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0 auto;min-width: 5%;height: auto;background-color: rgb(249, 172, 172);box-shadow: rgb(249, 172, 172) 0px 0px 5px 3px;\">\n<section powered-by=\"xiumi.us\" style=\"text-align: center;transform: translate3d(2px, 0px, 0px);margin-top: -14px;margin-bottom: -14px;\">\n<p>{ \u70b9\u51fb\u84dd\u5b57\uff0c\u5173\u6ce8\u6211\u4eec }<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"text-indent: 0em;\">clusterProfiler\u662f\u4e00\u4e2a\u7528\u4e8e\u751f\u7269\u4fe1\u606f\u5b66\u548c\u529f\u80fd\u5bcc\u96c6\u5206\u6790\u7684R\u8bed\u8a00\u5305\uff0c\u5b83\u53ef\u4ee5\u5bf9\u57fa\u56e0\u96c6\u5408\u8fdb\u884c\u529f\u80fd\u6ce8\u91ca\u548c\u5bcc\u96c6\u5206\u6790\uff0c\u4ece\u800c\u5e2e\u52a9\u7814\u7a76\u4eba\u5458\u7406\u89e3\u5927\u89c4\u6a21\u57fa\u56e0\u8868\u8fbe\u6570\u636e\u7684\u751f\u7269\u5b66\u610f\u4e49\u3002<\/p>\n<p style=\"text-indent: 0em;\"><br \/><\/p>\n<p style=\"text-indent: 0em;\">clusterProfiler\u53ef\u4ee5\u7528\u4e8e\u5bf9\u591a\u4e2a\u7269\u79cd\u7684\u57fa\u56e0\u96c6\u5408\u8fdb\u884c\u529f\u80fd\u6ce8\u91ca\u548c\u5bcc\u96c6\u5206\u6790\uff0c\u5305\u62ec\u57fa\u56e0\u672c\u4f53\uff08\u751f\u7269\u8fc7\u7a0b\u3001\u7ec6\u80de\u7ec4\u5206\u3001\u5206\u5b50\u529f\u80fd\uff09\u4ee5\u53ca\u57fa\u56e0\u901a\u8def\uff08KEGG\u3001Reactome\u7b49\uff09\u3002\u8be5\u8f6f\u4ef6\u5305\u901a\u8fc7\u7edf\u8ba1\u65b9\u6cd5\u6765\u786e\u5b9a\u54ea\u4e9b\u529f\u80fd\u548c\u901a\u8def\u5728\u7ed9\u5b9a\u57fa\u56e0\u96c6\u5408\u4e2d\u8fc7\u4e8e\u5bcc\u96c6\uff0c\u4ece\u800c\u5e2e\u52a9\u7528\u6237\u4e86\u89e3\u8fd9\u4e9b\u57fa\u56e0\u7684\u529f\u80fd\u548c\u8c03\u63a7\u673a\u5236\u3002\u4eca\u5929\u5c0f\u5e08\u59b9\u4e3b\u8981\u7ed9\u5927\u5bb6\u4ecb\u7ecd\u5982\u4f55\u5229\u7528\u8fd9\u4e2aR\u5305\u6765\u8fdb\u884cGene Ontology\u7684\u5bcc\u96c6\u5206\u6790\u3002<\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;align-self: flex-start;flex: 0 0 auto;min-width: 5%;height: auto;\">\n<section powered-by=\"xiumi.us\" style=\"justify-content: flex-start;display: flex;flex-flow: row nowrap;\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgb(189, 216, 245);min-width: 5%;height: auto;padding: 6px 15px;\">\n<section powered-by=\"xiumi.us\" style=\"color: rgb(255, 255, 255);text-align: justify;\">\n<p><strong>01<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: -6px;transform: scale(0.66);transform-origin: left top;\">\n<section style=\"line-height: 1;transform: translate3d(12px, 0px, 0px);\">\n<section style=\"width: 0px;display: inline-block;border-top-width: 0.6em;border-top-style: solid;border-top-color: rgb(247, 221, 223);border-left-width: 0.6em;border-left-style: solid;border-left-color: rgb(247, 221, 223);border-bottom-width: 0.6em !important;border-bottom-style: solid !important;border-bottom-color: transparent !important;border-right-width: 0.6em !important;border-right-style: solid !important;border-right-color: transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 100 100 0%;height: auto;align-self: flex-start;background-color: rgb(255, 229, 231);padding: 6px 6px 6px 14px;\">\n<section powered-by=\"xiumi.us\" style=\"text-align: justify;\">\n<p><strong>\u5b89\u88c5\u52a0\u8f7d\u5305<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p>\u9996\u5148\u6211\u4eec\u9700\u8981\u5b89\u88c5\u5e76\u8f7d\u5165ClusterProfiler \u5305<\/p>\n<p><strong>\u4ee3\u7801\uff1a<\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"r\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">if<\/span> (!require(<span class=\"code-snippet__string\">\"BiocManager\"<\/span>, quietly = <span class=\"code-snippet__literal\">TRUE<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\">install.packages(<span class=\"code-snippet__string\">\"BiocManager\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">BiocManager::install(<span class=\"code-snippet__string\">\"clusterProfiler\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;align-self: flex-start;flex: 0 0 auto;min-width: 5%;height: auto;\">\n<section powered-by=\"xiumi.us\" style=\"justify-content: flex-start;display: flex;flex-flow: row nowrap;\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgb(189, 216, 245);min-width: 5%;height: auto;padding: 6px 15px;\">\n<section powered-by=\"xiumi.us\" style=\"color: rgb(255, 255, 255);text-align: justify;\">\n<p><strong>02<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: -6px;transform: scale(0.66);transform-origin: left top;\">\n<section style=\"line-height: 1;transform: translate3d(12px, 0px, 0px);\">\n<section style=\"width: 0px;display: inline-block;border-top-width: 0.6em;border-top-style: solid;border-top-color: rgb(247, 221, 223);border-left-width: 0.6em;border-left-style: solid;border-left-color: rgb(247, 221, 223);border-bottom-width: 0.6em !important;border-bottom-style: solid !important;border-bottom-color: transparent !important;border-right-width: 0.6em !important;border-right-style: solid !important;border-right-color: transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 100 100 0%;height: auto;align-self: flex-start;background-color: rgb(255, 229, 231);padding: 6px 6px 6px 14px;\">\n<section powered-by=\"xiumi.us\" style=\"text-align: justify;\">\n<p><strong>\u8f7d\u5165\u6570\u636e<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<p powered-by=\"xiumi.us\" style=\"text-indent: 0em;\">\u51c6\u5907\u4e00\u4e2a\u57fa\u56e0\u5217\u8868\uff0c\u8be5\u5217\u8868\u5305\u542b\u60a8\u611f\u5174\u8da3\u7684\u57fa\u56e0\u3002\u57fa\u56e0\u5217\u8868\u53ef\u4ee5\u662f\u57fa\u56e0\u7b26\u53f7\u3001Ensembl