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rich_media_meta_text\">\u5c0f\u679c <\/span><span class=\"rich_media_meta rich_media_meta_nickname\" id=\"profileBt\"><a href=\"javascript:void(0);\" class=\"wx_tap_link js_wx_tap_highlight weui-wa-hotarea\" id=\"js_name\">\u751f\u4fe1\u679c <\/a><\/span><em id=\"publish_time\" class=\"rich_media_meta rich_media_meta_text\">2023-10-11 19:01:00<\/em><\/div>\n<p><content><\/p>\n<div class=\"topic\">\n<p>\u6536\u5f55\u4e8e\u8bdd\u9898<\/p>\n<p><a href=\"https:\/\/mp.weixin.qq.com\/mp\/appmsgalbum?__biz=Mzg3OTg3MjQyNg==&action=getalbum&album_id=2812010014583390210#wechat_redirect\" title=\"R\u4ee3\u7801\" target=\"_blank\" rel=\"noopener\">#R\u4ee3\u7801<\/a><a href=\"https:\/\/mp.weixin.qq.com\/mp\/appmsgalbum?__biz=Mzg3OTg3MjQyNg==&action=getalbum&album_id=2821072943068839938#wechat_redirect\" title=\"\u751f\u4fe1\u7ed8\u56fe\" target=\"_blank\" rel=\"noopener\">#\u751f\u4fe1\u7ed8\u56fe<\/a><a href=\"https:\/\/mp.weixin.qq.com\/mp\/appmsgalbum?__biz=Mzg3OTg3MjQyNg==&action=getalbum&album_id=2664545260517294084#wechat_redirect\" title=\"\u751f\u4fe1\u5b9e\u64cd\" target=\"_blank\" rel=\"noopener\">#\u751f\u4fe1\u5b9e\u64cd<\/a><\/p>\n<\/div>\n<section data-mpa-powered-by=\"yiban.io\">\n<section powered-by=\"xiumi.us\">\n<section>\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section>\n<section powered-by=\"xiumi.us\">\n<section powered-by=\"xiumi.us\">\n<section>\n<p style=\"text-align: left;\"><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;letter-spacing: 0.034em;\">\u4eca\u5929\u5c0f\u679c\u4e3a\u5927\u5bb6\u5e26\u6765\u7684\u5206\u4eab\u5185\u5bb9\u4e3aNomogram\u6a21\u578b\u7684\u6784\u5efa\u548c\u9a8c\u8bc1\uff0c\u8be5\u5206\u6790\u5728\u80bf\u7624\u751f\u4fe1\u6587\u7ae0\u4e2d\u51fa\u73b0\u7684\u9891\u7387\u975e\u5e38\u9ad8\uff0c\u5c0f\u679c\u672c\u63a8\u6587\u4e2d\u4e3b\u8981\u7ed8\u5236\u4e86\u5217\u7ebf\u56fe\u548c\u6821\u6b63\u66f2\u7ebf\u7ed8\u5236\uff0c\u5e72\u8d27\u6ee1\u6ee1\uff0c\u975e\u5e38\u503c\u5f97\u5c0f\u4f19\u4f34\u5b66\u4e60\uff0c\u63a5\u4e0b\u6765\u8ddf\u7740\u5c0f\u679c\u9a6c\u4e0a\u5f00\u59cb\u4eca\u5929\u7684\u5b66\u4e60\uff01<\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;letter-spacing: 0.034em;\"><br \/><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\">\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;font-size: 16px;\" mpa-from-tpl=\"t\">\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;align-self: flex-end;flex: 0 0 auto;border-style: solid;border-width: 0px 0px 7px;border-bottom-color: rgb(175, 225, 255);min-width: 5%;height: auto;\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;font-size: 20px;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<p><strong mpa-from-tpl=\"t\" mpa-is-content=\"t\"><strong>1.<\/strong><strong>\u4f55\u4e3a<\/strong><strong>nomogram\u5206\u6790\uff1f<\/strong><\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 5%;flex: 0 0 auto;height: auto;align-self: flex-end;\" mpa-from-tpl=\"t\">\n<section style=\"transform: perspective(0px);transform-style: flat;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<section style=\"transform: translate3d(5px, 0px, 0px) rotateX(180deg);\" mpa-from-tpl=\"t\">\n<section style=\"display: inline-block;width: 6px;height: 6px;vertical-align: top;overflow: hidden;border-radius: 460px;background-color: rgb(244, 171, 189);\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<p><br mpa-from-tpl=\"t\" \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: left;\"><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;letter-spacing: 0.034em;text-align: justify;\">\u5728\u8fdb\u884c\u5206\u6790\u4e4b\u524d\uff0c\u5c0f\u679c\u5148\u4e3a\u5c0f\u4f19\u4f34\u4ecb\u7ecd\u4e00\u4e0bnomogram\u539f\u7406\uff0cnomogram\u5b9e\u8d28\u5c31\u662f\u56de\u5f52\u65b9\u7a0b\u7684\u53ef\u89c6\u5316\uff0c\u6839\u636e\u6240\u6709\u81ea\u53d8\u91cf\u56de\u5f52\u7cfb\u6570\u7684\u5927\u5c0f\u6765\u5236\u5b9a\u8bc4\u5206\u6807\u51c6\uff0c\u7ed9\u6bcf\u4e2a\u81ea\u53d8\u91cf\u7684\u6bcf\u79cd\u53d6\u503c\u6c34\u5e73\u4e00\u4e2a\u8bc4\u5206\uff0c\u5bf9\u6bcf\u4e2a\u6837\u672c\u5c31\u53ef\u8ba1\u7b97\u5f97\u5230\u4e00\u4e2a\u603b\u5206\uff0c\u518d\u901a\u8fc7\u5f97\u5206\u4e0e\u7ed3\u5c40\u53d1\u751f\u6982\u7387\u4e4b\u95f4\u7684\u8f6c\u6362\u51fd\u6570\u6765\u8ba1\u7b97\u6bcf\u4e2a\u6837\u672c\u7684\u7ed3\u5c40\u65f6\u95f4\u53d1\u751f\u7684\u6982\u7387\uff0c\u6211\u4eec\u901a\u8fc7Nomogram\u7684\u65b9\u6cd5\u5f97\u5230\u7684\u6982\u7387\u8bc4\u4ef7\u9884\u6d4b\u76ee\u6807\u72ec\u7acb\u751f\u5b58\u9884\u540e\u56e0\u7d20\u4e0e\u9884\u540e\u95f4\u7684\u76f8\u5173\u6027\u53ca\u5bf9\u751f\u5b58\u9884\u540e\u7684\u9884\u6d4b\u5173\u7cfb\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;letter-spacing: 0.034em;text-align: justify;\">\u4ee5\u4e0a\u5c31\u662f\u5c0f\u679c\u5bf9nomogram\u7684\u4ecb\u7ecd\uff0c\u5c0f\u4f19\u4f34\u4eec\u6709\u6ca1\u6709\u7406\u89e3\u5440\uff01<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;letter-spacing: 0.034em;text-align: justify;\">\u9a6c\u4e0a\u548c\u5c0f\u679c\u5f00\u542f\u5b9e\u64cd\u7ec3\u4e60\u5427\uff01<\/span><br \/><\/p>\n<p><span style=\"\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\"><em style=\"font-size: 15px;white-space: normal;color: rgb(178, 178, 178);letter-spacing: 0.578px;\"><span style=\"font-size: 13px;text-decoration: underline;\">\u516c\u4f17\u53f7\u540e\u53f0\u56de\u590d\u201c111″,\u9886\u53d6\u4ee3\u7801\uff0c\u4ee3\u7801\u7f16\u53f7\uff1a231005<\/span><\/em><\/span><\/p>\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\">\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;font-size: 16px;\" mpa-from-tpl=\"t\">\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;align-self: flex-end;flex: 0 0 auto;border-style: solid;border-width: 0px 0px 7px;border-bottom-color: rgb(175, 225, 255);min-width: 5%;height: auto;\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;font-size: 20px;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<p><strong mpa-from-tpl=\"t\" mpa-is-content=\"t\">2.\u51c6\u5907\u9700\u8981\u7684R\u5305<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 5%;flex: 0 0 auto;height: auto;align-self: flex-end;\" mpa-from-tpl=\"t\">\n<section style=\"transform: perspective(0px);transform-style: flat;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<section style=\"transform: translate3d(5px, 0px, 0px) rotateX(180deg);\" mpa-from-tpl=\"t\">\n<section style=\"display: inline-block;width: 6px;height: 6px;vertical-align: top;overflow: hidden;border-radius: 460px;background-color: rgb(244, 171, 189);\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<p><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;\"><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 20px;\"><\/span><\/p>\n<h2 style=\"text-align: center;\"><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\"><o:p><\/o:p><\/span><\/h2>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"sql\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u5b89\u88c5\u9700\u8981\u7684R\u5305<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">install.packages(<span class=\"code-snippet__string\">\"rms\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">install.packages(<span class=\"code-snippet__string\">\"survival\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u52a0\u8f7d\u9700\u8981\u7684R\u5305<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">library<\/span>(rms)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">library<\/span>(survival)<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.3888888888888889\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_IlmBAWe69EMUPMhNEgrv6NXX85lJxg-21.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAwyrj7kbUR3ULG9ZUbLrLkgibzL8qUpQROfe8ebc3gNSnu1dIlmBAWe69EMUPMhNEgrv6NXX85lJxg\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"1080\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\">\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;font-size: 16px;\" mpa-from-tpl=\"t\">\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;align-self: flex-end;flex: 0 0 auto;border-style: solid;border-width: 0px 0px 7px;border-bottom-color: rgb(175, 225, 255);min-width: 5%;height: auto;\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;font-size: 20px;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<p><strong mpa-from-tpl=\"t\" mpa-is-content=\"t\">3.