{"id":65842,"date":"2026-10-10T14:00:37","date_gmt":"2026-10-10T06:00:37","guid":{"rendered":"https:\/\/www.biocloudservice.com\/wordpress\/?post_type=ftc_question&p=65842"},"modified":"2026-10-10T14:00:37","modified_gmt":"2026-10-10T06:00:37","slug":"find-geo-ferroptosis-disease-datasets","status":"publish","type":"ftc_question","link":"https:\/\/www.biocloudservice.com\/wordpress\/ferroptosis\/questions\/find-geo-ferroptosis-disease-datasets\/","title":{"rendered":"\u600e\u6837\u67e5\u627e\u9002\u5408\u67d0\u75be\u75c5\u7684 GEO \u94c1\u6b7b\u4ea1\u6570\u636e\uff1f"},"content":{"rendered":"

\u5148\u770b\u7ed3\u8bba\uff1a<\/strong>\u5148\u6309\u75be\u75c5\u3001\u7ec4\u7ec7\u3001\u7269\u79cd\u548c\u6bd4\u8f83\u8bbe\u8ba1\u627e\u6570\u636e\uff0c\u518d\u5224\u65ad\u662f\u5426\u9002\u5408\u94c1\u6b7b\u4ea1\u95ee\u9898\u3002\u4ec5\u641c\u7d22\u201c\u75be\u75c5\u540d + ferroptosis\u201d\u4f1a\u6f0f\u6389\u6ca1\u6709\u5728\u6807\u9898\u4e2d\u5199\u94c1\u6b7b\u4ea1\u3001\u4f46\u5305\u542b\u53ef\u7528\u8868\u8fbe\u548c\u5206\u7ec4\u7684\u6570\u636e\u3002\u53ef\u7528\u6027\u53d6\u51b3\u4e8e\u6837\u672c\u8bbe\u8ba1\u3001\u6587\u4ef6\u548c\u5143\u6570\u636e\uff0c\u800c\u4e0d\u662f\u641c\u7d22\u7ed3\u679c\u6570\u91cf\u3002<\/p>\n

\u9002\u7528\u60c5\u51b5<\/h2>\n

\u5c1a\u672a\u786e\u5b9a\u5206\u6790\u961f\u5217\uff0c\u5e0c\u671b\u627e\u5230\u75be\u75c5\u76f8\u5173\u7684\u82af\u7247\u3001bulk RNA-seq \u6216\u5355\u7ec6\u80de\u516c\u5f00\u6570\u636e\u3002<\/p>\n

\u5efa\u8bae\u6309\u8fd9\u4e2a\u987a\u5e8f\u68c0\u67e5<\/h2>\n
    \n
  1. \u628a\u79d1\u5b66\u95ee\u9898\u5199\u6210\u7814\u7a76\u5bf9\u8c61\u3001\u6bd4\u8f83\u7ec4\u3001\u7ec4\u7ec7\u3001\u7269\u79cd\u548c\u7ed3\u5c40\u4e94\u9879\uff0c\u5148\u786e\u5b9a\u54ea\u4e9b\u6761\u4ef6\u4e0d\u53ef\u59a5\u534f\u3002<\/li>\n
  2. \u5728 GEO DataSets \u7528\u75be\u75c5\u540c\u4e49\u8bcd\u68c0\u7d22\uff0c\u7ed3\u5408\u7269\u79cd\u4e0e\u5b9e\u9a8c\u7c7b\u578b\u7b5b\u9009\uff1b\u673a\u5236\u8bcd\u4f5c\u4e3a\u6269\u5c55\u6761\u4ef6\u3002<\/li>\n
  3. \u8fdb\u5165\u5019\u9009 GSE\uff0c\u68c0\u67e5\u6574\u4f53\u8bbe\u8ba1\u3001\u5404 GSM\u3001\u5e73\u53f0 GPL\u3001\u8865\u5145\u6587\u4ef6\u548c\u5173\u8054\u8bba\u6587\uff0c\u5efa\u7acb\u6837\u672c\u6e05\u5355\u3002<\/li>\n
  4. \u786e\u8ba4\u53ef\u83b7\u5f97\u539f\u59cb\u6216\u5904\u7406\u540e\u8868\u8fbe\uff0c\u660e\u786e\u5355\u4f4d\u3001\u4f9b\u4f53\u3001\u5206\u7ec4\u548c\u914d\u5bf9\u5173\u7cfb\uff0c\u4e0d\u80fd\u53ea\u6839\u636e\u6807\u9898\u9009\u4e2d\u3002<\/li>\n
  5. \u628a\u6bcf\u4e2a\u961f\u5217\u6807\u4e3a\u53ef\u5206\u6790\u3001\u9700\u8865\u4fe1\u606f\u6216\u6392\u9664\u5e76\u8bb0\u5f55\u7406\u7531\uff0c\u518d\u89c4\u5212\u8bad\u7ec3\u4e0e\u72ec\u7acb\u9a8c\u8bc1\u7684\u7528\u9014\u3002<\/li>\n<\/ol>\n

