{"id":68222,"date":"2026-11-14T20:25:06","date_gmt":"2026-11-14T12:25:06","guid":{"rendered":"https:\/\/www.biocloudservice.com\/wordpress\/?p=68222"},"modified":"2026-11-14T22:01:35","modified_gmt":"2026-11-14T14:01:35","slug":"celltypist-majority-voting-rare-label-audit","status":"publish","type":"post","link":"https:\/\/www.biocloudservice.com\/wordpress\/celltypist-majority-voting-rare-label-audit\/","title":{"rendered":"CellTypist \u591a\u6570\u6295\u7968\u4e4b\u540e\u7a00\u6709\u7ec6\u80de\u6d88\u5931\u4e86\uff0c\u600e\u6837\u67e5\u662f\u7ea0\u9519\u8fd8\u662f\u8bef\u5e76\uff1f"},"content":{"rendered":"<div class=\"ysx-method-guide\" style=\"max-width:820px;min-width:0;margin:0 auto;color:#26374a;line-height:1.86;overflow-wrap:anywhere\">\n<p>\u540c\u4e00\u6279\u514d\u75ab\u7ec6\u80de\uff0cCellTypist \u9010\u7ec6\u80de\u9884\u6d4b\u80fd\u627e\u5230\u5341\u51e0\u679a\u6811\u7a81\u72b6\u7ec6\u80de\uff0c\u5f00\u542f\u591a\u6570\u6295\u7968\u4e4b\u540e\u5374\u4e00\u4e2a\u90fd\u6ca1\u6709\u4e86\u3002\u56fe\u4e0a\u7684\u6807\u7b7e\u770b\u8d77\u6765\u66f4\u6574\u9f50\uff0c\u5b9e\u9a8c\u4eba\u5458\u53cd\u800c\u5173\u5fc3\u90a3\u5341\u51e0\u679a\u7a76\u7adf\u662f\u4ec0\u4e48\u3002\u8981\u5224\u65ad\u8fd9\u6b21\u6539\u53d8\uff0c\u81f3\u5c11\u8981\u4fdd\u7559\u4e09\u5217\u4fe1\u606f\uff0c\u6bcf\u679a\u7ec6\u80de\u539f\u6765\u53eb\u4f5c\u4ec0\u4e48\u3001\u6295\u5728\u54ea\u4e2a\u5c0f\u7c07\u3001\u6295\u7968\u540e\u6539\u6210\u4ec0\u4e48\u3002\u8fd8\u9700\u8981\u518d\u770b\u4e00\u5c42\u539f\u59cb\u8868\u8fbe\u8bc1\u636e\uff0c\u5f04\u6e05\u88ab\u6539\u540d\u7684\u5c11\u6570\u7ec6\u80de\u7a76\u7adf\u662f\u96f6\u6563\u8bef\u5224\uff0c\u8fd8\u662f\u5177\u6709\u76f8\u540c\u7279\u5f81\u7684\u4e00\u7fa4\u3002<\/p>\n<h2 style=\"font-size:1.38em;line-height:1.5;margin:1.55em 0 .55em;color:#182d43\">\u5148\u786e\u8ba4\u6a21\u578b\u80fd\u89c1\u5230\u4ec0\u4e48<\/h2>\n<p>\u901a\u7528\u6a21\u578b\u6765\u81ea\u7279\u5b9a\u8bad\u7ec3\u6750\u6599\uff0c\u6709\u81ea\u5df1\u7684\u7269\u79cd\u3001\u7ec4\u7ec7\u8303\u56f4\u548c\u6807\u7b7e\u5c42\u7ea7\u3002\u4e00\u4efd\u53ea\u6db5\u76d6\u514d\u75ab\u7cfb\u7edf\u7684\u6a21\u578b\u5373\u4f7f\u53ef\u4ee5\u7ed9\u4e0a\u76ae\u7ec6\u80de\u8f93\u51fa\u4e00\u4e2a\u6700\u4f73\u5339\u914d\uff0c\u90a3\u4e2a\u6807\u7b7e\u4e5f\u96be\u4ee5\u89e3\u91ca\u4e3a\u53ef\u9760\u7684\u4e0a\u76ae\u4e9a\u578b\u3002\u5f00\u59cb\u524d\u67e5\u770b\u6a21\u578b\u81ea\u5e26\u7684\u7ec6\u80de\u7c7b\u578b\u5217\u8868\u548c\u8bad\u7ec3\u80cc\u666f\uff0c\u5217\u51fa\u4f60\u9884\u671f\u51fa\u73b0\u800c\u6a21\u578b\u5b8c\u5168\u6ca1\u6709\u7684\u7c7b\u578b\u3002\u82e5\u9879\u76ee\u5305\u542b\u80bf\u7624\u7ec6\u80de\u3001\u57fa\u8d28\u7ec6\u80de\u548c\u514d\u75ab\u7ec6\u80de\uff0c\u53ef\u5148\u533a\u5206\u5927\u8c31\u7cfb\uff0c\u518d\u628a\u9002\u5408\u7684\u514d\u75ab\u5b50\u96c6\u4ea4\u7ed9\u76f8\u5e94\u6a21\u578b\uff0c\u4fdd\u7559\u5176\u4f59\u90e8\u5206\u7684\u72ec\u7acb\u6ce8\u91ca\u4f9d\u636e\u3002<\/p>\n<p>\u63a5\u7740\u67e5\u77e9\u9635\u3002\u5bf9\u4f20\u5165\u7684 