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100%;\">\n<section style=\"display: flex;justify-content: center;flex-direction: row;\">\n<section style=\"display: inline-block;width: 100%;flex: 0 0 auto;align-self: flex-start;vertical-align: top;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;border-style: solid;border-width: 1px;border-color: rgb(67, 67, 67);height: auto;box-shadow: rgb(255, 219, 118) 6px 6px 0px;background-color: rgb(255, 255, 255);width: 100%;\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row nowrap;\">\n<section style=\"display: inline-block;vertical-align: top;width: 70.0348%;align-self: flex-start;flex: 0 0 auto;height: auto;max-width: 70.0348% !important;\">\n<section style=\"margin-top: 10px;\" powered-by=\"xiumi.us\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"text-align: center;\">\n<p style=\"text-indent: 0em;line-height: 1.75em;\"><span style=\"letter-spacing: 0.5px;\"><strong><span style=\"font-size: 15px;\">\u751f\u4fe1\u4ebaR\u8bed\u8a00\u5b66\u4e60\u5fc5\u5907<\/span><\/strong><\/span><\/p>\n<p style=\"text-indent: 0em;line-height: 1.75em;\"><span style=\"letter-spacing: 0.5px;\"><strong><span style=\"font-size: 15px;\">\u7acb\u523b\u62e5\u6709\u4e00\u4e2aRstudio\u8d26\u53f7<\/span><\/strong><\/span><\/p>\n<p style=\"text-indent: 0em;line-height: 1.75em;\"><span style=\"letter-spacing: 0.5px;\"><strong><span style=\"font-size: 15px;\">\u5f00\u542f\u5347\u7ea7\u6a21\u5f0f\u5427<\/span><\/strong><\/span><\/p>\n<p style=\"text-indent: 0em;line-height: 1.75em;\"><span style=\"color: rgb(255, 129, 36);font-size: 12px;letter-spacing: 0.5px;\">\uff0856\u7ebf\u7a0b\uff0c256G\u5185\u5b58\uff0c\u4e2a\u4eba\u5b58\u50a81T\uff09<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: 29.9652%;align-self: flex-start;flex: 0 0 auto;height: auto;max-width: 29.9652% !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;\" powered-by=\"xiumi.us\">\n<section style=\"text-align: center;line-height: 0;\">\n<section>\n<section style=\"display: inline-block;vertical-align: middle;\" powered-by=\"xiumi.us\">\n<section style=\"line-height: 0;\">\n<section style=\"width: 111px;\" powered-by=\"xiumi.us\">\n<section style=\"line-height: 1.75em;text-indent: 0em;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;height: auto;width: 111px;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"1\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_GBhsibRAgNiaQsH4ichdP9ibEhHMFA-106.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyL6u7wJswOp8vtpzGp6vYngnlT6jiavu08Bvp2iblzGf3IkoBD9NGBhsibRAgNiaQsH4ichdP9ibEhHMFA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"400\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<section style=\"display: contents;\" powered-by=\"xiumi.us\">\n<section style=\"display: contents;\">\n<section style=\"display: contents;\">\n<section style=\"height: 0px;overflow: hidden;\"><span style=\"font-size: 14px;letter-spacing: 0.578px;caret-color: red;\"> <\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p><br \/><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><span style=\"font-size: 14px;\">\u6709\u7684\u5c0f\u4f19\u4f34\u53ef\u80fd\u542c\u8bf4\u8fc7\u66fc\u54c8\u987f\u56fe\uff0c\u4f46\u662f\u5e76\u4e0d\u4e86\u89e3\uff0c\u4e5f\u4e0d\u77e5\u9053\u662f\u6765\u505a\u4ec0\u4e48\u7684\uff0c\u5176\u5b9e\uff0c\u66fc\u54c8\u987f\u56e0\u4e3a\u5176\u5f62\u4f3c\u66fc\u54c8\u987f\u6469\u5929\u5927\u697c\uff0c\u6240\u4ee5\u88ab\u79f0\u4e3a\u66fc\u54c8\u987f\u56fe\u3002\u672c\u8d28\u4e0a\u5c31\u662f\u6563\u70b9\u56fe\uff0c\u6211\u4eec\u4e00\u822c\u7528\u6765\u5c55\u793a\u5927\u91cf\u975e\u96f6\u7684\u6ce2\u52a8\u6570\u636e\u3002Y\u8f74\u9ad8\u70b9\u662f\u7528\u6765\u663e\u793a\u5177\u6709\u76f8\u5173\u6027\u7684\u4f4d\u70b9\u3002\u5e73\u65f6\u6211\u4eec\u7528\u7684\u6700\u591a\u7684\u5c31\u662f\u5168\u57fa\u56e0\u7ec4\u5173\u8054\u5206\u6790\u7814\u7a76\u4e2d\u4e5f\u5c31\u662fG<\/span>WAS\uff0c\u56e0\u4e3a\u66fc\u54c8\u987f\u56fe\u53ef\u4ee5\u4e00\u76ee\u4e86\u7136\u7684\u67e5\u770b\u57fa\u56e0\u7684\u9891\u7387\u548c\u5206\u5e03\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u5c0f\u4f19\u4f34\u662f\u4e0d\u662f\u4e86\u89e3\u4e86\u5f88\u591a\uff0c\u4e0b\u9762\u5c0f\u679c\u5c31\u5e26\u5927\u5bb6\u53bb\u5b66\u4e60\u4e00\u4e0b\u5982\u4f55\u7ed8\u5236\u66fc\u54c8\u987f\u56fe\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u66fc\u54c8\u987f\u56fe\u7ed8\u5236\u65b9\u6cd5\u6709\u5f88\u591a\u79cd\uff0c\u4eca\u5929\u5c31\u5e26\u5927\u5bb6\u4e86\u89e3\u4e00\u4e0b\uff1a<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">install.packages(‘qqman’)<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">library(qqman)#<span style=\"font-size: 14px;\">\u8fd9\u91cc\u4e3b\u8981\u7528\u5230qq<\/span>man<span style=\"font-size: 