{"id":73093,"date":"2026-11-15T13:42:50","date_gmt":"2026-11-15T05:42:50","guid":{"rendered":"https:\/\/www.biocloudservice.com\/wordpress\/?p=73093"},"modified":"2026-11-15T13:42:50","modified_gmt":"2026-11-15T05:42:50","slug":"transdecoder7-orf-complete-ranking-strand-preset-practice","status":"publish","type":"post","link":"https:\/\/www.biocloudservice.com\/wordpress\/transdecoder7-orf-complete-ranking-strand-preset-practice\/","title":{"rendered":"TransDecoder 7 \u5b9e\u8dd1\uff0c\u5b8c\u6574 ORF\u3001\u6700\u957f ORF \u548c\u771f\u5b9e\u5b8c\u6574\u86cb\u767d\u4e0d\u662f\u540c\u4e00\u56de\u4e8b"},"content":{"rendered":"
\n

\u8f6c\u5f55\u672c\u7ec4\u88c5\u7ed3\u675f\u540e\uff0c\u5e38\u89c1\u7684\u4e0b\u4e00\u6b65\u662f\u9884\u6d4b\u5f00\u653e\u9605\u8bfb\u6846\u3002\u7ed3\u679c\u6587\u4ef6\u91cc\u51fa\u73b0\u4e00\u4e2a\u5b8c\u6574\u6807\u8bb0\uff0c\u662f\u5426\u5c31\u80fd\u8ba4\u5b9a\u5f97\u5230\u4e86\u5b8c\u6574\u86cb\u767d\uff1f\u4e00\u6761\u8f6c\u5f55\u672c\u4e0a\u5b58\u5728\u4e24\u4e2a\u8f83\u957f\u5f00\u653e\u9605\u8bfb\u6846\uff0c\u662f\u5426\u603b\u4f1a\u4fdd\u7559\u66f4\u957f\u7684\u90a3\u4e2a\uff1f\u8fd9\u4e9b\u95ee\u9898\u4e0d\u80fd\u53ea\u9760\u8f93\u51fa\u540d\u79f0\u56de\u7b54\uff0c\u9700\u8981\u628a\u5019\u9009\u63d0\u53d6\u3001\u7f16\u7801\u8bc1\u636e\u7b5b\u9009\u548c\u6700\u7ec8\u62a5\u544a\u89c4\u5219\u5206\u5f00\u770b\u3002<\/p>\n

\u672c\u7bc7\u5b9e\u9645\u5b89\u88c5\u5e76\u8fd0\u884c TransDecoder \u4e03\u70b9\u96f6\u70b9\u96f6\uff0c\u4f7f\u7528\u4e24\u6761\u6709\u56fa\u5b9a\u7248\u672c\u7684\u516c\u5171\u4eba\u7c7b\u8f6c\u5f55\u672c\uff0c\u518d\u6784\u9020\u622a\u77ed\u3001\u53cd\u5411\u4e92\u8865\u548c\u53cc\u9605\u8bfb\u6846\u8f93\u5165\uff0c\u5b8c\u6210\u56db\u7ec4\u5bf9\u7167\u3002\u91cd\u70b9\u662f\u7406\u89e3\u5de5\u5177\u5982\u4f55\u7b5b\u9009\u5019\u9009\uff0c\u4ee5\u53ca\u54ea\u4e9b\u7ed3\u679c\u4e0d\u80fd\u76f4\u63a5\u4e0a\u5347\u4e3a\u751f\u7269\u5b66\u7ed3\u8bba\u3002\u4eba\u5de5\u884d\u751f\u5e8f\u5217\u4ec5\u7528\u4e8e\u6d4b\u8bd5\u89c4\u5219\uff0c\u4e0d\u4ee3\u8868\u53d1\u73b0\u4e86\u65b0\u7684\u526a\u63a5\u4f53\u3001\u878d\u5408\u8f6c\u5f55\u672c\u6216\u77ed\u80bd\u3002<\/p>\n

\"\u5b8c\u6574\u6807\u7b7e\uff0c\u4e0d\u4fdd\u8bc1\u86cb\u767d\u6ca1\u6709\u622a\u77ed\u3002TransDecoder
TransDecoder 7 \u5b9e\u8dd1\u56db\u7ec4\u7b5b\u9009\u89c4\u5219<\/figcaption><\/figure>\n

\u5148\u6838\u5bf9\u7248\u672c\uff0c\u65e7\u6559\u7a0b\u7684\u9ed8\u8ba4\u884c\u4e3a\u5df2\u7ecf\u6539\u53d8<\/h2>\n

\u4e03\u70b9\u96f6\u70b9\u96f6\u4e8e\u4e8c\u3007\u4e8c\u516d\u5e74\u5341\u4e00\u6708\u4e8c\u65e5\u53d1\u5e03\uff0c\u8c03\u6574\u4e86\u5019\u9009\u957f\u5ea6\u3001\u7f16\u7801\u7b5b\u9009\u3001\u8d77\u59cb\u5bc6\u7801\u5b50\u5904\u7406\u53ca\u6bcf\u6761\u8f6c\u5f55\u672c\u62a5\u544a\u591a\u5c11\u4e2a\u9605\u8bfb\u6846\u7b49\u884c\u4e3a\u3002\u4ecd\u6309\u65e7\u7248\u672c\u201c\u9ed8\u8ba4\u81f3\u5c11\u4e00\u767e\u6c28\u57fa\u9178\u201d\u201c\u9ed8\u8ba4\u62a5\u544a\u591a\u4e2a\u975e\u91cd\u53e0\u7ed3\u679c\u201d\u7684\u5370\u8c61\u89e3\u91ca\u65b0\u8f93\u51fa\uff0c\u53ef\u80fd\u4ece\u7b2c\u4e00\u6b65\u5c31\u4ea7\u751f\u504f\u5dee\u3002<\/p>\n

\u5f53\u524d\u7248\u672c\u7684\u5019\u9009\u6700\u77ed\u957f\u5ea6\u9ed8\u8ba4\u4e3a\u4e94\u5341\u4e2a\u6c28\u57fa\u9178\uff0c\u65e0\u540c\u6e90\u652f\u6301\u7684\u5019\u9009\u901a\u5e38\u9700\u8981\u901a\u8fc7\u7f16\u7801\u5206\u6570\u4e0e\u76ee\u6807\u8bf1\u9975\u68c0\u9a8c\uff0c\u9ed8\u8ba4 q \u503c\u95e8\u69db\u4e3a\u96f6\u70b9\u96f6\u4e94\u3002\u540c\u65f6\uff0c\u6bcf\u6761\u8f6c\u5f55\u672c\u9ed8\u8ba4\u62a5\u544a\u4e00\u4e2a\u6392\u540d\u6700\u4f18\u7684\u5019\u9009\uff0c\u5141\u8bb8\u591a\u4e2a\u5019\u9009\u9700\u8981\u660e\u786e\u5f00\u542f\u76f8\u5e94\u53c2\u6570\u3002\u4e03\u70b9\u96f6\u70b9\u96f6\u5b98\u65b9\u53d1\u5e03\u8bf4\u660e<\/a><\/p>\n

