{"id":73196,"date":"2026-11-15T14:50:21","date_gmt":"2026-11-15T06:50:21","guid":{"rendered":"https:\/\/www.biocloudservice.com\/wordpress\/?p=73196"},"modified":"2026-11-15T14:50:21","modified_gmt":"2026-11-15T06:50:21","slug":"wgcna-signed-unsigned-negative-correlation-module-practice","status":"publish","type":"post","link":"https:\/\/www.biocloudservice.com\/wordpress\/wgcna-signed-unsigned-negative-correlation-module-practice\/","title":{"rendered":"WGCNA \u5b9e\u8dd1\u590d\u76d8\uff0c\u5f3a\u8d1f\u76f8\u5173\u7684\u57fa\u56e0\u4e3a\u4ec0\u4e48\u4f1a\u8fdb\u5165\u540c\u4e00\u4e2a\u6a21\u5757"},"content":{"rendered":"
\n

\u770b\u5230\u4e24\u4e2a\u57fa\u56e0\u7684\u76f8\u5173\u7cfb\u6570\u63a5\u8fd1\u8d1f\u4e00\uff0c\u5374\u88ab WGCNA \u5206\u5230\u540c\u4e00\u6a21\u5757\uff0c\u5f88\u591a\u4eba\u4f1a\u6000\u7591\u7a0b\u5e8f\u5206\u9519\u4e86\u3002\u5b9e\u9645\u4e0a\uff0c\u662f\u5426\u4fdd\u7559\u76f8\u5173\u65b9\u5411\uff0c\u662f\u5efa\u7f51\u65f6\u5fc5\u987b\u660e\u786e\u7684\u9009\u62e9\u3002\u672c\u6b21\u8ba9\u4e24\u7ec4\u4eba\u5de5\u57fa\u56e0\u5206\u522b\u8ddf\u968f\u540c\u4e00\u4e2a\u53d8\u5316\u8d8b\u52bf\u53ca\u5176\u76f8\u53cd\u65b9\u5411\uff0c\u5b9e\u9645\u8fd0\u884c\u4e24\u79cd\u7f51\u7edc\uff0c\u5f97\u5230\u622a\u7136\u4e0d\u540c\u7684\u5f52\u7ec4\u7ed3\u679c\u3002<\/p>\n

\u8fd9\u7bc7\u6587\u7ae0\u56f4\u7ed5\u8fd9\u4e00\u7ec4\u5bf9\u7167\u89e3\u91ca\u76f8\u5173\u7cfb\u6570\u3001\u8fde\u63a5\u6743\u91cd\u3001\u6a21\u5757\u6210\u5458\u548c\u6a21\u5757\u7279\u5f81\u5411\u91cf\u4e4b\u95f4\u7684\u5173\u7cfb\u3002\u540c\u65f6\u8fd0\u884c\u8f93\u5165\u8d28\u91cf\u68c0\u67e5\u3001\u4e00\u4e2a\u5f02\u5e38\u70b9\u76f8\u5173\u6027\u7ec3\u4e60\u548c\u4e00\u6b21\u6837\u672c\u5b50\u96c6\u5bf9\u7167\u3002\u6240\u6709\u6570\u636e\u5747\u4e3a\u6a21\u62df\u8868\u8fbe\u503c\uff0c\u4e0d\u662f\u67d0\u79cd\u7ec4\u7ec7\u7684\u771f\u5b9e\u53d1\u73b0\uff0c\u4e5f\u6ca1\u6709\u628a\u6784\u9020\u51fa\u6765\u7684\u9ad8\u76f8\u5173\u5f53\u4f5c\u751f\u7269\u5b66\u9a8c\u8bc1\u3002<\/p>\n

\"\u540c\u4e00\u6a21\u5757\uff0c\u672a\u5fc5\u540c\u5411\u53d8\u5316\u300240
40 \u4e2a\u6a21\u62df\u6837\u672c \u00b7 \u4e24\u79cd\u7f51\u7edc\u5b9a\u4e49\u7684\u5b9e\u9645\u5bf9\u7167<\/figcaption><\/figure>\n

\u8f93\u5165\u77e9\u9635\u7684\u65b9\u5411\u5148\u68c0\u67e5\u6e05\u695a<\/h2>\n

\u672c\u6b21\u5b89\u88c5 WGCNA 1.74\uff0c\u8f93\u5165\u6309\u6837\u672c\u4e3a\u884c\u3001\u7279\u5f81\u4e3a\u5217\u7ec4\u7ec7\u3002\u6709\u6548\u6570\u636e\u6709\u56db\u5341\u4e2a\u6837\u672c\u3001\u4e00\u767e\u56db\u5341\u4e2a\u7279\u5f81\u3002\u7532\u7ec4\u56db\u5341\u4e2a\u7279\u5f81\u8ddf\u968f\u7b2c\u4e00\u4e2a\u6f5c\u5728\u8d8b\u52bf\uff0c\u4e59\u7ec4\u56db\u5341\u4e2a\u7279\u5f81\u8ddf\u968f\u5b83\u7684\u76f8\u53cd\u65b9\u5411\uff0c\u4e19\u7ec4\u56db\u5341\u4e2a\u7279\u5f81\u8ddf\u968f\u53e6\u4e00\u4e2a\u8d8b\u52bf\uff0c\u5269\u4f59\u4e8c\u5341\u4e2a\u662f\u72ec\u7acb\u566a\u58f0\u7279\u5f81\u3002<\/p>\n

