{"id":71413,"date":"2026-11-15T00:50:00","date_gmt":"2026-11-14T16:50:00","guid":{"rendered":"https:\/\/www.biocloudservice.com\/wordpress\/?p=71413"},"modified":"2026-11-15T01:14:55","modified_gmt":"2026-11-14T17:14:55","slug":"whatshap-phasing-depth-unchanged-read-bridges-phase-sets","status":"publish","type":"post","link":"https:\/\/www.biocloudservice.com\/wordpress\/whatshap-phasing-depth-unchanged-read-bridges-phase-sets\/","title":{"rendered":"WhatsHap \u5b9e\u8dd1\uff5c\u56db\u4e2a\u4f4d\u70b9\u90fd\u662f\u6742\u5408\uff0c\u9010\u78b1\u57fa\u6df1\u5ea6\u4e5f\u76f8\u540c\uff0c\u4e3a\u4ec0\u4e48\u4f1a\u5206\u6210\u4e24\u4e2a\u76f8\u4f4d\u5757\uff1f"},"content":{"rendered":"<div class=\"ysx-method-guide\" style=\"max-width:820px;min-width:0;margin:0 auto;color:#26374a;line-height:1.86;overflow-wrap:anywhere\">\n<p>\u4e24\u4e2a\u53d8\u5f02\u51fa\u73b0\u5728\u540c\u4e00\u6761\u67d3\u8272\u4f53\u62f7\u8d1d\u4e0a\uff0c\u548c\u5b83\u4eec\u5404\u5728\u4e00\u6761\u62f7\u8d1d\u4e0a\uff0c\u53ef\u80fd\u5bf9\u5e94\u5b8c\u5168\u4e0d\u540c\u7684\u540e\u7eed\u9a8c\u8bc1\u5b9e\u9a8c\u3002\u5355\u770b\u6bcf\u4e2a\u4f4d\u70b9\u7684\u6742\u5408\u57fa\u56e0\u578b\uff0c\u65e0\u6cd5\u544a\u8bc9\u6211\u4eec\u662f\u54ea\u79cd\u7ec4\u5408\u3002\u66f4\u5bb9\u6613\u88ab\u6f0f\u6389\u7684\u662f\uff0c\u5206\u76f8\u540e\u7684\u6587\u4ef6\u91cc\uff0c\u5373\u4f7f\u6bcf\u4e2a\u4f4d\u70b9\u90fd\u5e26\u7ad6\u7ebf\uff0c\u4e5f\u53ef\u80fd\u53ea\u6709\u90e8\u5206\u53d8\u5f02\u4e4b\u95f4\u7684\u4f4d\u7f6e\u5173\u7cfb\u5f97\u5230\u8bfb\u6bb5\u652f\u6301\u3002\u6211\u4eec\u7528\u5b8c\u5168\u76f8\u540c\u7684\u78b1\u57fa\u548c\u9010\u4f4d\u7f6e\u6df1\u5ea6\u505a\u4e86\u4e24\u4efd\u8f93\u5165\uff0c\u53ea\u6539\u53d8\u4e2d\u95f4\u51e0\u6761\u8bfb\u6bb5\u662f\u4e0d\u662f\u540c\u4e00\u6761\u8fde\u7eed\u5206\u5b50\uff0c\u518d\u7528 WhatsHap \u5b9e\u9645\u5206\u76f8\u3002<a style=\"color:#5954a2;text-decoration:underline;text-underline-offset:2px\" href=\"https:\/\/whatshap.readthedocs.io\/en\/latest\/guide.html\">WhatsHap \u5b98\u65b9\u4f7f\u7528\u6307\u5357<\/a><\/p>\n<h2 style=\"font-size:1.38em;line-height:1.5;margin:1.55em 0 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style=\"color:#5954a2;text-decoration:underline;text-underline-offset:2px\" href=\"https:\/\/whatshap.readthedocs.io\/en\/latest\/\">\u4f5c\u8005\u7684\u8bfb\u6bb5\u5206\u76f8\u65b9\u6cd5\u4e0e\u6559\u7a0b<\/a><\/p>\n<h2 