14px;\">\u8fd9\u4e2aR\u5305\uff0c\u8fd9\u4e2a\u5f88\u597d\u4e0b\u8f7d\uff0c\u666e\u901a\u65b9\u5f0f\u5c31\u53ef\u4ee5\u4e0b\u8f7d\u3002<\/span><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><span style=\"font-size: 14px;\">\u8fd9\u91cc\u6211\u4eec\u4f7f\u7528R\u5305qqman\u81ea\u5e26\u7684\u5b9e\u4f8b\u6570\u636e\u96c6qwas<\/span> \u53bb\u4e3a\u5927\u5bb6\u5c55\u793a\uff0c<\/span><span style=\"mso-spacerun:'yes';font-family:\u7b49\u7ebf;mso-bidi-font-family:'Times New Roman';font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><br \/><\/span><\/p>\n<\/section>\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.4012345679012346\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_iaweRalu66NJhWcVFMVQnJhTgRnbCw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqz45ybV5XgvUSoPz8dH4m0FRS1iaweRalu66NJhWcVFMVQnJhTgRnbCw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"324\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u5c0f\u4f19\u4f34\u53ef\u4ee5\u6309\u7167\u8fd9\u4e2a\u5f62\u5f0f\u53bb\u8bbe\u7f6e\u81ea\u5df1\u7684\u6570\u636e<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u5176\u4e2dSNP\u662fsnp\u540d\u79f0\uff0cCHR\u662f\u67d3\u8272\u4f53\u7684\u7f16\u53f7\uff0cBP\u662f\u78b1\u57fa\u7684\u4f4d\u7f6e\uff0cP\u5c31\u662fP\u503c\u5566<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u6211\u4eec\u5148\u7ed8\u5236\u7b80\u5355\u7684\u66fc\u54c8\u987f\u56femanhattan\uff1a<\/span><span style=\"mso-spacerun:'yes';font-family:\u7b49\u7ebf;mso-bidi-font-family:'Times New Roman';font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p style=\"text-align: center;white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"objectivec\"><code><span class=\"code-snippet_outer\">manhattan(gwasResults, col = c(<span class=\"code-snippet__string\">\"blue4\"<\/span>, <span class=\"code-snippet__string\">\"orange3\"<\/span>), main = <span class=\"code-snippet__string\">\"Results from simulated trait\"<\/span>,genomewideline = <span class=\"code-snippet__literal\">FALSE<\/span>, suggestiveline = <span class=\"code-snippet__literal\">FALSE<\/span>,highlight = snpsOfInterest[<span class=\"code-snippet__number\">1<\/span>:<span class=\"code-snippet__number\">10<\/span>])<\/span><\/code><\/pre>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.8961038961038961\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_FsqfIkqmho7sl6W81e3LpJP4vhgPuQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqXYvribJOC5msI4xOPfzXh5RjHFsqfIkqmho7sl6W81e3LpJP4vhgPuQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 10.5pt;\">\u4f46\u662f\u8fd9\u4e2a\u56fe\u770b\u8d77\u6765\u5e73\u5e73\u65e0\u5947\uff0c\u6211\u4eec\u52a0\u70b9\u7ec6\u8282\uff0c\u52a0\u5165\u6807\u9898\uff0c\u8c03\u6574\u989c\u8272\uff0c\u628a\u90e8\u5206SNP\u9ad8\u4eae\u7b49\u4e00\u4e9b\u7ec6\u8282\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 10.5pt;\">head(snpOfInterest) #\u8fd9\u91cc\u6211\u4eec\u5148\u67e5\u770b\u5185\u7f6e\u9ad8\u4eaesnp\u6570\u636e\uff0c snpOfInterest\u53ef\u81ea\u884c\u8bbe\u7f6e<\/span><span style=\"mso-spacerun:'yes';font-family:\u7b49\u7ebf;mso-bidi-font-family:'Times New Roman';font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><br \/><\/p>\n<p style=\"text-align: center;white-space: normal;font-size: 16px;\"><o:p><\/o:p><\/p>\n<\/section>\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"objectivec\"><code><span class=\"code-snippet_outer\">manhattan(gwasResults, col = c(<span class=\"code-snippet__string\">\"blue4\"<\/span>, <span class=\"code-snippet__string\">\"orange3\"<\/span>), main = <span class=\"code-snippet__string\">\"Results from simulated trait\"<\/span>,genomewideline = <span class=\"code-snippet__literal\">FALSE<\/span>, suggestiveline = <span class=\"code-snippet__literal\">FALSE<\/span>,highlight = snpsOfInterest[<span class=\"code-snippet__number\">1<\/span>:<span class=\"code-snippet__number\">10<\/span>])<\/span><\/code><\/pre>\n<\/section>\n<\/section>\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"1.0101010101010102\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_EaI4PtEJaxMeF6dbObDHAmTvr0AjsA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqsnnx1zyBdsOqvY3OeIGR40kZEaI4PtEJaxMeF6dbObDHAmTvr0AjsA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u91cc\u9762\u53c2\u6570 CHR3\u7684\u7eff\u70b9\u662f\u6765\u81easnpsOflnterest,highlight\u53c2\u6570\u63a7\u5236\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u84dd\u8272\u6a2a\u7ebf\u662f\u7531\u53c2\u6570suggestiveline\u63a7\u5236\uff0c\u7ea2\u8272\u4f7f\u7528genomewideline\u63a7\u5236<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u5c0f\u4f19\u4f34\u53ef\u4ee5\u81ea\u4fe1\u8bbe\u7f6e\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u6211\u4eec\u8fd8\u53ef\u4ee5\u628a\u57fa\u56e0\u540d\u52a0\u4e0a\u53bb\uff0c\u8fd9\u91cc\u6211\u4eec\u53bb\u6559\u5927\u5bb6\u5982\u4f55\u6279\u91cf\u8868\u793a\u57fa\u56e0\u540d\uff1a<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">gwasResults[3057,1] <- “AA” #\u8fd9\u91cc\u5c06\u5c06\u6700\u663e\u8457\u7684\u70b9\uff0c\u81ea\u5b9a\u4e49\uff0c\u53ef\u770b\u51fa\u6539\u53d8<\/span><span