{"id":66400,"date":"2026-11-11T17:07:43","date_gmt":"2026-11-11T09:07:43","guid":{"rendered":"https:\/\/www.biocloudservice.com\/wordpress\/?p=66400"},"modified":"2026-11-11T17:07:43","modified_gmt":"2026-11-11T09:07:43","slug":"spatial-transcriptomics-presales-03-domains-cell-mapping","status":"publish","type":"post","link":"https:\/\/www.biocloudservice.com\/wordpress\/spatial-transcriptomics-presales-03-domains-cell-mapping\/","title":{"rendered":"\u7a7a\u95f4\u5206\u533a\u4e0e\u7ec6\u80de\u5b9a\u4f4d\uff1a\u600e\u6837\u628a\u7ec4\u7ec7\u54ea\u91cc\u4e0d\u540c\u8bb2\u6e05\u695a\uff1f\uff083\/5\uff09"},"content":{"rendered":"<style>#articleContent{max-width:900px;margin:auto;color:#26364a;font-size:17px;line-height:1.85;overflow-wrap:anywhere}#articleContent p{margin:17px 0}#articleContent h2{font-size:25px;line-height:1.5;color:#0868dc;border-left:5px solid #ff9b32;padding-left:14px;margin:38px 0 18px}#articleContent h3{font-size:19px;color:#174c83;margin:25px 0 8px}#articleContent 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href=\"https:\/\/www.biocloudservice.com\/wordpress\/spatial-transcriptomics-presales-01-analysis-overview\/\">\u5e38\u89c1\u5206\u6790\u603b\u89c8<\/a>\u548c<a href=\"https:\/\/www.biocloudservice.com\/wordpress\/spatial-transcriptomics-presales-02-project-readiness\/\">\u6837\u672c\u3001\u5e73\u53f0\u4e0e\u8d28\u91cf\u68c0\u67e5<\/a>\u3002\u672c\u7bc7\u805a\u7126\u901a\u8fc7\u521d\u6b65\u68c0\u67e5\u540e\uff0c\u5982\u4f55\u9009\u62e9\u533a\u57df\u548c\u7ec6\u80de\u76f8\u5173\u5206\u6790\u3002<\/p>\n<figure><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2026\/11\/spatial-presales-series-20261105-part-03-spatial-poster.png?resize=1200%2C680&#038;ssl=1\" width=\"1200\" height=\"680\" alt=\"\u7a7a\u95f4\u5206\u533a\u4e0e\u7ec6\u80de\u5b9a\u4f4d\u7684\u4e09\u6b65\u5224\u65ad\uff1a\u533a\u57df\u54ea\u91cc\u4e0d\u540c\u3001\u54ea\u4e9b\u7ec6\u80de\u5728\u54ea\u91cc\u3001\u7ec4\u6210\u53d8\u5316\u8fd8\u662f\u72b6\u6001\u53d8\u5316\uff1b\u5e26\u4e0a\u91cd\u70b9\u533a\u57df\u4e0e\u53c2\u8003\u6982\u51b5\u6c9f\u901a\u3002\"><figcaption>\u5206\u6790\u601d\u8def\u793a\u610f\uff0c\u975e\u5b9e\u9a8c\u7ed3\u679c\u3002\u5f69\u8272\u533a\u57df\u3001\u7ec6\u80de\u4e30\u5ea6\u4e0e\u529f\u80fd\u72b6\u6001\u9700\u8981\u5206\u522b\u89e3\u91ca\u3002<\/figcaption><\/figure>\n<h2>\u4e00\u3001\u5148\u628a\u4e09\u4e2a\u95ee\u9898\u5206\u5f00\uff0c\u624d\u77e5\u9053\u9700\u8981\u4ea4\u4ed8\u4ec0\u4e48<\/h2>\n<table class=\"stack-table\">\n<thead>\n<tr>\n<th scope=\"col\">\u5ba2\u6237\u60f3\u77e5\u9053\u4ec0\u4e48<\/th>\n<th scope=\"col\">\u5206\u6790\u4e0e\u4ea4\u4ed8\u793a\u4f8b<\/th>\n<th scope=\"col\">\u80fd\u63a8\u8fdb\u4ec0\u4e48\u5224\u65ad<\/th>\n<th