\u6790<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 16px;\">\u91c7\u7528\u9006\u65b9\u5dee\u52a0\u6743\uff08inverse variance-weighted\uff0c IVW\uff09\u65b9\u6cd5\u4f5c\u4e3a\u4e3b\u8981\u65b9\u6cd5\uff0c\u5e76\u91c7\u7528MR Egger\u3001\u52a0\u6743\u4e2d\u4f4d\u6570\u3001\u7b80\u5355\u6a21\u5f0f\u548c\u52a0\u6743\u6a21\u5f0f\u8fdb\u884cMR\u5206\u6790\uff0c\u4ee5\u8bc4\u4f30\u80a0\u9053\u83cc\u7fa4\u5bf9\u8113\u6bd2\u75c7\u548c\u5176\u4ed6\u611f\u67d3\u76f8\u5173\u4e8b\u4ef6\u7684\u56e0\u679c\u5f71\u54cd\u3002\u91c7\u7528Wald\u6bd4\u503c\u6cd5\u4f30\u8ba1\u5404SNP\u7684\u5f71\u54cd\u3002\u5e94\u7528Cochrane\u7684Q\u68c0\u9a8c\u6765\u8bc4\u4f30SNP\u5de5\u5177\u4e4b\u95f4\u7684\u5f02\u8d28\u6027\u3002\u6240\u6709\u7edf\u8ba1\u5206\u6790\u5747\u4f7f\u7528 R\uff08\u7248\u672c 4.1.3\uff09\u8fdb\u884c\u3002IVW\u3001\u52a0\u6743\u4e2d\u4f4d\u6570\u3001\u7b80\u5355\u6a21\u6001\u3001\u52a0\u6743\u6a21\u6001\u548cMR Egger\u56de\u5f52\u65b9\u6cd5\u4f7f\u7528\u201cTwoSampleMR\u201d\u5305\uff080.5.4\u7248\uff09\u5b9e\u73b0\u3002MR-PRESSO\u6d4b\u8bd5\u662f\u4f7f\u7528\u201cMRPRESSO\u201d\u8f6f\u4ef6\u5305\u8fdb\u884c\u7684\u3002<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-weight: bold;text-indent: 0em;letter-spacing: 0.034em;font-variant-numeric: normal;font-variant-east-asian: normal;font-variant-alternates: normal;font-variant-position: normal;\">3.<\/span><span style=\"font-weight: bold;text-indent: 0em;letter-spacing: 0.034em;font-variant-numeric: normal;font-variant-east-asian: normal;font-variant-alternates: normal;font-variant-position: normal;\">\u5c06SNP\u5b9a\u4f4d\u5230\u57fa\u56e0<\/span><span style=\"font-family: "Times New Roman";font-weight: bold;text-indent: 0em;letter-spacing: 0.034em;\">    <\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 16px;\">\u5229\u7528\u5728\u7ebf\u6570\u636e\u5e93SNPnexus\uff0c\u5c06\u6bcf\u4e2a\u67e5\u8be2\u5230\u7684\u53d8\u5f02\u6620\u5c04\u5230\u5176\u6700\u63a5\u8fd1\u7684\u57fa\u56e0\uff0c\u57fa\u4e8e\u4e0a\u8ff0\u7ed3\u679c\uff0c\u6211\u4eec\u5bf9IV SNPs\u548c\u66b4\u9732\u57fa\u56e0\u8fdb\u884c\u4e86MR\u5206\u6790\u3002eQTL\u7684\u603b\u4f53\u6c34\u5e73\u7edf\u8ba1\u6765\u81eaCAGE\u7814\u7a76\u3002<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-weight: bold;text-indent: 0em;letter-spacing: 0.034em;font-variant-numeric: normal;font-variant-east-asian: normal;font-variant-alternates: normal;font-variant-position: normal;\">4.<\/span><span style=\"font-weight: bold;text-indent: 0em;letter-spacing: 0.034em;font-variant-numeric: normal;font-variant-east-asian: normal;font-variant-alternates: normal;font-variant-position: normal;\">\u5355\u7ec6\u80deRNA\u6d4b\u5e8f\u6570\u636e\u5206\u6790<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 16px;\">\u83b7\u5f97\u4e86\u8113\u6bd2\u75c7\u60a3\u8005\u7684\u5355\u7ec6\u80deRNA\u6d4b\u5e8f\uff08scRNA-seq\uff09\u6570\u636e\uff08GSE167363\uff09\uff0c\u7eb3\u5165\u4e862\u4f8b\u9769\u5170\u9634\u6027\u8113\u6bd2\u75c7\u60a3\u8005\u5065\u5eb7\u5bf9\u7167\u30014\u4f8b\u751f\u5b58\u8005\u548c6\u4f8b\u975e\u5e78\u5b58\u8005\u7684\u4eba\u5916\u5468\u8840\u5355\u6838\u7ec6\u80de\u3002<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-weight: bold;text-indent: 0em;letter-spacing: 0.034em;font-variant-numeric: normal;font-variant-east-asian: normal;font-variant-alternates: normal;font-variant-position: normal;\">5.<\/span><span style=\"font-weight: bold;text-indent: 0em;letter-spacing: 0.034em;font-variant-numeric: normal;font-variant-east-asian: normal;font-variant-alternates: normal;font-variant-position: normal;\">\u6279\u91cfRNA\u6570\u636e\u5206\u6790<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 16px;\">\u4e0b\u8f7d\u4e86\u6765\u81ea\u57fa\u56e0\u8868\u8fbe\u7efc\u5408\uff08GEO\uff09\u6570\u636e\u5e93\u7684\u6570\u636eGSE65682\uff0c\u5b83\u5305\u62ec 760 \u4efd\u8113\u6bd2\u75c7\u8840\u6db2\u6837\u672c\u548c 42 \u4efd\u5065\u5eb7\u5bf9\u7167\u8840\u6db2\u6837\u672c\uff0c\u5305\u62ec 365 \u4efd\u6765\u81ea\u5b58\u6d3b 28 \u5929\u7684\u60a3\u8005\u6837\u672c\u548c 114 \u4efd\u6765\u81ea 28 \u5929\u5185\u6b7b\u4ea1\u60a3\u8005\u7684\u6837\u672c\u3002\u6570\u636e\u662f\u4f7f\u7528GPL13667[HG-U219\u7cfb\u5217]Affymetrix \u4eba\u7c7b\u57fa\u56e0\u7ec4 U219 \u9635\u5217\u5e73\u53f0\u3002\u5728\u5bf9\u4e34\u5e8a\u4fe1\u606f\u8fdb\u884c\u6807\u51c6\u5316\u3001\u6ce8\u91ca\u548c\u6e05\u7406\u540eGSE65682\u6570\u636e\u96c6\u4e2d\uff0c\u4f7f\u7528 limma R \u5305\u6765\u9274\u5b9a\u8113\u6bd2\u75c7\u7ec4\u548c\u5065\u5eb7\u5bf9\u7167\u7ec4\u4e4b\u95f4\u7684\u5dee\u5f02\u8868\u8fbe\u57fa\u56e0 \uff08DEGs\uff09\uff0c\u4ee5\u53ca 28 \u5929\u5185\u6b7b\u4ea1\u7684\u60a3\u8005\u548c\u5b58\u6d3b 28 \u5929\u7684\u60a3\u8005\u6837\u672c\u4e4b\u95f4\u7684\u5dee\u5f02\u8868\u8fbe\u57fa\u56e0 \uff08DEGs\uff09\u3002<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-weight: bold;text-indent: 0em;letter-spacing: 0.034em;font-variant-numeric: normal;font-variant-east-asian: normal;font-variant-alternates: normal;font-variant-position: normal;\">6.<\/span><span style=\"font-weight: bold;text-indent: 0em;letter-spacing: 0.034em;font-variant-numeric: normal;font-variant-east-asian: normal;font-variant-alternates: normal;font-variant-position: normal;\">\u5206\u5b50\u5bf9\u63a5<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 16px;\">\u4ecePubChem\u6570\u636e\u5e93\u4e2d\u83b7\u5f97\u4e86\u6bcf\u79cd\u5c0f\u5206\u5b50\u914d\u4f53\u836f\u7269\u7684\u4e8c\u7ef4\u7ed3\u6784\uff0c\u9776\u86cb\u767d\uff08\u53d7\u4f53\uff09\u7684 3D \u7ed3\u6784\u662f\u4ece RCSB \u86cb\u767d\u8d28\u6570\u636e\u5e93\u83b7\u5f97\u7684\u3002\u5c06\u7ed3\u6784\u5bfc\u5165 PyMOL \u4ee5\u53bb\u9664\u6c34\u5206\u5b50\u548c\u914d\u4f53\u3002\u4f7f\u7528 AutoDock Vina\uff08\u7248\u672c 1.1.2\uff09\u8fdb\u884c\u5206\u5b50\u5bf9\u63a5\u5206\u6790\u3002\u6700\u540e\uff0c\u4f7f\u7528PyMOL\u53ef\u89c6\u5316\u6700\u4f73\u9884\u6d4b\u7ed3\u5408\u4f4d\u70b9<\/span><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><br \/><\/section>\n<section style=\"font-size: 16px;margin-bottom: 0px;\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;height: auto;\">\n<section style=\"transform: perspective(0px);transform-style: flat;\">\n<section style=\"transform: rotateY(180deg);\">\n<section style=\"display: inline-block;vertical-align: top;overflow: hidden;height: 0px;width: 0px;border-style: solid;border-width: 0px 10px 44px 0px;border-color: rgba(255, 255, 255, 0) rgba(255, 255, 255, 0) rgb(71, 193, 168);\">\n<section style=\"text-align: justify;\">\n<p style=\"text-wrap: wrap;\"><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: stretch;flex: 0 0 auto;min-width: 5%;height: auto;padding: 8px 11px;background-color: rgb(71, 193, 168);\">\n<section style=\"text-align: left;transform: translate3d(-4px, 0px, 0px);\">\n<section style=\"text-align: justify;color: rgb(255, 255, 255);\">\n<p style=\"text-align: left;text-wrap: wrap;\"><span style=\"font-size: 20px;\"><strong>\u4e3b\u8981\u7ed3\u679c<\/strong><\/span><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;align-self: stretch;flex: 0 0 auto;min-width: 5%;height: auto;line-height: 0.1;margin-left: -10px;\">\n<section style=\"display: flex;width: 100%;flex-flow: column;\">\n<section style=\"z-index: 1;\">\n<section style=\"text-align: left;\">\n<section style=\"display: inline-block;width: 0px;height: 0px;vertical-align: top;overflow: hidden;border-style: solid;border-width: 0px 10px 44px;border-color: rgba(255, 255, 255, 0) rgba(255, 255, 255, 0) rgb(255, 205, 104);\">\n<section style=\"text-align: justify;\">\n<p style=\"text-wrap: wrap;\"><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-size: 16px;font-weight: bold;text-indent: 0em;letter-spacing: 0.034em;\">1. \u5b5f\u5fb7\u5c14\u968f\u673a\u5316<\/span><br \/><\/p>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 16px;\">\u901a\u8fc7\u9006\u65b9\u5dee\u52a0\u6743\uff08IVW\uff09MR\u5206\u6790\uff0c\u786e\u5b9a\u4e86\u5bf9\u4e3b\u8981\u7ed3\u5c40\u8113\u6bd2\u75c7\u6709\u56e0\u679c\u5f71\u54cd\u768411\u4e2a\u5206\u7c7b\u7ec4\uff0c\u53d1\u73b0Lentisphaeria\u7c7b\u4e30\u5ea6\u589e\u52a0\u3001\u7caa\u7403\u83cc\u5c5e\u3001Dialiste\u5c5e\u3001\u6bdb\u87ba\u83cc\u79d1UCG004\u5c5e\u3001\u98df\u7269\u8c37\u83cc\u76ee\u3001\u9ecf\u80f6\u7403\u5f62\u83cc\u95e8\u4e0e\u8113\u6bd2\u75c7\u5448\u6b63\u76f8\u5173\uff0c\u800c\u68ad\u72b6\u82bd\u80de\u6746\u83cc\u79d11\u79d1\u3001Elogens\u5c5e\u771f\u6746\u83cc\u5c5e\u3001Gordonibacter\u5c5e\u3001\u6bdb\u87ba\u83cc\u79d1ND3007\u5c5e\u3001 \u7624\u80c3\u7403\u83cc\u79d1UCG011\u5c5e\u5177\u6709\u8d1f\u56e0\u679c\u6548\u5e94\uff08\u56fe1\uff09\u3002\u901a\u8fc7\u5f52\u4e00\u5206\u6790\uff0c\u8868\u660e\u5728\u5404\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u5bf9\u8113\u6bd2\u75c7\u548c\u5176\u4ed6\u7ed3\u5c40\u7684\u56e0\u679c\u4f30\u8ba1\u65b9\u9762\u65e0\u663e\u8457\u5dee\u5f02\uff08\u56fe2\uff09\u3002\u901a\u8fc7\u53cd\u5411MR\u5206\u6790\uff0c\u6ca1\u6709\u8bc1\u636e\u8868\u660e\u8fd9\u4e9b\u75be\u75c5\u4e0e\u80a0\u9053\u5fae\u751f\u7269\u7c7b\u7fa4\u4e4b\u95f4\u5b58\u5728\u56e0\u679c\u5173\u7cfb\u3002   <\/span><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;letter-spacing: 0.4pt;background: rgb(255, 255, 255);font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100011492\" data-ratio=\"0.6990740740740741\" data-type=\"png\" data-w=\"1080\" height=\"387.1400146484375\" width=\"553.739990234375\" style=\"height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_HoaUgEaZHQZBrrnvXf1rAT7JibQxEQ.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTT148UKrrdRGcOEvqFA1ZaibdyL5ZqRsDjcLnrg76V5QUsIibHoaUgEaZHQZBrrnvXf1rAT7JibQxEQ\/640?wx_fmt=png'\" \/><\/span><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;letter-spacing: 0.4pt;background: rgb(255, 255, 255);\">\u56fe2\uff1a\u80a0\u9053\u83cc\u7fa4\u4e0e\u8113\u6bd2\u75c7\u4e4b\u95f4\u56e0\u679c\u5173\u7cfb\u7684\u6563\u70b9\u56fe<\/span>    <\/span><o:page><\/o:page><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;letter-spacing: 0.4pt;background: rgb(255, 255, 255);font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100011491\" data-ratio=\"0.98796992481203\" data-type=\"png\" data-w=\"665\" height=\"547.0700073242188\" width=\"553.739990234375\" style=\"height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_hj2Hm2MWicwFxcX7rdH1NkxssFex2A.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTT148UKrrdRGcOEvqFA1ZajvIL5zuh5zRtZWmeH3gaspksrhj2Hm2MWicwFxcX7rdH1NkxssFex2A\/640?wx_fmt=png'\" \/><\/span><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;letter-spacing: 0.4pt;background: rgb(255, 255, 255);font-size: 16px;\">\u56fe3 \u80a0\u9053\u83cc\u7fa4\u4e0e\u8113\u6bd2\u75c7\u4e4b\u95f4\u56e0\u679c\u5173\u7cfb\u56fe<\/span><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: bold;font-size: 16px;\">2. \u57fa\u56e0\u548c\u529f\u80fd<\/span><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u901a\u8fc7\u5728\u7ebf\u6570\u636e\u5e93SNPnexus\u5c06SNP\u5b9a\u4f4d\u5230\u57fa\u56e0\uff0c\u901a\u8fc7clusterProfiler R\u8f6f\u4ef6\u5305\u5bf9\u5b9a\u4f4d\u57fa\u56e0\u8fdb\u884c\u529f\u80fd\u5bcc\u96c6\u5206\u6790\uff0cGO\u5206\u6790\u663e\u793a\uff0c\u4e0e\u75be\u75c5\u826f\u597d\u7ed3\u5c40\u76f8\u5173\u7684\u80a0\u9053\u83cc\u7fa4\u53ef\u80fd\u6d89\u53ca\u80c6\u6c41\u9178\/\u6709\u673a\u7f9f\u57fa\u5316\u5408\u7269\/\u5355\u7fa7\u9178\/\u8102\u8d28\/\u7fa7\u9178\/\u6709\u673a\u9178\u8de8\u819c\u8f6c\u8fd0\u6d3b\u6027\u7b49\u6d3b\u52a8\uff0c\u4e0e\u75be\u75c5\u4e0d\u826f\u7ed3\u5c40\u76f8\u5173\u7684\u80a0\u9053\u83cc\u7fa4\u53ef\u80fd\u6d89\u53ca\u8102\u9176\/\u6eb6\u8840\u78f7\u8102\u9176\u6d3b\u6027\u7b49\u8fc7\u7a0b\uff08\u56fe4\uff09\u3002KEGG\u901a\u8def\u5bcc\u96c6\u5206\u6790\u672a\u53d1\u73b0\u663e\u8457\u5bcc\u96c6\u901a\u8def\u3002<\/span>    <\/span><o:page><\/o:page><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100011494\" data-ratio=\"0.5022354694485842\" data-type=\"png\" data-w=\"671\" height=\"278.07000732421875\" width=\"553.739990234375\" style=\"height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_bEerpD0Qrkibib5mQ4Op4jhxy82ejA.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTT148UKrrdRGcOEvqFA1ZadNxq1kkuEyrEhMkiaswoiaXg6LmicibEerpD0Qrkibib5mQ4Op4jhxy82ejA\/640?wx_fmt=png'\" \/><\/span><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 16px;\">\u56fe4\uff1a\u4e0e\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u76f8\u5173\u7684\u6f5c\u5728\u75be\u75c5\u76f8\u5173\u5173\u952e\u57fa\u56e0\u7684\u57fa\u56e0\u672c\u4f53\u8bba\uff08GO\uff09\u672f\u8bed\u7684\u5bcc\u96c6\u5206\u6790\u56fe<\/span><\/section>\n<section style=\"text-align: justify;margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: bold;\">3.