style=\"mso-spacerun:'yes';font-family:\u7b49\u7ebf;mso-bidi-font-family:'Times New Roman';font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><br \/><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p><br \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"objectivec\"><code><span class=\"code-snippet_outer\">manhattan(gwasResults,suggestiveline =FALSE,genomewideline =FALSE,col=c(\"#FF6A6A\",\"#43CD80\",\"#EE7600\"),annotatePval=0.05,annotateTop=TRUE)<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p style=\"text-align: center;\"><strong style=\"font-size: 16px;letter-spacing: 0.578px;text-align: center;text-wrap: wrap;\"><\/strong><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.9033189033189033\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_icc8OtUGZxg4k38miccWkpGD5HksXQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqXzv550ib1tMv9yXE7bm2C28AMMricc8OtUGZxg4k38miccWkpGD5HksXQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u8fd9\u6837\u5c31\u7ed8\u5236\u5b8c\u6210\u5566\uff0c\u4e0a\u8ff0\u4ee3\u7801\u4e2d\uff0cannotatePval\u53ef\u4ee5\u8bbe\u7f6ep\u9608\u503c\uff0c\u4f4e\u4e8e\u8be5\u503c\u7684\u6563\u70b9\u5c06\u4f1a\u5728\u56fe\u4e2d\u88ab\u6807\u8bb0\uff0cannotateTop\u9ed8\u8ba4\u4e3aTrue\uff0c\u5373\u4ec5\u6807\u8bb0p\u503c\u6700\u5c0f\u7684\u70b9\uff0c\u6240\u4ee5\u8be5\u56fe\u4e2d\u5404\u6761\u67d3\u8272\u4f53\u53ea\u6709\u4e00\u4e2asnp\u88ab\u6807\u8bb0\uff0c\u5018\u82e5annotateTop\u8bbe\u7f6e\u4e3aFalse\uff0c\u5219\u6240\u6709\u4f4e\u4e8eannotatePval\u7684\u70b9\u5747\u4f1a\u88ab\u6807\u8bb0\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u4e0a\u8ff0\u662f\u4f7f\u7528qqman\u5305\u7ed8\u5236\u66fc\u54c8\u987f\u56fe\uff0c\u5c0f\u679c\u8fd9\u91cc\u8fd8\u6709\u4e00\u79cd\u65b9\u6cd5\uff0cCMplot\u5305\u7ed8\u5236\u66fc\u54c8\u987f\u56fe\uff0c<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u8fd9\u4e2a\u5305\u53c2\u6570\u4f1a\u66f4\u591a\uff0c\u800c\u4e14\u56fe\u4f1a\u66f4\u597d\u770b\u3002\u5e76\u4e14\u53ef\u4ee5\u7ed8\u5236\u591a\u8868\u578b\u7684\u66fc\u54c8\u987f\u56fe\uff0c\u4ee5\u53cacircos\u72b6\u5c55\u793a\u3002\u662f\u4e0d\u662f\u5f88\u5fc3\u52a8\u5462\uff1f<\/span><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"objectivec\"><code><span class=\"code-snippet_outer\">library(CMplot)<\/span><\/code><code><span class=\"code-snippet_outer\">#\u6211\u4eec\u9996\u5148\u8f7d\u5165\u8fd9\u4e2a\u5305<\/span><\/code><code><span class=\"code-snippet_outer\">CMplot(pig60K,plot.type=\"m\",LOG10=TRUE,threshold=NULL,chr.den.col=NULL,file=\"jpg\",dpi=300)<\/span><\/code><code><span class=\"code-snippet_outer\">\u8fd9\u91cc\u4f7f\u7528\u5185\u90e8\u7684\u6570\u636e\u96c6pig60K\uff0c\u5c0f\u4f19\u4f34\u6839\u636e\u6570\u636e\u96c6\u5f62\u5f0f\u81ea\u884c\u53bb\u8bbe\u7f6e\uff1a<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.7682333873581848\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_50OvnN4HUdKwoenLNwjjlChWicibHg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqtrZFI1GPN0Metz5Ha7tce5g31A50OvnN4HUdKwoenLNwjjlChWicibHg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"617\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: \u7b49\u7ebf;font-size: 14px;\">\u8fd9\u4e2a\u56fe\u7ed8\u5236\u5b8c\u4f1a\u4f1a\u51fa\u73b0\u5728\u8bbe\u7f6e\u597d\u7684\u6587\u4ef6\u5939\u91cc\uff0c\u6765\u770b\u770b\u6548\u679c\uff1a<\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.42712842712842713\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_SiansX7JiaOdVaIeymnic0FYQjBVgw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqjWTs9p59ygEicqQxDwf9hvOVdwnibSiansX7JiaOdVaIeymnic0FYQjBVgw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u6211\u4eec\u7ed8\u5236SNP\u7684\u5bc6\u5ea6\u56fe\uff1a<\/span><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"swift\"><code><span class=\"code-snippet_outer\">CMplot(pig60K, plot.type=\"m\", LOG10=TRUE, ylim=NULL, threshold=c(1e-6,1e-4),threshold.lty=c(1,2), threshold.lwd=c(1,1), threshold.col=c(\"black\",\"grey\"),<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"> amplify=TRUE,chr.den.col=c(\"darkgreen\",\"yellow\",\"red\"),bin.size=1e6,signal.col=c(\"red\",\"green\"),signal.cex=c(1,1),signal.pch=c(19,19),file=\"jpg\",dpi=300)<\/span><\/code><\/pre>\n<\/section>\n<p><span style=\"mso-spacerun:'yes';font-family:\u7b49\u7ebf;mso-bidi-font-family:'Times New Roman';font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><br \/><\/o:p><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.4227994227994228\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_0ZtkllicJ0lnjoblj3TiaM2ZUeTB1g.