scope=\"col\">\u9700\u8981\u8bf4\u6e05\u7684\u8fb9\u754c<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td data-label=\"\u5ba2\u6237\u60f3\u77e5\u9053\u4ec0\u4e48\">\u7ec4\u7ec7\u54ea\u91cc\u4e0d\u540c\uff1f<\/td>\n<td data-label=\"\u5206\u6790\u4e0e\u4ea4\u4ed8\u793a\u4f8b\">\u7a7a\u95f4\u5206\u533a\u56fe\u3001\u533a\u57df\u6807\u8bb0\u57fa\u56e0\u3001\u7ec4\u7ec7\u5f62\u6001\u53e0\u52a0\u56fe\u3002<\/td>\n<td data-label=\"\u80fd\u63a8\u8fdb\u4ec0\u4e48\u5224\u65ad\">\u5e2e\u52a9\u786e\u5b9a\u91cd\u70b9\u533a\u57df\u3001\u6bd4\u8f83\u5bf9\u8c61\u53ca\u540e\u7eed\u53d6\u6750\u4f4d\u7f6e\u3002<\/td>\n<td data-label=\"\u9700\u8981\u8bf4\u6e05\u7684\u8fb9\u754c\">\u8868\u8fbe\u805a\u7c7b\u662f\u5206\u7ec4\u7ed3\u679c\uff0c\u4e0d\u80fd\u81ea\u52a8\u547d\u540d\u4e3a\u67d0\u79cd\u75c5\u7406\u533a\u57df\u3002<a class=\"ref\" href=\"https:\/\/www.10xgenomics.com\/analysis-guides\/clustering-single-cell-spatial\">[1]<\/a><\/td>\n<\/tr>\n<tr>\n<td data-label=\"\u5ba2\u6237\u60f3\u77e5\u9053\u4ec0\u4e48\">\u5173\u6ce8\u7ec6\u80de\u5728\u54ea\u91cc\uff1f<\/td>\n<td data-label=\"\u5206\u6790\u4e0e\u4ea4\u4ed8\u793a\u4f8b\">\u7ec6\u80de\u6ce8\u91ca\u56fe\uff0c\u6216\u6df7\u5408spot\u4e2d\u7684\u7ec6\u80de\u7c7b\u578b\u4e30\u5ea6\u4f30\u8ba1\u3002<\/td>\n<td data-label=\"\u80fd\u63a8\u8fdb\u4ec0\u4e48\u5224\u65ad\">\u5224\u65ad\u76ee\u6807\u7ec6\u80de\u4e3b\u8981\u5206\u5e03\u5728\u75c5\u7076\u5185\u90e8\u3001\u8fb9\u7f18\u8fd8\u662f\u95f4\u8d28\u7b49\u533a\u57df\u3002<\/td>\n<td data-label=\"\u9700\u8981\u8bf4\u6e05\u7684\u8fb9\u754c\">\u5148\u533a\u5206\u5206\u5272\u7ec6\u80de\u4e0e\u6df7\u5408\u91c7\u6837\u70b9\uff1b\u4f30\u8ba1\u4e30\u5ea6\u4e0d\u7b49\u4e8e\u9010\u4e2a\u770b\u89c1\u771f\u5b9e\u7ec6\u80de\u3002<a class=\"ref\" href=\"https:\/\/cell2location.readthedocs.io\/en\/latest\/notebooks\/cell2location_tutorial.html\">[3]<\/a><\/td>\n<\/tr>\n<tr>\n<td data-label=\"\u5ba2\u6237\u60f3\u77e5\u9053\u4ec0\u4e48\">\u4e0d\u540c\u533a\u57df\u4e3a\u4ec0\u4e48\u6709\u5dee\u522b\uff1f<\/td>\n<td data-label=\"\u5206\u6790\u4e0e\u4ea4\u4ed8\u793a\u4f8b\">\u7ec6\u80de\u7ec4\u6210\u6bd4\u8f83\u3001\u533a\u57df\u5dee\u5f02\u8868\u8fbe\u3001\u53ef\u652f\u6301\u65f6\u7684\u540c\u7c7b\u7ec6\u80de\u72b6\u6001\u6bd4\u8f83\u3002<\/td>\n<td data-label=\"\u80fd\u63a8\u8fdb\u4ec0\u4e48\u5224\u65ad\">\u628a\u540e\u7eed\u9a8c\u8bc1\u7f29\u5c0f\u5230\u67d0\u7c7b\u7ec6\u80de\u3001\u67d0\u4e2a\u533a\u57df\u6216\u5019\u9009\u8868\u8fbe\u7a0b\u5e8f\u3002<\/td>\n<td 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class=\"ref\" 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class=\"ref\" href=\"https:\/\/cell2location.readthedocs.io\/en\/latest\/notebooks\/cell2location_tutorial.html\">[3]<\/a><a