<\/span><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u5355\u7ec6\u80de\u5206\u6790\u53ca\u6279\u91cfRNA\u5206\u6790<\/span><\/span><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u5206\u6790\u4e86\u6765\u81ea12\u4e2a\u6837\u672c\u7684scRNA-seq\u6570\u636e\uff0c\u4f7f\u7528\u57fa\u4e8e\u524d15\u4e2a\u4e3b\u6210\u5206\u7684UMAP\u6280\u672f\u5bf9\u9ad8\u7ef4scRNA-seq\u6570\u636e\u8fdb\u884c\u53ef\u89c6\u5316\u3002\u968f\u540e\u5c06\u7ec6\u80de\u5206\u4e3a14\u4e2a\u5b50\u7c07\uff0c\u5e76\u4f7f\u7528SingleR R\u8f6f\u4ef6\u5305\u5c06\u5176\u6ce8\u91ca\u4e3a\u53ef\u8bc6\u522b\u7684\u7ec6\u80de\u7c7b\u578b\u3002\u4e3b\u8981\u7ec6\u80de\u7c7b\u578b\u5305\u62ecB\u7ec6\u80de\u3001\u5355\u6838\u7ec6\u80de\u3001T\u7ec6\u80de\u3001NK\u7ec6\u80de\u3001\u8840\u5c0f\u677f\u3001\u4e2d\u6027\u7c92\u7ec6\u80de\u3001GMP\u7c92\u7ec6\u80de-\u5355\u6838\u7ec6\u80de\u7956\u7ec6\u80de\u3001\u524dB\u7ec6\u80de\uff08CD34-\uff09\u548c\u9aa8\u9ad3\uff08\u56fe\u7b2c5A\u6bb5\uff09\u3002\u5206\u6790\u4e8611\u4e2a\u80a0\u9053\u83cc\u7fa4\u4e2d\u4e0e\u9057\u4f20\u53d8\u5f02\u76f8\u5173\u7684\u57fa\u56e0\uff0c\u68c0\u6d4b\u4e86\u8fd9\u4e9b\u57fa\u56e0\u5728\u7ec6\u80de\u4e2d\u7684\u8868\u8fbe\uff0c\u53d1\u73b0\u4e0e\u5065\u5eb7\u4e2a\u4f53\u76f8\u6bd4\uff0cPLCG2\u5728\u8d25\u8840\u75c7\u671f\u95f4\u5728\u514d\u75ab\u7ec6\u80de\u4e2d\u4e0a\u8c03\uff0cBCL6\u5728\u8d25\u8840\u75c7\u671f\u95f4\u524dB\u7ec6\u80de\uff08CD34-\uff09\u4e2d\u4e0a\u8c03\uff0cIGF2BP2\u5728GMP\u7ec6\u80de\u4e2d\u4e0a\u8c03\uff08\u56fe5B\u2013E\uff09\u3002\u5173\u4e8e28\u5929\u7684\u8d25\u8840\u75c7\u6b7b\u4ea1\u7387\uff0c\u89c2\u5bdf\u5230ZDHHC19\u5728\u5065\u5eb7\u4e2a\u4f53\u7684\u8840\u5c0f\u677f\u4e2d\u7684\u8868\u8fbe\u6700\u4f4e\uff0c\u572828\u5929\u7684\u8113\u6bd2\u75c7\u5e78\u5b58\u8005\u7684\u8840\u5c0f\u677f\u4e2d\u8868\u8fbe\u589e\u52a0\uff0c\u572828\u5929\u975e\u8113\u6bd2\u75c7\u751f\u8fd8\u8005\u7684\u8840\u5c0f\u677f\u4e2d\u6700\u9ad8\u3002\u6b64\u5916\uff0c\u4e0e\u6b63\u5e38\u6837\u672c\u76f8\u6bd4\uff0cSNRPN\u5728\u8d25\u8840\u75c7\u7684\u524dB\u7ec6\u80de\uff08CD34-\uff09\u548cT\u7ec6\u80de\u4e2d\u7684\u8868\u8fbe\u51cf\u5c11\uff08\u56fe6\uff09\u3002\u5bf9\u4e8e\u5176\u4ed6\u4f20\u67d3\u75c5\uff0c\u53d1\u73b0\u4e0e\u8d25\u8840\u75c7\u60a3\u8005\u76f8\u6bd4\uff0cFMN1\u5728\u5065\u5eb7\u4e2a\u4f53\u7684\u524dB\u7ec6\u80de\uff08CD34-\uff09\u548c\u5355\u6838\u7ec6\u80de\u4e2d\u7684\u8868\u8fbe\u8f83\u4f4e\uff0cMGLL\u5728\u5065\u5eb7\u4e2a\u4f53\u8840\u5c0f\u677f\u4e2d\u7684\u8868\u8fbe\u4e0e\u8d25\u8840\u75c7\u60a3\u8005\u76f8\u6bd4\u8f83\u8f83\u4f4e\uff0cAPP\u548cCE NPN\u5728\u5065\u5eb7\u4e2a\u4f53\u9884B\u7ec6\u80de\uff08CD34-\uff09\u4e2d\u7684\u8868\u8fbe\u4f4e\u4e8e\u8d25\u8840\u75c7\u60a3\u8005\u3002<\/span>    <\/span><o:page><\/o:page><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100011495\" data-ratio=\"1.3636363636363635\" data-type=\"png\" data-w=\"594\" height=\"721.3400268554688\" width=\"528.9400024414062\" style=\"height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_hz9M1wiaXosZX3MctklWm6DrmkIrNw.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTT148UKrrdRGcOEvqFA1ZaLuMeEmX2hgjOORnQaUwSCuq5Jhz9M1wiaXosZX3MctklWm6DrmkIrNw\/640?wx_fmt=png'\" \/><\/span><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;letter-spacing: 0.4pt;background: rgb(255, 255, 255);\">\u56fe5\uff1a\u8113\u6bd2\u75c7\u5355\u7ec6\u80de\u6570\u636e\u4e2d\u4e0e\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u76f8\u5173\u7684\u8113\u6bd2\u75c7\u6f5c\u5728\u5173\u952e\u57fa\u56e0\u7684\u8868\u8fbe    <\/span>    <\/span><o:page><\/o:page><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: bold;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100011497\" data-ratio=\"0.9168336673346693\" data-type=\"png\" data-w=\"998\" height=\"507.6700439453125\" width=\"553.739990234375\" style=\"height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_q7BQraszibPpYhEGGAG1ZkgHO7Eicw.