AnnData\uff0c\u9879\u76ee\u6587\u6863\u8981\u6c42\u5408\u9002\u7684\u6309\u7ec6\u80de\u603b\u91cf\u5f52\u4e00\u5316\u5e76\u53d6\u81ea\u7136\u5bf9\u6570\u52a0\u4e00\u7684\u8868\u8fbe\u77e9\u9635\uff0c\u5f52\u4e00\u5316\u76ee\u6807\u4e3a\u4e00\u4e07\u3002\u5b83\u4f1a\u67e5\u770b\u4e3b\u77e9\u9635\uff0c\u5728\u4e0d\u5408\u9002\u65f6\u8fd8\u53ef\u80fd\u68c0\u67e5\u539f\u59cb\u5feb\u7167\u3002\u8fd9\u91cc\u7684\u540d\u5b57\u5e76\u4e0d\u4fdd\u8bc1\u5185\u5bb9\uff0c\u66fe\u7ecf\u7f29\u653e\u6210\u6709\u8d1f\u6570\u7684\u6807\u51c6\u5316\u8868\u8fbe\u4e0d\u80fd\u56e0\u4e3a\u653e\u5728\u4e3b\u77e9\u9635\u4e2d\u5c31\u7b26\u5408\u8981\u6c42\u3002\u4e5f\u8981\u5c3d\u91cf\u63d0\u4f9b\u5b8c\u6574\u57fa\u56e0\u96c6\u5408\uff0c\u63d0\u524d\u53ea\u4fdd\u7559\u5c11\u91cf\u9ad8\u53d8\u57fa\u56e0\u4f1a\u4f7f\u8bad\u7ec3\u6a21\u578b\u4e2d\u7684\u4e00\u4e9b\u6807\u8bb0\u5931\u53bb\u89c2\u6d4b\u3002\u7528\u7a33\u5b9a\u7684\u6765\u6e90\u8bb0\u5f55\u8ffd\u6eaf\u5f52\u4e00\u5316\u6b65\u9aa4\uff0c\u518d\u6838\u5bf9\u8f93\u5165\u7684\u57fa\u56e0\u7b26\u53f7\u4e0e\u6a21\u578b\u7684\u4ea4\u96c6\u3002<a style=\"color:#795a91;text-decoration:underline;text-underline-offset:2px\" href=\"https:\/\/github.com\/Teichlab\/celltypist\">CellTypist \u4f5c\u8005\u7684\u8f93\u5165\u548c\u6a21\u578b\u8bf4\u660e<\/a><\/p>\n<h2 style=\"font-size:1.38em;line-height:1.5;margin:1.55em 0 .55em;color:#182d43\">\u9010\u7ec6\u80de\u9884\u6d4b\u548c\u7c07\u5185\u6295\u7968\u662f\u4e24\u6b21\u4e0d\u540c\u7684\u51b3\u7b56<\/h2>\n<p>\u6700\u4f73\u5339\u914d\u6a21\u5f0f\u4f1a\u4ece\u5019\u9009\u7c7b\u522b\u4e2d\u53d6\u5206\u6570\u6700\u9ad8\u7684\u4e00\u7c7b\u3002\u67d0\u4e00\u7ec6\u80de\u7684\u6700\u9ad8\u5206\u5373\u4f7f\u5e76\u4e0d\u7a81\u51fa\uff0c\u4e5f\u4f9d\u7136\u6709\u7b2c\u4e00\u540d\u3002\u53e6\u4e00\u79cd\u6982\u7387\u5339\u914d\u6a21\u5f0f\u53ef\u6309\u9608\u503c\u7ed9\u51fa\u96f6\u4e2a\u3001\u4e00\u4e2a\u6216\u591a\u4e2a\u5019\u9009\u6807\u7b7e\u3002\u5728\u6700\u4f73\u5339\u914d\u6a21\u5f0f\u4e0b\u8c03\u6574\u8fd9\u4e2a\u591a\u6807\u7b7e\u9608\u503c\u5e76\u4e0d\u4f1a\u8fbe\u5230\u7b5b\u53bb\u5f31\u9884\u6d4b\u7684\u76ee\u7684\u3002\u591a\u6570\u6295\u7968\u5219\u5728\u9010\u7ec6\u80de\u7ed3\u679c\u4e4b\u540e\u8fdb\u884c\uff0c\u5b83\u5c06\u5c5e\u4e8e\u540c\u4e00\u7ec6\u5206\u7c07\u7684\u6807\u7b7e\u653e\u5728\u4e00\u8d77\uff0c\u6309\u5360\u6bd4\u786e\u5b9a\u8be5\u7c07\u7684\u547d\u540d\u3002\u9009\u62e9\u600e\u6837\u7684\u7ec6\u5206\u7c07\uff0c\u76f4\u63a5\u5f71\u54cd\u6709\u65e0\u673a\u4f1a\u4fdd\u4f4f\u7a00\u6709\u7c7b\u578b\u3002<a