{"id":69447,"date":"2026-11-14T21:27:02","date_gmt":"2026-11-14T13:27:02","guid":{"rendered":"https:\/\/www.biocloudservice.com\/wordpress\/?p=69447"},"modified":"2026-11-14T21:27:02","modified_gmt":"2026-11-14T13:27:02","slug":"spotlight-nmf-pure-controls-mixture-residuals","status":"publish","type":"post","link":"https:\/\/www.biocloudservice.com\/wordpress\/spotlight-nmf-pure-controls-mixture-residuals\/","title":{"rendered":"SPOTlight \u7684\u997c\u56fe\u52a0\u8d77\u6765\u6b63\u597d\u662f 100%\uff0c\u4e3a\u4ec0\u4e48\u7eaf\u6837\u672c\u4e5f\u4f1a\u753b\u6210\u4e09\u5757\uff1f"},"content":{"rendered":"
\n

\u5982\u679c\u5df2\u7ecf\u77e5\u9053\u67d0\u4e2a\u7a7a\u95f4\u70b9\u53ea\u6709\u4e00\u79cd\u7ec6\u80de\uff0c\u628a\u5b83\u4ea4\u7ed9\u53cd\u5377\u79ef\u7a0b\u5e8f\uff0c\u7ed3\u679c\u8fd8\u4f1a\u51fa\u73b0\u53e6\u5916\u4e24\u79cd\u7ec6\u80de\u5417\uff1f\u8fd9\u662f\u68c0\u9a8c SPOTlight \u7279\u522b\u503c\u5f97\u505a\u7684\u4e00\u9053\u9898\u3002\u8f93\u51fa\u7684\u6bcf\u4e00\u884c\u90fd\u53ef\u4ee5\u89c4\u6574\u5730\u52a0\u5230\u4e00\uff0c\u4f46\u8fd9\u53ea\u8bf4\u660e\u7b97\u6cd5\u628a\u7ed3\u679c\u8868\u8fbe\u6210\u4e86\u6bd4\u4f8b\u3002\u4e3a\u4e86\u68c0\u9a8c\u7b97\u6cd5\u80fd\u4e0d\u80fd\u5206\u5bf9\uff0c\u53ef\u4ee5\u7528\u5355\u7ec6\u80de\u53c2\u8003\u6784\u9020\u51e0\u4e2a\u6765\u6e90\u660e\u786e\u7684\u7a7a\u95f4\u6df7\u5408\u7269\uff0c\u5148\u770b\u7eaf\u7532\u3001\u7eaf\u4e59\u548c\u7eaf\u4e19\uff0c\u518d\u770b\u6bd4\u4f8b\u5df2\u77e5\u7684\u6df7\u5408\u70b9\u3002\u8fd9\u6837\u624d\u80fd\u77e5\u9053\u5360\u6bd4\u51e0\u4e4e\u76f8\u540c\u7684\u4e24\u5757\u989c\u8272\uff0c\u7a76\u7adf\u53cd\u6620\u4e86\u6837\u672c\uff0c\u8fd8\u662f\u5f53\u524d\u8bbe\u7f6e\u672c\u5c31\u96be\u4ee5\u628a\u5b83\u4eec\u5206\u5f00\u3002<\/p>\n

\u8ba9\u6807\u8bb0\u7ed9\u4e3b\u9898\u4e00\u4e2a\u8d77\u70b9\uff0c\u518d\u770b\u6a21\u578b\u5b66\u51fa\u4e86\u4ec0\u4e48<\/h2>\n

