{"id":59976,"date":"2024-06-17T10:38:49","date_gmt":"2024-06-17T02:38:49","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=59976"},"modified":"2024-06-17T10:38:49","modified_gmt":"2024-06-17T02:38:49","slug":"%e4%b8%ad%e5%8c%bb%e8%8d%af%e7%bd%91%e7%bb%9c%e8%8d%af%e7%90%86%e5%ad%a6%e6%80%a7%e4%bb%b7%e6%af%94%e4%b9%8b%e7%8e%8b%ef%bc%81%e5%90%8c%e6%b5%8e%e5%a4%a7%e5%ad%a6%e5%8d%97%e4%ba%ac%e4%b8%ad","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=59976","title":{"rendered":"\u4e2d\u533b\u836f+\u7f51\u7edc\u836f\u7406\u5b66=\u6027\u4ef7\u6bd4\u4e4b\u738b\uff01\u540c\u6d4e\u5927\u5b66+\u5357\u4eac\u4e2d\u533b\u836f\u5927\u5b66\u5f3a\u5f3a\u8054\u5408\u53d1\u8868\u65b0\u4f5c\uff01\u7ecf\u5178\u901a\u8def+\u5e72\u6e7f\u7ed3\u5408\u5b9e\u73b0\u8f7b\u677e\u53d1\u6587\uff01"},"content":{"rendered":"


\n
\n<\/title><br \/>\n<meta charset=\"utf-8\"><br \/>\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,maximum-scale=1.0,user-scalable=0,viewport-fit=cover\"><\/p>\n<style>\n*{margin:0;padding:0}html{-ms-text-size-adjust:100%;-webkit-text-size-adjust:100%;line-height:1.6}img{z-index:999;position:relative;max-width:100%;margin:10px 0;}body{letter-spacing:.034em}h1,h2,h3,h4,h5,h6{font-weight:400;font-size:16px}a{color:#576b95;text-decoration:none;-webkit-tap-highlight-color:rgba(0,0,0,0)}td,th{word-wrap:break-word;padding:5px 10px;border:1px solid #DDD;}table{margin-bottom:10px;border-collapse:collapse;display:table;width:100%!important;}.appmsg_skin_default .rich_media_area_primary{background-color:#fff}.appmsg_skin_default .rich_media_area_primary .weui-loadmore_line .weui-loadmore__tips{background-color:#fff}.rich_media_area_primary{padding:20px 16px 12px;background-color:#fafafa}@media (max-width:375px){.rich_media_area_primary{padding:20px 60px 15px 60px}.rich_media_area_extra{padding:0 60px 21px 60px}}@media (min-width:1024px){.rich_media_area_primary_inner,.rich_media_area_extra_inner,body{max-width:677px;margin-left:auto;margin-right:auto}.rich_media_area_primary{padding-top:32px}}.rich_media{padding:20px;overflow:hidden;}.appmsg_skin_default .rich_media_area_primary{background-color:#fff}.appmsg_skin_default .rich_media_area_primary .weui-loadmore_line .weui-loadmore__tips{background-color:#fff}@media screen and (min-width:1024px){.rich_media_area_primary_inner,.rich_media_area_extra_inner{max-width:677px;margin-left:auto;margin-right:auto}.rich_media_area_primary{padding-top:32px}}.rich_media_content{overflow:hidden;color:#333;font-size:17px;word-wrap:break-word;-webkit-hyphens:auto;-ms-hyphens:auto;hyphens:auto;text-align:justify;position:relative;z-index:0}.rich_media_content *{max-width:100%!important;box-sizing:border-box!important;-webkit-box-sizing:border-box!important;word-wrap:break-word!important}.rich_media_content p{clear:both;min-height:1em}.rich_media_content em{font-style:italic}.rich_media_content fieldset{min-width:0}.rich_media_content .list-paddingleft-1,.rich_media_content .list-paddingleft-2,.rich_media_content .list-paddingleft-3{padding-left:2.2em}.rich_media_content .list-paddingleft-1 .list-paddingleft-2,.rich_media_content .list-paddingleft-2 .list-paddingleft-2,.rich_media_content .list-paddingleft-3 .list-paddingleft-2{padding-left:30px}.rich_media_content .list-paddingleft-1{padding-left:1.2em}.rich_media_content .list-paddingleft-3{padding-left:3.2em}.rich_media_content .code-snippet,.rich_media_content .code-snippet__fix{max-width:1000%!important}.rich_media_content .code-snippet *,.rich_media_content .code-snippet__fix *{max-width:1000%!important}.rich_media_title{font-size:22px;line-height:1.4;margin-bottom:13px;padding-bottom:13px;border-bottom:1px solid #e7e7eb;}@supports(-webkit-overflow-scrolling:touch){.rich_media_title{font-weight:700}}.rich_media_meta{display:inline-block;vertical-align:middle;padding:0 0 10px 0;font-size:15px;-webkit-tap-highlight-color:rgba(0,0,0,0)}.rich_media_meta.icon_appmsg_tag{margin-right:0px}.rich_media_meta.meta_tag_text{margin-right:0}.rich_media_meta_list em{font-style:normal}.rich_media_meta_text{color:#a5a5a5;}p{margin:0;}.msgBox{margin-top:20px;padding-top:20px;padding-left:50px;overflow:hidden;border-top:2px dashed #09a2ff;}.msg{padding-top:7px;clear:both;}.msgBody{float:right;width:100%;margin-left:55px;padding-bottom:15px;border-bottom:1px dashed #e0e0e0;}.userHeadImg{float:left;margin-left:-50px;}.userHeadImg img{width:40px;height:40px;margin-right:10px;border-radius:3px;}.userName{color:#888888;line-height:24px;font-size:14px;margin:5px 0 5px 0;height:24px;}.replyBody,.autherBody{color:#565656;font-size:15px;}.replyIcon{border-left:4px solid #33ab01;margin-right:5px;}.ad{text-decoration:none;color:#d6d4d4;font-size:12px;}.msgBodyReply{padding-top:5px;}.userName span{float:right;color:#afafaf;font-size:14px;}code{text-align:left;font-size:14px;display:block;white-space:pre;display:-webkit-box;display:-webkit-flex;display:flex;position:relative;}.code-snippet__fix{font-size:14px;margin:10px 0;display:block;color:#333;position:relative;background-color:rgba(0,0,0,0.03);border:1px solid #f0f0f0;border-radius:2px;display:-webkit-box;display:-webkit-flex;display:flex;padding-left:25px;line-height:26px}.code-snippet__fix code{text-align:left;font-size:14px;display:block;white-space:pre;display:-webkit-box;display:-webkit-flex;display:flex;position:relative;font-family:Consolas,\"Liberation Mono\",Menlo,Courier,monospace}.code-snippet__comment,.code-snippet__quote{color:#afafaf;font-style:italic}.code-snippet__keyword,.code-snippet__selector-tag,.code-snippet__subst{color:#ca7d37}.code-snippet__number,.code-snippet__literal,.code-snippet__variable,.code-snippet__template-variable,.code-snippet__tag .code-snippet__attr{color:#0e9ce5}.code-snippet__string,.code-snippet__doctag{color:#d14}.code-snippet__title,.code-snippet__section,.code-snippet__selector-id{color:#d14}.code-snippet__subst{font-weight:normal}.code-snippet__type,.code-snippet__class .code-snippet__title{color:#0e9ce5}.code-snippet__tag,.code-snippet__name,.code-snippet__attribute{color:#0e9ce5;font-weight:normal}.code-snippet__regexp,.code-snippet__link{color:#ca7d37}.code-snippet__symbol,.code-snippet__bullet{color:#d14}.code-snippet__built_in,.code-snippet__builtin-name{color:#ca7d37}.code-snippet__meta{color:#afafaf}.code-snippet__deletion{background:#fdd}.code-snippet__addition{background:#dfd}.code-snippet__emphasis{font-style:italic}.code-snippet__strong{font-weight:bold}.account_avatar{width:40px;height:40px;padding:0;}.account_info{display:-webkit-box;display:-webkit-flex;display:flex;-webkit-box-align:center;-webkit-align-items:center;padding:20px 0;align-items:center}.flex_bd{padding-left:14px;}.account_nickname{display:inline-block;vertical-align:middle;line-height:1.2;color:#576b95;font-size:14px}.account_desc{overflow:hidden;text-overflow:ellipsis;display:-webkit-box;-webkit-box-orient:vertical;-webkit-line-clamp:1;color:rgba(0,0,0,0.3);font-size:14px;line-height:1.2;padding-top:.4em}.msg_source_url{text-align:left;word-break:break-all;margin-top:20px;}.msg_source_url a{padding-right:10px;}.msg_source_url .url_text{color:#a8a8a8;}.video-desc{font-size:14px;margin-top:15px;color:#6c6c6c;}.msg_source_url{text-align:left;}.original_primary_card_tips{color:rgba(0,0,0,0.3);line-height:1.4;font-size:15px;}.weui-flex__item{margin-bottom:20px;padding:20px 16px;margin-top:16px;line-height:1.4;align-items:center;background-color:#f7f7f7;border-radius:8px;position:relative;}.original_primary_desc{color:rgba(0,0,0,0.5);font-size:14px;padding-top:4px;width:auto;overflow:hidden;text-overflow:ellipsis;}.msgBodyReplyList{border-top:1px solid #e1e1e1;margin-top:10px;}.msgBodyReplyListTop{border-top:0;}.reply_like_num{float:right;font-size:14px;color:#c7c7c7;}.msgData{margin-top:20px;color:#626262;}.msgData span{font-size:14px;padding-right:15px;}.msgData .likes{float:right;padding-right:0;}.js_text_content p{font-size:18px;}.rich_media_meta_link{font-size:15px;}blockquote {padding-left: 10px;border-left: 3px solid #dbdbdb;color: rgba(0,0,0,0.5);font-size: 15px;padding-top: 4px;margin: 1em 0;}.video_iframe{width:500px;height:400px;}.blockquote_info{color:#b5b5b5;margin-top:10px;}#copyright_logo{color:#bdbdbd;}.rich_media_meta_list{margin-bottom:10px;}.reprint{background:#efefef;border-radius:5px;padding:8px;color:#1f1f1f;}.reprint a{word-break:break-all;}.topic{color:#8e8e8e;background:#f7f7f7;border-radius:5px;padding:10px 8px;}.topic a{padding-right:5px;}.topic p{margin-bottom:5px;}\n<\/style>\n<link href=\"https:\/\/www.juyifx.cn\/config\/css\/wxArticle.css\" rel=\"stylesheet\"\/>\n<\/head><script>\nvar data={\"mp\":\"\u751f\u4fe1\u679c\",\"title\":\"\u4e2d\u533b\u836f+\u7f51\u7edc\u836f\u7406\u5b66=\u6027\u4ef7\u6bd4\u4e4b\u738b\uff01\u540c\u6d4e\u5927\u5b66+\u5357\u4eac\u4e2d\u533b\u836f\u5927\u5b66\u5f3a\u5f3a\u8054\u5408\u53d1\u8868\u65b0\u4f5c\uff01\u7ecf\u5178\u901a\u8def+\u5e72\u6e7f\u7ed3\u5408\u5b9e\u73b0\u8f7b\u677e\u53d1\u6587\uff01\",\"time\":\"2024-03-04 19:00:39\",\"timeStamp\":\"1709550039\"};\n<\/script><br \/>\n<body><\/p>\n<div class=\"rich_media\">\n<h1 class=\"rich_media_title\" id=\"activity-name\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247500787&idx=1&sn=56180e49b869d1045b0c48793fc70b5d&chksm=cf7f5336f808da20d6d5e30b978172e4d0fa8e366306a7746344bfd0bc06823bae2027e7015f#rd\" target=\"_blank\" rel=\"noopener\">\u4e2d\u533b\u836f+\u7f51\u7edc\u836f\u7406\u5b66=\u6027\u4ef7\u6bd4\u4e4b\u738b\uff01\u540c\u6d4e\u5927\u5b66+\u5357\u4eac\u4e2d\u533b\u836f\u5927\u5b66\u5f3a\u5f3a\u8054\u5408\u53d1\u8868\u65b0\u4f5c\uff01\u7ecf\u5178\u901a\u8def+\u5e72\u6e7f\u7ed3\u5408\u5b9e\u73b0\u8f7b\u677e\u53d1\u6587\uff01<\/a><\/h1>\n<div id=\"meta_content\" class=\"rich_media_meta_list\"><span class=\"rich_media_meta rich_media_meta_text\">\u5c0f\u9014  <\/span><span class=\"rich_media_meta rich_media_meta_nickname\" id=\"profileBt\"><a href=\"javascript:void(0);\" class=\"wx_tap_link js_wx_tap_highlight weui-wa-hotarea\" id=\"js_name\">\u751f\u4fe1\u679c  <\/a><\/span><em id=\"publish_time\" class=\"rich_media_meta rich_media_meta_text\">2024-03-04 19:00:39<\/em><\/div>\n<p><content><\/p>\n<div class=\"reprint\">\n<p>\u8f6c\u81ea\u516c\u4f17\u53f7\uff1a\u751f\u4fe1\u8def<br \/><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzk0MDQ2MTU0Mg==&mid=2247493153&idx=1&sn=f9e74c143193c0c6574cfdc6f4647859\" target=\"_blank\" title=\"\u9605\u8bfb\u539f\u6587\" rel=\"noopener\">http:\/\/mp.weixin.qq.com\/s?__biz=Mzk0MDQ2MTU0Mg==&mid=2247493153&idx=1&sn=f9e74c143193c0c6574cfdc6f4647859<\/a><\/p>\n<\/div>\n<p style=\"text-align: center;\" data-mpa-powered-by=\"yiban.io\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-imgfileid=\"100015224\" data-ratio=\"0.2222222222222222\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/1_r0Gd7iaumIGMiaia97aHFV15nrpdzw-183.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAxQW8Zek7Noib2uBhB3ZE3yMxI2Hfic7cGTdPYiacicg47jficdr5BVr0Gd7iaumIGMiaia97aHFV15nrpdzw\/640?wx_fmt=png&from=appmsg'\" data-type=\"png\" data-w=\"900\" style=\"\" data-recalc-dims=\"1\" \/><\/p>\n<section style=\"text-align: left;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-family: \u5b8b\u4f53;font-size: 12pt;text-indent: 0em;letter-spacing: 0.034em;\">\u4e2d\u533b\u836f\u7684\u5c0f\u4f19\u4f34\u901a\u5e38\u4f1a\u642d\u4e0a\u7f51\u7edc\u836f\u7406\u5b66\u8fd9\u8d9f\u5c0f\u8f66\uff0c\u6027\u4ef7\u6bd4\u9ad8\uff0c\u7b80\u5355\u6613\u5b66\uff0c\u53ef\u89c6\u5316\u6548\u679c\u597d\u3002\u7f51\u7edc\u836f\u7406\u5b66\u642d\u914d\u4f53\u5916\u5b9e\u9a8c\u6216\u4f53\u5185\u5b9e\u9a8c\uff0c5\u5206\u4ee5\u4e0a\u7684\u6587\u7ae0\u53ef\u8c13\u662f\u624b\u5230\u64d2\u6765\u3002\u5c24\u5176\u662f\u5728\u56fd\u5bb6\u6276\u6301\u4e2d\u533b\u836f\u7684\u5927\u597d\u65f6\u673a\u4e0b\uff0c\u6bcf\u4e00\u4e2a\u79d1\u7814\u5c0f\u4f19\u4f34\u90fd\u8981\u8d76\u7d27\u6293\u4f4f\u673a\u4f1a\uff01<\/span><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;font-family:Times New Roman;mso-ascii-font-family:Times New Roman;mso-fareast-font-family:\u5b8b\u4f53;mso-bidi-font-family:\u5b8b\u4f53;font-variant:normal;text-transform:none;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100009493\" data-ratio=\"0.8459530026109661\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_GdcmxQ3ib7aspXcWgHnwdhJdOpwQZQ.jpg?resize=166%2C140\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/hud5kpqc1LT7ZGomgAumVjdf8p9sw4sXzpfkT2e97yDCOuc1VGNm3qhhyGdcmxQ3ib7aspXcWgHnwdhJdOpwQZQ\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"383\" height=\"140 .99996948242188\" width=\"166 .66998291015625\" data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"text-align: left;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;font-family:\u5b8b\u4f53;mso-ascii-font-family:Times New Roman;mso-bidi-font-family:\u5b8b\u4f53;font-variant:normal;text-transform:none;\">\u4eca\u5929\u8fd9\u7bc7\u6587\u7ae0\u91c7\u7528\u4e86\u7f51\u7edc\u836f\u7406\u5b66\u548c\u4f53\u5916\u5b9e\u9a8c\u7684\u7ed3\u5408\uff0c\u7814\u7a76\u832f\u82d3\u7684\u4e3b\u8981\u6d3b\u6027\u6210\u5206\u5728\u6cbb\u7597\u7cd6\u5c3f\u75c5\u6e83\u75a1\u65b9\u9762\u7684\u6f5c\u5728\u6cbb\u7597\u4f5c\u7528\u3002\u7814\u7a76\u56e2\u961f\u5728\u6b64\u524d\u62a5\u9053\u4e86\u542b\u6709\u832f\u82d3\u4e09\u841c\u7c7b\u5316\u5408\u7269\u7684\u900f\u660e\u8d28\u9178\u6c34\u51dd\u80f6\u53ef\u4ee5\u663e\u8457\u52a0\u901f\u7cd6\u5c3f\u75c5\u4f24\u53e3\u6108\u5408\uff0c\u5177\u6709\u6297\u708e\u4f5c\u7528\u3002\u672c\u6587\u901a\u8fc7\u7f51\u7edc\u836f\u7406\u5b66\u5206\u6790\u4e86\u832f\u82d3\u548c\u7cd6\u5c3f\u75c5\u6e83\u75a1\u7684\u4ea4\u96c6\u9776\u70b9\uff0c\u4f7f\u7528\u4eba\u8110\u9759\u8109\u8840\u7ba1\u5185\u76ae\u7ec6\u80de\u548c\u4eba\u9ad3\u7cfb\u767d\u8840\u75c5\u5355\u6838\u7ec6\u80de\u8fdb\u884c\u4e86\u4f53\u5916\u5b9e\u9a8c\u3002<\/span><\/section>\n<section style=\"text-align: left;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;font-family:\u5b8b\u4f53;mso-ascii-font-family:Times New Roman;font-variant:normal;text-transform:none;\">\u672c\u6587\u4ec5\u9760\u4f53\u5916\u5b9e\u9a8c\u8fdb\u884c\u4e86\u9a8c\u8bc1\uff0c\u4f46\u7814\u7a76\u601d\u8def\u8f83\u4e3a\u5b8c\u6574\u3002\u60f3\u8981\u5feb\u901f\u53d1\u8868SCI\u7684\u5c0f\u4f19\u4f34\u4eec\u53ef\u4ee5\u501f\u9274\uff0c\u6362\u4e2a\u4e2d\u836f\u6216\u6362\u4e2a\u75be\u75c5\u4e5f\u662f\u540c\u6837\u7684\u5957\u8def\uff01\u5145\u5206\u5229\u7528\u7f51\u7edc\u836f\u7406\u5b66\u7b49\u751f\u4fe1\u5de5\u5177\u52a9\u653b\u5b9e\u9a8c\u7814\u7a76\uff0c\u7f29\u77ed\u53d1\u6587\u5468\u671f\uff0c\u5b9e\u73b0\u53d1\u6587\u81ea\u7531\uff01<\/span><\/section>\n<p style=\"outline: 0px;font-family: system-ui, -apple-system, "system-ui", "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);visibility: visible;margin-bottom: 24px;\"><span style=\"outline: 0px;color: rgb(0, 82, 255);visibility: visible;\"><strong style=\"outline: 0px;visibility: visible;\"><span style=\"outline: 0px;font-size: 16px;visibility: visible;\">\uff08PS\uff1a\u6ca1\u6709\u601d\u8def\u3001\u4e0d\u77e5\u9053\u600e\u4e48\u521b\u65b0\u7684\u5b9d\u5b50\u4eec\uff0c\u8bb0\u5f97\u6765\u627e\u5c0f\u9014\u54e6\uff0c\u8d85\u591a\u4e2a\u6027\u5316\u601d\u8def\u7b49\u4f60\u6765\u62ff\uff01\uff09<\/span><\/strong><\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-imgfileid=\"100017016\" data-ratio=\"1\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_B2jkicacLzPjw4xMSqVvoucZjonVDA-21.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAxVYfSsM0wdf9d3RpNiaTcHohxPNEVs2VFhPMukpU8lchxrvcB2jkicacLzPjw4xMSqVvoucZjonVDA\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"430\" style=\"width: 177px;height: 177px;\" data-recalc-dims=\"1\" \/><\/p>\n<section style=\"text-align: left;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><o:page><\/o:page><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-family:\u7b49\u7ebf;mso-ascii-font-family:\u7b49\u7ebf;mso-fareast-font-family:\u7b49\u7ebf;font-variant:normal;text-transform:none;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100009494\" data-ratio=\"0.44976076555023925\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_sZH55PU5BiaBaicpoHMnluc9BLoiaA.png?resize=553%2C249\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LT7ZGomgAumVjdf8p9sw4sXNcjoCWoibFPrMPPBNKNTNt3EfHQlsZH55PU5BiaBaicpoHMnluc9BLoiaA\/640?wx_fmt=png'\" data-type=\"png\" data-w=\"1045\" height=\"249 .07000732421875\" width=\"553 .739990234375\" data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"margin-top: 0pt;margin-bottom: 0pt;text-align: justify;font-size: 10.5pt;font-family: \u7b49\u7ebf;font-weight: normal;margin-left: 21pt;line-height: 150%;text-indent: 0em;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 16px;\">\u9898\u76ee\uff1a\u832f\u82d3\u7684\u751f\u7269\u6d3b\u6027\u4e09\u841c\u7c7b\u5316\u5408\u7269\u901a\u8fc7\u8c03\u8282PI3K-AKT\u4fe1\u53f7\u901a\u8def\u6cbb\u7597\u7cd6\u5c3f\u75c5\u6e83\u75a1<\/span><\/section>\n<section style=\"margin-top: 0pt;margin-bottom: 0pt;text-align: justify;font-size: 10.5pt;font-family: \u7b49\u7ebf;font-weight: normal;margin-left: 21pt;line-height: 150%;text-indent: 0em;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 16px;\">\u6742\u5fd7\uff1aJournal of Ethnopharmacology<\/span><\/section>\n<section style=\"margin-top: 0pt;margin-bottom: 0pt;text-align: justify;font-size: 10.5pt;font-family: \u7b49\u7ebf;font-weight: normal;margin-left: 21pt;line-height: 150%;text-indent: 0em;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 16px;\">\u5f71\u54cd\u56e0\u5b50\uff1aIF=5.4<\/span><\/section>\n<section style=\"margin-top: 0pt;margin-bottom: 0pt;text-align: justify;font-size: 10.5pt;font-family: \u7b49\u7ebf;font-weight: normal;margin-left: 21pt;line-height: 150%;text-indent: 0em;\"><span style=\"font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 16px;\">\u53d1\u8868\u65f6\u95f4\uff1a2024\u5e741\u6708<\/span><\/section>\n<section style=\"line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-family:Times New Roman;mso-ascii-font-family:Times New Roman;mso-fareast-font-family:\u5b8b\u4f53;font-variant:normal;text-transform:none;\">          <o:p> <\/o:p><\/span><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 112, 192);font-weight: bold;font-size: 18px;\">\u7814\u7a76\u80cc\u666f<\/span><\/section>\n<section style=\"line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;mso-bidi-font-size:12.0pt;font-family:\u5b8b\u4f53;mso-ascii-font-family:Times New