style=\"font-size:1.38em;line-height:1.5;margin:1.55em 0 .55em;color:#182d43\">\u5b9e\u8dd1\u7ecf\u9a8c\uff5c\u53ea\u526a\u5f00\u8d1f\u8d23\u8de8\u533a\u7684\u516b\u6761\u8bfb\u6bb5<\/h2>\n<p>\u6211\u4eec\u9020\u4e86\u4e00\u6761\u4e09\u5343\u78b1\u57fa\u7684\u53c2\u8003\u5e8f\u5217\uff0c\u8bbe\u7f6e\u56db\u4e2a\u5df2\u77e5\u6742\u5408\u4f4d\u70b9\uff0c\u5750\u6807\u4ece\u4e00\u5f00\u59cb\u8ba1\u6570\uff0c\u5206\u522b\u4e3a 501\u3001901\u30012101 \u548c 2501\u3002\u4e24\u6761\u5355\u500d\u578b\u5728\u6bcf\u4e2a\u4f4d\u70b9\u5404\u643a\u5e26\u4e00\u4e2a\u7b49\u4f4d\u3002\u5de6\u4fa7\u8bfb\u6bb5\u8986\u76d6\u524d\u4e24\u4e2a\u4f4d\u7f6e\uff0c\u53f3\u4fa7\u8bfb\u6bb5\u8986\u76d6\u540e\u4e24\u4e2a\u4f4d\u7f6e\uff0c\u53e6\u6709\u516b\u6761\u4e2d\u95f4\u8bfb\u6bb5\u540c\u65f6\u7ecf\u8fc7\u4e24\u4e2a\u5185\u4fa7\u4f4d\u7f6e\u3002\u7b2c\u4e00\u7ec4\u4fdd\u7559\u5b8c\u6574\u5206\u5b50\u3002\u7b2c\u4e8c\u7ec4\u628a\u8fd9\u516b\u6761\u5404\u526a\u6210\u4e24\u6bb5\uff0c\u5de6\u53f3\u7247\u6bb5\u4f7f\u7528\u4e0d\u540c\u8bfb\u6bb5\u540d\uff0c\u4ecd\u5728\u539f\u6765\u7684\u4f4d\u7f6e\u6bd4\u5bf9\uff0c\u6ca1\u6709\u5220\u6389\u6216\u589e\u52a0\u4efb\u4f55\u4e00\u4e2a\u78b1\u57fa\u3002\u8fd0\u884c\u7248\u672c\u4e3a WhatsHap 2.8\uff0c\u4f7f\u7528\u540c\u4e00\u4e2a\u53c2\u8003\u6587\u4ef6\u548c\u672a\u5206\u76f8\u53d8\u5f02\u8868\u3002<\/p>\n<div class=\"guide-table\" style=\"max-width:100%;overflow-x:auto;margin:18px 0\">\n<table style=\"display:table;width:100%;max-width:100%;min-width:0;table-layout:fixed;border-collapse:collapse;font-size:.92em;line-height:1.6\">\n<thead>\n<tr>\n<th scope=\"col\" style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;background:#f2efff;color:#1e293b;vertical-align:top;text-align:left;padding:6px;border:1px solid #c4cfdb\">\u68c0\u67e5\u9879<\/th>\n<th scope=\"col\" style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;background:#f2efff;color:#1e293b;vertical-align:top;text-align:left;padding:6px;border:1px solid #c4cfdb\">\u8de8\u533a\u8bfb\u6bb5\u5b8c\u6574<\/th>\n<th scope=\"col\" style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;background:#f2efff;color:#1e293b;vertical-align:top;text-align:left;padding:6px;border:1px solid #c4cfdb\">\u516b\u6761\u8de8\u533a\u8bfb\u6bb5\u526a\u5f00<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">\u6bd4\u5bf9\u8bb0\u5f55\u4e0e\u5bf9\u9f50\u78b1\u57fa\u603b\u6570<\/td>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">28 \u6761\uff0c26700 bp<\/td>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">36 \u6761\uff0c26700 bp<\/td>\n<\/tr>\n<tr>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">\u56db\u4e2a\u4f4d\u70b9\u7684\u53c2\u8003 \/ \u66ff\u4ee3\u8bfb\u6bb5\u6570<\/td>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">5\/5\u30019\/9\u30019\/9\u30015\/5<\/td>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">5\/5\u30019\/9\u30019\/9\u30015\/5<\/td>\n<\/tr>\n<tr>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">\u5206\u76f8\u4f4d\u70b9\u6570<\/td>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">4 \/ 4<\/td>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">4 \/ 4<\/td>\n<\/tr>\n<tr>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">\u76f8\u4f4d\u5757\u9996\u672b\u4f4d\u70b9<\/td>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">501\u20132501<\/td>\n<td style=\"white-space:normal;overflow-wrap:anywhere;word-break:normal;padding:6px;vertical-align:top;border:1px solid #c4cfdb\">501\u2013901 \u548c 2101\u20132501<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>\u6211\u4eec\u8fd8\u7528\u7a0b\u5e8f\u9010\u4e2a\u6bd4\u8f83\u53c2\u8003\u4e0a\u4e09\u5343\u4e2a\u4f4d\u7f6e\u7684\u6df1\u5ea6\uff0c\u5168\u90e8\u4e00\u81f4\u3002\u5b8c\u6574\u7ec4\u7684\u56db\u4e2a\u4f4d\u7f6e\u5171\u4eab\u540c\u4e00\u4e2a\u76f8\u4f4d\u7ec4\u7f16\u53f7\uff0c\u526a\u5f00\u7ec4\u7684\u540e\u4e24\u4e2a\u4f4d\u7f6e\u83b7\u5f97\u4e86\u53e6\u4e00\u4e2a\u7f16\u53f7\u3002\u539f\u56e0\u53ef\u4ee5\u76f4\u63a5\u5728\u6bd4\u5bf9\u91cc\u627e\u5230\uff0c\u4e2d\u95f4\u7684\u4e24\u4e2a\u4f4d\u7f6e\u4ecd\u5404\u6709\u4e5d\u6761\u53c2\u8003\u652f\u6301\u548c\u4e5d\u6761\u66ff\u4ee3\u652f\u6301\uff0c\u4f46\u526a\u5f00\u540e\u6ca1\u6709\u4e00\u6761\u5206\u5b50\u540c\u65f6\u4e3a\u4e24\u4e2a\u4f4d\u7f6e\u4f5c\u8bc1\u3002\u7531\u6b64\u53ef\u89c1\uff0c\u5373\u4f7f\u201c\u5206\u76f8\u6bd4\u4f8b\u201d\u4e00\u680f\u4e24\u8fb9\u90fd\u5199\u767e\u5206\u4e4b\u767e\uff0c\u5b83\u4e5f\u65e0\u6cd5\u66ff\u4ee3\u201c\u5173\u5fc3\u7684\u4e24\u4e2a\u53d8\u5f02\u662f\u5426\u540c\u5757\u201d\u8fd9\u4e2a\u95ee\u9898\u3002<\/p>\n<figure class=\"guide-figure\" style=\"margin:24px 0 28px\"><img