{"id":73236,"date":"2026-11-15T15:18:39","date_gmt":"2026-11-15T07:18:39","guid":{"rendered":"https:\/\/www.biocloudservice.com\/wordpress\/?p=73236"},"modified":"2026-11-15T15:18:39","modified_gmt":"2026-11-15T07:18:39","slug":"meme-suite-motif-sites-background-bh-coordinate-reading","status":"publish","type":"post","link":"https:\/\/www.biocloudservice.com\/wordpress\/meme-suite-motif-sites-background-bh-coordinate-reading\/","title":{"rendered":"MEME Suite \u7ed3\u679c\u89e3\u8bfb\uff0c\u57fa\u5e8f\u547d\u4e2d\u3001\u5bcc\u96c6\u663e\u8457\u548c\u8f6c\u5f55\u56e0\u5b50\u7ed3\u5408\u662f\u4e09\u4ef6\u4e8b"},"content":{"rendered":"
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\u672c\u6587\u4ecb\u7ecd MEME Suite \u5e38\u89c1\u7ed3\u679c\u7684\u9605\u8bfb\u65b9\u6cd5\uff0c\u5e76\u63d0\u4f9b\u5df2\u6267\u884c\u7684\u81ea\u7f16\u8bfb\u8868\u4e0e\u7edf\u8ba1\u7ec3\u4e60\u3002\u672c\u6587\u6ca1\u6709\u5b89\u88c5\u6216\u8fd0\u884c MEME Suite\uff0c\u4e5f\u6ca1\u6709\u4ea7\u751f\u771f\u5b9e\u7684\u57fa\u5e8f\u626b\u63cf\u3001\u53d1\u73b0\u6216\u5bcc\u96c6\u7ed3\u679c\u3002\u5957\u4ef6\u7684\u5b98\u65b9\u8bb8\u53ef\u8bf4\u660e<\/a>\u5bf9\u5546\u4e1a\u7528\u9014\u53e6\u6709\u8054\u7cfb\u8981\u6c42\uff0c\u672c\u6b21\u91c7\u7528\u516c\u5f00\u6587\u6863\u89e3\u8bfb\u4e0e\u539f\u521b\u6559\u5b66\u6570\u636e\uff0c\u6240\u6709\u7ec3\u4e60\u6570\u5b57\u90fd\u660e\u786e\u4fdd\u7559\u5176\u6765\u6e90\uff0c\u4e0d\u80fd\u5f53\u4f5c\u8f6f\u4ef6\u5b9e\u6d4b\u6027\u80fd\u3002<\/p>\n

\"\u547d\u4e2d\u3001\u5bcc\u96c6\u548c\u7ed3\u5408\uff0c\u5206\u522b\u9700\u8981\u8bc1\u636e\u3002\u6587\u6863\u89e3\u8bfb\u4e0e\u539f\u521b\u7ec3\u4e60
\u6587\u6863\u89e3\u8bfb\u4e0e\u539f\u521b\u7ec3\u4e60 \u00b7 \u672a\u8fd0\u884c\u5957\u4ef6\u8f6f\u4ef6<\/figcaption><\/figure>\n

\u4e00\u3001\u5148\u6839\u636e\u95ee\u9898\u9009\u5de5\u5177\uff0c\u4e0d\u8981\u6839\u636e\u719f\u6089\u7684\u540d\u5b57\u9009<\/h2>\n