\u672c\u7bc7\u8fd0\u884c\u7684\u662f Perl \u5b9e\u73b0\u3002\u5b98\u65b9\u6587\u6863\u540c\u65f6\u63a8\u8350\u65b0\u7528\u6237\u8003\u8651 Python \u5b9e\u73b0 PyTransDecoder\uff0c\u4f46\u6211\u4eec\u6ca1\u6709\u5728\u8fd9\u6b21\u5b9e\u9a8c\u4e2d\u8fd0\u884c\u540e\u8005\uff0c\u4e0d\u63d0\u4f9b\u4e24\u8005\u7684\u5b9e\u6d4b\u901f\u7387\u6bd4\u8f83\u3002\u4e00\u4e2a\u9879\u76ee\u5185\u5e94\u56fa\u5b9a\u5b9e\u73b0\u3001\u7248\u672c\u548c\u7b5b\u9009\u89c4\u5219\uff0c\u4e0d\u5b9c\u5c06\u4e0d\u540c\u7248\u672c\u7684\u9ed8\u8ba4\u7ed3\u679c\u76f4\u63a5\u6df7\u6210\u540c\u4e00\u5f20\u77e9\u9635\u3002<\/p>\n

\u4e3a\u4ec0\u4e48\u8fd9\u6b21\u5c0f\u8f93\u5165\u4f7f\u7528\u9884\u8bbe\u6a21\u578b<\/h2>\n

TransDecoder \u4e0d\u53ea\u662f\u5bfb\u627e\u8d77\u59cb\u548c\u7ec8\u6b62\u5bc6\u7801\u5b50\uff0c\u8fd8\u9700\u8981\u5224\u65ad\u5019\u9009\u662f\u5426\u5177\u6709\u4e0e\u7f16\u7801\u5e8f\u5217\u4e00\u81f4\u7684\u7edf\u8ba1\u7279\u5f81\u3002\u5b8c\u6574\u8f6c\u5f55\u7ec4\u53ef\u4ee5\u63d0\u4f9b\u7528\u4e8e\u8bad\u7ec3\u7684\u5e8f\u5217\uff0c\u5c0f\u5230\u53ea\u6709\u51e0\u6761\u8f93\u5165\u65f6\uff0c\u4f9d\u9760\u8fd9\u4e9b\u6761\u76ee\u91cd\u65b0\u5b66\u4e60\u6a21\u578b\u5e76\u4e0d\u7a33\u59a5\u3002<\/p>\n

\u672c\u6b21\u53ea\u6709\u4e03\u6761\u8f93\u5165\uff0c\u56e0\u6b64\u91c7\u7528\u5b98\u65b9\u63d0\u4f9b\u7684\u54fa\u4e73\u52a8\u7269\u9884\u8bbe\u3002\u5b83\u63d0\u4f9b\u7f16\u7801\u6a21\u578b\u3001\u8d77\u59cb\u6a21\u578b\u548c\u76f8\u5e94\u9608\u503c\uff0c\u9002\u5408\u8fd9\u6b21\u6765\u81ea\u4eba\u7c7b\u53c2\u8003\u5e8f\u5217\u7684\u89c4\u5219\u6f14\u793a\u3002\u8f93\u51fa\u4e2d\u7684\u9884\u8bbe q \u503c\u8868\u4e5f\u8868\u660e\uff0c\u6211\u4eec\u4f7f\u7528\u7684\u662f\u53c2\u8003\u9884\u8bbe\u6240\u63d0\u4f9b\u7684\u5224\u5b9a\u4f53\u7cfb\uff0c\u5e76\u4e0d\u662f\u7528\u4e03\u6761\u5e8f\u5217\u72ec\u7acb\u5efa\u7acb\u4e86\u4e00\u5957\u53ef\u9760\u7684\u7ecf\u9a8c\u5206\u5e03\u3002TransDecoder \u5f53\u524d\u5b98\u65b9\u6587\u6863<\/a><\/p>\n

\u771f\u5b9e\u9879\u76ee\u5e94\u6839\u636e\u7269\u79cd\u3001\u5e8f\u5217\u6570\u91cf\u3001\u7ec4\u88c5\u5b8c\u6574\u6027\u548c\u9057\u4f20\u5bc6\u7801\u9009\u62e9\u8def\u5f84\u3002\u9884\u8bbe\u65b9\u4fbf\u4f7f\u7528\uff0c\u5374\u4e0d\u80fd\u4fdd\u8bc1\u4efb\u610f\u8fdc\u7f18\u7269\u79cd\u90fd\u9002\u7528\u3002\u5c24\u5176\u662f\u5b58\u5728\u4e0d\u540c\u7ec8\u6b62\u5bc6\u7801\u5b50\u89c4\u5219\u7684\u751f\u7269\uff0c\u9057\u4f20\u5bc6\u7801\u8bbe\u7f6e\u672c\u8eab\u5c31\u4f1a\u6539\u53d8\u5f00\u653e\u9605\u8bfb\u6846\u7684\u8fb9\u754c\uff0c\u4e0d\u80fd\u4ec5\u4f9d\u9760\u6362\u4e00\u4e2a\u9884\u8bbe\u540d\u79f0\u89e3\u51b3\u6240\u6709\u95ee\u9898\u3002<\/p>\n

\u8f93\u5165\u6765\u6e90\u548c\u4eba\u4e3a\u6539\u52a8\u90fd\u516c\u5f00<\/h2>\n

\u516c\u5171\u53c2\u8003\u4e3a TP53 \u7684 NM_000546.6<\/code> \u548c ACTB \u7684 NM_001101.5<\/code>\u3002\u811a\u672c\u4ece NCBI \u83b7\u53d6\u56fa\u5b9a\u7248\u672c\u8bb0\u5f55\uff0c\u6838\u5bf9\u5e8f\u5217\u6458\u8981\uff0c\u5e76\u6309\u8bb0\u5f55\u4e2d\u7684\u7f16\u7801\u533a\u5750\u6807\u63d0\u53d6\u7247\u6bb5\u3002TP53 \u7f16\u7801\u533a\u4e3a\u4e00\u57fa\u5236\u95ed\u533a\u95f4\u4e00\u767e\u56db\u5341\u4e09\u5230\u4e00\u5343\u4e09\u767e\u4e8c\u5341\u56db\uff0cACTB \u4e3a\u516b\u5341\u4e94\u5230\u4e00\u5343\u4e8c\u767e\u4e00\u5341\u4e8c\u3002<\/p>\n