Roman;mso-bidi-font-family:\u5b8b\u4f53;font-variant:normal;text-transform:none;mso-font-kerning:0.0pt;\">\u7cd6\u5c3f\u75c5\u6e83\u75a1\uff08DU\uff09\u662f\u6162\u6027\u4f24\u53e3\uff0c\u5c5e\u4e8e\u7cd6\u5c3f\u75c5\u7684\u4e25\u91cd\u5e76\u53d1\u75c7\u3002\u8be5\u75c5\u5f71\u54cd\u4e86\u5927\u7ea630%\u7684\u7cd6\u5c3f\u75c5\u60a3\u8005\uff0c\u751a\u81f3\u53ef\u80fd\u5bfc\u81f4\u4e0b\u80a2\u622a\u80a2\u548c\u6b7b\u4ea1\u3002DU\u4e2d\u795e\u7ecf\u75c5\u53d8\u3001\u7f3a\u8840\u548c\u9ad8\u8840\u7cd6\u7684\u7ed3\u5408\u663e\u8457\u6291\u5236\u4e86\u8f6f\u7ec4\u7ec7\u4e2d\u4f24\u53e3\u548c\u6e83\u75a1\u7684\u6108\u5408\uff0c\u5bfc\u81f4\u4f24\u53e3\u4fee\u590d\u5ef6\u8fdf\u3002\u76ee\u524dDU\u7684\u6cbb\u7597\u65b9\u6cd5\u5728\u5176\u6709\u6548\u6027\u65b9\u9762\u5b58\u5728\u8bb8\u591a\u5c40\u9650\u6027\uff0c\u8feb\u5207\u9700\u8981\u5728\u5168\u79d1\u533b\u5b66\u4e2d\u91c7\u7528\u65b0\u9896\u6709\u6548\u7684\u6cbb\u7597\u65b9\u6cd5\u6765\u89e3\u51b3\u8fd9\u4e00\u7d27\u8feb\u95ee\u9898\u3002\u52a0\u5de5\u8fc7\u7684\u832f\u82d3\u5177\u6709\u4e00\u7cfb\u5217\u751f\u7269\u6d3b\u6027\uff0c\u5305\u62ec\u6297\u708e\u3001\u6297\u83cc\u548c\u6297\u6c27\u5316\u6d3b\u6027\u3002\u56e0\u6b64\uff0c\u6211\u4eec\u5047\u8bbe\u832f\u82d3\u5728\u6cbb\u7597DU\u65b9\u9762\u5177\u6709\u5de8\u5927\u7684\u6f5c\u529b\u3002<\/span><span style=\"color: rgb(255, 0, 0);font-family: "Times New Roman";font-size: 12pt;text-align: left;text-indent: 0em;letter-spacing: 0.034em;\">         <\/span><o:p style=\"color: rgb(255, 0, 0);font-family: "Times New Roman";font-size: 12pt;text-align: left;text-indent: 0em;letter-spacing: 0.034em;\"> <\/o:p><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 112, 192);font-weight: bold;font-size: 18px;\">\u6570\u636e\u6765\u6e90<\/span><\/section>\n<section style=\"text-align: left;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;font-family:\u5b8b\u4f53;mso-ascii-font-family:Times New Roman;mso-bidi-font-family:\u5b8b\u4f53;font-variant:normal;text-transform:none;\">\u57fa\u4e8eTCMSP\u3001HERB\u6570\u636e\u5e93\u548c\u76f8\u5173\u6587\u732e\uff0c\u6536\u96c6\u4e86\u832f\u82d3\u7684\u6240\u6709\u9776\u70b9\u3002DU\u7684\u9776\u6807\u662f\u4eceGeneCards\u548cNCBI\u57fa\u56e0\u6570\u636e\u5e93\u4e2d\u83b7\u5f97\u7684\u3002\u6b64\u5916\uff0c\u4f7f\u7528UniProt\u6570\u636e\u5e93\u5bf9\u76ee\u6807\u4fe1\u606f\u8fdb\u884c\u4e86\u8c03\u6574\u3002<\/span>    <o:page><\/o:page><\/section>\n<section style=\"margin-top: 7.8pt;margin-bottom: 7.8pt;text-align: center;line-height: 150%;text-indent: 0em;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 112, 192);font-weight: bold;font-size: 18px;\">\u7814\u7a76\u601d\u8def<\/span><\/section>\n<section style=\"line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;mso-bidi-font-size:14.0pt;font-family:\u5b8b\u4f53;mso-ascii-font-family:Times New Roman;font-variant:normal;text-transform:none;\">\u65e8\u5728\u5229\u7528UHPLC-Q-TOF-MS\u548cTCMSP\u6570\u636e\u5e93\u9274\u5b9a\u832f\u82d3\u7684\u6d3b\u6027\u5316\u5408\u7269\u548c\u6f5c\u5728\u9776\u70b9\uff0c\u786e\u5b9a\u4e0e\u7cd6\u5c3f\u75c5\u6e83\u75a1\u76f8\u5173\u7684\u9776\u70b9\u3002\u5bcc\u96c6\u5206\u6790\u540e\uff0c\u6784\u5efa\u86cb\u767d\u8d28-\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\u3001\u5206\u5b50\u5bf9\u63a5\u3002\u4f7f\u7528\u4eba\u8110\u9759\u8109\u8840\u7ba1\u5185\u76ae\u7ec6\u80de\u548c\u4eba\u9ad3\u7cfb\u767d\u8840\u75c5\u5355\u6838\u7ec6\u80de\uff08THP-1\uff09\u8fdb\u884c\u4e86\u4f53\u5916\u5b9e\u9a8c\u3002\u5728\u8fd9\u4e9b\u5b9e\u9a8c\u4e2d\u5e94\u7528\u4e86\u832f\u82d3\u7684\u6d3b\u6027\u6210\u5206\u3002\u7814\u7a76\u5305\u62ec\u5404\u79cd\u68c0\u6d4b\uff0c\u5982CCK-8\u3001\u5212\u75d5\u8bd5\u9a8c\u3001\u514d\u75ab\u8367\u5149\u3001\u86cb\u767d\u8d28\u5370\u8ff9\u3001RT-PCR\u548c\u6d41\u5f0f\u7ec6\u80de\u672f\uff0c\u4ee5\u63a2\u7d22\u832f\u82d3\u4e09\u841c\u63d0\u53d6\u7269\uff08PTE\uff09\u5728\u6cbb\u7597\u7cd6\u5c3f\u75c5\u6e83\u75a1\u65b9\u9762\u7684\u6f5c\u529b\u3002<\/span><\/section>\n<section style=\"line-height: 150%;text-indent: 0em;text-align: center;margin-bottom: 24px;\"><span style=\"font-family:\u7b49\u7ebf;mso-ascii-font-family:\u7b49\u7ebf;mso-fareast-font-family:\u7b49\u7ebf;font-variant:normal;text-transform:none;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100009492\" data-ratio=\"0.5296296296296297\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_hG7Qs2GHX3VQG7OhsHFibNuerrDH3g.jpg?resize=553%2C293\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/hud5kpqc1LT7ZGomgAumVjdf8p9sw4sXr6vzhYMsl0b4Gic4MO1SxibFEhfhG7Qs2GHX3VQG7OhsHFibNuerrDH3g\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"1080\" height=\"293 .5400390625\" width=\"553 .739990234375\" data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;mso-bidi-font-size:14.0pt;font-family:Times New Roman;mso-ascii-font-family:Times New Roman;mso-fareast-font-family:\u5b8b\u4f53;font-variant:normal;text-transform:none;color:#FF0000;\">          <o:p> <\/o:p><\/span><\/section>\n<section style=\"margin-top: 7.8pt;margin-bottom: 7.8pt;text-align: center;line-height: 150%;text-indent: 0em;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 112, 192);font-weight: bold;font-size: 18px;\">\u4e3b\u8981\u7ed3\u679c<\/span><\/section>\n<section style=\"margin-top: 7.8pt;margin-bottom: 7.8pt;text-align: left;line-height: 150%;text-indent: 0em;\"><span style=\"font-size:12.0pt;line-height:150%;mso-bidi-font-size:14.0pt;font-family:Times New Roman;mso-ascii-font-family:Times New Roman;mso-fareast-font-family:\u5b8b\u4f53;font-variant:normal;text-transform:none;font-weight:bold;mso-bidi-font-weight:bold;\">1. \u832f\u82d3\u4e2d\u6210\u5206\u7684\u9274\u5b9a<\/span><\/section>\n<section style=\"line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;mso-bidi-font-size:14.0pt;font-family:\u5b8b\u4f53;mso-ascii-font-family:Times New Roman;font-variant:normal;text-transform:none;\">\u5bf9\u832f\u82d3\u8fdb\u884c\u4e86\u5b9a\u6027\u5206\u6790\uff0c\u901a\u8fc7UHPLC-Q-TOF-MS\/MS\u9274\u5b9a\u4e8656\u79cd\u6210\u5206\u3002PTE\u6210\u4e3a\u832f\u82d3\u7684\u4e3b\u8981\u6210\u5206\uff0cPTE\u7684\u603b\u79bb\u5b50\u8272\u8c31\u56fe\u5982\u56fe\u6240\u793a\uff08\u56fe1\uff09\u3002<\/span>    <o:page><\/o:page><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-family:\u7b49\u7ebf;mso-ascii-font-family:\u7b49\u7ebf;mso-fareast-font-family:\u7b49\u7ebf;font-variant:normal;text-transform:none;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100009491\" data-ratio=\"0.5876577840112202\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_uG7XmK0JLUxC2ibqHglib5VI2t15Kw.jpg?resize=403%2C237\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/hud5kpqc1LT7ZGomgAumVjdf8p9sw4sX19dCB6r5eLO3Bc2ZjURoMIZ0MQuG7XmK0JLUxC2ibqHglib5VI2t15Kw\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"713\" height=\"237 .33999633789062\" width=\"403 .71002197265625\" data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 14px;\">\u56fe1 \u8d1f\u79bb\u5b50\u6a21\u5f0f\u4e0b\u7684\u603b\u79bb\u5b50\u8272\u8c31\u56fe<\/span><\/section>\n<section style=\"margin-top: 7.8pt;margin-bottom: 7.8pt;text-align: left;line-height: 150%;text-indent: 0em;\"><span style=\"font-size: 12pt;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: bold;\">2. \u7f51\u7edc\u836f\u7406\u5b66\u663e\u793a\u832f\u82d3\u7684\u4e09\u841c\u7c7b\u5316\u5408\u7269\u4f9d\u9760PI3K-AKT\u4fe1\u53f7\u901a\u8def\u6765\u7f13\u89e3DU<\/span><\/section>\n<section style=\"text-align: left;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;mso-bidi-font-size:14.0pt;font-family:\u5b8b\u4f53;mso-ascii-font-family:Times New Roman;font-variant:normal;text-transform:none;\">\u672c\u7814\u7a76\u7684\u7f51\u7edc\u836f\u7406\u5b66\u90e8\u5206\uff0c\u786e\u5b9a\u4e86\u832f\u82d3\u4e2d74\u4e2a\u6f5c\u5728\u9776\u70b9\u548c12\u79cd\u6d3b\u6027\u6210\u5206\uff0c\u8fd9\u4e9b\u9776\u70b9\u53ef\u4ee5\u7f13\u89e3DUs\uff08\u56fe2A\uff09\u3002PPI \u7f51\u7edc\u4e2d\uff08\u56fe2B\uff09\uff0c\u7ebf\u6761\u7684\u7c97\u7ec6\u4ee3\u8868\u4e86\u4e2d\u95f4\u4e2d\u5fc3\u6027\u3002PPI\u7f51\u7edc\u7684\u67a2\u7ebd\u8282\u70b9\u7b5b\u9009\uff08\u56fe2C\uff09\u786e\u5b9a\u4e86JUN\u3001STAT3\u3001MAPK1\u3001AKT1\u548cCTNNB\u662f\u832f\u82d3\u6cbb\u7597\u7cd6\u5c3f\u75c5\u6e83\u75a1\uff08DUs\uff09\u6d3b\u6027\u6210\u5206\u7684\u6838\u5fc3\u9776\u70b9\u3002\u56fe2D-E\u663e\u793a<\/span><span style=\"font-size:12.0pt;line-height:150%;mso-bidi-font-size:14.0pt;font-family:\u5b8b\u4f53;mso-ascii-font-family:Times New Roman;font-variant:normal;text-transform:none;\">\u4e86GO\u5bcc\u96c6\u5206\u6790\u548cKEGG\u5bcc\u96c6\u5206\u6790\u7ed3\u679c\uff08P < 0.05\uff09\uff0c\u65e8\u5728\u63a2\u7a76\u832f\u82d3\u6539\u5584DU\u7684\u6f5c\u5728\u673a\u5236\u3002\u5f3a\u8c03\u4e86PI3K-AKT\u901a\u8def\u5728\u832f\u82d3\u7f13\u89e3\u7cd6\u5c3f\u75c5\u5e76\u53d1\u75c7DU\u4e2d\u7684\u6f5c\u5728\u610f\u4e49\uff08\u56fe2F\uff09\u3002\u5316\u5408\u7269-\u9776\u70b9\u548c\u9776\u70b9-\u901a\u8def\u7f51\u7edc\u5206\u6790\u663e\u793a\u4e86\u4e0e\u5316\u5408\u7269\u3001\u9776\u70b9\u548c\u901a\u8def\u7684\u5173\u7cfb\uff08\u56fe2G-H\uff09\u3002   <\/span><o:page><\/o:page><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-family:\u7b49\u7ebf;mso-ascii-font-family:\u7b49\u7ebf;mso-fareast-font-family:\u7b49\u7ebf;font-variant:normal;text-transform:none;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100009495\" data-ratio=\"1.436931079323797\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_T6CroYpPj4sOlx7beicYhYzVfKGrkw.jpg?resize=335%2C481\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/hud5kpqc1LT7ZGomgAumVjdf8p9sw4sXdiczUwMDffns44vjePPHRTkxRfT6CroYpPj4sOlx7beicYhYzVfKGrkw\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"769\" height=\"481 .3699951171875\" width=\"335 .34002685546875\" data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 14px;\">\u56fe2 \u7f51\u7edc\u836f\u7406\u5b66\u7814\u7a76\u832f\u82d3\u6297DU\u7684\u4f5c\u7528\u673a\u5236<\/span><\/section>\n<section style=\"text-align: left;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;font-family:Times New Roman;mso-ascii-font-family:Times New Roman;mso-fareast-font-family:\u5b8b\u4f53;mso-bidi-font-family:\u5b8b\u4f53;font-variant:normal;text-transform:none;font-weight:bold;mso-bidi-font-weight:bold;\">3. \u5173\u952e\u4e09\u841c\u7c7b\u5316\u5408\u7269\u4e0eP13K\u86cb\u767d\u8868\u73b0\u51fa\u663e\u8457\u7684\u7ed3\u5408\u6d3b\u6027<\/span><\/section>\n<section style=\"text-align: left;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;mso-bidi-font-size:14.0pt;font-family:\u5b8b\u4f53;mso-ascii-font-family:Times New Roman;font-variant:normal;text-transform:none;\">\u65e2\u5f80\u7814\u7a76\u8868\u660e\uff0cPTE\u6539\u5584\u9ad8\u7cd6\u8bf1\u5bfc\u7684HUVEC\u529f\u80fd\u969c\u788d\u7684\u6cbb\u7597\u673a\u5236\u4e0eP13K\u86cb\u767d\u7684\u8868\u8fbe\u5bc6\u5207\u76f8\u5173\u3002\u5229\u7528UHPLC-Q-TOF-MS\uff0c\u9274\u5b9a\u4e86\u832f\u82d3\u7684\u51e0\u79cd\u4e09\u841c\u7c7b\u6210\u5206\uff0c\u5305\u62ec16\u03b1-\u7f9f\u57fa\u8131\u6c22\u66f2\u7f8e\u70ef\u9187\u9178\u3001\u8131\u6c22\u82a6\u82d3\u9178\u3001\u832f\u82d3\u9178A\u3001\u8331\u82d3\u9178B\u3001\u8331\u82d3\u9178C\u548c\u539a\u9178\u3002\u4f7f\u7528\u5206\u5b50\u5bf9\u63a5\u9a8c\u8bc1\u4e86\u6d3b\u6027\u6210\u5206\u4e0ePI3K\u7684\u7ed3\u5408\u4eb2\u548c\u529b\u3002\u9664\u591a\u8334\u9999\u9178c\u5916\uff0c\u6240\u6709\u6765\u81ea\u832f\u82d3\u7684\u4e09\u841c\u7c7b\u5316\u5408\u7269\u5747\u4e0ePI3K\u86cb\u767d\u8868\u73b0\u51fa\u663e\u8457\u7684\u7ed3\u5408\u6d3b\u6027\u3002\u8fd9\u4e9b\u53d1\u73b0\u8868\u660e\uff0c\u8fd9\u4e9b\u4e09\u841c\u7c7b\u5316\u5408\u7269\u53ef\u80fd\u662f\u7f13\u89e3\u7cd6\u5c3f\u75c5\u6e83\u75a1\uff08DUs\uff09\u7684\u5173\u952e\u6210\u5206\uff08\u56fe3\uff09\u3002<\/span>    <o:page><\/o:page><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-family:\u7b49\u7ebf;mso-ascii-font-family:\u7b49\u7ebf;mso-fareast-font-family:\u7b49\u7ebf;font-variant:normal;text-transform:none;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100009498\" data-ratio=\"0.47129629629629627\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_iamrXjzpRdXOOUpgaWlQPQLNyxy93Q.jpg?resize=553%2C261\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/hud5kpqc1LT7ZGomgAumVjdf8p9sw4sXKg9pkrSuhXS2oA6b67Qh5WvaIiamrXjzpRdXOOUpgaWlQPQLNyxy93Q\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"1080\" height=\"261 .2699890136719\" width=\"553 .739990234375\" data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 14px;\">\u56fe2 \u832f\u82d3\u4e0eP13K\u86cb\u767d\u7ed3\u5408\u7684\u5206\u5b50\u5bf9\u63a5\u9a8c\u8bc1<\/span><\/section>\n<section