ID\u6216\u5176\u4ed6\u5e38\u89c1\u7684\u57fa\u56e0\u8bc6\u522b\u7b26\u3002\u4f8b\u5982\uff0c\u901a\u8fc7\u5dee\u5f02\u8868\u8fbe\u57fa\u56e0\u5206\u6790\u83b7\u5f97\u7684\u663e\u8457\u4e0a\u8c03\/\u6216\u4e0b\u8c03\u57fa\u56e0\uff0c\u5c06\u8fd9\u4e9b\u57fa\u56e0\u540d\u79f0\u4f5c\u4e3a\u8f93\u5165\u3002<\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.9986130374479889\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_BTYAXCJqsDibZicgiajMEM2vGicTnw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXhaiba5v8iaamelAspsMUmOIEqIianwVpLYibYZXZMPHy3ibnUtk86OBTYAXCJqsDibZicgiajMEM2vGicTnw\/640?wx_fmt=png'\" data-type=\"gif\" data-w=\"721\" style=\"width: 318px;height: 318px;\" data-recalc-dims=\"1\" \/><\/p>\n<section powered-by=\"xiumi.us\" style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.9980430528375733\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_kXak92DT4bszIuZqj1dv3753eo0dVw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXhaiba5v8iaamelAspsMUmOI7icwGKvOC7YIiaYK2M2oRhUYc0kXak92DT4bszIuZqj1dv3753eo0dVw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"511\" style=\"vertical-align: middle;width: 0px;\" data-recalc-dims=\"1\" \/><span style=\"color: rgb(160, 160, 160);font-size: 12px;\">\u56fe1 \u57fa\u56e0\u5217\u8868\u6587\u4ef6\u5185\u5bb9\u793a\u4f8b<\/span><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p><strong>\u4ee3\u7801\uff1a<\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"r\"><code><span class=\"code-snippet_outer\">genes <- read.delim(<span class=\"code-snippet__string\">'gene.txt'<\/span>, header = <span class=\"code-snippet__literal\">TRUE<\/span>, stringsAsFactors = <span class=\"code-snippet__literal\">FALSE<\/span>)[[<span class=\"code-snippet__number\">1<\/span>]]<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;align-self: flex-start;flex: 0 0 auto;min-width: 5%;height: auto;\">\n<section powered-by=\"xiumi.us\" style=\"justify-content: flex-start;display: flex;flex-flow: row nowrap;\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgb(189, 216, 245);min-width: 5%;height: auto;padding: 6px 15px;\">\n<section powered-by=\"xiumi.us\" style=\"color: rgb(255, 255, 255);text-align: justify;\">\n<p><strong>03<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: -6px;transform: scale(0.66);transform-origin: left top;\">\n<section style=\"line-height: 1;transform: translate3d(12px, 0px, 0px);\">\n<section style=\"width: 0px;display: inline-block;border-top-width: 0.6em;border-top-style: solid;border-top-color: rgb(247, 221, 223);border-left-width: 0.6em;border-left-style: solid;border-left-color: rgb(247, 221, 223);border-bottom-width: 0.6em !important;border-bottom-style: solid !important;border-bottom-color: transparent !important;border-right-width: 0.6em !important;border-right-style: solid !important;border-right-color: transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 100 100 0%;height: auto;align-self: flex-start;background-color: rgb(255, 229, 231);padding: 6px 6px 6px 14px;\">\n<section powered-by=\"xiumi.us\" style=\"text-align: justify;\">\n<p><strong>\u8fdb\u884c\u57fa\u56e0\u6ce8\u91ca<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<p powered-by=\"xiumi.us\" style=\"text-indent: 0em;\">\u4f7f\u7528bitr\u51fd\u6570\u5bf9\u57fa\u56e0\u5217\u8868\u8fdb\u884c\u57fa\u56e0\u6ce8\u91ca\u3002\u8be5\u51fd\u6570\u53ef\u4ee5\u5c06\u57fa\u56e0\u8bc6\u522b\u7b26\u6620\u5c04\u5230GO\u6ce8\u91ca\u4fe1\u606f\u3002\u8fdb\u884cGO\u5206\u6790\u65f6\uff0c\u9700\u8981\u8003\u8651\u7684\u4e00\u4e2a\u57fa\u7840\u56e0\u7d20\u5c31\u662f\u57fa\u56e0\u7684GO\u6ce8\u91ca\u4fe1\u606f\u4ece\u4f55\u5904\u83b7\u53d6\u3002Bioconductor\u4e0a\u63d0\u4f9b\u4e86\u4ee5\u4e0b19\u4e2a\u7269\u79cd\u7684Org\u7c7b\u578b\u7684\u5305\uff0c\u5305\u542b\u4e86\u8fd9\u4e9b\u7269\u79cd\u7684GO\u6ce8\u91ca\u4fe1\u606f\u3002<\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.7539267015706806\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_2HliamrVuytia9qWFEVXD9HYibSjNQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXhaiba5v8iaamelAspsMUmOI6ldVgtEOz57uH95n7xpoaPKicqsa2HliamrVuytia9qWFEVXD9HYibSjNQ\/640?wx_fmt=png'\" data-type=\"gif\" data-w=\"955\" style=\"width: 392px;height: 296px;\" data-recalc-dims=\"1\" \/><\/p>\n<section powered-by=\"xiumi.us\" style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.7537619699042407\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_rBAb7NnjIyW2UCM7ZGhRYlCpJViajg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXhaiba5v8iaamelAspsMUmOIr5wDWeiaBXe0xfic2AzNQGgk3okrBAb7NnjIyW2UCM7ZGhRYlCpJViajg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"731\" style=\"vertical-align: middle;width: 0px;\" data-recalc-dims=\"1\" \/><span style=\"color: rgb(160, 160, 160);font-size: 12px;\">\u56fe2 Bioconductor\u63d0\u4f9bGO\u6ce8\u91ca\u7684\u7269\u79cd\u4e0eR\u5305\u540d\u79f0<\/span><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p>\u5bf9\u4e8e\u4ee5\u4e0a19\u4e2a\u7269\u79cd\uff0c\u53ea\u9700\u8981\u5b89\u88c5\u5bf9\u5e94\u7684org\u5305\uff0cclusterProfile\u5c31\u4f1a\u81ea\u52a8\u4ece\u4e2d\u83b7\u53d6GO\u6ce8\u91ca\u4fe1\u606f\uff0c\u6211\u4eec\u53ea\u9700\u8981\u5dee\u5f02\u57fa\u56e0\u7684\u5217\u8868\u5c31\u53ef\u4ee5\u4e86\uff0c\u4f7f\u7528\u8d77\u6765\u975e\u5e38\u65b9\u4fbf\u3002<\/p>\n<p>\u793a\u4f8b\u4ee3\u7801\uff1a<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"r\"><code><span class=\"code-snippet_outer\">library(clusterProfiler)<\/span><\/code><code><span class=\"code-snippet_outer\">library(org.Hs.eg.db)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\"># \u5c06\u57fa\u56e0\u7b26\u53f7\u6620\u5c04\u5230GO\u6ce8\u91ca\uff08\u4ee5\u4eba\u7c7b\u4e3a\u4f8b\uff09<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">gene_list <- <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"GENE1\"<\/span>, <span class=\"code-snippet__string\">\"GENE2\"<\/span>, <span class=\"code-snippet__string\">\"GENE3\"<\/span>, ...)