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTT148UKrrdRGcOEvqFA1Zacdcmw0WnAxXssI7x9ImcNF0rcWq7BQraszibPpYhEGGAG1ZkgHO7Eicw\/640?wx_fmt=png'\" \/><\/span><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;letter-spacing: 0.4pt;background: rgb(255, 255, 255);font-size: 16px;\">\u56fe6\uff1a\u8113\u6bd2\u75c7\u5355\u7ec6\u80de\u6570\u636e\u4e2d\u4e0e\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u76f8\u5173\u7684\u8113\u6bd2\u75c7\u975e\u5e78\u5b58\u8005\u7684\u6f5c\u5728\u5173\u952e\u57fa\u56e0\u7684\u8868\u8fbe<\/span><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: bold;\">4.<\/span><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u5206\u5b50\u5bf9\u63a5<\/span><\/span><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-size: 16px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u5728\u8d25\u8840\u75c7\u4e2d\uff0c\u53d1\u73b0\u6c1f\u5c3f\u5627\u5576\u53ef\u4ee5\u964d\u4f4eNTSR1\u7684\u8868\u8fbe\u3002\u73af\u78f7\u9170\u80fa\u3001\u5730\u585e\u7c73\u677e\u3001\u963f\u9709\u7d20\u3001\u8102\u591a\u7cd6\u548c\u767d\u85dc\u82a6\u9187\u53ef\u964d\u4f4eBCL6\u7684\u8868\u8fbe\u3002\u767d\u85dc\u82a6\u9187\u53ef\u964d\u4f4eZDHHC19\u7684\u8868\u8fbe\u3002\u987a\u94c2\u3001\u5730\u585e\u7c73\u677e\u3001\u963f\u9709\u7d20\u3001\u5f02\u4e19\u80be\u4e0a\u817a\u7d20\u548c\u62d3\u6251\u66ff\u5eb7\u53ef\u964d\u4f4eMGLL\u7684\u8868\u8fbe\u3002\u963f\u9709\u7d20\u53ef\u964d\u4f4eALPK1\u548cPLCG2\u7684\u8868\u8fbe\u3002\u963f\u9709\u7d20\u3001\u5432\u54da\u7f8e\u8f9b\u3001\u892a\u9ed1\u7d20\u3001\u7532\u6c28\u8776\u5464\u548c\u767d\u85dc\u82a6\u9187\u53ef\u964d\u4f4eAPP\u7684\u8868\u8fbe\u3002\u767d\u85dc\u82a6\u9187\u548c\u957f\u6625\u65b0\u78b1\u53ef\u964d\u4f4eSNRPN\u7684\u8868\u8fbe\u3002\u5730\u585e\u7c73\u677e\u53ef\u589e\u52a0VAV2\u7684\u8868\u8fbe\u3002\u5e86\u5927\u9709\u7d20\u53ef\u589e\u52a0SATB1\u7684\u8868\u8fbe\u3002\u96cc\u4e8c\u9187\u80fd\u589e\u52a0FCHO1\u7684\u8868\u8fbe\u3002\u5e86\u5927\u9709\u7d20\u3001\u5f02\u4e19\u80be\u4e0a\u817a\u7d20\u3001\u7532\u6c28\u8776\u5464\u548c\u767d\u85dc\u82a6\u9187\u53ef\u589e\u52a0IGF2BP2\u7684\u8868\u8fbe\u3002\u5e86\u5927\u9709\u7d20\u548c\u767d\u85dc\u82a6\u9187\u53ef\u4ee5\u589e\u52a0CENPN\u7684\u8868\u8fbe\uff08\u56fe7\uff09\u3002<\/span>    <\/span><o:page><\/o:page><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;font-size: 16px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100011496\" data-ratio=\"1.0201550387596898\" data-type=\"png\" data-w=\"645\" height=\"564.8800048828125\" width=\"553.739990234375\" style=\"height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/10_ibGSoU15hbIIGqib1kNOlibE7exjBA.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LTT148UKrrdRGcOEvqFA1ZaauZLVicCCXPplaoJxeu1204okxL3ibGSoU15hbIIGqib1kNOlibE7exjBA\/640?wx_fmt=png'\" \/><\/span><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;letter-spacing: 0.4pt;background: rgb(255, 255, 255);font-size: 16px;\">\u56fe7\uff1a\u8113\u6bd2\u75c7\u6f5c\u5728\u6cbb\u7597\u9776\u70b9\u548c\u6f5c\u5728\u6cbb\u7597\u836f\u7269\u7684\u5206\u5b50\u5bf9\u63a5\u56fe<\/span><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: bold;font-size: 16px;\">          <o:p> <\/o:p><\/span><span style=\"background-color: rgb(255, 255, 255);font-family: "Times New Roman";letter-spacing: 0.4pt;text-indent: 0em;\">        <\/span><o:p style=\"font-family: "Times New Roman";letter-spacing: 0.4pt;text-indent: 0em;\"> <\/o:p><\/section>\n<section style=\"margin-left: 0pt;line-height: 120%;font-size: 12pt;font-family: \u5b8b\u4f53;font-weight: normal;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;\"><span style=\"font-family: "Times New Roman";font-variant: normal;text-transform: none;letter-spacing: 0.4pt;background: rgb(255, 255, 255);font-size: 16px;\"><o:p><\/o:p><\/span><\/section>\n<section style=\"font-size: 16px;margin-bottom: 0px;\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;height: auto;\">\n<section style=\"transform: perspective(0px);transform-style: flat;\">\n<section style=\"transform: rotateY(180deg);\">\n<section style=\"display: inline-block;vertical-align: top;overflow: hidden;height: 0px;width: 