{"id":65849,"date":"2026-10-10T14:00:37","date_gmt":"2026-10-10T06:00:37","guid":{"rendered":"https:\/\/www.biocloudservice.com\/wordpress\/?post_type=ftc_question&#038;p=65849"},"modified":"2026-10-10T14:00:37","modified_gmt":"2026-10-10T06:00:37","slug":"prognosis-diagnosis-or-mechanism-study","status":"publish","type":"ftc_question","link":"https:\/\/www.biocloudservice.com\/wordpress\/ferroptosis\/questions\/prognosis-diagnosis-or-mechanism-study\/","title":{"rendered":"\u5e94\u8be5\u505a\u9884\u540e\u6a21\u578b\u3001\u8bca\u65ad\u6a21\u578b\uff0c\u8fd8\u662f\u673a\u5236\u9a8c\u8bc1\uff1f"},"content":{"rendered":"<p class=\"ftc-answer-first\"><strong>\u5148\u770b\u7ed3\u8bba\uff1a<\/strong>\u9009\u62e9\u53d6\u51b3\u4e8e\u60f3\u89e3\u51b3\u7684\u95ee\u9898\u548c\u73b0\u6709\u6570\u636e\u3002\u9884\u540e\u6a21\u578b\u9700\u8981\u660e\u786e\u7684\u672a\u6765\u7ed3\u5c40\u3001\u65f6\u95f4\u548c\u968f\u8bbf\u4fe1\u606f\uff1b\u8bca\u65ad\u6a21\u578b\u5173\u6ce8\u5f53\u524d\u72b6\u6001\u7684\u8bc6\u522b\uff0c\u9700\u8981\u53ef\u9760\u53c2\u8003\u6807\u51c6\u548c\u5408\u9002\u7684\u4eba\u7fa4\uff1b\u673a\u5236\u7814\u7a76\u5173\u6ce8\u5e72\u9884\u662f\u5426\u6539\u53d8\u8fc7\u7a0b\u53ca\u7ed3\u679c\u3002\u5148\u9009\u76ee\u6807\uff0c\u518d\u51b3\u5b9a\u5206\u6790\uff0c\u800c\u4e0d\u662f\u5148\u5957\u6a21\u677f\u518d\u5bfb\u627e\u7ed3\u8bba\u3002<\/p>\n<h2>\u9002\u7528\u60c5\u51b5<\/h2>\n<p>\u62e5\u6709\u8868\u8fbe\u77e9\u9635\u53ca\u90e8\u5206\u4e34\u5e8a\u4fe1\u606f\uff0c\u6b63\u5728\u51b3\u5b9a\u8d70\u9884\u6d4b\u5efa\u6a21\u3001\u75be\u75c5\u533a\u5206\u8fd8\u662f\u5019\u9009\u673a\u5236\u9a8c\u8bc1\u8def\u7ebf\u3002<\/p>\n<h2>\u5efa\u8bae\u6309\u8fd9\u4e2a\u987a\u5e8f\u68c0\u67e5<\/h2>\n<ol>\n<li>\u7528\u4e00\u53e5\u8bdd\u5199\u51fa\u76ee\u6807\u3001\u5bf9\u8c61\u548c\u4f7f\u7528\u573a\u666f\uff1a\u9884\u6d4b\u4ec0\u4e48\u3001\u4f55\u65f6\u9884\u6d4b\u3001\u5bf9\u8c01\u6709\u610f\u4e49\u3002<\/li>\n<li>\u76d8\u70b9\u7ed3\u5c40\u3001\u65f6\u95f4\u3001\u5220\u5931\u3001\u6807\u7b7e\u6765\u6e90\u548c\u53ef\u7528\u9884\u6d4b\u53d8\u91cf\uff0c\u786e\u8ba4\u53d8\u91cf\u5728\u9884\u5b9a\u9884\u6d4b\u65f6\u70b9\u5df2\u7ecf\u53ef\u83b7\u5f97\u3002<\/li>\n<li>\u9884\u6d4b\u7814\u7a76\u5148\u89c4\u5b9a\u5f00\u53d1\u548c\u9a8c\u8bc1\u65b9\u6848\u3001\u7f3a\u5931\u5904\u7406\u3001\u7279\u5f81\u7b5b\u9009\u4e0e\u6027\u80fd\u6307\u6807\uff0c\u8bc4\u4f30\u4e8b\u4ef6\u6570\u91cf\u548c\u590d\u6742\u5ea6\u662f\u5426\u5339\u914d\u3002<\/li>\n<li>\u673a\u5236\u7814\u7a76\u5219\u56f4\u7ed5\u5019\u9009\u7684\u53ef\u5e72\u9884\u6027\u3001\u8868\u578b\u548c\u66ff\u4ee3\u89e3\u91ca\u8bbe\u8ba1\uff0c\u4e0d\u4ee5\u9ad8 