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10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p><strong>2.\u51c6\u5907\u9700\u8981\u7684R\u5305<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3cHFo8Iq1AbTyWoMEa9rUQibFxpnh1QKibOdmGxWuusAPTklVancTyTRA\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u5b89\u88c5\u9700\u8981\u7684R\u5305<\/span><\/code><code><span class=\"code-snippet_outer\">install.packages(<span class=\"code-snippet__string\">\"survival\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">#\u52a0\u8f7d\u9700\u8981\u7684R\u5305<\/span><\/code><code><span class=\"code-snippet_outer\">library(survival)<\/span><\/code><code><span class=\"code-snippet_outer\">library(ggDCA)<\/span><\/code><code><span class=\"code-snippet_outer\">library(tidyverse)<\/span><\/code><code><span class=\"code-snippet_outer\">source(<span class=\"code-snippet__string\">\"stdca.R\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3mJ85xYxsPVTFjPZt5CLmpjOFKoAJicpHa1CWfsOPTSiaXQlp500dd0ug\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p><strong>3.\u8bfb\u53d6\u8f93\u5165\u6570\u636e<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3cHFo8Iq1AbTyWoMEa9rUQibFxpnh1QKibOdmGxWuusAPTklVancTyTRA\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u884c\u540d\u4e3a\u6837\u672c\u540d\uff0c\u5176\u4ed6\u5217\u4e3a\u4e34\u5e8a\u56e0\u7d20\uff0c\u4e3b\u8981\u5305\u62ec\u751f\u5b58\u65f6\u95f4\uff0c\u751f\u5b58\u72b6\u6001\u7b49\u4fe1\u606f\u3002<\/span><\/code><code><span class=\"code-snippet_outer\">pbc<-read.table(<span class=\"code-snippet__string\">\"easy_input.txt\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.31296296296296294\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_ic9iaZlRv2VBjKD4ibicIJ961NhtRQ.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3d51Skic9LGPRCUDTjEPYXXD9aLEo5ic9iaZlRv2VBjKD4ibicIJ961NhtRQ\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u5220\u6389\u7f3a\u5931\u6570\u636e<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">pbc <- na.omit(pbc)<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">#\u5148\u628abili\u5206\u4e3a\u4e09\u7c7b\uff1a\u4f4e\u3001\u4e2d\u3001\u9ad8<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">pbc$catbili <- cut(pbc$bili,breaks=c(-Inf, <span class=\"code-snippet__number\">2<\/span>, <span class=\"code-snippet__number\">4<\/span>, Inf),<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"> labels=c(<span class=\"code-snippet__string\">\"low\"<\/span>,<span class=\"code-snippet__string\">\"medium\"<\/span>,<span class=\"code-snippet__string\">\"high\"<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"> <\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">#\u628astatus\u5206\u4e3a\u4e24\u7c7b\uff0c\u539f\u6765\u7684<span class=\"code-snippet__number\">2<\/span>\u4e3a\u53d8\u6210<span class=\"code-snippet__number\">1<\/span>\uff0c\u539f\u6765\u7684<span class=\"code-snippet__number\">1<\/span>\u548c<span class=\"code-snippet__number\">0<\/span>\u53d8\u6210<span class=\"code-snippet__number\">0<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">pbc$died <- pbc$status==<span class=\"code-snippet__number\">2<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">pbc$status =ifelse(pbc$died==<span class=\"code-snippet__string\">\"TRUE\"<\/span>,<span class=\"code-snippet__number\">1<\/span>,<span class=\"code-snippet__number\">0<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3mJ85xYxsPVTFjPZt5CLmpjOFKoAJicpHa1CWfsOPTSiaXQlp500dd0ug\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p><strong>4.DCA\u5206\u6790\u8bc4\u4ef7\u6a21\u578b\u7684\u4e34\u5e8a\u51c0\u83b7\u76ca\u7387<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3cHFo8Iq1AbTyWoMEa9rUQibFxpnh1QKibOdmGxWuusAPTklVancTyTRA\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u591a\u56e0\u7d20\u56de\u5f52\u5206\u6790<\/span><\/code><code><span class=\"code-snippet_outer\">Srv = Surv(pbc$time, pbc$died)<\/span><\/code><code><span class=\"code-snippet_outer\">#\u6b64\u5904\u9009\u62e9<span class=\"code-snippet__number\">5<\/span>\u5e74\u7684\u65f6\u95f4\u8282\u70b9\uff0c\u8f93\u5165\u6587\u4ef6\u7684time\u5217\u7684\u5355\u4f4d\u662f\u5929\uff0c<span class=\"code-snippet__number\">5<\/span>\u5e74\u662f<span class=\"code-snippet__number\">1825<\/span>\u5929\u3002<\/span><\/code><code><span class=\"code-snippet_outer\">#\u4e0b\u9762\u6bcf\u4e24\u884c\u8ba1\u7b97<span class=\"code-snippet__number\">1<\/span>\u79cdcox\u6a21\u578b\u7684\u7cfb\u6570\uff0c\u540e\u9762\u5c06\u753b\u56fe\u5bf9\u6bd4<\/span><\/code><\/pre>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u6a21\u578b\u4e00<\/span><\/code><code><span class=\"code-snippet_outer\">coxmod1 = coxph(Srv ~ trt + age + sex + hepato + catbili + copper + stage, data=pbc)<\/span><\/code><code><span class=\"code-snippet_outer\">pbc$model1 = c(<span class=\"code-snippet__number\">1<\/span> - (summary(survfit(coxmod1,newdata=pbc), times=<span class=\"code-snippet__number\">1825<\/span>)$surv))<\/span><\/code><\/pre>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u6a21\u578b\u4e8c<\/span><\/code><code><span class=\"code-snippet_outer\">coxmod2 = coxph(Srv ~ ascites + spiders + edema + chol + albumin + alk.phos + ast + trig + platelet + protime, data=pbc)<\/span><\/code><code><span class=\"code-snippet_outer\">pbc$model2 = c(<span class=\"code-snippet__number\">1<\/span> - (summary(survfit(coxmod2,newdata=pbc), times=<span