\u6211\u4eec\u4fdd\u7559\u5b8c\u6574 TP53 \u8f6c\u5f55\u672c\uff0c\u540c\u65f6\u5206\u522b\u53bb\u6389\u5176\u7f16\u7801\u533a\u524d\u7aef\u4e5d\u5341\u78b1\u57fa\u3001\u540e\u7aef\u4e5d\u5341\u78b1\u57fa\uff0c\u4ee5\u53ca\u4e24\u7aef\u5404\u4e5d\u5341\u78b1\u57fa\u3002\u53e6\u628a TP53 \u7f16\u7801\u533a\u4e0e ACTB \u7f16\u7801\u533a\u901a\u8fc7\u7ec8\u6b62\u5bc6\u7801\u5b50\u95f4\u9694\u8fde\u63a5\uff0c\u6784\u9020\u53cc\u9605\u8bfb\u6846\u5e8f\u5217\uff0c\u518d\u6784\u9020\u4e00\u4e2a\u516d\u5341\u6c28\u57fa\u9178\u7247\u6bb5\u548c ACTB \u5168\u8f6c\u5f55\u672c\u7684\u53cd\u5411\u4e92\u8865\u5e8f\u5217\u3002<\/p>\n

\u6bcf\u4e00\u79cd\u6539\u52a8\u90fd\u6709\u660e\u786e\u7528\u9014\u3002\u622a\u77ed\u8f93\u5165\u68c0\u67e5\u8fb9\u754c\u4e0e\u5b8c\u6574\u6807\u7b7e\uff0c\u53cc\u9605\u8bfb\u6846\u68c0\u67e5\u62a5\u544a\u6570\u91cf\u548c\u6392\u5e8f\uff0c\u53cd\u5411\u8f93\u5165\u68c0\u67e5\u94fe\u9650\u5236\uff0c\u77ed\u7247\u6bb5\u68c0\u67e5\u5019\u9009\u63d0\u53d6\u4e0e\u6700\u7ec8\u4fdd\u7559\u662f\u5426\u4e3a\u540c\u4e00\u6b65\u3002\u5b83\u4eec\u4e0d\u662f\u751f\u7269\u6837\u672c\uff0c\u4e5f\u6ca1\u6709\u8fdb\u884c\u540c\u6e90\u6570\u636e\u5e93\u641c\u7d22\u3001\u6838\u7cd6\u4f53\u6d4b\u5e8f\u6216\u86cb\u767d\u8d28\u7ec4\u9a8c\u8bc1\u3002<\/p>\n

TP53 \u56fa\u5b9a\u7248\u672c\u8bb0\u5f55<\/a> \u548c ACTB \u56fa\u5b9a\u7248\u672c\u8bb0\u5f55<\/a> \u53ef\u7528\u4e8e\u6838\u5bf9\u6765\u6e90\u3002\u590d\u73b0\u9644\u4ef6\u540c\u65f6\u4fdd\u7559\u4e0b\u8f7d\u5730\u5740\u3001\u6458\u8981\u3001\u5750\u6807\u548c\u6240\u6709\u884d\u751f\u89c4\u5219\uff0c\u907f\u514d\u628a\u88c1\u526a\u540e\u7684\u6d4b\u8bd5\u5e8f\u5217\u8bef\u5f53\u6210\u539f\u59cb\u516c\u5171\u53c2\u8003\u3002<\/p>\n

\u5b89\u88c5\u540e\u4f7f\u7528\u5b9e\u9645\u53ef\u7528\u7684\u5165\u53e3<\/h2>\n

\u672c\u6b21\u5bb9\u5668\u5b9e\u9645\u62a5\u544a TransDecoder \u4e03\u70b9\u96f6\u70b9\u96f6\u3002\u65e7\u6559\u7a0b\u5e38\u7528\u7684\u5019\u9009\u63d0\u53d6\u547d\u4ee4\u5728\u8fd9\u4e2a\u5bb9\u5668\u4e2d\u4e0d\u76f4\u63a5\u4f4d\u4e8e\u53ef\u6267\u884c\u641c\u7d22\u8def\u5f84\uff0c\u4f46\u7edf\u4e00\u5165\u53e3\u80fd\u591f\u6b63\u5e38\u8c03\u7528\u6240\u9700\u6b65\u9aa4\u3002\u56e0\u6b64\uff0c\u53d1\u73b0\u65e7\u547d\u4ee4\u4e0d\u5b58\u5728\u65f6\uff0c\u5e94\u5148\u68c0\u67e5\u5f53\u524d\u5305\u88c5\u65b9\u5f0f\u548c\u5e2e\u52a9\uff0c\u800c\u4e0d\u662f\u7acb\u5373\u5224\u65ad\u6574\u4e2a\u8f6f\u4ef6\u5b89\u88c5\u5931\u8d25\u3002<\/p>\n

