{"id":60486,"date":"2024-06-17T11:28:09","date_gmt":"2024-06-17T03:28:09","guid":{"rendered":"http:\/\/www.biocloudservice.com\/wordpress\/?p=60486"},"modified":"2024-06-17T11:28:09","modified_gmt":"2024-06-17T03:28:09","slug":"%e7%81%ab%e8%bf%87%e5%bc%a0%e5%85%83%e8%8b%b1%e6%91%86%e8%83%af%ef%bc%9f%e8%bf%99%e5%a5%97%e5%8d%95%e7%bb%86%e8%83%9e%e5%88%86%e7%b1%bb%e6%b3%95%e5%ae%9e%e5%8a%9b%e5%bc%ba%e5%8a%b2%ef%bc%81%e6%b8%af","status":"publish","type":"post","link":"http:\/\/www.biocloudservice.com\/wordpress\/?p=60486","title":{"rendered":"\u706b\u8fc7\u5f20\u5143\u82f1\u6446\u80ef\uff1f\u8fd9\u5957\u5355\u7ec6\u80de\u5206\u7c7b\u6cd5\u5b9e\u529b\u5f3a\u52b2\uff01\u6e2f\u4e2d\u6587\u674e\u715c\u56e2\u961f9.5\u5206\uff1a\u6df1\u5ea6\u5b66\u4e60+\u81ea\u52a8\u6ce8\u91ca+\u65b0\u578b\u7ec6\u80de\u68c0\u6d4b\uff0c\u7b80\u5355\u65b9\u6cd5\u5e26\u6765\u66f4\u5f3a\u5927\u7684\u6027\u80fd\uff01"},"content":{"rendered":"


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none;\">\u672c\u6587\u5728\u4e0d\u540c\u65b0\u578b\u7a00\u6709\u7ec6\u80de\u7c7b\u578b\u548c\u4e0d\u540c\u79cd\u7fa4\u6a21\u5f0f\u4e0b\uff0c\u591a\u89d2\u5ea6\u9a8c\u8bc1\u4e86<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: normal;\">scNovel<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: normal;\">\u6a21\u578b\u80fd\u591f\u6709\u6548\u53d1\u73b0\u65b0\u578b\u7f55\u89c1\u7ec6\u80de<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u3002<\/span><\/span><\/p>\n<p style=\"margin-left: 0pt;text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\">4\uff0c<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u672c\u6587\u5f3a\u8c03\u4e86\u6a21\u578b\u53ef\u4ee5<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u5feb\u901f\u5bf9\u7ec6\u80de\u7c7b\u578b\u8fdb\u884c\u5206\u7c7b<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\uff0c\u5e76\u63ed\u793a\u8be5\u65b9\u6cd5\u5177\u6709<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u8f83\u597d\u7684\u53ef\u6269\u5c55\u6027<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u3002\u60f3\u8981\u53d1\u8868\u9ad8\u5206SCI\u7684\u5c0f\u4f19\u4f34\u4eec\u4e5f\u53ef\u4ee5\u501f\u9274\u4e00\u4e0b\u672c\u6587\u7684\u7814\u7a76\u601d\u8def\u54e6~ <\/span><span style=\"font-size: 16px;font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(255, 0, 0);font-weight: bold;\">(ps\uff1a\u5982\u4f55\u8f6c\u53d8\u601d\u8def\u5c06\u7b97\u6cd5\u5e94\u7528\u5230<\/span><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(255, 0, 0);font-weight: bold;\">\u4e34\u5e8a\u533b\u5b66\u76f8\u5173\u9886\u57df\u5462\uff1f\u8ba9\u5c0f\u9014\u5f15\u9886\u4f60\u63a2\u7d22\u751f\u7269\u533b\u836f\u7814\u7a76\u7684\u65b0\u9886\u57df\uff0c\u6709\u5174\u8da3\u7684\u8bdd\u5feb\u626b\u7801\u4ea4\u6d41\u5427\uff01\uff01)\u3002<\/span>   <\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-imgfileid=\"100017759\" data-ratio=\"1\" data-s=\"300,640\" data-type=\"jpeg\" data-w=\"430\" style=\"width: 190px;height: auto !important;\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_B2jkicacLzPjw4xMSqVvoucZjonVDA-62.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAxVYfSsM0wdf9d3RpNiaTcHohxPNEVs2VFhPMukpU8lchxrvcB2jkicacLzPjw4xMSqVvoucZjonVDA\/640?wx_fmt=jpeg'\" data-recalc-dims=\"1\" \/><span style=\"font-size: 16px;letter-spacing: 1px;text-align: justify;text-indent: 0em;\"> <\/span><span style=\"font-size: var(--articleFontsize);letter-spacing: 0.034em;text-align: justify;text-indent: 0em;\"><\/span><\/p>\n<p style=\"text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-family: \u7b49\u7ebf;font-variant: normal;text-transform: none;font-size: 16px;letter-spacing: 1px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010462\" data-ratio=\"0.4060975609756098\" data-type=\"png\" data-w=\"820\" height=\"224 .79998779296875\" width=\"553 .5400390625\" style=\"height: auto !important;\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/3_d1pMTSsSvS0Qv11tBpWNHEn31fHGKg.png?resize=553%2C224\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LQKv874JEq4N5e4TGSuqr4ODzrwC5pYtq871jbU3pRcyoPxd1pMTSsSvS0Qv11tBpWNHEn31fHGKg\/640?wx_fmt=png'\" data-recalc-dims=\"1\" \/><\/span><\/p>\n<p style=\"text-align: justify;font-size: 10.5pt;font-family: \u7b49\u7ebf;font-weight: normal;margin-left: 21pt;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;font-family: Wingdings;font-variant: normal;text-transform: none;color: rgb(237, 125, 49);\">l<\/span><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u9898\u76ee\uff1ascNovel\uff1a\u4e00\u79cd\u57fa\u4e8e\u6df1\u5ea6\u5b66\u4e60\u7684\u53ef\u6269\u5c55\u7f51\u7edc\uff0c\u7528\u4e8e\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u5b66\u4e2d\u53d1\u73b0\u65b0\u9896\u7a00\u6709\u7ec6\u80de<\/span><\/span><\/p>\n<p style=\"text-align: justify;font-size: 10.5pt;font-family: \u7b49\u7ebf;font-weight: normal;margin-left: 21pt;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;font-family: Wingdings;font-variant: normal;text-transform: none;color: rgb(237, 125, 49);\">l<\/span><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u6742\u5fd7\uff1aBrief Bioinform<\/span><\/span><\/p>\n<p style=\"text-align: justify;font-size: 10.5pt;font-family: \u7b49\u7ebf;font-weight: normal;margin-left: 21pt;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;font-family: Wingdings;font-variant: normal;text-transform: none;color: rgb(237, 125, 49);\">l<\/span><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u5f71\u54cd\u56e0\u5b50\uff1aIF=9.5<\/span><\/span><\/p>\n<p style=\"text-align: justify;font-size: 10.5pt;font-family: \u7b49\u7ebf;font-weight: normal;margin-left: 21pt;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;font-family: Wingdings;font-variant: normal;text-transform: none;color: rgb(237, 125, 49);\">l<\/span><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u53d1\u8868\u65f6\u95f4\uff1a2024\u5e74<\/span><span style=\"font-size: 16px;font-family: "Times New Roman";font-variant: normal;text-transform: none;\">2<\/span><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u6708<\/span><\/span><\/p>\n<p style=\"text-align: justify;font-size: 10.5pt;font-family: \u7b49\u7ebf;font-weight: normal;margin-left: 21pt;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\"><span style=\"outline: 0px;font-size: 16px;font-weight: 700;text-indent: -28px;letter-spacing: 0.544px;font-family: system-ui, -apple-system, "system-ui", "Helvetica Neue", "PingFang SC", "Hiragino Sans GB", "Microsoft YaHei UI", "Microsoft YaHei", Arial, sans-serif;background-color: rgb(255, 255, 255);color: rgb(0, 82, 255);\"><span style=\"outline: 0px;letter-spacing: 0.544px;\"><\/span><\/span><\/span><\/span><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"line-height: 150%;font-family: 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none;\">2009\u5e74Tang\u7b49\u4eba\u5efa\u7acb\u5355\u7ec6\u80deRNA\u6d4b\u5e8f\uff08scRNA-seq\uff09\uff0cscRNA-seq\u80fd\u591f\u5206\u6790\u5355\u4e2a\u7ec6\u80de\uff0c\u4e3a\u7ec6\u80de\u5f02\u8d28\u6027\u63d0\u4f9b\u6d1e\u5bdf\uff0c\u5e76\u5df2\u88ab\u5e7f\u6cdb\u5e94\u7528\u4e8e\u751f\u7269\u4f53\u56fe\u8c31\u751f\u6210\u3001COVID\u5206\u6790\u3001\u764c\u75c7\u7814\u7a76\u3001\u53d1\u80b2\u751f\u7269\u5b66\u7814\u7a76\u7b49\u3002\u5728\u5355\u7ec6\u80de\u7814\u7a76\u4e2d\uff0c\u4f20\u7edf\u4e0a\u901a\u8fc7\u5bf9\u7ec6\u80de\u70b9\u5206\u7ec4\u7136\u540e\u4f7f\u7528\u57fa\u56e0\u8fdb\u884c\u6807\u8bb0\u6765\u8fdb\u884c\u3002\u7531\u4e8e\u7ec6\u80de\u56fe\u8c31\u4ea7\u91cf\u6fc0\u589e\u53ca\u5176\u5728\u901f\u5ea6\u3001\u51c6\u786e\u6027\u548c\u7528\u6237\u53cb\u597d\u6027\u65b9\u9762<\/span><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 0);\">\u7684\u4f18\u52bf\uff0c\u81ea\u52a8\u6ce8\u91ca\u5de5\u5177\u5f00\u59cb\u5360\u636e\u4e3b\u5bfc\u5730\u4f4d\u3002\u5de5\u5177\u9700\u8981\u51c6\u786e\u5730\u67e5\u8be2\u7ec6\u80de\u5206\u7c7b\uff0c\u8fd8\u8981\u8bc6\u522b\u53c2\u8003\u6570\u636e\u96c6\u4e2d\u4e0d\u5b58\u5728\u7684\u65b0\u578b\u7ec6\u80de\u7c7b\u578b\u3002\u7136\u800c\uff0c\u5927\u591a\u6570\u4ee5\u5f80\u7684\u81ea\u52a8\u6ce8\u91ca\u7814\u7a76\u4e3b\u8981\u96c6\u4e2d\u5728\u901a\u7528\u7ec6\u80de\u7c7b\u578b\u6ce8\u91ca\u4e0a\uff0c\u5f88\u5c11\u5173\u6ce8\u65b0\u578b\u7a00\u6709\u7ec6\u80de\u7684\u53d1\u73b0\u3002\u4ee5\u5f80\u7814\u7a76\u4e2d\u5e76\u6ca1\u6709\u4e13\u6ce8\u4e8e\u65b0\u578b\u7a00\u6709\u7ec6\u80de\u68c0\u6d4b\uff0c\u7279\u5f81\u63d0\u53d6\u65b9\u6cd5\u8fc7\u4e8e\u7b80\u5355\uff0c\u5bfc\u81f4\u751f\u6210\u7684\u65b0\u578b\u7a00\u6709\u7ec6\u80de\u7279\u5f81\u53ef\u80fd\u4e22\u5931\u4fe1\u606f\u3002\u4f5c\u8005\u63d0\u51fa\u4e86\u4e00\u4e2a\u96c6\u6210\u7684\u795e\u7ecf\u7f51\u7edc\u6846\u67b6scNovel\uff0c\u5e76\u5b9e\u73b0\u4e86\u826f\u597d\u7684\u53ef\u6269\u5c55\u6027\u548c\u9c81\u68d2\u6027\u3002<\/span> 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style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 0);\">\u7ea6<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(0, 0, 0);\">1.5m\u7ec6\u80de\uff09<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 0);\">\uff08\u88681\uff09\u3002\u4f5c\u8005\u7ed3\u5408\u4e86\u5177\u6709\u4e0d\u540c\u590d\u6742\u5ea6\u548c\u6392\u5e8f\u89c4\u5219\u7684\u6570\u636e\u96c6\uff0c\u4ee5\u663e\u793a\u672c\u7814\u7a76\u63d0\u51fa\u7684\u6a21\u578b\u7684\u6709\u6548\u6027\u548c\u6cdb\u5316\u6027\u3002<\/span><\/span><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u8868<\/span><span style=\"font-size: 16px;font-family: "Times New Roman";font-variant: normal;text-transform: none;\">1 <\/span><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u4e0d\u540c\u89c4\u6a21\u7684\u6d4b\u5e8f\u6570\u636e\u96c6<\/span><\/span><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-family: \u7b49\u7ebf;font-variant: normal;text-transform: none;font-size: 16px;letter-spacing: 1px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010464\" data-ratio=\"0.3490740740740741\" data-type=\"png\" data-w=\"1080\" height=\"193 .13998413085938\" width=\"553 .2100219726562\" style=\"height: auto !important;\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/4_lib7hIJnRRu73efchd0SM6aZsrh02g.png?resize=553%2C193\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LQKv874JEq4N5e4TGSuqr4O0icVOOmB968kC6BGxktVhlyOYAlib7hIJnRRu73efchd0SM6aZsrh02g\/640?wx_fmt=png'\" data-recalc-dims=\"1\" \/><\/span><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;font-size: 16px;letter-spacing: 1px;\">\u7814\u7a76\u601d\u8def<\/span><\/p>\n<p style=\"text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 0);\">\u4f5c\u8005\u63d0\u51fa\u4e86<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(0, 0, 0);\">scNovel<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 0);\">\uff0c\u5176\u57fa\u672c\u7ed3\u6784\u662f\u4e00\u4e2a\u57fa\u4e8e\u6df1\u5ea6\u795e\u7ecf\u7f51\u7edc\u7684\u5206\u7c7b\u5668\u3002scNovel\u4ee5\u5355\u7ec6\u80de\u57fa\u56e0\u8868\u8fbe\u4f5c\u4e3a\u8f93\u5165\uff0c\u901a\u8fc7\u7ec6\u80de\u7c7b\u522b\u7684\u6982\u7387\u548c\u9608\u503c\u03bb\u8f93\u51fa\u65b0\u7ec6\u80de\u7684\u68c0\u6d4b\u7ed3\u679c\u3002scNovel\u5305\u542b\u4e24\u4e2a\u9636\u6bb5\uff0c\u5728\u8bad\u7ec3\u9636\u6bb5\uff0c\u4f5c\u8005\u91c7\u7528\u4ea4\u53c9\u71b5\u635f\u5931\u6765\u8bad\u7ec3\u6a21\u578b\uff0c\u5728\u5206\u7c7b\u5668\u540e\u8f93\u51fa\u7ec6\u80de\u7c7b\u578b\u7684\u6982\u7387\u9884\u6d4b\u3002\u5728\u67e5\u8be2\u9636\u6bb5\uff0c\u5982\u679c\u6982\u7387\u5c0f\u4e8e\u9608\u503c\uff0c\u5219\u76f8\u5e94\u7684\u5355\u5143\u683c\u786e\u5b9a\u4e3a\u65b0\u3002\u4e00\u65e6\u8003\u8651\u7684\u5206\u6570\u8d85\u8fc7\u4e86\u9608\u503c\u03bb\uff08\u901a\u5e38\u5b9a\u4e49\u4e3a0.5\uff09\uff0c\u6211\u4eec\u5c31\u786e\u5b9a\u5b83\u662f\u65b0\u7684\u3002\u901a\u8fc7\u7efc\u5408\u5b9e\u9a8c\uff0cscNovel\u7684\u9884\u6d4b\u80fd\u529b\u5177\u6709\u826f\u597d\u7684\u5e94\u7528\u524d\u666f\u3002<\/span>    <\/span><o:page><\/o:page><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-family: \u7b49\u7ebf;font-variant: normal;text-transform: none;font-size: 16px;letter-spacing: 1px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010466\" data-ratio=\"0.4842592592592593\" data-type=\"png\" data-w=\"1080\" height=\"268 .20001220703125\" width=\"553 .280029296875\" style=\"height: auto !important;\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/5_ocTNXcMbCdcMIr8Q0UTChXmibgDQjg.png?resize=553%2C268\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LQKv874JEq4N5e4TGSuqr4OLpjYjociaWNNJ5lTdwNen2KNiaZocTNXcMbCdcMIr8Q0UTChXmibgDQjg\/640?wx_fmt=png'\" data-recalc-dims=\"1\" \/><\/span><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u56fe1 <\/span><span style=\"font-size: 16px;font-family: "Times New Roman";font-variant: normal;text-transform: none;\">scNovel<\/span><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u6a21\u578b\u6846\u67b6<\/span><\/span><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;font-size: 16px;letter-spacing: 1px;\">\u4e3b\u8981\u7ed3\u679c<\/span><\/p>\n<p style=\"text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: bold;\">1. <\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u6a21\u578b\u6027\u80fd\u7684\u7efc\u5408\u8bc4\u4ef7<\/span><\/span><\/p>\n<p style=\"text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u4f5c\u8005\u5c06scNovel\u4e0e\u73b0\u6709\u7684\u7ec6\u80de\u7c7b\u578b\u5206\u7c7b\u5de5\u5177\u8fdb\u884c\u4e86\u6027\u80fd\u6bd4\u8f83\u3002\u6570\u636e\u96c6\u9009\u62e9\u6db5\u76d6\u4e86\u5e7f\u6cdb\u4f7f\u7528\u7684\u5355\u7ec6\u80de\u6d4b\u5e8f\u6280\u672f\uff0c\u5305\u62ec10Xv2\u548c10Xv3\u7b49\u3002\u4e0e\u4ee5\u524d\u7684\u6a21\u578b\u76f8\u6bd4\uff0c\u4f5c\u8005\u63d0\u51fa\u7684scNovel\u5728\u4e0d\u540c\u6570\u636e\u96c6\u4e0a\u7684\u65b0\u578b\u7a00\u6709\u7ec6\u80de\u53d1\u73b0\u4efb\u52a1\u4e2d\uff0c\u901a\u8fc7\u62e5\u6709\u6700\u4f4e\u7684FPR95\u5206\u6570\u3001\u6700\u9ad8\u7684AUROC\u548c\u6700\u9ad8\u7684AUPR\u5206\u6570\uff0c\u663e\u8457\u63d0\u9ad8\u4e86\u5e73\u5747\u6027\u80fd\u3002\u5f53\u65b0\u578b\u7c7b\u522b\u6570\uff08C<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\"><sup>novel<\/sup><\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\uff09\u7b49\u4e8e1\u65f6\uff0cscNovel\u7684AUROC\u8fbe\u523096.33%\uff0c\u5927\u5e45\u9886\u5148\u5176\u4ed6\u65b9\u6cd5\u3002\u6240\u6709\u7ed3\u679c\u4e00\u81f4\u8868\u660escNovel\u5728\u5927\u591a\u6570\u60c5\u51b5\u4e0b\u90fd\u663e\u8457\u4f18\u4e8e\u5176\u4ed6\u65b9\u6cd5\uff0c\u8868\u660e\u4e86\u91c7\u7528\u7684\u795e\u7ecf\u7f51\u7edc\u5bf9\u4e8e\u5355\u7ec6\u80de\u6d4b\u5e8f\u7279\u5f81\u63d0\u53d6\u8868\u73b0\u51fa\u4e86\u9c81\u68d2\u6027\uff0c\u7279\u522b\u9002\u7528\u4e8e\u65b0\u578b\u7a00\u6709\u7ec6\u80de\u7279\u5f81\u63d0\u53d6\uff08\u56fe2\uff09\u3002<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 255);font-weight: bold;\">\u5728\u7efc\u5408\u8bc4\u4ef7\u4e2d\uff0cscNovel\u53d6\u5f97\u4e86\u6700\u4f18\u7684\u5206\u7c7b\u6027\u80fd\u3002<\/span>    <\/span><o:page><\/o:page><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-family: \u7b49\u7ebf;font-variant: normal;text-transform: none;font-size: 16px;letter-spacing: 1px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010465\" data-ratio=\"0.907673860911271\" data-type=\"png\" data-w=\"834\" height=\"501 .8699951171875\" width=\"552 .9400024414062\" style=\"height: auto !important;\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/6_FvSnSpUvZrTHttfOT7RQQvtkrzkIwg.png?resize=552%2C501\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LQKv874JEq4N5e4TGSuqr4O7dD4u6c5A3kSypX4CY3qwaBsFvSnSpUvZrTHttfOT7RQQvtkrzkIwg\/640?wx_fmt=png'\" data-recalc-dims=\"1\" \/><\/span><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;letter-spacing: 1px;\">\u56fe2 \u6027\u80fd\u6d4b\u8bd5\u548c\u7d2b\u767e\u5408\u6570\u636e\u96c6\u4e0a\u7684\u53ef\u89c6\u5316<\/span><\/p>\n<p style=\"text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: bold;\">2. <\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u4e0d\u540c\u6a21\u5f0f\u4e0b\u4e0d\u540c\u65b0\u7c7b\u522b\u6570\u91cf\u7684\u4e00\u81f4\u6027\u6027\u80fd<\/span><\/span><\/p>\n<p style=\"text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u4f5c\u8005\u901a\u8fc7\u4e0d\u540c\u7684\u65b0\u578b\u7ec6\u80de\u7c7b\u522b\u6570\u91cfC<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\"><sup>novel<\/sup><\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u5728\u4e0d\u540c\u6a21\u5f0f\u4e0b\u63a2\u8ba8\u4e86\u6a21\u578b\u7684\u6027\u80fd\u3002\u9996\u5148\u5c55\u793a\u4e86\u6a21\u578b\u5728\u56db\u79cd\u4e0d\u540c\u67e5\u8be2\u6a21\u5f0f\u4e0b\u7684\u6027\u80fd\uff1a\u5229\u7528\u6700\u5927\u9884\u6d4b\u6982\u7387\u4f5c\u4e3a\u5206\u6570\u7684S<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\"><sup>MSP<\/sup><\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\uff1b\u53ea\u4f7f\u7528Tminus\u6761\u5f62\u7801\u9884\u5904\u7406\u7684S<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\"><sup>ODIN<\/sup><\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\uff1b\u4f9d\u6b21\u4f7f\u7528T<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