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hidden;border-radius: 460px;background-color: rgb(244, 171, 189);\">\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-bottom: 10px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 3px;border-color: rgb(244, 171, 189);padding: 18px;\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"text-align: justify;line-height: 1.8;letter-spacing: 1.5px;\">\n<p style=\"white-space: normal;\">\u5982\u679c\u60f3\u8981\u5f97\u5230\u7ec6\u80de\u5206\u5316\u8f68\u8ff9\uff0c\u5206\u5316\u7684\u65f6\u5e8f\u5206\u6790\uff0c\u7406\u8bba\u4e0a\u7684\u505a\u6cd5\u662f\u8bbe\u7f6e\u591a\u4e2a\u65f6\u95f4\u70b9\uff0c\u6bcf\u4e2a\u65f6\u95f4\u70b9\u53d6\u4e00\u6b21\u6837\uff0c\u8fdb\u884c\u6d4b\u5e8f\u4ee5\u53ca\u540e\u7eed\u7684\u5206\u6790\u3002\u4f46\u662f\u8fd9\u79cd\u65b9\u6cd5\u5f88\u96be\u505a\uff0c\u800c\u4e14\u8d39\u65f6\u8d39\u529b\u8d39\u94b1\u3002\u901a\u8fc7\u5355\u7ec6\u80de\u6d4b\u5e8f\u53ef\u4ee5\u4ece\u4e00\u7fa4\u7ec6\u80de\u4e2d\u5f97\u5230\u8f6c\u5f55\u77ac\u65f6\u5feb\u7167\uff0c\u53ef\u4ee5\u4ece\u4e2d\u63a8\u65ad\u51fa\u7ec6\u80de\u7684\u5206\u5316\u8f68\u8ff9\u3002\u8fd9\u79cd\u65b9\u6cd5\u56e0\u4e3a\u53ea\u53d6\u4e86\u4e00\u4e2a\u65f6\u95f4\u70b9\uff0c\u6240\u4ee5\u53eb\u505a\u4f2a\u65f6\u5e8f\u5206\u6790\u3002<br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.26666666666666666\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_QMgnapml3BwXNURCkOz1eJbubngFnA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPvLj02g8lkHm6EzIpzC2YIY5gQMgnapml3BwXNURCkOz1eJbubngFnA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-top: 10px;margin-bottom: 10px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 5%;flex: 0 0 auto;height: auto;align-self: flex-end;\">\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;align-self: flex-start;flex: 100 100 0%;border-style: solid;border-width: 1px;border-color: rgb(108, 62, 49);border-radius: 10px;overflow: hidden;padding: 10px;background-color: rgb(252, 230, 233);height: auto;margin-right: -12px;margin-left: -12px;\">\n<section style=\"justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgb(255, 255, 255);padding: 20px;border-radius: 10px;overflow: hidden;height: auto;\">\n<section style=\"text-align: justify;line-height: 1.8;letter-spacing: 1px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><strong>Monocle3\u662f<\/strong>\u505a\u4f2a\u65f6\u5e8f\u5206\u6790\u7684\u9996\u9009\u8f6f\u4ef6\u5305\u3002\u5176\u56e2\u961f\u53d1\u8868\u4e86\u4e00\u7bc7NATURE\u4e00\u7bc7NB\u4e24\u7bc7 NM\u3002\u7ecf\u8fc7\u4e24\u4e2a\u5927\u7248\u672c\u7684\u66f4\u65b0\uff0cmonocle3\u8fd8\u53ef\u4ee5\u505a\u7ec6\u80de\u7684\u964d\u7ef4\u548c\u5206\u7c7b\u7b49\u5206\u6790\u3002Monocle\u4f7f\u7528\u7b97\u6cd5\u6765\u5b66\u4e60\u6bcf\u4e2a\u7ec6\u80de\u4f5c\u4e3a\u52a8\u6001\u751f\u7269\u8fc7\u7a0b\u7684\u4e00\u90e8\u5206\u5fc5\u987b\u7ecf\u5386\u7684\u57fa\u56e0\u8868\u8fbe\u53d8\u5316\u5e8f\u5217\u3002\u4e00\u65e6\u4e86\u89e3\u4e86\u57fa\u56e0\u8868\u8fbe\u53d8\u5316\u7684\u603b\u4f53\u201c\u8f68\u8ff9\u201d\uff0cMonocle\u5c31\u53ef\u4ee5\u5c06\u6bcf\u4e2a\u7ec6\u80de\u653e\u7f6e\u5728\u8f68\u8ff9\u4e2d\u7684\u9002\u5f53\u4f4d\u7f6e\u3002\u7136\u540e\uff0c\u5c31\u53ef\u4ee5\u4f7f\u7528Monocle\u7684\u5dee\u5f02\u5206\u6790\u5de5\u5177\u5305\u6765\u5bfb\u627e\u5728\u8f68\u8ff9\u8fc7\u7a0b\u4e2d\u53d7\u8c03\u63a7\u7684\u57fa\u56e0\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;min-width: 5%;flex: 0 0 auto;height: auto;\">\n<section style=\"text-align: justify;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u63a5\u4e0b\u6765\u5c0f\u56fe\u5e26\u5927\u5bb6\u7528monocle3\u6765\u505a\u4f2a\u65f6\u5e8f\u5206\u6790\u3002<\/p>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPDPrt26RzZWfLn13ExG96J6ol4mDfsGWCA12FKNAmAzca1KpiaaC6pyw\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>\u4e00\u3001\u5b89\u88c5monocle3<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPpnvbMkq7WXX6UMv2c75MzmIH62rtwoDfxu3Tr5Nxr3B45Qwlxka2aQ\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.5;text-align: justify;letter-spacing: 1px;\">\n<p style=\"white-space: normal;\"><strong>\u9996\u5148\u5b89\u88c5Bioconductor, \u6253\u5f00Rstudio\u5e76\u4e14\u8fd0\u884c<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\"><span class=\"code-snippet__keyword\">if<\/span> (!requireNamespace(<span class=\"code-snippet__string\">\"BiocManager\"<\/span>, quietly = TRUE))<\/span><\/code><code><span class=\"code-snippet_outer\">install.packages(<span class=\"code-snippet__string\">\"BiocManager\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">BiocManager::install(version = <span class=\"code-snippet__string\">\"3.14\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.5;text-align: justify;letter-spacing: 1px;\">\n<p style=\"white-space: normal;\"><strong>\u63a5\u7740\u5b89\u88c5\u4e00\u4e9bBioconductor\u4e0d\u4f1a\u81ea\u52a8\u5b89\u88c5\u7684\u4f9d\u8d56<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">BiocManager::install(c(<span class=\"code-snippet__string\">'BiocGenerics'<\/span>, <span class=\"code-snippet__string\">'DelayedArray'<\/span>, <span class=\"code-snippet__string\">'DelayedMatrixStats'<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">                       <span class=\"code-snippet__string\">'limma'<\/span>, <span class=\"code-snippet__string\">'lme4'<\/span>, <span class=\"code-snippet__string\">'S4Vectors'<\/span>, <span class=\"code-snippet__string\">'SingleCellExperiment'<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">                       <span class=\"code-snippet__string\">'SummarizedExperiment'<\/span>, <span class=\"code-snippet__string\">'batchelor'<\/span>, <span class=\"code-snippet__string\">'HDF5Array'<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">                       <span class=\"code-snippet__string\">'terra'<\/span>, <span class=\"code-snippet__string\">'ggrastr'<\/span>))<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.5;text-align: justify;letter-spacing: 1px;\">\n<p style=\"white-space: normal;\"><strong>\u7136\u540e\u5b89\u88c5monocle3<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">install.packages(<span class=\"code-snippet__string\">\"devtools\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">devtools::install_github(<span class=\"code-snippet__string\">'cole-trapnell-lab\/monocle3'<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"margin: 10px 0%;text-align: left;justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;border-left: 5px solid rgb(242, 203, 203);border-bottom-left-radius: 0px;padding-left: 9px;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-start;\">\n<section style=\"margin: 2px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(110, 75, 36);line-height: 1.5;text-align: justify;letter-spacing: 1px;\">\n<p style=\"white-space: normal;\"><strong>\u901a\u5e38\u8fd9\u4f1a\u9700\u8981\u4e00\u5b9a\u7684\u65f6\u95f4\u3002<\/strong><\/p>\n<p style=\"white-space: normal;\"><strong>\u52a0\u8f7dmonocle3<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">library(monocle3)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPDPrt26RzZWfLn13ExG96J6ol4mDfsGWCA12FKNAmAzca1KpiaaC6pyw\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>\u4e8c\u3001\u6570\u636e\u52a0\u8f7d\u4e0e\u9884\u5904\u7406<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPpnvbMkq7WXX6UMv2c75MzmIH62rtwoDfxu3Tr5Nxr3B45Qwlxka2aQ\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u5c0f\u56fe\u8fd9\u91cc\u4f7f\u7528\u4e00\u4e2a\u79c0\u4e3d\u9690\u6746\u7ebf\u866b\u6570\u636e\u96c6\uff0c\u8fd9\u4e00\u6570\u636e\u96c6\u6765\u81eaPacker&Zhu\u7b49\u4eba\u3002\u4ed6\u4eec\u7684\u7814\u7a76\u5305\u62ec\u5bf9\u6574\u4e2a\u80da\u80ce\u53d1\u80b2\u8fc7\u7a0b\u7684\u65f6\u95f4\u5e8f\u5217\u5206\u6790\u3002\u6211\u4eec\u5c06\u4f7f\u7528\u6570\u636e\u7684\u4e00\u5c0f\u90e8\u5206\uff0c\u5176\u4e2d\u5305\u62ec\u5927\u591a\u6570\u795e\u7ecf\u5143\u7ec6\u80de\u3002<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">#\u52a0\u8f7d\u6570\u636e<\/span><\/code><code><span class=\"code-snippet_outer\">expression_matrix <- readRDS(url(<span class=\"code-snippet__string\">\"https:\/\/depts.washington.edu:\/trapnell-lab\/software\/monocle3\/celegans\/data\/packer_embryo_expression.rds\"<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\">cell_metadata <- readRDS(url(<span class=\"code-snippet__string\">\"https:\/\/depts.washington.edu:\/trapnell-lab\/software\/monocle3\/celegans\/data\/packer_embryo_colData.rds\"<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\">gene_annotation <- readRDS(url(<span class=\"code-snippet__string\">\"https:\/\/depts.washington.edu:\/trapnell-lab\/software\/monocle3\/celegans\/data\/packer_embryo_rowData.rds\"<\/span>))<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">cds <- new_cell_data_set(expression_matrix,<\/span><\/code><code><span class=\"code-snippet_outer\">                         cell_metadata = cell_metadata,<\/span><\/code><code><span class=\"code-snippet_outer\">                         gene_metadata = gene_annotation)<\/span><\/code><code><span class=\"code-snippet_outer\">#\u6570\u636e\u9884\u5904\u7406<\/span><\/code><code><span class=\"code-snippet_outer\">#\u6570\u636e\u9884\u5904\u7406<\/span><\/code><code><span