class=\"ref\" href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8606190\/\">[4]<\/a><\/p>\n<p>\u5177\u4f53\u89e3\u8bfb\u524d\u5fc5\u987b\u770b\u56fe\u4f8b\uff1a\u989c\u8272\u4ee3\u8868\u7684\u662f\u4e30\u5ea6\u3001\u6bd4\u4f8b\u3001\u6807\u7b7e\u5206\u6570\uff0c\u8fd8\u662f\u67d0\u79cd\u7f6e\u4fe1\u6307\u6807\uff1f\u8fd9\u4e9b\u6570\u503c\u4e0d\u80fd\u4e92\u6362\u3002cell2location\u6559\u7a0b\u4e2d\u7684\u4e30\u5ea6\u4f30\u8ba1\u4f9d\u8d56\u6a21\u578b\u4e0e\u5148\u9a8c\uff0c\u5e76\u63d0\u4f9b\u5206\u5e03\u5206\u4f4d\u6570\u548c\u8d28\u91cf\u68c0\u67e5\uff1b\u5b83\u4e0d\u662f\u4eba\u5de5\u663e\u5fae\u8ba1\u6570\uff0c\u4e5f\u4e0d\u5e94\u76f4\u63a5\u628a\u4efb\u610f\u70ed\u56fe\u5f3a\u5ea6\u5199\u6210\u7ec6\u80de\u6570\u91cf\u3002<\/p>\n<h3>\u6ca1\u6709\u914d\u5957\u5355\u7ec6\u80de\u6570\u636e\uff0c\u5c31\u5b8c\u5168\u4e0d\u80fd\u505a\u5417\uff1f<\/h3>\n<p>\u4e0d\u5fc5\u4e00\u7968\u5426\u51b3\u3002\u7a7a\u95f4\u5206\u533a\u3001\u5df2\u77e5\u6807\u8bb0\u5c55\u793a\u548c\u90e8\u5206\u533a\u57df\u6bd4\u8f83\uff0c\u901a\u5e38\u4e0d\u4ee5\u914d\u5957\u5355\u7ec6\u80de\u53c2\u8003\u4e3a\u5fc5\u9700\u524d\u63d0\u3002\u82e5\u60f3\u8fdb\u884c\u4f9d\u8d56\u53c2\u8003\u7684\u7ec6\u80de\u89e3\u5377\u79ef\uff0c\u53ef\u4ee5\u5148\u8bc4\u4f30\u53ef\u6bd4\u516c\u5171\u53c2\u8003\uff0c\u4f46\u9700\u8981\u6838\u5bf9\u7269\u79cd\u3001\u7ec4\u7ec7\u3001\u75be\u75c5\u6216\u5904\u7406\u72b6\u6001\u3001\u7ec6\u80de\u7c7b\u578b\u8986\u76d6\u548c\u6ce8\u91ca\u8d28\u91cf\u3002<\/p>\n<p>\u53c2\u8003\u4e0e\u7a7a\u95f4\u6570\u636e\u5e76\u975e\u4e00\u5b9a\u8981\u6765\u81ea\u540c\u4e00\u4f9b\u4f53\uff1b\u5173\u952e\u662f\u80fd\u5426\u4ee3\u8868\u5f85\u5206\u6790\u7684\u7ec6\u80de\u7ec4\u6210\u3002\u53c2\u8003\u4e2d\u6ca1\u6709\u7684\u7c7b\u578b\uff0c\u4e0d\u80fd\u671f\u5f85\u6a21\u578b\u81ea\u52a8\u6b63\u786e\u8865\u5168\u3002RCTD\u539f\u7814\u7a76\u5c31\u5c55\u793a\u4e86\u7f3a\u5931\u7ec6\u80de\u7c7b\u578b\u53ef\u80fd\u88ab\u5206\u914d\u7ed9\u53c2\u8003\u4e2d\u76f8\u4f3c\u7c7b\u578b\u7684\u60c5\u51b5\u3002\u4fe1\u53f7\u76f8\u8fd1\u3001\u53c2\u8003\u7f3a\u5931\u6216\u4e9a\u578b\u96be\u5206\u65f6\uff0c\u5148\u8003\u8651\u66f4\u7c97\u7684\u5206\u7c7b\u3001\u8865\u5145\u53c2\u8003\u6216\u4fdd\u7559\u672a\u786e\u5b9a\u6807\u7b7e\u3002<a class=\"ref\" href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8606190\/\">[4]<\/a><\/p>\n<p>\u56e0\u6b64\uff0c\u552e\u524d\u7684\u4e0b\u4e00\u6b65\u4e0d\u662f\u201c\u5148\u7ed9\u6bcf\u4e2aspot\u8d34\u4e00\u4e2a\u7ec6\u80de\u540d\u201d\uff0c\u800c\u662f\u5148\u786e\u5b9a\u5e0c\u671b\u5206\u5230\u4ec0\u4e48\u5c42\u7ea7\uff0c\u4ee5\u53ca\u73b0\u6709\u8bc1\u636e\u80fd\u5426\u652f\u6491\u8fd9\u4e2a\u5c42\u7ea7\u3002<\/p>\n<h2>\u56db\u3001\u533a\u57df\u5dee\u5f02\uff