0px;border-style: solid;border-width: 0px 10px 44px 0px;border-color: rgba(255, 255, 255, 0) rgba(255, 255, 255, 0) rgb(71, 193, 168);\">\n<section style=\"text-align: justify;\">\n<p style=\"text-wrap: wrap;\"><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: stretch;flex: 0 0 auto;min-width: 5%;height: auto;padding: 8px 11px;background-color: rgb(71, 193, 168);\">\n<section style=\"text-align: left;transform: translate3d(-4px, 0px, 0px);\">\n<section style=\"text-align: justify;color: rgb(255, 255, 255);\">\n<p style=\"text-align: left;text-wrap: wrap;\"><span style=\"font-size: 20px;\"><strong>\u6587\u7ae0\u5c0f\u7ed3<\/strong><\/span><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;align-self: stretch;flex: 0 0 auto;min-width: 5%;height: auto;line-height: 0.1;margin-left: -10px;\">\n<section style=\"display: flex;width: 100%;flex-flow: column;\">\n<section style=\"z-index: 1;\">\n<section style=\"text-align: left;\">\n<section style=\"display: inline-block;width: 0px;height: 0px;vertical-align: top;overflow: hidden;border-style: solid;border-width: 0px 10px 44px;border-color: rgba(255, 255, 255, 0) rgba(255, 255, 255, 0) rgb(255, 205, 104);\">\n<section style=\"text-align: justify;\">\n<p style=\"text-wrap: wrap;\"><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-bottom: 0px;\"><span style=\"font-family: \u5b8b\u4f53;font-size: 12pt;text-indent: 0em;letter-spacing: 0.034em;font-variant-numeric: normal;font-variant-east-asian: normal;font-variant-alternates: normal;font-variant-position: normal;\">\u8be5\u7814\u7a76\u91c7\u7528MR\u8bc4\u4f30\u80a0\u9053\u83cc\u7fa4\u4e0e\u8113\u6bd2\u75c7\u4e4b\u95f4\u7684\u56e0\u679c\u5173\u7cfb\uff0c\u6574\u5408\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u5b66\u548c\u6279\u91cfRNA\u6d4b\u5e8f\u6280\u672f\u5168\u9762\u9610\u660e\u80a0\u9053\u83cc\u7fa4\u5728\u8113\u6bd2\u75c7\u53d1\u5c55\u4e2d\u7684\u6f5c\u5728\u673a\u5236\uff0c\u901a\u8fc7\u7ed3\u5408\u80a0\u9053\u83cc\u7fa4\u7684\u8c03\u63a7\u673a\u5236\u548c\u73b0\u6709\u7684\u836f\u7269\u6570\u636e\u5e93\uff0c\u8bc6\u522b\u6f5c\u5728\u7684\u6cbb\u7597\u836f\u7269\u5e76\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u5176\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\uff0c\u4e3a\u8113\u6bd2\u75c7\u4e2a\u4f53\u5316\u6cbb\u7597\u7b56\u7565\u7684\u5236\u5b9a\u63d0\u4f9b\u4e86\u601d\u8def\uff0c\u4e3a\u672a\u6765\u7684\u836f\u7269\u5f00\u53d1\u63d0\u4f9b\u4e86\u521d\u6b65\u7684\u5019\u9009\u9776\u70b9\u548c\u836f\u7269\u3002<\/span><span style=\"font-family: \u5b8b\u4f53;font-size: 12pt;text-indent: 0em;letter-spacing: 0.034em;font-variant-numeric: normal;font-variant-east-asian: normal;font-variant-alternates: normal;font-variant-position: normal;color: rgb(255, 0, 0);font-weight: bold;background: rgb(255, 255, 0);\">\u5b5f\u5fb7\u5c14\u968f\u673a\u5316+\u5355\u7ec6\u80de+\u7f51\u7edc\u836f\u7406\u5b66+\u5206\u5b50\u5bf9\u63a5\u5f3a\u5f3a\u8054\u5408\u7a33\u7a33\u62ff\u4e0b7\u5206+SCI\uff01\u611f\u5174\u8da3\u7684\u670b\u53cb\u4eec\uff0c\u5feb\u6293\u7d27\u65f6\u95f4\u884c\u52a8\u8d77\u6765\uff01<\/span><span style=\"font-family: \u5b8b\u4f53;font-size: 12pt;text-indent: 0em;letter-spacing: 0.034em;\">  <\/span><\/p>\n<p style=\"text-indent: 0px;margin-bottom: 0px;\"><span style=\"color: rgb(0, 122, 170);\"><strong><span style=\"color: rgb(0, 122, 170);letter-spacing: 0.578px;text-indent: 32px;text-wrap: wrap;background-color: rgb(255, 255, 255);font-size: 15px;\">\u5c0f\u679c\u8fd8<span style=\"color: rgb(0, 122, 170);background-color: rgb(255, 255, 255);font-size: 15px;letter-spacing: 0.578px;text-decoration: none solid rgba(0, 0, 0, 0.9);\">\u63d0\u4f9b\u601d\u8def\u8bbe\u8ba1\u3001\u5b9a\u5236\u751f\u4fe1\u5206\u6790\u3001\u6587\u732e\u601d\u8def\u590d\u73b0\uff1b\u6709\u9700\u8981\u7684\u5c0f\u4f19\u4f34\u6b22\u8fce\u76f4\u63a5\u626b\u7801\u54a8\u8be2\u5c0f\u679c\uff0c\u7aed\u8bda\u4e3a\u60a8\u7684\u79d1\u7814\u52a9\u529b\uff01<\/span><\/span><\/strong><\/span><\/p>\n<p style=\"margin-bottom: 0px;\"><br \/><\/p>\n<section style=\"font-size: 15px;padding-right: 2px;padding-left: 2px;margin-bottom: 0px;\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;flex: 