\u8bfb\u53d6\u8f93\u5165\u6570\u636e<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 5%;flex: 0 0 auto;height: auto;align-self: flex-end;\" mpa-from-tpl=\"t\">\n<section style=\"transform: perspective(0px);transform-style: flat;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<section style=\"transform: translate3d(5px, 0px, 0px) rotateX(180deg);\" mpa-from-tpl=\"t\">\n<section style=\"display: inline-block;width: 6px;height: 6px;vertical-align: top;overflow: hidden;border-radius: 460px;background-color: rgb(244, 171, 189);\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<p><br mpa-from-tpl=\"t\" \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: left;font-size: 16px;\"><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;letter-spacing: 0.034em;text-align: justify;\">#\u884c\u540d\u4e3a\u6837\u672c\u540d\uff0c\u5217\u540d\u4e3a\u4e34\u5e8a\u56e0\u7d20<\/span><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\"><o:p><\/o:p><\/span><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"css\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__selector-tag\">pbc<\/span><<span class=\"code-snippet__selector-tag\">-read<\/span><span class=\"code-snippet__selector-class\">.table<\/span>(\"<span class=\"code-snippet__selector-tag\">Nomogram<\/span><span class=\"code-snippet__selector-class\">.txt<\/span>\")<\/span><\/code><\/pre>\n<\/section>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\"><\/span><span style=\"\"><o:p><\/o:p><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.2630057803468208\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_bpkmp7ZgNW0CKGVyvLAy7XFJzaqTww.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyBMiaebYV0wRXKtNfxorecdCl3Ixx7OEQURVkzfqaic6bUzmibpkmp7ZgNW0CKGVyvLAy7XFJzaqTww\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"692\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"php\"><code><span class=\"code-snippet_outer\">#\u5bf9bili\u5217\u8fdb\u884c\u6570\u636e\u5206\u5272<\/span><\/code><code><span class=\"code-snippet_outer\">pbc$catbili <- cut(pbc$bili,breaks=c(-Inf, 2, 4, Inf),<\/span><\/code><code><span class=\"code-snippet_outer\"> labels=c(\"low\",\"medium\",\"high\"))<\/span><\/code><code><span class=\"code-snippet_outer\">#\u589e\u52a0\u65b0\u7684\u5217<\/span><\/code><code><span class=\"code-snippet_outer\">pbc$died <- pbc$status==2<\/span><\/code><code><span class=\"code-snippet_outer\">4.Nomogram\u5206\u6790<\/span><\/code><code><span class=\"code-snippet_outer\">dd<-datadist(pbc)<\/span><\/code><code><span class=\"code-snippet_outer\">options(datadist=\"dd\")<\/span><\/code><code><span class=\"code-snippet_outer\">options(na.action=\"na.delete\")<\/span><\/code><code><span class=\"code-snippet_outer\">#\u591a\u56e0\u7d20cox\u56de\u5f52<\/span><\/code><code><span class=\"code-snippet_outer\">coxpbc<-cph(formula = Surv(time,died) ~ age + catbili + sex + copper + stage + trt ,data=pbc,x=T,y=T,surv = T,na.action=na.delete)<\/span><\/code><code><span class=\"code-snippet_outer\">surv<-Survival(coxpbc)<\/span><\/code><code><span class=\"code-snippet_outer\">#5\u5e74\u751f\u5b58\u7387<\/span><\/code><code><span class=\"code-snippet_outer\">surv3<-function(x) surv(1825,x)<\/span><\/code><code><span class=\"code-snippet_outer\">#8\u5e74\u751f\u5b58\u7387<\/span><\/code><code><span class=\"code-snippet_outer\">surv4<-function(x) surv(2920,x)<\/span><\/code><code><span class=\"code-snippet_outer\">x<-nomogram(coxpbc,fun = list(surv3,surv4),lp=T,<\/span><\/code><code><span class=\"code-snippet_outer\"> funlabel = c('5-year survival Probability','8-year survival Probability'),<\/span><\/code><code><span class=\"code-snippet_outer\"> maxscale = 100,fun.at = c(0.95,0.9,0.8,0.7,0.6,0.5,0.4,0.3,0.2,0.1))<\/span><\/code><code><span class=\"code-snippet_outer\">#\u7ed8\u5236\u5217\u7ebf\u56fe<\/span><\/code><code><span class=\"code-snippet_outer\">pdf(\"nomogram_classical.pdf\",width = 12,height = 10)<\/span><\/code><code><span class=\"code-snippet_outer\">plot(x, lplabel=\"Linear Predictor\",<\/span><\/code><code><span class=\"code-snippet_outer\"> xfrac=.35,varname.label=TRUE, varname.label.sep=\"=\", ia.space=.2, <\/span><\/code><code><span class=\"code-snippet_outer\"> tck=NA, tcl=-0.20, lmgp=0.3,<\/span><\/code><code><span class=\"code-snippet_outer\"> points.label='Points', total.points.label='Total Points',<\/span><\/code><code><span class=\"code-snippet_outer\"> total.sep.page=FALSE, <\/span><\/code><code><span class=\"code-snippet_outer\"> cap.labels=FALSE,cex.var = 1.6,cex.axis = 1.05,lwd=5,<\/span><\/code><code><span class=\"code-snippet_outer\"> label.every = 1,col.grid = gray(c(0.8, 0.95)))<\/span><\/code><code><span class=\"code-snippet_outer\">dev.off()<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.8294797687861272\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_yO2mNfx1oszReOqict1AUXXUW308Dg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyBMiaebYV0wRXKtNfxorecdlrL1xjE01YpJb7WbrFC2qxgDkyO2mNfx1oszReOqict1AUXXUW308Dg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"692\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\">\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;font-size: 16px;\" mpa-from-tpl=\"t\">\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;align-self: flex-end;flex: 0 0 auto;border-style: solid;border-width: 0px 0px 7px;border-bottom-color: rgb(175, 225, 255);min-width: 5%;height: auto;\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;font-size: 20px;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<p><strong mpa-from-tpl=\"t\" mpa-is-content=\"t\">4.\u7ed8\u5236\u6821\u6b63\u66f2\u7ebf\u8fdb\u884c\u9a8c\u8bc1<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 5%;flex: 0 0 auto;height: auto;align-self: flex-end;\" mpa-from-tpl=\"t\">\n<section style=\"transform: perspective(0px);transform-style: flat;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<section style=\"transform: translate3d(5px, 0px, 0px) rotateX(180deg);\" mpa-from-tpl=\"t\">\n<section style=\"display: inline-block;width: 6px;height: 6px;vertical-align: top;overflow: hidden;border-radius: 460px;background-color: rgb(244, 171, 189);\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<p><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;font-size: 16px;\"><span style=\"font-size: 20px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><\/span><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"cs\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#5\u5e74\u751f\u5b58\u7387\u6821\u6b63\u66f2\u7ebf<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">f5<-cph(formula = Surv(time,died) ~ age + catbili + sex + copper +stage + trt,data=pbc,x=T,y=T,surv = T,na.action=na.delete,time.inc = <span class=\"code-snippet__number\">1825<\/span>) <\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#\u53c2\u6570m=50\u8868\u793a\u6bcf\u7ec450\u4e2a\u6837\u672c\u8fdb\u884c\u91cd\u590d\u8ba1\u7b97<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">cal5<-calibrate(f5, cmethod=<span class=\"code-snippet__string\">\"KM\"<\/span>, method=<span class=\"code-snippet__string\">\"boot\"<\/span>,u=<span class=\"code-snippet__number\">1825<\/span>,m=<span class=\"code-snippet__number\">50<\/span>,B=<span class=\"code-snippet__number\">1000<\/span>) <\/span><\/code><code><span class=\"code-snippet_outer\">pdf(<span class=\"code-snippet__string\">\"calibration_5y.pdf\"<\/span>,width = <span class=\"code-snippet__number\">8<\/span>,height = <span class=\"code-snippet__number\">8<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">plot(cal5,<\/span><\/code><code><span class=\"code-snippet_outer\"> lwd = <span class=\"code-snippet__number\">2<\/span>,<span class=\"code-snippet__meta\">#<span class=\"code-snippet__meta-keyword\">error<\/span> bar\u7684\u7c97\u7ec6<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> lty = <span class=\"code-snippet__number\">2<\/span>,<span class=\"code-snippet__meta\">#<span class=\"code-snippet__meta-keyword\">error<\/span> bar\u7684\u7c7b\u578b\uff0c\u53ef\u4ee5\u662f0-6<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> errbar.col = c(<span class=\"code-snippet__string\">\"#2166AC\"<\/span>),<span class=\"code-snippet__meta\">#<span class=\"code-snippet__meta-keyword\">error<\/span> bar\u7684\u989c\u8272<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> xlim = c(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>),ylim= c(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> xlab = <span class=\"code-snippet__string\">\"Nomogram-prediced OS (%)\"<\/span>,ylab = <span class=\"code-snippet__string\">\"Observed OS (%)\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> cex.lab=<span class=\"code-snippet__number\">1.2<\/span>, cex.axis=<span class=\"code-snippet__number\">1<\/span>, cex.main=<span class=\"code-snippet__number\">1.2<\/span>, cex.sub=<span class=\"code-snippet__number\">0.6<\/span>) <span class=\"code-snippet__meta\">#\u5b57\u7684\u5927\u5c0f<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">lines(cal5[,c(<span class=\"code-snippet__string\">'mean.predicted'<\/span>,<span class=\"code-snippet__string\">\"KM\"<\/span>)], <\/span><\/code><code><span class=\"code-snippet_outer\"> type = <span class=\"code-snippet__string\">'b'<\/span>, <span class=\"code-snippet__meta\">#\u8fde\u7ebf\u7684\u7c7b\u578b\uff0c\u53ef\u4ee5\u662f\"p\",\"b\",\"o\"<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> lwd = <span class=\"code-snippet__number\">2<\/span>, <span class=\"code-snippet__meta\">#\u8fde\u7ebf\u7684\u7c97\u7ec6<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> pch = <span class=\"code-snippet__number\">16<\/span>, <span class=\"code-snippet__meta\">#\u70b9\u7684\u5f62\u72b6\uff0c\u53ef\u4ee5\u662f0-20<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> col = c(<span class=\"code-snippet__string\">\"#2166AC\"<\/span>)) <span class=\"code-snippet__meta\">#\u8fde\u7ebf\u7684\u989c\u8272<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">mtext(<span class=\"code-snippet__string\">\"\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">box(lwd = <span class=\"code-snippet__number\">1<\/span>) <span class=\"code-snippet__meta\">#\u8fb9\u6846\u7c97\u7ec6<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">abline(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>,lty = <span class=\"code-snippet__number\">3<\/span>, <span class=\"code-snippet__meta\">#\u5bf9\u89d2\u7ebf\u4e3a\u865a\u7ebf<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> lwd = <span class=\"code-snippet__number\">2<\/span>, <span class=\"code-snippet__meta\">#\u5bf9\u89d2\u7ebf\u7684\u7c97\u7ec6<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> col = c(<span class=\"code-snippet__string\">\"#224444\"<\/span>)<span class=\"code-snippet__meta\">#\u5bf9\u89d2\u7ebf\u7684\u989c\u8272<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> ) <\/span><\/code><code><span class=\"code-snippet_outer\">dev.off()<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"1.004106776180698\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_nEicVvEeDsW4AjibzZLP3ZXva0Nw1Q.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyBMiaebYV0wRXKtNfxorecdblToBfyfS8fxJN4icicqSSd4AD5ibnEicVvEeDsW4AjibzZLP3ZXva0Nw1Q\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"487\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"swift\"><code><span class=\"code-snippet_outer\">#<span class=\"code-snippet__number\">8<\/span>\u5e74\u751f\u5b58\u7387\u6821\u6b63\u66f2\u7ebf,time.inc = <span class=\"code-snippet__number\">2920<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">f8<-cph(formula = <span class=\"code-snippet__type\">Surv<\/span>(time,died) ~ age + catbili + sex + copper +stage + trt,data=pbc,x=<span class=\"code-snippet__type\">T<\/span>,y=<span class=\"code-snippet__type\">T<\/span>,surv = <span class=\"code-snippet__type\">T<\/span>,na.action=na.delete,time.inc = <span class=\"code-snippet__number\">2920<\/span>) <\/span><\/code><code><span class=\"code-snippet_outer\">cal8<-calibrate(f8, cmethod=<span class=\"code-snippet__string\">\"KM\"<\/span>, method=<span class=\"code-snippet__string\">\"boot\"<\/span>,u=<span class=\"code-snippet__number\">2920<\/span>,m=<span class=\"code-snippet__number\">50<\/span>,<span class=\"code-snippet__type\">B<\/span>=<span class=\"code-snippet__number\">1000<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">pdf(<span class=\"code-snippet__string\">\"calibration_8y.pdf\"<\/span>,width = <span class=\"code-snippet__number\">8<\/span>,height = <span class=\"code-snippet__number\">8<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">plot(cal8,<\/span><\/code><code><span class=\"code-snippet_outer\"> lwd = <span class=\"code-snippet__number\">2<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> lty = <span class=\"code-snippet__number\">4<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> errbar.col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#B2182B\"<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> xlim = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>),ylim= <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> xlab = <span class=\"code-snippet__string\">\"Nomogram-prediced OS (%)\"<\/span>,ylab = <span class=\"code-snippet__string\">\"Observed OS (%)\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#B2182B\"<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> cex.lab=<span class=\"code-snippet__number\">1.2<\/span>,cex.axis=<span class=\"code-snippet__number\">1<\/span>, cex.main=<span class=\"code-snippet__number\">1.2<\/span>, cex.sub=<span class=\"code-snippet__number\">0.6<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">lines(cal8[,<span class=\"code-snippet__built_in\">c<\/span>('mean.predicted',<span class=\"code-snippet__string\">\"KM\"<\/span>)],<\/span><\/code><code><span class=\"code-snippet_outer\"> type= 'b',<\/span><\/code><code><span class=\"code-snippet_outer\"> lwd = <span class=\"code-snippet__number\">2<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#B2182B\"<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> pch = <span class=\"code-snippet__number\">16<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">mtext(<span class=\"code-snippet__string\">\"\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">box(lwd = <span class=\"code-snippet__number\">1<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">abline(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>,lty= <span class=\"code-snippet__number\">3<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> lwd = <span class=\"code-snippet__number\">2<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> col =<span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#224444\"<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\">dev.off()<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"1\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_rSLq2TXfiaj8O3uyrEWpEGwiaZ1cpg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyBMiaebYV0wRXKtNfxorecd1zHo92RnpCFsiba6pzjMCTeFfgerSLq2TXfiaj8O3uyrEWpEGwiaZ1cpg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"645\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"swift\"><code><span class=\"code-snippet_outer\">#\u7ed8\u5236<span class=\"code-snippet__number\">5<\/span>\u5e74\u548c<span class=\"code-snippet__number\">8<\/span>\u5e74\u751f\u5b58\u7387\u6821\u6b63\u66f2\u7ebf<\/span><\/code><code><span class=\"code-snippet_outer\">pdf(<span class=\"code-snippet__string\">\"calibration_compare.pdf\"<\/span>,width = <span class=\"code-snippet__number\">8<\/span>,height = <span class=\"code-snippet__number\">8<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">plot(cal5,lwd = <span class=\"code-snippet__number\">2<\/span>,lty = <span class=\"code-snippet__number\">0<\/span>,errbar.col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#2166AC\"<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> bty = <span class=\"code-snippet__string\">\"l\"<\/span>, #\u53ea\u753b\u5de6\u8fb9\u548c\u4e0b\u8fb9\u6846<\/span><\/code><code><span class=\"code-snippet_outer\"> xlim = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>),ylim= <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> xlab = <span class=\"code-snippet__string\">\"Nomogram-prediced OS (%)\"<\/span>,ylab = <span class=\"code-snippet__string\">\"Observed OS (%)\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#2166AC\"<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> cex.lab=<span class=\"code-snippet__number\">1.2<\/span>,cex.axis=<span class=\"code-snippet__number\">1<\/span>, cex.main=<span class=\"code-snippet__number\">1.2<\/span>, cex.sub=<span