loading=\"lazy\" decoding=\"async\" src=\"\/wordpress\/wp-content\/uploads\/2026\/11\/whatshap-phasing-depth-unchanged-read-bridges-phase-sets-guide.png\" alt=\"\u76f8\u540c\u7684\u6df1\u5ea6\uff0c\u4e0d\u540c\u7684\u76f8\u4f4d\u5757\u3002\u526a\u5f00\u8fde\u63a5\u4e2d\u95f4\u4e24\u4e2a\u4f4d\u70b9\u7684\u516b\u6761\u5206\u5b50\uff0c\u6240\u6709\u4f4d\u7f6e\u7684\u6df1\u5ea6\u4e0d\u53d8\u3002\u8fde\u5728\u4e00\u8d77\uff0c\u56db\u4e2a\u4f4d\u70b9\u5171\u4eab\u540c\u4e00\u4e2a PS\uff0c\u540c\u4e00\u76f8\u4f4d\u5757\u4ece 501 \u5ef6\u4f38\u81f3 2501\u3002\u526a\u6210\u4e24\u6bb5\uff0c\u56db\u4e2a\u4f4d\u70b9\u5206\u522b\u5f52\u5165\u4e24\u4e2a PS\uff0c\u4e24\u4e2a\u5757\u5404\u542b\u4e24\u4e2a\u53ef\u5206\u76f8\u7684\u6742\u5408\u4f4d\u70b9\u3002\u67e5\u770b\u5224\u65ad\uff0c\u540c\u4e00\u6837\u672c\u3001\u540c\u4e00\u67d3\u8272\u4f53\u3001\u540c\u4e00\u5757\uff0c\u8de8\u5757\u7684\u4e24\u5217\u5404\u81ea\u53ef\u4ee5\u72ec\u7acb\u4ea4\u6362\u3002\" width=\"1200\" height=\"840\" style=\"display:block;width:100%;height:auto;border-radius:10px\"><figcaption style=\"font-size:14px;line-height:1.6;margin:9px 2px 0;color:#475569\">\u526a\u5f00\u8fde\u63a5\u4e2d\u95f4\u4e24\u4e2a\u4f4d\u70b9\u7684\u516b\u6761\u5206\u5b50\uff0c\u6240\u6709\u4f4d\u7f6e\u7684\u6df1\u5ea6\u4e0d\u53d8\u3002<\/figcaption><\/figure>\n<h2 style=\"font-size:1.38em;line-height:1.5;margin:1.55em 0 .55em;color:#182d43\">\u8bfb\u61c2\u7ad6\u7ebf\u65c1\u8fb9\u7684\u76f8\u4f4d\u7ec4\u7f16\u53f7<\/h2>\n<p>\u5728\u5b8c\u6574\u7ec4\uff0c\u524d\u4e24\u4e2a\u4f4d\u70b9\u4f9d\u6b21\u4e3a <code>1|0<\/code> \u548c <code>0|1<\/code>\u3002\u5728\u526a\u5f00\u7ec4\uff0c\u8fd9\u4e24\u4e2a\u4f4d\u7f6e\u7684\u5199\u6cd5\u4e00\u8d77\u7ffb\u8f6c\u6210 <code>0|1<\/code> \u548c <code>1|0<\/code>\u3002\u4e4d\u770b\u50cf\u662f\u7ed3\u8bba\u53cd\u8fc7\u6765\u4e86\uff0c\u5176\u5b9e\u5b83\u4eec\u5185\u90e8\u4ecd\u7136\u662f\u76f8\u5bf9\u7684\uff0c\u4e24\u5904\u66ff\u4ee3\u7b49\u4f4d\u4ecd\u4f4d\u4e8e\u4e0d\u540c\u62f7\u8d1d\u3002\u53ea\u51ed\u5355\u4e2a\u4e2a\u4f53\u7684\u8bfb\u6bb5\uff0c\u7b97\u6cd5\u901a\u5e38\u65e0\u6cd5\u7ed9\u8f93\u51fa\u7684\u7b2c\u4e00\u5217\u547d\u540d\u4e3a\u7236\u6e90\u6216\u6bcd\u6e90\u3002\u540c\u4e00\u5757\u4e2d\u6240\u6709\u4f4d\u70b9\u7684\u4e24\u5217\u4e00\u8d77\u4ea4\u6362\uff0c\u4ecd\u8868\u8fbe\u76f8\u540c\u7684\u76f8\u5bf9\u7ec4\u5408\u3002\u771f\u6b63\u9700\u8981\u62