<\/title><br \/>\n<meta charset=\"utf-8\"><br \/>\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,maximum-scale=1.0,user-scalable=0,viewport-fit=cover\"><\/p>\n<style>\n*{margin:0;padding:0}html{-ms-text-size-adjust:100%;-webkit-text-size-adjust:100%;line-height:1.6}img{z-index:999;position:relative;max-width:100%;margin:10px 0;}body{letter-spacing:.034em}h1,h2,h3,h4,h5,h6{font-weight:400;font-size:16px}a{color:#576b95;text-decoration:none;-webkit-tap-highlight-color:rgba(0,0,0,0)}td,th{word-wrap:break-word;padding:5px 10px;border:1px solid #DDD;}table{margin-bottom:10px;border-collapse:collapse;display:table;width:100%!important;}.appmsg_skin_default .rich_media_area_primary{background-color:#fff}.appmsg_skin_default .rich_media_area_primary .weui-loadmore_line .weui-loadmore__tips{background-color:#fff}.rich_media_area_primary{padding:20px 16px 12px;background-color:#fafafa}@media (max-width:375px){.rich_media_area_primary{padding:20px 60px 15px 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#33ab01;margin-right:5px;}.ad{text-decoration:none;color:#d6d4d4;font-size:12px;}.msgBodyReply{padding-top:5px;}.userName span{float:right;color:#afafaf;font-size:14px;}code{text-align:left;font-size:14px;display:block;white-space:pre;display:-webkit-box;display:-webkit-flex;display:flex;position:relative;}.code-snippet__fix{font-size:14px;margin:10px 0;display:block;color:#333;position:relative;background-color:rgba(0,0,0,0.03);border:1px solid #f0f0f0;border-radius:2px;display:-webkit-box;display:-webkit-flex;display:flex;padding-left:25px;line-height:26px}.code-snippet__fix code{text-align:left;font-size:14px;display:block;white-space:pre;display:-webkit-box;display:-webkit-flex;display:flex;position:relative;font-family:Consolas,\"Liberation 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0;align-items:center}.flex_bd{padding-left:14px;}.account_nickname{display:inline-block;vertical-align:middle;line-height:1.2;color:#576b95;font-size:14px}.account_desc{overflow:hidden;text-overflow:ellipsis;display:-webkit-box;-webkit-box-orient:vertical;-webkit-line-clamp:1;color:rgba(0,0,0,0.3);font-size:14px;line-height:1.2;padding-top:.4em}.msg_source_url{text-align:left;word-break:break-all;margin-top:20px;}.msg_source_url a{padding-right:10px;}.msg_source_url .url_text{color:#a8a8a8;}.video-desc{font-size:14px;margin-top:15px;color:#6c6c6c;}.msg_source_url{text-align:left;}.original_primary_card_tips{color:rgba(0,0,0,0.3);line-height:1.4;font-size:15px;}.weui-flex__item{margin-bottom:20px;padding:20px 16px;margin-top:16px;line-height:1.4;align-items:center;background-color:#f7f7f7;border-radius:8px;position:relative;}.original_primary_desc{color:rgba(0,0,0,0.5);font-size:14px;padding-top:4px;width:auto;overflow:hidden;text-overflow:ellipsis;}.msgBodyReplyList{border-top:1px solid #e1e1e1;margin-top:10px;}.msgBodyReplyListTop{border-top:0;}.reply_like_num{float:right;font-size:14px;color:#c7c7c7;}.msgData{margin-top:20px;color:#626262;}.msgData span{font-size:14px;padding-right:15px;}.msgData .likes{float:right;padding-right:0;}.js_text_content p{font-size:18px;}.rich_media_meta_link{font-size:15px;}blockquote {padding-left: 10px;border-left: 3px solid #dbdbdb;color: rgba(0,0,0,0.5);font-size: 15px;padding-top: 4px;margin: 1em 0;}.video_iframe{width:500px;height:400px;}.blockquote_info{color:#b5b5b5;margin-top:10px;}#copyright_logo{color:#bdbdbd;}.rich_media_meta_list{margin-bottom:10px;}.reprint{background:#efefef;border-radius:5px;padding:8px;color:#1f1f1f;}.reprint a{word-break:break-all;}.topic{color:#8e8e8e;background:#f7f7f7;border-radius:5px;padding:10px 8px;}.topic a{padding-right:5px;}.topic p{margin-bottom:5px;}\n<\/style>\n<link href=\"https:\/\/www.juyifx.cn\/config\/css\/wxArticle.css\" rel=\"stylesheet\"\/>\n<\/head><script>\nvar 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id=\"js_name\">\u751f\u4fe1\u679c <\/a><\/span><em id=\"publish_time\" class=\"rich_media_meta rich_media_meta_text\">2023-09-23 19:02:26<\/em><\/div>\n<p><content><\/p>\n<div class=\"reprint\">\n<p>\u8f6c\u81ea\u516c\u4f17\u53f7\uff1a\u751f\u4fe1\u56fe<br \/><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247485247&idx=1&sn=e8c6025d2d7c6ceef691e86fddf37e47\" target=\"_blank\" title=\"\u9605\u8bfb\u539f\u6587\" rel=\"noopener\">http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247485247&idx=1&sn=e8c6025d2d7c6ceef691e86fddf37e47<\/a><\/p>\n<\/div>\n<section style=\"font-size: 16px;margin-bottom: 24px;\" data-mpa-powered-by=\"yiban.io\">\n<section style=\"display: flex;flex-flow: row;margin: 10px 0%;text-align: left;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: bottom;width: 50%;background-color: rgb(242, 183, 183);margin-right: 3px;flex: 0 0 auto;align-self: flex-end;height: auto;padding: 3px 10px;\">\n<section style=\"font-size: 17px;color: rgb(255, 255, 255);text-align: right;letter-spacing: 4px;\" powered-by=\"xiumi.us\">\n<p><strong>\u70b9\u51fb\u84dd\u5b57<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;border-left: 4px solid rgb(242, 183, 183);border-bottom-left-radius: 0px;flex: 100 100 0%;align-self: stretch;height: auto;padding: 3px 10px;background-color: rgba(254, 245, 240, 0.8);\">\n<section style=\"color: rgb(181, 126, 121);font-size: 17px;letter-spacing: 4px;\" powered-by=\"xiumi.us\">\n<p><strong>\u5173\u6ce8\u5c0f\u56fe<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 0em;white-space: normal;\">Bedtools:\u4e00\u4e2a\u5f3a\u5927\u7684\u57fa\u56e0\u7ec4\u7b97\u6cd5\u5de5\u5177\u96c6\uff0c\u7531\u72b9\u4ed6\u5927\u5b66\u6606\u5170\u5b9e\u9a8c\u5ba4\u5f00\u53d1\u7684\u3002\u603b\u7684\u6765\u8bf4\uff0cBedtools\u5de5\u5177\u662f\u4e00\u4e2a\u582a\u79f0\u745e\u58eb\u519b\u5200\u7684\u5de5\u5177\uff0c\u7528\u4e8e\u5e7f\u6cdb\u7684\u57fa\u56e0\u7ec4\u5b66\u5206\u6790\u4efb\u52a1\u3002\u6700\u5e7f\u6cdb\u4f7f\u7528\u7684\u5de5\u5177\u4f7f\u57fa\u56e0\u7ec4\u8fd0\u7b97\u6210\u4e3a\u53ef\u80fd:\u5373\u57fa\u56e0\u7ec4\u7684\u96c6\u5408\u8bba\u3002\u4f8b\u5982\uff0cbedtools\u5141\u8bb8\u4eba\u4eec\u4ece\u5e7f\u6cdb\u4f7f\u7528\u7684\u57fa\u56e0\u7ec4\u6587\u4ef6\u683c\u5f0f\uff08\u5982BAM\u3001BED\u3001GFF\/GTF\u3001VCF\uff09\u7684\u591a\u4e2a\u6587\u4ef6\u4e2d\u4ea4\u53c9\u3001\u5408\u5e76\u3001\u8ba1\u6570\u3001\u8865\u5145\u548c\u6d17\u6362\u57fa\u56e0\u7ec4\u95f4\u9694\u3002\u867d\u7136\u6bcf\u4e2a\u5355\u72ec\u7684\u5de5\u5177\u90fd\u88ab\u8bbe\u8ba1\u4e3a\u6267\u884c\u76f8\u5bf9\u7b80\u5355\u7684\u4efb\u52a1\uff08\u4f8b\u5982\uff0c\u76f8\u4ea4\u4e24\u4e2a\u95f4\u9694\u6587\u4ef6\uff09\uff0c\u4f46\u662f\u53ef\u4ee5\u6267\u884c\u76f8\u5f53\u590d\u6742\u7684\u5206\u6790\u5de5\u4f5c\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u5c0f\u56fe\u4eca\u5929\u7ed9\u5927\u5bb6\u4ecb\u7ecd\u4e24\u79cdBedtools\u5b89\u88c5\u65b9\u6cd5<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K06A9sD59ueQvpZPQauQJWUWUibUUobtCHFlJgpIicJFk8dTb3ajwqOeibA\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>\u7b2c\u4e00\u79cd<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0uuAWvdFASmFcD4MPCRn5Wpib8MIlhvrSJgem2VGvnAWaSvFs35IictNg\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">wget https:<span class=\"code-snippet__comment\">\/\/github.com\/arq5x\/bedtools2\/archive\/v2.25.0.tar.gz<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">tar xzvf v2<span class=\"code-snippet__number\">.25<\/span><span class=\"code-snippet__number\">.0<\/span> <\/span><\/code><code><span class=\"code-snippet_outer\">cd bedtools2<span class=\"code-snippet__number\">-2.25<\/span><span class=\"code-snippet__number\">.0<\/span>\/<\/span><\/code><code><span class=\"code-snippet_outer\">make<\/span><\/code><code><span class=\"code-snippet_outer\">cd bin\/<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u6dfb\u52a0\u73af\u5883\u5373\u53ef<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">export<\/span> PATH=$PWD:$PATH<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K06A9sD59ueQvpZPQauQJWUWUibUUobtCHFlJgpIicJFk8dTb3ajwqOeibA\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>\u7b2c\u4e8c\u79cd<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0uuAWvdFASmFcD4MPCRn5Wpib8MIlhvrSJgem2VGvnAWaSvFs35IictNg\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u4f7f\u7528conda\u5b89\u88c5<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u521b\u5efa\u81ea\u5df1\u7684\u73af\u5883<\/span><\/code><code><span class=\"code-snippet_outer\">source activate mypy <\/span><\/code><code><span class=\"code-snippet_outer\">#\u8fdb\u5165\u81ea\u5df1\u7684\u73af\u5883<\/span><\/code><code><span class=\"code-snippet_outer\"> conda install -c bioconda bedtools<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u4e24\u79cd\u65b9\u6cd5\u6839\u636e\u81ea\u5df1\u5b9e\u9645\u60c5\u51b5\u9009\u62e9<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u9996\u5148\uff0c\u5148\u7528\u793a\u4f8b\u6570\u636e\u4e86\u89e3\u4e00\u4e0b\u5982\u4f55\u53d6\u6570\u636e\u96c6\u4e4b\u95f4\u7684\u4ea4\u96c6\u57fa\u56e0<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.3734015345268542\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_CmNRURFqCqtaNFaAWoSRRUqaric25w.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0krk9d0AfLqwwNJ29lVSxRE7gTCmNRURFqCqtaNFaAWoSRRUqaric25w\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"782\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u4ea4\u96c6 -intersect<\/p>\n<p style=\"white-space: normal;\">gene1.ped\u5185\u5bb9\u4e3a<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.23197492163009403\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-09-23_\u300c\u8f6c\u300dGWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01\/2_tSl9r0QjURic7yQgZanu7Csuhzd9mQ.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K04iaabWprk7aWZD3dbZtJs0LbXFtSl9r0QjURic7yQgZanu7Csuhzd9mQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"319\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">gene2.ped\u5185\u5bb9\u4e3a<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.4105263157894737\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-09-23_\u300c\u8f6c\u300dGWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01\/3_R4EpZYibzibajx3Za7VbHocSKlmpcg.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0ypaaRYyXPtIyAPFWjlzw1btianmR4EpZYibzibajx3Za7VbHocSKlmpcg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"285\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c1\u5217\uff1a\u67d3\u8272\u4f53<\/p>\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c2\u5217\uff1a\u8d77\u59cb\u4f4d\u7f6e<\/p>\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c3\u5217\uff1a\u7ec8\u6b62\u4f4d\u7f6e<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u547d\u4ee4\uff1a<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">bedtools intersect -a gene1.ped -gene2.ped<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u7ed3\u679c\u5982\u4e0b\uff1a<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.4177215189873418\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_EVialPmNuHdyIoRfRbEWksQQSOzorw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0fzia3pzVLPqs8TtsWic1JN9ribdqEVialPmNuHdyIoRfRbEWksQQSOzorw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"158\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u53ef\u89c1\u56db\u4e2a\u91cd\u590d\u533a\u57df<\/p>\n<p