\u6a21\u62df\u503c\u662f\u8fde\u7eed\u7684\u8868\u8fbe\u578b\u6570\u636e\uff0c\u53ef\u4ee5\u51fa\u73b0\u8d1f\u503c\u3002\u5b83\u4eec\u4e0d\u662f\u539f\u59cb\u6d4b\u5e8f\u8ba1\u6570\uff0c\u4e5f\u6ca1\u6709\u7ecf\u8fc7\u771f\u5b9e\u6570\u636e\u7684\u6807\u51c6\u5316\u6216\u65b9\u5dee\u7a33\u5b9a\u53d8\u6362\u3002\u56e0\u6b64\uff0c\u672c\u5b9e\u9a8c\u53ea\u68c0\u9a8c\u5efa\u7f51\u548c\u7ed3\u679c\u89e3\u91ca\uff0c\u4e0d\u9a8c\u8bc1\u4ece\u539f\u59cb\u8bfb\u6bb5\u5230\u8868\u8fbe\u77e9\u9635\u7684\u51c6\u5907\u8fc7\u7a0b\u3002\u5c06\u81ea\u5df1\u7684\u539f\u59cb\u8ba1\u6570\u76f4\u63a5\u4ee3\u5165\u8fd9\u91cc\u7684\u793a\u4f8b\uff0c\u5e76\u4e0d\u81ea\u52a8\u83b7\u5f97\u76f8\u540c\u7684\u8f93\u5165\u6761\u4ef6\u3002<\/p>\n

\u4e3a\u4e86\u68c0\u9a8c\u5165\u53e3\u68c0\u67e5\uff0c\u6211\u4eec\u989d\u5916\u52a0\u5165\u4e00\u5217\u5e38\u6570\u3001\u4e00\u5217\u5168\u7f3a\u5931\uff0c\u4ee5\u53ca\u4e00\u4e2a\u5168\u90e8\u7f3a\u5931\u7684\u6837\u672c\u3002\u5b9e\u9645\u8c03\u7528\u8d28\u91cf\u68c0\u67e5\u540e\uff0c\u8fd9\u4e09\u9879\u88ab\u6392\u9664\uff0c\u8f93\u5165\u4ece\u56db\u5341\u4e00\u884c\u3001\u4e00\u767e\u56db\u5341\u4e8c\u5217\u53d8\u6210\u56db\u5341\u884c\u3001\u4e00\u767e\u56db\u5341\u5217\u3002\u68c0\u67e5\u7ed3\u679c\u4e0e\u9884\u5148\u5b89\u6392\u7684\u5f02\u5e38\u4e00\u81f4\uff0c\u8bf4\u660e\u6d41\u7a0b\u786e\u5b9e\u5904\u7406\u4e86\u8fd9\u4e9b\u65e0\u6cd5\u63d0\u4f9b\u6709\u6548\u76f8\u5173\u4fe1\u606f\u7684\u9879\u76ee\u3002<\/p>\n

\u8fd9\u7c7b\u68c0\u67e5\u4e0d\u7b49\u4e8e\u6837\u672c\u8d28\u91cf\u5df2\u7ecf\u5168\u9762\u5408\u683c\u3002\u4e00\u4e2a\u6837\u672c\u5373\u4f7f\u6ca1\u6709\u7f3a\u5931\u503c\uff0c\u4e5f\u53ef\u80fd\u5b58\u5728\u6279\u6b21\u5f71\u54cd\u3001\u9519\u6807\u6216\u5f02\u5e38\u5206\u5e03\u3002\u8d28\u91cf\u68c0\u67e5\u7ed9\u51fa\u7684\u901a\u8fc7\uff0c\u53ea\u5bf9\u5e94\u5176\u68c0\u67e5\u9879\u76ee\u3002\u6b63\u5f0f\u5206\u6790\u4ecd\u5e94\u67e5\u770b\u6837\u672c\u5173\u7cfb\u548c\u5b9e\u9a8c\u8bb0\u5f55\uff0c\u800c\u4e0d\u662f\u7528\u4e00\u4e2a\u5168\u90e8\u901a\u8fc7\u7684\u5e03\u5c14\u503c\u66ff\u4ee3\u6570\u636e\u7406\u89e3\u3002<\/p>\n

qc <- goodSamplesGenes(dirty, verbose = 0)\r\nclean <- dirty[qc$goodSamples, qc$goodGenes]\r\nstopifnot(identical(dim(clean), c(40L, 140L)))\r\n<\/code><\/pre>\n
\u76f8\u5173\u7cfb\u6570\u548c\u8fde\u63a5\u6743\u91cd\u4e0d\u662f\u540c\u4e00\u4e2a\u6570<\/h2>\n
\u5728\u6709\u6548\u77e9\u9635\u4e2d\uff0c\u7532\u7ec4\u7b2c\u4e00\u4e2a\u7279\u5f81\u4e0e\u4e59\u7ec4\u7b2c\u4e00\u4e2a\u7279\u5f81\u7684\u76f8\u5173\u7cfb\u6570\u7ea6\u4e3a\u8d1f\u96f6\u70b9\u4e5d\u516d\u516b\uff0c\u7b26\u5408\u6211\u4eec\u5b89\u6392\u7684\u76f8\u53cd\u53d8\u5316\u8d8b\u52bf\u3002\u968f\u540e\u5206\u522b\u8ba1\u7b97\u65e0\u7b26\u53f7\u7f51\u7edc\u548c\u6709\u7b26\u53f7\u7f51\u7edc\u7684\u8fde\u63a5\u6743\u91cd\uff0c\u5e42\u90fd\u56fa\u5b9a\u4e3a\u516d\u3002\u8fd9\u4e2a\u5e42\u503c\u53ea\u662f\u672c\u6b21\u63a7\u5236\u53d8\u91cf\u7684\u8bbe\u7f6e\uff0c\u6ca1\u6709\u901a\u8fc7\u8f6f\u9608\u503c\u9009\u62e9\u8fc7\u7a0b\u4f18\u5316\uff0c\u4e5f\u4e0d\u4f5c\u4e3a\u901a\u7528\u63a8\u8350\u503c\u3002<\/p>\n
\u65e0\u7b26\u53f7\u7f51\u7edc\u4f7f\u7528\u76f8\u5173\u5f3a\u5ea6\u7684\u7edd\u5bf9\u503c\uff0c\u56e0\u6b64\u5f3a\u8d1f\u76f8\u5173\u4ecd\u7136\u5bf9\u5e94\u5f3a\u8fde\u63a5\u3002\u6709\u7b26\u53f7\u7f51\u7edc\u4fdd\u7559\u65b9\u5411\u4fe1\u606f\uff0c\u540c\u6837\u7684\u5f3a\u8d1f\u76f8\u5173\u88ab\u8f6c\u6362\u4e3a\u63a5\u8fd1\u96f6\u7684\u8fde\u63a5\u3002\u4e24\u79cd\u5b9a\u4e49\u670d\u52a1\u4e8e\u4e0d\u540c\u95ee\u9898\uff0c\u4e0d\u80fd\u4ec5\u6839\u636e\u54ea\u4e00\u79cd\u5f97\u5230\u7684\u6a21\u5757\u66f4\u591a\u5c31\u8bc4\u4ef7\u4f18\u52a3\u3002\u76f8\u5173\u7f51\u7edc\u548c\u52a0\u6743\u8fde\u63a5\u7684\u57fa\u672c\u601d\u60f3\u89c1 WGCNA \u65b9\u6cd5\u8bba\u6587<\/a>\u3002<\/p>\n