\u5982\u679c\u4e0d\u77e5\u9053\u5e8f\u5217\u4e2d\u53ef\u80fd\u6709\u4ec0\u4e48\u5171\u540c\u6a21\u5f0f\uff0c\u9700\u8981\u7684\u662f\u53d1\u73b0\u57fa\u5e8f\u3002\u5982\u679c\u5df2\u7ecf\u6709\u4e00\u7ec4\u57fa\u5e8f\uff0c\u60f3\u77e5\u9053\u5b83\u4eec\u51fa\u73b0\u5728\u4ec0\u4e48\u4f4d\u7f6e\uff0c\u9700\u8981\u7684\u662f\u626b\u63cf\u3002\u5982\u679c\u5173\u5fc3\u4e00\u7ec4\u533a\u57df\u662f\u5426\u66f4\u5e38\u51fa\u73b0\u67d0\u7c7b\u6a21\u5f0f\uff0c\u9700\u8981\u7684\u662f\u5bcc\u96c6\u6bd4\u8f83\u3002\u5982\u679c\u5df2\u7ecf\u53d1\u73b0\u4e00\u4e2a\u6a21\u5f0f\uff0c\u60f3\u4e86\u89e3\u5b83\u4e0e\u5df2\u6709\u6570\u636e\u5e93\u4e2d\u7684\u54ea\u4e9b\u6a21\u5f0f\u76f8\u4f3c\uff0c\u9700\u8981\u7684\u662f\u57fa\u5e8f\u95f4\u6bd4\u8f83\u3002<\/p>\n

\n\n\n\n\n\n\n\n\n
\u7814\u7a76\u95ee\u9898<\/th>\n\u53ef\u67e5\u9605\u7684\u5957\u4ef6\u5de5\u5177<\/th>\n\u9996\u5148\u5ba1\u9605\u7684\u5bf9\u8c61<\/th>\n<\/tr>\n<\/thead>\n
\u5e8f\u5217\u91cc\u6709\u4ec0\u4e48\u5bcc\u96c6\u6a21\u5f0f<\/td>\nSTREME<\/td>\n\u8f93\u5165\u96c6\u5408\u3001\u80cc\u666f\u548c\u53d1\u73b0\u7ed3\u679c<\/td>\n<\/tr>\n
\u5df2\u77e5\u6a21\u5f0f\u51fa\u73b0\u5728\u54ea\u91cc<\/td>\nFIMO<\/td>\n\u4f4d\u70b9\u3001\u5e8f\u5217\u548c\u9608\u503c<\/td>\n<\/tr>\n
\u6a21\u5f0f\u5728\u76ee\u6807\u96c6\u5408\u4e2d\u662f\u5426\u5bcc\u96c6<\/td>\nAME<\/td>\n\u6bd4\u8f83\u8bbe\u8ba1\u4e0e\u80cc\u666f<\/td>\n<\/tr>\n
\u53d1\u73b0\u7684\u6a21\u5f0f\u50cf\u54ea\u4e9b\u5df2\u77e5\u6a21\u5f0f<\/td>\nTomtom<\/td>\n\u6a21\u5f0f\u76f8\u4f3c\u6027\u4e0e\u5339\u914d\u8303\u56f4<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

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\u4e8c\u3001\u5148\u6570\u884c\uff0c\u8fd8\u662f\u5148\u6570\u533a\u57df<\/h2>\n

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\n\n\n\n\n\n\n\n
\u4eba\u5de5\u6a21\u5f0f<\/th>\n\u8868\u683c\u884c\u6570<\/th>\n\u542b\u547d\u4e2d\u7684\u5e8f\u5217\u6570<\/th>\n\u4e0d\u533a\u5206\u94fe\u7684\u533a\u95f4\u6570<\/th>\n<\/tr>\n<\/thead>\n
\u7532<\/td>\n3<\/td>\n2<\/td>\n3<\/td>\n<\/tr>\n
\u4e59<\/td>\n2<\/td>\n1<\/td>\n1<\/td>\n<\/tr>\n
\u4e19<\/td>\n1<\/td>\n1<\/td>\n1<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