style=\"color:#795a91;text-decoration:underline;text-underline-offset:2px\" href=\"https:\/\/celltypist.readthedocs.io\/en\/latest\/celltypist.annotate.html\">\u9884\u6d4b\u6a21\u5f0f\u3001\u6295\u7968\u548c\u6700\u4f4e\u5360\u6bd4\u53c2\u6570<\/a><\/p>\n<p>\u5047\u8bbe\u4e00\u4e2a\u6559\u5b66\u5c0f\u7c07\u6709\u5341\u4e8c\u679a\u7ec6\u80de\u3002\u5355\u7ec6\u80de\u5c42\u9762\u516b\u679a\u53eb\u7532\u3001\u56db\u679a\u53eb\u4e59\uff0c\u7532\u5360\u4e09\u5206\u4e4b\u4e8c\u3002\u5982\u679c\u6ca1\u6709\u66f4\u9ad8\u7684\u5360\u6bd4\u8981\u6c42\uff0c\u8fd9\u4e2a\u7c07\u53ef\u7edf\u4e00\u53eb\u7532\uff0c\u4e8e\u662f\u539f\u5148\u56db\u679a\u4e59\u5728\u6295\u7968\u6807\u7b7e\u91cc\u90fd\u53d8\u6210\u7532\u3002\u82e5\u8981\u6c42\u80dc\u8005\u81f3\u5c11\u5360\u56db\u5206\u4e4b\u4e09\uff0c\u8fd9\u4e2a\u7c07\u8fbe\u4e0d\u5230\u8981\u6c42\uff0c\u5c06\u88ab\u6807\u4e3a\u5f02\u8d28\u3002\u7b2c\u4e09\u79cd\u60c5\u5f62\u662f\u5148\u7528\u72ec\u7acb\u6807\u8bb0\u548c\u90bb\u5c45\u5173\u7cfb\u53d1\u73b0\u4e59\u5728\u5185\u90e8\u672c\u6765\u5f62\u6210\u8fde\u8d2f\u7684\u5c0f\u7fa4\uff0c\u518d\u5c06\u8fd9\u4e2a\u5c0f\u7fa4\u4f5c\u4e3a\u6709\u4f9d\u636e\u7684\u7ec6\u5206\u533a\u57df\u3002\u65b0\u7684\u6295\u7968\u7ed3\u679c\u53ef\u80fd\u6709\u52a9\u4e8e\u4fdd\u7559\u4e59\uff0c\u4f46\u4e5f\u8981\u9632\u6b62\u4e3a\u4e86\u5f97\u5230\u60f3\u770b\u7684\u6807\u7b7e\u4efb\u610f\u5207\u5206\u3002<\/p>\n<div class=\"guide-table\" style=\"max-width:100%;overflow-x:auto;margin:18px 0\">\n<table style=\"display:table;width:100%;max-width:100%;min-width:0;table-layout:fixed;border-collapse:collapse;font-size:.92em;line-height:1.6\">\n<thead>\n<tr>\n<th scope=\"col\" style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;background:#f8f0fc;color:#1e293b;vertical-align:top;text-align:left;padding:6px;border:1px solid #c4cfdb\">\u540c\u4e00\u6279\u5341\u4e8c\u679a\u7ec6\u80de<\/th>\n<th scope=\"col\" style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;background:#f8f0fc;color:#1e293b;vertical-align:top;text-align:left;padding:6px;border:1px solid #c4cfdb\">\u5360\u6bd4\u6216\u5206\u7ec4<\/th>\n<th scope=\"col\" style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;background:#f8f0fc;color:#1e293b;vertical-align:top;text-align:left;padding:6px;border:1px solid #c4cfdb\">\u600e\u6837\u8bfb\u7ed3\u679c<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">\u76f4\u63a5\u6309\u539f\u7c07\u6295\u7968<\/td>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">\u7532 8 \/ 12\uff0c\u4e59 4 \/ 