\n\n\n\n\n\n\n\n
\u6838\u5bf9\u5bf9\u8c61<\/th>\n\u65e0\u7b26\u53f7\u7f51\u7edc<\/th>\n\u6709\u7b26\u53f7\u7f51\u7edc<\/th>\n<\/tr>\n<\/thead>\n
\u7532\u4e00\u4e0e\u4e59\u4e00\u7684\u76f8\u5173\u7cfb\u6570<\/td>\n\u22120.9676<\/td>\n\u22120.9676<\/td>\n<\/tr>\n
\u540c\u4e00\u5bf9\u7279\u5f81\u7684\u8fde\u63a5\u6743\u91cd<\/td>\n0.8208<\/td>\n\u7ea6 1.8e-11<\/td>\n<\/tr>\n
\u7532\u4e00\u4e0e\u7532\u4e8c\u7684\u8fde\u63a5\u6743\u91cd<\/td>\n0.9035<\/td>\n0.9507<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
\u7b2c\u4e00\u884c\u76f8\u540c\uff0c\u540e\u4e24\u884c\u4e0d\u540c\uff0c\u662f\u56e0\u4e3a\u53d8\u6362\u89c4\u5219\u6539\u53d8\u4e86\uff0c\u5e76\u975e\u91cd\u65b0\u89c2\u5bdf\u5230\u4e86\u53e6\u4e00\u4efd\u8868\u8fbe\u6570\u636e\u3002\u5c24\u5176\u4e0d\u80fd\u628a\u8fde\u63a5\u6743\u91cd\u96f6\u70b9\u516b\u4e8c\u89e3\u91ca\u4e3a\u4e24\u8005\u6709\u767e\u5206\u4e4b\u516b\u5341\u4e8c\u7684\u76f8\u4e92\u4f5c\u7528\u6982\u7387\u3002\u5b83\u662f\u5f53\u524d\u5b9a\u4e49\u548c\u53c2\u6570\u4e0b\u7684\u7f51\u7edc\u6743\u91cd\uff0c\u542b\u4e49\u9700\u8981\u8fde\u540c\u8ba1\u7b97\u89c4\u5219\u4e00\u8d77\u62a5\u544a\u3002<\/p>\n
\u76f8\u540c\u5e42\u503c\u4e5f\u4e0d\u4fdd\u8bc1\u4e24\u79cd\u7f51\u7edc\u4e2d\u7684\u6743\u91cd\u53ef\u4ee5\u9010\u9879\u5f53\u6210\u540c\u4e00\u5c3a\u5ea6\u89e3\u91ca\u3002\u8868\u4e2d\u7684\u6b63\u76f8\u5173\u8fde\u63a5\u5728\u4e24\u79cd\u5b9a\u4e49\u4e0b\u4e5f\u6709\u5dee\u522b\u3002\u6bd4\u8f83\u7f51\u7edc\u65f6\uff0c\u5e94\u9996\u5148\u660e\u786e\u5e0c\u671b\u4fdd\u7559\u54ea\u7c7b\u5173\u7cfb\uff0c\u518d\u5728\u8be5\u5b9a\u4e49\u5185\u8bc4\u4f30\u53c2\u6570\uff0c\u800c\u4e0d\u662f\u628a\u67d0\u4e2a\u6570\u5b57\u8f83\u5927\u76f4\u63a5\u5f53\u4f5c\u8bc1\u636e\u66f4\u5145\u5206\u3002<\/p>\n
\u4e24\u79cd\u5b9a\u4e49\u5b9e\u9645\u5f97\u5230\u4e86\u600e\u6837\u7684\u6a21\u5757<\/h2>\n
\u6211\u4eec\u5728\u540c\u4e00\u77e9\u9635\u4e0a\u8fd0\u884c\u6a21\u5757\u8bc6\u522b\uff0c\u6700\u5c0f\u6a21\u5757\u5927\u5c0f\u8bbe\u4e3a\u4e8c\u5341\uff0c\u5408\u5e76\u9608\u503c\u8bbe\u4e3a\u96f6\u70b9\u4e8c\u4e94\uff0c\u76f8\u5173\u65b9\u6cd5\u5747\u4f7f\u7528 Pearson\u3002\u4e24\u6b21\u5206\u522b\u6307\u5b9a\u7f51\u7edc\u7c7b\u578b\u53ca\u5bf9\u5e94\u7684\u62d3\u6251\u91cd\u53e0\u7c7b\u578b\u3002\u5176\u4f59\u4e3b\u8981\u6761\u4ef6\u4fdd\u6301\u4e00\u81f4\uff0c\u4ee5\u4fbf\u628a\u7ed3\u679c\u5dee\u5f02\u4e0e\u76f8\u5173\u65b9\u5411\u7684\u5904\u7406\u8054\u7cfb\u8d77\u6765\u3002<\/p>\n
\u65e0\u7b26\u53f7\u7f51\u7edc\u5c06\u7532\u7ec4\u548c\u4e59\u7ec4\u5408\u5e76\u4e3a\u4e00\u4e2a\u516b\u5341\u7279\u5f81\u7684\u6a21\u5757\uff0c\u4e19\u7ec4\u5f62\u6210\u56db\u5341\u7279\u5f81\u7684\u6a21\u5757\uff0c\u4e8c\u5341\u4e2a\u566a\u58f0\u7279\u5f81\u672a\u88ab\u5206\u914d\u3002\u6709\u7b26\u53f7\u7f51\u7edc\u5c06\u7532\u3001\u4e59\u3001\u4e19\u5206\u6210\u4e09\u4e2a\u5404\u56db\u5341\u7279\u5f81\u7684\u6a21\u5757\uff0c\u540c\u6837\u7559\u4e0b\u4e8c\u5341\u4e2a\u672a\u5206\u914d\u7279\u5f81\u3002\u4eba\u5de5\u6784\u9020\u7684\u76f8\u53cd\u53d8\u5316\u6a21\u5f0f\uff0c\u5728\u8fd9\u4e24\u5957\u5b9a\u4e49\u4e0b\u5f97\u5230\u7684\u5f52\u7ec4\u6b63\u597d\u4e0d\u540c\u3002<\/p>\n