docker pull quay.io\/biocontainers\/transdecoder:7.0.0--pl5321hcbfc158_0\r\ndocker run --rm quay.io\/biocontainers\/transdecoder:7.0.0--pl5321hcbfc158_0 \\\r\n  TransDecoder --version\r\n\r\n# \u89e3\u538b\u590d\u73b0\u5305\u540e\uff0c\u5728\u5bf9\u5e94\u5de5\u5177\u76ee\u5f55\u6267\u884c\r\npython3 run.py .\/practice\r\n<\/code><\/pre>\n
\u56db\u7ec4\u5b9e\u9645\u8fd0\u884c\u90fd\u4f7f\u7528\u540c\u4e00\u4efd\u8f93\u5165\u548c\u54fa\u4e73\u52a8\u7269\u9884\u8bbe\u3002\u7b2c\u4e00\u7ec4\u641c\u7d22\u4e24\u6761\u94fe\uff0c\u7b2c\u4e8c\u7ec4\u4ec5\u641c\u7d22\u8f93\u5165\u5e8f\u5217\u6b63\u5411\uff0c\u7b2c\u4e09\u7ec4\u5728\u6b63\u5411\u641c\u7d22\u57fa\u7840\u4e0a\u5141\u8bb8\u591a\u4e2a\u975e\u91cd\u53e0\u5019\u9009\uff0c\u7b2c\u56db\u7ec4\u5728\u6b63\u5411\u641c\u7d22\u57fa\u7840\u4e0a\u53ea\u63a5\u53d7\u5b8c\u6574\u5019\u9009\u3002\u5206\u522b\u8f93\u51fa\u5230\u4e0d\u540c\u76ee\u5f55\uff0c\u907f\u514d\u91cd\u590d\u8fd0\u884c\u8986\u76d6\u4e2d\u95f4\u8bc1\u636e\u3002<\/p>\n
TransDecoder -t transcripts.fa --preset mammal -O both_strands\r\nTransDecoder -t transcripts.fa --preset mammal -S -O sense_only\r\nTransDecoder -t transcripts.fa --preset mammal -S \\\r\n  --retain_multiple_orfs -O multiple\r\nTransDecoder -t transcripts.fa --preset mammal -S \\\r\n  --complete_orfs_only -O complete_only\r\n<\/code><\/pre>\n
\u56db\u7ec4\u90fd\u6210\u529f\u9000\u51fa\u3002\u6211\u4eec\u540c\u65f6\u8bfb\u53d6\u4e2d\u95f4\u5019\u9009\u80bd\u6587\u4ef6\u3001\u6700\u7ec8\u80bd\u6587\u4ef6\u3001\u5750\u6807\u6ce8\u91ca\u548c\u9884\u8bbe q \u503c\u8868\u3002\u53ea\u4fdd\u5b58\u6700\u540e\u4e00\u4efd\u80bd\u5e8f\u5217\uff0c\u4f1a\u4e22\u5931\u201c\u66fe\u7ecf\u627e\u5230\u5019\u9009\uff0c\u4f46\u88ab\u54ea\u4e00\u6b65\u6392\u9664\u201d\u7684\u5173\u952e\u4fe1\u606f\u3002<\/p>\n
\u5019\u9009\u6570\u91cf\u4e0e\u6700\u7ec8\u6570\u91cf\u4e0d\u80fd\u6df7\u7528<\/h2>\n
\u4e24\u6761\u94fe\u90fd\u641c\u7d22\u65f6\uff0c\u4e2d\u95f4\u6587\u4ef6\u5171\u6709\u56db\u5341\u4e94\u4e2a\u5019\u9009\uff0c\u6700\u7ec8\u4fdd\u7559\u516d\u4e2a\u3002\u4ec5\u641c\u7d22\u6b63\u5411\u65f6\uff0c\u5019\u9009\u964d\u4e3a\u4e8c\u5341\u4e94\u4e2a\uff0c\u6700\u7ec8\u4e94\u4e2a\u3002\u5141\u8bb8\u591a\u4e2a\u5019\u9009\u540e\uff0c\u5019\u9009\u63d0\u53d6\u6570\u4ecd\u4e3a\u4e8c\u5341\u4e94\uff0c\u4f46\u6700\u7ec8\u589e\u52a0\u5230\u516d\u4e2a\u3002\u53ea\u63a5\u53d7\u5b8c\u6574\u5019\u9009\u65f6\uff0c\u4e2d\u95f4\u5019\u9009\u4e3a\u5341\u516b\uff0c\u6700\u7ec8\u4e09\u4e2a\u3002<\/p>\n
\n\n\n\n\n\n\n\n\n
\u8bbe\u7f6e<\/th>\n\u5019\u9009\u6570<\/th>\n\u6700\u7ec8\u6570<\/th>\n<\/tr>\n<\/thead>\n
\u4e24\u94fe\u641c\u7d22<\/td>\n45<\/td>\n6<\/td>\n<\/tr>\n
\u6b63\u5411\u641c\u7d22<\/td>\n25<\/td>\n5<\/td>\n<\/tr>\n
\u5141\u8bb8\u591a\u4e2a<\/td>\n25<\/td>\n6<\/td>\n<\/tr>\n
\u53ea\u8981\u5b8c\u6574<\/td>\n18<\/td>\n3<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
\u8fd9\u4e9b\u6570\u5b57\u5305\u542b\u4e0d\u540c\u9636\u6bb5\u7684\u4fe1\u606f\u3002\u94fe\u9650\u5236\u6539\u53d8\u641c\u7d22\u7a7a\u95f4\uff0c\u5b8c\u6574\u6027\u8bbe\u7f6e\u4e5f\u4f1a\u5f71\u54cd\u5019\u9009\u96c6\u5408\uff0c\u5141\u8bb8\u591a\u4e2a\u5019\u9009\u5219\u6539\u53d8\u540c\u4e00\u8f6c\u5f55\u672c\u4e0a\u6700\u7ec8\u80fd\u591f\u62a5\u544a\u591a\u5c11\u6761\u7ed3\u679c\u3002\u4e0d\u80fd\u628a\u6700\u7ec8\u6570\u91cf\u7684\u6240\u6709\u4e0b\u964d\u90fd\u89e3\u91ca\u6210\u7f16\u7801\u5206\u6570\u53d8\u5dee\uff0c\u4e5f\u4e0d\u80fd\u628a\u6570\u91cf\u589e\u52a0\u81ea\u52a8\u89e3\u91ca\u6210\u53d1\u73b0\u4e86\u66f4\u591a\u771f\u5b9e\u86cb\u767d\u3002<\/p>\n