class=\"code-snippet__number\">0.6<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">lines(cal5[,<span class=\"code-snippet__built_in\">c<\/span>('mean.predicted',<span class=\"code-snippet__string\">\"KM\"<\/span>)],<\/span><\/code><code><span class=\"code-snippet_outer\"> type = 'b', lwd = <span class=\"code-snippet__number\">1<\/span>, col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#2166AC\"<\/span>), pch = <span class=\"code-snippet__number\">16<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">mtext(<span class=\"code-snippet__string\">\"\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">plot(cal8,lwd = <span class=\"code-snippet__number\">2<\/span>,lty = <span class=\"code-snippet__number\">0<\/span>,errbar.col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#B2182B\"<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> xlim = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>),ylim= <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>),col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#B2182B\"<\/span>),add = <span class=\"code-snippet__type\">T<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">lines(cal8[,<span class=\"code-snippet__built_in\">c<\/span>('mean.predicted',<span class=\"code-snippet__string\">\"KM\"<\/span>)],<\/span><\/code><code><span class=\"code-snippet_outer\"> type = 'b', lwd = <span class=\"code-snippet__number\">1<\/span>, col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#B2182B\"<\/span>), pch = <span class=\"code-snippet__number\">16<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">abline(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>, lwd = <span class=\"code-snippet__number\">2<\/span>, lty = <span class=\"code-snippet__number\">3<\/span>, col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#224444\"<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">legend(<span class=\"code-snippet__string\">\"topleft\"<\/span>, #\u56fe\u4f8b\u7684\u4f4d\u7f6e<\/span><\/code><code><span class=\"code-snippet_outer\"> legend = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"5-year\"<\/span>,<span class=\"code-snippet__string\">\"8-year\"<\/span>), #\u56fe\u4f8b\u6587\u5b57<\/span><\/code><code><span class=\"code-snippet_outer\"> col =<span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#2166AC\"<\/span>,<span class=\"code-snippet__string\">\"#B2182B\"<\/span>), #\u56fe\u4f8b\u7ebf\u7684\u989c\u8272\uff0c\u4e0e\u6587\u5b57\u5bf9\u5e94<\/span><\/code><code><span class=\"code-snippet_outer\"> lwd = <span class=\"code-snippet__number\">2<\/span>,#\u56fe\u4f8b\u4e2d\u7ebf\u7684\u7c97\u7ec6<\/span><\/code><code><span class=\"code-snippet_outer\"> cex = <span class=\"code-snippet__number\">1.2<\/span>,#\u56fe\u4f8b\u5b57\u4f53\u5927\u5c0f<\/span><\/code><code><span class=\"code-snippet_outer\"> bty = <span class=\"code-snippet__string\">\"n\"<\/span>)#\u4e0d\u663e\u793a\u56fe\u4f8b\u8fb9\u6846<\/span><\/code><code><span class=\"code-snippet_outer\">dev.off()<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.9878048780487805\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_cicXATLHdqRYfREdVhoMt1Up5uwIFg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyBMiaebYV0wRXKtNfxorecd7G5QnHIGL7pxibWIrtuyFrDicRHcicXATLHdqRYfREdVhoMt1Up5uwIFg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"492\" style=\"\" data-recalc-dims=\"1\" \/><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 10.5pt;text-align: justify;letter-spacing: 0.034em;\"><\/span><\/p>\n<p style=\"text-align: left;\"><strong><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 10.5pt;\">\u4eca\u5929\u5c0f\u679c\u5b8c\u6210\u4e86Nomogram\u6a21\u578b\u7684\u6784\u5efa\u548c\u9a8c\u8bc1\uff0c<\/span><\/span><span style=\"letter-spacing: 0.578px;text-align: left;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u6b22\u8fce\u5927\u5bb6\u6709\u95ee\u9898\u4e0e\u5c0f\u679c\u4e00\u8d77\u8ba8\u8bba\u54e6<\/span><\/strong><span style=\"letter-spacing: 0.578px;text-align: left;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\"><\/span><strong style=\"text-align: left;color: rgb(121, 123, 170);font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;outline: 0px;font-size: 15px;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);\"><\/strong><\/p>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: 0px;letter-spacing: 0.578px;text-align: left;white-space: normal;\">\n<section style=\"font-size: 16px;\">\n<section powered-by=\"xiumi.us\" style=\"margin: 10px;justify-content: flex-start;display: flex;flex-flow: row;\">\n<section style=\"padding-right: 10px;padding-left: 10px;display: inline-block;width: 558px;vertical-align: top;border-style: dashed;border-width: 1px;border-color: rgb(62, 62, 62);align-self: flex-start;flex: 0 0 auto;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;width: 536px;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(144, 215, 236);border-right-color: rgb(46, 172, 109);box-shadow: rgb(0, 0, 0) 0px 0px 0px;border-bottom-left-radius: 0px;\">\n<section powered-by=\"xiumi.us\" style=\"padding-right: 3px;padding-left: 3px;\">\n<section style=\"margin-top: 0.95em;margin-bottom: -0.65em;display: inline-block;width: 520px;vertical-align: top;\">\n<section style=\"width: 520px;\">\n<section style=\"border-top: 1px solid rgb(0, 0, 0);width: 519.479px;float: left;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<section style=\"margin-top: -3px;width: 6px;height: 6px;border-radius: 100%;float: right;background-color: rgb(46, 172, 109);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<section style=\"margin-top: -1em;padding: 3px 10px;display: inline-block;vertical-align: top;background-color: rgb(255, 255, 255);color: rgb(0, 154, 68);\">\n<p><strong>\u5f80\u671f\u63a8\u8350<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"text-align: justify;\">\n<section style=\"letter-spacing: 0.578px;line-height: 1.75em;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247491794&idx=1&sn=2b7a4de95169c79202e44813885a8250&chksm=cf7f7017f808f9015689839fe4057fd418bf7b20eb1dfb5a28cd92e56a41b5605e62bfbc16fb&scene=21#wechat_redirect\" textvalue=\"1.\u642d\u5efa\u751f\u4fe1\u5206\u6790\u6d41\u6c34\u7ebf\uff0c\u5982\u5de5\u5382\u4e00\u683724\u5c0f\u65f6\u8fd0\u8f6cSnakemake\u2014\u2014\u8fdb\u9636\u547d\u4ee4\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" style=\"font-size: 14px;\" rel=\"noopener\"><span style=\"font-size: 14px;\">1.\u642d\u5efa\u751f\u4fe1\u5206\u6790\u6d41\u6c34\u7ebf\uff0c\u5982\u5de5\u5382\u4e00\u683724\u5c0f\u65f6\u8fd0\u8f6cSnakemake\u2014\u2014\u8fdb\u9636\u547d\u4ee4<\/span><\/a><br \/><\/section>\n<section style=\"letter-spacing: 0.578px;line-height: 1.75em;\"><a target=\"_blank\" 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textvalue=\"3.\u5bf9\u5355\u7ec6\u80de\u5206\u6790\u6beb\u65e0\u5934\u7eea\uff1f\u8ba9popsicleR\u9886\u4f60\u5165\u95e8\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" style=\"font-size: 14px;\" rel=\"noopener\"><span style=\"font-size: 14px;\">3.\u5bf9\u5355\u7ec6\u80de\u5206\u6790\u6beb\u65e0\u5934\u7eea\uff1f\u8ba9popsicleR\u9886\u4f60\u5165\u95e8<\/span><\/a><\/section>\n<section style=\"letter-spacing: 0.578px;line-height: 1.75em;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247491905&idx=1&sn=fb34ebd6282962c7803badaee7a39096&chksm=cf7f7184f808f8929608c0050344ad86193d0fc6455c1c18e16cc17bf4b37832b63d3b18284e&scene=21#wechat_redirect\" textvalue=\"4.\u5c0f\u679c\u5e26\u4f60\u7ed8\u5236ROC\u66f2\u7ebf\u8bc4\u4f30\u751f\u5b58\u9884\u6d4b\u80fd\u529b\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\"><span 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href=\"https:\/\/mp.weixin.qq.com\/mp\/appmsgalbum?