\"><sub>minus<\/sub><\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u548cT<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\"><sub>plus<\/sub><\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u6761\u5f62\u7801\u9884\u5904\u7406\u7684S<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\"><sup>SEQ<\/sup><\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\uff1b\u540c\u65f6\u4f7f\u7528T<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\"><sub>minus<\/sub><\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u548cT<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\"><sub>plus<\/sub><\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u6761\u5f62\u7801\u9884\u5904\u7406\u7684S<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\"><sup>SIM<\/sup><\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u3002\u901a\u8fc7\u8be6\u7ec6\u7684\u5256\u6790\u7814\u7a76\uff0c\u5f97\u51fa\u7ed3\u8bba\uff0cS<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\"><sup>SIM<\/sup><\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u5e94\u8be5\u662f\u65b0\u578b\u7a00\u6709\u7ec6\u80de\u7c7b\u578b\u53d1\u73b0\u4efb\u52a1\u7684\u6700\u4f73\u6a21\u5f0f\u3002\u63a5\u7740\uff0c\u4f5c\u8005\u8be6\u7ec6\u7814\u7a76\u4e86\u5728S<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\"><sup>SIM<\/sup><\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u6a21\u5f0f\u4e0b\u4e0d\u540cC<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\"><sup>novel<\/sup><\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u7684scNovel\u6027\u80fd\u3002\u603b\u4f53\u800c\u8a00\uff0cscNovel\u5728\u6240\u6709\u6570\u636e\u96c6\u4e0a\u90fd\u6709\u6700\u4f73\u7684\u5e73\u5747\u6027\u80fd\u3002scNovel\u7684\u65b0\u578b\u7a00\u6709\u7ec6\u80de\u68c0\u6d4b\u6027\u80fd\u4e3b\u8981\u53d7\u7ec6\u80de\u7c7b\u578b\u5f71\u54cd\uff0c\u5e76\u4e14\u5bf9\u4e8e\u4e0d\u540c\u7684C<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\"><sup>novel<\/sup><\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u5177\u6709\u9c81\u68d2\u6027\u3002scNovel\u4e0eZilionis\u6570\u636e\u96c6\u4e2d\u65b0\u578b\u7ec6\u80de\u53d1\u73b0\u4efb\u52a1\u7684\u771f\u5b9e\u60c5\u51b5\u8fdb\u884c\u4e86UMAP\u53ef\u89c6\u5316\u6bd4\u8f83\u5206\u6790\uff0c\u7ed3\u679c\u8868\u660e\u4f5c\u8005\u63d0\u51fa\u7684scNovel\u65b9\u6cd5\u5728\u4e0d\u540cC<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\"><sup>novel<\/sup><\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u503c\u4e0b\u5b9e\u73b0\u4e86\u663e\u8457\u4e00\u81f4\u7684\u53ef\u89c6\u5316\u6027\u80fd\uff08\u56fe3\uff09\u3002<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 255);font-weight: bold;\">\u603b\u4e4b\uff0cscNovel\u5728\u4e0d\u540c\u65b0\u578b\u7ec6\u80de\u7c7b\u522b\u6570\u91cf\u548c\u4e0d\u540c\u6a21\u5f0f\u4e0b\u7684\u6027\u80fd\u5747\u5177\u6709\u66f4\u9ad8\u7684\u7a33\u5b9a\u6027\u3002<\/span>    <\/span><span style=\"text-indent: 0em;font-family: \u7b49\u7ebf;font-variant-numeric: normal;font-variant-east-asian: normal;font-variant-alternates: normal;font-size: 16px;letter-spacing: 1px;\">    <o:p> <\/o:p><\/span><span style=\"text-indent: 0em;font-size: 16px;letter-spacing: 1px;\">    <\/span><span style=\"text-indent: 0em;font-size: var(--articleFontsize);letter-spacing: 0.034em;\"><\/span><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-family: \u7b49\u7ebf;font-variant: normal;text-transform: none;font-size: 16px;letter-spacing: 1px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010463\" data-ratio=\"1.2677165354330708\" data-type=\"png\" data-w=\"635\" height=\"701 .9400024414062\" width=\"553 .739990234375\" style=\"height: auto !important;\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/7_u3SnIBLO3XSfXrZh92bGkfY1icoWOQ.png?resize=553%2C701\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LQKv874JEq4N5e4TGSuqr4OSDMtVT3lbibLeRCCxXYScQB8dQu3SnIBLO3XSfXrZh92bGkfY1icoWOQ\/640?wx_fmt=png'\" data-recalc-dims=\"1\" \/><\/span><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u56fe<\/span><span style=\"font-size: 16px;font-family: "Times New Roman";font-variant: normal;text-transform: none;\">3 <\/span><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u4e0d\u540c\u6570\u636e\u96c6\u4e0a\u7684\u6027\u80fd<\/span><\/span><\/p>\n<p style=\"text-align: justify;margin-left: 0pt;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: bold;\">3.<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u7a00\u6709\u7ec6\u80de\u7c7b\u578b\u8bc6\u522b\u7684\u4f18\u52bf<\/span><\/span><\/p>\n<p style=\"text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u5728\u771f\u5b9e\u5e94\u7528\u573a\u666f\u4e2d\uff0c\u7a00\u6709\u7ec6\u80de\u68c0\u6d4b\u5de5\u5177\u7684\u8bad\u7ec3\u548c\u5e94\u7528\u53ef\u4ee5\u5728\u5177\u6709\u4e0d\u540c\u6570\u636e\u96c6\u534f\u8bae\u548c\u5e73\u53f0\u4e0a\u8fdb\u884c\u3002\u4f5c\u8005\u6536\u96c6\u4e86\u6765\u81ea10Xv2\u300110Xv3\u3001Drop-Seq\u3001Cel-Seq\u3001InDrop\u548cSeq-Well\u7684PBMCbench\u6570\u636e\u96c6\uff0c\u4ee5\u8bc4\u4f30scNovel\u8de8\u5e73\u53f0\u68c0\u6d4b\u65b0\u578b\u7a00\u6709\u7ec6\u80de\u7684\u80fd\u529b\u3002\u4e0e\u5176\u4ed6\u6a21\u578b\u7684\u5bf9\u6bd4\u7ed3\u679c\u8868\u660e\u4e86scNovel\u5bf9\u8de8\u5e73\u53f0\u6ce8\u91ca\u4efb\u52a1\u4e2d\u7684\u6f5c\u5728\u969c\u788d\u5177\u6709\u9c81\u68d2\u6027\u3002\u540c\u65f6\u53d1\u73b0\u53ea\u6709scNovel\u548cscLearn\u6210\u529f\u68c0\u6d4b\u5230\u6240\u6709\u5de8\u6838\u7ec6\u80de\uff0c\u800cscmap-cell\u3001scmap-cluster\u548cscPred\u9519\u8fc7\u4e86\u90e8\u5206\u5de8\u6838\u7ec6\u80de\u3002\u4e0escLearn\u76f8\u6bd4\uff0c\u6211\u4eec\u63d0\u51fa\u7684scNovel\u6709\u66f4\u5c11\u7684\u5047\u9633\u6027\u9884\u6d4b\uff0c\u800cscLearn\u9519\u8bef\u5730\u5c06CD16+\u5355\u6838\u7ec6\u80de\u548c\u7ec6\u80de\u6bd2\u6027T\u7ec6\u80de\u5224\u65ad\u4e3a\u65b0\u578b\u3002\u6b64\u5916\uff0c\u6839\u636eAUROC\u66f2\u7ebf\uff0c\u4f5c\u8005\u53d1\u73b0scNovel\u65e0\u8bba\u5728\u4efb\u4f55FPR\u4e0b\u90fd\u6709\u6bd4\u6240\u6709\u5176\u4ed6\u6a21\u578b\u66f4\u597d\u7684TPR\uff08\u56fe4\uff09\u3002<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(0, 