{"id":66185,"date":"2026-10-17T00:52:10","date_gmt":"2026-10-16T16:52:10","guid":{"rendered":"https:\/\/www.biocloudservice.com\/wordpress\/?bhr_question=lactylation-single-cell"},"modified":"2026-10-17T00:52:10","modified_gmt":"2026-10-16T16:52:10","slug":"lactylation-single-cell","status":"publish","type":"bhr_question","link":"https:\/\/www.biocloudservice.com\/wordpress\/lactylation\/questions\/lactylation-single-cell\/","title":{"rendered":"\u5355\u7ec6\u80de\u91cc\u600e\u6837\u8bc4\u4f30\u4e73\u9178\u4ee3\u8c22\u4e0e\u4e73\u9178\u5316\u76f8\u5173\u72b6\u6001\uff1f"},"content":{"rendered":"<p><strong>\u76f4\u63a5\u5224\u65ad\uff1a<\/strong>\u5355\u7ec6\u80de RNA \u6d4b\u5e8f\u53ea\u80fd\u63d0\u4f9b\u8f6c\u5f55\u5c42\u9762\u7684\u4ee3\u8c22\u548c\u8c03\u63a7\u7ebf\u7d22\u3002\u5e94\u6309\u7ec6\u80de\u7c7b\u578b\u4e0e\u4f9b\u4f53\u5206\u5c42\uff0c\u5e76\u907f\u514d\u628a\u4e73\u9178\u5316\u5206\u6570\u5f53\u4f5c\u76f4\u63a5\u4fee\u9970\u6d4b\u91cf\u3002<\/p>\n<h2>\u9002\u7528\u6761\u4ef6<\/h2>\n<p>\u5df2\u6709 scRNA-seq \u6570\u636e\uff0c\u60f3\u5b9a\u4f4d\u4e73\u9178\u5316\u76f8\u5173\u7ec6\u80de\u72b6\u6001\u3002<\/p>\n<h2>\u5efa\u8bae\u6309\u8fd9\u4e2a\u987a\u5e8f\u68c0\u67e5<\/h2>\n<ol>\n<li>\u5148\u68c0\u67e5\u4e73\u9178\u4ee3\u8c22\u548c\u8f6c\u8fd0\u57fa\u56e0\u7684\u68c0\u6d4b\u7387\u3002<\/li>\n<li>\u4f7f\u7528\u9884\u5b9a\u4e49\u4e14\u5206\u5c42\u7684\u57fa\u56e0\u96c6\u505a UCell \u7b49\u6392\u5e8f\u578b\u8bc4\u5206\u3002<\/li>\n<li>\u5728\u7ec6\u80de\u7c7b\u578b\u5185\u6bd4\u8f83\uff0c\u5e76\u4ee5\u4f9b\u4f53\u4f5c\u4e3a\u63a8\u65ad\u5355\u4f4d\u3002<\/li>\n<li>\u7ed3\u5408\u7ec4\u7ec7\u6765\u6e90\u3001\u7f3a\u6c27\u3001\u7cd6\u9175\u89e3\u548c\u514d\u75ab\u72b6\u6001\u89e3\u91ca\u3002<\/li>\n<\/ol>\n<h2>\u5df2\u77e5\u9650\u5236<\/h2>\n<p>\u6389\u96f6\u3001\u6d4b\u5e8f\u6df1\u5ea6\u548c\u7ec6\u80de\u7ec4\u6210\u4f1a\u663e\u8457\u5f71\u54cd\u5206\u6570\uff1b\u4e0d\u80fd\u7531\u5355\u7ec6\u80de\u8868\u8fbe\u76f4\u63a5\u5b9a\u4f4d\u4fee\u9970\u4f4d\u70b9\u3002<\/p>\n<h2>\u4f9d\u636e\u4e0e\u7248\u672c<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.bioconductor.org\/packages\/release\/bioc\/html\/UCell.html\" target=\"_blank\" rel=\"noopener noreferrer\">Bioconductor UCell<\/a>\uff08Bioconductor release\uff09<\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41586-019-1678-1\" target=\"_blank\" rel=\"noopener noreferrer\">\u4e73\u9178\u5316\u539f\u59cb\u7814\u7a76\uff1aMetabolic regulation of gene expression by histone lactylation<\/a>\uff08Nature 2019\uff09<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u5355\u7ec6\u80de RNA \u6d4b\u5e8f\u53ea\u80fd\u63d0\u4f9b\u8f6c\u5f55\u5c42\u9762\u7684\u4ee3\u8c22\u548c\u8c03\u63a7\u7ebf\u7d22\u3002\u5e94\u6309\u7ec6\u80de\u7c7b\u578b\u4e0e\u4f9b\u4f53\u5206\u5c42\uff0c\u5e76\u907f\u514d\u628a\u4e73\u9178\u5316\u5206\u6570\u5f53\u4f5c\u76f4\u63a5\u4fee\u9970\u6d4b\u91cf\u3002<\/p>\n","protected":false},"template":"","class_list":["post-66185","bhr_question","type-bhr_question","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/bhr_question\/66185","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/bhr_question"}],"about":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/types\/bhr_question"}],"version-history":[{"count":0,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/bhr_question\/66185\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/media?parent=66185"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}