style=\"white-space: normal;\">\u7b2c\u4e00\u4e2a\u91cd\u590d\u533a\u57df\u662f10-14<\/p>\n<p style=\"white-space: normal;\">\u7b2c\u4e8c\u4e2a\u91cd\u590d\u533a\u57df\u662f17-19<\/p>\n<p style=\"white-space: normal;\">\u7b2c\u4e09\u4e2a\u91cd\u590d\u533a\u57df\u662f80-82<\/p>\n<p style=\"white-space: normal;\">\u7b2c\u56db\u4e2a\u91cd\u590d\u533a\u57df\u662f88-90<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u5982\u679c\u60f3\u8f93\u51fa\u8ba1\u7b97A\u4e2d\u6709B\u7684\u4ea4\u96c6\u533a\u95f4\uff0c\u540c\u65f6\u8fd4\u56deA\u4e2d\u7684\u7ed3\u679c\uff1a<\/strong><\/p>\n<p style=\"white-space: normal;\"><strong>\u53ef\u52a0 -wa \u53c2\u6570<\/strong><\/p>\n<p style=\"white-space: normal;\"><strong>\u547d\u4ee4\uff1a<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">bedtools intersect -a gene1.ped -gene2.ped -wa<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u7ed3\u679c\u5982\u4e0b\uff1a<br \/><\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.42567567567567566\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_8VJq6mBciafMxaWZYEd1bMWBRYN9kA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0npozv3vxp1uR55NtQCtCZN2Uib8VJq6mBciafMxaWZYEd1bMWBRYN9kA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"148\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u5982\u679c\u60f3\u8f93\u51fa\u8ba1\u7b97A\u4e2d\u6709B\u7684\u4ea4\u96c6\u533a\u95f4\uff0c\u540c\u65f6\u8fd4\u56deB\u4e2d\u7684\u7ed3\u679c\uff1a<\/strong><\/p>\n<p style=\"white-space: normal;\"><strong>\u53ef\u52a0 -wb \u53c2\u6570<\/strong><\/p>\n<p style=\"white-space: normal;\"><strong>\u547d\u4ee4\uff1a <\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">bedtools intersect -a gene1.ped -gene2.ped -wb<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u7ed3\u679c\u5982\u4e0b\uff1a<br \/><\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.2\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-09-23_\u300c\u8f6c\u300dGWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01\/6_LSjiaIepQlcfP46TeJ74ERpxGB0Zpw.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0dEkPTF772VWObL5DKicjRB0WJSLSjiaIepQlcfP46TeJ74ERpxGB0Zpw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"325\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u4ece\u7ed3\u679c\u53ef\u89c1\uff0c\u52a0\u4e0a-wb\u53c2\u6570\u540e\uff0c\u9664\u4e86\u8f93\u51faA\u4e2d\u7684\u4ea4\u96c6\u533a\u57df\u5916\uff0c\u8fd8\u4f1a\u8f93\u51faB\u4e2d\u7684\u6574\u4e2a\u533a\u95f4\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u5982\u679c\u52a0\u4e0a-wa -wb\u53c2\u6570<\/strong><\/p>\n<p style=\"white-space: normal;\"><strong>\u547d\u4ee4\uff1a<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">bedtools intersect -a gene1.ped -gene2.ped -wa -wb<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.2168284789644013\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_9V9Baibf6YYyEtBRPxHnrOqzibe6EQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0iadw487QFB2niawebuoBCicf43XzY9V9Baibf6YYyEtBRPxHnrOqzibe6EQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"309\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">-c\u53c2\u6570\uff0c\u7edf\u8ba1A\u4e2d\u6bcf\u4e2a\u533a\u57df\u4e0eB\u91cd\u53e0\u7684\u6b21\u6570<\/p>\n<p style=\"white-space: normal;\">\u547d\u4ee4\uff1abedtools intersect -a gene1.ped -gene2.ped -c<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.2620320855614973\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-09-23_\u300c\u8f6c\u300dGWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01\/8_jibFulVRIS5sO7HfywE3e9CvVzqXnQ.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0KCWwYw5HNNHjQJF213BbZkj3ejibFulVRIS5sO7HfywE3e9CvVzqXnQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"187\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u7531\u7ed3\u679c\u53ef\u770b\u51fa\uff0c\u5728A\u6587\u4ef6\u4e2d\u67d3\u8272\u4f53\u4f4d\u7f6e\u548c\u6709\u591a\u5c11B\u6587\u4ef6\u67d3\u8272\u4f53\u4f4d\u7f6e\u4e0e\u5176\u6709\u91cd\u53e0\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 0em;white-space: normal;\">\u90a3\u4e48\uff0cGWAS\u5206\u6790\u5982\u4f55\u8fdb\u884csnp\u5982\u4f55\u505a\u6ce8\u91ca\uff0cGWAS\u5206\u6790\u4e2d\uff0c\u6211\u4eec\u7528\u57fa\u56e0\u578b\u6570\u636e\uff08SNP\uff09+\u8868\u578b\u6570\u636e\uff0c\u8fdb\u884c\u5173\u8054\u5206\u6790\uff0c\u5f97\u5230\u663e\u8457\u6027\u7684SNP\uff0c\u8fd9\u4e9bSNP\u6709\u67d3\u8272\u4f53\u548c\u7269\u7406\u4f4d\u7f6e\uff0c\u90a3\u4e48\u6211\u4eec\u5982\u4f55\u5bf9SNP\u8fdb\u884c\u57fa\u56e0\u6ce8\u91ca\u5462\uff1f\u6211\u4eec\u5982\u4f55\u5f97\u5230\u663e\u8457SNP\u9644\u8fd1\u7684\u57fa\u56e0\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u4ea4\u96c6 -intersect<\/p>\n<p style=\"white-space: normal;\">gene.ped\u5185\u5bb9\u4e3a<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.34309623430962344\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_3bcnxqRNgoSb7TNG8CZMsHjWAlib9w.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0dHC6oVnwYf30z7o8hFJ8IIibMt3bcnxqRNgoSb7TNG8CZMsHjWAlib9w\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"478\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c1\u5217\uff1a\u67d3\u8272\u4f53<\/p>\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c2\u5217\uff1a\u8d77\u59cb\u4f4d\u7f6e<\/p>\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c3\u5217\uff1a\u7ec8\u6b62\u4f4d\u7f6e<\/p>\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c4\u5217\uff1a\u7ec8\u6b62\u4f4d\u7f6e<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">snp.ped\u5185\u5bb9\u4e3a<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.5192878338278932\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-09-23_\u300c\u8f6c\u300dGWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01\/10_VCPgLIHkTT8Bu9aHGpGk73IcFVQQjg.