0, 255);font-weight: bold;\">scNovel\u5728\u8de8\u5e73\u53f0\u5f71\u54cd\u4e0b\u4fdd\u6301\u4e86\u5728\u65b0\u578b\u7a00\u6709\u7ec6\u80de\u7c7b\u578b\u53d1\u73b0\u4efb\u52a1\u4e2d\u7684\u5353\u8d8a\u6027\u80fd\u3002<\/span>    <\/span><o:page><\/o:page><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-family: \u7b49\u7ebf;font-variant: normal;text-transform: none;font-size: 16px;letter-spacing: 1px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010469\" data-ratio=\"0.7805362462760675\" data-type=\"png\" data-w=\"1007\" height=\"431 .5400390625\" width=\"552 .8800048828125\" style=\"height: auto !important;\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/8_ibfrCd6QLZxk6zLl2rBHj3GEgTCAgA.png?resize=552%2C431\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LQKv874JEq4N5e4TGSuqr4OUBRpy8sTWxJOrakdpibDFCSZFZibfrCd6QLZxk6zLl2rBHj3GEgTCAgA\/640?wx_fmt=png'\" data-recalc-dims=\"1\" \/><\/span><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u56fe<\/span><span style=\"font-size: 16px;font-family: "Times New Roman";font-variant: normal;text-transform: none;\">4 <\/span><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u5728\u751f\u6210\u65b0\u578b\u7f55\u89c1\u6570\u636e\u7684\u6027\u80fd\u8bc4\u4f30<\/span><\/span><\/p>\n<p style=\"text-align: justify;margin-left: 0pt;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: bold;\">4.<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u63d0\u9ad8scNovel\u7684\u53ef\u6269\u5c55\u6027<\/span><\/span><\/p>\n<p style=\"text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u5728\u771f\u5b9e\u4e16\u754c\u7684\u5355\u7ec6\u80de\u5206\u6790\u4e2d\uff0c\u8ba1\u7b97\u6548\u7387\u81f3\u5173\u91cd\u8981\uff0c\u88ab\u89c6\u4e3a\u5b9e\u73b0\u53ef\u6269\u5c55\u6027\u7684\u4e3b\u8981\u969c\u788d\u3002scNovel\u7684\u8fd0\u884c\u65f6\u95f4\u5728\u4e0d\u540c\u6837\u672c\u91cf\u7684\u6570\u636e\u96c6\u4e2d\u76f8\u5bf9\u4e00\u81f4\u3002\u5bf9\u4e8e\u8d85\u8fc730k\u7ec6\u80de\u7684\u6570\u636e\u96c6\uff0cscNovel\u76f8\u5bf9\u4e8e\u5176\u4ed6\u6a21\u578b\u5c06\u8fd0\u884c\u65f6\u95f4\u51cf\u5c11\u4e86\u591a\u8fbe25%\u3002\u5206\u6790\u663e\u793a\uff0c\u6a21\u578b\u7684\u8fd0\u884c\u65f6\u95f4\u4e3b\u8981\u53d7\u5230\u4e24\u4e2a\u56e0\u7d20\u7684\u5f71\u54cd\uff1a\u8ba1\u7b97\u548c\u6743\u91cd\u66f4\u65b0\uff0c\u4ee5\u53ca\u6570\u636e\u51c6\u5907\u9636\u6bb5\uff0c\u8fd9\u5728\u4e0d\u540c\u6570\u636e\u96c6\u4e2d\u4fdd\u6301\u4e0d\u53d8\u3002\u8f83\u5c0f\u7684\u6570\u636e\u96c6\u9700\u8981\u66f4\u9891\u7e41\u7684\u6570\u636e\u51c6\u5907\uff0c\u5bfc\u81f4\u8fd0\u884c\u65f6\u95f4\u66f4\u957f\u3002\u56e0\u6b64\uff0c\u6570\u636e\u96c6\u5927\u5c0f\u76f4\u63a5\u5f71\u54cd\u6a21\u578b\u7684\u603b\u8fd0\u884c\u65f6\u95f4\u3002\u4e3a\u4e86\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u6a21\u578b\u6027\u80fd\u5728\u5927\u578b\u3001\u4e0d\u5e73\u8861\u6570\u636e\u96c6\u4e0a\u7684\u9c81\u68d2\u6027\uff0c\u4f5c\u8005\u5c06scNovel\u5e94\u7528\u4e8e\u767e\u4e07\u89c4\u6a21\u7684scRNA-seq\u6570\u636e\u96c6COVID-19\u514d\u75ab\u56fe\u8c31\uff081,462,702\u4e2a\u7ec6\u80de\uff09\u3002\u7ed3\u679c\u8868\u660escNovel\u80fd\u591f\u51c6\u786e\u8bc6\u522b\u5728COVID-19\u6848\u4f8b\u4e2d\u72ec\u6709\u768410\u79cd\u65b0\u578b\u7a00\u6709\u7ec6\u80de\u7c7b\u578b\uff08\u56fe5\uff09\u3002<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(0, 0, 255);font-weight: bold;\">\u7ed3\u679c\u8868\u660escNovel\u5177\u6709\u9ad8\u5ea6\u53ef\u6269\u5c55\u6027\uff0c\u4ee5\u53ca\u5177\u6709\u5927\u89c4\u6a21\u5b9e\u9645\u5e94\u7528\u7684\u6f5c\u529b\u3002<\/span>    <\/span><span style=\"font-family: "Times New Roman";font-size: 16px;letter-spacing: 1px;text-indent: 0em;\">       <\/span><o:p style=\"font-family: "Times New Roman";font-size: 16px;letter-spacing: 1px;text-indent: 0em;\"> <\/o:p><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-family: \u7b49\u7ebf;font-variant: normal;text-transform: none;font-size: 16px;letter-spacing: 1px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010467\" data-ratio=\"1.0875370919881306\" data-type=\"png\" data-w=\"674\" height=\"601 .81005859375\" width=\"553 .3400268554688\" style=\"height: auto !important;\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/9_ibc6AUZeiaic4HJxSqDkDPxu0KYicg.png?resize=553%2C601\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LQKv874JEq4N5e4TGSuqr4OSR4wBxL3saRibMXF3xgtBLHQia9WoFibc6AUZeiaic4HJxSqDkDPxu0KYicg\/640?wx_fmt=png'\" data-recalc-dims=\"1\" \/><\/span><span style=\"font-size: 16px;letter-spacing: 1px;\">    <\/span><o:page><\/o:page><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u56fe<\/span><span style=\"font-size: 16px;font-family: "Times New Roman";font-variant: normal;text-transform: none;\">5 <\/span><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u65f6\u95f4\u590d\u6742\u5ea6\u4e0e\u6027\u80fd\u5206\u6790\u4ee5\u53ca\u65b0\u7ec6\u80de\u53d1\u73b0\u53ef\u89c6\u5316<\/span><\/span><\/p>\n<p style=\"text-align: justify;margin-left: 0pt;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;font-weight: bold;\">5.