0 0 auto;height: auto;border-color: rgb(114, 114, 114);border-width: 1px;border-style: solid;box-shadow: rgb(194, 209, 255) -5px 5px 0px;align-self: flex-start;\">\n<section style=\"justify-content: center;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 42.6829%;vertical-align: middle;box-shadow: rgb(43, 65, 110) 0px 0px 0px;flex: 0 0 auto;height: auto;padding-left: 10px;align-self: center;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;line-height: 0;transform: translate3d(20px, 0px, 0px);\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;width: 75%;height: auto;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-imgfileid=\"100018517\" data-ratio=\"1\" data-s=\"300,640\" data-type=\"jpeg\" data-w=\"430\" style=\"vertical-align: middle;width: 100%;height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_B2jkicacLzPjw4xMSqVvoucZjonVDA-47.jpg\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAxVYfSsM0wdf9d3RpNiaTcHohxPNEVs2VFhPMukpU8lchxrvcB2jkicacLzPjw4xMSqVvoucZjonVDA\/640?wx_fmt=jpeg'&from=appmsg\" \/><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: 56.9106%;flex: 0 0 auto;height: auto;align-self: center;\">\n<section style=\"line-height: 2;letter-spacing: 1px;color: rgb(43, 65, 110);\" powered-by=\"xiumi.us\">\n<p style=\"margin-bottom: 2px;\"><strong>\u5b9a\u5236\u751f\u4fe1\u5206\u6790<\/strong><\/p>\n<p style=\"margin-bottom: 2px;\"><strong>\u670d\u52a1\u5668\u79df\u8d41<\/strong><\/p>\n<p><strong>\u626b\u7801\u54a8\u8be2\u5c0f\u679c<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247497780&idx=2&sn=7eee90af6f387e4153bba13028e545a1&chksm=cf7f68f1f808e1e7dfb3a0597ef442e5c6e700ecf6ee5a035c766a4c7486c12eabd0ab218ea6&scene=21#wechat_redirect\" textvalue=\"\u4f60\u5df2\u9009\u4e2d\u4e86\u6dfb\u52a0\u94fe\u63a5\u7684\u5185\u5bb9\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"1\" rel=\"noopener\"><span class=\"js_jump_icon h5_image_link\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-imgfileid=\"100018519\" data-ratio=\"0.3253333333333333\" data-s=\"300,640\" data-type=\"png\" data-w=\"750\" style=\"vertical-align: middle;width: 100%;height: auto !important;\" src=\"http:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/12_7TvAyUibd1TPhJmZfialJtv6tu2SEg-3.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAxVYfSsM0wdf9d3RpNiaTcHoj9xlsoyiaBvzaezDUFAicibMAF8ts7TvAyUibd1TPhJmZfialJtv6tu2SEg\/640?wx_fmt=png&from=appmsg'\" \/><\/span><\/a><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\"><br \/><\/section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;text-align: left;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-end;padding-right: 2px;padding-left: 2px;\">\n<section style=\"margin: 10px 0% 2px;transform: translate3d(2px, 0px, 0px);\" powered-by=\"xiumi.us\">\n<section style=\"font-size: 16px;color: rgb(58, 66, 94);line-height: 1;letter-spacing: 5px;text-align: center;\">\n<p><strong>\u5f80\u671f\u56de\u987e<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"height: 3px;background-color: rgb(95, 156, 239);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<section style=\"margin-top: 2px;margin-right: 0%;margin-left: 0%;text-align: center;line-height: 0.8;font-size: 9px;\" powered-by=\"xiumi.us\">\n<section style=\"width: 0px;display: inline-block;border-top: 0.8em solid rgb(58, 66, 94);border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;flex: 100 100 0%;align-self: flex-end;height: auto;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"height: 3px;background-color: rgb(95, 156, 239);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<section style=\"margin-top: 2px;margin-right: 0%;margin-left: 0%;text-align: center;line-height: 0.8;font-size: 9px;\" powered-by=\"xiumi.us\">\n<section style=\"width: 0px;display: inline-block;border-top: 0.8em solid rgba(255, 255, 255, 0);border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"min-height: 40px;margin: 10px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"width: 100%;margin-right: auto;margin-bottom: -10px;margin-left: auto;\">\n<table width=\"100%\">\n<tbody>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:0\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:0.