<\/span><\/code><code><span class=\"code-snippet_outer\">gene2go <- bitr(gene_list, fromType = <span class=\"code-snippet__string\">\"SYMBOL\"<\/span>, toType = <span class=\"code-snippet__string\">\"ENTREZID\"<\/span>, OrgDb = org.Hs.eg.db)<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;align-self: flex-start;flex: 0 0 auto;min-width: 5%;height: auto;\">\n<section powered-by=\"xiumi.us\" style=\"justify-content: flex-start;display: flex;flex-flow: row nowrap;\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgb(189, 216, 245);min-width: 5%;height: auto;padding: 6px 15px;\">\n<section powered-by=\"xiumi.us\" style=\"color: rgb(255, 255, 255);text-align: justify;\">\n<p><strong>04<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: -6px;transform: scale(0.66);transform-origin: left top;\">\n<section style=\"line-height: 1;transform: translate3d(12px, 0px, 0px);\">\n<section style=\"width: 0px;display: inline-block;border-top-width: 0.6em;border-top-style: solid;border-top-color: rgb(247, 221, 223);border-left-width: 0.6em;border-left-style: solid;border-left-color: rgb(247, 221, 223);border-bottom-width: 0.6em !important;border-bottom-style: solid !important;border-bottom-color: transparent !important;border-right-width: 0.6em !important;border-right-style: solid !important;border-right-color: transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 100 100 0%;height: auto;align-self: flex-start;background-color: rgb(255, 229, 231);padding: 6px 6px 6px 14px;\">\n<section powered-by=\"xiumi.us\" style=\"text-align: justify;\">\n<p><strong>\u8fdb\u884cGO\u5bcc\u96c6\u5206\u6790<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p>\u4f7f\u7528enrichGO\u51fd\u6570\u5bf9\u6ce8\u91ca\u540e\u7684\u57fa\u56e0\u8fdb\u884cGO\u5bcc\u96c6\u5206\u6790\u3002\u8be5\u51fd\u6570\u6839\u636e\u57fa\u56e0\u5728\u7279\u5b9aGO\u672f\u8bed\u4e2d\u7684\u5bcc\u96c6\u7a0b\u5ea6\u8ba1\u7b97\u5bcc\u96c6\u5206\u6570\u548c\u8c03\u6574\u7684p\u503c\u3002\u60a8\u53ef\u4ee5\u9009\u62e9\u4e0d\u540c\u7684\u7edf\u8ba1\u65b9\u6cd5\u548c\u53c2\u6570\u8bbe\u7f6e\u3002<\/p>\n<p><strong>\u4ee3\u7801\uff1a<\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"r\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#GO\u5bcc\u96c6\u5206\u6790<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">enrich.go <- enrichGO(gene = genes, <span class=\"code-snippet__comment\">#\u5f85\u5bcc\u96c6\u7684\u57fa\u56e0\u5217\u8868<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">OrgDb = <span class=\"code-snippet__string\">'org.Hs.eg.db'<\/span>, <span class=\"code-snippet__comment\">#\u6307\u5b9a\u7269\u79cd\u7684\u57fa\u56e0\u6570\u636e\u5e93\uff0c\u793a\u4f8b\u7269\u79cd\u662f\u4eba\u7c7b<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">keyType = <span class=\"code-snippet__string\">'ENSEMBL'<\/span>, <span class=\"code-snippet__comment\">#\u6307\u5b9a\u7ed9\u5b9a\u7684\u57fa\u56e0\u540d\u79f0\u7c7b\u578b\uff0c\u4f8b\u5982\u8fd9\u91cc\u4ee5 ensembl id \u4e3a\u4f8b<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">ont = <span class=\"code-snippet__string\">'ALL'<\/span>, <span class=\"code-snippet__comment\">#GO Ontology\uff0c\u53ef\u9009 BP\u3001MF\u3001CC\uff0c\u4e5f\u53ef\u4ee5\u6307\u5b9a ALL \u540c\u65f6\u8ba1\u7b97 3 \u8005<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">pAdjustMethod = <span class=\"code-snippet__string\">'fdr'<\/span>, <span class=\"code-snippet__comment\">#\u6307\u5b9a p \u503c\u6821\u6b63\u65b9\u6cd5<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">pvalueCutoff = <span class=\"code-snippet__number\">0.05<\/span>, <span class=\"code-snippet__comment\">#\u6307\u5b9a p \u503c\u9608\u503c\uff08\u53ef\u6307\u5b9a 1 \u4ee5\u8f93\u51fa\u5168\u90e8\uff09<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">qvalueCutoff = <span class=\"code-snippet__number\">0.2<\/span>, <span class=\"code-snippet__comment\">#\u6307\u5b9a q \u503c\u9608\u503c\uff08\u53ef\u6307\u5b9a 1 \u4ee5\u8f93\u51fa\u5168\u90e8\uff09<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">readable = <span class=\"code-snippet__literal\">FALSE<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u8f93\u51fa<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">write.table(enrich.go, <span class=\"code-snippet__string\">'enrich.go.txt'<\/span>, sep = <span class=\"code-snippet__string\">'t'<\/span>, row.names = <span class=\"code-snippet__literal\">FALSE<\/span>, <span class=\"code-snippet__built_in\">quote<\/span> = <span class=\"code-snippet__literal\">FALSE<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<p powered-by=\"xiumi.us\">\u5728\u4e0a\u8ff0\u4ee3\u7801\u4e2d\uff0c\u4f7f\u7528\u4e86\u4eba\u7c7b\u7684\u57fa\u56e0\u6ce8\u91ca\u6570\u636e\u5e93\uff08org.Hs.eg.db\uff09\uff0c\u8bbe\u7f6e\u4e86p\u503c\u548cq\u503c\u7684\u9608\u503c\u3002<\/p>\n<section powered-by=\"xiumi.us\" style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;align-self: flex-start;flex: 0 0 auto;min-width: 5%;height: auto;\">\n<section powered-by=\"xiumi.us\" style=\"justify-content: flex-start;display: flex;flex-flow: row nowrap;\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgb(189, 216, 245);min-width: 5%;height: auto;padding: 6px 15px;\">\n<section powered-by=\"xiumi.us\" style=\"color: rgb(255, 255, 255);text-align: justify;\">\n<p><strong>05<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: -6px;transform: scale(0.66);transform-origin: left top;\">\n<section style=\"line-height: 1;transform: translate3d(12px, 0px, 0px);\">\n<section style=\"width: 0px;display: inline-block;border-top-width: 0.6em;border-top-style: solid;border-top-color: rgb(247, 221, 223);border-left-width: 0.6em;border-left-style: solid;border-left-color: rgb(247, 221, 223);border-bottom-width: 0.6em !important;border-bottom-style: solid !important;border-bottom-color: transparent !important;border-right-width: 0.6em !important;border-right-style: solid !important;border-right-color: transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 100 100 0%;height: auto;align-self: flex-start;background-color: rgb(255, 229, 231);padding: 6px 6px 6px 14px;\">\n<section powered-by=\"xiumi.us\" style=\"text-align: justify;\">\n<p><strong>\u7ed3\u679c\u89e3\u91ca\u548c\u53ef\u89c6\u5316<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"text-indent: 0em;\">\u67e5\u770b\u5bcc\u96c6\u5206\u6790\u7684\u7ed3\u679c\uff0c\u4e86\u89e3\u5728\u7ed9\u5b9a\u57fa\u56e0\u5217\u8868\u4e2d\u5bcc\u96c6\u7684GO\u672f\u8bed\u3002\u53ef\u4ee5\u4f7f\u7528summary\u51fd\u6570\u548cbarplot\u3001dotplot\u7b49\u51fd\u6570\u5bf9\u7ed3\u679c\u8fdb\u884c\u6458\u8981\u548c\u53ef\u89c6\u5316\u3002<\/p>\n<p style=\"text-indent: 0em;\"><br \/><\/p>\n<p style=\"text-indent: 0em;\"><strong><span style=\"color: rgb(239, 135, 135);\">summary\u51fd\u6570\uff1asummary(enrich.go)<\/span><\/strong><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.11203703703703703\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_aJDg4DWRIFqmw0x0GricLGsc3l5TGw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXhaiba5v8iaamelAspsMUmOI1lfiac8enNQh5MX29l2gTXTh00aJDg4DWRIFqmw0x0GricLGsc3l5TGw\/640?wx_fmt=png'\" data-type=\"gif\" data-w=\"1080\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.11203703703703703\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_VsdPib9JjcibzYR7Gn1Jib5iacdtZQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXhaiba5v8iaamelAspsMUmOIVxatzoPkSS5NsegB9VBh1lRKjiaz7VsdPib9JjcibzYR7Gn1Jib5iacdtZQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 0px;\" data-recalc-dims=\"1\" \/><span style=\"color: rgb(160, 160, 160);font-size: 12px;\">\u56fe3 \u67e5\u770b\u5bcc\u96c6\u5206\u6790\u7ed3\u679c\u6458\u8981<\/span><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"color: rgb(239, 135, 135);\">\n<p 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style=\"text-align: justify;color: rgb(249, 172, 172);\">\n<p>E<\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;align-self: center;flex: 0 0 auto;min-width: 5%;height: auto;border-width: 1px;border-style: solid;border-color: rgb(249, 172, 172);padding-right: 8px;padding-left: 8px;margin-right: 10px;\">\n<section powered-by=\"xiumi.us\" style=\"text-align: justify;color: rgb(249, 172, 172);\">\n<p>N<\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;align-self: center;flex: 0 0 auto;min-width: 5%;height: auto;border-width: 1px;border-style: solid;border-color: rgb(249, 172, 172);padding-right: 8px;padding-left: 8px;margin-right: 10px;\">\n<section powered-by=\"xiumi.us\" style=\"text-align: justify;color: rgb(249, 172, 172);\">\n<p>D<\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;align-self: center;flex: 100 100 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{"id":58615,"date":"2024-06-16T23:17:43","date_gmt":"2024-06-16T15:17:43","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=58615"},"modified":"2024-06-16T23:17:43","modified_gmt":"2024-06-16T15:17:43","slug":"%e6%89%8b%e6%8a%8a%e6%89%8b%e6%95%99%e4%bd%a0%e7%94%a8deseq2-%e8%bf%9b%e8%a1%8c%e5%9f%ba%e5%9b%a0%e8%a1%a8%e8%be%be%e5%b7%ae%e5%bc%82%e5%88%86%e6%9e%90","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=58615","title":{"rendered":"\u624b\u628a\u624b\u6559\u4f60\u7528DESeq2 \u8fdb\u884c\u57fa\u56e0\u8868\u8fbe\u5dee\u5f02\u5206\u6790"},"content":{"rendered":"

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data={\"mp\":\"\u751f\u4fe1\u679c\",\"title\":\"\u624b\u628a\u624b\u6559\u4f60\u7528DESeq2 \u8fdb\u884c\u57fa\u56e0\u8868\u8fbe\u5dee\u5f02\u5206\u6790\",\"time\":\"2023-07-07 19:00:20\",\"timeStamp\":\"1688727620\"};\n<\/script><br \/>\n<body><\/p>\n<div class=\"rich_media\">\n<h1 class=\"rich_media_title\" id=\"activity-name\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247489827&idx=2&sn=9f63dfb5f61309e3fc74ef5e74d509fe&chksm=cf7c89e6f80b00f04c9ed743d3e140a9dc77737e6d193082d005d03de24892ca4002ea1c82a4#rd\" target=\"_blank\" rel=\"noopener\">\u624b\u628a\u624b\u6559\u4f60\u7528DESeq2 \u8fdb\u884c\u57fa\u56e0\u8868\u8fbe\u5dee\u5f02\u5206\u6790<\/a><\/h1>\n<div id=\"meta_content\" class=\"rich_media_meta_list\"><span class=\"rich_media_meta rich_media_meta_text\">\u5c0f\u5e08\u59b9 <\/span><span class=\"rich_media_meta rich_media_meta_nickname\" id=\"profileBt\"><a href=\"javascript:void(0);\" class=\"wx_tap_link js_wx_tap_highlight weui-wa-hotarea\" id=\"js_name\">\u751f\u4fe1\u679c <\/a><\/span><em id=\"publish_time\" class=\"rich_media_meta rich_media_meta_text\">2023-07-07 19:00:20<\/em><\/div>\n<p><content><\/p>\n<div class=\"reprint\">\n<p>\u8f6c\u81ea\u516c\u4f17\u53f7\uff1aR\u8bed\u8a00\u5b66\u5f92<br \/><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg5MDk3Mzg4OA==&mid=2247484379&idx=1&sn=f25fe1269ae680532d2da5aa6cc1b508\" target=\"_blank\" title=\"\u9605\u8bfb\u539f\u6587\" rel=\"noopener\">http:\/\/mp.weixin.qq.com\/s?