class=\"code-snippet_outer\">cds <- preprocess_cds(cds, num_dim = <span class=\"code-snippet__number\">50<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">cds <- align_cds(cds, alignment_group = <span class=\"code-snippet__string\">\"batch\"<\/span>, residual_model_formula_str = <span class=\"code-snippet__string\">\"~ bg.300.loading + bg.400.loading + bg.500.1.loading + bg.500.2.loading + bg.r17.loading + bg.b01.loading + bg.b02.loading\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u4f7f\u7528alignment_group\u5bf9\u5176\u4e0d\u540c\u6279\u6b21\u7ec6\u80de\u3002bg.300\u7b49\u6bcf\u4e00\u5217\u5bf9\u5e94\u4e0e\u7ec6\u80de\u53ef\u80fd\u88ab\u6c61\u67d3\u7684\u4fe1\u53f7\uff0c\u5c06\u8fd9\u4e9b\u9879\u901a\u8fc7residual_model_formula_str\u4f20\u9012\u7ed9align_cds\uff0c\u5728\u540e\u7eed\u7684\u5904\u7406\u4e2d\u51cf\u53bb\u8fd9\u4e9b\u80cc\u666f\u4fe1\u53f7\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPDPrt26RzZWfLn13ExG96J6ol4mDfsGWCA12FKNAmAzca1KpiaaC6pyw\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>\u4e09\u3001\u964d\u4f4e\u7ef4\u5ea6\u5e76\u53ef\u89c6\u5316\u7ed3\u679c<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPpnvbMkq7WXX6UMv2c75MzmIH62rtwoDfxu3Tr5Nxr3B45Qwlxka2aQ\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u63a5\u4e0b\u6765\u53ef\u4ee5\u5bf9\u6570\u636e\u8fdb\u884c\u964d\u7ef4\uff0cmonocle3\u5efa\u8bae\u4f7f\u7528\u9ed8\u8ba4\u7684UMAP\u7b97\u6cd5\u964d\u7ef4\u3002<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">cds <- reduce_dimension(cds)<\/span><\/code><code><span class=\"code-snippet_outer\">plot_cells(cds, label_groups_by_cluster=FALSE,  color_cells_by = <span class=\"code-snippet__string\">\"cell.type\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.7666666666666667\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_9qsklEibFYHpcVQnEHCAcJaTXIvyVw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPpMf1Uiak6ysjdU4flK5stnXJQD9qsklEibFYHpcVQnEHCAcJaTXIvyVw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"text-align: center;white-space: normal;\"><strong><span style=\"font-size: 14px;\">Monocle\u91cd\u5efa\u4e86\u5e26\u6709\u8bb8\u591a\u5206\u652f\u7684\u8f68\u8ff9<\/span><\/strong><\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">\u4f7f\u7528plot_cells\uff08\uff09\u6765\u53ef\u89c6\u5316\u5355\u4e2a\u57fa\u56e0\u5982\u4f55\u6cbf\u8f68\u8ff9\u53d8\u5316\u3002\u8ba9\u6211\u4eec\u6765\u770b\u770b\u4e00\u4e9b\u5728\u7ea4\u6bdb\u795e\u7ecf\u5143\u4e2d\u5177\u6709\u6709\u8da3\u8868\u8fbe\u6a21\u5f0f\u7684\u57fa\u56e0\uff1a<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">ciliated_genes <- c(<span class=\"code-snippet__string\">\"che-1\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">                    <span class=\"code-snippet__string\">\"hlh-17\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">                    <span class=\"code-snippet__string\">\"nhr-6\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">                    <span class=\"code-snippet__string\">\"dmd-6\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">                    <span class=\"code-snippet__string\">\"ceh-36\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">                    <span class=\"code-snippet__string\">\"ham-1\"<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">plot_cells(cds,<\/span><\/code><code><span class=\"code-snippet_outer\">           genes=ciliated_genes,<\/span><\/code><code><span class=\"code-snippet_outer\">           label_cell_groups=FALSE,<\/span><\/code><code><span class=\"code-snippet_outer\">           show_trajectory_graph=FALSE)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.799074074074074\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_YBtUnYkLr53w2vdbstyR5hgYnl1ONw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLP0od6eicYlW4YI8Mz3GE24wng4YBtUnYkLr53w2vdbstyR5hgYnl1ONw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"text-align: center;line-height: 1.8;letter-spacing: 1.5px;font-size: 14px;\" powered-by=\"xiumi.us\">\n<p><strong>6\u4e2a\u57fa\u56e0\u7684\u8f68\u8ff9\u53d8\u5316<\/strong><\/p>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPDPrt26RzZWfLn13ExG96J6ol4mDfsGWCA12FKNAmAzca1KpiaaC6pyw\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>\u56db\u3001\u805a\u7c7b\u7ec6\u80de<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPpnvbMkq7WXX6UMv2c75MzmIH62rtwoDfxu3Tr5Nxr3B45Qwlxka2aQ\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u867d\u7136\u7ec6\u80de\u53ef\u4ee5\u4ece\u4e00\u79cd\u72b6\u6001\u6301\u7eed\u8fc7\u6e21\u5230\u4e0b\u4e00\u79cd\u72b6\u6001\uff0c\u5b83\u4eec\u4e4b\u95f4\u6ca1\u6709\u79bb\u6563\u7684\u8fb9\u754c\uff0c\u4f46\u662fMonocle\u5e76\u4e0d\u8ba4\u4e3a\u6570\u636e\u96c6\u4e2d\u7684\u6240\u6709\u7ec6\u80de\u90fd\u6765\u81ea\u4e00\u4e2a\u5171\u540c\u7684\u8f6c\u5f55\u201c\u7956\u5148\u201d\u3002Monocle\u80fd\u591f\u901a\u8fc7\u5176\u805a\u7c7b\u7a0b\u5e8f\u4e86\u89e3\u7ec6\u80de\u4f55\u65f6\u5e94\u8be5\u653e\u7f6e\u5728\u76f8\u540c\u7684\u8f68\u8ff9\u4e2d\uff0c\u800c\u4e0d\u662f\u653e\u7f6e\u5728\u4e0d\u540c\u7684\u8f68\u8ff9\u4e2d\u3002<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">cds <- cluster_cells(cds)<\/span><\/code><code><span class=\"code-snippet_outer\">plot_cells(cds, color_cells_by = <span class=\"code-snippet__string\">\"partition\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.7907407407407407\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_llhHR44eo85RibavdDdAKydncicY4w.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPtIvPKUk40b1B2D9UgwBDDMlcFTllhHR44eo85RibavdDdAKydncicY4w\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"text-align: center;white-space: normal;\"><strong><span style=\"font-size: 14px;\">\u5c06\u7ec6\u80de\u5206\u4e3a\u4e86\u56db\u7c7b<\/span><\/strong><\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<p style=\"white-space: normal;\">\u63a5\u4e0b\u6765\uff0c\u6211\u4eec\u5c06\u4f7f\u7528\u6700\u5173\u952e\u7684Learn_graph\uff08\uff09\u51fd\u6570\u5728\u6bcf\u4e2a\u5206\u533a\u4e2d\u62df\u5408\u4e00\u4e2a\u4e3b\u8981\u56fe\uff1a<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">cds <- learn_graph(cds)<\/span><\/code><code><span class=\"code-snippet_outer\">plot_cells(cds,<\/span><\/code><code><span class=\"code-snippet_outer\">           color_cells_by = <span class=\"code-snippet__string\">\"cell.type\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">           label_groups_by_cluster=FALSE,<\/span><\/code><code><span class=\"code-snippet_outer\">           label_leaves=FALSE,<\/span><\/code><code><span class=\"code-snippet_outer\">           label_branch_points=FALSE)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.7351851851851852\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_6jhxsNd2Ey8piaricqB4e136BYlFtg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPY6HlMRopG2TFicNIiaATzniaS855z6jhxsNd2Ey8piaricqB4e136BYlFtg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"font-size: 14px;line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"text-align: center;white-space: normal;\"><strong>\u8be5\u56fe\u5c06\u7528\u4e8e\u8bb8\u591a\u4e0b\u6e38\u6b65\u9aa4\uff0c\u5982\u5206\u652f\u5206\u6790\u548c\u5fae\u5206\u8868\u8fbe\u5f0f<\/strong><br \/><\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"display: flex;flex-flow: row;text-align: center;justify-content: center;margin-top: 10px;margin-bottom: 20px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPDPrt26RzZWfLn13ExG96J6ol4mDfsGWCA12FKNAmAzca1KpiaaC6pyw\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 auto;align-self: stretch;min-width: 10%;height: auto;background-color: rgb(254, 227, 229);box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(84, 54, 54);padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 17px;letter-spacing: 3px;\">\n<p style=\"white-space: normal;\"><strong>\u4e94\u3001\u7ec6\u80de\u4f2a\u65f6\u5e8f\u5206\u6790<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;align-self: stretch;height: auto;background-position: 0% 0%;background-repeat: repeat-y;background-size: 100%;background-attachment: scroll;background-image: url("https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPpnvbMkq7WXX6UMv2c75MzmIH62rtwoDfxu3Tr5Nxr3B45Qwlxka2aQ\/640?wx_fmt=png");\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 5px;height: 10px;vertical-align: top;overflow: hidden;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u4e3a\u4e86\u5c06\u7ec6\u80de\u6392\u5217\u6574\u9f50\uff0c\u6211\u4eec\u9700\u8981\u544a\u8bc9Monocle\u751f\u7269\u8fc7\u7a0b\u7684\u201c\u5f00\u59cb\u201d\u5728\u54ea\u91cc\u3002\u6211\u4eec\u901a\u8fc7\u9009\u62e9\u56fe\u4e2d\u6807\u8bb0\u4e3a\u8f68\u8ff9\u201c\u6839\u201d\u7684\u533a\u57df\u6765\u505a\u5230\u8fd9\u4e00\u70b9\u3002\u5728\u65f6\u95f4\u5e8f\u5217\u5b9e\u9a8c\u4e2d\uff0c\u8fd9\u901a\u5e38\u53ef\u4ee5\u901a\u8fc7\u5728UMAP\u7a7a\u95f4\u4e2d\u627e\u5230\u7531\u65e9\u671f\u65f6\u95f4\u70b9\u7684\u7ec6\u80de\u5360\u636e\u7684\u70b9\u6765\u5b9e\u73b0\uff1a<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">plot_cells(cds,<\/span><\/code><code><span class=\"code-snippet_outer\">           color_cells_by = <span