__biz=Mzg3OTg3MjQyNg==&action=getalbum&album_id=2664545260517294084#wechat_redirect\" title=\"\u751f\u4fe1\u5b9e\u64cd\" target=\"_blank\" rel=\"noopener\">#\u751f\u4fe1\u5b9e\u64cd<\/a><\/p>\n<\/div>\n<section data-mpa-powered-by=\"yiban.io\">\n<section powered-by=\"xiumi.us\">\n<section>\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section powered-by=\"xiumi.us\">\n<section>\n<section>\n<section powered-by=\"xiumi.us\">\n<section powered-by=\"xiumi.us\">\n<section>\n<p style=\"text-align: left;\"><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;letter-spacing: 0.034em;\">\u4eca\u5929\u5c0f\u679c\u4e3a\u5927\u5bb6\u5e26\u6765\u7684\u5206\u4eab\u5185\u5bb9\u4e3aNomogram\u6a21\u578b\u7684\u6784\u5efa\u548c\u9a8c\u8bc1\uff0c\u8be5\u5206\u6790\u5728\u80bf\u7624\u751f\u4fe1\u6587\u7ae0\u4e2d\u51fa\u73b0\u7684\u9891\u7387\u975e\u5e38\u9ad8\uff0c\u5c0f\u679c\u672c\u63a8\u6587\u4e2d\u4e3b\u8981\u7ed8\u5236\u4e86\u5217\u7ebf\u56fe\u548c\u6821\u6b63\u66f2\u7ebf\u7ed8\u5236\uff0c\u5e72\u8d27\u6ee1\u6ee1\uff0c\u975e\u5e38\u503c\u5f97\u5c0f\u4f19\u4f34\u5b66\u4e60\uff0c\u63a5\u4e0b\u6765\u8ddf\u7740\u5c0f\u679c\u9a6c\u4e0a\u5f00\u59cb\u4eca\u5929\u7684\u5b66\u4e60\uff01<\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;letter-spacing: 0.034em;\"><br \/><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\">\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;font-size: 16px;\" mpa-from-tpl=\"t\">\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;align-self: flex-end;flex: 0 0 auto;border-style: solid;border-width: 0px 0px 7px;border-bottom-color: rgb(175, 225, 255);min-width: 5%;height: auto;\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;font-size: 20px;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<p><strong mpa-from-tpl=\"t\" mpa-is-content=\"t\"><strong>1.<\/strong><strong>\u4f55\u4e3a<\/strong><strong>nomogram\u5206\u6790\uff1f<\/strong><\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 5%;flex: 0 0 auto;height: auto;align-self: flex-end;\" mpa-from-tpl=\"t\">\n<section style=\"transform: perspective(0px);transform-style: flat;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<section style=\"transform: translate3d(5px, 0px, 0px) rotateX(180deg);\" mpa-from-tpl=\"t\">\n<section style=\"display: inline-block;width: 6px;height: 6px;vertical-align: top;overflow: hidden;border-radius: 460px;background-color: rgb(244, 171, 189);\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<p><br mpa-from-tpl=\"t\" \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: left;\"><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;letter-spacing: 0.034em;text-align: justify;\">\u5728\u8fdb\u884c\u5206\u6790\u4e4b\u524d\uff0c\u5c0f\u679c\u5148\u4e3a\u5c0f\u4f19\u4f34\u4ecb\u7ecd\u4e00\u4e0bnomogram\u539f\u7406\uff0cnomogram\u5b9e\u8d28\u5c31\u662f\u56de\u5f52\u65b9\u7a0b\u7684\u53ef\u89c6\u5316\uff0c\u6839\u636e\u6240\u6709\u81ea\u53d8\u91cf\u56de\u5f52\u7cfb\u6570\u7684\u5927\u5c0f\u6765\u5236\u5b9a\u8bc4\u5206\u6807\u51c6\uff0c\u7ed9\u6bcf\u4e2a\u81ea\u53d8\u91cf\u7684\u6bcf\u79cd\u53d6\u503c\u6c34\u5e73\u4e00\u4e2a\u8bc4\u5206\uff0c\u5bf9\u6bcf\u4e2a\u6837\u672c\u5c31\u53ef\u8ba1\u7b97\u5f97\u5230\u4e00\u4e2a\u603b\u5206\uff0c\u518d\u901a\u8fc7\u5f97\u5206\u4e0e\u7ed3\u5c40\u53d1\u751f\u6982\u7387\u4e4b\u95f4\u7684\u8f6c\u6362\u51fd\u6570\u6765\u8ba1\u7b97\u6bcf\u4e2a\u6837\u672c\u7684\u7ed3\u5c40\u65f6\u95f4\u53d1\u751f\u7684\u6982\u7387\uff0c\u6211\u4eec\u901a\u8fc7Nomogram\u7684\u65b9\u6cd5\u5f97\u5230\u7684\u6982\u7387\u8bc4\u4ef7\u9884\u6d4b\u76ee\u6807\u72ec\u7acb\u751f\u5b58\u9884\u540e\u56e0\u7d20\u4e0e\u9884\u540e\u95f4\u7684\u76f8\u5173\u6027\u53ca\u5bf9\u751f\u5b58\u9884\u540e\u7684\u9884\u6d4b\u5173\u7cfb\u3002<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;letter-spacing: 0.034em;text-align: justify;\">\u4ee5\u4e0a\u5c31\u662f\u5c0f\u679c\u5bf9nomogram\u7684\u4ecb\u7ecd\uff0c\u5c0f\u4f19\u4f34\u4eec\u6709\u6ca1\u6709\u7406\u89e3\u5440\uff01<\/span><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;letter-spacing: 0.034em;text-align: justify;\">\u9a6c\u4e0a\u548c\u5c0f\u679c\u5f00\u542f\u5b9e\u64cd\u7ec3\u4e60\u5427\uff01<\/span><br \/><\/p>\n<p><span style=\"\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\"><em style=\"font-size: 15px;white-space: normal;color: rgb(178, 178, 178);letter-spacing: 0.578px;\"><span style=\"font-size: 13px;text-decoration: underline;\">\u516c\u4f17\u53f7\u540e\u53f0\u56de\u590d\u201c111″,\u9886\u53d6\u4ee3\u7801\uff0c\u4ee3\u7801\u7f16\u53f7\uff1a231005<\/span><\/em><\/span><\/p>\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\">\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;font-size: 16px;\" mpa-from-tpl=\"t\">\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;align-self: flex-end;flex: 0 0 auto;border-style: solid;border-width: 0px 0px 7px;border-bottom-color: rgb(175, 225, 255);min-width: 5%;height: auto;\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;font-size: 20px;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<p><strong mpa-from-tpl=\"t\" mpa-is-content=\"t\">2.\u51c6\u5907\u9700\u8981\u7684R\u5305<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 5%;flex: 0 0 auto;height: auto;align-self: flex-end;\" mpa-from-tpl=\"t\">\n<section style=\"transform: perspective(0px);transform-style: flat;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<section style=\"transform: translate3d(5px, 0px, 0px) rotateX(180deg);\" mpa-from-tpl=\"t\">\n<section style=\"display: inline-block;width: 6px;height: 6px;vertical-align: top;overflow: hidden;border-radius: 460px;background-color: rgb(244, 171, 189);\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<p><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;\"><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 20px;\"><\/span><\/p>\n<h2 style=\"text-align: center;\"><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\"><o:p><\/o:p><\/span><\/h2>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"sql\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u5b89\u88c5\u9700\u8981\u7684R\u5305<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">install.packages(<span class=\"code-snippet__string\">\"rms\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">install.packages(<span class=\"code-snippet__string\">\"survival\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u52a0\u8f7d\u9700\u8981\u7684R\u5305<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">library<\/span>(rms)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">library<\/span>(survival)<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.3888888888888889\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_IlmBAWe69EMUPMhNEgrv6NXX85lJxg-21.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAwyrj7kbUR3ULG9ZUbLrLkgibzL8qUpQROfe8ebc3gNSnu1dIlmBAWe69EMUPMhNEgrv6NXX85lJxg\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"1080\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\">\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;font-size: 16px;\" mpa-from-tpl=\"t\">\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;align-self: flex-end;flex: 0 0 auto;border-style: solid;border-width: 0px 0px 7px;border-bottom-color: rgb(175, 225, 255);min-width: 5%;height: auto;\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;font-size: 20px;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<p><strong mpa-from-tpl=\"t\" mpa-is-content=\"t\">3.\u8bfb\u53d6\u8f93\u5165\u6570\u636e<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 5%;flex: 0 0 auto;height: auto;align-self: flex-end;\" mpa-from-tpl=\"t\">\n<section style=\"transform: perspective(0px);transform-style: flat;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<section style=\"transform: translate3d(5px, 0px, 0px) rotateX(180deg);\" mpa-from-tpl=\"t\">\n<section style=\"display: inline-block;width: 6px;height: 6px;vertical-align: top;overflow: hidden;border-radius: 460px;background-color: rgb(244, 171, 189);\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<p><br mpa-from-tpl=\"t\" \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: left;font-size: 16px;\"><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;letter-spacing: 0.034em;text-align: justify;\">#\u884c\u540d\u4e3a\u6837\u672c\u540d\uff0c\u5217\u540d\u4e3a\u4e34\u5e8a\u56e0\u7d20<\/span><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\"><o:p><\/o:p><\/span><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"css\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__selector-tag\">pbc<\/span><<span class=\"code-snippet__selector-tag\">-read<\/span><span class=\"code-snippet__selector-class\">.table<\/span>(\"<span class=\"code-snippet__selector-tag\">Nomogram<\/span><span class=\"code-snippet__selector-class\">.txt<\/span>\")<\/span><\/code><\/pre>\n<\/section>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\"><\/span><span style=\"\"><o:p><\/o:p><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.2630057803468208\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_bpkmp7ZgNW0CKGVyvLAy7XFJzaqTww.