{"id":69616,"date":"2026-11-14T21:37:59","date_gmt":"2026-11-14T13:37:59","guid":{"rendered":"https:\/\/www.biocloudservice.com\/wordpress\/?p=69616"},"modified":"2026-11-14T21:37:59","modified_gmt":"2026-11-14T13:37:59","slug":"bayesspace-subspots-parent-grid-cluster-agreement","status":"publish","type":"post","link":"https:\/\/www.biocloudservice.com\/wordpress\/bayesspace-subspots-parent-grid-cluster-agreement\/","title":{"rendered":"BayesSpace \u628a 64 \u4e2a\u70b9\u7ec6\u5206\u6210 256 \u683c\uff0c\u54ea\u4e9b\u53d8\u5316\u80fd\u5199\u8fdb\u7ed3\u679c\uff1f"},"content":{"rendered":"
\n

\u628a\u4e00\u5e45\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u56fe\u653e\u5927\uff0c\u539f\u6765\u4e00\u4e2a\u989c\u8272\u7684\u70b9\u91cc\u51fa\u73b0\u4e24\u79cd\u989c\u8272\uff0c\u4ea4\u754c\u5904\u50cf\u662f\u6d6e\u73b0\u4e86\u4e00\u6761\u7a84\u5e26\u3002\u8981\u5411\u75c5\u7406\u540c\u4e8b\u89e3\u91ca\u8fd9\u5e45\u56fe\uff0c\u9996\u5148\u8981\u77e5\u9053\u7a84\u5e26\u9760\u4ec0\u4e48\u4fe1\u606f\u753b\u51fa\u6765\u3002\u4ece\u7ec4\u7ec7\u5207\u7247\u4e0a\u6355\u83b7\u5206\u5b50\u7684\u4ecd\u662f\u539f\u6765\u7684\u70b9\u4f4d\u3002BayesSpace \u628a\u8fd9\u4e9b\u70b9\u4f4d\u7684\u8868\u8fbe\u964d\u5230\u4f4e\u7ef4\uff0c\u5e76\u8ba9\u90bb\u8fd1\u4f4d\u7f6e\u7684\u5206\u7fa4\u4e92\u76f8\u63d0\u4f9b\u4fe1\u606f\u3002\u7ec6\u5206\u540e\u5f97\u5230\u7684\u662f\u6a21\u578b\u5bf9\u539f\u70b9\u5185\u90e8\u8868\u8fbe\u7ed3\u6784\u7684\u4f30\u8ba1\u3002\u5224\u65ad\u7a84\u5e26\u662f\u5426\u503c\u5f97\u8ffd\u8e2a\uff0c\u53ef\u4ee5\u5206\u5f00\u68c0\u67e5\u539f\u59cb\u70b9\u4f4d\u7684\u8bc1\u636e\u3001\u968f\u673a\u91cd\u590d\u7684\u7a33\u5b9a\u6027\uff0c\u4ee5\u53ca\u7ec4\u7ec7\u56fe\u4e0a\u80fd\u72ec\u7acb\u8fa8\u8ba4\u7684\u7ed3\u6784\u3002BayesSpace \u65b9\u6cd5\u4e0e\u9002\u7528\u6570\u636e<\/a><\/p>\n

\u5148\u628a\u683c\u70b9\u3001\u7167\u7247\u548c\u8868\u8fbe\u77e9\u9635\u5bf9\u9f50<\/h2>\n

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\u5206\u7fa4\u6570\u548c\u7a7a\u95f4\u5e73\u6ed1\u5404\u81ea\u6539\u53d8\u4ec0\u4e48<\/h2>\n