1a\u5148\u95ee\u662f\u7ec6\u80de\u591a\u4e86\uff0c\u8fd8\u662f\u7ec6\u80de\u72b6\u6001\u53d8\u4e86<\/h2>\n<p>\u4e0b\u9762\u662f\u4e00\u4e2a\u5047\u8bbe\u573a\u666f\uff1a\u533a\u57dfA\u7684\u514d\u75ab\u76f8\u5173\u57fa\u56e0\u9ad8\u4e8e\u533a\u57dfB\u3002\u53ef\u4ee5\u5148\u68c0\u67e5A\u4e2d\u514d\u75ab\u7ec6\u80de\u662f\u5426\u66f4\u591a\uff1b\u82e5\u7ec4\u6210\u5df2\u7ecf\u4e0d\u540c\uff0c\u6574\u4f53\u4fe1\u53f7\u589e\u5f3a\u672a\u5fc5\u610f\u5473\u7740\u6bcf\u4e2a\u514d\u75ab\u7ec6\u80de\u90fd\u66f4\u6d3b\u8dc3\u3002\u82e5\u8981\u8fdb\u4e00\u6b65\u8ba8\u8bba\u72b6\u6001\uff0c\u5e94\u5728\u53ef\u9760\u7684\u7ec6\u80de\u7c7b\u578b\u548c\u6570\u636e\u652f\u6301\u4e0b\uff0c\u6bd4\u8f83\u540c\u7c7b\u7ec6\u80de\u6216\u91c7\u7528\u5408\u9002\u7684\u7ec4\u6210\u6821\u6b63\u3001\u7ec6\u80de\u7c7b\u578b\u7279\u5f02\u5206\u6790\uff0c\u5e76\u4fdd\u7559\u6a21\u578b\u5c40\u9650\u3002<\/p>\n<p><strong>\u201c\u7a7a\u95f4\u53d8\u5f02\u57fa\u56e0\u201d\u4e0e\u201c\u533a\u57df\u5dee\u5f02\u57fa\u56e0\u201d\u4e5f\u4e0d\u540c\u3002<\/strong>\u524d\u8005\u5bfb\u627e\u8868\u8fbe\u968f\u4f4d\u7f6e\u53d8\u5316\u7684\u6a21\u5f0f\uff0c\u4f8b\u5982\u68af\u5ea6\u3001\u6591\u5757\u6216\u5c42\u72b6\u5206\u5e03\uff1b\u540e\u8005\u56f4\u7ed5\u4e8b\u5148\u6307\u5b9a\u7684\u533a\u57df\u505a\u6bd4\u8f83\u3002\u4e00\u4e2a\u57fa\u56e0\u5177\u6709\u7a7a\u95f4\u6a21\u5f0f\uff0c\u4e0d\u7b49\u4e8e\u5b83\u5c31\u662f\u75be\u75c5\u76f8\u5173\u57fa\u56e0\uff0c\u4e5f\u4e0d\u7b49\u4e8e\u5728\u5ba2\u6237\u6307\u5b9a\u7684\u4e24\u4e2a\u533a\u57df\u95f4\u6709\u540c\u6837\u5dee\u5f02\u3002<a class=\"ref\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29553579\/\">[5]<\/a><a class=\"ref\" href=\"https:\/\/www.10xgenomics.com\/support\/software\/space-ranger\/latest\/algorithms-overview\/gene-expression\">[6]<\/a><\/p>\n<p>\u529f\u80fd\u5bcc\u96c6\u6216\u57fa\u56e0\u96c6\u8bc4\u5206\u53ef\u4ee5\u5e2e\u52a9\u6982\u62ec\u5019\u9009\u8868\u8fbe\u7a0b\u5e8f\uff0c\u4f46\u8981\u770b\u6709\u6548\u68c0\u6d4b\u57fa\u56e0\u662f\u5426\u8986\u76d6\u76f8\u5173\u96c6\u5408\u3002\u5c24\u5176\u662f\u9776\u5411\u9762\u677f\uff0c\u7f3a\u6d4b\u57fa\u56e0\u4e0d\u5e94\u5f53\u4f5c\u771f\u5b9e\u4f4e\u8868\u8fbe\uff1b\u80cc\u666f\u57fa\u56e0\u96c6\u4e5f\u5e94\u4e0e\u5b9e\u9645\u53ef\u68c0\u6d4b\u8303\u56f4\u76f8\u7b26\u3002\u7531\u6b64\u5f97\u5230\u7684\u662f\u8868\u8fbe\u5c42\u9762\u7684\u7ebf\u7d22\uff0c\u4e0d\u80fd\u76f4\u63a5\u5199\u6210\u86cb\u767d\u6d3b\u6027\u6216\u673a\u5236\u5df2\u88ab\u8bc1\u5b9e\u3002<\/p>\n<p>\u5f53\u5ba2\u6237\u8981\u6bd4\u8f83\u75be\u75c5\u7ec4\u4e0e\u5bf9\u7167\u7ec4\u65f6\uff0c\u8fd8\u9700\u8981\u56de\u5230\u72ec\u7acb\u4e2a\u4f53\u548c\u5207\u7247\u5c42\u7ea7\u3002\u7ec6\u80de\u3001spot\u5f88\u591a\uff0c\u4e0d\u4f1a\u81ea\u52a8\u8865\u4e0a\u751f\u7269\u5b66\u91cd\u590d\uff1b\u7a7a\u95f4\u76f8\u5173\u6027\u548c\u6279\u6b21\u4e5f\u9700\u7eb3\u5165\u5206\u6790\u8bbe\u8ba1\u3002\u53ea\u6709\u5c11\u91cf\u4e2a\u4f53\u65f6\uff0c\u533a\u57df\u89c2\u5bdf\u53ef\u4ee5\u5e2e\u52a9\u5f62\u6210\u5047\u8bbe\uff0c\u4f46\u63a8\u5e7f\u4e3a\u7fa4\u4f53\u5dee\u5f02\u8981\u8c28\u614e\u3002<a