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0iaYozVS7ibyFJEq9OnLyqG5NhQVCPgLIHkTT8Bu9aHGpGk73IcFVQQjg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"337\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c1\u5217\uff1a\u67d3\u8272\u4f53<\/p>\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c2\u5217\uff1a\u8d77\u59cb\u4f4d\u7f6e<\/p>\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c3\u5217\uff1a\u7ec8\u6b62\u4f4d\u7f6e<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u547d\u4ee4\uff1a<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">bedtools intersect -a snp.ped -b gene.ped -loj<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">intersect\uff0c\u4ea4\u96c6<br \/><\/p>\n<p style=\"white-space: normal;\">-a\uff0c\u7b2c\u4e00\u4e2a\u4f4d\u7f6e\u4fe1\u606f\u8868<\/p>\n<p style=\"white-space: normal;\">-b\uff0c\u7b2c\u4e8c\u4e2a\u4f4d\u7f6e\u4fe1\u606f\u8868<\/p>\n<p style=\"white-space: normal;\">-loj\uff0c\u4ee5\u7b2c\u4e00\u4e2a\u4e3a\u57fa\u51c6\uff0c\u8fd4\u56de\u7ed3\u679c<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.3112745098039216\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-09-23_\u300c\u8f6c\u300dGWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01\/11_5hauCNpQCSIR8akhY7h1J6f37yUYNg.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0Qb2LM68LzjI8CL0TpRc5lkPn5hauCNpQCSIR8akhY7h1J6f37yUYNg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"408\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u7ed3\u679c\u53ef\u4ee5\u770b\u5230\uff0c\u7b2c\u4e8c\u4e2aSNP\u533a\u95f4\uff0c\u5bf9\u5e94\u4e24\u4e2a\u57fa\u56e0\uff0c\u5199\u6210\u4e86\u4e24\u884c\u3002\u7b2c\u4e09\u4e2aSNP\u533a\u95f4\u6ca1\u6709\u5bf9<\/p>\n<p style=\"white-space: normal;\">\u5e94\u57fa\u56e0\uff0c\u7528-1\u8868\u793a\u5360\u4f4d\u3002\u5171\u8fd4\u56de8\u884c\u4fe1\u606f\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\"><span style=\"color: rgb(225, 109, 109);\"><strong>\u6ce8\u610f\uff1a<\/strong><\/span>\u6bcf\u4e2aSNP\u4e00\u884c\uff0c\u5982\u679c\u6709\u57fa\u56e0\u5728\u5176\u533a\u95f4\uff0c\u653e\u5230\u53f3\u8fb9\uff0c\u5982\u679c\u6ca1\u6709\u57fa\u56e0\uff0c\u8fd4\u56de\u7a7a\u3002\u5982\u679c\u4e00\u4e2aSNP\u533a\u95f4\u5bf9\u5e94\u591a\u4e2a\u57fa\u56e0\uff0c\u5199\u6210\u591a\u884c\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u5982\u679c\u4e0d\u60f3\u8981\u8fd4\u56de\u7a7a\u503c\uff0c\u53ea\u60f3\u8fd4\u56de\u6709\u57fa\u56e0\u7684SNP\u4fe1\u606f\uff0c\u547d\u4ee4\u5982\u4e0b\uff1a<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">bedtools intersect -a snp.ped -b gene.ped -wa -wb<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.21243523316062177\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/12_kVDjoCFPHo81AibDTXl6kq8wvBfnGA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0GZfjlN02A7iaMCUVia2KVBsYfv6kVDjoCFPHo81AibDTXl6kq8wvBfnGA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"386\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u7ed3\u679c\u53ef\u4ee5\u770b\u5230\uff0c\u6ca1\u6709\u5339\u914d\u5230\u57fa\u56e0\u7684SNP\u90fd\u88ab\u5220\u9664\u4e86\u3002<br \/><\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.3888888888888889\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/13_8icjMcjcVJRw9Qia92jbnYbmr8ibSQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K09AgO9ouoAaLSicqsg4Ba3OibOkkro8icjMcjcVJRw9Qia92jbnYbmr8ibSQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-bottom: 10px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(176, 176, 176);padding: 7px;\">\n<section style=\"justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgba(249, 238, 237, 0.5);padding: 18px;\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"text-align: justify;font-size: 14px;letter-spacing: 2px;line-height: 1.8;\">\n<p style=\"white-space: normal;\">\u597d\u4e86\uff0c\u4eca\u5929\u7684GWAS\u7ed3\u679c\u5982\u4f55\u6ce8\u91caSNP\u5c31\u5230\u8fd9\u91cc\u4e86\uff0c\u5e0c\u671b\u5c0f\u56fe\u7684\u5206\u4eab\u5bf9\u5927\u5bb6\u7684\u79d1\u7814\u5de5\u4f5c\u6709\u6240\u5e2e\u52a9\u3002\u6709\u5174\u8da3\u7684\u670b\u53cb\u53ef\u4ee5\u7ee7\u7eed\u5173\u6ce8\u5c0f\u56fe\u7684\u5fae\u4fe1\u516c\u4f17\u53f7\uff08\u751f\u4fe1\u56fe\uff09\u548c\u96f6\u4ee3\u7801\u4e91\u751f\u4fe1\u751f\u7269\u4fe1\u606f\u5b66\u5e73\u53f0\uff08http:\/\/www.biocloudservice.com\/home.html\uff09\u3002\u5c0f\u4f19\u4f34\u8d76\u7d27\u52a8\u624b\u64cd\u4f5c\u8d77\u6765\uff0c\u770b\u770b\u4eca\u5929\u7684\u5b66\u4e60\u6210\u679c\uff0c\u8bf4\u4e0d\u5b9a\u4f1a\u6210\u4e3a\u4f60\u6587\u7ae0\u4e2d\u7684\u4eae\u70b9\uff0c\u6211\u4eec\u4e0b\u671f\u89c1~<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<\/section>\n<section style=\"text-align: justify;font-size: 14px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u6b22\u8fce\u4f7f\u7528\uff1a\u4e91\u751f\u4fe1\u5e73\u53f0 ( http:\/\/www.biocloudservice.com\/home.html)<\/p>\n<\/section>\n<section style=\"transform: scale(0.5);transform-origin: center center;margin-top: -65px;margin-bottom: -65px;\" powered-by=\"xiumi.us\">\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"1\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-09-23_\u300c\u8f6c\u300dGWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01\/14_JhZ0HxOYMelibCMtkaaUict6BaBWmQ.jpg\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0H4nvZIzLEfMlXLr3QLJxekq94mJhZ0HxOYMelibCMtkaaUict6BaBWmQ\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"258\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"min-height: 40px;margin: 10px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"width: 100%;margin-right: auto;margin-bottom: -10px;margin-left: auto;\">\n<table width=\"100%\">\n<tbody>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:60.classicTable1:0\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:60.classicTable1:0.