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqGFa34XpU4TkzPUSl5ibo6v29Ccj0ZtkllicJ0lnjoblj3TiaM2ZUeTB1g\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: \u7b49\u7ebf;font-size: 14px;\">\u63a5\u4e0b\u6765\u6211\u4eec\u8fd8\u53ef\u4ee5\u5bf9\u591a\u8868\u578b\u7684\u6570\u636e\u5c55\u793a\uff1a<\/span><span style=\"mso-spacerun:'yes';font-family:\u7b49\u7ebf;mso-bidi-font-family:'Times New Roman';font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"swift\"><code><span class=\"code-snippet_outer\">CMplot(pig60K, plot.type=\"m\", multracks=TRUE, threshold=c(1e-6,1e<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"> 4),threshold.lty=c(1,2),threshold.lwd=c(1,1), threshold.col=c(\"black\",\"grey\"), amplify=TRUE,bin.size=1e6,chr.den.col=c(\"darkgreen\", \"yellow\", \"red\"), signal.col=c(\"red\",\"green\"),signal.cex=c(1,1),file=\"jpg\",memo=\"\",dpi=300)<\/span><\/code><\/pre>\n<\/section>\n<p><br \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.417027417027417\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_2Cp1TY2vHdjdekaPBGWErUCxdpDPvg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqpofjGcUGhJaVlDjISrDDjZtK2Cp1TY2vHdjdekaPBGWErUCxdpDPvg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u6211\u4eec\u8fd8\u53ef\u4ee5\u7ed8\u5236\u5708\u56fe\u4e5f\u5c31\u662fcircos\u5c55\u793a<\/span><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"objectivec\"><code><span class=\"code-snippet_outer\">CMplot(pig60K,plot.type=\"c\",chr.labels=paste(\"Chr\",c(1:18,\"X\"),sep=\"\"),r=0.4,cir.legend=TRUE,outward=FALSE,cir.legend.col=\"black\",cir.chr.h=1.3,chr.den.col=\"black\",file=\"jpg\",dpi=300)<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.9927849927849928\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/10_Xcmj3V6BUwfESiaWatO9cTlIxSsKRg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqoexWmEVicNgRJx6N6PS7czy219Xcmj3V6BUwfESiaWatO9cTlIxSsKRg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u4e0a\u8ff0\u90fd\u662f\u4f7f\u7528\u81ea\u5e26\u7684\u793a\u4f8b\u6570\u636epig60K\uff0c\u5c0f\u679c\u8fd8\u662f\u559c\u6b22circos\u7684\u56fe\u7247\uff0c\u56fe\u7247\u597d\u770b\u7cbe\u7f8e\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u4e0a\u8ff0\u5c31\u662f\u6211\u4eec\u5bf9\u66fc\u54c8\u987f\u7684\u5b66\u4e60\uff0c\u5c0f\u4f19\u4f34\u6709\u6ca1\u6709\u5b66\u4f1a\u5462\uff0c\u53bb\u51c6\u5907\u4e00\u4e0b\u81ea\u5df1\u7684\u793a\u4f8b\u6570\u636e\uff0c\u7ed8\u5236\u597d\u770b\u7684\u66fc\u54c8\u987f\u56fe\u3002\u5c0f\u679c\u8981\u63d0\u9192\u5927\u5bb6\uff0c\u8981\u591a\u591a\u7406\u89e3\u4ee3\u7801\u53c2\u6570\u7684\u610f\u4e49\uff0c\u4e0a\u8ff0\u5c0f\u679c\u5df2\u7ecf\u6807\u6ce8\u4e86\u5f88\u591a\uff0c\u5c0f\u4f19\u4f34\u4eec\u53ef\u4ee5\u6839\u636e\u81ea\u5df1\u6570\u636e\u5185\u5bb9\u5957\u7528\u8fdb\u53bb\uff0c\u4f46\u662f\u4e5f\u4e0d\u8981\u5fd8\u8bb0\u662f\u4ec0\u4e48\u542b\u4e49\uff0c\u8fd9\u6837\u624d\u80fd\u7ed8\u5236\u51fa\u81ea\u5df1\u60f3\u8981\u7684\u66fc\u54c8\u987f\u56fe\uff01<\/span><span style=\"mso-spacerun:'yes';font-family:\u7b49\u7ebf;mso-bidi-font-family:'Times New Roman';font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"mso-spacerun:'yes';font-family:\u7b49\u7ebf;mso-bidi-font-family:'Times New Roman';font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><br \/><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u4e0b\u671f\u5c06\u4e3a\u4f60\u5e26\u6765\u66f4\u591aR\u8bed\u8a00\u7684\u9a9a\u64cd\u4f5c\u6280\u5de7\uff0c\u4ee5\u4e0b\u63a8\u8350\u7684\u662f\u4e00\u4e2a\u591a\u529f\u80fd\u7684\u751f\u4fe1\u5e73\u53f0\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"color: rgb(255, 0, 0);background: rgb(255, 255, 255);font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u4e91\u751f\u4fe1\u5e73\u53f0\u94fe\u63a5\uff1a<\/span><span style=\"color: rgb(255, 0, 0);background: rgb(255, 255, 255);text-decoration: underline;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 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onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAyqVJd7As6iaIgTzXqErqUGp8QxUSk0Sricia0JSmh8nB9T4SicUwKXVVrT2bVTc2jSlZNaUIE5TUCDMQ\/640?wx_fmt=jpeg&wxfrom=5&wx_lazy=1&wx_co=1'\" data-type=\"jpeg\" data-w=\"871\" style=\"outline: 0px;border-width: 0px;border-style: initial;border-color: initial;vertical-align: middle;visibility: visible !important;width: 625px !important;\" data-recalc-dims=\"1\"><\/span><\/a><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;outline: 0px;text-align: center;line-height: 0;\">\n<section style=\"outline: 0px;vertical-align: middle;display: inline-block;line-height: 0;\"><a target=\"_blank\" href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwNjE0MDY3MQ==&mid=2650761303&idx=2&sn=6f73471d1e82c56c0b2160d0fcd32d53&scene=21#wechat_redirect\" textvalue=\"\u4f60\u5df2\u9009\u4e2d\u4e86\u6dfb\u52a0\u94fe\u63a5\u7684\u5185\u5bb9\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" tab=\"innerlink\" 