c5\u5fc3\u7684\u662f\u53ea\u7ffb\u8f6c\u67d0\u4e00\u6bb5\uff0c\u6539\u53d8\u4e86\u540c\u4e00\u5757\u5185\u90e8\u6709\u8bc1\u636e\u7684\u76f8\u90bb\u5173\u7cfb\u3002<\/p>\n<p>\u6362\u5230\u4e0d\u540c\u76f8\u4f4d\u5757\uff0c\u5757\u7684\u5de6\u53f3\u65b9\u5411\u53ef\u4ee5\u5404\u81ea\u72ec\u7acb\u7ffb\u8f6c\u3002\u526a\u5f00\u7ec4\u7684\u7b2c\u4e00\u548c\u7b2c\u56db\u4e2a\u4f4d\u70b9\u6070\u597d\u4e5f\u586b\u5199\u4e86\u4e24\u5217\u6570\u5b57\uff0c\u4f46\u8fd9\u65f6\u6bd4\u8f83\u4e24\u884c\u7684\u7b2c\u4e00\u5217\u5df2\u7ecf\u8d8a\u8fc7\u8bc1\u636e\u8fb9\u754c\u3002\u5728\u771f\u5b9e\u9879\u76ee\u91cc\u7ed9\u51fa\u987a\u5f0f\u6216\u53cd\u5f0f\u5224\u65ad\u65f6\uff0c\u5e94\u540c\u65f6\u62a5\u544a\u6837\u672c\u3001\u67d3\u8272\u4f53\u3001\u76f8\u4f4d\u7ec4\u7f16\u53f7\u3001\u76ee\u6807\u5750\u6807\u548c\u652f\u6301\u7684\u8bfb\u6bb5\u3002\u5982\u679c\u4e24\u4e2a\u76ee\u6807\u8de8\u5757\uff0c\u53ea\u80fd\u8bb0\u5f55\u4e3a\u8fd9\u6279\u8bfb\u6bb5\u672a\u786e\u5b9a\u76f8\u5bf9\u5173\u7cfb\u3002\u53ef\u4ee5\u518d\u627e\u66f4\u957f\u7684\u5206\u5b50\u3001\u5bb6\u7cfb\u4fe1\u606f\u6216\u5176\u4ed6\u72ec\u7acb\u8bc1\u636e\uff0c\u800c\u4e0d\u80fd\u7528\u6587\u672c\u5217\u7684\u6392\u5217\u5ef6\u957f\u8bc1\u636e\u8303\u56f4\u3002<\/p>\n<pre style=\"max-width:100%;box-sizing:border-box;overflow-x:auto;margin:18px 0;padding:14px 16px;background:#f3f6fa;color:#1a293c;border:1px solid #d8e1ea;border-radius:8px;line-height:1.55;white-space:pre;overflow-wrap:normal;word-break:normal\"><code class=\"language-bash\">whatshap phase --reference ref.fa -o phased.vcf input.vcf example.bam\r\nwhatshap stats --block-list blocks.tsv --tsv stats.tsv phased.vcf\r\nbcftools query -s S -f '%CHROM\\t%POS[\\t%GT\\t%PS]\\n' phased.vcf\r\n<\/code><\/pre>\n<h2 style=\"font-size:1.38em;line-height:1.5;margin:1.55em 0 .55em;color:#182d43\">\u5728\u81ea\u5df1\u7684\u4f4d\u70b9\u4e0a\u600e\u6837\u6392\u67e5<\/h2>\n<p>\u5148\u628a\u611f\u5174\u8da3\u7684\u4e24\u4e2a\u4f4d\u7f6e\u4ece\u8f93\u51fa\u6587\u4ef6\u4e2d\u9010\u4e2a\u53d6\u51fa\uff0c\u6838\u5bf9\u5b83\u4eec\u662f\u540c\u4e00\u6837\u672c\u3001\u540c\u4e00\u67d3\u8272\u4f53\u4e0a\u7684\u6742\u5408\u8c03\u7528\uff0c\u7136\u540e\u6bd4\u5bf9\u76f8\u4f4d\u7ec4\u5b57\u6bb5\u3002\u9047\u5230\u4e2d\u9014\u65ad\u5757\uff0c\u53ef\u4ee5\u4ece\u6700\u540e\u4e00\u4e2a\u6709\u8fde\u63a5\u8bc1\u636e\u7684\u6742