\n\n\n\n\n\n\n\n\n
\u7ed3\u679c\u7c7b\u522b<\/th>\n\u65e0\u7b26\u53f7\u7f51\u7edc<\/th>\n\u6709\u7b26\u53f7\u7f51\u7edc<\/th>\n<\/tr>\n<\/thead>\n
\u7532\u7ec4\u4e0e\u4e59\u7ec4<\/td>\n\u5408\u5e76\u4e3a 80 \u4e2a\u7279\u5f81<\/td>\n\u5206\u6210 40 \u4e0e 40<\/td>\n<\/tr>\n
\u4e19\u7ec4<\/td>\n40 \u4e2a\u7279\u5f81<\/td>\n40 \u4e2a\u7279\u5f81<\/td>\n<\/tr>\n
\u672a\u5206\u914d\u7279\u5f81<\/td>\n20<\/td>\n20<\/td>\n<\/tr>\n
\u5df2\u8bc6\u522b\u6a21\u5757\u6570<\/td>\n2<\/td>\n3<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
\u672a\u5206\u914d\u7c7b\u522b\u5728\u672c\u6b21\u6570\u5b57\u6807\u7b7e\u4e2d\u8bb0\u4e3a\u96f6\uff0c\u5e38\u88ab\u663e\u793a\u6210\u7070\u8272\u3002\u5b83\u4e0d\u5e94\u548c\u8bc6\u522b\u51fa\u7684\u6a21\u5757\u4e00\u8d77\uff0c\u76f4\u63a5\u8ba1\u5165\u5177\u6709\u540c\u7b49\u542b\u4e49\u7684\u6a21\u5757\u6570\u91cf\u3002\u82e5\u62a5\u544a\u91cc\u5199\u6709\u4e09\u4e2a\u989c\u8272\u7c7b\u522b\u548c\u4e09\u4e2a\u6a21\u5757\uff0c\u8bfb\u8005\u53ef\u80fd\u8bef\u4ee5\u4e3a\u7070\u8272\u4e5f\u662f\u4e00\u4e2a\u540c\u6837\u7d27\u5bc6\u7684\u5171\u8868\u8fbe\u7fa4\u4f53\uff0c\u5b9e\u9645\u542b\u4e49\u5e76\u975e\u5982\u6b64\u3002<\/p>\n
\u6a21\u5757\u7f16\u53f7\u548c\u989c\u8272\u4e5f\u4e0d\u662f\u8de8\u8fd0\u884c\u7a33\u5b9a\u7684\u8eab\u4efd\u6807\u8bc6\u3002\u672c\u6b21\u7532\u7ec4\u5728\u4e24\u6b21\u8fd0\u884c\u4e2d\u7684\u7f16\u53f7\u4e0d\u540c\uff0c\u5e76\u4e0d\u8bf4\u660e\u57fa\u56e0\u540d\u79f0\u6539\u53d8\u3002\u6bd4\u8f83\u4e24\u4efd\u7ed3\u679c\uff0c\u5e94\u6839\u636e\u6210\u5458\u5173\u7cfb\u6216\u7279\u5b9a\u6620\u5c04\u6838\u5bf9\uff0c\u800c\u4e0d\u662f\u628a\u7b2c\u4e00\u4efd\u7ed3\u679c\u4e2d\u7684\u84dd\u8272\uff0c\u4e0e\u7b2c\u4e8c\u4efd\u7ed3\u679c\u4e2d\u7684\u84dd\u8272\u76f4\u63a5\u89c6\u4f5c\u540c\u4e00\u751f\u7269\u5b66\u5bf9\u8c61\u3002<\/p>\n
\u6a21\u5757\u4e0e\u6027\u72b6\u6b63\u76f8\u5173\uff0c\u4e0d\u4ee3\u8868\u6240\u6709\u6210\u5458\u540c\u5411\u53d8\u5316<\/h2>\n
\u5728\u65e0\u7b26\u53f7\u7f51\u7edc\u7684\u516b\u5341\u7279\u5f81\u6a21\u5757\u4e2d\uff0c\u6a21\u5757\u7279\u5f81\u5411\u91cf\u4e0e\u7b2c\u4e00\u4e2a\u4eba\u5de5\u8d8b\u52bf\u51e0\u4e4e\u5b8c\u5168\u6b63\u76f8\u5173\u3002\u4f46\u662f\u7532\u7ec4\u7b2c\u4e00\u4e2a\u7279\u5f81\u4e0e\u8be5\u5411\u91cf\u7684\u76f8\u5173\u7ea6\u4e3a\u96f6\u70b9\u4e5d\u4e5d\u96f6\uff0c\u4e59\u7ec4\u7b2c\u4e00\u4e2a\u7279\u5f81\u4e0e\u8be5\u5411\u91cf\u7684\u76f8\u5173\u7ea6\u4e3a\u8d1f\u96f6\u70b9\u4e5d\u516b\u4e03\u3002\u4e24\u8005\u90fd\u5728\u540c\u4e00\u4e2a\u6a21\u5757\uff0c\u5374\u5904\u5728\u76f8\u53cd\u65b9\u5411\u3002<\/p>\n
\u8fd9\u7ed9\u51fa\u4e00\u4e2a\u5f88\u5177\u4f53\u7684\u53cd\u4f8b\u3002\u82e5\u4ec5\u770b\u5230\u6a21\u5757\u4e0e\u67d0\u4e2a\u6027\u72b6\u6b63\u76f8\u5173\uff0c\u5c31\u628a\u6a21\u5757\u5185\u6240\u6709\u57fa\u56e0\u90fd\u5199\u6210\u968f\u6027\u72b6\u5347\u9ad8\u800c\u5347\u9ad8\uff0c\u4f1a\u9519\u8bef\u89e3\u91ca\u5176\u4e2d\u4e00\u534a\u4eba\u5de5\u7279\u5f81\u3002\u6a21\u5757\u7684\u6458\u8981\u5173\u7cfb\u4e0d\u80fd\u66ff\u4ee3\u9010\u57fa\u56e0\u65b9\u5411\u68c0\u67e5\u3002\u7279\u522b\u662f\u4f7f\u7528\u65e0\u7b26\u53f7\u7f51\u7edc\u65f6\uff0c\u6210\u5458\u53ef\u80fd\u56f4\u7ed5\u540c\u4e00\u53d8\u5316\u8f74\u5448\u76f8\u53cd\u8d8b\u52bf\u3002<\/p>\n