SPOTlight \u5148\u7528\u7ec6\u80de\u7c7b\u578b\u6807\u8bb0\u7ed9\u975e\u8d1f\u77e9\u9635\u5206\u89e3\u63d0\u4f9b\u521d\u59cb\u4fe1\u606f\uff0c\u5b66\u5230\u4e00\u7ec4\u57fa\u56e0\u8868\u8fbe\u4e3b\u9898\u4ee5\u53ca\u7ec6\u80de\u5728\u8fd9\u4e9b\u4e3b\u9898\u4e0a\u7684\u8868\u793a\u3002\u518d\u5229\u7528\u53c2\u8003\u7c7b\u578b\u4e0e\u4e3b\u9898\u7684\u5bf9\u5e94\u5173\u7cfb\uff0c\u5bf9\u7a7a\u95f4\u89c2\u6d4b\u505a\u975e\u8d1f\u56de\u5f52\u3002\u975e\u8d1f\u7684\u6761\u4ef6\u4f7f\u4f30\u8ba1\u4e0d\u80fd\u9760\u4e00\u4e2a\u5f88\u5927\u7684\u6b63\u503c\u548c\u53e6\u4e00\u4e2a\u8d1f\u503c\u76f8\u4e92\u62b5\u6d88\uff0c\u8f93\u51fa\u6bd4\u8f83\u5bb9\u6613\u89e3\u91ca\u3002\u4f46\u201c\u7532\u7c7b\u6807\u8bb0\u53c2\u4e0e\u521d\u59cb\u5316\u201d\u4e0d\u7b49\u4e8e\u6700\u540e\u67d0\u4e2a\u4e3b\u9898\u53ea\u4ee3\u8868\u7532\u7c7b\u3002\u4e00\u4e2a\u5f3a\u70c8\u589e\u6b96\u6216\u5e94\u6fc0\u7a0b\u5e8f\u53ef\u4ee5\u5728\u51e0\u79cd\u7c7b\u578b\u4e2d\u540c\u65f6\u51fa\u73b0\uff0c\u6b64\u65f6\u4e3b\u9898\u4e5f\u53ef\u80fd\u8de8\u7c7b\u578b\u3002\u753b\u7ed3\u679c\u4e4b\u524d\uff0c\u8981\u628a\u4e3b\u9898\u5728\u4e0d\u540c\u771f\u5b9e\u53c2\u8003\u7c7b\u578b\u4e2d\u7684\u5206\u5e03\u5355\u72ec\u770b\u4e00\u904d\u3002SPOTlight \u5728 Bioconductor \u7684\u65b9\u6cd5\u4e0e\u63a5\u53e3\u8bf4\u660e<\/a><\/p>\n

\u6807\u8bb0\u5217\u8868\u6700\u597d\u4fdd\u7559\u57fa\u56e0\u3001\u6240\u5c5e\u7c7b\u578b\u548c\u6743\u91cd\u4e09\u5217\uff0c\u5e76\u8bb0\u5f55\u5b83\u6765\u81ea\u54ea\u4efd\u53c2\u8003\u3002\u82e5\u67d0\u4e00\u7c7b\u578b\u7684\u9ad8\u6743\u91cd\u6807\u8bb0\u5168\u6765\u81ea\u5355\u4e2a\u4f9b\u4f53\uff0c\u5b83\u4eec\u53ef\u80fd\u6807\u8bb0\u8fd9\u4e2a\u4eba\u7684\u6837\u672c\u5904\u7406\u6761\u4ef6\u3002\u53ef\u4ee5\u5148\u6bd4\u8f83\u4e0d\u540c\u4f9b\u4f53\u4e2d\u540c\u540d\u7c7b\u578b\u7684\u8868\u8fbe\u65b9\u5411\uff0c\u518d\u7b5b\u51fa\u7a7a\u95f4\u5e73\u53f0\u4e5f\u786e\u5b9e\u80fd\u6d4b\u5230\u7684\u6807\u8bb0\u3002\u4e0d\u80fd\u7528\u5728\u5355\u7ec6\u80de\u53c2\u8003\u4e2d\u975e\u5e38\u7279\u5f02\u3001\u5374\u5728\u6574\u5f20\u5207\u7247\u4e0a\u4ece\u672a\u68c0\u51fa\u7684\u57fa\u56e0\u6765\u89e3\u91ca\u7a7a\u95f4\u5206\u5e03\u3002\u76f8\u4f3c\u4e9a\u7fa4\u53ef\u4ee5\u6682\u65f6\u5408\u5e76\u6210\u8f83\u7c97\u7c7b\u522b\uff0c\u4e4b\u540e\u7528\u6709\u8db3\u591f\u72ec\u7acb\u8bc1\u636e\u7684\u5207\u7247\u518d\u5c1d\u8bd5\u7ec6\u5206\u3002<\/p>\n