class=\"code-snippet__string\">\"embryo.time.bin\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">           label_cell_groups=FALSE,<\/span><\/code><code><span class=\"code-snippet_outer\">           label_leaves=TRUE,<\/span><\/code><code><span class=\"code-snippet_outer\">           label_branch_points=TRUE,<\/span><\/code><code><span class=\"code-snippet_outer\">           graph_label_size=<span class=\"code-snippet__number\">1.5<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.8324074074074074\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_VWNBU81qlpcTonPmQbLuHeaP1lhzLw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPhT7ibcwHbKmPRm10daGE5bcsicVWNBU81qlpcTonPmQbLuHeaP1lhzLw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u9ed1\u7ebf\u663e\u793a\u4e86\u56fe\u7684\u7ed3\u6784\uff0c\u5e26\u6570\u5b57\u7684\u5706\u5708\u8868\u793a\u56fe\u5f62\u4e2d\u7684\u7279\u6b8a\u70b9\u3002\u6bcf\u7247\u53f6\u5b50\uff0c\u7528\u6d45\u7070\u8272\u5706\u5708\u8868\u793a\uff0c\u5bf9\u5e94\u4e8e\u8f68\u8ff9\u7684\u4e0d\u540c\u7ed3\u679c\uff08\u5373\u7ec6\u80de\u547d\u8fd0\uff09\u3002\u9ed1\u8272\u5706\u5708\u8868\u793a\u5206\u652f\u8282\u70b9\uff0c\u5176\u4e2d\u7ec6\u80de\u53ef\u4ee5\u4f20\u64ad\u5230\u51e0\u4e2a\u7ed3\u679c\u4e4b\u4e00\u3002<\/p>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;margin: 10px 0%;text-align: left;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;border-bottom: 3px solid rgb(242, 183, 183);border-bottom-right-radius: 0px;flex: 0 0 auto;align-self: flex-start;height: auto;padding-bottom: 3px;\">\n<section style=\"display: flex;flex-flow: row;text-align: justify;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;background-color: rgb(242, 183, 183);margin-right: 3px;flex: 0 0 auto;align-self: flex-end;min-width: 10%;height: auto;padding: 5px;\">\n<section style=\"color: rgb(255, 255, 255);text-align: center;\" powered-by=\"xiumi.us\">\n<p><strong>1<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;border-left: 4px solid rgb(242, 183, 183);border-bottom-left-radius: 0px;flex: 100 100 0%;align-self: stretch;height: auto;padding-top: 5px;padding-right: 10px;padding-left: 10px;\">\n<section style=\"color: rgb(181, 126, 121);letter-spacing: 4px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><strong>\u624b\u52a8\u9009\u53d6\u6839\u7ec6\u80de<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">cds <- order_cells(cds)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u73b0\u5728\u6211\u4eec\u5df2\u7ecf\u77e5\u9053\u4e86\u65e9\u671f\u7ec6\u80de\u7684\u4e0b\u843d\uff0c\u6211\u4eec\u53ef\u4ee5\u8c03\u7528order_cells\uff08\uff09\uff0c\u5b83\u5c06\u8ba1\u7b97\u6bcf\u4e2a\u7ec6\u80de\u5728\u4f2a\u65f6\u95f4\u5185\u7684\u4e0b\u843d\u3002\u4e3a\u4e86\u8fd9\u6837\u505a\uff0corder_cells\uff08\uff09\u9700\u8981\u60a8\u6307\u5b9a\u8f68\u8ff9\u56fe\u7684\u6839\u8282\u70b9\u3002\u5982\u679c\u60a8\u4e0d\u63d0\u4f9b\u5b83\u4eec\u4f5c\u4e3a\u53c2\u6570\uff0c\u5b83\u5c06\u542f\u52a8\u7528\u4e8e\u9009\u62e9\u4e00\u4e2a\u6216\u591a\u4e2a\u6839\u8282\u70b9\u7684\u56fe\u5f62\u7528\u6237\u754c\u9762\u3002<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.7\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_QxUuWRrkbFCkXGj4lxiaSZggKwmMqw.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPZviaSVWQFtNjq0tKG2GNxGdKVcQxUuWRrkbFCkXGj4lxiaSZggKwmMqw\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u7ed8\u5236\u7ec6\u80de\u5e76\u901a\u8fc7\u5047\u65f6\u95f4\u5bf9\u5176\u7740\u8272\u663e\u793a\u4e86\u5b83\u4eec\u662f\u5982\u4f55\u6392\u5217\u7684\uff1a<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">plot_cells(cds,<\/span><\/code><code><span class=\"code-snippet_outer\">           color_cells_by = <span class=\"code-snippet__string\">\"pseudotime\"<\/span>,<\/span><\/code><code><span class=\"code-snippet_outer\">           label_cell_groups=FALSE,<\/span><\/code><code><span class=\"code-snippet_outer\">           label_leaves=FALSE,<\/span><\/code><code><span class=\"code-snippet_outer\">           label_branch_points=FALSE,<\/span><\/code><code><span class=\"code-snippet_outer\">           graph_label_size=<span class=\"code-snippet__number\">1.5<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.7888888888888889\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_d0MRbia0GJO4TGPLdJc9eLhy01icug.