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\u5b9e\u9645\u6574\u7406\u7ed3\u679c\u65f6\uff0c\u5efa\u8bae\u81f3\u5c11\u540c\u65f6\u4fdd\u7559\u4f4d\u70b9\u8868\u548c\u533a\u57df\u6c47\u603b\u8868\u3002\u4f4d\u70b9\u8868\u7528\u4e8e\u5b9a\u4f4d\uff0c\u533a\u57df\u8868\u7528\u4e8e\u6309\u533a\u57df\u8ba1\u6570\u3002\u4e24\u8868\u4e4b\u95f4\u4f7f\u7528\u7a33\u5b9a\u6807\u8bc6\u8fde\u63a5\uff0c\u5e76\u5199\u660e\u91cd\u590d\u8bb0\u5f55\u7684\u5904\u7406\u65b9\u6cd5\u3002\u8fd9\u6837\u4ee5\u540e\u6539\u9608\u503c\u6216\u6539\u80cc\u666f\u65f6\uff0c\u53ef\u4ee5\u91cd\u65b0\u6c47\u603b\uff0c\u800c\u4e0d\u5fc5\u4ece\u4e00\u5f20\u5df2\u7ecf\u53bb\u91cd\u4e14\u4e22\u5931\u94fe\u4fe1\u606f\u7684\u8868\u91cc\u731c\u6d4b\u539f\u59cb\u7ed3\u6784\u3002<\/p>\n

\u4e09\u3001\u540c\u6837\u56db\u6210\u9633\u6027\uff0c\u6362\u4e00\u4e2a\u80cc\u666f\u5c31\u53ef\u80fd\u6539\u53d8\u7ed3\u8bba<\/h2>\n

\u7b2c\u4e8c\u4e2a\u81ea\u7f16\u7ec3\u4e60\u4fdd\u6301\u76ee\u6807\u96c6\u5408\u5b8c\u5168\u4e0d\u53d8\uff0c\u4e00\u767e\u4e2a\u533a\u57df\u91cc\u6709\u56db\u5341\u4e2a\u542b\u6a21\u5f0f\u3002\u7b2c\u4e00\u79cd\u80cc\u666f\u4e00\u767e\u4e2a\u533a\u57df\u4e2d\u6709\u4e8c\u5341\u4e2a\u542b\u6a21\u5f0f\uff0c\u7b2c\u4e8c\u79cd\u80cc\u666f\u4e00\u767e\u4e2a\u533a\u57df\u4e2d\u6709\u4e03\u5341\u4e2a\u542b\u6a21\u5f0f\u3002\u6211\u4eec\u7528\u56fa\u5b9a\u4e8c\u4e58\u4e8c\u8868\u8ba1\u7b97\u4f18\u52bf\u6bd4\u548c\u5355\u4fa7\u5bcc\u96c6\u65b9\u5411\u7684 Fisher \u7cbe\u786e\u68c0\u9a8c\uff0c\u6ca1\u6709\u8fd0\u884c AME\uff0c\u4e5f\u6ca1\u6709\u6a21\u4eff\u5b83\u7684\u5b8c\u6574\u5185\u90e8\u6d41\u7a0b\u3002<\/p>\n

\n\n\n\n\n\n\n
\u5bf9\u7167\u80cc\u666f<\/th>\n\u76ee\u6807\u542b\u6a21\u5f0f<\/th>\n\u80cc\u666f\u542b\u6a21\u5f0f<\/th>\n\u4f18\u52bf\u6bd4<\/th>\n<\/tr>\n<\/thead>\n
\u80cc\u666f\u7532<\/td>\n40\/100<\/td>\n20\/100<\/td>\n\u7ea6 2.667<\/td>\n<\/tr>\n
\u80cc\u666f\u4e59<\/td>\n40\/100<\/td>\n70\/100<\/td>\n\u7ea6 0.286<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