<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;\">\u514d\u75ab\u7ec6\u80de\u56fe\u8c31\u4e2d\u6f5c\u5728\u65b0\u578b\u4e9a\u578b\u7684\u53d1\u73b0\u548c\u529f\u80fd\u7814\u7a76<\/span><\/span><\/p>\n<p style=\"text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u7814\u7a76\u8868\u660e\uff0c\u5728\u751f\u7269\u533b\u5b66\u9886\u57df\uff0c\u5bf9\u7279\u5b9a\u7ec6\u80de\u7c7b\u578b\u7684\u9057\u4f20\u5f02\u8d28\u6027\u8fdb\u884c\u7ec6\u80de\u7c7b\u578b\u7279\u5f02\u6027\u5206\u6790\u975e\u5e38\u91cd\u8981\u3002\u7136\u800c\uff0c\u65b0\u578b\u7ec6\u80de\u7c7b\u578b\u7684\u68c0\u6d4b\u8fc7\u7a0b\u65e2\u8017\u65f6\u53c8\u9700\u8981\u5148\u9a8c\u77e5\u8bc6\u3002\u4f5c\u8005\u63d0\u51fa\u7684scNovel\u80fd\u591f\u81ea\u52a8\u53d1\u73b0\u65b0\u578b\u7a00\u6709\u7ec6\u80de\uff1a(1)\u68c0\u6d4b\u67e5\u8be2\u96c6\u7684\u65b0\u578b\u7ec6\u80de\uff1b(2)\u4f7f\u7528Leiden\u805a\u7c7b\u751f\u6210\u7ec6\u80de\u7fa4\u96c6\uff1b(3)\u5229\u7528\u65b0\u578b\u7ec6\u80de\u7fa4\u96c6\u8fdb\u884c\u8fdb\u4e00\u6b65\u5206\u6790\u3002\u901a\u8fc7\u5c06scNovel\u5e94\u7528\u4e8e\u516c\u5f00\u7684COVID-19\u6570\u636e\u96c6\uff0c\u4f5c\u8005\u5c55\u793a\u4e86\u7ec6\u80de\u7c7b\u578b\u548c\u60a3\u8005\u6ce8\u91ca\u7684UMAP\u53ef\u89c6\u5316\uff0c\u5e76\u6210\u529f\u5730\u68c0\u6d4b\u51faAT1\u548cAT2\u4f5c\u4e3a\u65b0\u578b\u7ec6\u80de\u3002\u6b64\u5916\uff0c\u901a\u8fc7\u5c55\u793a\u65b0\u578b\u7ec6\u80de\u7fa4\u96c6\u7684\u6700\u9ad8\u57fa\u56e0\u8868\u8fbe\u53ca\u5176\u5173\u7cfb\uff0c\u4f5c\u8005\u53d1\u73b0\u67d0\u4e9b\u7fa4\u96c6\u53ef\u80fd\u662f\u5de8\u566c\u7ec6\u80de\u7684\u4e9a\u578b\uff0c\u5e76\u8fdb\u4e00\u6b65\u5206\u6790\u4e86\u8fd9\u4e9b\u7fa4\u96c6\u4e0eCOVID-19\u4e4b\u95f4\u7684\u5173\u7cfb\u3002\u672c\u7814\u7a76\u4e0d\u4ec5\u51c6\u786e\u8bc6\u522b\u4e86\u72ec\u7279\u7684\u7ec6\u80de\u7c7b\u578b\uff0c\u8fd8\u901a\u8fc7GO\u5206\u6790\u63a2\u8ba8\u4e86\u4e0d\u540cCOVID\u72b6\u6001\u4e0b\u5de8\u566c\u7ec6\u80de\u751f\u7269\u9014\u5f84\u7684\u53d8\u5316\uff0c\u663e\u793a\u4e86scNovel\u4f5c\u4e3a\u52a0\u901f\u672a\u6765\u5927\u6d41\u884c\u75c5\u6216\u75be\u75c5\u8bca\u65ad\u548c\u5e94\u7b54\u7684\u5173\u952e\u5de5\u5177\u7684\u6f5c\u529b\uff08\u56fe6\uff09\u3002<\/span><span style=\"font-size: 16px;line-height: 150%;font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(0, 0, 255);font-weight: bold;\">scNovel\u80fd\u591f\u81ea\u52a8\u53d1\u73b0\u5e76\u6ce8\u91ca\u65b0\u578b\u7f55\u89c1\u7ec6\u80de\u3002<\/span>    <\/span><o:page><\/o:page><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-family: \u7b49\u7ebf;font-variant: normal;text-transform: none;font-size: 16px;letter-spacing: 1px;\"><img decoding=\"async\" loading=\"lazy\" class=\"rich_pages wxw-img\" data-imgfileid=\"100010468\" data-ratio=\"1.0261519302615194\" data-type=\"png\" data-w=\"803\" height=\"567 .739990234375\" width=\"553 .280029296875\" style=\"height: auto !important;\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/10_W72NRgFv7xOcYPqCYy7h6keclEK8PA.png?resize=553%2C567\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/hud5kpqc1LQKv874JEq4N5e4TGSuqr4OZhwUsqricWQtNMhNUIMibPmmmeW72NRgFv7xOcYPqCYy7h6keclEK8PA\/640?wx_fmt=png'\" data-recalc-dims=\"1\" \/><\/span><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"font-size: 16px;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u56fe<\/span><span style=\"font-size: 16px;font-family: "Times New Roman";font-variant: normal;text-transform: none;\">6 UMAP\u53ef\u89c6\u5316\u548c\u805a\u7c7b\u5206\u6790<\/span><\/span><\/p>\n<p style=\"text-align: center;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"line-height: 150%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;font-weight: bold;font-size: 16px;letter-spacing: 1px;\">\u6587\u7ae0\u5c0f\u7ed3<\/span><\/p>\n<p style=\"text-align: justify;text-indent: 0em;margin-top: 8px;margin-bottom: 0px;line-height: 1.6em;\"><span style=\"font-size: 16px;letter-spacing: 1px;\"><span style=\"letter-spacing: 1px;font-size: 16px;line-height: 200%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u4f5c\u8005\u662f\u7b2c\u4e00\u4e2a\u4e13\u6ce8\u4e8e\u65b0\u578b\u7a00\u6709\u7ec6\u80de\u53d1\u73b0\u7684\uff0c\u5e76\u63d0\u51fa\u4e86\u7b2c\u4e00\u4e2a\u76f8\u5e94\u7684\u81ea\u52a8\u68c0\u6d4b\u6a21\u578bscNovel\u3002\u901a\u8fc7\u5728\u4e0d\u540c\u89c4\u6a21\u3001\u4e0d\u540c\u751f\u6210\u534f\u8bae\u548c\u4e0d\u540cC<\/span><span style=\"letter-spacing: 1px;font-size: 16px;line-height: 200%;font-family: "Times New Roman";font-variant: normal;text-transform: none;\"><sup>novel<\/sup><\/span><span style=\"letter-spacing: 1px;font-size: 16px;line-height: 200%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;\">\u7684\u591a\u4e2ascRNA-seq\u6570\u636e\u96c6\u4e0a\u8fdb\u884c\u5e7f\u6cdb\u5b9e\u9a8c\uff0c\u4f5c\u8005\u5c55\u793a\u4e86\u6709\u6548\u7684\u65b0\u578b\u7a00\u6709\u7ec6\u80de\u53d1\u73b0\u80fd\u529b\u3002\u540c\u65f6\u8fd8\u5c55\u793a\u4e86scNovel\u5728\u4e0d\u540c\u89c4\u6a21\u6570\u636e\u96c6\u4e0a\u7684\u5feb\u901f\u8fd0\u884c\u901f\u5ea6\uff0c\u8bc1\u660e\u4e86\u5176\u53ef\u6269\u5c55\u6027\u3002\u6b64\u5916\uff0c\u4f5c\u8005\u5728\u767e\u4e07\u7ea7\u522b\u7684\u6570\u636e\u96c6\u4e0a\u8bc4\u4f30\u4e86\u8be5\u6a21\u578b\uff0c\u8fdb\u4e00\u6b65\u5c55\u793a\u4e86\u5176\u53ef\u6269\u5c55\u6027\u548c\u65b0\u578b\u7a00\u6709\u7ec6\u80de\u53d1\u73b0\u80fd\u529b\u3002<\/span><span style=\"letter-spacing: 1px;font-size: 16px;line-height: 200%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;background: rgb(255, 255, 0);\">\u5c0f\u9014\u70ed\u60c5\u6b22\u8fce\u81f4\u529b\u4e8e\u4e34\u5e8a\u533b\u5b66\u548c\u836f\u7269\u7814\u7a76\u7684\u540c\u4ec1\uff0c\u4e00\u540c\u5229\u7528\u6df1\u5ea6\u5b66\u4e60\u4e0e\u6d4b\u5e8f\u5206\u6790\u6570\u636e\uff0c\u6253\u5f00\u9ad8\u5f71\u54cd\u529b\u5b66\u672f\u8bba\u6587\u7684\u5927\u95e8\uff01\u8fd9\u662f\u6fc0\u53d1\u521b\u65b0\u601d\u7ef4\u3001\u6df1\u5316\u5b9e\u9a8c\u63a2\u7d22\u7684\u7edd\u4f73\u65f6\u673a\u3002<\/span><span