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPCssEgI0iatGkicYbo9B45gWJpRibad0MRbia0GJO4TGPLdJc9eLhy01icug\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u6709\u4e9b\u5355\u5143\u683c\u662f\u7070\u8272\u7684\u3002\u8fd9\u610f\u5473\u7740\u5b83\u4eec\u6709\u65e0\u9650\u7684\u4f2a\u65f6\u95f4\uff0c\u56e0\u4e3a\u5b83\u4eec\u65e0\u6cd5\u4ece\u6839\u8282\u70b9\u8bbf\u95ee\u3002<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<section style=\"display: flex;flex-flow: row;margin: 10px 0%;text-align: left;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;border-bottom: 3px solid rgb(242, 183, 183);border-bottom-right-radius: 0px;flex: 0 0 auto;align-self: flex-start;height: auto;padding-bottom: 3px;\">\n<section style=\"display: flex;flex-flow: row;text-align: justify;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;background-color: rgb(242, 183, 183);margin-right: 3px;flex: 0 0 auto;align-self: flex-end;min-width: 10%;height: auto;padding: 5px;\">\n<section style=\"color: rgb(255, 255, 255);text-align: center;\" powered-by=\"xiumi.us\">\n<p><strong>2<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;border-left: 4px solid rgb(242, 183, 183);border-bottom-left-radius: 0px;flex: 100 100 0%;align-self: stretch;height: auto;padding-top: 5px;padding-right: 10px;padding-left: 10px;\">\n<section style=\"color: rgb(181, 126, 121);letter-spacing: 4px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><strong>\u901a\u8fc7\u4ee3\u7801\u62fe\u53d6\u6839\u8282\u70b9<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u901a\u5e38\u9700\u8981\u4ee5\u7f16\u7a0b\u65b9\u5f0f\u6307\u5b9a\u8f68\u8ff9\u7684\u6839\uff0c\u800c\u4e0d\u662f\u624b\u52a8\u62fe\u53d6\u3002\u4e0b\u9762\u7684\u51fd\u6570\u9996\u5148\u6839\u636e\u6700\u63a5\u8fd1\u7684\u8f68\u8ff9\u56fe\u8282\u70b9\u5bf9\u5355\u5143\u683c\u8fdb\u884c\u5206\u7ec4\u3002\u7136\u540e\uff0c\u5b83\u8ba1\u7b97\u6bcf\u4e2a\u8282\u70b9\u7684\u5355\u5143\u683c\u4e2d\u6765\u81ea\u6700\u65e9\u65f6\u95f4\u70b9\u7684\u90e8\u5206\u3002\u7136\u540e\uff0c\u5b83\u9009\u62e9\u65e9\u671f\u7ec6\u80de\u5360\u7528\u6700\u591a\u7684\u8282\u70b9\uff0c\u5e76\u5c06\u5176\u4f5c\u4e3a\u6839\u8fd4\u56de\u3002<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">get_earliest_principal_node <- function(cds, time_bin=<span class=\"code-snippet__string\">\"130-170\"<\/span>){<\/span><\/code><code><span class=\"code-snippet_outer\"> cell_ids <- which(colData(cds)[, <span class=\"code-snippet__string\">\"embryo.time.bin\"<\/span>] == time_bin)<\/span><\/code><code><span class=\"code-snippet_outer\"> <\/span><\/code><code><span class=\"code-snippet_outer\"> closest_vertex <-<\/span><\/code><code><span class=\"code-snippet_outer\"> cds@principal_graph_aux[[<span class=\"code-snippet__string\">\"UMAP\"<\/span>]]$pr_graph_cell_proj_closest_vertex<\/span><\/code><code><span class=\"code-snippet_outer\"> closest_vertex <- as.matrix(closest_vertex[colnames(cds), ])<\/span><\/code><code><span class=\"code-snippet_outer\"> root_pr_nodes <-<\/span><\/code><code><span class=\"code-snippet_outer\"> igraph::V(principal_graph(cds)[[<span class=\"code-snippet__string\">\"UMAP\"<\/span>]])$name[as.numeric(names<\/span><\/code><code><span class=\"code-snippet_outer\"> (which.max(table(closest_vertex[cell_ids,]))))]<\/span><\/code><code><span class=\"code-snippet_outer\"> <\/span><\/code><code><span class=\"code-snippet_outer\"> root_pr_nodes<\/span><\/code><code><span class=\"code-snippet_outer\">}<\/span><\/code><\/pre>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u901a\u8fc7root_pr_node\u53c2\u6570\u5c06\u7a0b\u5e8f\u9009\u62e9\u7684\u6839\u8282\u70b9\u4f20\u9012\u7ed9order_cells\uff08\uff09\u4f1a\u4ea7\u751f\uff1a<\/p>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" data-ratio=\"0.799074074074074\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_QibLMn6UuauBiaYVHql8wxxeEt4XIA.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLP1hUwRswr6ibJ6ia3XoJ7k6cXSfvHQibLMn6UuauBiaYVHql8wxxeEt4XIA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"display: flex;flex-flow: row;margin: 10px 0%;text-align: left;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;border-bottom: 3px solid rgb(242, 183, 183);border-bottom-right-radius: 0px;flex: 0 0 auto;align-self: flex-start;height: auto;padding-bottom: 3px;\">\n<section style=\"display: flex;flex-flow: row;text-align: justify;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;background-color: rgb(242, 183, 183);margin-right: 3px;flex: 0 0 auto;align-self: flex-end;min-width: 10%;height: auto;padding: 5px;\">\n<section style=\"color: rgb(255, 255, 255);text-align: center;\" powered-by=\"xiumi.us\">\n<p><strong>3<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: auto;border-left: 4px solid rgb(242, 183, 183);border-bottom-left-radius: 0px;flex: 100 100 0%;align-self: stretch;height: auto;padding-top: 5px;padding-right: 10px;padding-left: 10px;\">\n<section style=\"color: rgb(181, 126, 121);letter-spacing: 