\u6a21\u5757\u7279\u5f81\u5411\u91cf\u672c\u8eab\u8fd8\u6709\u65b9\u5411\u7ea6\u5b9a\u7684\u95ee\u9898\uff0c\u4e0d\u80fd\u8131\u79bb\u5f53\u524d\u8f93\u51fa\u5c06\u7b26\u53f7\u5f53\u4f5c\u56fa\u5b9a\u751f\u7269\u5b66\u6807\u7b7e\u3002\u66f4\u7a33\u59a5\u7684\u505a\u6cd5\u662f\u67e5\u770b\u4ee3\u8868\u7279\u5f81\u3001\u6210\u5458\u4e0e\u6458\u8981\u5411\u91cf\u7684\u76f8\u5173\uff0c\u4ee5\u53ca\u8868\u8fbe\u6a21\u5f0f\u56fe\uff0c\u5e76\u628a\u6bd4\u8f83\u65b9\u5411\u5199\u6e05\u695a\u3002\u6570\u503c\u6807\u7b7e\u53ea\u662f\u6574\u7406\u5de5\u5177\uff0c\u5b9e\u9645\u89e3\u91ca\u5e94\u56de\u5230\u6570\u636e\u4e2d\u7684\u53d8\u5316\u5173\u7cfb\u3002<\/p>\n
\u672c\u4f8b\u4e2d\u6a21\u5757\u4e0e\u4eba\u5de5\u8d8b\u52bf\u7684\u76f8\u5173\u63a5\u8fd1\u4e00\uff0c\u662f\u56e0\u4e3a\u8868\u8fbe\u503c\u672c\u6765\u5c31\u6309\u8be5\u8d8b\u52bf\u751f\u6210\u3002\u5b83\u8bc1\u660e\u4ee3\u7801\u627e\u56de\u4e86\u8bbe\u8ba1\u4e2d\u7684\u7ed3\u6784\uff0c\u4e0d\u662f\u72ec\u7acb\u53d1\u73b0\u4e86\u4e00\u4e2a\u5f3a\u751f\u7269\u5b66\u5173\u8054\u3002\u771f\u5b9e\u9879\u76ee\u91cc\u7684\u6027\u72b6\u82e5\u4e0e\u6279\u6b21\u3001\u7ec4\u7ec7\u6bd4\u4f8b\u6216\u5176\u4ed6\u56e0\u7d20\u76f8\u5173\uff0c\u8fd8\u9700\u8981\u8fdb\u4e00\u6b65\u5206\u6790\u8fd9\u4e9b\u53ef\u80fd\u5171\u540c\u9a71\u52a8\u8868\u8fbe\u7684\u6765\u6e90\u3002<\/p>\n
\u4e00\u4e2a\u5f02\u5e38\u70b9\u80fd\u628a\u76f8\u5173\u65b9\u5411\u7ffb\u8fc7\u6765<\/h2>\n
\u6211\u4eec\u53e6\u505a\u4e86\u4e00\u4e2a\u72ec\u7acb\u7684\u53cc\u53d8\u91cf\u7ec3\u4e60\uff0c\u672a\u5c06\u5b83\u6df7\u5165\u4e0a\u8ff0\u6a21\u5757\u6570\u636e\u3002\u5148\u8ba9\u56db\u5341\u5bf9\u6570\u503c\u6cbf\u540c\u4e00\u65b9\u5411\u53d8\u5316\uff0c\u518d\u628a\u6700\u540e\u4e00\u5bf9\u6539\u6210\u4e00\u4e2a\u53d8\u91cf\u7279\u522b\u5927\u3001\u53e6\u4e00\u4e2a\u7279\u522b\u5c0f\u3002\u5b9e\u9645\u8ba1\u7b97\u7684 Pearson \u76f8\u5173\u7ea6\u4e3a\u8d1f\u96f6\u70b9\u516b\u56db\u4e09\uff0c\u7a33\u5065\u76f8\u5173\u7ea6\u4e3a\u6b63\u96f6\u70b9\u4e5d\u4e5d\u516d\u3002<\/p>\n
\u8fd9\u8bf4\u660e\u4e00\u4e2a\u9ad8\u5f71\u54cd\u89c2\u6d4b\u53ef\u4ee5\u4e3b\u5bfc\u666e\u901a\u76f8\u5173\uff0c\u751a\u81f3\u4f7f\u65b9\u5411\u4e0e\u5176\u4f59\u5927\u591a\u6570\u89c2\u6d4b\u76f8\u53cd\u3002\u4f46\u4e0d\u80fd\u636e\u6b64\u628a\u6240\u6709\u4e0e\u603b\u4f53\u6a21\u5f0f\u4e0d\u540c\u7684\u70b9\u90fd\u5220\u9664\u3002\u5b83\u53ef\u80fd\u6765\u81ea\u6280\u672f\u5f02\u5e38\uff0c\u4e5f\u53ef\u80fd\u6765\u81ea\u771f\u5b9e\u7684\u4e9a\u7fa4\u6216\u53cc\u5cf0\u5206\u5e03\uff0c\u662f\u5426\u5e94\u5f53\u964d\u4f4e\u5f71\u54cd\u9700\u8981\u7ed3\u5408\u7814\u7a76\u95ee\u9898\u5224\u65ad\u3002<\/p>\n
\u672c\u6b21\u7a33\u5065\u76f8\u5173\u53ea\u7528\u4e8e\u8fd9\u4e00\u5bf9\u53d8\u91cf\uff0c\u6ca1\u6709\u91cd\u8dd1\u5b8c\u6574\u7684\u7a33\u5065\u7f51\u7edc\u3002\u56e0\u6b64\uff0c\u6587\u7ae0\u4e0d\u4f1a\u58f0\u79f0\u7a33\u5065\u65b9\u6cd5\u5df2\u7ecf\u4fee\u590d\u4e86\u6240\u6709\u6a21\u5757\uff0c\u4e5f\u6ca1\u6709\u636e\u6b64\u6bd4\u8f83\u4e24\u5957\u5b8c\u6574\u7f51\u7edc\u7684\u4f18\u52a3\u3002\u5b9e\u73b0\u548c\u65b9\u6cd5\u80cc\u666f\u53ef\u53c2\u8003 \u7a33\u5065\u76f8\u5173\u51fd\u6570\u8bba\u6587<\/a>\u3002<\/p>\n