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data-recalc-dims=\"1\"><\/span><\/a><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-bottom: 0px;outline: 0px;font-family: system-ui, -apple-system, BlinkMacSystemFont, "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);\"><span style=\"outline: 0px;font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 10.5pt;\"><\/span><\/p>\n<section style=\"margin-bottom: 0px;letter-spacing: 0.578px;white-space: normal;caret-color: rgba(0, 0, 0, 0);font-size: 16px;\">\n<section>\n<section style=\"margin-top: 0.5em;\">\n<section style=\"padding: 0.5em;border-width: 1px;border-style: solid;box-shadow: rgb(226, 226, 226) 0px 16px 1px -13px;border-color: rgb(0, 150, 136);\">\n<section style=\"text-align: left;\">\n<section style=\"color: rgb(255, 129, 36);text-align: justify;\">\n<section style=\"margin-bottom: 8px;\">\n<p style=\"text-indent: 0em;line-height: 1.75em;\"><span style=\"letter-spacing: 0.5px;\">\u70b9\u51fb<strong><span style=\"color: rgb(0, 150, 136);\">\u201c\u9605\u8bfb\u539f\u6587\u201d<\/span><\/strong>\u7acb\u523b\u62e5\u6709<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin-bottom: 8px;font-size: 32px;color: rgb(0, 150, 136);\">\n<p style=\"text-indent: 0em;line-height: 1.75em;\"><span style=\"letter-spacing: 0.5px;\">\u2193\u2193\u2193 <\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"display: none;\"><mp-style-type data-value=\"3\"><\/mp-style-type><\/p>\n<div class=\"msg_source_url\"><a 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data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<section style=\"display: contents;\" powered-by=\"xiumi.us\">\n<section style=\"display: contents;\">\n<section style=\"display: contents;\">\n<section style=\"height: 0px;overflow: hidden;\"><span style=\"font-size: 14px;letter-spacing: 0.578px;caret-color: red;\"> <\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p><br \/><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><span style=\"font-size: 14px;\">\u6709\u7684\u5c0f\u4f19\u4f34\u53ef\u80fd\u542c\u8bf4\u8fc7\u66fc\u54c8\u987f\u56fe\uff0c\u4f46\u662f\u5e76\u4e0d\u4e86\u89e3\uff0c\u4e5f\u4e0d\u77e5\u9053\u662f\u6765\u505a\u4ec0\u4e48\u7684\uff0c\u5176\u5b9e\uff0c\u66fc\u54c8\u987f\u56e0\u4e3a\u5176\u5f62\u4f3c\u66fc\u54c8\u987f\u6469\u5929\u5927\u697c\uff0c\u6240\u4ee5\u88ab\u79f0\u4e3a\u66fc\u54c8\u987f\u56fe\u3002\u672c\u8d28\u4e0a\u5c31\u662f\u6563\u70b9\u56fe\uff0c\u6211\u4eec\u4e00\u822c\u7528\u6765\u5c55\u793a\u5927\u91cf\u975e\u96f6\u7684\u6ce2\u52a8\u6570\u636e\u3002Y\u8f74\u9ad8\u70b9\u662f\u7528\u6765\u663e\u793a\u5177\u6709\u76f8\u5173\u6027\u7684\u4f4d\u70b9\u3002\u5e73\u65f6\u6211\u4eec\u7528\u7684\u6700\u591a\u7684\u5c31\u662f\u5168\u57fa\u56e0\u7ec4\u5173\u8054\u5206\u6790\u7814\u7a76\u4e2d\u4e5f\u5c31\u662fG<\/span>WAS\uff0c\u56e0\u4e3a\u66fc\u54c8\u987f\u56fe\u53ef\u4ee5\u4e00\u76ee\u4e86\u7136\u7684\u67e5\u770b\u57fa\u56e0\u7684\u9891\u7387\u548c\u5206\u5e03\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u5c0f\u4f19\u4f34\u662f\u4e0d\u662f\u4e86\u89e3\u4e86\u5f88\u591a\uff0c\u4e0b\u9762\u5c0f\u679c\u5c31\u5e26\u5927\u5bb6\u53bb\u5b66\u4e60\u4e00\u4e0b\u5982\u4f55\u7ed8\u5236\u66fc\u54c8\u987f\u56fe\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u66fc\u54c8\u987f\u56fe\u7ed8\u5236\u65b9\u6cd5\u6709\u5f88\u591a\u79cd\uff0c\u4eca\u5929\u5c31\u5e26\u5927\u5bb6\u4e86\u89e3\u4e00\u4e0b\uff1a<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">install.packages(‘qqman’)<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">library(qqman)#<span style=\"font-size: 14px;\">\u8fd9\u91cc\u4e3b\u8981\u7528\u5230qq<\/span>man<span style=\"font-size: 14px;\">\u8fd9\u4e2aR\u5305\uff0c\u8fd9\u4e2a\u5f88\u597d\u4e0b\u8f7d\uff0c\u666e\u901a\u65b9\u5f0f\u5c31\u53ef\u4ee5\u4e0b\u8f7d\u3002<\/span><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><span style=\"font-size: 14px;\">\u8fd9\u91cc\u6211\u4eec\u4f7f\u7528R\u5305qqman\u81ea\u5e26\u7684\u5b9e\u4f8b\u6570\u636e\u96c6qwas<\/span> \u53bb\u4e3a\u5927\u5bb6\u5c55\u793a\uff0c<\/span><span style=\"mso-spacerun:'yes';font-family:\u7b49\u7ebf;mso-bidi-font-family:'Times New Roman';font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\"><br \/><\/span><\/p>\n<\/section>\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.4012345679012346\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_iaweRalu66NJhWcVFMVQnJhTgRnbCw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqz45ybV5XgvUSoPz8dH4m0FRS1iaweRalu66NJhWcVFMVQnJhTgRnbCw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"324\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u5c0f\u4f19\u4f34\u53ef\u4ee5\u6309\u7167\u8fd9\u4e2a\u5f62\u5f0f\u53bb\u8bbe\u7f6e\u81ea\u5df1\u7684\u6570\u636e<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u5176\u4e2dSNP\u662fsnp\u540d\u79f0\uff0cCHR\u662f\u67d3\u8272\u4f53\u7684\u7f16\u53f7\uff0cBP\u662f\u78b1\u57fa\u7684\u4f4d\u7f6e\uff0cP\u5c31\u662fP\u503c\u5566<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u6211\u4eec\u5148\u7ed8\u5236\u7b80\u5355\u7684\u66fc\u54c8\u987f\u56femanhattan\uff1a<\/span><span