    \u4e00\u4e2a\u53ef\u8c03\u6574\u7684\u68c0\u7d22\u8d77\u70b9<\/h2>\n

    \u4ee5\u4e0a\u662f\u80c3\u764c\u4eba\u7c7b\u6570\u636e\u7684\u68c0\u7d22\u8868\u8fbe\u5f0f\u793a\u4f8b\uff0c\u4e0d\u662f\u4fdd\u8bc1\u6709\u7279\u5b9a\u6570\u91cf\u7ed3\u679c\u7684\u56fa\u5b9a\u68c0\u7d22\u7b56\u7565\u3002\u53ef\u5728 GEO \u7684\u7b5b\u9009\u9879\u7ee7\u7eed\u9009\u62e9\u8868\u8fbe\u82af\u7247\u6216\u9ad8\u901a\u91cf\u6d4b\u5e8f\uff1b\u9700\u8981\u5355\u7ec6\u80de\u65f6\u52a0\u5165 single cell\u3001scRNA-seq \u7b49\u5173\u952e\u8bcd\u5e76\u9010\u6761\u786e\u8ba4\u3002<\/p>\n

    \u7b2c\u4e8c\u8f6e\u518d\u589e\u52a0 ferroptosis \u6216\u5177\u4f53\u5e72\u9884\u8bcd\uff0c\u53ef\u5bfb\u627e\u5df2\u56f4\u7ed5\u8be5\u673a\u5236\u8bbe\u8ba1\u7684\u7814\u7a76\u3002\u4e24\u4e2a\u68c0\u7d22\u65b9\u5411\u7684\u76ee\u7684\u4e0d\u540c\uff1a\u524d\u8005\u627e\u53ef\u91cd\u65b0\u5206\u6790\u7684\u75be\u75c5\u961f\u5217\uff0c\u540e\u8005\u627e\u66f4\u76f4\u63a5\u7684\u673a\u5236\u6216\u5e72\u9884\u8d44\u6599\u3002<\/p>\n