class=\"code-snippet__number\">1825<\/span>)$surv))<\/span><\/code><\/pre>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u6a21\u578b\u4e09<\/span><\/code><code><span class=\"code-snippet_outer\">coxmod3 = coxph(Srv ~ trt + age + sex + hepato + catbili + copper + stage + ascites + spiders + edema + chol + albumin + alk.phos + ast + trig + platelet + protime, data=pbc)<\/span><\/code><code><span class=\"code-snippet_outer\">pbc$model3 = c(<span class=\"code-snippet__number\">1<\/span> - (summary(survfit(coxmod3,newdata=pbc), times=<span class=\"code-snippet__number\">1825<\/span>)$surv))<\/span><\/code><\/pre>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u6a21\u578b\u56db<\/span><\/code><code><span class=\"code-snippet_outer\">coxmod4 = coxph(Srv ~ stage, data=pbc)<\/span><\/code><code><span class=\"code-snippet_outer\">pbc$model4 = c(<span class=\"code-snippet__number\">1<\/span> - (summary(survfit(coxmod4,newdata=pbc), times=<span class=\"code-snippet__number\">1825<\/span>)$surv))<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.4009259259259259\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_MSWRp2ALhYU5yAHGuLfzJ4dZsjyr9g.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3AICTaMkR0Lr8ToNjiaoL9GRiaIMSWRp2ALhYU5yAHGuLfzJ4dZsjyr9g\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u753b\u4e00\u6761\u4e34\u5e8a\u51c0\u83b7\u76ca\u7387<\/span><\/code><code><span class=\"code-snippet_outer\">mod1<-stdca(data=pbc, outcome=<span class=\"code-snippet__string\">\"status\"<\/span>, ttoutcome=<span class=\"code-snippet__string\">\"time\"<\/span>, timepoint=<span class=\"code-snippet__number\">1825<\/span>, <\/span><\/code><code><span class=\"code-snippet_outer\"> predictors=<span class=\"code-snippet__string\">\"model1\"<\/span>,cmprsk=TRUE,smooth=TRUE, xstop=<span class=\"code-snippet__number\">0.5<\/span>,intervention=<span class=\"code-snippet__string\">\"FALSE\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.9852507374631269\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_gevCTTzeGd8ugojBXCpItfNO9WKMSA.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t33xvqUCXPkNaLm7JplbtaYUWMgevCTTzeGd8ugojBXCpItfNO9WKMSA\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"678\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u591a\u4e2a\u6a21\u578b\u6bd4\u8f83<\/span><\/code><code><span class=\"code-snippet_outer\">pdf(<span class=\"code-snippet__string\">\"net_benefit.pdf\"<\/span>,width = <span class=\"code-snippet__number\">6<\/span>,height = <span class=\"code-snippet__number\">6<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">stdca(data=pbc, outcome=<span class=\"code-snippet__string\">\"status\"<\/span>, ttoutcome=<span class=\"code-snippet__string\">\"time\"<\/span>, timepoint=<span class=\"code-snippet__number\">1825<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> predictors=c(<span class=\"code-snippet__string\">\"model1\"<\/span>,<span class=\"code-snippet__string\">\"model2\"<\/span>,<span class=\"code-snippet__string\">\"model3\"<\/span>,<span class=\"code-snippet__string\">\"model4\"<\/span>), <\/span><\/code><code><span class=\"code-snippet_outer\"> cmprsk=TRUE, smooth=TRUE, <\/span><\/code><code><span class=\"code-snippet_outer\"> xstop=<span class=\"code-snippet__number\">0.5<\/span>,intervention=<span class=\"code-snippet__string\">\"FALSE\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">dev.off()<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"1.0013812154696133\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_aFty4bfnQFlT216uRal82GFzYkUXwA.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3NQDHdyqsXMk9ia7mjhlzxuG1FiaFty4bfnQFlT216uRal82GFzYkUXwA\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"724\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3mJ85xYxsPVTFjPZt5CLmpjOFKoAJicpHa1CWfsOPTSiaXQlp500dd0ug\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p><strong>5.DCA\u5206\u6790\u8bc4\u4ef7\u6a21\u578b\u7684\u5e72\u9884\u4e34\u5e8a\u51c0\u83b7\u76ca\u7387<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3cHFo8Iq1AbTyWoMEa9rUQibFxpnh1QKibOdmGxWuusAPTklVancTyTRA\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u753b\u4e00\u6761\u5e72\u9884\u4e34\u5e8a\u51c0\u83b7\u76ca\u7387<\/span><\/code><code><span class=\"code-snippet_outer\">pdf(<span class=\"code-snippet__string\">\"3red.pdf\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">mod1 <- stdca(data=pbc, outcome=<span class=\"code-snippet__string\">\"status\"<\/span>, ttoutcome=<span class=\"code-snippet__string\">\"time\"<\/span>, timepoint=<span class=\"code-snippet__number\">1825<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> predictors=<span class=\"code-snippet__string\">\"model1\"<\/span>,cmprsk=TRUE,smooth=TRUE, xstop=<span class=\"code-snippet__number\">0.5<\/span>,intervention=<span class=\"code-snippet__string\">\"TRUE\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">dev.off()<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.9940828402366864\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_Px9FEKcp5HEumiacd7ibPPLwAtfeKw.