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;background-color: rgb(249, 174, 165);padding: 10px 0px;\" width=\"96.3700%\">\n<section style=\"line-height: 1;text-align: center;font-size: 17px;color: rgb(255, 255, 255);letter-spacing: 5px;\" powered-by=\"xiumi.us\">\n<p><strong>\u5f80\u671f\u63a8\u8350<\/strong><\/p>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:60.classicTable1:1\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" 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data={\"mp\":\"\u751f\u4fe1\u679c\",\"title\":\"GWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01\",\"time\":\"2023-09-23 19:02:26\",\"timeStamp\":\"1695466946\"};\n<\/script><br \/>\n<body><\/p>\n<div class=\"rich_media\">\n<h1 class=\"rich_media_title\" id=\"activity-name\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247493478&idx=3&sn=953c516d1107acd4da869cf082ab9836&chksm=cf7f77a3f808feb5e4e78021fc10c752605b56d79ab9eb9361fdfb4bee3fcb49f29f36eaf616#rd\" target=\"_blank\" rel=\"noopener\">GWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01<\/a><\/h1>\n<div id=\"meta_content\" class=\"rich_media_meta_list\"><span class=\"rich_media_meta rich_media_meta_text\">\u5c0f\u56fe <\/span><span class=\"rich_media_meta rich_media_meta_nickname\" id=\"profileBt\"><a href=\"javascript:void(0);\" class=\"wx_tap_link js_wx_tap_highlight weui-wa-hotarea\" 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10px;\">\n<section style=\"font-size: 17px;color: rgb(255, 255, 255);text-align: right;letter-spacing: 4px;\" powered-by=\"xiumi.us\">\n<p><strong>\u70b9\u51fb\u84dd\u5b57<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;border-left: 4px solid rgb(242, 183, 183);border-bottom-left-radius: 0px;flex: 100 100 0%;align-self: stretch;height: auto;padding: 3px 10px;background-color: rgba(254, 245, 240, 0.8);\">\n<section style=\"color: rgb(181, 126, 121);font-size: 17px;letter-spacing: 4px;\" powered-by=\"xiumi.us\">\n<p><strong>\u5173\u6ce8\u5c0f\u56fe<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 0em;white-space: normal;\">Bedtools:\u4e00\u4e2a\u5f3a\u5927\u7684\u57fa\u56e0\u7ec4\u7b97\u6cd5\u5de5\u5177\u96c6\uff0c\u7531\u72b9\u4ed6\u5927\u5b66\u6606\u5170\u5b9e\u9a8c\u5ba4\u5f00\u53d1\u7684\u3002\u603b\u7684\u6765\u8bf4\uff0cBedtools\u5de5\u5177\u662f\u4e00\u4e2a\u582a\u79f0\u745e\u58eb\u519b\u5200\u7684\u5de5\u5177\uff0c\u7528\u4e8e\u5e7f\u6cdb\u7684\u57fa\u56e0\u7ec4\u5b66\u5206\u6790\u4efb\u52a1\u3002\u6700\u5e7f\u6cdb\u4f7f\u7528\u7684\u5de5\u5177\u4f7f\u57fa\u56e0\u7ec4\u8fd0\u7b97\u6210\u4e3a\u53ef\u80fd:\u5373\u57fa\u56e0\u7ec4\u7684\u96c6\u5408\u8bba\u3002\u4f8b\u5982\uff0cbedtools\u5141\u8bb8\u4eba\u4eec\u4ece\u5e7f\u6cdb\u4f7f\u7528\u7684\u57fa\u56e0\u7ec4\u6587\u4ef6\u683c\u5f0f\uff08\u5982BAM\u3001BED\u3001GFF\/GTF\u3001VCF\uff09\u7684\u591a\u4e2a\u6587\u4ef6\u4e2d\u4ea4\u53c9\u3001\u5408\u5e76\u3001\u8ba1\u6570\u3001\u8865\u5145\u548c\u6d17\u6362\u57fa\u56e0\u7ec4\u95f4\u9694\u3002\u867d\u7136\u6bcf\u4e2a\u5355\u72ec\u7684\u5de5\u5177\u90fd\u88ab\u8bbe\u8ba1\u4e3a\u6267\u884c\u76f8\u5bf9\u7b80\u5355\u7684\u4efb\u52a1\uff08\u4f8b\u5982\uff0c\u76f8\u4ea4\u4e24\u4e2a\u95f4\u9694\u6587\u4ef6\uff09\uff0c\u4f46\u662f\u53ef\u4ee5\u6267\u884c\u76f8\u5f53\u590d\u6742\u7684\u5206\u6790\u5de5\u4f5c\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u5c0f\u56fe\u4eca\u5929\u7ed9\u5927\u5bb6\u4ecb\u7ecd\u4e24\u79cdBedtools\u5b89\u88c5\u65b9\u6cd5<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K06A9sD59ueQvpZPQauQJWUWUibUUobtCHFlJgpIicJFk8dTb3ajwqOeibA\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>\u7b2c\u4e00\u79cd<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0uuAWvdFASmFcD4MPCRn5Wpib8MIlhvrSJgem2VGvnAWaSvFs35IictNg\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">wget https:<span class=\"code-snippet__comment\">\/\/github.com\/arq5x\/bedtools2\/archive\/v2.25.0.tar.gz<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">tar xzvf v2<span class=\"code-snippet__number\">.25<\/span><span class=\"code-snippet__number\">.0<\/span> <\/span><\/code><code><span class=\"code-snippet_outer\">cd bedtools2<span class=\"code-snippet__number\">-2.25<\/span><span class=\"code-snippet__number\">.0<\/span>\/<\/span><\/code><code><span class=\"code-snippet_outer\">make<\/span><\/code><code><span class=\"code-snippet_outer\">cd bin\/<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u6dfb\u52a0\u73af\u5883\u5373\u53ef<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">export<\/span> PATH=$PWD:$PATH<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K06A9sD59ueQvpZPQauQJWUWUibUUobtCHFlJgpIicJFk8dTb3ajwqOeibA\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>\u7b2c\u4e8c\u79cd<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0uuAWvdFASmFcD4MPCRn5Wpib8MIlhvrSJgem2VGvnAWaSvFs35IictNg\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u4f7f\u7528conda\u5b89\u88c5<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u521b\u5efa\u81ea\u5df1\u7684\u73af\u5883<\/span><\/code><code><span class=\"code-snippet_outer\">source activate mypy <\/span><\/code><code><span class=\"code-snippet_outer\">#\u8fdb\u5165\u81ea\u5df1\u7684\u73af\u5883<\/span><\/code><code><span class=\"code-snippet_outer\"> conda install -c bioconda bedtools<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u4e24\u79cd\u65b9\u6cd5\u6839\u636e\u81ea\u5df1\u5b9e\u9645\u60c5\u51b5\u9009\u62e9<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u9996\u5148\uff0c\u5148\u7528\u793a\u4f8b\u6570\u636e\u4e86\u89e3\u4e00\u4e0b\u5982\u4f55\u53d6\u6570\u636e\u96c6\u4e4b\u95f4\u7684\u4ea4\u96c6\u57fa\u56e0<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.3734015345268542\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_CmNRURFqCqtaNFaAWoSRRUqaric25w.