style=\"text-align: left;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;mso-bidi-font-size:14.0pt;font-family:Times New Roman;mso-ascii-font-family:Times New Roman;mso-fareast-font-family:\u5b8b\u4f53;font-variant:normal;text-transform:none;font-weight:bold;mso-bidi-font-weight:bold;\">4. PTE\u6539\u5584\u9ad8\u7cd6\u8bf1\u5bfc\u7684 HUVEC \u529f\u80fd\u969c\u788d<\/span><\/section>\n<section style=\"text-align: left;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;mso-bidi-font-size:14.0pt;font-family:\u5b8b\u4f53;mso-ascii-font-family:Times New Roman;font-variant:normal;text-transform:none;\">\u7ed3\u5408\u7f51\u7edc\u836f\u7406\u5b66\u7814\u7a76\uff0c\u5c06PTE\u786e\u5b9a\u4e3a\u832f\u82d3\u7684\u4e3b\u8981\u6210\u5206\u3002\u5f00\u59cb\u8bc4\u4f30PTE\u5728\u4f53\u5916\u6cbb\u7597\u7cd6\u5c3f\u75c5\u6e83\u75a1\u7684\u7597\u6548\u3002\u4f7f\u7528CCK-8\u6d4b\u5b9a\u6cd5\uff0c\u68c0\u67e5\u4e86\u5728\u4e0d\u540c\u6d53\u5ea6\u7684PTE\u4e0b HUVEC\u7684\u589e\u6b96\uff08\u56fe3A\uff09\u3002\u572810 mg\/L\u6d53\u5ea6\u4e0b\uff0cPTE\u4e0d\u5f71\u54cd\u7ec6\u80de\u7684\u589e\u6b96\u6d3b\u6027\u3002\u5f53PTE\u6d53\u5ea6\u8d85\u8fc750 mg\/L\u65f6\uff0c\u7ec6\u80de\u6d3b\u6027\u4e0b\u964d\u3002\u9009\u62e9\u4e8610 mg\/L\u7684PTE\u6d53\u5ea6\u8fdb\u884c\u8fdb\u4e00\u6b65\u7684\u5e72\u9884\u5b9e\u9a8c\u3002\u63a5\u4e0b\u6765\uff0c\u8fdb\u884c\u7ec6\u80de\u5212\u75d5\u5b9e\u9a8c\uff0c\u7ed3\u679c\u5982\u56fe3B-C\u6240\u793a\u3002\u4e0e\u5bf9\u7167\u7ec4\u76f8\u6bd4\uff0cHG\u7ec424 h\u8fc1\u79fb\u7387\u663e\u8457\u964d\u4f4e\u3002\u901a\u8fc7RT-PCR\u5206\u6790CD31\u548cVEGF\u7684mRNA\u8868\u8fbe\uff08\u56fe3D\uff09\u3002\u7ec6\u80de\u514d\u75ab\u8367\u5149\u7528\u4e8e\u68c0\u6d4bVEGF\u7684\u8868\u8fbe\uff08\u56fe3E\uff09\u3002\u8fd9\u4e9b\u7ed3\u679c\u8868\u660e\uff0c\u9ad8\u8461\u8404\u7cd6\uff08HG\uff09\u6291\u5236HUVECs\u7684\u8840\u7ba1\u751f\u6210\uff0c\u4f7f\u7528PTE\u53ef\u4ee5\u6709\u6548\u6539\u5584\u8fd9\u79cd\u6291\u5236\u4f5c\u7528\u3002<\/span>    <o:page><\/o:page><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-family:\u7b49\u7ebf;mso-ascii-font-family:\u7b49\u7ebf;mso-fareast-font-family:\u7b49\u7ebf;font-variant:normal;text-transform:none;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100009499\" data-ratio=\"1.4329896907216495\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_dMibvt7S12SGYLp2d88Slt5RRtEqUQ.jpg?resize=380%2C545\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/hud5kpqc1LT7ZGomgAumVjdf8p9sw4sXQETFcNxCYud9ZvoGANvIEZlC8dMibvt7S12SGYLp2d88Slt5RRtEqUQ\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"873\" height=\"545 .2100219726562\" width=\"380 .6700439453125\" data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 14px;\">\u56fe3 PTE\u53ef\u4ee5\u6539\u5584\u9ad8\u7cd6\u8bf1\u5bfc\u7684HUVECs\u7ec6\u80de\u529f\u80fd\u969c\u788d<\/span><\/section>\n<section style=\"text-align: left;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-family: "Times New Roman";font-size: 12pt;font-weight: bold;text-align: left;text-indent: 0em;letter-spacing: 0.034em;\">5. PTE\u901a\u8fc7\u8c03\u8282 PI3K-AKT \u4fe1\u53f7\u4f20\u5bfc\u6539\u5584\u9ad8\u7cd6\u8bf1\u5bfc\u7684HUVEC\u529f\u80fd\u969c\u788d<\/span><\/section>\n<section style=\"text-align: left;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;mso-bidi-font-size:14.0pt;font-family:\u5b8b\u4f53;mso-ascii-font-family:Times New Roman;font-variant:normal;text-transform:none;\">LY294002 \u548cp-PI3K\u6291\u5236\u5242\u7528\u4e8e\u76f4\u63a5\u68c0\u67e5PTE\u5bf9PI3K-AKT\u4fe1\u53f7\u901a\u8def\u7684\u5f71\u54cd\uff08\u56fe4A-B\uff09\u3002\u7ed3\u679c\u8868\u660e\uff0cPTE\u4fc3\u8fdbPI3K-AKT\u901a\u8def\u4fe1\u53f7\u8f6c\u5bfc\uff0c\u5e76\u5728\u4fc3\u8fdb\u8840\u7ba1\u751f\u6210\u65b9\u9762\u53d1\u6325\u6cbb\u7597\u4f5c\u7528\u3002<\/span>    <o:page><\/o:page><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-family:\u7b49\u7ebf;mso-ascii-font-family:\u7b49\u7ebf;mso-fareast-font-family:\u7b49\u7ebf;font-variant:normal;text-transform:none;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100009497\" data-ratio=\"0.6581196581196581\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/10_fxZoZY2kHxmN6sfN1rgwxQME4shReQ.jpg?resize=408%2C268\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/hud5kpqc1LT7ZGomgAumVjdf8p9sw4sXHRVk96TibG1mLbl1whK5g9tqmfxZoZY2kHxmN6sfN1rgwxQME4shReQ\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"936\" height=\"268 .6499938964844\" width=\"408 .010009765625\" data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 14px;\">\u56fe4 PTE\u901a\u8fc7\u8c03\u8282PI3K-AKT\u4fe1\u53f7\u901a\u8def\u6539\u5584\u9ad8\u7cd6\u8bf1\u5bfc\u7684HUVECs\u7ec6\u80de\u529f\u80fd\u969c\u788d<\/span><\/section>\n<section style=\"text-align: left;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;mso-bidi-font-size:14.0pt;font-family:Times New Roman;mso-ascii-font-family:Times New Roman;mso-fareast-font-family:\u5b8b\u4f53;font-variant:normal;text-transform:none;font-weight:bold;mso-bidi-font-weight:bold;\">5. PTE\u6539\u5584LPS\u8bf1\u5bfc\u7684THP-1\u7ec6\u80de\u708e\u75c7\u53cd\u5e94<\/span><\/section>\n<section style=\"text-align: left;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;mso-bidi-font-size:14.0pt;font-family:\u5b8b\u4f53;mso-ascii-font-family:Times New Roman;font-variant:normal;text-transform:none;\">M1\u5de8\u566c\u7ec6\u80de\u7684\u6781\u5316\u5728\u7ef4\u6301\u708e\u75c7\u53cd\u5e94\u4e2d\u8d77\u7740\u91cd\u8981\u4f5c\u7528\u3002\u4e3a\u4e86\u8bc4\u4f30PTE\u5728\u6539\u5584\u7ec6\u80de\u708e\u75c7\u53cd\u5e94\u65b9\u9762\u7684\u6f5c\u529b\uff0c\u7814\u7a76\u4e86\u5176\u5bf9THP-1\u5de8\u566c\u7ec6\u80de\u7684\u5f71\u54cd\u3002PTE \u5e72\u9884\u5bfc\u81f4\u708e\u75c7\u56e0\u5b50TNF-\u03b1\u3001IL-1\u03b2\u3001IL-6\u548cNF-\u03baB\u7684mRNA\u8868\u8fbe\u964d\u4f4e\u3002PTE\u901a\u8fc7\u6781\u5316M2 \u5de8\u566c\u7ec6\u80de\u548c\u51cf\u5c11\u4fc3\u708e\u56e0\u5b50\u7684\u5206\u6ccc\u6765\u53d1\u6325\u6297\u708e\u4f5c\u7528\uff08\u56fe5\uff09\u3002<\/span><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-family:\u7b49\u7ebf;mso-ascii-font-family:\u7b49\u7ebf;mso-fareast-font-family:\u7b49\u7ebf;font-variant:normal;text-transform:none;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100009496\" data-ratio=\"0.71875\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/11_RvELbY9PkH7qgXO0dWe6jfYt8FPicA.jpg?resize=376%2C270\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/hud5kpqc1LT7ZGomgAumVjdf8p9sw4sXZSLmgs3qASrJEuCs63ibJVG0qxRvELbY9PkH7qgXO0dWe6jfYt8FPicA\/640?wx_fmt=jpeg'\" data-type=\"jpeg\" data-w=\"864\" height=\"270 .44000244140625\" width=\"376 .0099792480469\" data-recalc-dims=\"1\" \/><\/span><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-size: 14px;\">\u56fe5 PTE\u901a\u8fc7\u8c03\u8282PI3K-AKT\u4fe1\u53f7\u901a\u8def\u6539\u5584\u9ad8\u7cd6\u8bf1\u5bfc\u7684HUVECs\u7ec6\u80de\u529f\u80fd\u969c\u788d<\/span><\/section>\n<section style=\"text-align: center;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><o:page><\/o:page><\/section>\n<section style=\"margin-top: 7.8pt;margin-bottom: 7.8pt;text-align: center;line-height: 150%;text-indent: 0em;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 112, 192);font-weight: bold;font-size: 18px;\">\u6587\u7ae0\u5c0f\u7ed3<\/span><\/section>\n<section style=\"margin-top: 7.8pt;line-height: 150%;text-indent: 0em;margin-bottom: 24px;\"><span style=\"font-size:12.0pt;line-height:150%;mso-bidi-font-size:14.0pt;font-family:\u5b8b\u4f53;mso-ascii-font-family:Times New Roman;font-variant:normal;text-transform:none;\">\u8fd9\u662f\u9996\u6b21\u9610\u660e\u4ece\u832f\u82d3\u4e2d\u63d0\u53d6\u7684\u5404\u79cd\u751f\u7269\u6d3b\u6027\u4e09\u841c\u7c7b\u5316\u5408\u7269\u6210\u5206\u7528\u4e8e\u6cbb\u7597\u7cd6\u5c3f\u75c5\u6e83\u75a1\u7684\u6f5c\u529b\u3002\u6b64\u5916\uff0c\u8fd9\u9879\u7814\u7a76\u8868\u660e\uff0cPTE\u901a\u8fc7\u8c03\u8282PI3K-AKT\u4fe1\u53f7\u4f20\u5bfc\uff0c\u7279\u522b\u662f\u901a\u8fc7\u6fc0\u6d3bp-AKT\u548cp-PI3K\u86cb\u767d\uff0c\u7f13\u89e3\u4e86\u9ad8\u8840\u7cd6\u6c34\u5e73\u8bf1\u5bfc\u7684HUVEC\u529f\u80fd\u969c\u788d\u3002\u4e2d\u533b\u836f\u7684\u5c0f\u4f19\u4f34\u53ef\u522b\u9519\u8fc7\uff01\u5145\u5206\u5229\u7528\u7f51\u7edc\u836f\u7406\u5b66\u52a9\u653b\u4e2d\u533b\u836f\u5b9e\u9a8c\u7814\u7a76\uff0c\u60f3\u590d\u73b0\u601d\u8def\u7684\u670b\u53cb\u5feb\u5feb\u8054\u7cfb\u5c0f\u9014\u5427\uff01\u4f4e\u6210\u672c\u3001\u5468\u671f\u77ed\u76845\u5206\u4f5c\u4e1a\u5feb\u6284\u8d77\u6765\uff01<\/span><span style=\"font-family: "Times New Roman";font-size: 12pt;text-indent: 0em;letter-spacing: 0.034em;\">         <\/span><o:p style=\"font-family: "Times New Roman";font-size: 12pt;text-indent: 0em;letter-spacing: 0.034em;\"> <\/o:p><\/section>\n<p style=\"text-indent: 0px;margin-bottom: 0px;\"><span style=\"color: rgb(0, 122, 170);\"><strong><span style=\"color: rgb(0, 122, 170);letter-spacing: 0.578px;text-indent: 32px;text-wrap: wrap;background-color: rgb(255, 255, 255);font-size: 15px;\">\u5c0f\u679c\u8fd8<span style=\"color: rgb(0, 122, 170);background-color: rgb(255, 255, 255);font-size: 15px;letter-spacing: 0.578px;text-decoration: none solid rgba(0, 0, 0, 0.9);\">\u63d0\u4f9b\u601d\u8def\u8bbe\u8ba1\u3001\u5b9a\u5236\u751f\u4fe1\u5206\u6790\u3001\u6587\u732e\u601d\u8def\u590d\u73b0\uff1b\u6709\u9700\u8981\u7684\u5c0f\u4f19\u4f34\u6b22\u8fce\u76f4\u63a5\u626b\u7801\u54a8\u8be2\u5c0f\u679c\uff0c\u7aed\u8bda\u4e3a\u60a8\u7684\u79d1\u7814\u52a9\u529b\uff01<\/span><\/span><\/strong><\/span><\/p>\n<p style=\"margin-bottom: 0px;\"><br \/><\/p>\n<section style=\"font-size: 15px;padding-right: 2px;padding-left: 2px;margin-bottom: 0px;\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;flex: 0 0 auto;height: auto;border-color: rgb(114, 114, 114);border-width: 1px;border-style: solid;box-shadow: rgb(194, 209, 255) -5px 5px 0px;align-self: flex-start;\">\n<section style=\"justify-content: center;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 42.6829%;vertical-align: middle;box-shadow: rgb(43, 65, 110) 0px 0px 0px;flex: 0 0 auto;height: auto;padding-left: 10px;align-self: center;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;line-height: 0;transform: translate3d(20px, 0px, 0px);\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;width: 75%;height: auto;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-imgfileid=\"100017023\" data-ratio=\"1\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_B2jkicacLzPjw4xMSqVvoucZjonVDA-21.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAxVYfSsM0wdf9d3RpNiaTcHohxPNEVs2VFhPMukpU8lchxrvcB2jkicacLzPjw4xMSqVvoucZjonVDA\/640?wx_fmt=jpeg'&from=appmsg\" data-type=\"jpeg\" data-w=\"430\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: 56.9106%;flex: 0 0 auto;height: auto;align-self: center;\">\n<section style=\"line-height: 2;letter-spacing: 1px;color: rgb(43, 65, 110);\" powered-by=\"xiumi.us\">\n<p style=\"margin-bottom: 2px;\"><strong>\u5b9a\u5236\u751f\u4fe1\u5206\u6790<\/strong><\/p>\n<p style=\"margin-bottom: 2px;\"><strong>\u670d\u52a1\u5668\u79df\u8d41<\/strong><\/p>\n<p><strong>\u626b\u7801\u54a8\u8be2\u5c0f\u679c<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p powered-by=\"xiumi.us\"><br \/><\/p>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247497780&idx=2&sn=7eee90af6f387e4153bba13028e545a1&chksm=cf7f68f1f808e1e7dfb3a0597ef442e5c6e700ecf6ee5a035c766a4c7486c12eabd0ab218ea6&scene=21#wechat_redirect\" textvalue=\"\u4f60\u5df2\u9009\u4e2d\u4e86\u6dfb\u52a0\u94fe\u63a5\u7684\u5185\u5bb9\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"1\" rel=\"noopener\"><span class=\"js_jump_icon h5_image_link\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-imgfileid=\"100017024\" data-ratio=\"0.3253333333333333\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/13_7TvAyUibd1TPhJmZfialJtv6tu2SEg-33.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAxVYfSsM0wdf9d3RpNiaTcHoj9xlsoyiaBvzaezDUFAicibMAF8ts7TvAyUibd1TPhJmZfialJtv6tu2SEg\/640?wx_fmt=png&from=appmsg'\" data-type=\"png\" data-w=\"750\" style=\"vertical-align: middle;width: 100%;\" data-recalc-dims=\"1\" \/><\/span><\/a><\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img decoding=\"async\" class=\"rich_pages wxw-img js_insertlocalimg\" data-imgfileid=\"100017025\" data-ratio=\"0.3811111111111111\" data-s=\"300,640\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/14_9N02aBaau07RufXeXRLmvAHsrFZxtw-31.