\u5b9e\u9645\u6574\u7406\u7ed3\u679c\u65f6\uff0c\u5efa\u8bae\u4fdd\u7559\u5019\u9009\u6807\u8bc6\u3001\u6240\u5c5e\u8f6c\u5f55\u672c\u3001\u65b9\u5411\u3001\u5750\u6807\u3001\u5b8c\u6574\u6027\u3001\u7f16\u7801\u5206\u6570\u4e0e\u7b5b\u9009\u4fe1\u606f\u3002\u968f\u540e\u6309\u95ee\u9898\u7edf\u8ba1\uff0c\u4f8b\u5982\u591a\u5c11\u8f6c\u5f55\u672c\u81f3\u5c11\u6709\u4e00\u4e2a\u5019\u9009\u3001\u591a\u5c11\u5019\u9009\u5c5e\u4e8e\u90e8\u5206\u9605\u8bfb\u6846\u3002\u76f4\u63a5\u628a\u6700\u7ec8\u80bd\u6761\u6570\u5199\u6210\u57fa\u56e0\u6570\u91cf\uff0c\u4f1a\u628a\u5f02\u6784\u4f53\u3001\u591a\u4e2a\u5019\u9009\u548c\u7ec4\u88c5\u788e\u7247\u6df7\u5728\u4e00\u8d77\u3002<\/p>\n
\u516d\u5341\u6c28\u57fa\u9178\u5019\u9009\u88ab\u627e\u5230\uff0c\u4e0d\u7b49\u4e8e\u6700\u7ec8\u4fdd\u7559<\/h2>\n
\u4eba\u5de5\u77ed\u7247\u6bb5\u542b\u516d\u5341\u4e2a\u6c28\u57fa\u9178\u5bf9\u5e94\u7684\u7f16\u7801\u5e8f\u5217\u53ca\u4e00\u4e2a\u7ec8\u6b62\u5bc6\u7801\u5b50\uff0c\u8d85\u8fc7\u5f53\u524d\u9ed8\u8ba4\u5019\u9009\u957f\u5ea6\u95e8\u69db\u3002\u5b9e\u9645\u4e2d\u95f4\u6587\u4ef6\u786e\u5b9e\u627e\u5230\u4e86\u8fd9\u4e2a\u5b8c\u6574\u5019\u9009\uff0c\u8bf4\u660e\u5b83\u6ca1\u6709\u5728\u6700\u521d\u7684\u957f\u5ea6\u641c\u7d22\u4e2d\u6d88\u5931\u3002<\/p>\n
\u4f46\u56db\u7ec4\u6700\u7ec8\u7ed3\u679c\u90fd\u6ca1\u6709\u4fdd\u7559\u5b83\u3002\u5bf9\u5e94\u9884\u8bbe q \u503c\u4e3a\u4e00\uff0c\u672a\u6ee1\u8db3\u5f53\u524d\u9009\u62e9\u6761\u4ef6\u3002\u8fd9\u5c55\u793a\u4e86\u4e00\u4e2a\u975e\u5e38\u5177\u4f53\u7684\u533a\u522b\uff0c\u5019\u9009\u8db3\u591f\u957f\u3001\u5177\u6709\u8d77\u6b62\u8fb9\u754c\uff0c\u53ea\u80fd\u8ba9\u5b83\u8fdb\u5165\u8fdb\u4e00\u6b65\u8bc4\u4f30\uff0c\u5e76\u4e0d\u80fd\u81ea\u52a8\u901a\u8fc7\u7f16\u7801\u8bc1\u636e\u7b5b\u9009\u3002<\/p>\n
\u540c\u6837\uff0c\u672a\u4fdd\u7559\u4e5f\u4e0d\u80fd\u4f5c\u4e3a\u8be5\u7247\u6bb5\u7edd\u65e0\u7ffb\u8bd1\u53ef\u80fd\u7684\u8bc1\u660e\u3002\u8fd9\u662f\u5bf9\u4e00\u6761\u4eba\u4e3a\u88c1\u526a\u5e8f\u5217\u3001\u7279\u5b9a\u9884\u8bbe\u548c\u89c4\u5219\u7684\u8ba1\u7b97\u7ed3\u679c\u3002\u82e5\u7814\u7a76\u76ee\u6807\u672c\u6765\u5c31\u662f\u77ed\u5f00\u653e\u9605\u8bfb\u6846\uff0c\u9700\u8981\u7ed3\u5408\u72ec\u7acb\u8bc1\u636e\u8bc4\u4f30\u5019\u9009\uff0c\u800c\u4e0d\u662f\u5355\u7eaf\u964d\u4f4e\u957f\u5ea6\u95e8\u69db\u540e\u628a\u65b0\u589e\u6761\u76ee\u5168\u90e8\u5f53\u6210\u77ed\u80bd\u53d1\u73b0\u3002<\/p>\n
q \u503c\u8fd8\u5e94\u6309\u5176\u7edf\u8ba1\u7528\u9014\u89e3\u91ca\u3002\u5b83\u5e2e\u52a9\u63a7\u5236\u67d0\u7c7b\u7b5b\u9009\u7ed3\u679c\u4e2d\u7684\u9519\u8bef\u53d1\u73b0\uff0c\u4e0d\u80fd\u76f4\u63a5\u8bfb\u6210\u6bcf\u6761\u5019\u9009\u201c\u6709\u767e\u5206\u4e4b\u591a\u5c11\u6982\u7387\u662f\u771f\u86cb\u767d\u201d\u3002\u672c\u6b21\u4e00\u4e9b\u957f\u5019\u9009\u7684\u9884\u8bbe q \u503c\u4e3a\u96f6\uff0c\u4e5f\u4e0d\u610f\u5473\u7740\u5176\u6240\u6709\u7ed3\u6784\u548c\u751f\u7269\u5b66\u529f\u80fd\u90fd\u5df2\u7ecf\u88ab\u8bc1\u660e\u3002<\/p>\n
\u53cc\u9605\u8bfb\u6846\u8f93\u5165\u4e3a\u4ec0\u4e48\u4fdd\u7559\u8f83\u77ed\u7684\u90a3\u6761<\/h2>\n
\u4eba\u4e3a\u8fde\u63a5\u7684\u53cc\u9605\u8bfb\u6846\u5e8f\u5217\u4e2d\uff0c\u524d\u4e00\u6bb5\u5bf9\u5e94\u4e09\u767e\u4e5d\u5341\u4e09\u6c28\u57fa\u9178\u7684 TP53 \u5019\u9009\uff0c\u540e\u4e00\u6bb5\u5bf9\u5e94\u4e09\u767e\u4e03\u5341\u4e94\u6c28\u57fa\u9178\u7684 ACTB \u5019\u9009\u3002\u4e24\u8005\u90fd\u80fd\u591f\u901a\u8fc7\u672c\u6b21\u7b5b\u9009\uff0c\u4f46\u9ed8\u8ba4\u53ea\u62a5\u544a\u540e\u4e00\u6bb5\u8f83\u77ed\u7684\u5019\u9009\u3002<\/p>\n
\u5b9e\u9645\u8f93\u51fa\u4e2d\uff0c\u524d\u6bb5\u7f16\u7801\u5206\u6570\u7ea6\u4e3a\u4e00\u767e\u96f6\u4e09\u70b9\u4e8c\u4e5d\uff0c\u540e\u6bb5\u7ea6\u4e3a\u4e00\u767e\u4e00\u5341\u4e00\u70b9\u516d\u56db\u3002\u672c\u6b21\u6ca1\u6709\u63d0\u4f9b\u540c\u6e90\u8bc1\u636e\uff0c\u6392\u5e8f\u4f9d\u636e\u4e2d\u7684\u7f16\u7801\u5206\u6570\u5148\u4e8e\u957f\u5ea6\uff0c\u56e0\u6b64\u4e0d\u662f\u7b80\u5355\u5730\u4fdd\u7559\u66f4\u957f\u8005\u3002\u52a0\u5165\u5141\u8bb8\u591a\u4e2a\u975e\u91cd\u53e0\u5019\u9009\u7684\u53c2\u6570\u540e\uff0c\u4e24\u6bb5\u90fd\u8fdb\u5165\u6700\u7ec8\u7ed3\u679c\u3002<\/p>\n