\u80cc\u666f\u7532\u5bf9\u5e94\u7684\u5355\u4fa7\u663e\u8457\u6027\u503c\u7ea6\u4e3a\u96f6\u70b9\u96f6\u96f6\u4e00\u516d\uff0c\u80cc\u666f\u4e59\u7ea6\u4e3a\u96f6\u70b9\u4e5d\u4e5d\u4e5d\u4e5d\u4e5d\u516d\u3002\u76ee\u6807\u96c6\u5408\u4e00\u6761\u90fd\u6ca1\u6709\u6539\u53d8\uff0c\u7ed3\u8bba\u5374\u4ece\u76f8\u5bf9\u5bcc\u96c6\u8f6c\u5411\u4e0d\u652f\u6301\u8be5\u65b9\u5411\u7684\u5bcc\u96c6\u3002\u540e\u4e00\u4e2a\u6570\u503c\u63a5\u8fd1\u4e00\uff0c\u5e76\u4e0d\u662f\u76f4\u63a5\u8bc1\u660e\u201c\u6ca1\u6709\u4efb\u4f55\u5dee\u5f02\u201d\uff0c\u66f4\u4e0d\u80fd\u81ea\u52a8\u62ff\u6765\u62a5\u544a\u53cd\u65b9\u5411\u7684\u663e\u8457\u6027\uff0c\u56e0\u4e3a\u6211\u4eec\u8fd9\u6b21\u56fa\u5b9a\u8ba1\u7b97\u7684\u662f\u5bcc\u96c6\u65b9\u5411\u7684\u5c3e\u6982\u7387\u3002<\/p>\n

\u8fd9\u4e2a\u7ec3\u4e60\u7684\u4ef7\u503c\u5728\u4e8e\u63ed\u793a\u6bd4\u8f83\u5bf9\u8c61\u3002\u80cc\u666f\u4e0d\u662f\u8f6f\u4ef6\u4e3a\u4e86\u51d1\u591f\u8f93\u5165\u800c\u8981\u6c42\u7684\u4e00\u4efd\u6587\u4ef6\uff0c\u5b83\u5b9a\u4e49\u4e86\u201c\u76f8\u5bf9\u4e8e\u4ec0\u4e48\u66f4\u52a0\u5e38\u89c1\u201d\u3002\u82e5\u76ee\u6807\u533a\u57df\u5168\u90e8\u6765\u81ea\u5f00\u653e\u67d3\u8272\u8d28\uff0c\u800c\u80cc\u666f\u968f\u610f\u6765\u81ea\u5168\u57fa\u56e0\u7ec4\uff0c\u53d1\u73b0\u7684\u6a21\u5f0f\u53ef\u80fd\u6df7\u5408\u53cd\u6620\u5f00\u653e\u533a\u57df\u7684\u4e00\u822c\u7279\u5f81\u4e0e\u771f\u6b63\u5173\u5fc3\u7684\u6761\u4ef6\u5dee\u5f02\u3002\u82e5\u7814\u7a76\u95ee\u9898\u662f\u5f00\u653e\u533a\u57df\u5185\u90e8\u7684\u53d8\u5316\uff0c\u5c31\u9700\u8981\u56f4\u7ed5\u8fd9\u4e2a\u6bd4\u8f83\u91cd\u65b0\u8bbe\u8ba1\u80cc\u666f\u3002<\/p>\n

\u533a\u57df\u957f\u5ea6\u4e5f\u4e0d\u80fd\u5ffd\u7565\u3002\u66f4\u957f\u7684\u5e8f\u5217\u901a\u5e38\u63d0\u4f9b\u66f4\u591a\u53ef\u80fd\u5339\u914d\u7684\u4f4d\u7f6e\uff0c\u5373\u4f7f\u6bcf\u4e2a\u4f4d\u7f6e\u7684\u6a21\u5f0f\u503e\u5411\u4e0d\u53d8\uff0c\u533a\u57df\u4e2d\u81f3\u5c11\u51fa\u73b0\u4e00\u6b21\u7684\u673a\u4f1a\u4e5f\u4f1a\u6539\u53d8\u3002\u78b1\u57fa\u7ec4\u6210\u3001\u91cd\u590d\u5e8f\u5217\u6bd4\u4f8b\u4e0e\u53ef\u68c0\u6d4b\u8303\u56f4\u540c\u6837\u53ef\u80fd\u5f71\u54cd\u6bd4\u8f83\u3002\u5339\u914d\u54ea\u4e9b\u7279\u5f81\u53d6\u51b3\u4e8e\u95ee\u9898\uff0c\u4e0d\u80fd\u628a\u6240\u6709\u5dee\u5f02\u90fd\u673a\u68b0\u6d88\u9664\uff0c\u4e5f\u4e0d\u80fd\u770b\u5230\u54ea\u4e2a\u80cc\u666f\u663e\u8457\u5c31\u9009\u54ea\u4e2a\u80cc\u666f\u3002<\/p>\n