\u505a\u4e00\u4efd\u77e5\u9053\u7b54\u6848\u7684\u7a7a\u95f4\u6df7\u5408\u7269<\/h2>\n

\u4ece\u53c2\u8003\u4e2d\u62bd\u53d6\u8ba1\u6570\uff0c\u6784\u9020\u7532\u4e59\u4e19\u4e09\u4e2a\u7eaf\u70b9\uff0c\u518d\u6784\u9020\u5df2\u77e5\u7532\u4e59\u4e19\u8d21\u732e\u7684\u6df7\u5408\u70b9\u3002\u5c0f\u89c4\u6a21\u7684\u7b2c\u4e00\u8f6e\u53ef\u4ee5\u7528\u6bcf\u7c7b\u5e73\u5747\u8868\u8fbe\uff0c\u6309\u7ed9\u5b9a\u6743\u91cd\u76f8\u52a0\uff0c\u89c2\u5bdf\u63a5\u53e3\u548c\u5f52\u4e00\u5316\u662f\u5426\u6309\u9884\u671f\u5de5\u4f5c\u3002\u7b2c\u4e8c\u8f6e\u5219\u4ece\u672a\u53c2\u52a0\u8bad\u7ec3\u7684\u4f9b\u4f53\u4e2d\u62bd\u7ec6\u80de\u6df7\u5408\uff0c\u4fdd\u7559\u62bd\u4e2d\u7684\u7ec6\u80de\u7f16\u53f7\u548c\u5404\u81ea\u603b\u5206\u5b50\u6570\u3002\u540e\u4e00\u79cd\u8bd5\u9a8c\u540c\u65f6\u4f1a\u9047\u5230\u7ec6\u80de\u5927\u5c0f\u4e0e\u6d4b\u5e8f\u6df1\u5ea6\u4e0d\u540c\u7684\u95ee\u9898\uff0c\u540c\u6837\u4e94\u679a\u7ec6\u80de\u7684\u5206\u5b50\u8d21\u732e\u53ef\u80fd\u76f8\u5dee\u5f88\u5927\u3002\u6bd4\u8f83\u7ed3\u679c\u65f6\u660e\u786e\u81ea\u5df1\u7684\u771f\u503c\u662f\u7ec6\u80de\u4e2a\u6570\u3001\u8f93\u5165\u8868\u8fbe\u8d21\u732e\uff0c\u8fd8\u662f\u4eba\u4e3a\u5b9a\u4e49\u7684\u5408\u6210\u7cfb\u6570\u3002<\/p>\n

\n\n\n\n\n\n\n\n
\u9a8c\u6536\u4f4d\u7f6e<\/th>\n\u5df2\u77e5\u8f93\u5165<\/th>\n\u4f18\u5148\u68c0\u67e5<\/th>\n<\/tr>\n<\/thead>\n
\u7eaf\u7532\u5bf9\u7167<\/td>\n\u53ea\u542b\u53c2\u8003\u7532\u7c7b\u8c31<\/td>\n\u5176\u4ed6\u4e24\u7c7b\u662f\u5426\u4ecd\u5f97\u5230\u8f83\u5927\u6bd4\u4f8b<\/td>\n<\/tr>\n
\u5df2\u77e5\u6bd4\u4f8b\u7684\u6df7\u5408\u70b9<\/td>\n\u7532\u4e59\u4e19\u6309\u516d\u3001\u4e09\u3001\u4e00\u6df7\u5408<\/td>\n\u4e3b\u5bfc\u7c7b\u578b\u3001\u6bd4\u4f8b\u987a\u5e8f\u3001\u5404\u7c7b\u8bef\u5dee<\/td>\n<\/tr>\n
\u7f3a\u5931\u7c7b\u578b\u5bf9\u7167<\/td>\n\u4ece\u8bad\u7ec3\u53c2\u8003\u91cc\u62ff\u6389\u4e00\u4e2a\u771f\u5b9e\u6765\u6e90<\/td>\n\u6b8b\u5dee\u4e0e\u5269\u4f59\u7c7b\u578b\u6743\u91cd\u600e\u6837\u53d8\u5316<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