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\n\n\n\n\n\n\n\n
\u770b\u5230\u7684\u7ed3\u679c<\/th>\n\u5bf9\u5e94\u5c42\u7ea7<\/th>\n\u4e0b\u4e00\u6b65\u80fd\u505a\u7684\u68c0\u67e5<\/th>\n<\/tr>\n<\/thead>\n
\u539f\u59cb\u70b9\u4f4d\u5206\u7fa4\u6539\u53d8<\/td>\n\u6bcf\u4e2a\u6355\u83b7\u70b9\u7684\u6a21\u578b\u6807\u7b7e<\/td>\n\u5bf9\u7167\u8d77\u59cb\u5206\u7fa4\u3001\u6d4b\u5e8f\u6df1\u5ea6\u548c\u539f\u59cb\u6807\u8bb0<\/td>\n<\/tr>\n
\u4e00\u4e2a\u539f\u70b9\u5185\u51fa\u73b0\u591a\u79cd\u989c\u8272<\/td>\n\u5b50\u70b9\u7684\u6a21\u578b\u63a8\u65ad<\/td>\n\u56de\u5230\u7236\u70b9\uff0c\u627e\u72ec\u7acb\u5f62\u6001\u6216\u6210\u50cf\u8bc1\u636e<\/td>\n<\/tr>\n
\u589e\u5f3a\u5bf9\u8c61\u53ea\u6709\u4e3b\u6210\u5206<\/td>\n\u5b50\u70b9\u7684\u4f4e\u7ef4\u8868\u793a<\/td>\n\u5206\u6e05\u9ad8\u7ef4\u7279\u5f81\u9884\u6d4b\u4e0e\u5b9e\u9645\u6d4b\u5f97\u7684\u8ba1\u6570<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
\"64
\u65b9\u683c\u6a21\u62df\u5b9e\u8dd1\uff5c\u9010\u683c\u56de\u67e5\u7236\u70b9\uff0c\u518d\u6bd4\u8f83\u4e24\u6b21\u5206\u7fa4\u3002<\/figcaption><\/figure>\n

\u5b9e\u8dd1\u7ecf\u9a8c\uff5c\u5b50\u70b9\u591a\u4e86\u56db\u500d\uff0c\u4e24\u4e2a\u968f\u673a\u8d77\u70b9\u7ed9\u51fa\u600e\u6837\u7684\u5206\u7fa4<\/h2>\n

\u6211\u4eec\u5728 R 4.5.2 \u5b89\u88c5 BayesSpace 1.20.2\uff0c\u7528\u5305\u5185\u793a\u4f8b\u51fd\u6570\u751f\u6210\u516b\u884c\u516b\u5217\u7684\u65b9\u5f62\u9635\u5217\u3001\u516b\u5341\u4e2a\u57fa\u56e0\u548c\u516b\u4e2a\u4e3b\u6210\u5206\u3002\u8be5\u4f8b\u7684\u8868\u8fbe\u662f\u6a21\u62df\u6570\u636e\uff0c\u6ca1\u6709\u4e00\u6761\u5df2\u77e5\u7684\u7ec4\u7ec7\u8fb9\u754c\u4f9b\u6a21\u578b\u6062\u590d\u3002\u56fa\u5b9a\u540c\u4e00\u4e2a\u8f93\u5165\u5bf9\u8c61\uff0c\u8bbe\u4e09\u7c7b\u3001\u53d6\u4e94\u4e2a\u4e3b\u6210\u5206\uff0c\u5206\u522b\u7528\u968f\u673a\u79cd\u5b50\u4e09\u5341\u4e03\u548c\u4e5d\u5341\u4e09\u8fd0\u884c\u7a7a\u95f4\u5206\u7fa4\u3002\u6bcf\u6761\u94fe\u8fd0\u884c\u4e09\u767e\u6b21\u8fed\u4ee3\uff0c\u70e7\u5165\u4e00\u767e\u6b21\u3002\u8fd9\u662f\u6545\u610f\u505a\u77ed\u7684\u6559\u5b66\u8bd5\u9a8c\uff0c\u7528\u6765\u68c0\u67e5\u8f93\u51fa\u5b57\u6bb5\u3001\u968f\u673a\u8d77\u70b9\u548c\u5b50\u70b9\u7d22\u5f15\u3002\u4f5c\u8005\u6559\u7a0b\u4e2d\u7ed9\u5b9e\u9645\u5206\u6790\u7684\u8fed\u4ee3\u5efa\u8bae\u8fdc\u9ad8\u4e8e\u8fd9\u91cc\u7684\u8bbe\u7f6e\uff0c\u5207\u7247\u5206\u6790\u5e94\u8fdb\u4e00\u6b65\u68c0\u67e5\u591a\u6761\u94fe\u7684\u8868\u73b0\u3002\u6559\u7a0b\u4e2d\u7684\u8fed\u4ee3\u8bbe\u7f6e\u548c\u6536\u655b\u68c0\u67e5<\/a><\/p>\n