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3SwiafuNgib8m1Ud2wDr1jQfS7t2jPx9FEKcp5HEumiacd7ibPPLwAtfeKw\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"676\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u591a\u6761\u6bd4\u5bf9<\/span><\/code><code><span class=\"code-snippet_outer\">pdf(<span class=\"code-snippet__string\">\"net_reduction.pdf\"<\/span>,width = <span class=\"code-snippet__number\">6<\/span>,height = <span class=\"code-snippet__number\">6<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">stdca(data=pbc, outcome=<span class=\"code-snippet__string\">\"status\"<\/span>, ttoutcome=<span class=\"code-snippet__string\">\"time\"<\/span>, timepoint=<span class=\"code-snippet__number\">1825<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> predictors=c(<span class=\"code-snippet__string\">\"model1\"<\/span>,<span class=\"code-snippet__string\">\"model2\"<\/span>,<span class=\"code-snippet__string\">\"model3\"<\/span>,<span class=\"code-snippet__string\">\"model4\"<\/span>), <\/span><\/code><code><span class=\"code-snippet_outer\"> cmprsk=TRUE, smooth=TRUE, <\/span><\/code><code><span class=\"code-snippet_outer\"> xstop=<span class=\"code-snippet__number\">0.5<\/span>,intervention=<span class=\"code-snippet__string\">\"TRUE\"<\/span>) <\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"1.0069204152249136\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_mtQK7EFfmkLkiaIhXXLcoaq6fVm42w.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3ayOwrWzXUoyC3tGKHVvdmt6yBmtQK7EFfmkLkiaIhXXLcoaq6fVm42w\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"578\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3mJ85xYxsPVTFjPZt5CLmpjOFKoAJicpHa1CWfsOPTSiaXQlp500dd0ug\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p><strong>6.ggDCA\u5305\u7ed8\u5236DCA\u66f2\u7ebf<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3cHFo8Iq1AbTyWoMEa9rUQibFxpnh1QKibOdmGxWuusAPTklVancTyTRA\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u6784\u5efa\u4e24\u4e2a\u6a21\u578b<\/span><\/code><code><span class=\"code-snippet_outer\">fit1 <- coxph(Surv(time,status)~age,data = pbc)<\/span><\/code><code><span class=\"code-snippet_outer\">fit2 <- coxph(Surv(time,status)~trt + age + sex + hepato + catbili + copper + stage,data = pbc)<\/span><\/code><code><span class=\"code-snippet_outer\">#\u7ed8\u5236\u5355\u4e2a\u6a21\u578b\u7684DCA\u66f2\u7ebf<\/span><\/code><code><span class=\"code-snippet_outer\">plot1 <- dca(fit1,times = <span class=\"code-snippet__number\">365<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">ggplot(plot1)<\/span><\/code><code><span class=\"code-snippet_outer\">ggsave(<span class=\"code-snippet__string\">\"dca1.pdf\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.9985272459499264\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_339d21RvMLibiaSfI3OiaRYAtUWI6A.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t36c9cEvG5VMdDnhZtuQ3jaDpTC4ia339d21RvMLibiaSfI3OiaRYAtUWI6A\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"679\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u7ed8\u5236\u4e24\u4e2a\u6a21\u578b\u7684DCA\u66f2\u7ebf<\/span><\/code><code><span class=\"code-snippet_outer\">plot2 <- dca(fit1,fit2,times = <span class=\"code-snippet__number\">365<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">ggplot(plot2)<\/span><\/code><code><span class=\"code-snippet_outer\">ggsave(<span class=\"code-snippet__string\">\"dca2.pdf\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.9955686853766618\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_u31kRZu9yKnesyxgxHZNpARX68knQg.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3wTrMTO6n5bhcRgiaicBphbg2Q7u31kRZu9yKnesyxgxHZNpARX68knQg\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"677\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: 0px;font-size: 16px;letter-spacing: 0.578px;white-space: normal;\">\n<p><br \/><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: 10px;font-size: 16px;letter-spacing: 0.578px;white-space: normal;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\">\n<section style=\"padding: 7px;display: inline-block;width: 578px;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(176, 176, 176);\">\n<section powered-by=\"xiumi.us\" style=\"justify-content: flex-start;display: flex;flex-flow: row;\">\n<section style=\"padding: 18px;display: inline-block;width: 562px;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgba(249, 238, 237, 0.5);\">\n<section powered-by=\"xiumi.us\">\n<section style=\"text-align: justify;font-size: 14px;\">\n<p>PCA\u5206\u6790\u76f8\u5173\u5176\u4ed6\u5206\u6790\u5185\u5bb9\u6b22\u8fce\u5c1d\u8bd5\u672c\u516c\u53f8\u65b0\u5f00\u53d1\u7684\u4e91\u5e73\u53f0\u751f\u7269\u4fe1\u606f\u5206\u6790\u5c0f\u5de5\u5177\uff0c\u96f6\u4ee3\u7801\u5b8c\u6210\u5206\u6790\uff0c\u4e91\u5e73\u53f0\u7f51\u5740\uff1a<\/p>\n<p>http:\/\/www.biocloudservice.com\/home.html<\/p>\n<p><br \/><\/p>\n<p>\u6b22\u8fce\u4f7f\u7528\uff1a\u4e91\u751f\u4fe1\u5e73\u53f0 ( http:\/\/www.biocloudservice.com\/home.html)<\/p>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: -65px;margin-bottom: -65px;transform: scale(0.5);transform-origin: center center;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;text-align: center;line-height: 0;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"1\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_wYiaRVicQ7mFIFaSUHvkTFD7OibrBQ.