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>01<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247497780&idx=2&sn=7eee90af6f387e4153bba13028e545a1&chksm=cf7f68f1f808e1e7dfb3a0597ef442e5c6e700ecf6ee5a035c766a4c7486c12eabd0ab218ea6&scene=21#wechat_redirect\" textvalue=\"1024G\u5b58\u50a8\u7684\u751f\u4fe1\u670d\u52a1\u5668\uff0c\u4e24\u4eba\u6210\u56e2\uff0c1\u4eba\u514d\u5355\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">1024G\u5b58\u50a8\u7684\u751f\u4fe1\u670d\u52a1\u5668\uff0c\u4e24\u4eba\u6210\u56e2\uff0c1\u4eba\u514d\u5355\uff01<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:1\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:1.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>02<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247498878&idx=1&sn=fc34ed3f1d15d060bbaf8166adcebd58&chksm=cf7f6cbbf808e5ad0b5417e50ed75cfbd1b3a83ac43b97f1dfa718c822878a9a004990075133&scene=21#wechat_redirect\" textvalue=\"\u5355\u4e2a\u6570\u636e\u5e93\u7528\u817b\u4e86\uff1f\u591a\u6570\u636e\u5e93\u201c\u7ec4\u5408\u62f3\u201d\u5e26\u4f60\u6253\u5f00\u514d\u75ab\u6d78\u6da6\u65b0\u601d\u8def\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u5355\u4e2a\u6570\u636e\u5e93\u7528\u817b\u4e86\uff1f\u591a\u6570\u636e\u5e93\u201c\u7ec4\u5408\u62f3\u201d\u5e26\u4f60\u6253\u5f00\u514d\u75ab\u6d78\u6da6\u65b0\u601d\u8def\uff01<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:2\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:2.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>03<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247498673&idx=1&sn=1e09b74a836c1e64a62ae1f66eeb3f93&chksm=cf7f6b74f808e262de70be43fd73bf5fefdc0914e525eb2032f741a0152e619689cedc76946f&scene=21#wechat_redirect\" textvalue=\"\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u7684\u51c6\u5907\u5de5\u4f5c\uff0cGWAS\u6570\u636e\u7684\u7f51\u7ad9\u4e0b\u8f7d\u65b9\u6cd5\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"11\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u7684\u51c6\u5907\u5de5\u4f5c\uff0cGWAS\u6570\u636e\u7684\u7f51\u7ad9\u4e0b\u8f7d\u65b9\u6cd5<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:3\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:3.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>04<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247498517&idx=1&sn=fa3c0104cee316982fe8162b79fe234f&chksm=cf7f6bd0f808e2c6cf979704bf883cfb5480444604f90da61dc286e7541fa5bb49df0a2fb58a&scene=21#wechat_redirect\" textvalue=\"\u8ddf\u7740\u5c0f\u679c\u5b66\u590d\u73b0-\u624b\u628a\u624b\u5e26\u4f60\u62ff\u4e0bIF=46.9Nature \u7ea7\u522b\u7684\u4e3b\u6210\u5206\u5206\u6790\uff08PCA\uff09\u56fe\uff01\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u8ddf\u7740\u5c0f\u679c\u5b66\u590d\u73b0-\u624b\u628a\u624b\u5e26\u4f60\u62ff\u4e0bIF=46.9Nature \u7ea7\u522b\u7684\u4e3b\u6210\u5206\u5206\u6790\uff08PCA\uff09\u56fe\uff01\uff01<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;margin-bottom: 0px;\"><br \/><\/p>\n<p style=\"margin-bottom: 0px;\"><br \/><\/p>\n<p style=\"display: none;\"><mp-style-type data-value=\"3\"><\/mp-style-type><\/p>\n<p><\/content>\n<\/div>\n<p><\/body><br \/>\n<\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7a81\u7834\u60f3\u8c61\uff0c\u8be5\u6709\u7684\u70ed\u70b9\u4e00\u4e2a\u4e0d\u843d\u4e0b\uff01\u8d35\u5dde\u7701\u4eba\u6c11\u533b\u9662\u56e2\u961f7\u5206+\uff1a\u5b5f\u5fb7\u5c14\u968f\u673a\u5316+\u7f51\u7edc\u836f\u7406\u5b66+\u83cc\u7fa4+\u5355\u7ec6\u80de+\u5206\u5b50\u5bf9\u63a5\uff0c\u4eba […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/56708"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=56708"}],"version-history":[{"count":1,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/56708\/revisions"}],"predecessor-version":[{"id":56720,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/56708\/revisions\/56720"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=56708"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=56708"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=56708"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}