4px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\"><strong>\u751f\u62103D\u56fe<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"line-height: 1.8;letter-spacing: 1.5px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u6211\u4eec\u8fd8\u53ef\u4ee5\u751f\u62103D\u7684\u7ec6\u80de\u5206\u5316\u8f68\u8ff9\u56fe\u3002<\/p>\n<\/section>\n<section class=\"code-snippet__fix code-snippet__js\">\n<ul class=\"code-snippet__line-index code-snippet__js\">\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<li><\/li>\n<\/ul>\n<pre class=\"code-snippet__js\" data-lang=\"c\"><code><span class=\"code-snippet_outer\">cds_3d <- reduce_dimension(cds, max_components = <span class=\"code-snippet__number\">3<\/span>)<\/span><\/code><code><span class=\"code-snippet_outer\">cds_3d <- cluster_cells(cds_3d)<\/span><\/code><code><span class=\"code-snippet_outer\">cds_3d <- learn_graph(cds_3d)<\/span><\/code><code><span class=\"code-snippet_outer\">cds_3d <- order_cells(cds_3d, root_pr_nodes=get_earliest_principal_node(cds))<\/span><\/code><code><span class=\"code-snippet_outer\"><br \/><\/span><\/code><code><span class=\"code-snippet_outer\">cds_3d_plot_obj <- plot_cells_3d(cds_3d, color_cells_by=<span class=\"code-snippet__string\">\"partition\"<\/span>)<\/span><\/code><\/pre>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"0.7592592592592593\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/10_QdSKXfniaOcVwIeSe6I7Q7Ew9MhuAg.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPs3YwZXnVcgxLGkiawRMnA1mjXHQdSKXfniaOcVwIeSe6I7Q7Ew9MhuAg\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1080\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin-bottom: 10px;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 1px;border-color: rgb(176, 176, 176);padding: 7px;\">\n<section style=\"justify-content: flex-start;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgba(249, 238, 237, 0.5);padding: 18px;\">\n<section style=\"\" powered-by=\"xiumi.us\">\n<section style=\"text-align: justify;font-size: 14px;letter-spacing: 2px;line-height: 1.8;\">\n<p style=\"white-space: normal;\">\u5c0f\u56fe\u4eca\u5929\u7684\u8bb2\u89e3\u5c31\u5230\u8fd9\u91cc\u4e86~\u6211\u4eec\u4e0b\u671f\u89c1\u3002<\/p>\n<p style=\"white-space: normal;\">\u672c\u516c\u53f8\u5f00\u53d1\u7684\u4e91\u5e73\u53f0\u751f\u7269\u4fe1\u606f\u5206\u6790\u5de5\u5177\uff0c\u96f6\u4ee3\u7801\u5b8c\u6210\u5206\u6790\uff0c\u540c\u65f6\u4e5f\u6709\u8bb8\u591a\u751f\u7269\u5904\u7406\u7684\u597d\u7528\u5de5\u5177\u54e6~\u4e91\u5e73\u53f0\u7f51\u5740\uff1ahttp:\/\/www.biocloudservice.com\/home.html<\/p>\n<p style=\"white-space: normal;\"><br \/><\/p>\n<\/section>\n<\/section>\n<section style=\"text-align: justify;font-size: 14px;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;\">\u6b22\u8fce\u4f7f\u7528\uff1a\u4e91\u751f\u4fe1\u5e73\u53f0 ( http:\/\/www.biocloudservice.com\/home.html)<\/p>\n<\/section>\n<section style=\"transform: scale(0.5);transform-origin: center center;margin-top: -65px;margin-bottom: -65px;\" powered-by=\"xiumi.us\">\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-ratio=\"1\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/11_Bk8Hn3YR4fTn9nt5mVpJIe1diadCeg.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/2wJ7bWfS0QsK3bt5BgR7soicwrXZEfsLPvsZ1NLJNWSg52AMibMuT2an6eXBk8Hn3YR4fTn9nt5mVpJIe1diadCeg\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"258\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"min-height: 40px;margin: 10px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"width: 100%;margin-right: auto;margin-bottom: -10px;margin-left: auto;\">\n<table width=\"100%\">\n<tbody>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:73.classicTable1:0\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:73.classicTable1:0.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;background-color: rgb(249, 174, 165);padding: 10px 0px;\" width=\"96.3700%\">\n<section style=\"line-height: 1;text-align: center;font-size: 17px;color: rgb(255, 255, 255);letter-spacing: 5px;\" powered-by=\"xiumi.us\">\n<p><strong>\u5f80\u671f\u63a8\u8350<\/strong><\/p>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:73.classicTable1:1\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:73.classicTable1:1.td@@0\" style=\"border-top: 0px none rgb(62, 62, 62);border-right: 0px none rgb(62, 62, 62);border-left: 0px none rgb(62, 62, 62);border-bottom-color: rgb(202, 198, 198);border-bottom-style: dashed;background-color: rgb(247, 247, 247);padding-right: 5px;padding-left: 5px;\" width=\"96.3700%\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: middle;border-width: 