class=\"ref\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34584091\/\">[7]<\/a><\/p>\n<h2>\u4e94\u3001\u8fd9\u4e94\u7c7b\u95ee\u9898\uff0c\u524d\u7aef\u53ef\u4ee5\u8fd9\u6837\u5904\u7406<\/h2>\n<table class=\"stack-table\">\n<thead>\n<tr>\n<th scope=\"col\">\u5ba2\u6237\u63d0\u51fa\u7684\u95ee\u9898<\/th>\n<th scope=\"col\">\u5148\u68c0\u67e5\u4ec0\u4e48<\/th>\n<th scope=\"col\">\u5efa\u8bae\u63aa\u65bd\u4e0e\u6c9f\u901a\u91cd\u70b9<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td data-label=\"\u5ba2\u6237\u63d0\u51fa\u7684\u95ee\u9898\">\u201c\u5206\u51fa\u7684\u533a\u57df\u4e0e\u75c5\u7406\u6807\u6ce8\u4e0d\u4e00\u81f4\uff0c\u662f\u4e0d\u662f\u7b97\u6cd5\u9519\u4e86\uff1f\u201d<\/td>\n<td data-label=\"\u5148\u68c0\u67e5\u4ec0\u4e48\">\u5750\u6807\u914d\u51c6\u3001\u8d28\u91cf\u3001\u6807\u8bb0\u8bc1\u636e\u548c\u5206\u533a\u53c2\u6570\uff0c\u4ee5\u53ca\u4e24\u8005\u662f\u5426\u5728\u63cf\u8ff0\u540c\u4e00\u5c42\u7ea7\u3002<\/td>\n<td data-label=\"\u5efa\u8bae\u63aa\u65bd\u4e0e\u6c9f\u901a\u91cd\u70b9\">\u5148\u590d\u6838\uff0c\u518d\u89e3\u91ca\u4e00\u81f4\u4e0e\u4e0d\u4e00\u81f4\u7684\u90e8\u5206\uff1b\u4e0d\u4e3a\u4e86\u5bf9\u9f50\u75c5\u7406\u56fe\u800c\u786c\u8c03\u53c2\u6570\uff0c\u4e5f\u4e0d\u76f4\u63a5\u5426\u5b9a\u75c5\u7406\u5224\u65ad\u3002<\/td>\n<\/tr>\n<tr>\n<td data-label=\"\u5ba2\u6237\u63d0\u51fa\u7684\u95ee\u9898\">\u201c\u56fe\u4e0a\u67d0\u79cd\u7ec6\u80de\u5f88\u5c11\uff0c\u80fd\u5426\u8bf4\u660e\u5b83\u4e0d\u5b58\u5728\uff1f\u201d<\/td>\n<td data-label=\"\u5148\u68c0\u67e5\u4ec0\u4e48\">\u68c0\u6d4b\u8986\u76d6\u3001\u76ee\u6807\u4fe1\u53f7\u3001\u53c2\u8003\u662f\u5426\u7f3a\u5931\u3001\u5206\u7c7b\u4e0d\u786e\u5b9a\u6027\u3002<\/td>\n<td data-label=\"\u5efa\u8bae\u63aa\u65bd\u4e0e\u6c9f\u901a\u91cd\u70b9\">\u5148\u8bf4\u660e\u4f4e\u4fe1\u53f7\u6216\u4f30\u8ba1\u8f83\u5c11\uff1b\u9700\u8981\u6392\u9664\u67d0\u7c7b\u7ec6\u80de\u65f6\uff0c\u8865\u72ec\u7acb\u6807\u8bb0\u6216\u7ec4\u7ec7\u9a8c\u8bc1\u3002<\/td>\n<\/tr>\n<tr>\n<td data-label=\"\u5ba2\u6237\u63d0\u51fa\u7684\u95ee\u9898\">\u201c\u4e24\u5f20\u70ed\u56fe\u989c\u8272\u5dee\u4e0d\u591a\uff0c\u4e30\u5ea6\u5c31\u662f\u4e00\u6837\u5417\uff1f\u201d<\/td>\n<td data-label=\"\u5148\u68c0\u67e5\u4ec0\u4e48\">\u6570\u503c\u542b\u4e49\u3001\u8272\u6807\u8303\u56f4\u3001\u5f52\u4e00\u5316\u65b9\u5f0f\u3001\u7ec4\u7ec7\u9762\u79ef\u548c\u7ec6\u80de\u5bc6\u5ea6\u3002<\/td>\n<td