    ("gastric cancer" OR "gastric carcinoma") AND "Homo sapiens"[Organism]<\/code><\/pre>\n
    \u4f9d\u636e\uff1aNCBI GEO\uff1a\u68c0\u7d22\u4e0e\u8bb0\u5f55\u5165\u53e3<\/a><\/p>\n
    \u5019\u9009\u6570\u636e\u9a8c\u6536\u8868<\/h2>\n
    \n\n\n\n\n\n\n\n\n\n
    \u6838\u5bf9\u9879<\/th>\n\u5fc5\u987b\u5199\u6e05<\/th>\n\u4e0d\u6ee1\u8db3\u65f6<\/th>\n<\/tr>\n<\/thead>\n
    \u7814\u7a76\u6bd4\u8f83<\/td>\n\u75c5\u4f8b\/\u5bf9\u7167\u3001\u6cbb\u7597\u524d\u540e\u6216\u5176\u4ed6\u5177\u4f53\u6bd4\u8f83<\/td>\n\u6539\u95ee\u9898\u6216\u6392\u9664<\/td>\n<\/tr>\n
    \u72ec\u7acb\u91cd\u590d<\/td>\n\u4f9b\u4f53\u6570\u4e0e\u6bcf\u4e2a\u4f9b\u4f53\u6837\u672c\u5173\u7cfb<\/td>\n\u4e0d\u4ee5 run \u6216\u7ec6\u80de\u6570\u66ff\u4ee3<\/td>\n<\/tr>\n
    \u8f93\u5165\u6587\u4ef6<\/td>\n\u6587\u4ef6\u540d\u3001\u5355\u4f4d\u3001\u5e73\u53f0\u548c\u53ef\u4e0b\u8f7d\u72b6\u6001<\/td>\n\u8bb0\u5f55\u7f3a\u5931\u5e76\u5bfb\u627e\u66ff\u4ee3\u6570\u636e<\/td>\n<\/tr>\n
    \u6f5c\u5728\u6df7\u6742<\/td>\n\u6279\u6b21\u3001\u7ec4\u7ec7\u6765\u6e90\u3001\u5904\u7406\u548c\u914d\u5bf9<\/td>\n\u8bc4\u4f30\u662f\u5426\u53ef\u8c03\u6574<\/td>\n<\/tr>\n
    \u72ec\u7acb\u6027<\/td>\n\u4e0e\u5176\u4ed6\u961f\u5217\u662f\u5426\u5171\u4eab\u6837\u672c<\/td>\n\u4e0d\u80fd\u91cd\u590d\u8ba1\u7b97\u5916\u90e8\u9a8c\u8bc1<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
    \u4e00\u4e2a\u771f\u5b9e\u7684\u6570\u636e\u7c7b\u578b\u63d0\u9192<\/h2>\n
    GSE13195 \u5728 GEO \u767b\u8bb0\u7684\u5e73\u53f0\u4e3a GPL5175\uff0c\u5c5e\u4e8e Affymetrix Human Exon 1.0 ST \u8868\u8fbe\u82af\u7247\u3002\u8fd9\u4e2a\u53ef\u6838\u5bf9\u7684\u4e8b\u5b9e\u53ea\u56de\u7b54\u8f93\u5165\u7c7b\u578b\uff0c\u4e0d\u80fd\u987a\u5e26\u8bc1\u660e\u5b83\u9002\u5408\u4f60\u5f53\u524d\u7684\u6bd4\u8f83\u8bbe\u8ba1\u3002\u4ecd\u9700\u9010 GSM \u6838\u5b9e\u7eb3\u5165\u89c4\u5219\u548c\u6837\u672c\u5173\u7cfb\u3002<\/p>\n
    \u672c\u9875\u672a\u5bf9\u8be5\u961f\u5217\u91cd\u8dd1\u5dee\u5f02\u5206\u6790\uff0c\u4e5f\u4e0d\u63d0\u4f9b\u201c\u5df2\u7b5b\u597d\u201d\u7684\u4e34\u5e8a\u5206\u7ec4\u3002\u62ff\u5230\u5019\u9009\u5217\u8868\u540e\uff0c\u6700\u6709\u4ef7\u503c\u7684\u4e00\u6b65\u662f\u5148\u5b8c\u6210\u6837\u672c\u548c\u6587\u4ef6\u6838\u67e5\uff0c\u518d\u6295\u5165\u6279\u91cf\u8ba1\u7b97\u3002<\/p>\n
    \u4f9d\u636e\uff1aNCBI GEO\uff1aGSE13195 \u539f\u59cb\u767b\u8bb0\u8bb0\u5f55<\/a><\/p>\n
    \u4e0d\u80fd\u4ece\u5f53\u524d\u7ed3\u679c\u76f4\u63a5\u5f97\u51fa\u4ec0\u4e48<\/h2>\n
    \u516c\u5f00\u53ef\u4e0b\u8f7d\u4e0d\u7b49\u4e8e\u9002\u7528\u4e8e\u5f53\u524d\u8bfe\u9898\u3002\u641c\u7d22\u547d\u4e2d\u6570\u3001\u6570\u636e\u6807\u9898\u548c\u5173\u8054\u8bba\u6587\u4e2d\u7684\u663e\u8457\u7ed3\u679c\u90fd\u4e0d\u80fd\u66ff\u4ee3\u5143\u6570\u636e\u6838\u67e5\uff1b\u7f3a\u5931\u4e34\u5e8a\u5b57\u6bb5\u4e5f\u4e0d\u80fd\u7531\u6a21\u578b\u731c\u6d4b\u586b\u5165\u3002<\/p>\n
    \u4f9d\u636e\u4e0e\u7248\u672c<\/h2>\n