12<\/td>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">\u7532\u5360\u591a\u6570\uff0c\u56db\u679a\u4e59\u53ef\u88ab\u6539\u540d<\/td>\n<\/tr>\n<tr>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">\u80dc\u8005\u81f3\u5c11\u5360 75%<\/td>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">8 \/ 12 \u5c0f\u4e8e 75%<\/td>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">\u6574\u7c07\u6807\u6210\u5f02\u8d28\uff0c\u9700\u8981\u7ee7\u7eed\u68c0\u67e5<\/td>\n<\/tr>\n<tr>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">\u5728\u6709\u6807\u8bb0\u652f\u6301\u7684\u5b50\u7fa4\u91cc\u590d\u6838<\/td>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">\u5206\u522b\u770b\u539f\u9884\u6d4b\u548c\u771f\u5b9e\u6807\u8bb0<\/td>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">\u4f18\u5148\u5224\u65ad\u56db\u679a\u4e59\u662f\u5426\u6784\u6210\u4e00\u81f4\u7684\u5c0f\u7fa4<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<figure class=\"guide-figure\" style=\"margin:24px 0 28px\"><img loading=\"lazy\" decoding=\"async\" src=\"\/wordpress\/wp-content\/uploads\/2026\/11\/celltypist-majority-voting-rare-label-audit-guide.png\" alt=\"\u56db\u679a\u7a00\u6709\u7ec6\u80de\u662f\u600e\u6837\u88ab\u6539\u540d\u7684\u3002\u6559\u5b66\u7b97\u4f8b\uff5c\u540c\u4e00\u4e2a\u7ec6\u5206\u7c07\u91cc\uff0c\u9010\u7ec6\u80de\u9884\u6d4b\u7ed9\u51fa\u516b\u7968\u7532\u3001\u56db\u7968\u4e59\u30028 \/ 12\uff0c\u5728\u539f\u7c07\u76f4\u63a5\u6295\u7968\uff0c\u7532\u4e3a\u591a\u6570\uff0c\u4e59\u7684\u56db\u4e2a\u6761\u5f62\u7801\u53ef\u4ee5\u4e00\u540c\u88ab\u6539\u540d\u300275%\uff0c\u63d0\u9ad8\u6700\u4f4e\u652f\u6301\u6bd4\u4f8b\uff0c\u6700\u9ad8\u5360\u6bd4\u7ea6 67%\uff0c\u8fd9\u4e2a\u7c07\u5c06\u88ab\u6807\u4e3a\u5f02\u8d28\u3002\u67e5\u56db\u679a\uff0c\u53c2\u8003\u539f\u59cb\u8868\u8fbe\u548c\u4f9b\u4f53\uff0c\u6210\u7ec4\u67e5\u770b\u8c31\u7cfb\u6807\u8bb0\uff0c\u533a\u5206\u8bef\u5224\u4e0e\u771f\u5b9e\u7a00\u6709\u72b6\u6001\u3002\" width=\"1200\" height=\"840\" style=\"display:block;width:100%;height:auto;border-radius:10px\"><figcaption style=\"font-size:14px;line-height:1.6;margin:9px 2px 0;color:#475569\">\u6559\u5b66\u7b97\u4f8b\uff5c\u540c\u4e00\u4e2a\u7ec6\u5206\u7c07\u91cc\uff0c\u9010\u7ec6\u80de\u9884\u6d4b\u7ed9\u51fa\u516b\u7968\u7532\u3001\u56db\u7968\u4e59\u3002<\/figcaption><\/figure>\n<h2 style=\"font-size:1.38em;line-height:1.5;margin:1.55em 0 .55em;color:#182d43\">\u5bfc\u51fa\u6539\u540d\u6e05\u5355\uff0c\u8ffd\u5230\u5177\u4f53\u6761\u5f62\u7801<\/h2>\n<p>\u4e0b\u9762\u5047\u8bbe\u5bf9\u8c61\u91cc\u5df2\u7ecf\u6709\u6838\u5b9e\u8fc7\u7684\u7ec6\u5206\u6807\u7b7e\uff0c\u6240\u9009\u6a21\u578b\u9002\u7528\u4e8e\u8fd9\u6279\u514d\u75ab\u7ec6\u80de\u3002\u4fdd\u7559\u9010\u7ec6\u80de\u6807\u7b7e\uff0c\u540c\u65f6\u5355\u72ec\u5217\u51fa\u6295\u7968\u7ed3\u679c\u4