__biz=Mzg5MDk3Mzg4OA==&mid=2247484379&idx=1&sn=f25fe1269ae680532d2da5aa6cc1b508<\/a><\/p>\n<\/div>\n<section style=\"font-size: 16px;letter-spacing: normal;white-space: normal;caret-color: rgb(0, 0, 0);color: rgb(0, 0, 0);margin-bottom: 24px;\">\n<section powered-by=\"xiumi.us\" style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;margin-top: 20px;margin-bottom: 25px;\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: flex-start;flex: 0 0 auto;min-width: 5%;height: auto;background-color: rgb(249, 172, 172);box-shadow: rgb(249, 172, 172) 0px 0px 5px 3px;\">\n<section powered-by=\"xiumi.us\" style=\"text-align: center;transform: translate3d(2px, 0px, 0px);margin-top: -14px;margin-bottom: -14px;\">\n<p>{ \u70b9\u51fb\u84dd\u5b57\uff0c\u5173\u6ce8\u6211\u4eec }<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"text-indent: 0em;\">clusterProfiler\u662f\u4e00\u4e2a\u7528\u4e8e\u751f\u7269\u4fe1\u606f\u5b66\u548c\u529f\u80fd\u5bcc\u96c6\u5206\u6790\u7684R\u8bed\u8a00\u5305\uff0c\u5b83\u53ef\u4ee5\u5bf9\u57fa\u56e0\u96c6\u5408\u8fdb\u884c\u529f\u80fd\u6ce8\u91ca\u548c\u5bcc\u96c6\u5206\u6790\uff0c\u4ece\u800c\u5e2e\u52a9\u7814\u7a76\u4eba\u5458\u7406\u89e3\u5927\u89c4\u6a21\u57fa\u56e0\u8868\u8fbe\u6570\u636e\u7684\u751f\u7269\u5b66\u610f\u4e49\u3002<\/p>\n<p style=\"text-indent: 0em;\"><br \/><\/p>\n<p style=\"text-indent: 0em;\">clusterProfiler\u53ef\u4ee5\u7528\u4e8e\u5bf9\u591a\u4e2a\u7269\u79cd\u7684\u57fa\u56e0\u96c6\u5408\u8fdb\u884c\u529f\u80fd\u6ce8\u91ca\u548c\u5bcc\u96c6\u5206\u6790\uff0c\u5305\u62ec\u57fa\u56e0\u672c\u4f53\uff08\u751f\u7269\u8fc7\u7a0b\u3001\u7ec6\u80de\u7ec4\u5206\u3001\u5206\u5b50\u529f\u80fd\uff09\u4ee5\u53ca\u57fa\u56e0\u901a\u8def\uff08KEGG\u3001Reactome\u7b49\uff09\u3002\u8be5\u8f6f\u4ef6\u5305\u901a\u8fc7\u7edf\u8ba1\u65b9\u6cd5\u6765\u786e\u5b9a\u54ea\u4e9b\u529f\u80fd\u548c\u901a\u8def\u5728\u7ed9\u5b9a\u57fa\u56e0\u96c6\u5408\u4e2d\u8fc7\u4e8e\u5bcc\u96c6\uff0c\u4ece\u800c\u5e2e\u52a9\u7528\u6237\u4e86\u89e3\u8fd9\u4e9b\u57fa\u56e0\u7684\u529f\u80fd\u548c\u8c03\u63a7\u673a\u5236\u3002\u4eca\u5929\u5c0f\u5e08\u59b9\u4e3b\u8981\u7ed9\u5927\u5bb6\u4ecb\u7ecd\u5982\u4f55\u5229\u7528\u8fd9\u4e2aR\u5305\u6765\u8fdb\u884cGene Ontology\u7684\u5bcc\u96c6\u5206\u6790\u3002<\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;align-self: flex-start;flex: 0 0 auto;min-width: 5%;height: auto;\">\n<section powered-by=\"xiumi.us\" style=\"justify-content: flex-start;display: flex;flex-flow: row nowrap;\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgb(189, 216, 245);min-width: 5%;height: auto;padding: 6px 15px;\">\n<section powered-by=\"xiumi.us\" style=\"color: rgb(255, 255, 255);text-align: justify;\">\n<p><strong>01<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: -6px;transform: scale(0.66);transform-origin: left top;\">\n<section style=\"line-height: 1;transform: translate3d(12px, 0px, 0px);\">\n<section style=\"width: 0px;display: inline-block;border-top-width: 0.6em;border-top-style: solid;border-top-color: rgb(247, 221, 223);border-left-width: 0.6em;border-left-style: solid;border-left-color: rgb(247, 221, 223);border-bottom-width: 0.6em !important;border-bottom-style: solid !important;border-bottom-color: transparent !important;border-right-width: 0.6em !important;border-right-style: solid !important;border-right-color: transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 100 100 0%;height: auto;align-self: flex-start;background-color: rgb(255, 229, 231);padding: 6px 6px 6px 14px;\">\n<section powered-by=\"xiumi.us\" style=\"text-align: justify;\">\n<p><strong>\u5b89\u88c5\u52a0\u8f7d\u5305<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p>\u9996\u5148\u6211\u4eec\u9700\u8981\u5b89\u88c5\u5e76\u8f7d\u5165ClusterProfiler \u5305<\/p>\n<p><strong>\u4ee3\u7801\uff1a<\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"r\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">if<\/span> (!require(<span class=\"code-snippet__string\">\"BiocManager\"<\/span>, quietly = <span class=\"code-snippet__literal\">TRUE<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\">install.packages(<span class=\"code-snippet__string\">\"BiocManager\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">BiocManager::install(<span class=\"code-snippet__string\">\"clusterProfiler\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;align-self: flex-start;flex: 0 0 auto;min-width: 5%;height: auto;\">\n<section powered-by=\"xiumi.us\" style=\"justify-content: flex-start;display: flex;flex-flow: row nowrap;\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgb(189, 216, 245);min-width: 5%;height: auto;padding: 6px 15px;\">\n<section powered-by=\"xiumi.us\" style=\"color: rgb(255, 255, 255);text-align: justify;\">\n<p><strong>02<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: -6px;transform: scale(0.66);transform-origin: left top;\">\n<section style=\"line-height: 1;transform: translate3d(12px, 0px, 0px);\">\n<section style=\"width: 0px;display: inline-block;border-top-width: 0.6em;border-top-style: solid;border-top-color: rgb(247, 221, 223);border-left-width: 0.6em;border-left-style: solid;border-left-color: rgb(247, 221, 223);border-bottom-width: 0.6em !important;border-bottom-style: solid !important;border-bottom-color: transparent !important;border-right-width: 0.6em !important;border-right-style: solid !important;border-right-color: transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 100 100 0%;height: auto;align-self: flex-start;background-color: rgb(255, 229, 231);padding: 6px 6px 6px 14px;\">\n<section powered-by=\"xiumi.us\" style=\"text-align: justify;\">\n<p><strong>\u8f7d\u5165\u6570\u636e<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<p powered-by=\"xiumi.us\" style=\"text-indent: 0em;\">\u51c6\u5907\u4e00\u4e2a\u57fa\u56e0\u5217\u8868\uff0c\u8be5\u5217\u8868\u5305\u542b\u60a8\u611f\u5174\u8da3\u7684\u57fa\u56e0\u3002\u57fa\u56e0\u5217\u8868\u53ef\u4ee5\u662f\u57fa\u56e0\u7b26\u53f7\u3001Ensembl