AUC \u66ff\u4ee3\u673a\u5236\u8bc1\u636e\u3002<\/li>\n<li>\u82e5\u6838\u5fc3\u6570\u636e\u7f3a\u5931\uff0c\u7f29\u5c0f\u4e3a\u63a2\u7d22\u6027\u5173\u8054\u6216\u8865\u5145\u6570\u636e\uff0c\u5e76\u660e\u786e\u5f53\u524d\u9636\u6bb5\u4e0d\u80fd\u5b8c\u6210\u7684\u76ee\u6807\u3002<\/li>\n<\/ol>\n<h2>\u4e09\u6761\u8def\u7ebf\u7684\u8f93\u5165\u548c\u4ea4\u4ed8\u4e0d\u540c<\/h2>\n<div class=\"ftc-table-wrap\" role=\"region\" tabindex=\"0\" aria-label=\"\u4e09\u6761\u8def\u7ebf\u7684\u8f93\u5165\u548c\u4ea4\u4ed8\u4e0d\u540c\">\n<table>\n<thead>\n<tr>\n<th scope=\"col\">\u8def\u7ebf<\/th>\n<th scope=\"col\">\u6700\u4f4e\u9700\u8981\u6838\u5bf9<\/th>\n<th scope=\"col\">\u4e3b\u8981\u7ed3\u679c\u4e0e\u9650\u5236<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u9884\u540e\u9884\u6d4b<\/td>\n<td>\u8d77\u59cb\u65f6\u70b9\u3001\u7ed3\u5c40\u5b9a\u4e49\u3001\u968f\u8bbf\u65f6\u95f4\u3001\u5220\u5931<\/td>\n<td>\u9002\u5f53\u65f6\u95f4\u8303\u56f4\u7684\u533a\u5206\u5ea6\u4e0e\u6821\u51c6\uff1b\u4e0d\u80fd\u53ea\u7ed9\u751f\u5b58\u66f2\u7ebf<\/td>\n<\/tr>\n<tr>\n<td>\u8bca\u65ad\u9884\u6d4b<\/td>\n<td>\u76ee\u6807\u4eba\u7fa4\u3001\u5f53\u524d\u72b6\u6001\u7684\u53c2\u8003\u6807\u51c6\u3001\u91c7\u6837\u65b9\u5f0f<\/td>\n<td>\u533a\u5206\u5ea6\u3001\u6821\u51c6\u53ca\u9608\u503c\u8868\u73b0\uff1b\u75c5\u4f8b\u5bf9\u7167\u7ed3\u679c\u672a\u5fc5\u9002\u7528\u4e8e\u7b5b\u67e5<\/td>\n<\/tr>\n<tr>\n<td>\u673a\u5236\u9a8c\u8bc1<\/td>\n<td>\u5e72\u9884\u6761\u4ef6\u3001\u76ee\u6807\u8bfb\u6570\u3001\u6070\u5f53\u5bf9\u7167<\/td>\n<td>\u529f\u80fd\u4f9d\u8d56\u548c\u53ef\u91cd\u590d\u6027\uff1b\u76f8\u5173\u6027\u4e0d\u80fd\u66ff\u4ee3\u5e72\u9884<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p class=\"ftc-inline-sources\">\u4f9d\u636e\uff1a<a href=\"https:\/\/www.tripod-statement.org\/resources\/\" target=\"_blank\" rel=\"noopener noreferrer\">TRIPOD \u5b98\u65b9\u8d44\u6e90\uff1a\u9884\u6d4b\u6a21\u578b\u5f00\u53d1\u4e0e\u9a8c\u8bc1\u6e05\u5355<\/a> \u00b7 <a href=\"https:\/\/www.nature.com\/articles\/s41418-017-0012-4\" target=\"_blank\" rel=\"noopener