\"\u7eaf\u7532\u70b9\u4e3a\u4ec0\u4e48\u8fd8\u6709\u4e59\u3001\u4e19\u3002\u6a21\u62df\u5b9e\u8dd1\uff5c\u516d\u4e2a\u5df2\u77e5\u7ec4\u6210\u7684\u7a7a\u95f4\u70b9\uff0c\u4e09\u4e2a\u7eaf\u7c7b\u578b\u5bf9\u7167\u3002\u7eaf\u7532\uff0c\u7532\u7ea6
\u6a21\u62df\u5b9e\u8dd1\uff5c\u516d\u4e2a\u5df2\u77e5\u7ec4\u6210\u7684\u7a7a\u95f4\u70b9\uff0c\u4e09\u4e2a\u7eaf\u7c7b\u578b\u5bf9\u7167\u3002<\/figcaption><\/figure>\n

\u9664\u4e86\u6bd4\u997c\u56fe\uff0c\u8fd8\u8981\u770b\u54ea\u4e9b\u4f4d\u7f6e\u91cd\u5efa\u5f97\u5dee\u3002\u4f5c\u8005\u7684\u6559\u7a0b\u5c55\u793a\u4e86\u5982\u4f55\u6309\u7a7a\u95f4\u4f4d\u7f6e\u7ed8\u5236\u6b8b\u5dee\u5e73\u65b9\u548c\uff0c\u6355\u6349\u6a21\u578b\u8f83\u96be\u89e3\u91ca\u7684\u533a\u57df\u3002\u628a\u6b8b\u5dee\u4e0e\u6d4b\u5e8f\u6df1\u5ea6\u3001\u7ec4\u7ec7\u8fb9\u7f18\u3001\u574f\u6b7b\u533a\u4ee5\u53ca\u6807\u8bb0\u7f3a\u5931\u7684\u533a\u57df\u5e76\u6392\u753b\uff0c\u624d\u77e5\u9053\u63a5\u4e0b\u6765\u8be5\u67e5\u539f\u59cb\u8ba1\u6570\u3001\u53c2\u8003\u8986\u76d6\uff0c\u8fd8\u662f\u6280\u672f\u566a\u58f0\u3002\u5373\u4f7f\u6b8b\u5dee\u4e0d\u9ad8\uff0c\u4e24\u79cd\u9ad8\u5ea6\u76f8\u4f3c\u7684\u7c7b\u578b\u4e5f\u53ef\u80fd\u4e92\u76f8\u66ff\u4ee3\uff0c\u56e0\u6b64\u5b83\u4e0d\u80fd\u4f5c\u4e3a\u67d0\u7c7b\u7edd\u5bf9\u4e0d\u5b58\u5728\u7684\u8bc1\u636e\u3002\u4e0d\u540c\u9884\u5904\u7406\u6216\u62df\u5408\u5c3a\u5ea6\u4e0b\u7684\u6b8b\u5dee\u503c\u4e5f\u4e0d\u5b9c\u76f4\u63a5\u7528\u540c\u4e00\u6570\u503c\u5b9a\u5408\u683c\u95e8\u69db\u3002\u4f5c\u8005\u7684\u80be\u810f\u6559\u7a0b\u4e0e\u6b8b\u5dee\u56fe<\/a><\/p>\n

\u5b9e\u8dd1\u7ecf\u9a8c\uff5c\u4e09\u4e2a\u7eaf\u70b9\u7684\u6700\u5927\u5206\u91cf\u90fd\u9009\u5bf9\u4e86\uff0c\u4f46\u4ece\u672a\u63a5\u8fd1\u4e00<\/h2>\n

\u6211\u4eec\u5b89\u88c5 SPOTlight 1.14.0\uff0c\u5728 R 4.5.2 \u4e2d\u751f\u6210\u516b\u5341\u56db\u4e2a\u57fa\u56e0\u3001\u516d\u5341\u679a\u53c2\u8003\u7ec6\u80de\uff0c\u7532\u4e59\u4e19\u6bcf\u7c7b\u4e8c\u5341\u679a\u3002\u6bcf\u7c7b\u6709\u4e8c\u5341\u4e2a\u8f83\u9ad8\u8868\u8fbe\u7684\u57fa\u56e0\uff0c\u8bad\u7ec3\u65f6\u4ece\u5404\u81ea\u5217\u8868\u53d6\u5341\u4e94\u4e2a\u8d77\u59cb\u6807\u8bb0\uff0c\u7528\u4e00\u6761\u8