ID\u6216\u5176\u4ed6\u5e38\u89c1\u7684\u57fa\u56e0\u8bc6\u522b\u7b26\u3002\u4f8b\u5982\uff0c\u901a\u8fc7\u5dee\u5f02\u8868\u8fbe\u57fa\u56e0\u5206\u6790\u83b7\u5f97\u7684\u663e\u8457\u4e0a\u8c03\/\u6216\u4e0b\u8c03\u57fa\u56e0\uff0c\u5c06\u8fd9\u4e9b\u57fa\u56e0\u540d\u79f0\u4f5c\u4e3a\u8f93\u5165\u3002<\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.9986130374479889\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_BTYAXCJqsDibZicgiajMEM2vGicTnw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXhaiba5v8iaamelAspsMUmOIEqIianwVpLYibYZXZMPHy3ibnUtk86OBTYAXCJqsDibZicgiajMEM2vGicTnw\/640?wx_fmt=png'\" data-type=\"gif\" data-w=\"721\" style=\"width: 318px;height: 318px;\" data-recalc-dims=\"1\" \/><\/p>\n<section powered-by=\"xiumi.us\" style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.9980430528375733\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_kXak92DT4bszIuZqj1dv3753eo0dVw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXhaiba5v8iaamelAspsMUmOI7icwGKvOC7YIiaYK2M2oRhUYc0kXak92DT4bszIuZqj1dv3753eo0dVw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"511\" style=\"vertical-align: middle;width: 0px;\" data-recalc-dims=\"1\" \/><span style=\"color: rgb(160, 160, 160);font-size: 12px;\">\u56fe1 \u57fa\u56e0\u5217\u8868\u6587\u4ef6\u5185\u5bb9\u793a\u4f8b<\/span><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p><strong>\u4ee3\u7801\uff1a<\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"r\"><code><span class=\"code-snippet_outer\">genes <- read.delim(<span class=\"code-snippet__string\">'gene.txt'<\/span>, header = <span class=\"code-snippet__literal\">TRUE<\/span>, stringsAsFactors = <span class=\"code-snippet__literal\">FALSE<\/span>)[[<span class=\"code-snippet__number\">1<\/span>]]<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;align-self: flex-start;flex: 0 0 auto;min-width: 5%;height: auto;\">\n<section powered-by=\"xiumi.us\" style=\"justify-content: flex-start;display: flex;flex-flow: row nowrap;\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgb(189, 216, 245);min-width: 5%;height: auto;padding: 6px 15px;\">\n<section powered-by=\"xiumi.us\" style=\"color: rgb(255, 255, 255);text-align: justify;\">\n<p><strong>03<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: -6px;transform: scale(0.66);transform-origin: left top;\">\n<section style=\"line-height: 1;transform: translate3d(12px, 0px, 0px);\">\n<section style=\"width: 0px;display: inline-block;border-top-width: 0.6em;border-top-style: solid;border-top-color: rgb(247, 221, 223);border-left-width: 0.6em;border-left-style: solid;border-left-color: rgb(247, 221, 223);border-bottom-width: 0.6em !important;border-bottom-style: solid !important;border-bottom-color: transparent !important;border-right-width: 0.6em !important;border-right-style: solid !important;border-right-color: transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 100 100 0%;height: auto;align-self: flex-start;background-color: rgb(255, 229, 231);padding: 6px 6px 6px 14px;\">\n<section powered-by=\"xiumi.us\" style=\"text-align: justify;\">\n<p><strong>\u8fdb\u884c\u57fa\u56e0\u6ce8\u91ca<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<p powered-by=\"xiumi.us\" style=\"text-indent: 0em;\">\u4f7f\u7528bitr\u51fd\u6570\u5bf9\u57fa\u56e0\u5217\u8868\u8fdb\u884c\u57fa\u56e0\u6ce8\u91ca\u3002\u8be5\u51fd\u6570\u53ef\u4ee5\u5c06\u57fa\u56e0\u8bc6\u522b\u7b26\u6620\u5c04\u5230GO\u6ce8\u91ca\u4fe1\u606f\u3002\u8fdb\u884cGO\u5206\u6790\u65f6\uff0c\u9700\u8981\u8003\u8651\u7684\u4e00\u4e2a\u57fa\u7840\u56e0\u7d20\u5c31\u662f\u57fa\u56e0\u7684GO\u6ce8\u91ca\u4fe1\u606f\u4ece\u4f55\u5904\u83b7\u53d6\u3002Bioconductor\u4e0a\u63d0\u4f9b\u4e86\u4ee5\u4e0b19\u4e2a\u7269\u79cd\u7684Org\u7c7b\u578b\u7684\u5305\uff0c\u5305\u542b\u4e86\u8fd9\u4e9b\u7269\u79cd\u7684GO\u6ce8\u91ca\u4fe1\u606f\u3002<\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.7539267015706806\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_2HliamrVuytia9qWFEVXD9HYibSjNQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXhaiba5v8iaamelAspsMUmOI6ldVgtEOz57uH95n7xpoaPKicqsa2HliamrVuytia9qWFEVXD9HYibSjNQ\/640?wx_fmt=png'\" data-type=\"gif\" data-w=\"955\" style=\"width: 392px;height: 296px;\" data-recalc-dims=\"1\" \/><\/p>\n<section powered-by=\"xiumi.us\" style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.7537619699042407\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_rBAb7NnjIyW2UCM7ZGhRYlCpJViajg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXhaiba5v8iaamelAspsMUmOIr5wDWeiaBXe0xfic2AzNQGgk3okrBAb7NnjIyW2UCM7ZGhRYlCpJViajg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"731\" style=\"vertical-align: middle;width: 0px;\" data-recalc-dims=\"1\" \/><span style=\"color: rgb(160, 160, 160);font-size: 12px;\">\u56fe2 Bioconductor\u63d0\u4f9bGO\u6ce8\u91ca\u7684\u7269\u79cd\u4e0eR\u5305\u540d\u79f0<\/span><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p>\u5bf9\u4e8e\u4ee5\u4e0a19\u4e2a\u7269\u79cd\uff0c\u53ea\u9700\u8981\u5b89\u88c5\u5bf9\u5e94\u7684org\u5305\uff0cclusterProfile\u5c31\u4f1a\u81ea\u52a8\u4ece\u4e2d\u83b7\u53d6GO\u6ce8\u91ca\u4fe1\u606f\uff0c\u6211\u4eec\u53ea\u9700\u8981\u5dee\u5f02\u57fa\u56e0\u7684\u5217\u8868\u5c31\u53ef\u4ee5\u4e86\uff0c\u4f7f\u7528\u8d77\u6765\u975e\u5e38\u65b9\u4fbf\u3002<\/p>\n<p>\u793a\u4f8b\u4ee3\u7801\uff1a<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"r\"><code><span class=\"code-snippet_outer\">library(clusterProfiler)<\/span><\/code><code><span class=\"code-snippet_outer\">library(org.Hs.eg.db)<\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\"># \u5c06\u57fa\u56e0\u7b26\u53f7\u6620\u5c04\u5230GO\u6ce8\u91ca\uff08\u4ee5\u4eba\u7c7b\u4e3a\u4f8b\uff09<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">gene_list <- <span class=\"code-snippet__built_in\">c<\/span>(<span class=\"code-snippet__string\">\"GENE1\"<\/span>, <span class=\"code-snippet__string\">\"GENE2\"<\/span>, <span class=\"code-snippet__string\">\"GENE3\"<\/span>, ...)