AME \u5b98\u65b9\u6587\u6863<\/a>\u5305\u542b\u5bf9\u7167\u5e8f\u5217\u3001\u6392\u5e8f\u4fe1\u606f\u548c\u4e0d\u540c\u7edf\u8ba1\u8bbe\u7f6e\u7684\u8bf4\u660e\u3002\u672c\u4f8b\u53ea\u8ba1\u7b97\u9884\u5148\u56fa\u5b9a\u7684\u4e24\u4e2a\u5217\u8054\u8868\uff0c\u6ca1\u6709\u641c\u7d22\u6700\u4f18\u5207\u70b9\u3001\u626b\u63cf\u5927\u91cf\u6a21\u5f0f\u6216\u505a\u6a21\u5f0f\u5c42\u9762\u7684\u591a\u91cd\u6821\u6b63\u3002\u56e0\u6b64\uff0c\u672c\u6587\u6570\u503c\u4e0d\u80fd\u5f53\u4f5c\u67d0\u4e2a AME \u547d\u4ee4\u7684\u9884\u671f\u8f93\u51fa\uff0c\u5b83\u53ea\u662f\u5e2e\u52a9\u8bfb\u8005\u5148\u7406\u89e3\u80cc\u666f\u4e3a\u4ec0\u4e48\u4f1a\u6539\u53d8\u95ee\u9898\u672c\u8eab\u3002<\/p>\n

\u56db\u3001\u5148\u7b5b\u6389\u4e0d\u663e\u8457\u7ed3\u679c\uff0c\u518d\u505a\u591a\u91cd\u6821\u6b63\uff0c\u4f1a\u53d1\u751f\u4ec0\u4e48<\/h2>\n

\u7b2c\u4e09\u4e2a\u7ec3\u4e60\u751f\u6210\u516d\u4e2a\u9884\u5148\u5b9a\u4e49\u7684\u68c0\u9a8c\u503c\uff0c\u4f9d\u6b21\u4e3a\u96f6\u70b9\u96f6\u96f6\u96f6\u4e8c\u3001\u96f6\u70b9\u96f6\u96f6\u4e00\u3001\u96f6\u70b9\u96f6\u4e8c\u3001\u96f6\u70b9\u96f6\u56db\u3001\u96f6\u70b9\u4e09\u548c\u96f6\u70b9\u516b\u3002\u811a\u672c\u5728\u5b8c\u6574\u7684\u516d\u4e2a\u68c0\u9a8c\u7ec4\u6210\u7684\u5bb6\u65cf\u4e0a\u6267\u884c\u72ec\u7acb\u7f16\u5199\u7684 BH \u6821\u6b63\uff0c\u518d\u6f14\u793a\u4e00\u79cd\u9519\u8bef\u64cd\u4f5c\uff0c\u5148\u4fdd\u7559\u5c0f\u4e8e\u96f6\u70b9\u96f6\u4e94\u7684\u56db\u9879\uff0c\u518d\u5bf9\u8fd9\u56db\u9879\u6821\u6b63\u3002<\/p>\n