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyBMiaebYV0wRXKtNfxorecdCl3Ixx7OEQURVkzfqaic6bUzmibpkmp7ZgNW0CKGVyvLAy7XFJzaqTww\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"692\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"php\"><code><span class=\"code-snippet_outer\">#\u5bf9bili\u5217\u8fdb\u884c\u6570\u636e\u5206\u5272<\/span><\/code><code><span class=\"code-snippet_outer\">pbc$catbili <- cut(pbc$bili,breaks=c(-Inf, 2, 4, Inf),<\/span><\/code><code><span class=\"code-snippet_outer\"> labels=c(\"low\",\"medium\",\"high\"))<\/span><\/code><code><span class=\"code-snippet_outer\">#\u589e\u52a0\u65b0\u7684\u5217<\/span><\/code><code><span class=\"code-snippet_outer\">pbc$died <- pbc$status==2<\/span><\/code><code><span class=\"code-snippet_outer\">4.Nomogram\u5206\u6790<\/span><\/code><code><span class=\"code-snippet_outer\">dd<-datadist(pbc)<\/span><\/code><code><span class=\"code-snippet_outer\">options(datadist=\"dd\")<\/span><\/code><code><span class=\"code-snippet_outer\">options(na.action=\"na.delete\")<\/span><\/code><code><span class=\"code-snippet_outer\">#\u591a\u56e0\u7d20cox\u56de\u5f52<\/span><\/code><code><span class=\"code-snippet_outer\">coxpbc<-cph(formula = Surv(time,died) ~ age + catbili + sex + copper + stage + trt ,data=pbc,x=T,y=T,surv = T,na.action=na.delete)<\/span><\/code><code><span class=\"code-snippet_outer\">surv<-Survival(coxpbc)<\/span><\/code><code><span class=\"code-snippet_outer\">#5\u5e74\u751f\u5b58\u7387<\/span><\/code><code><span class=\"code-snippet_outer\">surv3<-function(x) surv(1825,x)<\/span><\/code><code><span class=\"code-snippet_outer\">#8\u5e74\u751f\u5b58\u7387<\/span><\/code><code><span class=\"code-snippet_outer\">surv4<-function(x) surv(2920,x)<\/span><\/code><code><span class=\"code-snippet_outer\">x<-nomogram(coxpbc,fun = list(surv3,surv4),lp=T,<\/span><\/code><code><span class=\"code-snippet_outer\"> funlabel = c('5-year survival Probability','8-year survival Probability'),<\/span><\/code><code><span class=\"code-snippet_outer\"> maxscale = 100,fun.at = c(0.95,0.9,0.8,0.7,0.6,0.5,0.4,0.3,0.2,0.1))<\/span><\/code><code><span class=\"code-snippet_outer\">#\u7ed8\u5236\u5217\u7ebf\u56fe<\/span><\/code><code><span class=\"code-snippet_outer\">pdf(\"nomogram_classical.pdf\",width = 12,height = 10)<\/span><\/code><code><span class=\"code-snippet_outer\">plot(x, lplabel=\"Linear Predictor\",<\/span><\/code><code><span class=\"code-snippet_outer\"> xfrac=.35,varname.label=TRUE, varname.label.sep=\"=\", ia.space=.2, <\/span><\/code><code><span class=\"code-snippet_outer\"> tck=NA, tcl=-0.20, lmgp=0.3,<\/span><\/code><code><span class=\"code-snippet_outer\"> points.label='Points', total.points.label='Total Points',<\/span><\/code><code><span class=\"code-snippet_outer\"> total.sep.page=FALSE, <\/span><\/code><code><span class=\"code-snippet_outer\"> cap.labels=FALSE,cex.var = 1.6,cex.axis = 1.05,lwd=5,<\/span><\/code><code><span class=\"code-snippet_outer\"> label.every = 1,col.grid = gray(c(0.8, 0.95)))<\/span><\/code><code><span class=\"code-snippet_outer\">dev.off()<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.8294797687861272\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_yO2mNfx1oszReOqict1AUXXUW308Dg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyBMiaebYV0wRXKtNfxorecdlrL1xjE01YpJb7WbrFC2qxgDkyO2mNfx1oszReOqict1AUXXUW308Dg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"692\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\">\n<section data-mpa-template=\"t\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;font-size: 16px;\" mpa-from-tpl=\"t\">\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;align-self: flex-end;flex: 0 0 auto;border-style: solid;border-width: 0px 0px 7px;border-bottom-color: rgb(175, 225, 255);min-width: 5%;height: auto;\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;font-size: 20px;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<p><strong mpa-from-tpl=\"t\" mpa-is-content=\"t\">4.\u7ed8\u5236\u6821\u6b63\u66f2\u7ebf\u8fdb\u884c\u9a8c\u8bc1<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 5%;flex: 0 0 auto;height: auto;align-self: flex-end;\" mpa-from-tpl=\"t\">\n<section style=\"transform: perspective(0px);transform-style: flat;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<section style=\"transform: translate3d(5px, 0px, 0px) rotateX(180deg);\" mpa-from-tpl=\"t\">\n<section style=\"display: inline-block;width: 6px;height: 6px;vertical-align: top;overflow: hidden;border-radius: 460px;background-color: rgb(244, 171, 189);\" mpa-from-tpl=\"t\">\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\" mpa-from-tpl=\"t\">\n<p><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;font-size: 16px;\"><span style=\"font-size: 20px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><\/span><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"cs\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#5\u5e74\u751f\u5b58\u7387\u6821\u6b63\u66f2\u7ebf<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">f5<-cph(formula = Surv(time,died) ~ age + catbili + sex + copper +stage + trt,data=pbc,x=T,y=T,surv = T,na.action=na.delete,time.inc = <span class=\"code-snippet__number\">1825<\/span>) <\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__meta\">#\u53c2\u6570m=50\u8868\u793a\u6bcf\u7ec450\u4e2a\u6837\u672c\u8fdb\u884c\u91cd\u590d\u8ba1\u7b97<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">cal5<-calibrate(f5, cmethod=<span class=\"code-snippet__string\">\"KM\"<\/span>, method=<span class=\"code-snippet__string\">\"boot\"<\/span>,u=<span class=\"code-snippet__number\">1825<\/span>,m=<span class=\"code-snippet__number\">50<\/span>,B=<span class=\"code-snippet__number\">1000<\/span>) <\/span><\/code><code><span class=\"code-snippet_outer\">pdf(<span class=\"code-snippet__string\">\"calibration_5y.pdf\"<\/span>,width = <span class=\"code-snippet__number\">8<\/span>,height = <span class=\"code-snippet__number\">8<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">plot(cal5,<\/span><\/code><code><span class=\"code-snippet_outer\"> lwd = <span class=\"code-snippet__number\">2<\/span>,<span class=\"code-snippet__meta\">#<span class=\"code-snippet__meta-keyword\">error<\/span> bar\u7684\u7c97\u7ec6<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> lty = <span class=\"code-snippet__number\">2<\/span>,<span class=\"code-snippet__meta\">#<span class=\"code-snippet__meta-keyword\">error<\/span> bar\u7684\u7c7b\u578b\uff0c\u53ef\u4ee5\u662f0-6<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> errbar.col = c(<span class=\"code-snippet__string\">\"#2166AC\"<\/span>),<span class=\"code-snippet__meta\">#<span class=\"code-snippet__meta-keyword\">error<\/span> bar\u7684\u989c\u8272<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> xlim = c(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>),ylim= c(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> xlab = <span class=\"code-snippet__string\">\"Nomogram-prediced OS (%)\"<\/span>,ylab = <span class=\"code-snippet__string\">\"Observed OS (%)\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> cex.lab=<span class=\"code-snippet__number\">1.2<\/span>, cex.axis=<span class=\"code-snippet__number\">1<\/span>, cex.main=<span class=\"code-snippet__number\">1.2<\/span>, cex.sub=<span class=\"code-snippet__number\">0.6<\/span>) <span class=\"code-snippet__meta\">#\u5b57\u7684\u5927\u5c0f<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">lines(cal5[,c(<span class=\"code-snippet__string\">'mean.predicted'<\/span>,<span class=\"code-snippet__string\">\"KM\"<\/span>)], <\/span><\/code><code><span class=\"code-snippet_outer\"> type = <span class=\"code-snippet__string\">'b'<\/span>, <span class=\"code-snippet__meta\">#\u8fde\u7ebf\u7684\u7c7b\u578b\uff0c\u53ef\u4ee5\u662f\"p\",\"b\",\"o\"<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> lwd = <span class=\"code-snippet__number\">2<\/span>, <span class=\"code-snippet__meta\">#\u8fde\u7ebf\u7684\u7c97\u7ec6<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> pch = <span class=\"code-snippet__number\">16<\/span>, <span class=\"code-snippet__meta\">#\u70b9\u7684\u5f62\u72b6\uff0c\u53ef\u4ee5\u662f0-20<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> col = c(<span class=\"code-snippet__string\">\"#2166AC\"<\/span>)) <span class=\"code-snippet__meta\">#\u8fde\u7ebf\u7684\u989c\u8272<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">mtext(<span class=\"code-snippet__string\">\"\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">box(lwd = <span class=\"code-snippet__number\">1<\/span>) <span class=\"code-snippet__meta\">#\u8fb9\u6846\u7c97\u7ec6<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">abline(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>,lty = <span class=\"code-snippet__number\">3<\/span>, <span class=\"code-snippet__meta\">#\u5bf9\u89d2\u7ebf\u4e3a\u865a\u7ebf<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> lwd = <span class=\"code-snippet__number\">2<\/span>, <span class=\"code-snippet__meta\">#\u5bf9\u89d2\u7ebf\u7684\u7c97\u7ec6<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> col = c(<span class=\"code-snippet__string\">\"#224444\"<\/span>)<span class=\"code-snippet__meta\">#\u5bf9\u89d2\u7ebf\u7684\u989c\u8272<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"> ) <\/span><\/code><code><span class=\"code-snippet_outer\">dev.off()<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"1.004106776180698\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_nEicVvEeDsW4AjibzZLP3ZXva0Nw1Q.