data-label=\"\u5efa\u8bae\u63aa\u65bd\u4e0e\u6c9f\u901a\u91cd\u70b9\">\u6838\u5bf9\u53ef\u6bd4\u6027\u5e76\u63d0\u4f9b\u5b9a\u91cf\u6c47\u603b\uff1b\u4e0d\u80fd\u4ec5\u51ed\u5404\u81ea\u81ea\u52a8\u7f29\u653e\u7684\u989c\u8272\u6bd4\u8f83\u3002<\/td>\n<\/tr>\n<tr>\n<td data-label=\"\u5ba2\u6237\u63d0\u51fa\u7684\u95ee\u9898\">\u201c\u628a\u5355\u7ec6\u80de\u91cc\u7684\u6240\u6709\u4e9a\u7fa4\u90fd\u5b9a\u4f4d\u51fa\u6765\uff0c\u53ef\u4ee5\u5417\uff1f\u201d<\/td>\n<td data-label=\"\u5148\u68c0\u67e5\u4ec0\u4e48\">\u7ec6\u5206\u7c7b\u522b\u662f\u5426\u6709\u53ef\u533a\u5206\u4fe1\u53f7\uff0c\u7a7a\u95f4\u6570\u636e\u4e0e\u53c2\u8003\u662f\u5426\u5339\u914d\u3002<\/td>\n<td data-label=\"\u5efa\u8bae\u63aa\u65bd\u4e0e\u6c9f\u901a\u91cd\u70b9\">\u4f18\u5148\u53ef\u9760\u5927\u7c7b\uff0c\u518d\u8bc4\u4f30\u91cd\u70b9\u4e9a\u7fa4\uff1b\u96be\u4ee5\u533a\u5206\u65f6\u5408\u5e76\u6216\u6807\u6ce8\u4e0d\u786e\u5b9a\uff0c\u4e0d\u627f\u8bfa\u5168\u90e8\u7cbe\u7ec6\u5b9a\u4f4d\u3002<\/td>\n<\/tr>\n<tr>\n<td data-label=\"\u5ba2\u6237\u63d0\u51fa\u7684\u95ee\u9898\">\u201c\u533a\u57df\u529f\u80fd\u8bc4\u5206\u9ad8\uff0c\u80fd\u5426\u4f5c\u4e3a\u673a\u5236\u7ed3\u8bba\uff1f\u201d<\/td>\n<td data-label=\"\u5148\u68c0\u67e5\u4ec0\u4e48\">\u57fa\u56e0\u8986\u76d6\u3001\u7ec4\u6210\u5dee\u5f02\u3001\u8bc4\u5206\u65b9\u6cd5\u548c\u72ec\u7acb\u8bc1\u636e\u3002<\/td>\n<td data-label=\"\u5efa\u8bae\u63aa\u65bd\u4e0e\u6c9f\u901a\u91cd\u70b9\">\u628a\u7ed3\u679c\u4f5c\u4e3a\u5f85\u9a8c\u8bc1\u7a0b\u5e8f\uff0c\u660e\u786e\u5019\u9009\u7ec6\u80de\u4e0e\u533a\u57df\uff0c\u7ee7\u7eed\u5b89\u6392\u86cb\u767d\u3001\u539f\u4f4d\u6216\u529f\u80fd\u9a8c\u8bc1\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>\u516d\u3001\u7b2c\u4e00\u6b21\u6c9f\u901a\uff0c\u5c31\u628a\u4ea4\u4ed8\u63a5\u5230\u4e0b\u4e00\u6b65\u7814\u7a76<\/h2>\n<p>\u53ef\u5148\u8bf7\u5ba2\u6237\u63d0\u4f9b\uff1a\u6700\u5173\u6ce8\u7684\u533a\u57df\u548c\u7ec6\u80de\u3001\u533a\u57df\u5982\u4f55\u5b9a\u4e49\u3001\u5e73\u53f0\u53ca\u5206\u6790\u5355\u4f4d\u3001\u662f\u5426\u6709\u75c5\u7406\u6807\u6ce8\u6216\u914d\u5957\u53c2\u8003\u3001\u72ec\u7acb\u6837\u672c\u60c5\u51b5\uff0c\u4ee5\u53ca\u5df2\u6709\u5019\u9009\u3002\u6d89\u53ca\u654f\u611f\u8d44\u6599\u65f6\u5148\u63d0\u4f9b\u6982\u51b5\u6216\u53ef\u5206\u4eab\u7684\u793a\u610f\u56fe\uff0c\u6b63\u5f0f\u6570\u636e\u53e6\u884c\u7ea6\u5b9a\u4f20\u8f93\u65b9\u5f0f\u3002<\/p>\n<p>\u5efa\u8bae\u628a\u4ea4\u4ed8\u5199\u6210\u201c\u533a\u57df\u56fe\u53ca\u547d\u540d\u4f9d\u636e\u3001\u7ec6\u80de\u5b9a\u4f4d\u4e0e\u4e0d\u786e\u5b9a\u6027\u8bf4\u660e\u3001\u91cd\u70b9\u6bd4\u8f83\u548c\u5019\u9009\u6e05\u5355\u3001\u9002\u5408\u7684\u540e\u7