style=\"mso-spacerun:'yes';font-family:\u7b49\u7ebf;mso-bidi-font-family:'Times New Roman';font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p style=\"text-align: center;white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"objectivec\"><code><span class=\"code-snippet_outer\">manhattan(gwasResults, col = c(<span class=\"code-snippet__string\">\"blue4\"<\/span>, <span class=\"code-snippet__string\">\"orange3\"<\/span>), main = <span class=\"code-snippet__string\">\"Results from simulated trait\"<\/span>,genomewideline = <span class=\"code-snippet__literal\">FALSE<\/span>, suggestiveline = <span class=\"code-snippet__literal\">FALSE<\/span>,highlight = snpsOfInterest[<span class=\"code-snippet__number\">1<\/span>:<span class=\"code-snippet__number\">10<\/span>])<\/span><\/code><\/pre>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.8961038961038961\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_FsqfIkqmho7sl6W81e3LpJP4vhgPuQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqXYvribJOC5msI4xOPfzXh5RjHFsqfIkqmho7sl6W81e3LpJP4vhgPuQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 10.5pt;\">\u4f46\u662f\u8fd9\u4e2a\u56fe\u770b\u8d77\u6765\u5e73\u5e73\u65e0\u5947\uff0c\u6211\u4eec\u52a0\u70b9\u7ec6\u8282\uff0c\u52a0\u5165\u6807\u9898\uff0c\u8c03\u6574\u989c\u8272\uff0c\u628a\u90e8\u5206SNP\u9ad8\u4eae\u7b49\u4e00\u4e9b\u7ec6\u8282\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 10.5pt;\">head(snpOfInterest) #\u8fd9\u91cc\u6211\u4eec\u5148\u67e5\u770b\u5185\u7f6e\u9ad8\u4eaesnp\u6570\u636e\uff0c snpOfInterest\u53ef\u81ea\u884c\u8bbe\u7f6e<\/span><span style=\"mso-spacerun:'yes';font-family:\u7b49\u7ebf;mso-bidi-font-family:'Times New Roman';font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><br \/><\/p>\n<p style=\"text-align: center;white-space: normal;font-size: 16px;\"><o:p><\/o:p><\/p>\n<\/section>\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"objectivec\"><code><span class=\"code-snippet_outer\">manhattan(gwasResults, col = c(<span class=\"code-snippet__string\">\"blue4\"<\/span>, <span class=\"code-snippet__string\">\"orange3\"<\/span>), main = <span class=\"code-snippet__string\">\"Results from simulated trait\"<\/span>,genomewideline = <span class=\"code-snippet__literal\">FALSE<\/span>, suggestiveline = <span class=\"code-snippet__literal\">FALSE<\/span>,highlight = snpsOfInterest[<span class=\"code-snippet__number\">1<\/span>:<span class=\"code-snippet__number\">10<\/span>])<\/span><\/code><\/pre>\n<\/section>\n<\/section>\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"1.0101010101010102\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_EaI4PtEJaxMeF6dbObDHAmTvr0AjsA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqsnnx1zyBdsOqvY3OeIGR40kZEaI4PtEJaxMeF6dbObDHAmTvr0AjsA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u91cc\u9762\u53c2\u6570 CHR3\u7684\u7eff\u70b9\u662f\u6765\u81easnpsOflnterest,highlight\u53c2\u6570\u63a7\u5236\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u84dd\u8272\u6a2a\u7ebf\u662f\u7531\u53c2\u6570suggestiveline\u63a7\u5236\uff0c\u7ea2\u8272\u4f7f\u7528genomewideline\u63a7\u5236<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u5c0f\u4f19\u4f34\u53ef\u4ee5\u81ea\u4fe1\u8bbe\u7f6e\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u6211\u4eec\u8fd8\u53ef\u4ee5\u628a\u57fa\u56e0\u540d\u52a0\u4e0a\u53bb\uff0c\u8fd9\u91cc\u6211\u4eec\u53bb\u6559\u5927\u5bb6\u5982\u4f55\u6279\u91cf\u8868\u793a\u57fa\u56e0\u540d\uff1a<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">gwasResults[3057,1] <- “AA” #\u8fd9\u91cc\u5c06\u5c06\u6700\u663e\u8457\u7684\u70b9\uff0c\u81ea\u5b9a\u4e49\uff0c\u53ef\u770b\u51fa\u6539\u53d8<\/span><span style=\"mso-spacerun:'yes';font-family:\u7b49\u7ebf;mso-bidi-font-family:'Times New Roman';font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><br \/><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\">\n<p><br \/><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"objectivec\"><code><span class=\"code-snippet_outer\">manhattan(gwasResults,suggestiveline =FALSE,genomewideline =FALSE,col=c(\"#FF6A6A\",\"#43CD80\",\"#EE7600\"),annotatePval=0.05,annotateTop=TRUE)<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p style=\"text-align: center;\"><strong style=\"font-size: 16px;letter-spacing: 0.578px;text-align: center;text-wrap: wrap;\"><\/strong><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.9033189033189033\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_icc8OtUGZxg4k38miccWkpGD5HksXQ.