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3ZPicSu6dicMQGZRtowOTS7EicCsJwvwYiaRVicQ7mFIFaSUHvkTFD7OibrBQ\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"258\" style=\"vertical-align: middle;width: 258px;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;font-size: 16px;letter-spacing: 0.578px;white-space: normal;min-height: 40px;\">\n<section style=\"margin-right: auto;margin-bottom: -10px;margin-left: auto;width: 578px;\">\n<table width=\"100%\">\n<tbody>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:43.classicTable1:0\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:43.classicTable1:0.td@@0\" width=\"96.3700%\" style=\"padding: 10px 0px;border-style: none;border-color: rgb(62, 62, 62);background-color: rgb(249, 174, 165);\">\n<section powered-by=\"xiumi.us\" style=\"line-height: 1;text-align: center;font-size: 17px;color: rgb(255, 255, 255);letter-spacing: 5px;\">\n<p><strong>\u5f80\u671f\u63a8\u8350<\/strong><\/p>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:43.classicTable1:1\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:43.classicTable1:1.td@@0\" width=\"96.3700%\" style=\"padding-right: 5px;padding-left: 5px;border-top: 0px none rgb(62, 62, 62);border-right: 0px none rgb(62, 62, 62);border-left: 0px none rgb(62, 62, 62);border-bottom-style: dashed;border-bottom-color: rgb(202, 198, 198);background-color: rgb(247, 247, 247);\">\n<section powered-by=\"xiumi.us\" style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;\">\n<section style=\"display: inline-block;width: 568px;vertical-align: middle;border-width: 0px;align-self: center;flex: 0 0 auto;\">\n<p powered-by=\"xiumi.us\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247484255&idx=1&sn=1b040e0e73483aef6172fd5cc6c4ef3c&chksm=c1b17ea2f6c6f7b4111a4d2b3a62889182e873f7a1b529dddbe2252ff4252b0b7b6d8438eebf&scene=21#wechat_redirect\" textvalue=\"\u672a\u6765\u65e9\u77e5\u9053\uff1a\u7528Keras\u7684\u6df1\u5ea6\u5b66\u4e60\u9884\u6d4b\u75be\u75c5\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\"><span style=\"letter-spacing: 0.034em;\">\u672a<\/span><span style=\"letter-spacing: 0.034em;\">\u6765\u65e9\u77e5\u9053\uff1a\u7528Keras\u7684\u6df1\u5ea6\u5b66\u4e60\u9884\u6d4b\u75be\u75c5<\/span><\/a><\/p>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:43.classicTable1:2\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:43.classicTable1:2.td@@0\" width=\"96.3700%\" style=\"padding-right: 5px;padding-left: 5px;border-top: 0px none rgb(62, 62, 62);border-right: 0px none rgb(62, 62, 62);border-left: 0px none rgb(62, 62, 62);border-bottom-style: dashed;border-bottom-color: rgb(202, 198, 198);background-color: rgb(247, 247, 247);\">\n<section powered-by=\"xiumi.us\" style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;\">\n<section style=\"display: inline-block;width: 568px;vertical-align: middle;border-width: 0px;align-self: center;flex: 0 0 auto;\">\n<p powered-by=\"xiumi.us\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247484423&idx=1&sn=93b2c79f08c9b6ab1fbc77eb0d354299&chksm=c1b179faf6c6f0ec305318a41971fa7064148d09c27e6e11972f676ab0a9e8cceeef4f4737e8&scene=21#wechat_redirect\" textvalue=\"\u4ecb\u7ecdR\u8bed\u8a00\u5305\u201cleaps\u201d\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\"><span style=\"letter-spacing: 0.034em;\">\u4ecb\u7ecdR\u8bed\u8a00\u5305\u201cleaps\u201d<\/span><\/a><\/p>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:43.classicTable1:3\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:43.classicTable1:3.td@@0\" width=\"96.3700%\" style=\"padding-right: 5px;padding-left: 5px;border-top: 0px none rgb(62, 62, 62);border-right: 0px none rgb(62, 62, 62);border-left: 0px none rgb(62, 62, 62);border-bottom-style: dashed;border-bottom-color: rgb(202, 198, 198);background-color: rgb(247, 247, 247);\">\n<section powered-by=\"xiumi.us\" style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;\">\n<section style=\"display: inline-block;width: 568px;vertical-align: middle;border-width: 0px;align-self: center;flex: 0 0 auto;\">\n<p powered-by=\"xiumi.us\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247484424&idx=1&sn=6306e5c1f2ff5a55ccf179be2aa5c516&chksm=c1b179f5f6c6f0e3af979f4ccee890af9dfd9cddce4d6d3f8fa8879312aa5f72e976046fa83d&scene=21#wechat_redirect\" textvalue=\"\u4e09\u5206\u949f\u7406\u6e05\u7528\u4ec0\u4e48\u56fe\u5448\u73b0\u8fde\u7eed\u53d8\u91cf\u6570\u636e\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\"><span 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powered-by=\"xiumi.us\">\u4eca\u5929\u5c0f\u56fe\u4e3a\u5c0f\u4f19\u4f34\u4eec\u5e26\u6765\u7684\u5206\u4eab\u4e3a\u5229\u7528DCA\u5206\u6790\u8bc4\u4ef7\u6a21\u578b\u7684\u4e34\u5e8a\u51c0\u83b7\u76ca\u7387\uff0c\u8be5\u5206\u6790\u5728\u6a21\u578b\u8bc4\u4ef7\u4e2d\u662f\u7f3a\u4e00\u4e0d\u53ef\u7684\u5206\u6790\uff0c\u5c0f\u56fe\u5c06\u901a\u8fc7\u8be5\u63a8\u6587\u4ecb\u7ecd\u5982\u4f55\u8fdb\u884c\u6a21\u578b\u8bc4\u4ef7\u548c\u6a21\u578b\u4e2d\u6307\u6807\u7684\u4e34\u5e8a\u51c0\u83b7\u76ca\u7387\uff0c\u8be5\u5206\u6790\u975e\u5e38\u503c\u5f97\u5c0f\u4f19\u4f34\u5b66\u4e60\uff0c\u5c0f\u56fe\u5f3a\u70c8\u63a8\u8350\uff0c\u63a5\u4e0b\u6765\u548c\u5c0f\u56fe\u4e00\u8d77\u5f00\u59cb\u4eca\u5929\u7684\u5b66\u4e60\u5427\uff01<br \/><\/p>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: 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10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p><strong>1.