e0e\u539f\u6807\u7b7e\u51b2\u7a81\u7684\u6761\u5f62\u7801\uff0c\u518d\u5c06\u5176\u4e0e\u5206\u5b50\u6570\u3001\u4f9b\u4f53\u3001\u6807\u8bb0\u8868\u8fbe\u8fde\u63a5\u3002\u4e00\u4e2a\u6837\u672c\u5185\u91cd\u590d\u7528\u540c\u4e00\u4e2a\u6761\u5f62\u7801\u547d\u540d\u5e76\u4e0d\u7f55\u89c1\uff0c\u8de8\u6837\u672c\u62fc\u63a5\u524d\u5e94\u628a\u6587\u5e93\u6807\u8bc6\u7eb3\u5165\u7ec6\u80de\u540d\u3002<\/p>\n<pre style=\"max-width:100%;box-sizing:border-box;overflow-x:auto;margin:18px 0;padding:14px 16px;background:#f3f6fa;color:#1a293c;border:1px solid #d8e1ea;border-radius:8px;line-height:1.55;white-space:pre;overflow-wrap:normal;word-break:normal\"><code class=\"language-python\">import celltypist\r\n\r\nres = celltypist.annotate(adata, model=&quot;Immune_All_Low.pkl&quot;,\r\n                          majority_voting=True, over_clustering=&quot;subcluster&quot;)\r\nlabels = res.predicted_labels.copy()\r\nchanged = labels.loc[labels[&quot;predicted_labels&quot;] != labels[&quot;majority_voting&quot;]]\r\nprint(changed.groupby([&quot;predicted_labels&quot;, &quot;majority_voting&quot;],\r\n                      observed=True).size())\r\n<\/code><\/pre>\n<p>\u56de\u5230\u4e0a\u9762\u7684\u56db\u679a\u4e59\uff0c\u5148\u770b\u5b83\u4eec\u662f\u5426\u90fd\u68c0\u51fa\u540c\u4e00\u7ec4\u8c31\u7cfb\u6807\u8bb0\u3001\u662f\u5426\u603b\u5206\u5b50\u6570\u8db3\u4ee5\u4f5c\u5224\u65ad\uff0c\u518d\u67e5\u770b\u56db\u679a\u6765\u81ea\u4e00\u4e2a\u4f9b\u4f53\u8fd8\u662f\u591a\u6b21\u72ec\u7acb\u53d6\u6750\u3002\u5047\u5982\u56db\u679a\u53ea\u5728\u4f4e\u8d28\u91cf\u533a\u57df\u96f6\u661f\u51fa\u73b0\uff0c\u6bcf\u679a\u652f\u6301\u4e59\u7684\u57fa\u56e0\u53c8\u5b8c\u5168\u4e0d\u540c\uff0c\u6295\u7968\u7ea0\u6b63\u96f6\u6563\u8bef\u5224\u662f\u53ef\u89e3\u91ca\u7684\u3002\u82e5\u56db\u679a\u96c6\u4e2d\u4e8e\u6709\u6e05\u695a\u5b9a\u4f4d\u7684\u90bb\u57df\uff0c\u5728\u4e0d\u540c\u4f9b\u4f53\u90fd\u80fd\u590d\u73b0\u540c\u4e00\u7ec4\u6b63\u6807\u8bb0\uff0c\u5e76\u4e14\u7f3a\u4e4f\u7532\u7684\u5173\u952e\u7279\u5f81\uff0c\u628a\u5b83\u4eec\u4e00\u5f8b\u5e76\u5165\u7532\u4f1a\u62b9\u53bb\u503c\u5f97\u9a8c\u8bc1\u7684\u7fa4\u4f53\u3002\u6b64\u65f6\u53ef\u4ee5\u4fdd\u7559\u5230\u5927\u7c7b\uff0c\u628a\u7ec6\u5206\u7c7b\u6ce8\u660e\u5f85\u6838\u5b9e\uff0c\u518d\u7528\u53e6\u4e00\u4efd\u5408\u9002\u7684\u53c2\u8003\u6216\u86cb\u767d\u6807\u8bb0\u4f5c\u4ea4\u53c9\u68c0\u67e5\u3002<\/p>\n<p>\u8fd8\u53ef\u4ee5\u6309\u7ec6\u80de\u6807\u8bc6\u62ff\u56de\u6240\u6709\u7c7b\u522b\u7684\u51b3\u7b56\u5206\u6570\uff0c\u5bf9\u6bd4\u6539\u540d\u524d\u6392\u5728\u524d\u4e24\u4f4d\u7684\u6a21\u578b\u6807\u7b7e\u3002\u82e5\u56db\u679a\u7ec6\u80de\u5bf9\u4e59\u7684\u652f\u6301\u90fd\u5f88\u7a81\u51fa\uff0c\u5374\u53ea\u56e0\u6240\u5728\u7ec6\u5206\u7c07\u8303\u56f4\u592a\u5927\u800c\u88ab\u6539\u540d\uff0c\u4e0b\u4e00\u6b21\u5e94\u4f18\u5148\u590d\u6838\u90bb\u5c45\u56fe\u4e0e\u7ec6\u5206\u7c07\u3002\u5982\u679c\u8fde\u539f\u59cb\u5206\u6570\u90fd\u5f88\u63a5\u8fd1\uff0c\u5219\u5148\u6838\u5bf9\u6a21\u578b\u7f3a\u5931\u7c7b\u522b\u548c\u771f\u6b63\u6709\u533a\u5206\u529b\u7684\u6807\u8bb0\u3002<\/p>\n<h2 