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqXzv550ib1tMv9yXE7bm2C28AMMricc8OtUGZxg4k38miccWkpGD5HksXQ\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u8fd9\u6837\u5c31\u7ed8\u5236\u5b8c\u6210\u5566\uff0c\u4e0a\u8ff0\u4ee3\u7801\u4e2d\uff0cannotatePval\u53ef\u4ee5\u8bbe\u7f6ep\u9608\u503c\uff0c\u4f4e\u4e8e\u8be5\u503c\u7684\u6563\u70b9\u5c06\u4f1a\u5728\u56fe\u4e2d\u88ab\u6807\u8bb0\uff0cannotateTop\u9ed8\u8ba4\u4e3aTrue\uff0c\u5373\u4ec5\u6807\u8bb0p\u503c\u6700\u5c0f\u7684\u70b9\uff0c\u6240\u4ee5\u8be5\u56fe\u4e2d\u5404\u6761\u67d3\u8272\u4f53\u53ea\u6709\u4e00\u4e2asnp\u88ab\u6807\u8bb0\uff0c\u5018\u82e5annotateTop\u8bbe\u7f6e\u4e3aFalse\uff0c\u5219\u6240\u6709\u4f4e\u4e8eannotatePval\u7684\u70b9\u5747\u4f1a\u88ab\u6807\u8bb0\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u4e0a\u8ff0\u662f\u4f7f\u7528qqman\u5305\u7ed8\u5236\u66fc\u54c8\u987f\u56fe\uff0c\u5c0f\u679c\u8fd9\u91cc\u8fd8\u6709\u4e00\u79cd\u65b9\u6cd5\uff0cCMplot\u5305\u7ed8\u5236\u66fc\u54c8\u987f\u56fe\uff0c<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-size: 14px;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;\">\u8fd9\u4e2a\u5305\u53c2\u6570\u4f1a\u66f4\u591a\uff0c\u800c\u4e14\u56fe\u4f1a\u66f4\u597d\u770b\u3002\u5e76\u4e14\u53ef\u4ee5\u7ed8\u5236\u591a\u8868\u578b\u7684\u66fc\u54c8\u987f\u56fe\uff0c\u4ee5\u53cacircos\u72b6\u5c55\u793a\u3002\u662f\u4e0d\u662f\u5f88\u5fc3\u52a8\u5462\uff1f<\/span><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"objectivec\"><code><span class=\"code-snippet_outer\">library(CMplot)<\/span><\/code><code><span class=\"code-snippet_outer\">#\u6211\u4eec\u9996\u5148\u8f7d\u5165\u8fd9\u4e2a\u5305<\/span><\/code><code><span class=\"code-snippet_outer\">CMplot(pig60K,plot.type=\"m\",LOG10=TRUE,threshold=NULL,chr.den.col=NULL,file=\"jpg\",dpi=300)<\/span><\/code><code><span class=\"code-snippet_outer\">\u8fd9\u91cc\u4f7f\u7528\u5185\u90e8\u7684\u6570\u636e\u96c6pig60K\uff0c\u5c0f\u4f19\u4f34\u6839\u636e\u6570\u636e\u96c6\u5f62\u5f0f\u81ea\u884c\u53bb\u8bbe\u7f6e\uff1a<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><br \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.7682333873581848\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_50OvnN4HUdKwoenLNwjjlChWicibHg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqtrZFI1GPN0Metz5Ha7tce5g31A50OvnN4HUdKwoenLNwjjlChWicibHg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"617\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: \u7b49\u7ebf;font-size: 14px;\">\u8fd9\u4e2a\u56fe\u7ed8\u5236\u5b8c\u4f1a\u4f1a\u51fa\u73b0\u5728\u8bbe\u7f6e\u597d\u7684\u6587\u4ef6\u5939\u91cc\uff0c\u6765\u770b\u770b\u6548\u679c\uff1a<\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.42712842712842713\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_SiansX7JiaOdVaIeymnic0FYQjBVgw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqjWTs9p59ygEicqQxDwf9hvOVdwnibSiansX7JiaOdVaIeymnic0FYQjBVgw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u6211\u4eec\u7ed8\u5236SNP\u7684\u5bc6\u5ea6\u56fe\uff1a<\/span><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"swift\"><code><span class=\"code-snippet_outer\">CMplot(pig60K, plot.type=\"m\", LOG10=TRUE, ylim=NULL, threshold=c(1e-6,1e-4),threshold.lty=c(1,2), threshold.lwd=c(1,1), threshold.col=c(\"black\",\"grey\"),<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"> amplify=TRUE,chr.den.col=c(\"darkgreen\",\"yellow\",\"red\"),bin.size=1e6,signal.col=c(\"red\",\"green\"),signal.cex=c(1,1),signal.pch=c(19,19),file=\"jpg\",dpi=300)<\/span><\/code><\/pre>\n<\/section>\n<p><span style=\"mso-spacerun:'yes';font-family:\u7b49\u7ebf;mso-bidi-font-family:'Times New Roman';font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><br \/><\/o:p><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.4227994227994228\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_0ZtkllicJ0lnjoblj3TiaM2ZUeTB1g.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqGFa34XpU4TkzPUSl5ibo6v29Ccj0ZtkllicJ0lnjoblj3TiaM2ZUeTB1g\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: \u7b49\u7ebf;font-size: 14px;\">\u63a5\u4e0b\u6765\u6211\u4eec\u8fd8\u53ef\u4ee5\u5bf9\u591a\u8868\u578b\u7684\u6570\u636e\u5c55\u793a\uff1a<\/span><span style=\"mso-spacerun:'yes';font-family:\u7b49\u7ebf;mso-bidi-font-family:'Times New Roman';font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"swift\"><code><span class=\"code-snippet_outer\">CMplot(pig60K, plot.type=\"m\", multracks=TRUE, threshold=c(1e-6,1e<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\"> 4),threshold.lty=c(1,2),threshold.lwd=c(1,1), threshold.col=c(\"black\",\"grey\"), amplify=TRUE,bin.size=1e6,chr.den.col=c(\"darkgreen\", \"yellow\", \"red\"), signal.col=c(\"red\",\"green\"),signal.cex=c(1,1),file=\"jpg\",memo=\"\",dpi=300)<\/span><\/code><\/pre>\n<\/section>\n<p><br \/><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.417027417027417\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_2Cp1TY2vHdjdekaPBGWErUCxdpDPvg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqpofjGcUGhJaVlDjISrDDjZtK2Cp1TY2vHdjdekaPBGWErUCxdpDPvg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u6211\u4eec\u8fd8\u53ef\u4ee5\u7ed8\u5236\u5708\u56fe\u4e5f\u5c31\u662fcircos\u5c55\u793a<\/span><\/p>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"objectivec\"><code><span class=\"code-snippet_outer\">CMplot(pig60K,plot.type=\"c\",chr.labels=paste(\"Chr\",c(1:18,\"X\"),sep=\"\"),r=0.4,cir.legend=TRUE,outward=FALSE,cir.legend.col=\"black\",cir.chr.h=1.3,chr.den.col=\"black\",file=\"jpg\",dpi=300)<\/span><\/code><\/pre>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.9927849927849928\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/10_Xcmj3V6BUwfESiaWatO9cTlIxSsKRg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAzRRponrmWezeJ06LYFcyFqoexWmEVicNgRJx6N6PS7czy219Xcmj3V6BUwfESiaWatO9cTlIxSsKRg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"693\" style=\"\" data-recalc-dims=\"1\"><\/p>\n<p><br \/><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u4e0a\u8ff0\u90fd\u662f\u4f7f\u7528\u81ea\u5e26\u7684\u793a\u4f8b\u6570\u636epig60K\uff0c\u5c0f\u679c\u8fd8\u662f\u559c\u6b22circos\u7684\u56fe\u7247\uff0c\u56fe\u7247\u597d\u770b\u7cbe\u7f8e\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u4e0a\u8ff0\u5c31\u662f\u6211\u4eec\u5bf9\u66fc\u54c8\u987f\u7684\u5b66\u4e60\uff0c\u5c0f\u4f19\u4f34\u6709\u6ca1\u6709\u5b66\u4f1a\u5462\uff0c\u53bb\u51c6\u5907\u4e00\u4e0b\u81ea\u5df1\u7684\u793a\u4f8b\u6570\u636e\uff0c\u7ed8\u5236\u597d\u770b\u7684\u66fc\u54c8\u987f\u56fe\u3002\u5c0f\u679c\u8981\u63d0\u9192\u5927\u5bb6\uff0c\u8981\u591a\u591a\u7406\u89e3\u4ee3\u7801\u53c2\u6570\u7684\u610f\u4e49\uff0c\u4e0a\u8ff0\u5c0f\u679c\u5df2\u7ecf\u6807\u6ce8\u4e86\u5f88\u591a\uff0c\u5c0f\u4f19\u4f34\u4eec\u53ef\u4ee5\u6839\u636e\u81ea\u5df1\u6570\u636e\u5185\u5bb9\u5957\u7528\u8fdb\u53bb\uff0c\u4f46\u662f\u4e5f\u4e0d\u8981\u5fd8\u8bb0\u662f\u4ec0\u4e48\u542b\u4e49\uff0c\u8fd9\u6837\u624d\u80fd\u7ed8\u5236\u51fa\u81ea\u5df1\u60f3\u8981\u7684\u66fc\u54c8\u987f\u56fe\uff01<\/span><span style=\"mso-spacerun:'yes';font-family:\u7b49\u7ebf;mso-bidi-font-family:'Times New Roman';font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><o:p><\/o:p><\/span><\/p>\n<p><span style=\"mso-spacerun:'yes';font-family:\u7b49\u7ebf;mso-bidi-font-family:'Times New Roman';font-size:10.5000pt;mso-font-kerning:1.0000pt;\"><br \/><\/span><\/p>\n<p><span style=\"font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u4e0b\u671f\u5c06\u4e3a\u4f60\u5e26\u6765\u66f4\u591aR\u8bed\u8a00\u7684\u9a9a\u64cd\u4f5c\u6280\u5de7\uff0c\u4ee5\u4e0b\u63a8\u8350\u7684\u662f\u4e00\u4e2a\u591a\u529f\u80fd\u7684\u751f\u4fe1\u5e73\u53f0\u3002<o:p><\/o:p><\/span><\/p>\n<p><span style=\"color: rgb(255, 0, 0);background: rgb(255, 255, 255);font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u4e91\u751f\u4fe1\u5e73\u53f0\u94fe\u63a5\uff1a<\/span><span style=\"color: rgb(255, 0, 0);background: rgb(255, 255, 255);text-decoration: underline;font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">http:\/\/www.biocloudservice.com\/home.html\u3002<\/span><span style=\"color: rgb(255, 0, 0);background: rgb(255, 255, 255);font-family: "Helvetica Neue", Helvetica, "Hiragino Sans GB", "Microsoft YaHei", Arial, sans-serif;font-size: 14px;\">\u3010\u70b9\u51fb\u6587\u672b\u9605\u8bfb\u539f\u6587\u67e5\u770b\u54e6\u3011<\/span><\/p>\n<p style=\"text-align: center;\"><br \/><\/p>\n<\/section>\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p><span style=\"color: rgb(217, 33, 66);\"><span style=\"font-size: 10.5pt;font-family: \u5fae\u8f6f\u96c5\u9ed1;\">\u5176\u4ed6<\/span><span style=\"font-size: 10.5pt;font-family: \u5fae\u8f6f\u96c5\u9ed1;\">\u76f8\u5173\u5206\u6790\u5185\u5bb9\uff0c\u4f8b\u5982\u9884\u6d4b\u80bf\u7624\u6837\u672c\u836f\u7269\u654f\u611f\u6027\u5206\u6790(http:\/\/www.biocloudservice.com\/712\/712.php),\u9884\u6d4b\u67d0\u6837\u672c\u4e9a\u578b\u5bf9\u514d\u75ab\u6cbb\u7597\u7684\u53cd\u5e94(http:\/\/www.biocloudservice.com\/292\/292.php)\uff0c\u5355\u6837\u672c\u5bcc\u96c6\u7b97\u6cd5\u5206\u6790\u514d\u75ab\u6d78\u6da6\u4e30\u5ea6(http:\/\/www.biocloudservice.com\/106\/106.php)\uff0c\u8ba1\u7b9764\u79cd\u514d\u75ab\u7ec6\u80de\u76f8\u5bf9\u542b\u91cf(http:\/\/www.biocloudservice.com\/107\/107.php)\u7b49\u90fd\u53ef\u4ee5\u7528\u672c\u516c\u53f8\u65b0\u5f00\u53d1\u7684\u96f6\u4ee3\u7801\u4e91\u5e73\u53f0\u751f\u4fe1\u5206\u6790\u5c0f\u5de5\u5177\uff0c\u4e00\u952e\u5b8c\u6210\u8be5\u5206\u6790\u5965\uff0c\u611f\u5174\u8da3\u7684\u5c0f\u4f19\u4f34\u6b22\u8fce\u6765\u5c1d\u8bd5\u5965\uff0c\u7f51\u5740\uff1ahttp:\/\/www.biocloudservice.com\/home.html\u3002<\/span><\/span><span 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