style=\"letter-spacing: 1px;font-size: 16px;line-height: 200%;font-family: \u5b8b\u4f53;font-variant: normal;text-transform: none;color: rgb(255, 0, 0);font-weight: bold;background: rgb(255, 255, 0);\">\u8ba9\u6211\u4eec\u52c7\u6562\u9762\u5bf9\u79d1\u7814\u65b0\u6311\u6218\uff0c\u5c0f\u9014\u671f\u76fc\u4e0e\u4f60\u643a\u624b\u524d\u884c<\/span><span style=\"letter-spacing: 1px;font-size: 16px;line-height: 200%;font-family: "Times New Roman";font-variant: normal;text-transform: none;color: rgb(255, 0, 0);font-weight: bold;background: rgb(255, 255, 0);\">~<\/span>    <\/span><o:page><\/o:page><\/p>\n<p style=\"text-indent: 0px;margin-bottom: 0px;\"><span style=\"color: rgb(0, 122, 170);\"><strong><span style=\"color: rgb(0, 122, 170);letter-spacing: 0.578px;text-indent: 32px;text-wrap: wrap;background-color: rgb(255, 255, 255);font-size: 15px;\">\u5c0f\u679c\u8fd8<span style=\"color: rgb(0, 122, 170);background-color: rgb(255, 255, 255);font-size: 15px;letter-spacing: 0.578px;text-decoration: none solid rgba(0, 0, 0, 0.9);\">\u63d0\u4f9b\u601d\u8def\u8bbe\u8ba1\u3001\u5b9a\u5236\u751f\u4fe1\u5206\u6790\u3001\u6587\u732e\u601d\u8def\u590d\u73b0\uff1b\u6709\u9700\u8981\u7684\u5c0f\u4f19\u4f34\u6b22\u8fce\u76f4\u63a5\u626b\u7801\u54a8\u8be2\u5c0f\u679c\uff0c\u7aed\u8bda\u4e3a\u60a8\u7684\u79d1\u7814\u52a9\u529b\uff01<\/span><\/span><\/strong><\/span><\/p>\n<p style=\"margin-bottom: 0px;\"><br \/><\/p>\n<section style=\"font-size: 15px;padding-right: 2px;padding-left: 2px;margin-bottom: 0px;\">\n<section style=\"text-align: center;justify-content: center;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;flex: 0 0 auto;height: auto;border-color: rgb(114, 114, 114);border-width: 1px;border-style: solid;box-shadow: rgb(194, 209, 255) -5px 5px 0px;align-self: flex-start;\">\n<section style=\"justify-content: center;display: flex;flex-flow: row;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 42.6829%;vertical-align: middle;box-shadow: rgb(43, 65, 110) 0px 0px 0px;flex: 0 0 auto;height: auto;padding-left: 10px;align-self: center;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;line-height: 0;transform: translate3d(20px, 0px, 0px);\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;width: 75%;height: auto;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-imgfileid=\"100017770\" data-ratio=\"1\" data-s=\"300,640\" data-type=\"jpeg\" data-w=\"430\" style=\"vertical-align: middle;width: 100%;height: auto !important;\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/2_B2jkicacLzPjw4xMSqVvoucZjonVDA-62.jpg?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_jpg\/zcicibWZessAxVYfSsM0wdf9d3RpNiaTcHohxPNEVs2VFhPMukpU8lchxrvcB2jkicacLzPjw4xMSqVvoucZjonVDA\/640?wx_fmt=jpeg'&from=appmsg\" data-recalc-dims=\"1\" \/><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: 56.9106%;flex: 0 0 auto;height: auto;align-self: center;\">\n<section style=\"line-height: 2;letter-spacing: 1px;color: rgb(43, 65, 110);\" powered-by=\"xiumi.us\">\n<p style=\"margin-bottom: 2px;\"><strong>\u5b9a\u5236\u751f\u4fe1\u5206\u6790<\/strong><\/p>\n<p style=\"margin-bottom: 2px;\"><strong>\u670d\u52a1\u5668\u79df\u8d41<\/strong><\/p>\n<p><strong>\u626b\u7801\u54a8\u8be2\u5c0f\u679c<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img\" data-galleryid=\"\" data-imgfileid=\"100017513\" data-ratio=\"0.7621359223300971\" data-s=\"300,640\" data-type=\"png\" data-w=\"618\" style=\"height: auto !important;\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2024\/06\/12_XiafCUEp1NqZoBA3F9mvRcJR4PQ1Tw-2.png?w=640\" onerror=\"this.src='https:\/\/mmbiz.qpic.cn\/sz_mmbiz_png\/zcicibWZessAyZkFgOs95yxYHqY7n8a8k4wWKhXgwQvZVTwDhgYYDDu7asGXiafCUEp1NqZoBA3F9mvRcJR4PQ1Tw\/640?wx_fmt=png&from=appmsg'\" data-recalc-dims=\"1\" \/><span style=\"letter-spacing: 0.034em;\"><\/span><\/p>\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;line-height: 0;\" powered-by=\"xiumi.us\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><br \/><\/section>\n<\/section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;text-align: left;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 10%;flex: 0 0 auto;height: auto;align-self: flex-end;padding-right: 2px;padding-left: 2px;\">\n<section style=\"margin: 10px 0% 2px;transform: translate3d(2px, 0px, 0px);\" powered-by=\"xiumi.us\">\n<section style=\"font-size: 16px;color: rgb(58, 66, 94);line-height: 1;letter-spacing: 5px;text-align: center;\">\n<p><strong>\u5f80\u671f\u56de\u987e<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"height: 3px;background-color: rgb(95, 156, 239);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<section style=\"margin-top: 2px;margin-right: 0%;margin-left: 0%;text-align: center;line-height: 0.8;font-size: 9px;\" powered-by=\"xiumi.us\">\n<section style=\"width: 0px;display: inline-block;border-top: 0.8em solid rgb(58, 66, 94);border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: auto;flex: 100 100 0%;align-self: flex-end;height: auto;\">\n<section style=\"margin-right: 0%;margin-left: 0%;\" powered-by=\"xiumi.us\">\n<section style=\"height: 3px;background-color: rgb(95, 156, 239);\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<section style=\"margin-top: 2px;margin-right: 0%;margin-left: 0%;text-align: center;line-height: 0.8;font-size: 9px;\" powered-by=\"xiumi.us\">\n<section style=\"width: 0px;display: inline-block;border-top: 0.8em solid rgba(255, 255, 255, 0);border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"min-height: 40px;margin: 10px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"width: 100%;margin-right: auto;margin-bottom: -10px;margin-left: auto;\">\n<table width=\"100%\">\n<tbody>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:0\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:0.