style=\"font-size:1.38em;line-height:1.5;margin:1.55em 0 .55em;color:#182d43\">\u5b9e\u8dd1\u7ecf\u9a8c\uff5c\u9010\u7ec6\u80de\u5168\u5224\u5bf9\uff0c\u6295\u7968\u540e\u4e3a\u4ec0\u4e48\u6539\u9519\u5341\u4e09\u679a<\/h2>\n<p>\u6211\u4eec\u5b89\u88c5 CellTypist 1.7.1\uff0c\u5728\u4e8c\u5341\u56db\u4e2a\u6a21\u62df\u57fa\u56e0\u3001\u4e00\u767e\u4e8c\u5341\u679a\u8bad\u7ec3\u7ec6\u80de\u4e0a\u8bad\u7ec3\u4e00\u4e2a\u4e24\u7c7b\u6a21\u578b\u3002\u67e5\u8be2\u96c6\u53e6\u884c\u62bd\u6837\uff0c\u5171\u516d\u5341\u679a\u7ec6\u80de\uff0c\u7ed9\u6bcf\u79cd\u7c7b\u578b\u516d\u4e2a\u660e\u663e\u6807\u8bb0\u3002\u6211\u4eec\u7528\u4e24\u4e2a\u5404\u4e09\u5341\u679a\u7684\u4eba\u5de5\u7ec6\u5206\u7fa4\u505a\u8bca\u65ad\uff0c\u7b2c\u4e00\u4e2a\u542b\u4e8c\u5341\u4e00\u7532\u3001\u4e5d\u4e59\uff0c\u7b2c\u4e8c\u4e2a\u542b\u56db\u7532\u3001\u4e8c\u5341\u516d\u4e59\u3002\u9010\u7ec6\u80de\u5206\u7c7b\u516d\u5341\u679a\u5168\u90e8\u4e0e\u8bbe\u5b9a\u76f8\u7b26\u3002\u5141\u8bb8\u7b80\u5355\u591a\u6570\u6295\u7968\u540e\uff0c\u7b2c\u4e00\u7fa4\u5168\u5199\u7532\uff0c\u7b2c\u4e8c\u7fa4\u5168\u5199\u4e59\uff0c\u5171\u5341\u4e09\u679a\u88ab\u6539\u540d\uff0c\u4fdd\u7559\u6b63\u786e\u6807\u7b7e\u56db\u5341\u4e03\u679a\u3002\u5c06\u6700\u5c0f\u5360\u6bd4\u8bbe\u4e3a\u96f6\u70b9\u516b\uff0c\u7b2c\u4e00\u7fa4\u7684\u4e03\u6210\u591a\u6570\u672a\u8fc7\u7ebf\uff0c\u4e09\u5341\u679a\u90fd\u6807\u4f5c Heterogeneous\uff0c\u7b2c\u4e8c\u7fa4\u4ecd\u5168\u6807\u4e59\u3002\u8fd9\u65f6\u5e94\u5206\u522b\u62a5\u544a\u672a\u51b3\u6570\u548c\u4fdd\u7559\u7684\u5177\u4f53\u6807\u7b7e\uff0c\u907f\u514d\u5c06\u672a\u51b3\u786c\u7b97\u6210\u7b2c\u4e09\u79cd\u7ec6\u80de\u3002<\/p>\n<p>\u53c8\u4ece\u540c\u4e00\u67e5\u8be2\u96c6\u53d6\u524d\u4e94\u5341\u679a\uff0c\u63d0\u4f9b\u76f8\u540c\u7ec6\u5206\u5217\u3001\u5f00\u542f\u6295\u7968\u3002\u8fd9\u4e2a\u7248\u672c\u7684\u9ad8\u5c42\u9884\u6d4b\u51fd\u6570\u5728\u8f93\u5165\u6570\u76ee\u4e0d\u8d85\u8fc7\u4e94\u5341\u65f6\u8df3\u8fc7\u6295\u7968\uff0c\u8fd4\u56de\u8868\u53ea\u6709\u9010\u7ec6\u80de\u6807\u7b7e\uff0c\u65e5\u5fd7\u660e\u786e\u7ed9\u51fa\u4e86\u539f\u56e0\u3002\u56e0\u6b64\u521a\u62ff\u5341\u51e0\u679a\u7ec6\u80de\u505a\u5c0f\u6d4b\u8bd5\u65f6\uff0c\u5e94\u5148\u6253\u5370\u8fd4\u56de\u5217\uff0c\u800c\u4e0d\u80fd\u6307\u671b\u603b\u6709\u6295\u7968\u7ed3\u679c\u53ef\u4f9b\u5bf9\u7167\u3002\u8bad\u7ec3\u9636\u6bb5\u4e5f\u9047\u5230\u8fc7\u7248\u672c\u5dee\u5f02\uff0c\u8f83\u65b0\u5206\u7c7b\u5e93\u4e0d\u63a5\u53d7\u6b64\u5b9e\u73b0\u4f7f\u7528\u7684 