\u5b8c\u6574\u516d\u9879\u6821\u6b63\r\n0.0012, 0.003, 0.04, 0.06, 0.36, 0.8\r\n\r\n\u5148\u7b5b\u9009\u56db\u9879\u518d\u6821\u6b63\r\n0.0008, 0.002, 0.0266667, 0.04\r\n<\/code><\/pre>\n
\u5b8c\u6574\u5bb6\u65cf\u4e2d\u6709\u4e09\u9879\u4f4e\u4e8e\u96f6\u70b9\u96f6\u4e94\uff0c\u9519\u8bef\u5730\u7f29\u5c0f\u5bb6\u65cf\u540e\u53d8\u6210\u56db\u9879\u3002\u539f\u672c\u6821\u6b63\u503c\u96f6\u70b9\u96f6\u516d\u7684\u4e00\u9879\uff0c\u5728\u7b5b\u9009\u540e\u7684\u8868\u4e2d\u53d8\u6210\u96f6\u70b9\u96f6\u56db\u3002\u5b83\u6ca1\u6709\u83b7\u5f97\u65b0\u7684\u6570\u636e\u8bc1\u636e\uff0c\u53ea\u662f\u6821\u6b63\u65f6\u5fd8\u8bb0\u4e86\u5176\u4ed6\u68c0\u9a8c\u3002\u8fd9\u79cd\u64cd\u4f5c\u7279\u522b\u5bb9\u6613\u53d1\u751f\u5728\u53ea\u4e0b\u8f7d\u4e86\u4e00\u5f20\u663e\u8457\u547d\u4e2d\u8868\uff0c\u7136\u540e\u53c8\u5bf9\u5176\u4e2d\u7684\u663e\u8457\u6027\u503c\u91cd\u65b0\u8fd0\u884c\u6821\u6b63\u65f6\u3002<\/p>\n
\u8fd9\u4e2a\u7ec3\u4e60\u4e0d\u662f FIMO \u7684\u6821\u6b63\u7ed3\u679c\u590d\u7b97\uff0c\u4e5f\u6ca1\u6709\u5305\u542b\u5b9e\u9645\u626b\u63cf\u7684\u5b8c\u6574\u68c0\u9a8c\u7a7a\u95f4\u3002\u5b83\u53ea\u8bf4\u660e\u4e00\u4e2a\u4e00\u822c\u6027\u7684\u8ba1\u6570\u95ee\u9898\uff0c\u8868\u91cc\u7559\u4e0b\u591a\u5c11\u884c\uff0c\u4e0d\u7b49\u4e8e\u6700\u521d\u505a\u4e86\u591a\u5c11\u68c0\u9a8c\u3002\u771f\u5b9e\u626b\u63cf\u8fd8\u6d89\u53ca\u5e8f\u5217\u957f\u5ea6\u3001\u57fa\u5e8f\u6570\u91cf\u3001\u94fe\u65b9\u5411\u3001\u9608\u503c\u4e0e\u8f93\u51fa\u622a\u65ad\uff0c\u4e0d\u80fd\u7528\u4e00\u4e2a\u5df2\u7ecf\u7b5b\u8fc7\u7684\u4f4d\u70b9\u8868\u63a8\u65ad\u5b8c\u6574\u6bd4\u8f83\u8303\u56f4\u3002<\/p>\n
FIMO \u6587\u6863<\/a>\u533a\u5206\u5339\u914d\u663e\u8457\u6027\u4e0e\u6821\u6b63\u540e\u7684\u503c\uff0c\u5e76\u8bf4\u660e\u9ed8\u8ba4\u9608\u503c\u9488\u5bf9\u524d\u8005\u3002\u6587\u6863\u8fd8\u6307\u51fa\uff0c\u7eaf\u6587\u672c\u8f93\u51fa\u6a21\u5f0f\u4f1a\u5173\u95ed\u6821\u6b63\u503c\u8ba1\u7b97\uff0c\u4fdd\u5b58\u5339\u914d\u6570\u91cf\u8fbe\u5230\u4e0a\u9650\u65f6\u4e5f\u53ef\u80fd\u5f71\u54cd\u7ed3\u679c\u5b8c\u6574\u6027\u3002\u62ff\u5230\u4e00\u4e2a\u6ca1\u6709\u6821\u6b63\u5217\u7684\u6587\u672c\u6587\u4ef6\uff0c\u4e0d\u80fd\u4ec5\u51ed\u6587\u4ef6\u540d\u5c31\u5ba3\u79f0\u6240\u6709\u7ed3\u679c\u5df2\u7ecf\u63a7\u5236\u4e86\u9519\u8bef\u53d1\u73b0\u7387\u3002<\/p>\n