0px;align-self: center;flex: 0 0 auto;\">\n<section style=\"font-size: 14px;letter-spacing: 1px;\" powered-by=\"xiumi.us\">\n<p><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247484863&idx=1&sn=28a92146a8b2f04d0d5dc32bed20b527&chksm=c1b17842f6c6f154ac96a34752f22788d3ea4bf52a009dc72bd61f23b56b74a89eb72355e4d8&scene=21#wechat_redirect\" textvalue=\"\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u2014\u5982\u4f55\u4f7f\u7528GWAS summary\u6570\u636e\u5e93\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u2014\u5982\u4f55\u4f7f\u7528GWAS summary\u6570\u636e\u5e93<\/a><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:73.classicTable1:2\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:73.classicTable1:2.td@@0\" style=\"border-top: 0px none rgb(62, 62, 62);border-right: 0px none rgb(62, 62, 62);border-left: 0px none rgb(62, 62, 62);border-bottom-color: rgb(202, 198, 198);border-bottom-style: dashed;background-color: rgb(247, 247, 247);padding-right: 5px;padding-left: 5px;\" width=\"96.3700%\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: middle;border-width: 0px;align-self: center;flex: 0 0 auto;\">\n<section style=\"font-size: 14px;letter-spacing: 1px;\" powered-by=\"xiumi.us\">\n<p><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247484862&idx=1&sn=1b340dcdd7b13099951666fd6be2e017&chksm=c1b17843f6c6f155f7c2e8a64a4761a066e4e4deb7e9c39ebf938452f6d03ee21a6a4339f2c7&scene=21#wechat_redirect\" textvalue=\"\u8d85\u8be6\u7ec6\uff0c\u5c0f\u56fe\u5e26\u4f60\u7528beeswarm\u753b\u4f18\u96c5\u7684\u6563\u70b9\u871c\u8702\u56fe\u5206\u6790\u57fa\u56e0\u4e0e\u4e34\u5e8a\u76f8\u5173\u6027\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u8d85\u8be6\u7ec6\uff0c\u5c0f\u56fe\u5e26\u4f60\u7528beeswarm\u753b\u4f18\u96c5\u7684\u6563\u70b9\u871c\u8702\u56fe\u5206\u6790\u57fa\u56e0\u4e0e\u4e34\u5e8a\u76f8\u5173\u6027<\/a><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:73.classicTable1:3\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:73.classicTable1:3.td@@0\" style=\"border-top: 0px none rgb(62, 62, 62);border-right: 0px none rgb(62, 62, 62);border-left: 0px none rgb(62, 62, 62);border-bottom-color: rgb(202, 198, 198);border-bottom-style: dashed;background-color: rgb(247, 247, 247);padding-right: 5px;padding-left: 5px;\" width=\"96.3700%\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: middle;border-width: 0px;align-self: center;flex: 0 0 auto;\">\n<section style=\"font-size: 14px;letter-spacing: 1px;\" powered-by=\"xiumi.us\">\n<p><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzkxODUxNDgzNA==&mid=2247484842&idx=1&sn=31983adde6a9dbeca752145768349898&chksm=c1b17857f6c6f1411f96f6ba84709b47f8a015024df1bfa821da455ad202c672f60a3226cf1b&scene=21#wechat_redirect\" textvalue=\"\u542c\u8bf4\u4f60\u8fd8\u5728\u56f0\u60d1SCI\u914d\u8272\u95ee\u9898\uff1f\u5c0f\u56fe\u4e00\u6587\u8ba9\u4f60\u5b66\u4f1aSCI\u9876\u520a\u7684\u914d\u8272\u65b9\u6848\uff01\uff01\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u542c\u8bf4\u4f60\u8fd8\u5728\u56f0\u60d1SCI\u914d\u8272\u95ee\u9898\uff1f\u5c0f\u56fe\u4e00\u6587\u8ba9\u4f60\u5b66\u4f1aSCI\u9876\u520a\u7684\u914d\u8272\u65b9\u6848\uff01\uff01\uff01<\/a><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\"><br \/><\/p>\n<p style=\"white-space: normal;\" powered-by=\"xiumi.us\">\ud83d\udc47\u70b9\u51fb\u9605\u8bfb\u539f\u6587\u8fdb\u5165\u7f51\u5740<\/p>\n<\/section>\n<p style=\"display: none;margin-bottom: 24px;\"><mp-style-type data-value=\"3\"><\/mp-style-type><\/p>\n<div class=\"msg_source_url\"><a href=\"http:\/\/www.biocloudservice.com\/home.html\" target=\"_blank\" rel=\"noopener\">\u9605\u8bfb\u539f\u6587<\/a><\/div>\n<p><\/content><\/p>\n<div class=\"msg_source_url\"><a href=\"http:\/\/www.biocloudservice.com\/home.html\" target=\"_blank\" rel=\"noopener\">\u9605\u8bfb\u539f\u6587<\/a><\/div>\n<\/div>\n<p><\/body><br \/>\n<\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u62df\u65f6\u5e8f\u5206\u6790\u4e0d\u4f1a\u505a\uff1fR\u5305Monocle3\u6765\u89e3\u51b3 \u5c0f\u56fe  \u751f\u4fe1\u679c  202 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/59651"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=59651"}],"version-history":[{"count":1,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/59651\/revisions"}],"predecessor-version":[{"id":59663,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/59651\/revisions\/59663"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=59651"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=59651"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=59651"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}