multi_class \u53c2\u6570\uff0c\u6211\u4eec\u7528 scikit-learn 1.5.2 \u5b8c\u6210\u8bad\u7ec3\u3002\u8be5\u5b9e\u8dd1\u662f\u7528\u72ec\u7acb\u751f\u6210\u7684\u6570\u636e\u68c0\u9a8c\u6295\u7968\u673a\u5236\uff0c\u6ca1\u6709\u636e\u6b64\u8bc4\u4f30\u4eba\u7c7b\u514d\u75ab\u53c2\u8003\u6a21\u578b\u7684\u6ce8\u91ca\u6027\u80fd\u3002<a style=\"color:#795a91;text-decoration:underline;text-underline-offset:2px\" href=\"https:\/\/github.com\/Teichlab\/celltypist\/blob\/main\/celltypist\/annotate.py\">\u4f5c\u8005\u9ad8\u5c42\u9884\u6d4b\u63a5\u53e3\u7684\u5b9e\u73b0<\/a><\/p>\n<h2 style=\"font-size:1.38em;line-height:1.5;margin:1.55em 0 .55em;color:#182d43\">\u600e\u6837\u4f30\u8ba1\u5bf9\u7ed3\u679c\u7a76\u7adf\u6709\u591a\u5927\u5f71\u54cd<\/h2>\n<p>\u6309\u4f9b\u4f53\u505a\u4e24\u5f20\u7ec4\u6210\u8868\uff0c\u4e00\u5f20\u4f7f\u7528\u9010\u7ec6\u80de\u6700\u4f73\u5339\u914d\uff0c\u4e00\u5f20\u4f7f\u7528\u6295\u7968\u540e\u7684\u6807\u7b7e\uff0c\u53e6\u5217\u6709\u591a\u5c11\u6761\u5f62\u7801\u4ece\u54ea\u4e00\u7c7b\u6d41\u5411\u54ea\u4e00\u7c7b\u3002\u5927\u7c7b\u603b\u91cf\u53ef\u80fd\u51e0\u4e4e\u4e0d\u53d8\uff0c\u800c\u67d0\u4e00\u4e2a\u7a00\u6709\u7c7b\u578b\u4ece\u4e8c\u5341\u679a\u51cf\u5c11\u5230\u96f6\uff0c\u8fd9\u4e24\u79cd\u73b0\u8c61\u53ef\u4ee5\u540c\u65f6\u53d1\u751f\u3002\u5982\u679c\u62a5\u544a\u6cbb\u7597\u524d\u540e\u7a00\u6709\u7fa4\u6bd4\u4f8b\uff0c\u8fd8\u8981\u5728\u6bcf\u4f4d\u4f9b\u4f53\u5185\u5355\u72ec\u8ba1\u7b97\uff0c\u800c\u4e0d\u662f\u5c06\u5404\u7ec4\u7ec6\u80de\u7b80\u5355\u6c47\u603b\u3002\u4e00\u4e2a\u7ec6\u80de\u6570\u7279\u522b\u591a\u7684\u4f9b\u4f53\u8db3\u4ee5\u63a7\u5236\u5408\u5e76\u8d8b\u52bf\u3002\u9009\u62e9\u6ce8\u91ca\u65b9\u6848\u65f6\uff0c\u5e94\u4ee5\u6807\u8bb0\u548c\u72ec\u7acb\u91cd\u590d\u63d0\u4f9b\u7684\u8bc1\u636e\u4e3a\u51c6\uff0c\u4e0d\u5b9c\u6309\u6cbb\u7597\u5dee\u5f02\u54ea\u6b21\u66f4\u663e\u8457\u6765\u6311\u7ed3\u679c\u3002<\/p>\n<p>\u6700\u540e\u7279\u522b\u770b\u4e00\u773c\u540c\u4e00\u7269\u79cd\u4e0d\u540c\u7ec4\u7ec7\u4e4b\u95f4\u7684\u72b6\u6001\u5dee\u522b\u3002\u4e00\u4e2a\u5728\u5916\u5468\u8840\u91cc\u7a33\u5b9a\u7684\u6807\u8bb0\uff0c\u8fdb\u5165\u7ec4\u7ec7\u540e\u53ef\u80fd\u53d7\u6d3b\u5316\u6539\u53d8\u3002\u6a21\u578b\u628a\u80bf\u7624\u6837\u672c\u91cc\u7684\u67d0\u4e2a\u7fa4\u4f53\u5206\u7ed9\u4e24\u4e2a\u76f8\u5173\u6807\u7b7e\u65f6\uff0c\u53ef\u4ee5\u5148\u590d\u6838\u5171\u540c\u8c31\u7cfb\u8eab\u4efd\uff0c\u518d\u7528\u7ec4\u7ec7\u7279\u5f02\u6807\u8bb0\u8865\u5145\u7ec6\u5206\u3002\u8bb0\u5f55\u6a21\u578b\u540d\u79f0\u548c\u7248\u672c\u3001\u57fa\u56e0\u8986\u76d6\u3001\u6295\u7968\u6240\u7528\u7ec6\u5206\u5217\u4e0e\u5360\u6bd4\u8981\u6c42\uff0c\u8fd9\u6837\u4e0b\u6b21\u52a0\u5165\u65b0\u6837\u672c\u51fa\u73b0\u547d\u540d\u53d8\u5316\u65f6\uff0c\u80fd\u627e\u5230\u5177\u4f53\u662f\u54ea\u4e2a\u6761\u4ef6\u53d1\u751f\u4e86\u6539\u53d8\u3002<\/p>\n<p