{"id":65784,"date":"2026-10-10T11:06:52","date_gmt":"2026-10-10T03:06:52","guid":{"rendered":"https:\/\/www.biocloudservice.com\/wordpress\/ferroptosis\/questions\/seurat-addmodulescore-ucell-aucell\/"},"modified":"2026-10-10T11:06:52","modified_gmt":"2026-10-10T03:06:52","slug":"seurat-addmodulescore-ucell-aucell","status":"publish","type":"ftc_question","link":"https:\/\/www.biocloudservice.com\/wordpress\/ferroptosis\/questions\/seurat-addmodulescore-ucell-aucell\/","title":{"rendered":"Seurat \u91cc\u8be5\u7528 AddModuleScore\u3001UCell \u8fd8\u662f AUCell \u505a\u94c1\u6b7b\u4ea1\u8bc4\u5206\uff1f"},"content":{"rendered":"<p class=\"ftc-answer-first\"><strong>\u5148\u770b\u7ed3\u8bba\uff1a<\/strong>\u4e09\u79cd\u65b9\u6cd5\u56de\u7b54\u7684\u662f\u76f8\u8fd1\u4f46\u4e0d\u5b8c\u5168\u76f8\u540c\u7684\u95ee\u9898\u3002AddModuleScore \u4f7f\u7528\u5339\u914d\u8868\u8fbe\u6c34\u5e73\u7684\u5bf9\u7167\u57fa\u56e0\u6821\u6b63\uff1bUCell \u548c AUCell \u57fa\u4e8e\u7ec6\u80de\u5185\u57fa\u56e0\u6392\u5e8f\uff0c\u66f4\u9002\u5408\u5173\u6ce8\u7b7e\u540d\u5728\u5355\u7ec6\u80de\u4e2d\u7684\u76f8\u5bf9\u6d3b\u6027\u3002\u9009\u62e9\u524d\u8981\u5148\u660e\u786e\u6bd4\u8f83\u5355\u4f4d\u548c\u57fa\u56e0\u96c6\u5927\u5c0f\u3002<\/p>\n<h2>\u9002\u7528\u60c5\u51b5<\/h2>\n<p>\u5df2\u7ecf\u5b8c\u6210\u57fa\u672c\u8d28\u63a7\u548c\u8868\u8fbe\u5f52\u4e00\u5316\u7684\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u6570\u636e\uff0c\u51c6\u5907\u5728\u7ec6\u80de\u6216\u7ec6\u80de\u7c7b\u578b\u5c42\u9762\u8bc4\u4f30\u94c1\u6b7b\u4ea1\u76f8\u5173\u7b7e\u540d\u3002<\/p>\n<h2>\u5efa\u8bae\u6309\u8fd9\u4e2a\u987a\u5e8f\u68c0\u67e5<\/h2>\n<ol>\n<li>\u68c0\u67e5\u94c1\u6b7b\u4ea1\u57fa\u56e0\u5728\u5bf9\u8c61\u4e2d\u7684\u547d\u4e2d\u7387\u3001\u7269\u79cd\u7b26\u53f7\u548c\u540c\u4e49\u540d\uff0c\u4e0d\u80fd\u5ffd\u7565\u5927\u91cf\u672a\u547d\u4e2d\u57fa\u56e0\u3002<\/li>\n<li>\u4f7f\u7528 AddModuleScore \u65f6\u8bb0\u5f55 assay\u3001layer\/slot\u3001nbin\u3001ctrl \u548c\u968f\u673a\u79cd\u5b50\uff0c\u5e76\u786e\u8ba4\u5bf9\u7167\u57fa\u56e0\u6c60\u662f\u5426\u5408\u7406\u3002<\/li>\n<li>\u5982\u679c\u6570\u636e\u96c6\u5927\u5c0f\u548c\u7ec6\u80de\u7ec4\u6210\u5dee\u5f02\u8f83\u5927\uff0c\u53ef\u4f18\u5148\u8003\u8651\u57fa\u4e8e\u6392\u5e8f\u7684 UCell\uff0c\u5e76\u628a\u5176\u4ed6\u65b9\u6cd5\u4f5c\u4e3a\u654f\u611f\u6027\u5206\u6790\u3002<\/li>\n<li>AUCell \u66f4\u9002\u5408\u5224\u65ad\u67d0\u4e2a\u7b7e\u540d\u662f\u5426\u96c6\u4e2d\u51fa\u73b0\u5728\u7ec6\u80de\u6392\u5e8f\u524d\u90e8\uff1b\u9608\u503c\u4e0d\u80fd\u672a\u7ecf\u68c0\u67e5\u76f4\u63a5\u8de8\u6570\u636e\u96c6\u590d\u7528\u3002<\/li>\n<li>\u7ec4\u95f4\u63a8\u65ad\u5e94\u4ee5\u4f9b\u4f53\u6216\u751f\u7269\u5b66\u6837\u672c\u4e3a\u91cd\u590d\u5355\u4f4d\uff0c\u4e0d\u80fd\u628a\u51e0\u4e07\u4e2a\u7ec6\u80de\u5f53\u6210\u51e0\u4e07\u4e2a\u72ec\u7acb\u6837\u672c\u3002<\/li>\n<\/ol>\n<h2>\u4e0d\u80fd\u4ece\u5f53\u524d\u7ed3\u679c\u76f4\u63a5\u5f97\u51fa\u4ec0\u4e48<\/h2>\n<p>\u4efb\u4f55\u5355\u7ec6\u80de\u7b7e\u540d\u5206\u6570\u90fd\u53d7\u57fa\u56e0\u96c6\u3001\u6d4b\u5e8f\u6df1\u5ea6\u3001\u7ec6\u80de\u7c7b\u578b\u548c\u9884\u5904\u7406\u5f71\u54cd\u3002\u5206\u6570\u5347\u9ad8\u53ea\u80fd\u652f\u6301\u8f6c\u5f55\u5c42\u9762\u7684\u76f8\u5173\u6a21\u5f0f\uff0c\u4e0d\u80fd\u5355\u72ec\u8bc1\u660e\u53d1\u751f\u94c1\u6b7b\u4ea1\u3002<\/p>\n<h2>\u4f9d\u636e\u4e0e\u7248\u672c<\/h2>\n<ul class=\"ftc-source-list\">\n<li><a href=\"https:\/\/satijalab.org\/seurat\/reference\/addmodulescore\" target=\"_blank\" rel=\"noopener noreferrer\">Seurat AddModuleScore \u5b98\u65b9\u6587\u6863<\/a><span>Seurat \u5f53\u524d\u6587\u6863<\/span><\/li>\n<li><a href=\"https:\/\/www.bioconductor.org\/packages\/release\/bioc\/html\/UCell.html\" target=\"_blank\" rel=\"noopener noreferrer\">Bioconductor UCell<\/a><span>UCell release<\/span><\/li>\n<li><a href=\"https:\/\/bioconductor.org\/packages\/release\/bioc\/vignettes\/AUCell\/inst\/doc\/AUCell.html\" target=\"_blank\" rel=\"noopener noreferrer\">Bioconductor AUCell \u4f7f\u7528\u8bf4\u660e<\/a><span>AUCell release<\/span><\/li>\n<\/ul>\n<p class=\"ftc-verification\">\u6700\u540e\u6838\u9a8c\uff1a2026-10-10\uff5c\u8d44\u6599\u6838\u9a8c\uff1a\u516c\u5f00\u6765\u6e90\u6838\u5bf9<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4e09\u79cd\u65b9\u6cd5\u56de\u7b54\u7684\u662f\u76f8\u8fd1\u4f46\u4e0d\u5b8c\u5168\u76f8\u540c\u7684\u95ee\u9898\u3002AddModuleScore \u4f7f\u7528\u5339\u914d\u8868\u8fbe\u6c34\u5e73\u7684\u5bf9\u7167\u57fa\u56e0\u6821\u6b63\uff1bUCell \u548c AUCell \u57fa\u4e8e\u7ec6\u80de\u5185\u57fa\u56e0\u6392\u5e8f\uff0c\u66f4\u9002\u5408\u5173\u6ce8\u7b7e\u540d\u5728\u5355\u7ec6\u80de\u4e2d\u7684\u76f8\u5bf9\u6d3b\u6027\u3002\u9009\u62e9\u524d\u8981\u5148\u660e\u786e\u6bd4\u8f83\u5355\u4f4d\u548c\u57fa\u56e0\u96c6\u5927\u5c0f\u3002<\/p>\n","protected":false},"template":"","class_list":["post-65784","ftc_question","type-ftc_question","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/ftc_question\/65784","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/ftc_question"}],"about":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/types\/ftc_question"}],"version-history":[{"count":0,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/ftc_question\/65784\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/media?parent=65784"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}