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyBMiaebYV0wRXKtNfxorecdblToBfyfS8fxJN4icicqSSd4AD5ibnEicVvEeDsW4AjibzZLP3ZXva0Nw1Q\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"487\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"swift\"><code><span class=\"code-snippet_outer\">#<span class=\"code-snippet__number\">8<\/span>\u5e74\u751f\u5b58\u7387\u6821\u6b63\u66f2\u7ebf,time.inc = <span class=\"code-snippet__number\">2920<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">f8<-cph(formula = <span class=\"code-snippet__type\">Surv<\/span>(time,died) ~ age + catbili + sex + copper +stage + trt,data=pbc,x=<span class=\"code-snippet__type\">T<\/span>,y=<span class=\"code-snippet__type\">T<\/span>,surv = <span class=\"code-snippet__type\">T<\/span>,na.action=na.delete,time.inc = <span class=\"code-snippet__number\">2920<\/span>) <\/span><\/code><code><span class=\"code-snippet_outer\">cal8<-calibrate(f8, cmethod=<span class=\"code-snippet__string\">\"KM\"<\/span>, method=<span class=\"code-snippet__string\">\"boot\"<\/span>,u=<span class=\"code-snippet__number\">2920<\/span>,m=<span class=\"code-snippet__number\">50<\/span>,<span class=\"code-snippet__type\">B<\/span>=<span class=\"code-snippet__number\">1000<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">pdf(<span class=\"code-snippet__string\">\"calibration_8y.pdf\"<\/span>,width = <span class=\"code-snippet__number\">8<\/span>,height = <span class=\"code-snippet__number\">8<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">plot(cal8,<\/span><\/code><code><span class=\"code-snippet_outer\"> lwd = <span class=\"code-snippet__number\">2<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> lty = <span class=\"code-snippet__number\">4<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> errbar.col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#B2182B\"<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> xlim = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>),ylim= <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> xlab = <span class=\"code-snippet__string\">\"Nomogram-prediced OS (%)\"<\/span>,ylab = <span class=\"code-snippet__string\">\"Observed OS (%)\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#B2182B\"<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> cex.lab=<span class=\"code-snippet__number\">1.2<\/span>,cex.axis=<span class=\"code-snippet__number\">1<\/span>, cex.main=<span class=\"code-snippet__number\">1.2<\/span>, cex.sub=<span class=\"code-snippet__number\">0.6<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">lines(cal8[,<span class=\"code-snippet__built_in\">c<\/span>('mean.predicted',<span class=\"code-snippet__string\">\"KM\"<\/span>)],<\/span><\/code><code><span class=\"code-snippet_outer\"> type= 'b',<\/span><\/code><code><span class=\"code-snippet_outer\"> lwd = <span class=\"code-snippet__number\">2<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#B2182B\"<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> pch = <span class=\"code-snippet__number\">16<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">mtext(<span class=\"code-snippet__string\">\"\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">box(lwd = <span class=\"code-snippet__number\">1<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">abline(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>,lty= <span class=\"code-snippet__number\">3<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> lwd = <span class=\"code-snippet__number\">2<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> col =<span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#224444\"<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\">dev.off()<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"1\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_rSLq2TXfiaj8O3uyrEWpEGwiaZ1cpg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyBMiaebYV0wRXKtNfxorecd1zHo92RnpCFsiba6pzjMCTeFfgerSLq2TXfiaj8O3uyrEWpEGwiaZ1cpg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"645\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"swift\"><code><span class=\"code-snippet_outer\">#\u7ed8\u5236<span class=\"code-snippet__number\">5<\/span>\u5e74\u548c<span class=\"code-snippet__number\">8<\/span>\u5e74\u751f\u5b58\u7387\u6821\u6b63\u66f2\u7ebf<\/span><\/code><code><span class=\"code-snippet_outer\">pdf(<span class=\"code-snippet__string\">\"calibration_compare.pdf\"<\/span>,width = <span class=\"code-snippet__number\">8<\/span>,height = <span class=\"code-snippet__number\">8<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">plot(cal5,lwd = <span class=\"code-snippet__number\">2<\/span>,lty = <span class=\"code-snippet__number\">0<\/span>,errbar.col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#2166AC\"<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> bty = <span class=\"code-snippet__string\">\"l\"<\/span>, #\u53ea\u753b\u5de6\u8fb9\u548c\u4e0b\u8fb9\u6846<\/span><\/code><code><span class=\"code-snippet_outer\"> xlim = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>),ylim= <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> xlab = <span class=\"code-snippet__string\">\"Nomogram-prediced OS (%)\"<\/span>,ylab = <span class=\"code-snippet__string\">\"Observed OS (%)\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#2166AC\"<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> cex.lab=<span class=\"code-snippet__number\">1.2<\/span>,cex.axis=<span class=\"code-snippet__number\">1<\/span>, cex.main=<span class=\"code-snippet__number\">1.2<\/span>, cex.sub=<span class=\"code-snippet__number\">0.6<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">lines(cal5[,<span class=\"code-snippet__built_in\">c<\/span>('mean.predicted',<span class=\"code-snippet__string\">\"KM\"<\/span>)],<\/span><\/code><code><span class=\"code-snippet_outer\"> type = 'b', lwd = <span class=\"code-snippet__number\">1<\/span>, col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#2166AC\"<\/span>), pch = <span class=\"code-snippet__number\">16<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">mtext(<span class=\"code-snippet__string\">\"\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">plot(cal8,lwd = <span class=\"code-snippet__number\">2<\/span>,lty = <span class=\"code-snippet__number\">0<\/span>,errbar.col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#B2182B\"<\/span>),<\/span><\/code><code><span class=\"code-snippet_outer\"> xlim = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>),ylim= <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>),col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#B2182B\"<\/span>),add = <span class=\"code-snippet__type\">T<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">lines(cal8[,<span class=\"code-snippet__built_in\">c<\/span>('mean.predicted',<span class=\"code-snippet__string\">\"KM\"<\/span>)],<\/span><\/code><code><span class=\"code-snippet_outer\"> type = 'b', lwd = <span class=\"code-snippet__number\">1<\/span>, col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#B2182B\"<\/span>), pch = <span class=\"code-snippet__number\">16<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">abline(<span