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0krk9d0AfLqwwNJ29lVSxRE7gTCmNRURFqCqtaNFaAWoSRRUqaric25w\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"782\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u4ea4\u96c6 -intersect<\/p>\n<p style=\"white-space: normal;\">gene1.ped\u5185\u5bb9\u4e3a<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.23197492163009403\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-09-23_\u300c\u8f6c\u300dGWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01\/2_tSl9r0QjURic7yQgZanu7Csuhzd9mQ.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K04iaabWprk7aWZD3dbZtJs0LbXFtSl9r0QjURic7yQgZanu7Csuhzd9mQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"319\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">gene2.ped\u5185\u5bb9\u4e3a<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.4105263157894737\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-09-23_\u300c\u8f6c\u300dGWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01\/3_R4EpZYibzibajx3Za7VbHocSKlmpcg.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0ypaaRYyXPtIyAPFWjlzw1btianmR4EpZYibzibajx3Za7VbHocSKlmpcg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"285\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c1\u5217\uff1a\u67d3\u8272\u4f53<\/p>\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c2\u5217\uff1a\u8d77\u59cb\u4f4d\u7f6e<\/p>\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c3\u5217\uff1a\u7ec8\u6b62\u4f4d\u7f6e<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u547d\u4ee4\uff1a<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">bedtools intersect -a gene1.ped -gene2.ped<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u7ed3\u679c\u5982\u4e0b\uff1a<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.4177215189873418\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_EVialPmNuHdyIoRfRbEWksQQSOzorw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0fzia3pzVLPqs8TtsWic1JN9ribdqEVialPmNuHdyIoRfRbEWksQQSOzorw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"158\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u53ef\u89c1\u56db\u4e2a\u91cd\u590d\u533a\u57df<\/p>\n<p style=\"white-space: normal;\">\u7b2c\u4e00\u4e2a\u91cd\u590d\u533a\u57df\u662f10-14<\/p>\n<p style=\"white-space: normal;\">\u7b2c\u4e8c\u4e2a\u91cd\u590d\u533a\u57df\u662f17-19<\/p>\n<p style=\"white-space: normal;\">\u7b2c\u4e09\u4e2a\u91cd\u590d\u533a\u57df\u662f80-82<\/p>\n<p style=\"white-space: normal;\">\u7b2c\u56db\u4e2a\u91cd\u590d\u533a\u57df\u662f88-90<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u5982\u679c\u60f3\u8f93\u51fa\u8ba1\u7b97A\u4e2d\u6709B\u7684\u4ea4\u96c6\u533a\u95f4\uff0c\u540c\u65f6\u8fd4\u56deA\u4e2d\u7684\u7ed3\u679c\uff1a<\/strong><\/p>\n<p style=\"white-space: normal;\"><strong>\u53ef\u52a0 -wa \u53c2\u6570<\/strong><\/p>\n<p style=\"white-space: normal;\"><strong>\u547d\u4ee4\uff1a<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">bedtools intersect -a gene1.ped -gene2.ped -wa<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u7ed3\u679c\u5982\u4e0b\uff1a<br \/><\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.42567567567567566\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_8VJq6mBciafMxaWZYEd1bMWBRYN9kA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0npozv3vxp1uR55NtQCtCZN2Uib8VJq6mBciafMxaWZYEd1bMWBRYN9kA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"148\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u5982\u679c\u60f3\u8f93\u51fa\u8ba1\u7b97A\u4e2d\u6709B\u7684\u4ea4\u96c6\u533a\u95f4\uff0c\u540c\u65f6\u8fd4\u56deB\u4e2d\u7684\u7ed3\u679c\uff1a<\/strong><\/p>\n<p style=\"white-space: normal;\"><strong>\u53ef\u52a0 -wb \u53c2\u6570<\/strong><\/p>\n<p style=\"white-space: normal;\"><strong>\u547d\u4ee4\uff1a <\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">bedtools intersect -a gene1.ped -gene2.ped -wb<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u7ed3\u679c\u5982\u4e0b\uff1a<br \/><\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.2\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-09-23_\u300c\u8f6c\u300dGWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01\/6_LSjiaIepQlcfP46TeJ74ERpxGB0Zpw.