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;box-shadow: rgb(0, 0, 0) 0px 0px 0px;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>01<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247497780&idx=2&sn=7eee90af6f387e4153bba13028e545a1&chksm=cf7f68f1f808e1e7dfb3a0597ef442e5c6e700ecf6ee5a035c766a4c7486c12eabd0ab218ea6&scene=21#wechat_redirect\" textvalue=\"1024G\u5b58\u50a8\u7684\u751f\u4fe1\u670d\u52a1\u5668\uff0c\u4e24\u4eba\u6210\u56e2\uff0c1\u4eba\u514d\u5355\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">1024G\u5b58\u50a8\u7684\u751f\u4fe1\u670d\u52a1\u5668\uff0c\u4e24\u4eba\u6210\u56e2\uff0c1\u4eba\u514d\u5355\uff01<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:1\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:1.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>02<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247498878&idx=1&sn=fc34ed3f1d15d060bbaf8166adcebd58&chksm=cf7f6cbbf808e5ad0b5417e50ed75cfbd1b3a83ac43b97f1dfa718c822878a9a004990075133&scene=21#wechat_redirect\" textvalue=\"\u5355\u4e2a\u6570\u636e\u5e93\u7528\u817b\u4e86\uff1f\u591a\u6570\u636e\u5e93\u201c\u7ec4\u5408\u62f3\u201d\u5e26\u4f60\u6253\u5f00\u514d\u75ab\u6d78\u6da6\u65b0\u601d\u8def\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u5355\u4e2a\u6570\u636e\u5e93\u7528\u817b\u4e86\uff1f\u591a\u6570\u636e\u5e93\u201c\u7ec4\u5408\u62f3\u201d\u5e26\u4f60\u6253\u5f00\u514d\u75ab\u6d78\u6da6\u65b0\u601d\u8def\uff01<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:2\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:2.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>03<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247498673&idx=1&sn=1e09b74a836c1e64a62ae1f66eeb3f93&chksm=cf7f6b74f808e262de70be43fd73bf5fefdc0914e525eb2032f741a0152e619689cedc76946f&scene=21#wechat_redirect\" textvalue=\"\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u7684\u51c6\u5907\u5de5\u4f5c\uff0cGWAS\u6570\u636e\u7684\u7f51\u7ad9\u4e0b\u8f7d\u65b9\u6cd5\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"11\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u5b5f\u5fb7\u5c14\u968f\u673a\u5316\u7684\u51c6\u5907\u5de5\u4f5c\uff0cGWAS\u6570\u636e\u7684\u7f51\u7ad9\u4e0b\u8f7d\u65b9\u6cd5<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<tr opera-tn-ra-comp=\"_$.pages:0.layers:0.comps:4.classicTable1:3\" powered-by=\"xiumi.us\">\n<td colspan=\"1\" rowspan=\"1\" opera-tn-ra-cell=\"_$.pages:0.layers:0.comps:4.classicTable1:3.td@@0\" style=\"border-color: rgb(62, 62, 62);border-style: none;padding: 0px;\" width=\"100.0000%\">\n<section>\n<section style=\"display: flex;flex-flow: row;margin-top: 10px;margin-right: 0%;margin-left: 0%;justify-content: flex-start;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: middle;width: auto;min-width: 10%;height: auto;flex: 0 0 auto;align-self: center;\">\n<section style=\"font-size: 19px;color: rgb(95, 156, 239);line-height: 1;\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><strong>04<\/strong><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;flex: 100 100 0%;align-self: center;height: auto;\">\n<section style=\"color: rgb(140, 140, 140);\" powered-by=\"xiumi.us\">\n<p style=\"text-wrap: wrap;\"><span style=\"color: rgb(224, 224, 224);\">\uff5c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=Mzg3OTg3MjQyNg==&mid=2247498517&idx=1&sn=fa3c0104cee316982fe8162b79fe234f&chksm=cf7f6bd0f808e2c6cf979704bf883cfb5480444604f90da61dc286e7541fa5bb49df0a2fb58a&scene=21#wechat_redirect\" textvalue=\"\u8ddf\u7740\u5c0f\u679c\u5b66\u590d\u73b0-\u624b\u628a\u624b\u5e26\u4f60\u62ff\u4e0bIF=46.9Nature \u7ea7\u522b\u7684\u4e3b\u6210\u5206\u5206\u6790\uff08PCA\uff09\u56fe\uff01\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u8ddf\u7740\u5c0f\u679c\u5b66\u590d\u73b0-\u624b\u628a\u624b\u5e26\u4f60\u62ff\u4e0bIF=46.9Nature \u7ea7\u522b\u7684\u4e3b\u6210\u5206\u5206\u6790\uff08PCA\uff09\u56fe\uff01\uff01<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 5px 0%;\" powered-by=\"xiumi.us\">\n<section style=\"background-color: rgb(224, 224, 224);height: 1px;\"><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;margin-bottom: 0px;\"><br \/><\/p>\n<p style=\"margin-bottom: 0px;\"><br \/><\/p>\n<p style=\"display: none;\"><mp-style-type data-value=\"3\"><\/mp-style-type><\/p>\n<p><\/content>\n<\/div>\n<p><\/body><br \/>\n<\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u706b\u8fc7\u5f20\u5143\u82f1\u6446\u80ef\uff1f\u8fd9\u5957\u5355\u7ec6\u80de\u5206\u7c7b\u6cd5\u5b9e\u529b\u5f3a\u52b2\uff01\u6e2f\u4e2d\u6587\u674e\u715c\u56e2\u961f9.5\u5206\uff1a\u6df1\u5ea6\u5b66\u4e60+\u81ea\u52a8\u6ce8\u91ca+\u65b0\u578b\u7ec6\u80de\u68c0\u6d4b\uff0c\u7b80\u5355\u65b9\u6cd5\u5e26 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":""},"categories":[1],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/60486"}],"collection":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=60486"}],"version-history":[{"count":1,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/60486\/revisions"}],"predecessor-version":[{"id":60498,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/60486\/revisions\/60498"}],"wp:attachment":[{"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=60486"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=60486"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.biocloudservice.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=60486"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}