\n\n\n\n\n\n\n
\u53cc\u6846\u5019\u9009<\/th>\n\u6c28\u57fa\u9178\u6570<\/th>\n\u7f16\u7801\u5206\u6570<\/th>\n<\/tr>\n<\/thead>\n
\u524d\u6bb5<\/td>\n393<\/td>\n103.29<\/td>\n<\/tr>\n
\u540e\u6bb5<\/td>\n375<\/td>\n111.64<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
\u8fd9\u5bf9\u89e3\u91ca\u771f\u5b9e\u7ec4\u88c5\u5f88\u6709\u7528\u3002\u82e5\u4e00\u4e2a\u8f6c\u5f55\u672c\u53ea\u8f93\u51fa\u4e00\u4e2a\u86cb\u767d\uff0c\u4e0d\u80fd\u636e\u6b64\u65ad\u5b9a\u5b83\u53ea\u542b\u4e00\u4e2a\u53ef\u8bc6\u522b\u9605\u8bfb\u6846\u3002\u82e5\u8f93\u51fa\u591a\u4e2a\u86cb\u767d\uff0c\u4e5f\u4e0d\u80fd\u7acb\u5373\u65ad\u5b9a\u5b58\u5728\u591a\u987a\u53cd\u5b50\u7ffb\u8bd1\u3002\u771f\u5b9e\u6570\u636e\u8fd8\u53ef\u80fd\u5305\u542b\u5d4c\u5408\u7ec4\u88c5\u3001\u672a\u5206\u5f00\u7684\u76f8\u90bb\u57fa\u56e0\u6216\u5176\u4ed6\u5f02\u5e38\uff0c\u9700\u8981\u56de\u5230\u8bfb\u6bb5\u548c\u7ed3\u6784\u8bc1\u636e\u3002<\/p>\n
\u7f16\u7801\u5206\u6570\u672c\u8eab\u4e5f\u4e0d\u80fd\u5145\u5f53\u529f\u80fd\u5f3a\u5f31\u6216\u8005\u8868\u8fbe\u9ad8\u4f4e\u7684\u6307\u6807\u3002\u5b83\u670d\u52a1\u4e8e\u5019\u9009\u7b5b\u9009\u548c\u6392\u5e8f\uff0c\u4e0d\u662f\u86cb\u767d\u6d3b\u6027\u6d4b\u91cf\u3002\u628a\u8fd9\u4e2a\u5206\u6570\u4e0e TPM \u6216\u5b9e\u9a8c\u6548\u5e94\u91cf\u653e\u5728\u540c\u4e00\u6761\u89e3\u91ca\u94fe\u4e0a\uff0c\u5bb9\u6613\u8d4b\u4e88\u5b83\u672c\u6765\u6ca1\u6709\u7684\u751f\u7269\u610f\u4e49\u3002<\/p>\n
\u622a\u53bb\u524d\u7aef\u4e4b\u540e\uff0c\u4e3a\u4ec0\u4e48\u4ecd\u7136\u6807\u4e3a\u5b8c\u6574<\/h2>\n
\u8fd9\u662f\u672c\u6b21\u6700\u503c\u5f97\u8b66\u60d5\u7684\u7ed3\u679c\u3002\u6211\u4eec\u4ece TP53 \u7f16\u7801\u533a\u5f00\u5934\u660e\u786e\u5220\u9664\u4e86\u4e5d\u5341\u78b1\u57fa\uff0c\u4f46\u6700\u7ec8\u8f93\u51fa\u4ecd\u628a\u4e00\u4e2a\u5019\u9009\u6807\u4e3a\u5b8c\u6574\u3002\u8be5\u5019\u9009\u4ece\u88c1\u526a\u540e\u5e8f\u5217\u7684\u7b2c\u4e8c\u5341\u516b\u78b1\u57fa\u5f00\u59cb\uff0c\u5230\u7ec8\u6b62\u4f4d\u7f6e\u7ed3\u675f\uff0c\u6700\u7ec8\u4e3a\u4e09\u767e\u4e94\u5341\u56db\u6c28\u57fa\u9178\uff0c\u6bd4\u5b8c\u6574\u53c2\u8003\u7684\u4e09\u767e\u4e5d\u5341\u4e09\u6c28\u57fa\u9178\u77ed\u3002<\/p>\n
\u539f\u56e0\u662f\u5b8c\u6574\u6807\u7b7e\u63cf\u8ff0\u5f53\u524d\u9884\u6d4b\u9605\u8bfb\u6846\u662f\u5426\u5177\u6709\u76f8\u5e94\u8d77\u6b62\u8fb9\u754c\uff0c\u5e76\u4e0d\u8bc1\u660e\u5b83\u8986\u76d6\u4e86\u53c2\u8003\u86cb\u767d\u7684\u5168\u90e8\u539f\u59cb\u4f4d\u7f6e\u3002\u5e8f\u5217\u5185\u90e8\u7684\u8d77\u59cb\u5bc6\u7801\u5b50\u53ef\u4ee5\u5f62\u6210\u4e00\u4e2a\u8fb9\u754c\u9f50\u5168\u7684\u8f83\u77ed\u5019\u9009\u3002\u6b64\u65f6\uff0c\u4ec5\u6839\u636e\u6807\u7b7e\u7b5b\u9009\u201c\u5b8c\u6574\u86cb\u767d\u201d\uff0c\u4ecd\u7136\u53ef\u80fd\u4fdd\u7559\u5df2\u7ecf\u4e22\u5931\u524d\u7aef\u7684\u6a21\u578b\u3002<\/p>\n
\u5f00\u542f\u53ea\u63a5\u53d7\u5b8c\u6574\u5019\u9009\u4e5f\u6ca1\u6709\u89e3\u51b3\u8fd9\u4e2a\u95ee\u9898\uff0c\u90a3\u6761\u8f83\u77ed\u5019\u9009\u4ecd\u7136\u88ab\u4fdd\u7559\u3002\u76f8\u53cd\uff0c\u53bb\u6389\u540e\u7aef\u7684\u8f93\u5165\u56e0\u4e3a\u7f3a\u5c11\u76f8\u5e94\u7ec8\u6b62\u8fb9\u754c\uff0c\u88ab\u62a5\u544a\u4e3a\u90e8\u5206\u9605\u8bfb\u6846\uff0c\u5e76\u5728\u5b8c\u6574\u6027\u9650\u5236\u7ec4\u4e2d\u88ab\u6392\u9664\u3002\u5b8c\u6574\u6027\u8fc7\u6ee4\u9075\u5faa\u5f53\u524d\u5019\u9009\u7684\u7ed3\u6784\u5b9a\u4e49\uff0c\u4e0d\u4f1a\u81ea\u52a8\u6062\u590d\u6211\u4eec\u5728\u8f93\u5165\u4e2d\u5220\u9664\u7684\u78b1\u57fa\u3002<\/p>\n
\u771f\u5b9e\u5206\u6790\u4e2d\u5e94\u8fdb\u4e00\u6b65\u6bd4\u8f83\u540c\u6e90\u86cb\u767d\u8986\u76d6\u3001\u5173\u952e\u7ed3\u6784\u57df\u548c\u8d77\u59cb\u4f4d\u7f6e\uff0c\u5e76\u67e5\u770b\u8f6c\u5f55\u672c\u662f\u5426\u672c\u6765\u5c31\u88ab\u7ec4\u88c5\u622a\u77ed\u3002\u82e5\u4e00\u4e2a\u5173\u952e\u86cb\u767d\u6bd4\u540c\u6e90\u5e8f\u5217\u77ed\u5f88\u591a\uff0c\u5373\u4f7f\u6807\u7b7e\u663e\u793a\u5b8c\u6574\uff0c\u4e5f\u503c\u5f97\u56de\u67e5\u3002\u5bf9\u4e8e\u5929\u7136\u5b58\u5728\u77ed\u5f02\u6784\u4f53\u7684\u57fa\u56e0\uff0c\u53c8\u4e0d\u80fd\u53cd\u8fc7\u6765\u628a\u6240\u6709\u8f83\u77ed\u5019\u9009\u90fd\u5224\u4e3a\u9519\u8bef\u3002<\/p>\n