<\/span><\/code><code><span class=\"code-snippet_outer\">gene2go <- bitr(gene_list, fromType = <span class=\"code-snippet__string\">\"SYMBOL\"<\/span>, toType = <span class=\"code-snippet__string\">\"ENTREZID\"<\/span>, OrgDb = org.Hs.eg.db)<\/span><\/code><\/pre>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;align-self: flex-start;flex: 0 0 auto;min-width: 5%;height: auto;\">\n<section powered-by=\"xiumi.us\" style=\"justify-content: flex-start;display: flex;flex-flow: row nowrap;\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgb(189, 216, 245);min-width: 5%;height: auto;padding: 6px 15px;\">\n<section powered-by=\"xiumi.us\" style=\"color: rgb(255, 255, 255);text-align: justify;\">\n<p><strong>04<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: -6px;transform: scale(0.66);transform-origin: left top;\">\n<section style=\"line-height: 1;transform: translate3d(12px, 0px, 0px);\">\n<section style=\"width: 0px;display: inline-block;border-top-width: 0.6em;border-top-style: solid;border-top-color: rgb(247, 221, 223);border-left-width: 0.6em;border-left-style: solid;border-left-color: rgb(247, 221, 223);border-bottom-width: 0.6em !important;border-bottom-style: solid !important;border-bottom-color: transparent !important;border-right-width: 0.6em !important;border-right-style: solid !important;border-right-color: transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 100 100 0%;height: auto;align-self: flex-start;background-color: rgb(255, 229, 231);padding: 6px 6px 6px 14px;\">\n<section powered-by=\"xiumi.us\" style=\"text-align: justify;\">\n<p><strong>\u8fdb\u884cGO\u5bcc\u96c6\u5206\u6790<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p>\u4f7f\u7528enrichGO\u51fd\u6570\u5bf9\u6ce8\u91ca\u540e\u7684\u57fa\u56e0\u8fdb\u884cGO\u5bcc\u96c6\u5206\u6790\u3002\u8be5\u51fd\u6570\u6839\u636e\u57fa\u56e0\u5728\u7279\u5b9aGO\u672f\u8bed\u4e2d\u7684\u5bcc\u96c6\u7a0b\u5ea6\u8ba1\u7b97\u5bcc\u96c6\u5206\u6570\u548c\u8c03\u6574\u7684p\u503c\u3002\u60a8\u53ef\u4ee5\u9009\u62e9\u4e0d\u540c\u7684\u7edf\u8ba1\u65b9\u6cd5\u548c\u53c2\u6570\u8bbe\u7f6e\u3002<\/p>\n<p><strong>\u4ee3\u7801\uff1a<\/strong><\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"r\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#GO\u5bcc\u96c6\u5206\u6790<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">enrich.go <- enrichGO(gene = genes, <span class=\"code-snippet__comment\">#\u5f85\u5bcc\u96c6\u7684\u57fa\u56e0\u5217\u8868<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">OrgDb = <span class=\"code-snippet__string\">'org.Hs.eg.db'<\/span>, <span class=\"code-snippet__comment\">#\u6307\u5b9a\u7269\u79cd\u7684\u57fa\u56e0\u6570\u636e\u5e93\uff0c\u793a\u4f8b\u7269\u79cd\u662f\u4eba\u7c7b<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">keyType = <span class=\"code-snippet__string\">'ENSEMBL'<\/span>, <span class=\"code-snippet__comment\">#\u6307\u5b9a\u7ed9\u5b9a\u7684\u57fa\u56e0\u540d\u79f0\u7c7b\u578b\uff0c\u4f8b\u5982\u8fd9\u91cc\u4ee5 ensembl id \u4e3a\u4f8b<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">ont = <span class=\"code-snippet__string\">'ALL'<\/span>, <span class=\"code-snippet__comment\">#GO Ontology\uff0c\u53ef\u9009 BP\u3001MF\u3001CC\uff0c\u4e5f\u53ef\u4ee5\u6307\u5b9a ALL \u540c\u65f6\u8ba1\u7b97 3 \u8005<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">pAdjustMethod = <span class=\"code-snippet__string\">'fdr'<\/span>, <span class=\"code-snippet__comment\">#\u6307\u5b9a p \u503c\u6821\u6b63\u65b9\u6cd5<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">pvalueCutoff = <span class=\"code-snippet__number\">0.05<\/span>, <span class=\"code-snippet__comment\">#\u6307\u5b9a p \u503c\u9608\u503c\uff08\u53ef\u6307\u5b9a 1 \u4ee5\u8f93\u51fa\u5168\u90e8\uff09<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">qvalueCutoff = <span class=\"code-snippet__number\">0.2<\/span>, <span class=\"code-snippet__comment\">#\u6307\u5b9a q \u503c\u9608\u503c\uff08\u53ef\u6307\u5b9a 1 \u4ee5\u8f93\u51fa\u5168\u90e8\uff09<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">readable = <span class=\"code-snippet__literal\">FALSE<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__comment\">#\u8f93\u51fa<\/span><\/span><\/code><code><span class=\"code-snippet_outer\">write.table(enrich.go, <span class=\"code-snippet__string\">'enrich.go.txt'<\/span>, sep = <span class=\"code-snippet__string\">'t'<\/span>, row.names = <span class=\"code-snippet__literal\">FALSE<\/span>, <span class=\"code-snippet__built_in\">quote<\/span> = <span class=\"code-snippet__literal\">FALSE<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<p powered-by=\"xiumi.us\">\u5728\u4e0a\u8ff0\u4ee3\u7801\u4e2d\uff0c\u4f7f\u7528\u4e86\u4eba\u7c7b\u7684\u57fa\u56e0\u6ce8\u91ca\u6570\u636e\u5e93\uff08org.Hs.eg.db\uff09\uff0c\u8bbe\u7f6e\u4e86p\u503c\u548cq\u503c\u7684\u9608\u503c\u3002<\/p>\n<section powered-by=\"xiumi.us\" style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;margin-top: 10px;margin-bottom: 10px;\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;align-self: flex-start;flex: 0 0 auto;min-width: 5%;height: auto;\">\n<section powered-by=\"xiumi.us\" style=\"justify-content: flex-start;display: flex;flex-flow: row nowrap;\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgb(189, 216, 245);min-width: 5%;height: auto;padding: 6px 15px;\">\n<section powered-by=\"xiumi.us\" style=\"color: rgb(255, 255, 255);text-align: justify;\">\n<p><strong>05<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: -6px;transform: scale(0.66);transform-origin: left top;\">\n<section style=\"line-height: 1;transform: translate3d(12px, 0px, 0px);\">\n<section style=\"width: 0px;display: inline-block;border-top-width: 0.6em;border-top-style: solid;border-top-color: rgb(247, 221, 223);border-left-width: 0.6em;border-left-style: solid;border-left-color: rgb(247, 221, 223);border-bottom-width: 0.6em !important;border-bottom-style: solid !important;border-bottom-color: transparent !important;border-right-width: 0.6em !important;border-right-style: solid !important;border-right-color: transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 100 100 0%;height: auto;align-self: flex-start;background-color: rgb(255, 229, 231);padding: 6px 6px 6px 14px;\">\n<section powered-by=\"xiumi.us\" style=\"text-align: justify;\">\n<p><strong>\u7ed3\u679c\u89e3\u91ca\u548c\u53ef\u89c6\u5316<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"text-indent: 0em;\">\u67e5\u770b\u5bcc\u96c6\u5206\u6790\u7684\u7ed3\u679c\uff0c\u4e86\u89e3\u5728\u7ed9\u5b9a\u57fa\u56e0\u5217\u8868\u4e2d\u5bcc\u96c6\u7684GO\u672f\u8bed\u3002\u53ef\u4ee5\u4f7f\u7528summary\u51fd\u6570\u548cbarplot\u3001dotplot\u7b49\u51fd\u6570\u5bf9\u7ed3\u679c\u8fdb\u884c\u6458\u8981\u548c\u53ef\u89c6\u5316\u3002<\/p>\n<p style=\"text-indent: 0em;\"><br \/><\/p>\n<p style=\"text-indent: 0em;\"><strong><span style=\"color: rgb(239, 135, 135);\">summary\u51fd\u6570\uff1asummary(enrich.go)<\/span><\/strong><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.11203703703703703\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_aJDg4DWRIFqmw0x0GricLGsc3l5TGw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXhaiba5v8iaamelAspsMUmOI1lfiac8enNQh5MX29l2gTXTh00aJDg4DWRIFqmw0x0GricLGsc3l5TGw\/640?wx_fmt=png'\" data-type=\"gif\" data-w=\"1080\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.11203703703703703\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_VsdPib9JjcibzYR7Gn1Jib5iacdtZQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXhaiba5v8iaamelAspsMUmOIVxatzoPkSS5NsegB9VBh1lRKjiaz7VsdPib9JjcibzYR7Gn1Jib5iacdtZQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 0px;\" data-recalc-dims=\"1\" \/><span style=\"color: rgb(160, 160, 160);font-size: 12px;\">\u56fe3 \u67e5\u770b\u5bcc\u96c6\u5206\u6790\u7ed3\u679c\u6458\u8981<\/span><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"color: rgb(239, 135, 135);\">\n<p style=\"text-indent: 0em;\"><strong>barplot\u51fd\u6570\uff1abarplot(enrich.go)<\/strong><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.741503604531411\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_vRES408oxAkhzWklFlbYcFicH5tDCQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXhaiba5v8iaamelAspsMUmOIw1VyABHoBrmc45hyQmOiatZicCwvRES408oxAkhzWklFlbYcFicH5tDCQ\/640?wx_fmt=png'\" data-type=\"gif\" data-w=\"971\" style=\"width: 450px;height: 334px;\" data-recalc-dims=\"1\" \/><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.7411526794742164\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_JqgbhdW7pVTdGL7KIWIwpvQ52A7xng.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXhaiba5v8iaamelAspsMUmOIiaKibV8wrsZUbnhWNcdDiadRtlQJqgbhdW7pVTdGL7KIWIwpvQ52A7xng\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"989\" style=\"vertical-align: middle;width: 0px;\" data-recalc-dims=\"1\" \/><span style=\"color: rgb(160, 160, 160);font-size: 12px;\">\u56fe4 \u5bcc\u96c6\u67f1\u5f62\u56fe<\/span><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"color: rgb(239, 135, 135);\">\n<p style=\"text-indent: 0em;\"><strong>dotplot\u51fd\u6570\uff1adotplot(enrich.go)<\/strong><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.7476635514018691\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_JWs8wdta9sjbkUed640Jk6ibPXzaoQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/oCSOtP61aEXhaiba5v8iaamelAspsMUmOIicGlwJeRUB3WoIakEqutBdHFEaJWs8wdta9sjbkUed640Jk6ibPXzaoQ\/640?wx_fmt=png'\" data-type=\"gif\" data-w=\"963\" style=\"width: 451px;height: 337px;\" data-recalc-dims=\"1\" \/><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><span style=\"color: rgb(160, 160, 160);font-size: 12px;\">\u56fe5 \u5bcc\u96c6\u6c14\u6ce1\u56fe<\/span><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"text-indent: 2em;\"><br \/><\/p>\n<p style=\"text-indent: 0em;\">\u4ee5\u4e0a\u6b65\u9aa4\u662f\u5c0f\u5e08\u59b9\u63d0\u4f9b\u7684\u4f7f\u7528clusterProfiler\u8fdb\u884c\u57fa\u56e0\u672c\u4f53\uff08GO\uff09\u5206\u6790\u7684\u4e00\u822c\u6d41\u7a0b\uff0c\u60a8\u53ef\u4ee5\u6839\u636e\u60a8\u7684\u5177\u4f53\u9700\u6c42\u548c\u6570\u636e\u8fdb\u884c\u76f8\u5e94\u7684\u8c03\u6574\u548c\u6269\u5c55\u3002\u603b\u4e4b\uff0cclusterProfiler\u662f\u4e00\u4e2a\u5f3a\u5927\u7684R\u8bed\u8a00\u5305\uff0c\u53ef\u7528\u4e8e\u751f\u7269\u4fe1\u606f\u5b66\u548c\u529f\u80fd\u5bcc\u96c6\u5206\u6790\uff0c\u63d0\u4f9b\u4e86\u4e30\u5bcc\u7684\u529f\u80fd\u6ce8\u91ca\u548c\u5bcc\u96c6\u5206\u6790\u5de5\u5177\uff0c\u6709\u52a9\u4e8e\u7814\u7a76\u4eba\u5458\u5bf9\u57fa\u56e0\u96c6\u5408\u7684\u751f\u7269\u5b66\u610f\u4e49\u8fdb\u884c\u6df1\u5165\u5206\u6790\u3002\u66f4\u591a\u5b66\u4e60\u8d44\u6e90\u8bf7\u5927\u5bb6\u79fb\u6b65\u5c0f\u5e08\u59b9\u4e13\u5c5e\u4e91\u751f\u4fe1\u5e73\u53f0\uff08\u4e91\u751f\u4fe1 – \u5b66\u751f\u7269\u4fe1\u606f\u5b66 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