noreferrer\">NCCD\uff1a\u7ec6\u80de\u6b7b\u4ea1\u7684\u673a\u5236\u5b9a\u4e49\u4e0e\u8bc1\u636e\u89e3\u91ca<\/a><\/p>\n<h2>\u4e24\u4e2a\u5e38\u89c1\u7684\u76ee\u6807\u9519\u914d<\/h2>\n<p>\u793a\u610f\u60c5\u5883\u4e00\uff1a\u53ea\u6709\u80bf\u7624\u4e0e\u90bb\u8fd1\u7ec4\u7ec7\u8868\u8fbe\uff0c\u6ca1\u6709\u968f\u8bbf\u3002\u53ef\u4ee5\u8bc4\u4f30\u8868\u8fbe\u5dee\u5f02\u6216\u63a2\u7d22\u6837\u672c\u533a\u5206\uff0c\u4f46\u4e0d\u80fd\u51ed\u7a7a\u6784\u5efa\u53ef\u4fe1\u7684\u751f\u5b58\u9884\u540e\u76ee\u6807\uff1b\u90bb\u8fd1\u7ec4\u7ec7\u4e0e\u5065\u5eb7\u7b5b\u67e5\u4eba\u7fa4\u4e5f\u4e0d\u662f\u540c\u4e00\u79cd\u5bf9\u7167\u3002<\/p>\n<p>\u793a\u610f\u60c5\u5883\u4e8c\uff1a\u4e00\u4e2a\u57fa\u56e0\u80fd\u5f88\u597d\u5730\u533a\u5206\u4e24\u7ec4\uff0c\u4f46\u5e72\u9884\u540e\u5e76\u6ca1\u6709\u51fa\u73b0\u9884\u671f\u529f\u80fd\u53d8\u5316\u3002\u9884\u6d4b\u5173\u8054\u548c\u673a\u5236\u4f5c\u7528\u56de\u7b54\u4e0d\u540c\u95ee\u9898\uff0c\u8fd9\u4e0d\u662f\u7b80\u5355\u7684\u201c\u6a21\u578b\u8bc1\u660e\u4e86\u673a\u5236\u3001\u5b9e\u9a8c\u5374\u5931\u8d25\u201d\u3002\u5e94\u5206\u522b\u5ba1\u67e5\u7279\u5f81\u662f\u5426\u6355\u6349\u4e86\u6df7\u6742\uff0c\u4ee5\u53ca\u5b9e\u9a8c\u662f\u5426\u68c0\u9a8c\u4e86\u539f\u5047\u8bbe\u3002<\/p>\n<h2>\u7acb\u9879\u524d\u5199\u4e0b\u8fd9\u4e94\u53e5\u8bdd<\/h2>\n<p>\u2460 \u672c\u7814\u7a76\u9488\u5bf9\u7684\u5bf9\u8c61\u4e0e\u4f7f\u7528\u573a\u666f\u3002\u2461 \u4e3b\u8981\u7ed3\u5c40\u6216\u673a\u5236\u5047\u8bbe\u3002\u2462 \u73b0\u6709\u6570\u636e\u4e2d\u54ea\u4e9b\u5b57\u6bb5\u652f\u6301\u5b83\u3002\u2463 \u5982\u4f55\u5728\u672a\u53c2\u4e0e\u5f00\u53d1\u7684\u6750\u6599\u4e0a\u9a8c\u8bc1\u3002\u2464 \u4ec0\u4e48\u7ed3\u679c\u4f1a\u8ba9\u6211\u4eec\u5426\u5b9a\u6216\u8c03\u6574\u5047\u8bbe\u3002<\/p>\n<p>\u5982\u679c\u8fd9\u4e94\u53e5\u8bdd\u65e0\u6cd5\u586b\u5b9e\uff0c\u5148\u5b8c\u6210\u6570\u636e\u6838\u67e5\u5f80\u5f80\u6bd4\u540c\u65f6\u505a\u9884\u540e\u3001\u8bca\u65ad\u548c\u673a\u5236\u4e09\u6761\u7ebf\u66f4\u6709\u6548\u3002\u9884\u6d4b\u6a21\u578b\u62a5\u544a\u53ef\u4f9d\u636e TRIPOD+AI\uff1b\u5b83\u66f4\u65b0\u5e76\u66ff\u4ee3 TRIPOD 2015\uff0c\u9002\u7528\u4e8e\u56de\u5f52\u4e0e\u673a\u5668\u5b66\u4e60\u65b9\u6cd5\u3002\u5f15\u7528\u5386\u53f2\u6e05\u5355\u65f6\u5e94\u8bf4\u660e\u7248\u672c\uff0c\u5e76\u6309\u7814\u7a76\u7c7b\u578b\u548c\u6295\u7a3f\u8981\u6c42\u6838\u5bf9\u6269\u5c55\u89c4\u8303\u3002<\/p>\n<p class=\"ftc-inline-sources\">\u4f9d\u636e\uff1a<a href=\"https:\/\/www.tripod-statement.org\/scope\/\" target=\"_blank\" rel=\"noopener noreferrer\">TRIPOD+AI \u5b98\u65b9\u9002\u7528\u8303\u56f4\u4e0e\u66f4\u65b0\u8bf4\u660e<\/a><\/p>\n<h2>\u4e0d\u80fd\u4ece\u5f53\u524d\u7ed3\u679c\u76f4\u63a5\u5f97\u51fa\u4ec0\u4e48<\/h2>\n<p>\u516c\u5f00\u961f\u5217\u4e0a\u7684\u6a21\u578b\u8868\u73b0\u4e0d\u80fd\u76f4\u63a5\u8f6c\u5316\u4e3a\u4e34\u5e8a\u8bca\u65ad\u6216\u7528\u836f\u5de5\u5177\u3002\u9ad8 AUC\u3001\u663e\u8457 HR \u6216\u6f02\u4eae\u7684\u5217\u7ebf\u56fe\u90fd\u4e0d\u80fd\u514d\u9664\u72ec\u7acb\u9a8c\u8bc1\u3001\u6821\u51c6\u4e0e\u4f7f\u7528\u573a\u666f\u8bc4\u4f30\u3002<\/p>\n<h2>\u4f9d\u636e\u4e0e\u7248\u672c<\/h2>\n<ul class=\"ftc-source-list\">\n<li><a href=\"https:\/\/www.tripod-statement.org\/resources\/\" target=\"_blank\" rel=\"noopener noreferrer\">TRIPOD \u5b98\u65b9\u8d44\u6e90\uff1a\u9884\u6d4b\u6a21\u578b\u5f00\u53d1\u4e0e\u9a8c\u8bc1\u6e05\u5355<\/a><span>2015 \u57fa\u7840\u8d44\u6599\u4e0e\u52d8\u8bef\uff1b\u73b0\u884c\u66f4\u65b0\u53e6\u89c1 TRIPOD+AI<\/span><\/li>\n<li><a href=\"https:\/\/www.tripod-statement.org\/scope\/\" target=\"_blank\" rel=\"noopener noreferrer\">TRIPOD+AI \u5b98\u65b9\u9002\u7528\u8303\u56f4\u4e0e\u66f4\u65b0\u8bf4\u660e<\/a><span>TRIPOD+AI\uff1b\u9002\u7528\u4e8e\u56de\u5f52\u4e0e\u673a\u5668\u5b66\u4e60\u9884\u6d4b\u6a21\u578b<\/span><\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41418-017-0012-4\" target=\"_blank\" rel=\"noopener noreferrer\">NCCD\uff1a\u7ec6\u80de\u6b7b\u4ea1\u7684\u673a\u5236\u5b9a\u4e49\u4e0e\u8bc1\u636e\u89e3\u91ca<\/a><span>Cell Death &amp; Differentiation\uff0c2018\uff1b\u673a\u5236\u5b9a\u4e49\u53c2\u8003<\/span><\/li>\n<li><a href=\"https:\/\/bioconductor.org\/packages\/release\/bioc\/vignettes\/DESeq2\/inst\/doc\/DESeq2.html\" target=\"_blank\" rel=\"noopener noreferrer\">DESeq2 \u5b98\u65b9\u6559\u7a0b\uff1a\u8f93\u5165\u3001\u8bbe\u8ba1\u77e9\u9635\u4e0e\u6280\u672f\u91cd\u590d<\/a><span>release \u5728\u7ebf\u6559\u7a0b\uff1b\u793a\u4f8b\u5e94\u5339\u914d\u672c\u5730\u7248\u672c<\/span><\/li>\n<\/ul>\n<p class=\"ftc-verification\">\u6700\u540e\u6838\u9a8c\uff1a2026-10-10\uff5c\u8d44\u6599\u6838\u9a8c\uff1aAI \u7f16\u5199\u4e0e\u516c\u5f00\u6765\u6e90\u6838\u5bf9\uff1b\u672a\u7ecf\u4eba\u5de5\u4e13\u5bb6\u5ba1\u9605<\/p>\n<p class=\"ftc-verification\">\u4f9d\u636e\u516c\u5f00\u6765\u6e90\u6838\u5bf9\u6982\u5ff5\u3001\u8f93\u5165\u3001\u8bc1\u636e\u8fb9\u754c\u4e0e\u7248\u672c\u53e3\u5f84\uff1b\u793a\u610f\u6570\u636e\u4e0d\u4ee3\u8868\u771f\u5b9e\u7814\u7a76\u7ed3\u679c\u3002\u4ec5\u6807\u660e\u7684\u5c0f\u578b\u4ee3\u7801\u793a\u4f8b\u7ecf\u8fc7\u8fd0\u884c\u68c0\u67e5\uff0c\u4e0d\u4ee3\u8868\u5b8c\u6574\u751f\u7269\u4fe1\u606f\u6d41\u7a0b\u6216\u539f\u8bba\u6587\u5df2\u590d\u73b0\u3002<\/p>\n<h2>\u7ee7\u7eed\u89e3\u51b3\u76f8\u5173\u95ee\u9898<\/h2>\n<ul