\u94fe\u65b9\u5411\u9650\u5236\u5fc5\u987b\u5efa\u7acb\u5728\u5df2\u77e5\u65b9\u5411\u4e0a<\/h2>\n
\u53cd\u5411\u4e92\u8865\u7684 ACTB \u8f93\u5165\u5728\u4e24\u94fe\u641c\u7d22\u7ec4\u4e2d\u6062\u590d\u4e86\u6b63\u786e\u65b9\u5411\u4e0a\u7684\u4e09\u767e\u4e03\u5341\u4e94\u6c28\u57fa\u9178\u5019\u9009\u3002\u4ec5\u641c\u7d22\u8f93\u5165\u6b63\u5411\u540e\uff0c\u8fd9\u4e2a\u7ed3\u679c\u4e0d\u518d\u51fa\u73b0\u3002\u8f6f\u4ef6\u6ca1\u6709\u4e22\u5931\u6587\u4ef6\uff0c\u800c\u662f\u6211\u4eec\u4e3b\u52a8\u9650\u5236\u4e86\u5141\u8bb8\u641c\u7d22\u7684\u65b9\u5411\u3002<\/p>\n
\u56e0\u6b64\uff0c\u6b63\u5411\u9650\u5236\u9002\u5408\u5df2\u7ecf\u660e\u786e\u8f6c\u5f55\u65b9\u5411\u7684\u8f93\u5165\u3002\u5b83\u4e0d\u80fd\u7b80\u5355\u5bf9\u5e94\u201c\u539f\u59cb\u6d4b\u5e8f\u7b2c\u4e00\u7aef\u662f\u6b63\u94fe\u201d\uff0c\u4e5f\u4e0d\u80fd\u53ea\u56e0\u4e3a\u5019\u9009\u6570\u91cf\u51cf\u5c11\u5c31\u8ba4\u4e3a\u7b5b\u9009\u66f4\u4e25\u683c\u3001\u66f4\u53ef\u9760\u3002\u7ec4\u88c5\u540e\u7684\u5e8f\u5217\u662f\u5426\u5df2\u6309\u8f6c\u5f55\u65b9\u5411\u6392\u5217\uff0c\u9700\u8981\u7531\u5b9e\u9645\u6d41\u7a0b\u548c\u8bc1\u636e\u786e\u8ba4\u3002<\/p>\n
\u8fd9\u4e00\u5bf9\u7167\u4e5f\u8bf4\u660e\uff0c\u76f8\u540c\u7684\u6838\u9178\u5185\u5bb9\u6362\u4e00\u4e2a\u65b9\u5411\u8868\u793a\uff0c\u53ef\u80fd\u5728\u53d7\u9650\u641c\u7d22\u4e2d\u4ea7\u751f\u4e0d\u540c\u7ed3\u679c\u3002\u4fdd\u5b58\u5e8f\u5217\u7248\u672c\u548c\u65b9\u5411\u4fe1\u606f\uff0c\u4e0e\u4fdd\u5b58\u53c2\u6570\u4e00\u6837\u91cd\u8981\u3002\u8de8\u9879\u76ee\u6574\u5408\u5019\u9009\u65f6\uff0c\u81f3\u5c11\u5e94\u786e\u8ba4\u8f93\u5165\u65b9\u5411\u548c\u641c\u7d22\u8303\u56f4\u4e00\u81f4\uff0c\u518d\u6bd4\u8f83\u67d0\u4e9b\u86cb\u767d\u662f\u5426\u7f3a\u5931\u3002<\/p>\n
\u8f93\u51fa\u6587\u4ef6\u600e\u6837\u670d\u52a1\u540e\u7eed\u5206\u6790<\/h2>\n
\u6700\u7ec8\u80bd\u6587\u4ef6\u9002\u5408\u7528\u4e8e\u86cb\u767d\u5c42\u9762\u7684\u540c\u6e90\u6216\u7ed3\u6784\u57df\u5206\u6790\uff0c\u7f16\u7801\u6838\u9178\u6587\u4ef6\u4fdd\u7559\u5bf9\u5e94\u6838\u82f7\u9178\u5e8f\u5217\uff0c\u5750\u6807\u6587\u4ef6\u7528\u4e8e\u628a\u5019\u9009\u653e\u56de\u8f93\u5165\u8f6c\u5f55\u672c\u3002\u82e5\u8f93\u5165\u6765\u81ea\u57fa\u56e0\u7ec4\u6ce8\u91ca\u63d0\u53d6\u7684\u8f6c\u5f55\u672c\uff0c\u8f6c\u5f55\u672c\u5750\u6807\u4e0e\u57fa\u56e0\u7ec4\u5750\u6807\u8fd8\u9700\u8981\u6b63\u786e\u8f6c\u6362\uff0c\u4e0d\u80fd\u76f4\u63a5\u6df7\u7528\u3002<\/p>\n
\u5019\u9009\u6587\u4ef6\u3001\u6700\u7ec8\u6587\u4ef6\u548c\u7b5b\u9009\u8bb0\u5f55\u6700\u597d\u4e00\u8d77\u5f52\u6863\u3002\u8fd9\u6837\u53d1\u73b0\u67d0\u6761\u7ed3\u679c\u7f3a\u5931\u65f6\uff0c\u53ef\u4ee5\u533a\u5206\u6ca1\u6709\u641c\u7d22\u5230\u3001\u5b58\u5728\u5019\u9009\u4f46\u672a\u901a\u8fc7\u3001\u88ab\u540c\u4e00\u8f6c\u5f55\u672c\u4e0a\u7684\u5176\u4ed6\u5019\u9009\u53d6\u4ee3\uff0c\u8fd8\u662f\u88ab\u65b9\u5411\u6216\u5b8c\u6574\u6027\u89c4\u5219\u6392\u9664\u3002\u8fd9\u79cd\u53ef\u8ffd\u6eaf\u6027\u6bd4\u5355\u7eaf\u4fdd\u7559\u4e00\u4e2a\u6700\u7ec8\u86cb\u767d\u6570\u91cf\u66f4\u6709\u4ef7\u503c\u3002<\/p>\n
\u672c\u6b21\u6ca1\u6709\u6267\u884c\u5916\u90e8\u540c\u6e90\u548c\u7ed3\u6784\u57df\u641c\u7d22\uff0c\u56e0\u6b64\u4e0d\u58f0\u79f0\u4efb\u4f55\u5019\u9009\u83b7\u5f97\u4e86\u8fd9\u4e9b\u8bc1\u636e\u3002\u6b63\u5f0f\u7814\u7a76\u53ef\u4ee5\u6839\u636e\u95ee\u9898\u8865\u5145\uff0c\u4f46\u5e94\u628a\u8ba1\u7b97\u9884\u6d4b\u3001\u6570\u636e\u5e93\u652f\u6301\u548c\u5b9e\u9a8c\u9a8c\u8bc1\u5206\u522b\u8868\u8ff0\u3002\u5c24\u5176\u662f\u77ed\u5019\u9009\u548c\u5f02\u5e38\u8fde\u63a5\u6765\u6e90\u7684\u5019\u9009\uff0c\u66f4\u9700\u8981\u660e\u786e\u54ea\u4e9b\u8bc1\u636e\u5df2\u7ecf\u5b58\u5728\uff0c\u54ea\u4e9b\u4ecd\u7136\u7f3a\u5931\u3002<\/p>\n