class=\"code-snippet__number\">0<\/span>,<span class=\"code-snippet__number\">1<\/span>, lwd = <span class=\"code-snippet__number\">2<\/span>, lty = <span class=\"code-snippet__number\">3<\/span>, col = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#224444\"<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">legend(<span class=\"code-snippet__string\">\"topleft\"<\/span>, #\u56fe\u4f8b\u7684\u4f4d\u7f6e<\/span><\/code><code><span class=\"code-snippet_outer\"> legend = <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"5-year\"<\/span>,<span class=\"code-snippet__string\">\"8-year\"<\/span>), #\u56fe\u4f8b\u6587\u5b57<\/span><\/code><code><span class=\"code-snippet_outer\"> col =<span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"#2166AC\"<\/span>,<span class=\"code-snippet__string\">\"#B2182B\"<\/span>), #\u56fe\u4f8b\u7ebf\u7684\u989c\u8272\uff0c\u4e0e\u6587\u5b57\u5bf9\u5e94<\/span><\/code><code><span class=\"code-snippet_outer\"> lwd = <span class=\"code-snippet__number\">2<\/span>,#\u56fe\u4f8b\u4e2d\u7ebf\u7684\u7c97\u7ec6<\/span><\/code><code><span class=\"code-snippet_outer\"> cex = <span class=\"code-snippet__number\">1.2<\/span>,#\u56fe\u4f8b\u5b57\u4f53\u5927\u5c0f<\/span><\/code><code><span class=\"code-snippet_outer\"> bty = <span class=\"code-snippet__string\">\"n\"<\/span>)#\u4e0d\u663e\u793a\u56fe\u4f8b\u8fb9\u6846<\/span><\/code><code><span class=\"code-snippet_outer\">dev.off()<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.9878048780487805\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_cicXATLHdqRYfREdVhoMt1Up5uwIFg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyBMiaebYV0wRXKtNfxorecd7G5QnHIGL7pxibWIrtuyFrDicRHcicXATLHdqRYfREdVhoMt1Up5uwIFg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"492\" style=\"\" data-recalc-dims=\"1\" \/><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 10.5pt;text-align: justify;letter-spacing: 0.034em;\"><\/span><\/p>\n<p style=\"text-align: left;\"><strong><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 10.5pt;\">\u4eca\u5929\u5c0f\u679c\u5b8c\u6210\u4e86Nomogram\u6a21\u578b\u7684\u6784\u5efa\u548c\u9a8c\u8bc1\uff0c<\/span><\/span><span style=\"letter-spacing: 0.578px;text-align: left;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u6b22\u8fce\u5927\u5bb6\u6709\u95ee\u9898\u4e0e\u5c0f\u679c\u4e00\u8d77\u8ba8\u8bba\u54e6<\/span><\/strong><span style=\"letter-spacing: 0.578px;text-align: left;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\"><\/span><strong style=\"text-align: left;color: rgb(121, 123, 170);font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;outline: 0px;font-size: 15px;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);\"><\/strong><\/p>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: 0px;letter-spacing: 0.578px;text-align: left;white-space: normal;\">\n<section style=\"font-size: 16px;\">\n<section powered-by=\"xiumi.us\" style=\"margin: 10px;justify-content: flex-start;display: flex;flex-flow: row;\">\n<section style=\"padding-right: 10px;padding-left: 10px;display: inline-block;width: 558px;vertical-align: top;border-style: dashed;border-width: 1px;border-color: rgb(62, 62, 62);align-self: flex-start;flex: 0 0 auto;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;width: 536px;border-width: 0px 0px 0px 10px;border-style: solid;border-left-color: rgb(144, 215, 236);border-right-color: rgb(46, 172, 109);box-shadow: rgb(0, 0, 0) 0px 0px 0px;border-bottom-left-radius: 0px;\">\n<section powered-by=\"xiumi.us\" style=\"padding-right: 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0.578px;line-height: 1.75em;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247491794&idx=1&sn=2b7a4de95169c79202e44813885a8250&chksm=cf7f7017f808f9015689839fe4057fd418bf7b20eb1dfb5a28cd92e56a41b5605e62bfbc16fb&scene=21#wechat_redirect\" textvalue=\"1.\u642d\u5efa\u751f\u4fe1\u5206\u6790\u6d41\u6c34\u7ebf\uff0c\u5982\u5de5\u5382\u4e00\u683724\u5c0f\u65f6\u8fd0\u8f6cSnakemake\u2014\u2014\u8fdb\u9636\u547d\u4ee4\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" style=\"font-size: 14px;\" rel=\"noopener\"><span style=\"font-size: 14px;\">1.\u642d\u5efa\u751f\u4fe1\u5206\u6790\u6d41\u6c34\u7ebf\uff0c\u5982\u5de5\u5382\u4e00\u683724\u5c0f\u65f6\u8fd0\u8f6cSnakemake\u2014\u2014\u8fdb\u9636\u547d\u4ee4<\/span><\/a><br \/><\/section>\n<section style=\"letter-spacing: 0.578px;line-height: 1.75em;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247491705&idx=1&sn=9ff9b6da28b3a256a99c6697d589be66&chksm=cf7f70bcf808f9aafd1019a0bba3dd3a55e2867dbb9a09203f13c2683adf867094637c405ed1&scene=21#wechat_redirect\" textvalue=\"2.\u6bd4blast\u8fd8\u4f18\u79c0\u7684\u5e8f\u5217\u6bd4\u5bf9\u5de5\u5177\uff1fHMMER\u6765\u4e86\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" style=\"font-size: 14px;\" rel=\"noopener\"><span style=\"font-size: 14px;\">2.\u6bd4blast\u8fd8\u4f18\u79c0\u7684\u5e8f\u5217\u6bd4\u5bf9\u5de5\u5177\uff1fHMMER\u6765\u4e86<\/span><\/a><\/section>\n<section style=\"letter-spacing: 0.578px;line-height: 1.75em;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247491909&idx=1&sn=902e34bcf53e605fba2b457ec6a33e36&chksm=cf7f7180f808f8961542f458a49da14e85d8831449fb65fbf2623d55affc564686a5422f56fd&scene=21#wechat_redirect\" textvalue=\"3.\u5bf9\u5355\u7ec6\u80de\u5206\u6790\u6beb\u65e0\u5934\u7eea\uff1f\u8ba9popsicleR\u9886\u4f60\u5165\u95e8\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" style=\"font-size: 14px;\" rel=\"noopener\"><span style=\"font-size: 14px;\">3.\u5bf9\u5355\u7ec6\u80de\u5206\u6790\u6beb\u65e0\u5934\u7eea\uff1f\u8ba9popsicleR\u9886\u4f60\u5165\u95e8<\/span><\/a><\/section>\n<section style=\"letter-spacing: 0.578px;line-height: 1.75em;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247491905&idx=1&sn=fb34ebd6282962c7803badaee7a39096&chksm=cf7f7184f808f8929608c0050344ad86193d0fc6455c1c18e16cc17bf4b37832b63d3b18284e&scene=21#wechat_redirect\" textvalue=\"4.\u5c0f\u679c\u5e26\u4f60\u7ed8\u5236ROC\u66f2\u7ebf\u8bc4\u4f30\u751f\u5b58\u9884\u6d4b\u80fd\u529b\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\"><span style=\"font-size: 14px;\">4.\u5c0f\u679c\u5e26\u4f60\u7ed8\u5236ROC\u66f2\u7ebf\u8bc4\u4f30\u751f\u5b58\u9884\u6d4b\u80fd\u529b<\/span><\/a><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247493783&idx=2&sn=ca61bdc99aa7cec4b8aabadc76f1bee0&chksm=cf7f7852f808f144c0e952f7b0f7b9c1a9000fbcd44670f81658f4a7079a6ad3e1a8356e1928&scene=21#wechat_redirect\" textvalue=\"\u4f60\u5df2\u9009\u4e2d\u4e86\u6dfb\u52a0\u94fe\u63a5\u7684\u5185\u5bb9\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"1\" rel=\"noopener\"><span class=\"js_jump_icon h5_image_link\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.4255555555555556\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_3enDMf2LD6pjia3zQolKXIfTwuh6AA-5.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAxweqRKIWbRUBSWSGID9aog3q3QVgsHZplb1JyboXh8CPz6b3enDMf2LD6pjia3zQolKXIfTwuh6AA\/640?wx_fmt=jpeg&wxfrom=5&wx_lazy=1&wx_co=1'\" data-w=\"900\" data-recalc-dims=\"1\" \/><\/span><\/a><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.3888888888888889\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_SibFRUHIk0cCbShYgOsGDPrxeHkEtw-1.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAwyrj7kbUR3ULG9ZUbLrLkgvrEB1jg0GibYczZiaOORjzpxpIjSibFRUHIk0cCbShYgOsGDPrxeHkEtw\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"1080\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"display: none;\"><mp-style-type data-value=\"3\"><\/mp-style-type><\/p>\n<p><\/content>\n<\/div>\n<p><\/body><br \/>\n<\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u9ad8\u5206\u751f\u4fe1\u6587\u7ae0\u5fc5\u5907\u5206\u6790\u5185\u5bb9-Nomogram\u6a21\u578b\u7684\u6784\u5efa\u548c\u9a8c\u8bc1 \u539f\u521b \u5c0f\u679c &nb […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/58515"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=58515"}],"version-history":[{"count":1,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/58515\/revisions"}],"predecessor-version":[{"id":58524,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/58515\/revisions\/58524"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=58515"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=58515"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=58515"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}