eed\u9a8c\u8bc1\u65b9\u5411\u201d\u3002\u6bcf\u9879\u7ed3\u679c\u90fd\u5bf9\u5e94\u4e00\u4e2a\u95ee\u9898\uff0c\u4e0d\u4ee5\u56fe\u7247\u6570\u91cf\u66ff\u4ee3\u8bfe\u9898\u4ef7\u503c\uff0c\u4e5f\u4e0d\u627f\u8bfa\u6240\u6709\u4e9a\u578b\u90fd\u80fd\u533a\u5206\u3002<\/p>\n<blockquote><p>\u201c\u6211\u4eec\u53ef\u4ee5\u5148\u5e2e\u60a8\u660e\u786e\u54ea\u4e9b\u533a\u57df\u503c\u5f97\u6bd4\u8f83\uff0c\u5173\u6ce8\u7ec6\u80de\u4e3b\u8981\u4f4d\u4e8e\u54ea\u91cc\uff0c\u518d\u5224\u65ad\u5dee\u5f02\u66f4\u50cf\u662f\u7ec6\u80de\u7ec4\u6210\u53d8\u5316\uff0c\u8fd8\u662f\u540c\u7c7b\u7ec6\u80de\u72b6\u6001\u53d8\u5316\u3002\u80fd\u5b9a\u4f4d\u5230\u591a\u7ec6\uff0c\u8981\u770b\u5e73\u53f0\u3001\u4fe1\u53f7\u548c\u53c2\u8003\u662f\u5426\u652f\u6301\u3002\u7ed3\u679c\u4f1a\u9644\u5224\u65ad\u4f9d\u636e\u53ca\u4e0d\u786e\u5b9a\u90e8\u5206\uff0c\u5e2e\u52a9\u60a8\u9009\u51fa\u4e0b\u4e00\u6b65\u503c\u5f97\u9a8c\u8bc1\u7684\u533a\u57df\u548c\u5019\u9009\u3002\u201d<\/p><\/blockquote>\n<p>\u4e91\u751f\u4fe1\u53ef\u5148\u56f4\u7ed5\u91cd\u70b9\u7ec6\u80de\u4e0e\u533a\u57df\uff0c\u6c9f\u901a\u6570\u636e\u662f\u5426\u652f\u6301\u5b9a\u4f4d\u6216\u6bd4\u8f83\uff0c\u518d\u786e\u8ba4\u5206\u6790\u65b9\u6cd5\u3001\u4ea4\u4ed8\u8303\u56f4\u548c\u9700\u8981\u8865\u5145\u7684\u8bc1\u636e\u3002<\/p>\n<p><a class=\"cta\" data-ysx-event=\"contact_click\" href=\"https:\/\/work.weixin.qq.com\/kfid\/kfcb05492f29d4d6064\">\u5e26\u4e0a\u91cd\u70b9\u533a\u57df\u4e0e\u53c2\u8003\u6982\u51b5\uff0c\u6c9f\u901a\u5206\u6790\u8303\u56f4<\/a><\/p>\n<p class=\"next\">\u4e0b\u4e00\u7bc7\uff1a\u7ec6\u80de\u90bb\u57df\u4e0e\u7a7a\u95f4\u901a\u8baf\u3002\u628a\u201c\u54ea\u4e9b\u7ec6\u80de\u5728\u4e00\u8d77\u201d\u63a8\u8fdb\u5230\u201c\u54ea\u4e9b\u5173\u7cfb\u503c\u5f97\u9a8c\u8bc1\u201d\uff0c\u5e76\u8bb2\u6e05\u76f8\u90bb\u3001\u901a\u8baf\u63a8\u65ad\u4e0e\u673a\u5236\u8bc1\u636e\u7684\u5dee\u522b\u3002<\/p>\n<h2>\u8d44\u6599\u4f9d\u636e<\/h2>\n<p>\u6838\u5bf9\u65e5\u671f\uff1a2026\u5e7411\u670811\u65e5\u3002\u65b9\u6cd5\u8bf4\u660e\u4f9d\u636e\u539f\u59cb\u7814\u7a76\u548c\u5b98\u65b9\u6587\u6863\uff1b\u6c9f\u901a\u573a\u666f\u53ca\u5904\u7406\u987a\u5e8f\u4e3a\u9879\u76ee\u5efa\u8bae\uff0c\u4e0d\u662f\u7edf\u4e00\u8f6f\u4ef6\u51c6\u5165\u6807\u51c6\u3002<\/p>\n<ol>\n<li><a href=\"https:\/\/www.10xgenomics.com\/analysis-guides\/clustering-single-cell-spatial\">10x\uff1a\u7a7a\u95f4\u805a\u7c7b\u3001\u7ec6\u80de\u6ce8\u91ca\u4e0e\u4e0d\u540c\u5206\u6790\u5355\u4f4d<\/a><\/li>\n<li><a href=\"https:\/\/github.com\/jianhuupenn\/SpaGCN\">SpaGCN\u4f5c\u8005\u4ed3\u5e93\uff1a\u7ed3\u5408\u8868\u8fbe\u3001\u4f4d\u7f6e\u548c\u7ec4\u7ec7\u56fe\u50cf\u8bc6\u522b\u7a7a\u95f4\u533a\u57df<\/a><\/li>\n<li><a