\u4f55\u4e3aDCA\u5206\u6790\uff1f<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3cHFo8Iq1AbTyWoMEa9rUQibFxpnh1QKibOdmGxWuusAPTklVancTyTRA\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p powered-by=\"xiumi.us\">\u5728\u5f00\u59cb\u8be5\u5206\u6790\u4e4b\u524d\uff0c\u5c0f\u56fe\u5148\u4e3a\u5c0f\u4f19\u4f34\u4eec\u7b80\u5355\u4ecb\u7ecd\u4e00\u4e0b\u4f55\u4e3aDCA\u5206\u6790\uff1fDCA\u66f2\u7ebf\uff0c\u5373\u51b3\u7b56\u66f2\u7ebf\u5206\u6790\u6cd5\uff08Decision Curve Analysis\uff09,\u662f\u7528\u6765\u5e2e\u52a9\u786e\u5b9a\u9ad8\u98ce\u9669\u60a3\u8005\u8fdb\u884c\u5e72\u9884\uff0c\u800c\u4f4e\u98ce\u9669\u60a3\u8005\u907f\u514d\u5e72\u9884\uff08\u907f\u514d\u8fc7\u5ea6\u533b\u7597\uff09\uff0c\u5373\u8bc4\u4ef7\u60a3\u8005\u83b7\u76ca\u7a0b\u5ea6\u7684\u4e00\u79cd\u8bc4\u4f30\u65b9\u6cd5\u3002\u8fd9\u5c31\u662f\u5c0f\u56fe\u5bf9DCA\u5206\u6790\u7684\u7b80\u5355\u4ecb\u7ecd\uff0c\u5c0f\u4f19\u4f34\u4eec\u662f\u4e0d\u662f\u5f88\u5bb9\u6613\u7406\u89e3\u5440\uff01\u6709\u4e0d\u7406\u89e3\u7684\u5c0f\u4f19\u4f34\uff0c\u53ef\u4ee5\u81ea\u884c\u5230\u7f51\u4e0a\u67e5\u8be2\u6df1\u5165\u5b66\u4e60\u5440\uff01\u9a6c\u4e0a\u548c\u5c0f\u56fe\u4e00\u8d77\u5f00\u542f\u4eca\u5929\u7684\u5b9e\u64cd\u3002<\/p>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3mJ85xYxsPVTFjPZt5CLmpjOFKoAJicpHa1CWfsOPTSiaXQlp500dd0ug\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p><strong>2.\u51c6\u5907\u9700\u8981\u7684R\u5305<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3cHFo8Iq1AbTyWoMEa9rUQibFxpnh1QKibOdmGxWuusAPTklVancTyTRA\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u5b89\u88c5\u9700\u8981\u7684R\u5305<\/span><\/code><code><span class=\"code-snippet_outer\">install.packages(<span class=\"code-snippet__string\">\"survival\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">#\u52a0\u8f7d\u9700\u8981\u7684R\u5305<\/span><\/code><code><span class=\"code-snippet_outer\">library(survival)<\/span><\/code><code><span class=\"code-snippet_outer\">library(ggDCA)<\/span><\/code><code><span class=\"code-snippet_outer\">library(tidyverse)<\/span><\/code><code><span class=\"code-snippet_outer\">source(<span class=\"code-snippet__string\">\"stdca.R\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3mJ85xYxsPVTFjPZt5CLmpjOFKoAJicpHa1CWfsOPTSiaXQlp500dd0ug\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p><strong>3.\u8bfb\u53d6\u8f93\u5165\u6570\u636e<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3cHFo8Iq1AbTyWoMEa9rUQibFxpnh1QKibOdmGxWuusAPTklVancTyTRA\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u884c\u540d\u4e3a\u6837\u672c\u540d\uff0c\u5176\u4ed6\u5217\u4e3a\u4e34\u5e8a\u56e0\u7d20\uff0c\u4e3b\u8981\u5305\u62ec\u751f\u5b58\u65f6\u95f4\uff0c\u751f\u5b58\u72b6\u6001\u7b49\u4fe1\u606f\u3002<\/span><\/code><code><span class=\"code-snippet_outer\">pbc<-read.table(<span class=\"code-snippet__string\">\"easy_input.txt\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.31296296296296294\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_ic9iaZlRv2VBjKD4ibicIJ961NhtRQ.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3d51Skic9LGPRCUDTjEPYXXD9aLEo5ic9iaZlRv2VBjKD4ibicIJ961NhtRQ\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u5220\u6389\u7f3a\u5931\u6570\u636e<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">pbc <- na.omit(pbc)<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">#\u5148\u628abili\u5206\u4e3a\u4e09\u7c7b\uff1a\u4f4e\u3001\u4e2d\u3001\u9ad8<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">pbc$catbili <- cut(pbc$bili,breaks=c(-Inf, <span class=\"code-snippet__number\">2<\/span>, <span class=\"code-snippet__number\">4<\/span>, Inf),<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"> labels=c(<span class=\"code-snippet__string\">\"low\"<\/span>,<span class=\"code-snippet__string\">\"medium\"<\/span>,<span class=\"code-snippet__string\">\"high\"<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"> <\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">#\u628astatus\u5206\u4e3a\u4e24\u7c7b\uff0c\u539f\u6765\u7684<span class=\"code-snippet__number\">2<\/span>\u4e3a\u53d8\u6210<span class=\"code-snippet__number\">1<\/span>\uff0c\u539f\u6765\u7684<span class=\"code-snippet__number\">1<\/span>\u548c<span class=\"code-snippet__number\">0<\/span>\u53d8\u6210<span class=\"code-snippet__number\">0<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">pbc$died <- pbc$status==<span class=\"code-snippet__number\">2<\/span><\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">pbc$status =ifelse(pbc$died==<span class=\"code-snippet__string\">\"TRUE\"<\/span>,<span class=\"code-snippet__number\">1<\/span>,<span class=\"code-snippet__number\">0<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3mJ85xYxsPVTFjPZt5CLmpjOFKoAJicpHa1CWfsOPTSiaXQlp500dd0ug\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p><strong>4.DCA\u5206\u6790\u8bc4\u4ef7\u6a21\u578b\u7684\u4e34\u5e8a\u51c0\u83b7\u76ca\u7387<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3cHFo8Iq1AbTyWoMEa9rUQibFxpnh1QKibOdmGxWuusAPTklVancTyTRA\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u591a\u56e0\u7d20\u56de\u5f52\u5206\u6790<\/span><\/code><code><span class=\"code-snippet_outer\">Srv = Surv(pbc$time, pbc$died)<\/span><\/code><code><span class=\"code-snippet_outer\">#\u6b64\u5904\u9009\u62e9<span class=\"code-snippet__number\">5<\/span>\u5e74\u7684\u65f6\u95f4\u8282\u70b9\uff0c\u8f93\u5165\u6587\u4ef6\u7684time\u5217\u7684\u5355\u4f4d\u662f\u5929\uff0c<span class=\"code-snippet__number\">5<\/span>\u5e74\u662f<span class=\"code-snippet__number\">1825<\/span>\u5929\u3002<\/span><\/code><code><span class=\"code-snippet_outer\">#\u4e0b\u9762\u6bcf\u4e24\u884c\u8ba1\u7b97<span