stats::cor(x, y)\r\nbicor(x, y, maxPOutliers = 0.1)\r\n<\/code><\/pre>\n
\u4f5c\u8005\u7684 \u5e38\u89c1\u95ee\u9898\u8bf4\u660e<\/a> \u5bf9\u7a33\u5065\u76f8\u5173\u5728\u53cc\u5cf0\u6570\u636e\u4e2d\u7684\u884c\u4e3a\u6709\u4e13\u95e8\u63d0\u9192\uff0c\u4e5f\u8ba8\u8bba\u4e86\u9650\u5236\u5f02\u5e38\u6bd4\u4f8b\u7684\u8bbe\u7f6e\u3002\u8be5\u8bf4\u660e\u8fd8\u5f3a\u8c03\u5c0f\u6837\u672c\u76f8\u5173\u7684\u4e0d\u7a33\u5b9a\u6027\u3002\u9009\u62e9\u76f8\u5173\u65b9\u6cd5\u524d\uff0c\u5148\u770b\u6570\u636e\u5206\u5e03\u53ca\u6837\u672c\u7ed3\u6784\uff0c\u6bd4\u4ec5\u628a\u65b9\u6cd5\u540d\u79f0\u4ece\u666e\u901a\u6539\u6210\u7a33\u5065\u66f4\u91cd\u8981\u3002<\/p>\n
\u5b50\u96c6\u8fd0\u884c\u8bf4\u660e\u4e86\u4ec0\u4e48\uff0c\u53c8\u6ca1\u6709\u8bf4\u660e\u4ec0\u4e48<\/h2>\n
\u4e3a\u4e86\u67e5\u770b\u6837\u672c\u53d8\u5316\uff0c\u6211\u4eec\u9884\u5148\u6307\u5b9a\u53d6\u524d\u9762\u4e09\u5341\u4e2a\u6837\u672c\uff0c\u91cd\u65b0\u8fd0\u884c\u6709\u7b26\u53f7\u7f51\u7edc\u3002\u7ed3\u679c\u4ecd\u6709\u4e09\u4e2a\u4e3b\u8981\u6a21\u5757\uff0c\u4f46\u5176\u4e2d\u4e00\u4e2a\u6a21\u5757\u53d8\u6210\u56db\u5341\u4e00\u4e2a\u7279\u5f81\uff0c\u672a\u5206\u914d\u6570\u91cf\u4ece\u4e8c\u5341\u964d\u5230\u5341\u4e5d\u3002\u5177\u4f53\u53d8\u5316\u662f\u566a\u58f0\u7279\u5f81 N16<\/code> \u4ece\u672a\u5206\u914d\u7c7b\u522b\u8fdb\u5165\u4e86\u4e00\u4e2a\u6a21\u5757\u3002<\/p>\n
\u8fd9\u4e2a\u4f8b\u5b50\u8bf4\u660e\uff0c\u6574\u4f53\u6a21\u5757\u7ed3\u6784\u770b\u8d77\u6765\u76f8\u8fd1\u65f6\uff0c\u8fb9\u754c\u6210\u5458\u4ecd\u53ef\u80fd\u6539\u53d8\u3002\u5bf9\u4e8e\u51c6\u5907\u6311\u9009\u540e\u7eed\u5b9e\u9a8c\u5019\u9009\u7684\u7814\u7a76\uff0c\u4e0d\u80fd\u53ea\u6bd4\u8f83\u6a21\u5757\u603b\u6570\uff0c\u8fd8\u5e94\u67e5\u770b\u5019\u9009\u662f\u5426\u5728\u4e0d\u540c\u5408\u7406\u8bbe\u7f6e\u4e0b\u4fdd\u6301\u540c\u6837\u5173\u7cfb\u3002\u82e5\u5019\u9009\u6070\u597d\u5904\u4e8e\u5f52\u7ec4\u8fb9\u7f18\uff0c\u62a5\u544a\u4e2d\u5e94\u4fdd\u7559\u8fd9\u79cd\u4e0d\u786e\u5b9a\u6027\u3002<\/p>\n
\u4f46\u6211\u4eec\u53ea\u8fd0\u884c\u4e86\u4e00\u4e2a\u56fa\u5b9a\u5b50\u96c6\uff0c\u6ca1\u6709\u8fdb\u884c\u53cd\u590d\u62bd\u6837\u3001\u7f6e\u6362\u68c0\u9a8c\u3001\u72ec\u7acb\u961f\u5217\u590d\u73b0\u6216\u6a21\u5757\u4fdd\u5b58\u6027\u68c0\u9a8c\u3002\u7ed3\u679c\u8bb0\u5f55\u4e2d\u7684\u914d\u5bf9\u5f52\u7c7b\u4e00\u81f4\u7387\u8fd8\u5305\u542b\u672a\u5206\u914d\u6807\u7b7e\uff0c\u4e0d\u80fd\u5f53\u4f5c\u6807\u51c6\u6a21\u5757\u4fdd\u5b58\u6027\u7edf\u8ba1\u91cf\u3002\u56e0\u6b64\u672c\u6587\u4e0d\u628a\u4e00\u6b21\u5b50\u96c6\u7ed3\u679c\u5199\u6210\u7f51\u7edc\u5df2\u7ecf\u7a33\u5b9a\u9a8c\u8bc1\uff0c\u800c\u53ea\u628a\u5b83\u4f5c\u4e3a\u68c0\u67e5\u5165\u53e3\u3002<\/p>\n
\u9700\u8981\u6b63\u5f0f\u8bc4\u4ef7\u7a33\u5b9a\u6027\u65f6\uff0c\u5e94\u9884\u5148\u786e\u5b9a\u8bc4\u4ef7\u76ee\u6807\u3002\u662f\u5173\u6ce8\u6a21\u5757\u6574\u4f53\u662f\u5426\u4fdd\u7559\uff0c\u8fd8\u662f\u5173\u6ce8\u67d0\u4e2a\u57fa\u56e0\u7684\u6210\u5458\u5173\u7cfb\uff0c\u6216\u8005\u5173\u6ce8\u6a21\u5757\u4e0e\u6027\u72b6\u7684\u5173\u8054\u662f\u5426\u91cd\u73b0\u3002\u4e0d\u540c\u95ee\u9898\u9700\u8981\u4e0d\u540c\u8bc1\u636e\uff0c\u4e0d\u80fd\u7528\u4e00\u4e2a\u5f88\u9ad8\u7684\u4e00\u81f4\u7387\u66ff\u4ee3\u6240\u6709\u5c42\u9762\u7684\u9a8c\u8bc1\u3002<\/p>\n