class=\"guide-end\" style=\"margin-top:1.6em;padding-top:1.0em;border-top:1px solid #d7e0e9\">\u82e5\u4e00\u9879\u7ed3\u8bba\u6d89\u53ca\u5c11\u6570\u5173\u952e\u7ec6\u80de\uff0c\u968f\u7ed3\u679c\u9644\u4e0a\u5b83\u4eec\u7684\u6761\u5f62\u7801\u3001\u539f\u59cb\u6807\u7b7e\u3001\u6295\u7968\u6807\u7b7e\u548c\u6807\u8bb0\u590d\u6838\u8868\uff0c\u5b9e\u9a8c\u540c\u4e8b\u53ef\u4ee5\u660e\u786e\u6311\u54ea\u4e00\u7fa4\u505a\u9a8c\u8bc1\u3002\u56e2\u961f\u9700\u8981\u4e3a\u4e0d\u540c\u7ec4\u7ec7\u91cd\u590d\u6bd4\u8f83\u6a21\u578b\u5e76\u4fdd\u7559\u539f\u59cb\u5bf9\u8c61\u65f6\uff0c\u53ef\u4e86\u89e3<a data-ysx-event=\"contact_click\" style=\"color:#795a91;text-decoration:underline;text-underline-offset:2px\" href=\"https:\/\/www.biocloudservice.com\/wordpress\/compute-services\/shared-research-workspace\/\">\u4e91\u751f\u4fe1\u7684\u751f\u7269\u4fe1\u606f\u5206\u6790\u670d\u52a1\u5668<\/a>\u3002<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u7528\u5341\u4e8c\u679a\u7ec6\u80de\u89e3\u91ca\u591a\u6570\u6295\u7968\u548c\u6700\u4f4e\u652f\u6301\u6bd4\u4f8b\uff0c\u5bfc\u51fa\u88ab\u6539\u540d\u7684\u6761\u5f62\u7801\uff0c\u5224\u65ad\u7a00\u6709\u7fa4\u662f\u5426\u503c\u5f97\u4fdd\u7559\u3002<\/p>\n","protected":false},"author":1,"featured_media":68221,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[49,71],"tags":[703,704,705],"class_list":["post-68222","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-software","category-single-cell","tag-celltypist","tag-704","tag-705"],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2026\/11\/celltypist-majority-voting-rare-label-audit-guide.png?fit=1200%2C840&ssl=1","_links":{"self":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/68222","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/comments?post=68222"}],"version-history":[{"count":2,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/68222\/revisions"}],"predecessor-version":[{"id":69880,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/68222\/revisions\/69880"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/media\/68221"}],"wp:attachment":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/media?parent=68222"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/categories?post=68222"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/tags?post=68222"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}