href=\"https:\/\/cell2location.readthedocs.io\/en\/latest\/notebooks\/cell2location_tutorial.html\">cell2location\u4f5c\u8005\u6559\u7a0b\uff1a\u53c2\u8003\u8868\u8fbe\u3001\u4e30\u5ea6\u4f30\u8ba1\u4e0e\u8d28\u91cf\u68c0\u67e5<\/a><\/li>\n<li><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8606190\/\">RCTD\u539f\u59cb\u7814\u7a76\uff1a\u7ec6\u80de\u6df7\u5408\u5206\u89e3\u4e0e\u53c2\u8003\u7f3a\u5931\u7684\u5c40\u9650<\/a><\/li>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29553579\/\">SpatialDE\u539f\u59cb\u7814\u7a76\uff1a\u7a7a\u95f4\u53d8\u5f02\u57fa\u56e0\u7684\u542b\u4e49<\/a><\/li>\n<li><a href=\"https:\/\/www.10xgenomics.com\/support\/software\/space-ranger\/latest\/algorithms-overview\/gene-expression\">Space Ranger\uff1a\u8868\u8fbe\u5206\u6790\u3001\u533a\u57df\u5dee\u5f02\u4e0e\u7a7a\u95f4\u5bcc\u96c6<\/a><\/li>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34584091\/\">Squair\u7b49\uff1a\u5dee\u5f02\u5206\u6790\u4e2d\u7684\u751f\u7269\u5b66\u91cd\u590d<\/a><\/li>\n<\/ol>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u7ed9\u552e\u524d\u6280\u672f\u8001\u5e08\u7684\u7a7a\u95f4\u5206\u533a\u4e0e\u7ec6\u80de\u5b9a\u4f4d\u6307\u5357\uff1a\u533a\u57df\u5206\u533a\u3001\u6df7\u5408spot\u89e3\u5377\u79ef\u3001\u533a\u57df\u5dee\u5f02\u53ca\u529f\u80fd\u72b6\u6001\u5206\u522b\u80fd\u56de\u7b54\u4ec0\u4e48\uff0c\u5982\u4f55\u533a\u5206\u7ec4\u6210\u53d8\u5316\u4e0e\u72b6\u6001\u53d8\u5316\uff1b\u9644\u5e38\u89c1\u95ee\u9898\u5904\u7406\u63aa\u65bd\u548c\u5ba2\u6237\u8bdd\u672f\u3002<\/p>\n","protected":false},"author":1,"featured_media":66399,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[1,71],"tags":[473,87,474,379,475,476],"class_list":["post-66400","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-part","category-single-cell","tag-473","tag-87","tag-474","tag-379","tag-475","tag-476"],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2026\/11\/spatial-presales-series-20261105-part-03-spatial-poster.png?fit=1200%2C680&ssl=1","_links":{"self":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/66400","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/comments?post=66400"}],"version-history":[{"count":1,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/66400\/revisions"}],"predecessor-version":[{"id":66401,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/66400\/revisions\/66401"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/media\/66399"}],"wp:attachment":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/media?parent=66400"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/categories?post=66400"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/tags?post=66400"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}