ba1\u7b97\u7ebf\u7a0b\uff0c\u8fed\u4ee3\u4e0a\u9650\u4e00\u767e\u3002\u7a7a\u95f4\u70b9\u4e00\u5171\u516d\u4e2a\uff0c\u7531\u53c2\u8003\u7c7b\u578b\u7684\u5e73\u5747\u8c31\u6309\u7ed9\u5b9a\u7cfb\u6570\u6df7\u5408\u3001\u653e\u5927\u5e76\u56db\u820d\u4e94\u5165\u3002\u8fd9\u4e2a\u4f8b\u5b50\u6709\u610f\u8ba9\u6b63\u5bf9\u7167\u6765\u81ea\u76f8\u540c\u53c2\u8003\uff0c\u4f18\u5148\u89c2\u5bdf\u65b9\u6cd5\u5728\u5f53\u524d\u8bbe\u7f6e\u4e0b\u7684\u884c\u4e3a\u3002\u4e3a\u80fd\u68c0\u67e5\u5c0f\u5206\u91cf\uff0c\u6211\u4eec\u5c06\u6700\u4f4e\u4fdd\u7559\u6bd4\u4f8b\u8bbe\u4e3a\u96f6\u3002<\/p>\n

\u5728\u7eaf\u7532\u70b9\u4e0a\uff0c\u9884\u6d4b\u7532\u3001\u4e59\u3001\u4e19\u5206\u522b\u7ea6\u4e3a 0.528\u30010.250 \u548c 0.222\u3002\u7eaf\u4e59\u70b9\u4e2d\u4e59\u7ea6\u4e3a 0.545\uff0c\u7eaf\u4e19\u70b9\u4e2d\u4e19\u7ea6\u4e3a 0.506\u3002\u4e09\u4e2a\u4f4d\u7f6e\u7684\u6700\u5927\u5206\u91cf\u90fd\u7ed9\u4e86\u6b63\u786e\u7c7b\u578b\uff0c\u4f46\u662f\u6ca1\u6709\u4e00\u4e2a\u7eaf\u70b9\u7684\u6b63\u786e\u7c7b\u578b\u63a5\u8fd1\u767e\u5206\u4e4b\u767e\u3002\u516d\u4e2a\u70b9\u3001\u4e09\u4e2a\u7c7b\u578b\u5171\u5341\u516b\u4e2a\u4f30\u8ba1\u4e0e\u8bbe\u5b9a\u6bd4\u4f8b\u76f8\u6bd4\uff0c\u5e73\u5747\u7edd\u5bf9\u8bef\u5dee\u7ea6\u4e3a 0.218\u3002\u8fd9\u91cc\u8861\u91cf\u7684\u662f\u6bd4\u4f8b\u5dee\uff0c\u5982\u628a 0.60 \u4f30\u6210 0.40\uff0c\u5c31\u76f8\u5dee\u4e8c\u5341\u4e2a\u767e\u5206\u70b9\u3002\u8fd9\u4e2a\u7ed3\u679c\u53ea\u5bf9\u5e94\u8fd9\u4efd\u6a21\u62df\u3001\u6807\u8bb0\u548c\u53c2\u6570\uff0c\u63d0\u9192\u6211\u4eec\u5728\u771f\u5b9e\u7ec4\u7ec7\u4e2d\u8ba8\u8bba\u51e0\u4e2a\u767e\u5206\u70b9\u7684\u7a00\u6709\u7fa4\u4e4b\u524d\uff0c\u5148\u770b\u81ea\u5df1\u7684\u7eaf\u5bf9\u7167\u80fd\u628a\u5176\u4ed6\u7c7b\u578b\u538b\u5230\u4ec0\u4e48\u7a0b\u5ea6\u3002<\/p>\n

# fitted \u4e3a SPOTlight() \u7684\u8fd4\u56de\u503c\uff0ctruth \u7684\u884c\u540d\u4e3a\u70b9\u4f4d\u3001\u5217\u540d\u4e3a\u7c7b\u578b\r\npred <- fitted$mat[rownames(truth), colnames(truth), drop = FALSE]\r\nstopifnot(max(abs(rowSums(pred) - 1)) < 1e-4)\r\nabsolute_error <- abs(pred - truth)\r\ncolMeans(absolute_error)\r\n<\/code><\/pre>\n