\u5ba1\u9605\u65f6\u6700\u597d\u540c\u65f6\u67e5\u770b\u547d\u4ee4\u3001\u65e5\u5fd7\u548c\u539f\u59cb\u8f93\u51fa\u8bf4\u660e\u3002\u5c24\u5176\u8981\u786e\u8ba4\u9608\u503c\u4f5c\u7528\u5728\u54ea\u4e00\u5217\u3001\u662f\u5426\u53ea\u8f93\u51fa\u90e8\u5206\u547d\u4e2d\u3001\u8fd0\u884c\u8fc7\u7a0b\u4e2d\u6709\u6ca1\u6709\u5bb9\u91cf\u4e0a\u9650\u76f8\u5173\u63d0\u793a\u3002\u6ca1\u6709\u4fdd\u7559\u8fd9\u4e9b\u4fe1\u606f\u65f6\uff0c\u5b81\u53ef\u660e\u786e\u5199\u6210\u201c\u6309\u5f53\u524d\u8868\u4e2d\u5b57\u6bb5\u7b5b\u9009\u201d\uff0c\u4e5f\u4e0d\u8981\u8865\u51fa\u4e00\u6bb5\u5b9e\u9645\u4e0a\u6ca1\u6709\u6267\u884c\u7684\u7edf\u8ba1\u6d41\u7a0b\u3002<\/p>\n
\u4e94\u3001\u5750\u6807\u8f6c\u6362\u7684\u4e00\u78b1\u57fa\u504f\u5dee\uff0c\u4f1a\u600e\u6837\u6084\u6084\u8fdb\u5165\u7ed3\u679c<\/h2>\n
\u7b2c\u56db\u4e2a\u7ec3\u4e60\u4e13\u95e8\u5904\u7406\u5750\u6807\u3002\u6211\u4eec\u5047\u8bbe\u4ece\u57fa\u56e0\u7ec4\u63d0\u53d6\u4e00\u4e2a\u96f6\u8d77\u70b9\u3001\u53f3\u7aef\u4e0d\u5305\u542b\u7684\u533a\u95f4\uff0c\u8303\u56f4\u4e3a\u4e00\u5343\u5230\u4e00\u5343\u4e8c\u767e\u3002\u4fdd\u5b58\u4e3a\u666e\u901a\u5e8f\u5217\u6807\u8bc6\u7684 FASTA \u540e\uff0c\u4f4d\u70b9\u8868\u4f7f\u7528\u5c40\u90e8\u7684\u4e00\u8d77\u70b9\u3001\u4e24\u7aef\u5305\u542b\u5750\u6807\u3002\u8fd9\u91cc\u7684\u5750\u6807\u5b9a\u4e49\u662f\u7ec3\u4e60\u524d\u63d0\uff0c\u4e0d\u662f\u5bf9\u6240\u6709\u8f6f\u4ef6\u9009\u9879\u548c\u6240\u6709 FASTA \u6807\u9898\u7684\u7edf\u4e00\u5047\u8bbe\u3002<\/p>\n
\u82e5\u6b63\u5411\u63d0\u53d6\u7684\u5e8f\u5217\u4e2d\uff0c\u4e00\u4e2a\u4f4d\u70b9\u4ece\u5341\u4e00\u5230\u5341\u516b\uff0c\u8f6c\u56de\u57fa\u56e0\u7ec4 BED \u5c31\u662f\u4e00\u5343\u96f6\u4e00\u5341\u5230\u4e00\u5343\u96f6\u4e00\u5341\u516b\uff0c\u5bbd\u5ea6\u4ecd\u4e3a\u516b\u3002\u6362\u6210\u5c40\u90e8\u4e8c\u5341\u4e00\u5230\u4e8c\u5341\u516b\u7684\u8d1f\u94fe\u4f4d\u70b9\uff0c\u533a\u95f4\u4e3a\u4e00\u5343\u96f6\u4e8c\u5341\u5230\u4e00\u5343\u96f6\u4e8c\u5341\u516b\u3002\u4f4d\u70b9\u672c\u8eab\u6807\u4e3a\u8d1f\u94fe\uff0c\u4e0d\u4ee3\u8868\u8981\u518d\u6b21\u628a\u6574\u4e2a\u63d0\u53d6\u7a97\u53e3\u7ffb\u8f6c\uff0c\u56e0\u4e3a\u5e8f\u5217\u4ecd\u7136\u662f\u6b63\u5411\u63d0\u53d6\u7684\u3002<\/p>\n