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# one \u548c two \u4e3a\u4e24\u6b21 spatialCluster \u7684\u8f93\u51fa\uff0chi \u4e3a spatialEnhance \u7684\u8f93\u51fa\r\na <- one$spatial.cluster\r\nb <- two$spatial.cluster\r\nstopifnot(identical(colnames(one), colnames(two)))\r\nmclust::adjustedRandIndex(a, b)\r\ntable(table(hi$spot.idx))\r\ndim(SingleCellExperiment::reducedDim(hi, "PCA"))\r\nSummarizedExperiment::assayNames(hi)\r\n<\/code><\/pre>\n
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\u540c\u4e8b\u62ff\u5230\u56fe\u540e\u5e94\u5f53\u80fd\u591f\u56de\u5230\u54ea\u4e00\u6b65<\/h2>\n
\u63d0\u4ea4\u7ed3\u679c\u65f6\uff0c\u53ef\u4ee5\u5728\u4e00\u4e2a\u7a84\u8fb9\u754c\u548c\u4e00\u4e2a\u5747\u5300\u5185\u90e8\u533a\u5404\u9009\u51e0\u679a\u7236\u70b9\uff0c\u7ed9\u51fa\u7236\u70b9\u6761\u5f62\u7801\u3001\u539f\u59cb\u6807\u8bb0\u5206\u5b50\u6570\u3001\u4e24\u6761\u94fe\u7684\u7236\u70b9\u6807\u7b7e\u4ee5\u53ca\u5b50\u70b9\u5f52\u5c5e\u3002\u8fb9\u754c\u9644\u8fd1\u82e5\u51fa\u73b0\u7a33\u5b9a\u5206\u5272\uff0c\u4e14\u72ec\u7acb\u6210\u50cf\u6355\u6349\u5230\u76f8\u90bb\u4e24\u4fa7\u4e0d\u540c\u7684\u6807\u8bb0\u7ec4\u5408\uff0c\u5c31\u6709\u7406\u7531\u5b89\u6392\u66f4\u7cbe\u7ec6\u7684\u9a8c\u8bc1\u3002\u82e5\u5355\u6b21\u4e3b\u56fe\u5f88\u6e05\u695a\uff0c\u4f46\u6362\u968f\u673a\u8d77\u70b9\u540e\u4ea4\u754c\u4f4d\u7f6e\u5927\u5e45\u53d8\u5316\uff0c\u4fdd\u7559\u539f\u70b9\u5c3a\u5ea6\u6765\u9648\u8ff0\u53d1\u73b0\u4f1a\u66f4\u5408\u9002\u3002\u4e00\u5f20\u5c0f\u8303\u56f4\u653e\u5927\u56fe\u914d\u4e0a\u8fd9\u4e9b\u7236\u70b9\u8bb0\u5f55\uff0c\u6bd4\u4ec5\u5bfc\u51fa\u4e00\u5e45\u66f4\u5bc6\u7684\u5f69\u8272\u6563\u70b9\u56fe\u66f4\u4fbf\u4e8e\u540c\u884c\u590d\u6838\u3002<\/p>\n
\u591a\u5f20\u5207\u7247\u9700\u8981\u6bd4\u8f83\u5206\u7fa4\u6570\u3001\u968f\u673a\u8d77\u70b9\u548c\u8fed\u4ee3\u957f\u5ea6\u65f6\uff0c\u53ef\u4ee5\u5148\u7528\u4e00\u5f20\u4ee3\u8868\u6027\u5207\u7247\u786e\u5b9a\u68c0\u67e5\u65b9\u5f0f\uff0c\u518d\u5b89\u6392\u6574\u6279\u8fd0\u884c\u3002\u9700\u8981\u4fdd\u5b58\u5404\u6761\u94fe\u548c\u4e2d\u95f4\u5bf9\u8c61\u7684\u7814\u7a76\u56e2\u961f\uff0c\u53ef\u4e86\u89e3\u4e91\u751f\u4fe1\u7684\u751f\u7269\u4fe1\u606f\u5206\u6790\u670d\u52a1\u5668<\/a>\u3002<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"
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