\u5408\u4f4d\u70b9\u5411\u5916\u770b\uff0c\u8bb0\u5f55\u8de8\u8fc7\u5b83\u548c\u4e0b\u4e00\u4e2a\u5408\u683c\u4f4d\u70b9\u7684\u5206\u5b50\u6570\u3002\u68c0\u67e5\u8fd9\u4e9b\u5206\u5b50\u662f\u5426\u5728\u4e24\u4e2a\u4f4d\u70b9\u90fd\u5177\u5907\u8db3\u591f\u78b1\u57fa\u8d28\u91cf\uff0c\u662f\u5426\u5728\u91cd\u590d\u533a\u6709\u591a\u5904\u76f8\u4f3c\u6bd4\u5bf9\uff0c\u662f\u5426\u53ea\u662f\u5728\u5750\u6807\u4e0a\u6a2a\u8de8\u5374\u7528\u5220\u9664\u64cd\u4f5c\u8df3\u8fc7\u4e86\u5173\u952e\u78b1\u57fa\u3002\u628a\u80fd\u8bfb\u51fa\u4e24\u7aef\u7ec4\u5408\u7684\u5206\u5b50\u5217\u51fa\u6765\uff0c\u6bd4\u628a\u67d0\u4e2a\u4f4d\u7f6e\u7684\u603b\u6df1\u5ea6\u8bb0\u5f97\u66f4\u7cbe\u786e\u3002<\/p>\n<p>\u5982\u679c\u9879\u76ee\u6700\u7ec8\u8981\u6bd4\u8f83\u4e24\u4e2a\u65b9\u6848\uff0c\u9664\u4e86\u6bcf\u4e2a\u4f4d\u70b9\u7684\u5206\u76f8\u6bd4\u4f8b\uff0c\u8fd8\u5e94\u62a5\u544a\u6bcf\u4e2a\u76f8\u4f4d\u5757\u5305\u542b\u591a\u5c11\u4e2a\u6742\u5408\u4f4d\u70b9\u3001\u4ece\u54ea\u4e2a\u5750\u6807\u5ef6\u4f38\u5230\u54ea\u91cc\uff0c\u4ee5\u53ca\u76ee\u6807\u57fa\u56e0\u4e2d\u6709\u591a\u5c11\u5bf9\u4f4d\u70b9\u843d\u5728\u540c\u4e00\u5757\u3002\u76f8\u4f4d\u5757\u8de8\u5ea6\u5f88\u5927\u65f6\uff0c\u4e2d\u95f4\u53ef\u80fd\u6709\u5f88\u957f\u4e00\u6bb5\u6ca1\u6709\u4fe1\u606f\u7684\u5e8f\u5217\uff0c\u4e24\u4e2a\u7aef\u70b9\u4e4b\u95f4\u4e5f\u672a\u5fc5\u7531\u4e00\u6761\u5355\u72ec\u5206\u5b50\u76f4\u63a5\u8de8\u8d8a\u3002\u8981\u68c0\u9a8c\u5206\u76f8\u662f\u5426\u6b63\u786e\uff0c\u8fd8\u9700\u8981\u53ef\u4fe1\u771f\u503c\u6216\u72ec\u7acb\u6750\u6599\uff0c\u6309\u5404\u5757\u76f8\u5bf9\u65b9\u5411\u53ef\u4ea4\u6362\u7684\u539f\u5219\u8ba1\u7b97\u5207\u6362\u9519\u8bef\u3002\u4ee5\u4e0a\u8fd9\u6b21\u4eba\u5de5\u5bf9\u7167\u9a8c\u8bc1\u7684\u662f\u8fde\u7eed\u5206\u5b50\u5bf9\u6210\u5757\u7684\u4f5c\u7528\uff0c\u9002\u5408\u7528\u6765\u68c0\u67e5\u7edf\u8ba1\u53e3\u5f84\u3002<a style=\"color:#5954a2;text-decoration:underline;text-underline-offset:2px\" href=\"https:\/\/whatshap.readthedocs.io\/en\/latest\/guide.html#phasing-statistics\">WhatsHap \u76f8\u4f4d\u5757\u7edf\u8ba1\u4e0e\u6bd4\u8f83<\/a><\/p>\n<p><a style=\"color:#5954a2;text-decoration:underline;text-underline-offset:2px\" href=\"https:\/\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2026\/11\/ysx-bioinformatics-practice-074-085-b0103eb15d21.zip\">\u4e0b\u8f7d\u672c\u7bc7\u5b9e\u9a8c\u811a\u672c\u4e0e\u7ed3\u679c\uff0812 \u7bc7\u5408\u96c6 ZIP\uff09<\/a>\uff0c\u89e3\u538b\u540e\u6253\u5f00 <code>079-whatshap<\/code> \u76ee\u5f55\u3002<\/p>\n<p class=\"guide-end\" style=\"margin-top:1.6em;padding-top:1.0em;border-top:1px solid #d7e0e9\">\u9700\u8981\u5bf9\u4e00\u6279\u957f\u8bfb\u957f\u6837\u672c\u53cd\u590d\u6838\u5bf9\u76ee\u6807\u4f4d\u70b9\u53ca\u5176\u8de8\u8d8a\u8bfb\u6bb5\u65f6\uff0c\u53ef\u4ee5\u5728<a data-ysx-event=\"contact_click\" style=\"color:#5954a2;text-decoration:underline;text-underline-offset:2px\" href=\"https:\/\/www.biocloudservice.com\/wordpress\/compute-services\/shared-research-workspace\/\">\u4e91\u751f\u4fe1\u7684\u751f\u7269\u4fe1\u606f\u5206\u6790\u670d\u52a1\u5668<\/a>\u628a\u6bd4\u5bf9\u3001\u53c2\u8003\u548c\u5206\u76f8\u7248\u672c\u4fdd\u5b58\u5728\u540c\u4e00\u5206\u6790\u76ee\u5f55\u3002<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u4fdd\u6301\u6240\u6709\u78b1\u57fa\u548c\u9010\u4f4d\u70b9\u6df1\u5ea6\u76f8\u540c\uff0c\u68c0\u9a8c\u5206\u76f8\u6bd4\u4f8b\u3001PS \u7f16\u53f7\u548c\u8de8\u4f4d\u70b9\u8bc1\u636e\u5206\u522b\u544a\u8bc9\u6211\u4eec\u4ec0\u4e48\u3002<\/p>\n","protected":false},"author":1,"featured_media":71412,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[49],"tags":[1088,1089,595,416],"class_list":["post-71413","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-software","tag-whatshap","tag-1089","tag-595","tag-416"],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2026\/11\/whatshap-phasing-depth-unchanged-read-bridges-phase-sets-guide.png?fit=1200%2C840&ssl=1","_links":{"self":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/71413","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/comments?post=71413"}],"version-history":[{"count":2,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/71413\/revisions"}],"predecessor-version":[{"id":71534,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/71413\/revisions\/71534"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/media\/71412"}],"wp:attachment":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/media?parent=71413"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/categories?post=71413"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/tags?post=71413"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}