class=\"code-snippet__number\">1<\/span>\u79cdcox\u6a21\u578b\u7684\u7cfb\u6570\uff0c\u540e\u9762\u5c06\u753b\u56fe\u5bf9\u6bd4<\/span><\/code><\/pre>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u6a21\u578b\u4e00<\/span><\/code><code><span class=\"code-snippet_outer\">coxmod1 = coxph(Srv ~ trt + age + sex + hepato + catbili + copper + stage, data=pbc)<\/span><\/code><code><span class=\"code-snippet_outer\">pbc$model1 = c(<span class=\"code-snippet__number\">1<\/span> - (summary(survfit(coxmod1,newdata=pbc), times=<span class=\"code-snippet__number\">1825<\/span>)$surv))<\/span><\/code><\/pre>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u6a21\u578b\u4e8c<\/span><\/code><code><span class=\"code-snippet_outer\">coxmod2 = coxph(Srv ~ ascites + spiders + edema + chol + albumin + alk.phos + ast + trig + platelet + protime, data=pbc)<\/span><\/code><code><span class=\"code-snippet_outer\">pbc$model2 = c(<span class=\"code-snippet__number\">1<\/span> - (summary(survfit(coxmod2,newdata=pbc), times=<span class=\"code-snippet__number\">1825<\/span>)$surv))<\/span><\/code><\/pre>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u6a21\u578b\u4e09<\/span><\/code><code><span class=\"code-snippet_outer\">coxmod3 = coxph(Srv ~ trt + age + sex + hepato + catbili + copper + stage + ascites + spiders + edema + chol + albumin + alk.phos + ast + trig + platelet + protime, data=pbc)<\/span><\/code><code><span class=\"code-snippet_outer\">pbc$model3 = c(<span class=\"code-snippet__number\">1<\/span> - (summary(survfit(coxmod3,newdata=pbc), times=<span class=\"code-snippet__number\">1825<\/span>)$surv))<\/span><\/code><\/pre>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u6a21\u578b\u56db<\/span><\/code><code><span class=\"code-snippet_outer\">coxmod4 = coxph(Srv ~ stage, data=pbc)<\/span><\/code><code><span class=\"code-snippet_outer\">pbc$model4 = c(<span class=\"code-snippet__number\">1<\/span> - (summary(survfit(coxmod4,newdata=pbc), times=<span class=\"code-snippet__number\">1825<\/span>)$surv))<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.4009259259259259\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_MSWRp2ALhYU5yAHGuLfzJ4dZsjyr9g.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3AICTaMkR0Lr8ToNjiaoL9GRiaIMSWRp2ALhYU5yAHGuLfzJ4dZsjyr9g\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u753b\u4e00\u6761\u4e34\u5e8a\u51c0\u83b7\u76ca\u7387<\/span><\/code><code><span class=\"code-snippet_outer\">mod1<-stdca(data=pbc, outcome=<span class=\"code-snippet__string\">\"status\"<\/span>, ttoutcome=<span class=\"code-snippet__string\">\"time\"<\/span>, timepoint=<span class=\"code-snippet__number\">1825<\/span>, <\/span><\/code><code><span class=\"code-snippet_outer\"> predictors=<span class=\"code-snippet__string\">\"model1\"<\/span>,cmprsk=TRUE,smooth=TRUE, xstop=<span class=\"code-snippet__number\">0.5<\/span>,intervention=<span class=\"code-snippet__string\">\"FALSE\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.9852507374631269\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_gevCTTzeGd8ugojBXCpItfNO9WKMSA.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t33xvqUCXPkNaLm7JplbtaYUWMgevCTTzeGd8ugojBXCpItfNO9WKMSA\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"678\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u591a\u4e2a\u6a21\u578b\u6bd4\u8f83<\/span><\/code><code><span class=\"code-snippet_outer\">pdf(<span class=\"code-snippet__string\">\"net_benefit.pdf\"<\/span>,width = <span class=\"code-snippet__number\">6<\/span>,height = <span class=\"code-snippet__number\">6<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">stdca(data=pbc, outcome=<span class=\"code-snippet__string\">\"status\"<\/span>, ttoutcome=<span class=\"code-snippet__string\">\"time\"<\/span>, timepoint=<span class=\"code-snippet__number\">1825<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> predictors=c(<span class=\"code-snippet__string\">\"model1\"<\/span>,<span class=\"code-snippet__string\">\"model2\"<\/span>,<span class=\"code-snippet__string\">\"model3\"<\/span>,<span class=\"code-snippet__string\">\"model4\"<\/span>), <\/span><\/code><code><span class=\"code-snippet_outer\"> cmprsk=TRUE, smooth=TRUE, <\/span><\/code><code><span class=\"code-snippet_outer\"> xstop=<span class=\"code-snippet__number\">0.5<\/span>,intervention=<span class=\"code-snippet__string\">\"FALSE\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">dev.off()<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"1.0013812154696133\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_aFty4bfnQFlT216uRal82GFzYkUXwA.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3NQDHdyqsXMk9ia7mjhlzxuG1FiaFty4bfnQFlT216uRal82GFzYkUXwA\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"724\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3mJ85xYxsPVTFjPZt5CLmpjOFKoAJicpHa1CWfsOPTSiaXQlp500dd0ug\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p><strong>5.DCA\u5206\u6790\u8bc4\u4ef7\u6a21\u578b\u7684\u5e72\u9884\u4e34\u5e8a\u51c0\u83b7\u76ca\u7387<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3cHFo8Iq1AbTyWoMEa9rUQibFxpnh1QKibOdmGxWuusAPTklVancTyTRA\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u753b\u4e00\u6761\u5e72\u9884\u4e34\u5e8a\u51c0\u83b7\u76ca\u7387<\/span><\/code><code><span class=\"code-snippet_outer\">pdf(<span class=\"code-snippet__string\">\"3red.pdf\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">mod1 <- stdca(data=pbc, outcome=<span class=\"code-snippet__string\">\"status\"<\/span>, ttoutcome=<span class=\"code-snippet__string\">\"time\"<\/span>, timepoint=<span class=\"code-snippet__number\">1825<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> predictors=<span class=\"code-snippet__string\">\"model1\"<\/span>,cmprsk=TRUE,smooth=TRUE, xstop=<span class=\"code-snippet__number\">0.5<\/span>,intervention=<span class=\"code-snippet__string\">\"TRUE\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">dev.off()<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.9940828402366864\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_Px9FEKcp5HEumiacd7ibPPLwAtfeKw.