\u53c2\u6570\u63a7\u5236\u4e0e\u53ef\u590d\u73b0\u8fd0\u884c<\/h2>\n
\u5b8c\u6574\u811a\u672c\u89c1 \u672c\u7ec4\u5b9e\u8dd1\u8d44\u6599<\/a>\u3002\u9a71\u52a8\u7a0b\u5e8f\u5728\u56fa\u5b9a\u73af\u5883\u4e2d\u5b89\u88c5\u8f6f\u4ef6\uff0c\u751f\u6210\u8f93\u5165\uff0c\u8fd0\u884c\u8d28\u91cf\u68c0\u67e5\u3001\u4e24\u79cd\u7f51\u7edc\u548c\u5b50\u96c6\u5bf9\u7167\uff0c\u5e76\u4fdd\u5b58\u8868\u8fbe\u77e9\u9635\u3001\u4eba\u5de5\u8d8b\u52bf\u3001\u6a21\u5757\u6210\u5458\u53ca\u7279\u5f81\u5411\u91cf\u3002\u8fdb\u5165 WGCNA \u5bf9\u5e94\u76ee\u5f55\u540e\u6267\u884c\u4ee5\u4e0b\u547d\u4ee4\u5373\u53ef\u91cd\u5efa\u672c\u5b9e\u9a8c\u3002<\/p>\n
python3 run.py run160\r\n<\/code><\/pre>\n
\u4e0b\u9762\u662f\u6709\u7b26\u53f7\u7f51\u7edc\u5bf9\u7167\u4e2d\u7684\u4e3b\u8981\u8bbe\u7f6e\u3002\u5b83\u7528\u4e8e\u8bf4\u660e\u672c\u6b21\u5b9e\u9645\u8fd0\u884c\u6761\u4ef6\uff0c\u4e0d\u662f\u53ef\u4ee5\u4e0d\u770b\u6570\u636e\u5c31\u4f7f\u7528\u7684\u6700\u4f73\u53c2\u6570\u7ec4\u5408\u3002\u5168\u90e8\u53c2\u6570\u53ca\u968f\u673a\u79cd\u5b50\u4fdd\u5b58\u5728\u9a71\u52a8\u811a\u672c\u4e2d\uff0c\u4fbf\u4e8e\u68c0\u67e5\u6bcf\u6b21\u4fee\u6539\u7a76\u7adf\u6539\u53d8\u4e86\u4ec0\u4e48\u3002<\/p>\n
net <- blockwiseModules(\r\n  clean, power = 6,\r\n  networkType = "signed", TOMType = "signed",\r\n  corType = "pearson", minModuleSize = 20,\r\n  mergeCutHeight = 0.25, numericLabels = TRUE,\r\n  reassignThreshold = 0, pamRespectsDendro = FALSE,\r\n  maxBlockSize = 200, randomSeed = 160, verbose = 0\r\n)\r\n<\/code><\/pre>\n
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\u56e0\u6b64\uff0c\u6269\u5927\u5206\u6790\u524d\u5e94\u5148\u660e\u786e\u7279\u5f81\u8fc7\u6ee4\u4e0e\u5206\u5757\u7b56\u7565\uff0c\u907f\u514d\u628a\u6240\u6709\u4e2d\u95f4\u77e9\u9635\u90fd\u65e0\u6761\u4ef6\u4fdd\u7559\u3002\u53e6\u4e00\u65b9\u9762\uff0c\u4e5f\u4e0d\u5b9c\u4e3a\u4e86\u5f97\u5230\u66f4\u660e\u663e\u7684\u6a21\u5757\uff0c\u5148\u6309\u540c\u4e00\u4e2a\u6027\u72b6\u7b5b\u51fa\u663e\u8457\u5dee\u5f02\u57fa\u56e0\u518d\u5efa\u7f51\u3002\u90a3\u4f1a\u6539\u53d8\u8f93\u5165\u7684\u76f8\u5173\u7ed3\u6784\uff0c\u4f7f\u540e\u7eed\u4e0e\u8be5\u6027\u72b6\u7684\u5173\u7cfb\u66f4\u96be\u4f5c\u4e3a\u72ec\u7acb\u8bc1\u636e\u89e3\u91ca\u3002<\/p>\n
\u4f18\u70b9\u3001\u5c40\u9650\u548c\u5b9e\u9645\u9009\u7528<\/h2>\n
WGCNA \u7684\u5b9e\u7528\u4f18\u52bf\u662f\u80fd\u591f\u628a\u5927\u91cf\u7279\u5f81\u7684\u5171\u540c\u53d8\u5316\u7ec4\u7ec7\u6210\u6a21\u5757\uff0c\u518d\u4ee5\u6a21\u5757\u5c42\u9762\u7684\u6458\u8981\u8fde\u63a5\u5230\u7814\u7a76\u95ee\u9898\u3002\u672c\u6b21\u4e24\u79cd\u7f51\u7edc\u7684\u5bf9\u7167\u8bf4\u660e\uff0c\u5b83\u5141\u8bb8\u4f7f\u7528\u8005\u660e\u786e\u9009\u62e9\u662f\u5426\u5c06\u76f8\u53cd\u65b9\u5411\u7684\u53d8\u5316\u89c6\u4f5c\u76f8\u8fd1\u5173\u7cfb\u3002\u53ef\u68c0\u67e5\u7684\u6210\u5458\u8868\u548c\u7279\u5f81\u5411\u91cf\uff0c\u4e5f\u65b9\u4fbf\u628a\u6982\u62ec\u6027\u7ed3\u8bba\u8ffd\u6eaf\u5230\u5177\u4f53\u7279\u5f81\u3002<\/p>\n