\u540c\u4e00\u4e2a\u7ed3\u679c\u4e2d\uff0c\u7eaf\u4e19\u70b9\u548c\u540c\u65f6\u542b\u4e09\u79cd\u6765\u6e90\u7684\u70b9\u90fd\u53ef\u80fd\u6709\u4e09\u5757\u989c\u8272\u3002\u628a\u5f88\u5c0f\u7684\u6247\u533a\u7edf\u4e00\u8bbe\u4e3a\u96f6\uff0c\u4f1a\u8ba9\u56fe\u663e\u5f97\u5e72\u51c0\uff0c\u5374\u4e5f\u4f1a\u9690\u53bb\u504f\u5dee\u7684\u6765\u6e90\u3002\u66f4\u597d\u7684\u6392\u67e5\u65b9\u6cd5\u662f\u5148\u770b\u4e24\u4e2a\u6700\u5bb9\u6613\u4e92\u76f8\u5206\u8d70\u6bd4\u4f8b\u7684\u7c7b\u578b\uff0c\u5217\u51fa\u5b83\u4eec\u7684\u6807\u8bb0\u91cd\u53e0\u3001\u5bf9\u5e94\u4e3b\u9898\u548c\u5728\u7eaf\u5bf9\u7167\u4e0a\u7684\u975e\u96f6\u8bef\u5206\u3002\u518d\u79fb\u9664\u5171\u4eab\u6807\u8bb0\u6216\u5408\u5e76\u76f8\u8fd1\u7c7b\u578b\uff0c\u5b8c\u6574\u91cd\u8dd1\u5e76\u6bd4\u8f83\u5df2\u77e5\u6df7\u5408\u7269\u7684\u8bef\u5dee\u3002\u5982\u679c\u53ea\u5728\u56fe\u5f62\u9636\u6bb5\u8c03\u4f4e\u900f\u660e\u5ea6\uff0c\u62df\u5408\u5b9e\u9645\u4e0a\u6ca1\u6709\u6539\u53d8\u3002<\/p>\n
\u56de\u5230\u771f\u5b9e\u5207\u7247\uff0c\u54ea\u4e9b\u70b9\u9002\u5408\u4f18\u5148\u9a8c\u8bc1<\/h2>\n
\u6311\u9009\u771f\u5b9e\u7ec4\u7ec7\u70b9\u65f6\uff0c\u4e00\u7c7b\u9009\u7ec4\u7ec7\u5f62\u6001\u548c\u72ec\u7acb\u6807\u8bb0\u90fd\u652f\u6301\u7684\u76f8\u5bf9\u5355\u7eaf\u533a\u57df\uff0c\u4e00\u7c7b\u9009\u9884\u671f\u591a\u7c7b\u578b\u63a5\u89e6\u7684\u4ea4\u754c\u533a\u3002\u53cc\u65b9\u91c7\u7528\u76f8\u540c\u7684\u5e95\u56fe\u5c3a\u5ea6\u3001\u6700\u5c0f\u663e\u793a\u6bd4\u4f8b\u548c\u539f\u59cb\u8ba1\u6570\u53e3\u5f84\uff0c\u518d\u67e5\u770b\u6a21\u578b\u5728\u5404\u81ea\u533a\u57df\u5bb9\u6613\u628a\u4fe1\u53f7\u5206\u7ed9\u8c01\u3002\u82e5\u201c\u7a00\u6709\u7c7b\u201d\u5728\u6240\u6709\u7eaf\u5bf9\u7167\u91cc\u90fd\u51fa\u73b0\u7ea6\u4e24\u6210\uff0c\u800c\u5728\u80bf\u7624\u8fb9\u7f18\u6070\u597d\u4e5f\u662f\u4e24\u6210\uff0c\u5c31\u9700\u8981\u9ad8\u5206\u8fa8\u7387\u6807\u8bb0\u6216\u72ec\u7acb\u53c2\u8003\u624d\u80fd\u533a\u5206\u771f\u5b9e\u6d78\u6da6\u4e0e\u65b9\u6cd5\u57fa\u7ebf\u3002\u5bf9\u5206\u8fa8\u80fd\u529b\u5b9e\u5728\u4e0d\u8db3\u7684\u4e00\u5bf9\u4e9a\u578b\uff0c\u62a5\u544a\u4e8c\u8005\u5408\u8ba1\u901a\u5e38\u6bd4\u5404\u81ea\u62a5\u4e00\u4e2a\u5c0f\u6570\u70b9\u540e\u4e24\u4f4d\u7684\u6bd4\u4f8b\u66f4\u53ef\u6838\u9a8c\u3002<\/p>\n