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3SwiafuNgib8m1Ud2wDr1jQfS7t2jPx9FEKcp5HEumiacd7ibPPLwAtfeKw\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"676\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u591a\u6761\u6bd4\u5bf9<\/span><\/code><code><span class=\"code-snippet_outer\">pdf(<span class=\"code-snippet__string\">\"net_reduction.pdf\"<\/span>,width = <span class=\"code-snippet__number\">6<\/span>,height = <span class=\"code-snippet__number\">6<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">stdca(data=pbc, outcome=<span class=\"code-snippet__string\">\"status\"<\/span>, ttoutcome=<span class=\"code-snippet__string\">\"time\"<\/span>, timepoint=<span class=\"code-snippet__number\">1825<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\"> predictors=c(<span class=\"code-snippet__string\">\"model1\"<\/span>,<span class=\"code-snippet__string\">\"model2\"<\/span>,<span class=\"code-snippet__string\">\"model3\"<\/span>,<span class=\"code-snippet__string\">\"model4\"<\/span>), <\/span><\/code><code><span class=\"code-snippet_outer\"> cmprsk=TRUE, smooth=TRUE, <\/span><\/code><code><span class=\"code-snippet_outer\"> xstop=<span class=\"code-snippet__number\">0.5<\/span>,intervention=<span class=\"code-snippet__string\">\"TRUE\"<\/span>) <\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"1.0069204152249136\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_mtQK7EFfmkLkiaIhXXLcoaq6fVm42w.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3ayOwrWzXUoyC3tGKHVvdmt6yBmtQK7EFfmkLkiaIhXXLcoaq6fVm42w\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"578\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3mJ85xYxsPVTFjPZt5CLmpjOFKoAJicpHa1CWfsOPTSiaXQlp500dd0ug\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p><strong>6.ggDCA\u5305\u7ed8\u5236DCA\u66f2\u7ebf<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3cHFo8Iq1AbTyWoMEa9rUQibFxpnh1QKibOdmGxWuusAPTklVancTyTRA\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u6784\u5efa\u4e24\u4e2a\u6a21\u578b<\/span><\/code><code><span class=\"code-snippet_outer\">fit1 <- coxph(Surv(time,status)~age,data = pbc)<\/span><\/code><code><span class=\"code-snippet_outer\">fit2 <- coxph(Surv(time,status)~trt + age + sex + hepato + catbili + copper + stage,data = pbc)<\/span><\/code><code><span class=\"code-snippet_outer\">#\u7ed8\u5236\u5355\u4e2a\u6a21\u578b\u7684DCA\u66f2\u7ebf<\/span><\/code><code><span class=\"code-snippet_outer\">plot1 <- dca(fit1,times = <span class=\"code-snippet__number\">365<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">ggplot(plot1)<\/span><\/code><code><span class=\"code-snippet_outer\">ggsave(<span class=\"code-snippet__string\">\"dca1.pdf\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.9985272459499264\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_339d21RvMLibiaSfI3OiaRYAtUWI6A.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t36c9cEvG5VMdDnhZtuQ3jaDpTC4ia339d21RvMLibiaSfI3OiaRYAtUWI6A\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"679\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u7ed8\u5236\u4e24\u4e2a\u6a21\u578b\u7684DCA\u66f2\u7ebf<\/span><\/code><code><span class=\"code-snippet_outer\">plot2 <- dca(fit1,fit2,times = <span class=\"code-snippet__number\">365<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">ggplot(plot2)<\/span><\/code><code><span class=\"code-snippet_outer\">ggsave(<span class=\"code-snippet__string\">\"dca2.pdf\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.9955686853766618\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_u31kRZu9yKnesyxgxHZNpARX68knQg.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsYVfHxvfibr9TVPg4je22t3wTrMTO6n5bhcRgiaicBphbg2Q7u31kRZu9yKnesyxgxHZNpARX68knQg\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"677\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: 0px;font-size: 16px;letter-spacing: 0.578px;white-space: normal;\">\n<p><br \/><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: 10px;font-size: 16px;letter-spacing: 0.578px;white-space: normal;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\">\n<section style=\"padding: 7px;display: inline-block;width: 578px;vertical-align: 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powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;font-size: 16px;letter-spacing: 0.578px;white-space: normal;min-height: 40px;\">\n<section style=\"margin-right: auto;margin-bottom: -10px;margin-left: auto;width: 578px;\">\n<table width=\"100%\">\n<tbody>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:43.classicTable1:0\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:43.classicTable1:0.td@@0\" width=\"96.3700%\" style=\"padding: 