class=\"ftc-related-reading\">\n<li><a href=\"https:\/\/www.biocloudservice.com\/wordpress\/ferroptosis\/questions\/ferroptosis-model-overfitting-validation\/\">\u7528\u94c1\u6b7b\u4ea1\u57fa\u56e0\u505a WGCNA\u3001\u673a\u5668\u5b66\u4e60\u6216\u9884\u540e\u6a21\u578b\uff0c\u600e\u6837\u907f\u514d\u8fc7\u62df\u5408\uff1f<\/a><\/li>\n<li><a href=\"https:\/\/www.biocloudservice.com\/wordpress\/ferroptosis\/questions\/can-my-data-support-ferroptosis-study\/\">\u6211\u73b0\u6709\u7684\u6570\u636e\u80fd\u4e0d\u80fd\u652f\u6491\u4e00\u4e2a\u94c1\u6b7b\u4ea1\u7814\u7a76\u4e3b\u9898\uff1f<\/a><\/li>\n<li><a href=\"https:\/\/www.biocloudservice.com\/wordpress\/ferroptosis\/questions\/ferroptosis-external-single-cell-experimental-validation\/\">\u94c1\u6b7b\u4ea1\u7ed3\u679c\u81f3\u5c11\u9700\u8981\u54ea\u4e9b\u5916\u90e8\u961f\u5217\u3001\u5355\u7ec6\u80de\u6216\u5b9e\u9a8c\u9a8c\u8bc1\uff1f<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u9009\u62e9\u53d6\u51b3\u4e8e\u60f3\u89e3\u51b3\u7684\u95ee\u9898\u548c\u73b0\u6709\u6570\u636e\u3002\u9884\u540e\u6a21\u578b\u9700\u8981\u660e\u786e\u7684\u672a\u6765\u7ed3\u5c40\u3001\u65f6\u95f4\u548c\u968f\u8bbf\u4fe1\u606f\uff1b\u8bca\u65ad\u6a21\u578b\u5173\u6ce8\u5f53\u524d\u72b6\u6001\u7684\u8bc6\u522b\uff0c\u9700\u8981\u53ef\u9760\u53c2\u8003\u6807\u51c6\u548c\u5408\u9002\u7684\u4eba\u7fa4\uff1b\u673a\u5236\u7814\u7a76\u5173\u6ce8\u5e72\u9884\u662f\u5426\u6539\u53d8\u8fc7\u7a0b\u53ca\u7ed3\u679c\u3002\u5148\u9009\u76ee\u6807\uff0c\u518d\u51b3\u5b9a\u5206\u6790\uff0c\u800c\u4e0d\u662f\u5148\u5957\u6a21\u677f\u518d\u5bfb\u627e\u7ed3\u8bba\u3002<\/p>\n","protected":false},"template":"","class_list":["post-65849","ftc_question","type-ftc_question","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/ftc_question\/65849","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/ftc_question"}],"about":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/types\/ftc_question"}],"version-history":[{"count":1,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/ftc_question\/65849\/revisions"}],"predecessor-version":[{"id":65869,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/ftc_question\/65849\/revisions\/65869"}],"wp:attachment":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/media?parent=65849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}