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAz5wg6Ne6sYkannSE9NiatkcPh3icbKanJagacjU6LqJrGAL29N02aBaau07RufXeXRLmvAHsrFZxtw\/640?wx_fmt=jpeg&from=appmsg'\" data-type=\"jpeg\" data-w=\"900\" style=\"letter-spacing: 0.578px;text-align: center;text-wrap: wrap;\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;text-align: left;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-end;padding-right: 2px;padding-left: 2px;\">\n<section style=\"margin: 10px 0% 2px;transform: translate3d(2px, 0px, 0px);\" powered-by=\"xiumi.us\">\n<section style=\"font-size: 16px;color: rgb(58, 66, 94);line-height: 1;letter-spacing: 5px;text-align: center;\">\n<p><strong>\u5f80\u671f\u56de\u987e<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"height: 3px;background-color: rgb(95, 156, 239);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<section style=\"margin-top: 2px;margin-right: 0%;margin-left: 0%;text-align: center;line-height: 0.8;font-size: 9px;\" powered-by=\"xiumi.us\">\n<section style=\"width: 0px;display: inline-block;border-top: 0.8em solid rgb(58, 66, 94);border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;flex: 100 100 0%;align-self: flex-end;height: auto;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"height: 3px;background-color: rgb(95, 156, 239);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<section style=\"margin-top: 2px;margin-right: 0%;margin-left: 0%;text-align: center;line-height: 0.8;font-size: 9px;\" powered-by=\"xiumi.us\">\n<section style=\"width: 0px;display: inline-block;border-top: 0.8em solid rgba(255, 255, 255, 0);border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"min-height: 40px;margin: 10px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"width: 100%;margin-right: auto;margin-bottom: -10px;margin-left: auto;\">\n<table width=\"100%\">\n<tbody>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:0\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:0.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>01<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247497780&idx=2&sn=7eee90af6f387e4153bba13028e545a1&chksm=cf7f68f1f808e1e7dfb3a0597ef442e5c6e700ecf6ee5a035c766a4c7486c12eabd0ab218ea6&scene=21#wechat_redirect\" textvalue=\"1024G\u5b58\u50a8\u7684\u751f\u4fe1\u670d\u52a1\u5668\uff0c\u4e24\u4eba\u6210\u56e2\uff0c1\u4eba\u514d\u5355\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">1024G\u5b58\u50a8\u7684\u751f\u4fe1\u670d\u52a1\u5668\uff0c\u4e24\u4eba\u6210\u56e2\uff0c1\u4eba\u514d\u5355\uff01<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:1\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:1.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>02<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247498878&idx=1&sn=fc34ed3f1d15d060bbaf8166adcebd58&chksm=cf7f6cbbf808e5ad0b5417e50ed75cfbd1b3a83ac43b97f1dfa718c822878a9a004990075133&scene=21#wechat_redirect\" textvalue=\"\u5355\u4e2a\u6570\u636e\u5e93\u7528\u817b\u4e86\uff1f\u591a\u6570\u636e\u5e93\u201c\u7ec4\u5408\u62f3\u201d\u5e26\u4f60\u6253\u5f00\u514d\u75ab\u6d78\u6da6\u65b0\u601d\u8def\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u5355\u4e2a\u6570\u636e\u5e93\u7528\u817b\u4e86\uff1f\u591a\u6570\u636e\u5e93\u201c\u7ec4\u5408\u62f3\u201d\u5e26\u4f60\u6253\u5f00\u514d\u75ab\u6d78\u6da6\u65b0\u601d\u8def\uff01<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:2\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:2.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>03<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247498673&idx=1&sn=1e09b74a836c1e64a62ae1f66eeb3f93&chksm=cf7f6b74f808e262de70be43fd73bf5fefdc0914e525eb2032f741a0152e619689cedc76946f&scene=21#wechat_redirect\" textvalue=\"\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u7684\u51c6\u5907\u5de5\u4f5c\uff0cGWAS\u6570\u636e\u7684\u7f51\u7ad9\u4e0b\u8f7d\u65b9\u6cd5\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"11\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u7684\u51c6\u5907\u5de5\u4f5c\uff0cGWAS\u6570\u636e\u7684\u7f51\u7ad9\u4e0b\u8f7d\u65b9\u6cd5<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:3\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:3.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>04<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247498517&idx=1&sn=fa3c0104cee316982fe8162b79fe234f&chksm=cf7f6bd0f808e2c6cf979704bf883cfb5480444604f90da61dc286e7541fa5bb49df0a2fb58a&scene=21#wechat_redirect\" textvalue=\"\u8ddf\u7740\u5c0f\u679c\u5b66\u590d\u73b0-\u624b\u628a\u624b\u5e26\u4f60\u62ff\u4e0bIF=46.9Nature \u7ea7\u522b\u7684\u4e3b\u6210\u5206\u5206\u6790\uff08PCA\uff09\u56fe\uff01\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u8ddf\u7740\u5c0f\u679c\u5b66\u590d\u73b0-\u624b\u628a\u624b\u5e26\u4f60\u62ff\u4e0bIF=46.9Nature \u7ea7\u522b\u7684\u4e3b\u6210\u5206\u5206\u6790\uff08PCA\uff09\u56fe\uff01\uff01<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;margin-bottom: 0px;\"><span style=\"letter-spacing: 0.034em;text-align: justify;background-color: rgb(255, 255, 255);font-size: 16px;\"><\/span><br \/><\/p>\n<p style=\"display: none;margin-bottom: 24px;\"><mp-style-type data-value=\"3\"><\/mp-style-type><\/p>\n<p><\/content>\n<\/div>\n<p><\/body><br \/>\n<\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4e2d\u533b\u836f+\u7f51\u7edc\u836f\u7406\u5b66=\u6027\u4ef7\u6bd4\u4e4b\u738b\uff01\u540c\u6d4e\u5927\u5b66+\u5357\u4eac\u4e2d\u533b\u836f\u5927\u5b66\u5f3a\u5f3a\u8054\u5408\u53d1\u8868\u65b0\u4f5c\uff01\u7ecf\u5178\u901a\u8def+\u5e72\u6e7f\u7ed3\u5408\u5b9e\u73b0\u8f7b\u677e\u53d1\u6587\uff01 \u5c0f […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/59976"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=59976"}],"version-history":[{"count":1,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/59976\/revisions"}],"predecessor-version":[{"id":59991,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/59976\/revisions\/59991"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=59976"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=59976"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=59976"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}