10px 0px;border-style: none;border-color: rgb(62, 62, 62);background-color: rgb(249, 174, 165);\">\n<section powered-by=\"xiumi.us\" style=\"line-height: 1;text-align: center;font-size: 17px;color: rgb(255, 255, 255);letter-spacing: 5px;\">\n<p><strong>\u5f80\u671f\u63a8\u8350<\/strong><\/p>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:43.classicTable1:1\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:43.classicTable1:1.td@@0\" width=\"96.3700%\" style=\"padding-right: 5px;padding-left: 5px;border-top: 0px none rgb(62, 62, 62);border-right: 0px none rgb(62, 62, 62);border-left: 0px none rgb(62, 62, 62);border-bottom-style: dashed;border-bottom-color: rgb(202, 198, 198);background-color: rgb(247, 247, 247);\">\n<section powered-by=\"xiumi.us\" style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;\">\n<section style=\"display: inline-block;width: 568px;vertical-align: middle;border-width: 0px;align-self: center;flex: 0 0 auto;\">\n<p powered-by=\"xiumi.us\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247484255&idx=1&sn=1b040e0e73483aef6172fd5cc6c4ef3c&chksm=c1b17ea2f6c6f7b4111a4d2b3a62889182e873f7a1b529dddbe2252ff4252b0b7b6d8438eebf&scene=21#wechat_redirect\" textvalue=\"\u672a\u6765\u65e9\u77e5\u9053\uff1a\u7528Keras\u7684\u6df1\u5ea6\u5b66\u4e60\u9884\u6d4b\u75be\u75c5\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\"><span style=\"letter-spacing: 0.034em;\">\u672a<\/span><span style=\"letter-spacing: 0.034em;\">\u6765\u65e9\u77e5\u9053\uff1a\u7528Keras\u7684\u6df1\u5ea6\u5b66\u4e60\u9884\u6d4b\u75be\u75c5<\/span><\/a><\/p>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:43.classicTable1:2\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:43.classicTable1:2.td@@0\" width=\"96.3700%\" style=\"padding-right: 5px;padding-left: 5px;border-top: 0px none rgb(62, 62, 62);border-right: 0px none rgb(62, 62, 62);border-left: 0px none rgb(62, 62, 62);border-bottom-style: dashed;border-bottom-color: rgb(202, 198, 198);background-color: rgb(247, 247, 247);\">\n<section powered-by=\"xiumi.us\" style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;\">\n<section style=\"display: inline-block;width: 568px;vertical-align: middle;border-width: 0px;align-self: center;flex: 0 0 auto;\">\n<p powered-by=\"xiumi.us\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247484423&idx=1&sn=93b2c79f08c9b6ab1fbc77eb0d354299&chksm=c1b179faf6c6f0ec305318a41971fa7064148d09c27e6e11972f676ab0a9e8cceeef4f4737e8&scene=21#wechat_redirect\" textvalue=\"\u4ecb\u7ecdR\u8bed\u8a00\u5305\u201cleaps\u201d\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\"><span style=\"letter-spacing: 0.034em;\">\u4ecb\u7ecdR\u8bed\u8a00\u5305\u201cleaps\u201d<\/span><\/a><\/p>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:43.classicTable1:3\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:43.classicTable1:3.td@@0\" width=\"96.3700%\" style=\"padding-right: 5px;padding-left: 5px;border-top: 0px none rgb(62, 62, 62);border-right: 0px none rgb(62, 62, 62);border-left: 0px none rgb(62, 62, 62);border-bottom-style: dashed;border-bottom-color: rgb(202, 198, 198);background-color: rgb(247, 247, 247);\">\n<section powered-by=\"xiumi.us\" style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;\">\n<section style=\"display: inline-block;width: 568px;vertical-align: middle;border-width: 0px;align-self: center;flex: 0 0 auto;\">\n<p powered-by=\"xiumi.us\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247484424&idx=1&sn=6306e5c1f2ff5a55ccf179be2aa5c516&chksm=c1b179f5f6c6f0e3af979f4ccee890af9dfd9cddce4d6d3f8fa8879312aa5f72e976046fa83d&scene=21#wechat_redirect\" textvalue=\"\u4e09\u5206\u949f\u7406\u6e05\u7528\u4ec0\u4e48\u56fe\u5448\u73b0\u8fde\u7eed\u53d8\u91cf\u6570\u636e\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\"><span style=\"letter-spacing: 0.034em;\">\u4e09\u5206\u949f\u7406\u6e05\u7528\u4ec0\u4e48\u56fe\u5448<\/span><span style=\"letter-spacing: 0.034em;\">\u73b0\u8fde\u7eed\u53d8\u91cf\u6570\u636e<\/span><\/a><\/p>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/section>\n<\/section>\n<p powered-by=\"xiumi.us\" style=\"margin-bottom: 0px;font-size: 16px;letter-spacing: 0.578px;white-space: normal;\"><br \/><\/p>\n<p powered-by=\"xiumi.us\" style=\"margin-bottom: 0px;font-size: 16px;letter-spacing: 0.578px;white-space: normal;\">\ud83d\udc47\u70b9\u51fb\u9605\u8bfb\u539f\u6587\u8fdb\u5165\u7f51\u5740<span style=\"letter-spacing: 0.034em;\"><\/span><\/p>\n<\/section>\n<p style=\"display: none;margin-bottom: 24px;\"><mp-style-type data-value=\"3\"><\/mp-style-type><\/p>\n<div class=\"msg_source_url\"><a href=\"http:\/\/www.biocloudservice.com\/home.html\" target=\"_blank\" rel=\"noopener\">\u9605\u8bfb\u539f\u6587<\/a><\/div>\n<p><\/content><\/p>\n<div 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[…]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/58527"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=58527"}],"version-history":[{"count":1,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/58527\/revisions"}],"predecessor-version":[{"id":58537,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/58527\/revisions\/58537"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=58527"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=58527"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=58527"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}