\u4fdd\u7559\u53c2\u8003\u7ec6\u80de\u6765\u6e90\u3001\u6807\u8bb0\u6743\u91cd\u3001\u6a21\u578b\u8bbe\u7f6e\u4e0e\u7eaf\u70b9\u9a8c\u6536\u8868\uff0c\u540e\u7eed\u6362\u4e00\u4efd\u53c2\u8003\u65f6\u5373\u53ef\u7528\u76f8\u540c\u95ee\u9898\u68c0\u9a8c\u6539\u8fdb\u3002\u591a\u5207\u7247\u9879\u76ee\u9700\u8981\u91cd\u590d\u8bad\u7ec3\u4e3b\u9898\u3001\u6bd4\u8f83\u591a\u5957\u53c2\u8003\u65f6\uff0c\u53ef\u4e86\u89e3\u4e91\u751f\u4fe1\u7684\u751f\u7269\u4fe1\u606f\u5206\u6790\u670d\u52a1\u5668<\/a>\u3002<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"
\u4ece\u6807\u8bb0\u521d\u59cb\u5316\u5230\u975e\u8d1f\u56de\u5f52\uff0c\u7528\u6a21\u62df\u7eaf\u70b9\u4e0e\u5df2\u77e5\u6df7\u5408\u70b9\u68c0\u9a8c\u53cd\u5377\u79ef\u6bd4\u4f8b\u53ca\u6b8b\u5dee\u3002<\/p>\n","protected":false},"author":1,"featured_media":69446,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[49,72],"tags":[868,853,869],"class_list":["post-69447","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-software","category-transcriptomics","tag-spotlight","tag-853","tag-869"],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2026\/11\/spotlight-nmf-pure-controls-mixture-residuals-guide.png?fit=1200%2C840&ssl=1","_links":{"self":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/69447","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/comments?post=69447"}],"version-history":[{"count":1,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/69447\/revisions"}],"predecessor-version":[{"id":69448,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/69447\/revisions\/69448"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/media\/69446"}],"wp:attachment":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/media?parent=69447"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/categories?post=69447"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/tags?post=69447"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}