\u5b83\u7684\u5c40\u9650\u5728\u4e8e\u76f8\u5173\u7ed3\u6784\u5bb9\u6613\u53d7\u6837\u672c\u7ec4\u6210\u3001\u5f02\u5e38\u89c2\u6d4b\u548c\u53c2\u6570\u5f71\u54cd\u3002\u6a21\u5757\u5e76\u4e0d\u81ea\u52a8\u7b49\u4e8e\u901a\u8def\uff0c\u8fde\u63a5\u4e5f\u4e0d\u81ea\u52a8\u7b49\u4e8e\u8c03\u63a7\u5173\u7cfb\u3002\u4e00\u4e2a\u6a21\u5757\u4e2d\u6311\u51fa\u7684\u67a2\u7ebd\u7279\u5f81\uff0c\u4ecd\u9700\u8981\u6839\u636e\u8868\u8fbe\u8d28\u91cf\u3001\u7a33\u5b9a\u6027\u548c\u72ec\u7acb\u8bc1\u636e\u51b3\u5b9a\u662f\u5426\u503c\u5f97\u540e\u7eed\u9a8c\u8bc1\uff0c\u4e0d\u80fd\u4ec5\u51ed\u8fde\u63a5\u5ea6\u8f83\u9ad8\u5c31\u79f0\u5176\u4e3a\u9a71\u52a8\u56e0\u7d20\u3002<\/p>\n
\u8fd0\u884c\u6210\u529f\u4e4b\u540e\uff0c\u6700\u5e94\u8865\u4e0a\u7684\u4e0d\u662f\u66f4\u591a\u989c\u8272\uff0c\u800c\u662f\u5bf9\u7f51\u7edc\u5b9a\u4e49\u548c\u6210\u5458\u65b9\u5411\u7684\u89e3\u91ca\u3002\u5f3a\u8d1f\u76f8\u5173\u4e3a\u4ec0\u4e48\u88ab\u5206\u5230\u4e00\u8d77\uff0c\u6a21\u5757\u5173\u8054\u662f\u5426\u88ab\u5c11\u91cf\u89c2\u6d4b\u9a71\u52a8\uff0c\u5019\u9009\u662f\u5426\u5904\u4e8e\u5f52\u7ec4\u8fb9\u754c\u3002\u628a\u8fd9\u4e9b\u95ee\u9898\u8bf4\u6e05\u695a\uff0c\u6a21\u5757\u7ed3\u679c\u624d\u771f\u6b63\u80fd\u591f\u652f\u6301\u4e0b\u4e00\u6b65\u7814\u7a76\u5224\u65ad\u3002<\/p>\n
\u5f53\u660e\u786e\u7684\u5efa\u7f51\u65b9\u6848\u9700\u8981\u6269\u5c55\u5230\u66f4\u591a\u961f\u5217\u6216\u91cd\u590d\u5206\u6790\u65f6\uff0c\u53ef\u7ed3\u5408\u7279\u5f81\u89c4\u6a21\u4e86\u89e3 \u4e91\u751f\u4fe1\u751f\u7269\u4fe1\u606f\u5b66\u5206\u6790\u670d\u52a1\u5668\u670d\u52a1<\/a>\u3002<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"
\u5b9e\u8dd1 WGCNA \u8d28\u91cf\u68c0\u67e5\u3001\u4e24\u79cd\u7f51\u7edc\u548c\u6837\u672c\u5b50\u96c6\uff0c\u6bd4\u8f83\u8d1f\u76f8\u5173\u5982\u4f55\u8f6c\u6362\u4e3a\u8fde\u63a5\uff0c\u8bf4\u660e\u6a21\u5757\u7279\u5f81\u5411\u91cf\u3001\u7a33\u5065\u76f8\u5173\u53ca\u6210\u5458\u7a33\u5b9a\u6027\u7684\u89e3\u91ca\u8fb9\u754c\u3002<\/p>\n","protected":false},"author":1,"featured_media":73195,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[49],"tags":[80,243,590,1391],"class_list":["post-73196","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-software","tag-rna-seq","tag-wgcna","tag-590","tag-1391"],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.biocloudservice.com\/wordpress\/wp-content\/uploads\/2026\/11\/wgcna-signed-unsigned-negative-correlation-module-practice-guide.png?fit=1200%2C840&ssl=1","_links":{"self":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/73196","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/comments?post=73196"}],"version-history":[{"count":1,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/73196\/revisions"}],"predecessor-version":[{"id":73200,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/posts\/73196\/revisions\/73200"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/media\/73195"}],"wp:attachment":[{"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/media?parent=73196"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/categories?post=73196"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.biocloudservice.com\/wordpress\/wp-json\/wp\/v2\/tags?post=73196"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}