\u5b9e\u8dd1\u540e\u7684\u5224\u65ad<\/h2>\n
TransDecoder \u7684\u4f18\u52bf\u662f\u628a\u9605\u8bfb\u6846\u641c\u7d22\u3001\u7f16\u7801\u7279\u5f81\u3001\u8d77\u59cb\u4f4d\u7f6e\u548c\u53ef\u9009\u540c\u6e90\u652f\u6301\u7ec4\u7ec7\u6210\u53ef\u8ffd\u67e5\u7684\u9884\u6d4b\u6d41\u7a0b\uff0c\u9002\u5408\u8f6c\u5f55\u672c\u7ec4\u88c5\u540e\u7684\u5019\u9009\u7f16\u7801\u533a\u6574\u7406\u3002\u9650\u5236\u5728\u4e8e\u6a21\u578b\u4f9d\u8d56\u8f93\u5165\u3001\u7269\u79cd\u80cc\u666f\u548c\u8bbe\u7f6e\uff0c\u8f93\u51fa\u8fb9\u754c\u5b8c\u6574\u5e76\u4e0d\u4fdd\u8bc1\u53c2\u8003\u8986\u76d6\u5b8c\u6574\uff0c\u4fdd\u7559\u4e00\u4e2a\u6700\u4f18\u5019\u9009\u4e5f\u4e0d\u4ee3\u8868\u5176\u4ed6\u5019\u9009\u4e0d\u5b58\u5728\u3002<\/p>\n
\u8fd9\u6b21\u56db\u7ec4\u5b9e\u8dd1\u7ed9\u51fa\u4e09\u4e2a\u80fd\u591f\u76f4\u63a5\u8fc1\u79fb\u7684\u68c0\u67e5\u52a8\u4f5c\u3002\u5148\u533a\u5206\u5019\u9009\u6587\u4ef6\u4e0e\u6700\u7ec8\u6587\u4ef6\uff0c\u518d\u68c0\u67e5\u540c\u4e00\u8f6c\u5f55\u672c\u7684\u6392\u5e8f\u548c\u4fdd\u7559\u89c4\u5219\uff0c\u6700\u540e\u628a\u5b8c\u6574\u6807\u7b7e\u653e\u56de\u539f\u59cb\u5e8f\u5217\u4e0e\u53c2\u8003\u8986\u76d6\u4e2d\u5224\u65ad\u3002\u8fd9\u6837\u8bfb\u8005\u770b\u5230\u4e00\u4e2a\u5b8c\u6574\u9605\u8bfb\u6846\u65f6\uff0c\u80fd\u591f\u77e5\u9053\u5b83\u7a76\u7adf\u8bc1\u660e\u4e86\u4ec0\u4e48\uff0c\u4ee5\u53ca\u8fd8\u9700\u8981\u6838\u5bf9\u4ec0\u4e48\u3002<\/p>\n
\u4e0b\u8f7d\u672c\u7ec4\u590d\u73b0\u811a\u672c\u548c\u5b9e\u9645\u8f93\u51fa<\/a>\uff0c\u5176\u4e2d\u5305\u542b\u516c\u5171\u8bb0\u5f55\u6458\u8981\u3001\u6240\u6709\u4eba\u4e3a\u6539\u52a8\u3001\u56db\u7ec4\u5019\u9009\u4e0e\u6700\u7ec8\u5e8f\u5217\uff0c\u4ee5\u53ca\u5b9e\u9645\u9884\u8bbe q \u503c\u8868\u3002<\/p>\n
\u5f53\u5019\u9009\u7b5b\u9009\u89c4\u5219\u5df2\u7ecf\u660e\u786e\uff0c\u9700\u8981\u628a\u591a\u6279\u8f6c\u5f55\u672c\u7684\u9884\u6d4b\u3001\u540c\u6e90\u641c\u7d22\u548c\u6ce8\u91ca\u7ed3\u679c\u653e\u5728\u4e00\u81f4\u73af\u5883\u4e2d\u5904\u7406\u65f6\uff0c\u53ef\u4e86\u89e3\u4e91\u751f\u4fe1\u751f\u7269\u4fe1\u606f\u5b66\u5206\u6790\u670d\u52a1\u5668\u670d\u52a1<\/a>\u3002<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"
\u57fa\u4e8e\u56fa\u5b9a\u7248\u672c\u516c\u5171\u8f6c\u5f55\u672c\u548c\u4eba\u5de5\u884d\u751f\u5e8f\u5217\uff0c\u5b9e\u8dd1 TransDecoder 7\uff0c\u89e3\u91ca\u5019\u9009\u7b5b\u9009\u3001\u5355\u4e2a\u6700\u4f18 ORF\u3001\u94fe\u65b9\u5411\u4e0e\u5b8c\u6574\u6807\u7b7e\u7684\u8fb9\u754c\u3002<\/p>\n","protected":false},"author":1,"featured_media":73092,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[49],"tags":[1356,1355,1299,1357],"class_list":["post-73093","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-software","tag-orf","tag-transdecoder","tag-1299","tag-1357"],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2026\/11\/transdecoder7-orf-complete-ranking-strand-preset-practice-guide.png?fit=1200%2C840&ssl=1","_links":{"self":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/73093","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/comments?post=73093"}],"version-history":[{"count":1,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/73093\/revisions"}],"predecessor-version":[{"id":73097,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/73093\/revisions\/73097"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/media\/73092"}],"wp:attachment":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/media?parent=73093"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/categories?post=73093"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/tags?post=73093"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}