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0dEkPTF772VWObL5DKicjRB0WJSLSjiaIepQlcfP46TeJ74ERpxGB0Zpw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"325\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u4ece\u7ed3\u679c\u53ef\u89c1\uff0c\u52a0\u4e0a-wb\u53c2\u6570\u540e\uff0c\u9664\u4e86\u8f93\u51faA\u4e2d\u7684\u4ea4\u96c6\u533a\u57df\u5916\uff0c\u8fd8\u4f1a\u8f93\u51faB\u4e2d\u7684\u6574\u4e2a\u533a\u95f4\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u5982\u679c\u52a0\u4e0a-wa -wb\u53c2\u6570<\/strong><\/p>\n<p style=\"white-space: normal;\"><strong>\u547d\u4ee4\uff1a<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">bedtools intersect -a gene1.ped -gene2.ped -wa -wb<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.2168284789644013\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_9V9Baibf6YYyEtBRPxHnrOqzibe6EQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0iadw487QFB2niawebuoBCicf43XzY9V9Baibf6YYyEtBRPxHnrOqzibe6EQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"309\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">-c\u53c2\u6570\uff0c\u7edf\u8ba1A\u4e2d\u6bcf\u4e2a\u533a\u57df\u4e0eB\u91cd\u53e0\u7684\u6b21\u6570<\/p>\n<p style=\"white-space: normal;\">\u547d\u4ee4\uff1abedtools intersect -a gene1.ped -gene2.ped -c<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.2620320855614973\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-09-23_\u300c\u8f6c\u300dGWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01\/8_jibFulVRIS5sO7HfywE3e9CvVzqXnQ.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0KCWwYw5HNNHjQJF213BbZkj3ejibFulVRIS5sO7HfywE3e9CvVzqXnQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"187\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u7531\u7ed3\u679c\u53ef\u770b\u51fa\uff0c\u5728A\u6587\u4ef6\u4e2d\u67d3\u8272\u4f53\u4f4d\u7f6e\u548c\u6709\u591a\u5c11B\u6587\u4ef6\u67d3\u8272\u4f53\u4f4d\u7f6e\u4e0e\u5176\u6709\u91cd\u53e0\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"text-indent: 0em;white-space: normal;\">\u90a3\u4e48\uff0cGWAS\u5206\u6790\u5982\u4f55\u8fdb\u884csnp\u5982\u4f55\u505a\u6ce8\u91ca\uff0cGWAS\u5206\u6790\u4e2d\uff0c\u6211\u4eec\u7528\u57fa\u56e0\u578b\u6570\u636e\uff08SNP\uff09+\u8868\u578b\u6570\u636e\uff0c\u8fdb\u884c\u5173\u8054\u5206\u6790\uff0c\u5f97\u5230\u663e\u8457\u6027\u7684SNP\uff0c\u8fd9\u4e9bSNP\u6709\u67d3\u8272\u4f53\u548c\u7269\u7406\u4f4d\u7f6e\uff0c\u90a3\u4e48\u6211\u4eec\u5982\u4f55\u5bf9SNP\u8fdb\u884c\u57fa\u56e0\u6ce8\u91ca\u5462\uff1f\u6211\u4eec\u5982\u4f55\u5f97\u5230\u663e\u8457SNP\u9644\u8fd1\u7684\u57fa\u56e0\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u4ea4\u96c6 -intersect<\/p>\n<p style=\"white-space: normal;\">gene.ped\u5185\u5bb9\u4e3a<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.34309623430962344\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_3bcnxqRNgoSb7TNG8CZMsHjWAlib9w.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0dHC6oVnwYf30z7o8hFJ8IIibMt3bcnxqRNgoSb7TNG8CZMsHjWAlib9w\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"478\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c1\u5217\uff1a\u67d3\u8272\u4f53<\/p>\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c2\u5217\uff1a\u8d77\u59cb\u4f4d\u7f6e<\/p>\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c3\u5217\uff1a\u7ec8\u6b62\u4f4d\u7f6e<\/p>\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c4\u5217\uff1a\u7ec8\u6b62\u4f4d\u7f6e<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">snp.ped\u5185\u5bb9\u4e3a<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.5192878338278932\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-09-23_\u300c\u8f6c\u300dGWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01\/10_VCPgLIHkTT8Bu9aHGpGk73IcFVQQjg.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0iaYozVS7ibyFJEq9OnLyqG5NhQVCPgLIHkTT8Bu9aHGpGk73IcFVQQjg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"337\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c1\u5217\uff1a\u67d3\u8272\u4f53<\/p>\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c2\u5217\uff1a\u8d77\u59cb\u4f4d\u7f6e<\/p>\n<p style=\"white-space: normal;\">\u6570\u636e\u7b2c3\u5217\uff1a\u7ec8\u6b62\u4f4d\u7f6e<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u547d\u4ee4\uff1a<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">bedtools intersect -a snp.ped -b gene.ped -loj<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">intersect\uff0c\u4ea4\u96c6<br \/><\/p>\n<p style=\"white-space: normal;\">-a\uff0c\u7b2c\u4e00\u4e2a\u4f4d\u7f6e\u4fe1\u606f\u8868<\/p>\n<p style=\"white-space: normal;\">-b\uff0c\u7b2c\u4e8c\u4e2a\u4f4d\u7f6e\u4fe1\u606f\u8868<\/p>\n<p style=\"white-space: normal;\">-loj\uff0c\u4ee5\u7b2c\u4e00\u4e2a\u4e3a\u57fa\u51c6\uff0c\u8fd4\u56de\u7ed3\u679c<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.3112745098039216\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-09-23_\u300c\u8f6c\u300dGWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01\/11_5hauCNpQCSIR8akhY7h1J6f37yUYNg.png\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0Qb2LM68LzjI8CL0TpRc5lkPn5hauCNpQCSIR8akhY7h1J6f37yUYNg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"408\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u7ed3\u679c\u53ef\u4ee5\u770b\u5230\uff0c\u7b2c\u4e8c\u4e2aSNP\u533a\u95f4\uff0c\u5bf9\u5e94\u4e24\u4e2a\u57fa\u56e0\uff0c\u5199\u6210\u4e86\u4e24\u884c\u3002\u7b2c\u4e09\u4e2aSNP\u533a\u95f4\u6ca1\u6709\u5bf9<\/p>\n<p style=\"white-space: normal;\">\u5e94\u57fa\u56e0\uff0c\u7528-1\u8868\u793a\u5360\u4f4d\u3002\u5171\u8fd4\u56de8\u884c\u4fe1\u606f\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\"><span style=\"color: rgb(225, 109, 109);\"><strong>\u6ce8\u610f\uff1a<\/strong><\/span>\u6bcf\u4e2aSNP\u4e00\u884c\uff0c\u5982\u679c\u6709\u57fa\u56e0\u5728\u5176\u533a\u95f4\uff0c\u653e\u5230\u53f3\u8fb9\uff0c\u5982\u679c\u6ca1\u6709\u57fa\u56e0\uff0c\u8fd4\u56de\u7a7a\u3002\u5982\u679c\u4e00\u4e2aSNP\u533a\u95f4\u5bf9\u5e94\u591a\u4e2a\u57fa\u56e0\uff0c\u5199\u6210\u591a\u884c\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.8;text-align: justify;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\"><strong>\u5982\u679c\u4e0d\u60f3\u8981\u8fd4\u56de\u7a7a\u503c\uff0c\u53ea\u60f3\u8fd4\u56de\u6709\u57fa\u56e0\u7684SNP\u4fe1\u606f\uff0c\u547d\u4ee4\u5982\u4e0b\uff1a<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">bedtools