\u6b63\u5411\u63d0\u53d6\r\ngenome_start = window_start + local_start - 1\r\ngenome_end   = window_start + local_end\r\n\r\n\u53cd\u5411\u4e92\u8865\u63d0\u53d6\r\ngenome_start = window_end - local_end\r\ngenome_end   = window_end - local_start + 1\r\n<\/code><\/pre>\n
\u5982\u679c\u63d0\u53d6\u65f6\u5df2\u7ecf\u628a\u6574\u4e2a\u7a97\u53e3\u53cd\u5411\u4e92\u8865\uff0c\u540c\u6837\u7684\u5c40\u90e8\u5341\u4e00\u5230\u5341\u516b\u5219\u5bf9\u5e94\u4e00\u5343\u4e00\u767e\u516b\u5341\u4e8c\u5230\u4e00\u5343\u4e00\u767e\u4e5d\u5341\uff0c\u800c\u4e14\u5c40\u90e8\u6b63\u94fe\u6620\u5c04\u4e3a\u57fa\u56e0\u7ec4\u8d1f\u94fe\u3002\u8981\u533a\u5206\u7684\u662f\u4e24\u4e2a\u5c42\u6b21\uff0c\u5e8f\u5217\u5982\u4f55\u63d0\u53d6\uff0c\u4ee5\u53ca\u5339\u914d\u843d\u5728\u54ea\u6761\u5c40\u90e8\u94fe\u4e0a\u3002\u53ea\u770b\u4f4d\u70b9\u8868\u7684\u6b63\u8d1f\u53f7\u800c\u4e0d\u770b\u63d0\u53d6\u8fc7\u7a0b\uff0c\u5f88\u5bb9\u6613\u628a\u4e00\u4e2a\u672c\u6765\u6b63\u786e\u7684\u5750\u6807\u518d\u7ffb\u8f6c\u4e00\u6b21\u3002<\/p>\n
\u8fd8\u6709\u4e00\u79cd\u53cd\u65b9\u5411\u7684\u9519\u8bef\uff0c\u7a0b\u5e8f\u5df2\u7ecf\u6839\u636e FASTA \u6807\u9898\u89e3\u6790\u51fa\u57fa\u56e0\u7ec4\u5750\u6807\uff0c\u4e0b\u6e38\u811a\u672c\u5374\u518d\u6b21\u52a0\u4e0a\u7a97\u53e3\u8d77\u70b9\u3002\u4e3a\u907f\u514d\u8fd9\u79cd\u60c5\u51b5\uff0c\u5efa\u8bae\u7528\u4e00\u4e2a\u5df2\u77e5\u77ed\u5e8f\u5217\u505a\u5f80\u8fd4\u6838\u9a8c\uff0c\u5148\u68c0\u67e5\u5bbd\u5ea6\u662f\u5426\u4fdd\u6301\uff0c\u518d\u4ece\u57fa\u56e0\u7ec4\u53d6\u56de\u8be5\u533a\u95f4\uff0c\u6309\u94fe\u65b9\u5411\u6bd4\u8f83\u5e8f\u5217\u3002\u8fd9\u4e2a\u5c0f\u68c0\u67e5\u6bd4\u7b49\u5230\u51e0\u4e07\u4e2a\u5cf0\u7684\u5bcc\u96c6\u56fe\u5f02\u5e38\u540e\u518d\u8ffd\u67e5\u5750\u6807\u66f4\u6709\u6548\u3002<\/p>\n
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python3 run.py output\r\n<\/code><\/pre>\n
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