intersect -a snp.ped -b gene.ped -wa -wb<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.21243523316062177\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/12_kVDjoCFPHo81AibDTXl6kq8wvBfnGA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0GZfjlN02A7iaMCUVia2KVBsYfv6kVDjoCFPHo81AibDTXl6kq8wvBfnGA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"386\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: 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left;justify-content: flex-start;display: flex;flex-flow: row;margin-bottom: 10px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(176, 176, 176);padding: 7px;\">\n<section style=\"justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgba(249, 238, 237, 0.5);padding: 18px;\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"text-align: justify;font-size: 14px;letter-spacing: 2px;line-height: 1.8;\">\n<p style=\"white-space: normal;\">\u597d\u4e86\uff0c\u4eca\u5929\u7684GWAS\u7ed3\u679c\u5982\u4f55\u6ce8\u91caSNP\u5c31\u5230\u8fd9\u91cc\u4e86\uff0c\u5e0c\u671b\u5c0f\u56fe\u7684\u5206\u4eab\u5bf9\u5927\u5bb6\u7684\u79d1\u7814\u5de5\u4f5c\u6709\u6240\u5e2e\u52a9\u3002\u6709\u5174\u8da3\u7684\u670b\u53cb\u53ef\u4ee5\u7ee7\u7eed\u5173\u6ce8\u5c0f\u56fe\u7684\u5fae\u4fe1\u516c\u4f17\u53f7\uff08\u751f\u4fe1\u56fe\uff09\u548c\u96f6\u4ee3\u7801\u4e91\u751f\u4fe1\u751f\u7269\u4fe1\u606f\u5b66\u5e73\u53f0\uff08http:\/\/www.biocloudservice.com\/home.html\uff09\u3002\u5c0f\u4f19\u4f34\u8d76\u7d27\u52a8\u624b\u64cd\u4f5c\u8d77\u6765\uff0c\u770b\u770b\u4eca\u5929\u7684\u5b66\u4e60\u6210\u679c\uff0c\u8bf4\u4e0d\u5b9a\u4f1a\u6210\u4e3a\u4f60\u6587\u7ae0\u4e2d\u7684\u4eae\u70b9\uff0c\u6211\u4eec\u4e0b\u671f\u89c1~<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<\/section>\n<section style=\"text-align: justify;font-size: 14px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u6b22\u8fce\u4f7f\u7528\uff1a\u4e91\u751f\u4fe1\u5e73\u53f0 ( http:\/\/www.biocloudservice.com\/home.html)<\/p>\n<\/section>\n<section style=\"transform: scale(0.5);transform-origin: center center;margin-top: -65px;margin-bottom: -65px;\" powered-by=\"xiumi.us\">\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"1\" data-s=\"300,640\" src=\"\u56fe\u7247\/\u751f\u4fe1\u679c_2023-09-23_\u300c\u8f6c\u300dGWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01\/14_JhZ0HxOYMelibCMtkaaUict6BaBWmQ.jpg\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QucCP4cJVsl08JKjfo9q5K0H4nvZIzLEfMlXLr3QLJxekq94mJhZ0HxOYMelibCMtkaaUict6BaBWmQ\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"258\" style=\"vertical-align: middle;width: 100%;\" \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"min-height: 40px;margin: 10px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"width: 100%;margin-right: auto;margin-bottom: -10px;margin-left: auto;\">\n<table width=\"100%\">\n<tbody>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:60.classicTable1:0\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:60.classicTable1:0.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;background-color: rgb(249, 174, 165);padding: 10px 0px;\" width=\"96.3700%\">\n<section style=\"line-height: 1;text-align: center;font-size: 17px;color: rgb(255, 255, 255);letter-spacing: 5px;\" powered-by=\"xiumi.us\">\n<p><strong>\u5f80\u671f\u63a8\u8350<\/strong><\/p>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:60.classicTable1:1\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" 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href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247485141&idx=1&sn=59b0df7b23a26f8a93ea394192e6344f&chksm=c1b17b28f6c6f23ecd9e87265e008d9ec1193582abf95fbe39f6e9eb8667ab8e34c391770b5d&scene=21#wechat_redirect\" textvalue=\"\u542c\u8bf4\u53ef\u4ee5\u7528R\u8bed\u8a00\u5b8c\u6210\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u9057\u4f20\u76f8\u5173\uff0c\u4f60\u6765\u4e0d\u6765\u5b66\uff1f\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u542c\u8bf4\u53ef\u4ee5\u7528R\u8bed\u8a00\u5b8c\u6210\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u9057\u4f20\u76f8\u5173\uff0c\u4f60\u6765\u4e0d\u6765\u5b66\uff1f<\/a><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\">\ud83d\udc47\u70b9\u51fb\u9605\u8bfb\u539f\u6587\u8fdb\u5165\u7f51\u5740<\/p>\n<\/section>\n<p style=\"display: none;margin-bottom: 24px;\"><mp-style-type data-value=\"3\"><\/mp-style-type><\/p>\n<div class=\"msg_source_url\"><a href=\"http:\/\/www.biocloudservice.com\/home.html\" target=\"_blank\" rel=\"noopener\">\u9605\u8bfb\u539f\u6587<\/a><\/div>\n<p><\/content><\/p>\n<div class=\"msg_source_url\"><a href=\"http:\/\/www.biocloudservice.com\/home.html\" target=\"_blank\" rel=\"noopener\">\u9605\u8bfb\u539f\u6587<\/a><\/div>\n<\/div>\n<p><\/body><br \/>\n<\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>GWAS\u7ed3\u679c\u4e2dSNP\u4e0d\u4f1a\u6ce8\u91ca\u600e\u4e48\u529e\uff1fBedtools\u8bf4\u597d\u529e\uff01 \u5c0f\u56fe \u751f\u4fe1\u679c & […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/57117"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=57117"}],"version-history":[{"count":1,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/57117\/revisions"}],"predecessor-version":[{"id":57134,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/57117\/revisions\/57134"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=57117"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=57117"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=57117"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}